{"pdf_hash": "81c7347b2d837f84ec3751aeb747fe3a38612c97", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. An illustrative case. A-D: Initial MRI findings. E-H: Follow-up imaging after 7 months without surgical intervention.", "width": 1340, "height": 1352, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "66e14d81-173c-41c6-b0f8-72f0078bd180", "label": "a", "points": [[3.2, 0], [3.2, 438.2], [439.3, 438.2], [439.3, 0]], "color": "yellow"}, {"id": "3ba2e742-e6dc-4bb6-a29e-01dc3b62371f", "label": "a", "points": [[452, 2.1], [452, 438.2], [892.3, 438.2], [892.3, 2.1]], "color": "cyan"}, {"id": "13dd0017-a846-4f23-9c34-20bc1ffb6b43", "label": "a", "points": [[902.9, 2.1], [902.9, 442.4], [1334.7, 442.4], [1334.7, 2.1]], "color": "magenta"}, {"id": "96fa41ab-f227-42eb-b1f1-4a701de4f3b9", "label": "a", "points": [[3.2, 448.8], [3.2, 887], [439.3, 887], [439.3, 448.8]], "color": "springgreen"}, {"id": "31f39289-84ff-488a-ac25-cc8948a53b0e", "label": "e", "points": [[454.1, 442.4], [454.1, 891.2], [888.1, 891.2], [888.1, 442.4]], "color": "tomato"}, {"id": "d5759fa7-6047-4a5e-9b88-5542249bfbea", "label": "e", "points": [[902.9, 450.9], [902.9, 889.1], [1336.9, 889.1], [1336.9, 450.9]], "color": "deepskyblue"}, {"id": "adcc210c-8ab9-4bf1-9fef-8f00882362e9", "label": "e", "points": [[5.3, 895.5], [5.3, 1344.3], [441.4, 1344.3], [441.4, 895.5]], "color": "orange"}, {"id": "38010823-258c-4a7f-b5b0-ed185cb5efdc", "label": "e", "points": [[449.9, 899.7], [449.9, 1337.9], [890.2, 1337.9], [890.2, 899.7]], "color": "hotpink"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "An", "start": 8, "end": 10, "id": 4}, {"text": "illustrative", "start": 11, "end": 23, "id": 5}, {"text": "case", "start": 24, "end": 28, "id": 6}, {"text": ".", "start": 28, "end": 29, "id": 7}, {"text": "A", "start": 30, "end": 31, "id": 8}, {"text": "-", "start": 31, "end": 32, "id": 9}, {"text": "D", "start": 32, "end": 33, "id": 10}, {"text": ":", "start": 33, "end": 34, "id": 11}, {"text": "Initial", "start": 35, "end": 42, "id": 12}, {"text": "MRI", "start": 43, "end": 46, "id": 13}, {"text": "findings", "start": 47, "end": 55, "id": 14}, {"text": ".", "start": 55, "end": 56, "id": 15}, {"text": "E", "start": 57, "end": 58, "id": 16}, {"text": "-", "start": 58, "end": 59, "id": 17}, {"text": "H", "start": 59, "end": 60, "id": 18}, {"text": ":", "start": 60, "end": 61, "id": 19}, {"text": "Follow", "start": 62, "end": 68, "id": 20}, {"text": "-", "start": 68, "end": 69, "id": 21}, {"text": "up", "start": 69, "end": 71, "id": 22}, {"text": "imaging", "start": 72, "end": 79, "id": 23}, {"text": "after", "start": 80, "end": 85, "id": 24}, {"text": "7", "start": 86, "end": 87, "id": 25}, {"text": "months", "start": 88, "end": 94, "id": 26}, {"text": "without", "start": 95, "end": 102, "id": 27}, {"text": "surgical", "start": 103, "end": 111, "id": 28}, {"text": "intervention", "start": 112, "end": 124, "id": 29}, {"text": ".", "start": 124, "end": 125, "id": 30}]}
{"pdf_hash": "6ff2ceb4d5c5da0d48d50ba3dcb011dc69dc7818", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Radiologic imaging tests. (A) Enhanced CT showed diffuse enlargement of the thyroid gland and a tumor (arrows) in the right lobe of the thyroid. (B) Thyroidal uptake of radioiodine showed diffuse enlargement of both lobes of the thyroid with homogeneously increased uptake (52.74%).", "width": 614, "height": 1246, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "d99537a5-82d3-49d0-b46b-90e52e756134", "label": "a", "points": [[2, 4.8], [2, 590.9], [611, 590.9], [611, 4.8]], "color": "yellow"}, {"id": "16b2c11e-e7b1-4c13-b698-6f830ff8bcc9", "label": "b", "points": [[13, 654.9], [13, 1244.9], [598, 1244.9], [598, 654.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Radiologic", "start": 9, "end": 19, "id": 2}, {"text": "imaging", "start": 20, "end": 27, "id": 3}, {"text": "tests", "start": 28, "end": 33, "id": 4}, {"text": ".", "start": 33, "end": 34, "id": 5}, {"text": "(", "start": 35, "end": 36, "id": 6}, {"text": "A", "start": 36, "end": 37, "id": 7}, {"text": ")", "start": 37, "end": 38, "id": 8}, {"text": "Enhanced", "start": 39, "end": 47, "id": 9}, {"text": "CT", "start": 48, "end": 50, "id": 10}, {"text": "showed", "start": 51, "end": 57, "id": 11}, {"text": "diffuse", "start": 58, "end": 65, "id": 12}, {"text": "enlargement", "start": 66, "end": 77, "id": 13}, {"text": "of", "start": 78, "end": 80, "id": 14}, {"text": "the", "start": 81, "end": 84, "id": 15}, {"text": "thyroid", "start": 85, "end": 92, "id": 16}, {"text": "gland", "start": 93, "end": 98, "id": 17}, {"text": "and", "start": 99, "end": 102, "id": 18}, {"text": "a", "start": 103, "end": 104, "id": 19}, {"text": "tumor", "start": 105, "end": 110, "id": 20}, {"text": "(", "start": 111, "end": 112, "id": 21}, {"text": "arrows", "start": 112, "end": 118, "id": 22}, {"text": ")", "start": 118, "end": 119, "id": 23}, {"text": "in", "start": 120, "end": 122, "id": 24}, {"text": "the", "start": 123, "end": 126, "id": 25}, {"text": "right", "start": 127, "end": 132, "id": 26}, {"text": "lobe", "start": 133, "end": 137, "id": 27}, {"text": "of", "start": 138, "end": 140, "id": 28}, {"text": "the", "start": 141, "end": 144, "id": 29}, {"text": "thyroid", "start": 145, "end": 152, "id": 30}, {"text": ".", "start": 152, "end": 153, "id": 31}, {"text": "(", "start": 154, "end": 155, "id": 32}, {"text": "B", "start": 155, "end": 156, "id": 33}, {"text": ")", "start": 156, "end": 157, "id": 34}, {"text": "Thyroidal", "start": 158, "end": 167, "id": 35}, {"text": "uptake", "start": 168, "end": 174, "id": 36}, {"text": "of", "start": 175, "end": 177, "id": 37}, {"text": "radioiodine", "start": 178, "end": 189, "id": 38}, {"text": "showed", "start": 190, "end": 196, "id": 39}, {"text": "diffuse", "start": 197, "end": 204, "id": 40}, {"text": "enlargement", "start": 205, "end": 216, "id": 41}, {"text": "of", "start": 217, "end": 219, "id": 42}, {"text": "both", "start": 220, "end": 224, "id": 43}, {"text": "lobes", "start": 225, "end": 230, "id": 44}, {"text": "of", "start": 231, "end": 233, "id": 45}, {"text": "the", "start": 234, "end": 237, "id": 46}, {"text": "thyroid", "start": 238, "end": 245, "id": 47}, {"text": "with", "start": 246, "end": 250, "id": 48}, {"text": "homogeneously", "start": 251, "end": 264, "id": 49}, {"text": "increased", "start": 265, "end": 274, "id": 50}, {"text": "uptake", "start": 275, "end": 281, "id": 51}, {"text": "(", "start": 282, "end": 283, "id": 52}, {"text": "52.74", "start": 283, "end": 288, "id": 53}, {"text": "%", "start": 288, "end": 289, "id": 54}, {"text": ")", "start": 289, "end": 290, "id": 55}, {"text": ".", "start": 290, "end": 291, "id": 56}]}
{"pdf_hash": "968742d6d4211d039e742f76cf39b69f06009f4b", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Effects of LIPUS treatment on brain edema in TBI mice. (a) Representative T2-weighted MRI images at 1 and 4 days post-TBI. The damaged area is defined as a hyperintense region over the right parietal cortex, indicating edema formation. Dotted line shows location of regions of interest. 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{"pdf_hash": "63c351a976c2c73ca05f7e94e5a0a682dfe17e46", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. The distribution of DNA, centrosomes, and microtubules in aphidicolin-injected embryos at various times after injection. Embryos were injected with aphidicolin at about the time of pole cell formation (nuclear cycle 9, see text). They were allowed to develop for various lengths of time before fixation and staining with Rb188 (anti-centrosome) and YIl/2 (anti-tubulin) followed by rhodamine-coupled goat anti-rabbit and fluorescein-coupled mouse anti-rat antibodies. The embryos were finally incubated with Hoeehst 33258 (see Materials and Methods). The figure shows fields from typical embryos fixed 10 (A), 45 (B), and 90 (C) min after injection of the drug. 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{"pdf_hash": "4be96f3ab2b344cba97d34108118115330086679", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Figure 2 Regional distribution of specific [ 3 H]Ro48 8587 binding (a, b) and expression of GluR1 (c, d) and GluR2 (e, f) in coronal rat brain sections corresponding to Figures 14 and 31 of the rat brain atlas (Paxinos and Watson, 1997). Abbreviations: CA1-3: CA1-3 subfields of the hippocampus; CPu: caudate putamen; DG: dentate gyrus of the hippocampus; LaDL: lateral amygdaloid nucleus, dorsolateral part; MeAm: medial amygdaloid nucleus; NAc; nucleus accumbens; Rt: reticular nucleus of the thalamus.", "width": 684, "height": 750, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [2, 3, 4, 17, 18, 19, 20, 21, 22, 23, 24, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "c": [2, 3, 4, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "89ac04f1-82ee-44b6-ba74-1e8bd9653cab", "label": "a", "points": [[18.7, 10.7], [18.7, 232.2], [672.4, 232.2], [672.4, 10.7]], "color": "yellow"}, {"id": "ada83d54-40e4-4b8c-a8eb-171855d07dd8", "label": "b", "points": [[20.8, 258.1], 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{"pdf_hash": "00c8ad067fbe797981136fa5cf1634d42e25d578", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. Images of Case 4. A: MRI shows a hypervascular mass, compatible with angiosarcoma in the right lobe, B: Image shows resected specimen and the site where abscess drainage was performed in his previous surgery, C: Positive immunohistochemical staining for CgA (x200).", "width": 1338, "height": 466, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "c": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53]}, "subfigures": [{"id": "29c02131-5856-4308-8435-26f0b526d740", "label": "a", "points": [[6.7, 2.8], [6.7, 444.6], [437.9, 444.6], [437.9, 2.8]], "color": "yellow"}, {"id": "4052b81e-f19a-45ad-a4ec-659026f9ca91", "label": "b", "points": [[450.6, 17.6], [450.6, 442.5], [890.3, 442.5], [890.3, 17.6]], "color": "cyan"}, {"id": "18e22bc4-8524-4ba7-a72e-fcec7b2b402d", "label": "c", "points": [[907.2, 17.6], [907.2, 436.1], [1336.3, 436.1], [1336.3, 17.6]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Images", "start": 10, "end": 16, "id": 3}, {"text": "of", "start": 17, "end": 19, "id": 4}, {"text": "Case", "start": 20, "end": 24, "id": 5}, {"text": "4", "start": 25, "end": 26, "id": 6}, {"text": ".", "start": 26, "end": 27, "id": 7}, {"text": "A", "start": 28, "end": 29, "id": 8}, {"text": ":", "start": 29, "end": 30, "id": 9}, {"text": "MRI", "start": 31, "end": 34, "id": 10}, {"text": "shows", "start": 35, "end": 40, "id": 11}, {"text": "a", "start": 41, "end": 42, "id": 12}, {"text": "hypervascular", "start": 43, "end": 56, "id": 13}, {"text": "mass", "start": 57, "end": 61, "id": 14}, {"text": ",", "start": 61, "end": 62, "id": 15}, {"text": "compatible", "start": 63, "end": 73, "id": 16}, {"text": "with", "start": 74, "end": 78, "id": 17}, {"text": "angiosarcoma", "start": 79, "end": 91, "id": 18}, {"text": "in", "start": 92, "end": 94, "id": 19}, {"text": "the", "start": 95, "end": 98, "id": 20}, {"text": "right", "start": 99, "end": 104, "id": 21}, {"text": "lobe", "start": 105, "end": 109, "id": 22}, {"text": ",", "start": 109, "end": 110, "id": 23}, {"text": "B", "start": 111, "end": 112, "id": 24}, {"text": ":", "start": 112, "end": 113, "id": 25}, {"text": "Image", "start": 114, "end": 119, "id": 26}, {"text": "shows", "start": 120, "end": 125, "id": 27}, {"text": "resected", "start": 126, "end": 134, "id": 28}, {"text": "specimen", "start": 135, "end": 143, "id": 29}, {"text": "and", "start": 144, "end": 147, "id": 30}, {"text": "the", "start": 148, "end": 151, "id": 31}, {"text": "site", "start": 152, "end": 156, "id": 32}, {"text": "where", "start": 157, "end": 162, "id": 33}, {"text": "abscess", "start": 163, "end": 170, "id": 34}, {"text": "drainage", "start": 171, "end": 179, "id": 35}, {"text": "was", "start": 180, "end": 183, "id": 36}, {"text": "performed", "start": 184, "end": 193, "id": 37}, {"text": "in", "start": 194, "end": 196, "id": 38}, {"text": "his", "start": 197, "end": 200, "id": 39}, {"text": "previous", "start": 201, "end": 209, "id": 40}, {"text": "surgery", "start": 210, "end": 217, "id": 41}, {"text": ",", "start": 217, "end": 218, "id": 42}, {"text": "C", "start": 219, "end": 220, "id": 43}, {"text": ":", "start": 220, "end": 221, "id": 44}, {"text": "Positive", "start": 222, "end": 230, "id": 45}, {"text": "immunohistochemical", "start": 231, "end": 250, "id": 46}, {"text": "staining", "start": 251, "end": 259, "id": 47}, {"text": "for", "start": 260, "end": 263, "id": 48}, {"text": "CgA", "start": 264, "end": 267, "id": 49}, {"text": "(", "start": 268, "end": 269, "id": 50}, {"text": "x200", "start": 269, "end": 273, "id": 51}, {"text": ")", "start": 273, "end": 274, "id": 52}, {"text": ".", "start": 274, "end": 275, "id": 53}]}
{"pdf_hash": "400e166023e6a8fbf78a3757b6c4e5233d637b41", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 \u2013 T1-weighted axial (A), T2-weighted coronal (B), T2-weighted axial (C), and axial fluid-attenuated inversion recovery sequence (D) of magnetic resonance images show ventriculomegaly, cystic encephalomalacia, and extensive subcortical and periventricular white matter loss and hyperintensity in white matter with atrophy.", "width": 834, "height": 886, "subcaptions": {"a": [4, 5, 6, 7, 8, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "b": [10, 11, 12, 13, 14, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "c": [16, 17, 18, 19, 20, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "d": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "c57e207a-8352-447d-b3a6-746a52266958", "label": "a", "points": [[10.5, 0], [10.5, 426.9], [417.7, 426.9], [417.7, 0]], "color": "yellow"}, {"id": "d25ffb54-3abc-402f-a0d2-af0cdcd04955", "label": "c", "points": [[11.9, 444], [11.9, 881.5], [407.1, 881.5], [407.1, 444]], "color": "magenta"}, {"id": "2cee99ab-ece5-4783-b3ca-24fb2c6f7784", "label": "d", "points": [[421.6, 445.3], [421.6, 882.8], [827.4, 882.8], [827.4, 445.3]], "color": "tomato"}, {"id": "6784ac21-5457-49ac-9acc-91ef3930d03f", "label": "b", "points": [[425.9, 6.2], [425.9, 431.1], [827.1, 431.1], [827.1, 6.2]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "T1-weighted", "start": 9, "end": 20, "id": 4}, {"text": "axial", "start": 21, "end": 26, "id": 5}, {"text": "(", "start": 27, "end": 28, "id": 6}, {"text": "A", "start": 28, "end": 29, "id": 7}, {"text": ")", "start": 29, "end": 30, "id": 8}, {"text": ",", "start": 30, "end": 31, "id": 9}, {"text": "T2-weighted", "start": 32, "end": 43, "id": 10}, {"text": "coronal", "start": 44, "end": 51, "id": 11}, {"text": "(", "start": 52, "end": 53, "id": 12}, {"text": "B", "start": 53, "end": 54, "id": 13}, {"text": ")", "start": 54, "end": 55, "id": 14}, {"text": ",", "start": 55, "end": 56, "id": 15}, {"text": "T2-weighted", "start": 57, "end": 68, "id": 16}, {"text": "axial", "start": 69, "end": 74, "id": 17}, {"text": "(", "start": 75, "end": 76, "id": 18}, {"text": "C", "start": 76, "end": 77, "id": 19}, {"text": ")", "start": 77, "end": 78, "id": 20}, {"text": ",", "start": 78, "end": 79, "id": 21}, {"text": "and", "start": 80, "end": 83, "id": 22}, {"text": "axial", "start": 84, "end": 89, "id": 23}, {"text": "fluid", "start": 90, "end": 95, "id": 24}, {"text": "-", "start": 95, "end": 96, "id": 25}, {"text": "attenuated", "start": 96, "end": 106, "id": 26}, {"text": "inversion", "start": 107, "end": 116, "id": 27}, {"text": "recovery", "start": 117, "end": 125, "id": 28}, {"text": "sequence", "start": 126, "end": 134, "id": 29}, {"text": "(", "start": 135, "end": 136, "id": 30}, {"text": "D", "start": 136, "end": 137, "id": 31}, {"text": ")", "start": 137, "end": 138, "id": 32}, {"text": "of", "start": 139, "end": 141, "id": 33}, {"text": "magnetic", "start": 142, "end": 150, "id": 34}, {"text": "resonance", "start": 151, "end": 160, "id": 35}, {"text": "images", "start": 161, "end": 167, "id": 36}, {"text": "show", "start": 168, "end": 172, "id": 37}, {"text": "ventriculomegaly", "start": 173, "end": 189, "id": 38}, {"text": ",", "start": 189, "end": 190, "id": 39}, {"text": "cystic", "start": 191, "end": 197, "id": 40}, {"text": "encephalomalacia", "start": 198, "end": 214, "id": 41}, {"text": ",", "start": 214, "end": 215, "id": 42}, {"text": "and", "start": 216, "end": 219, "id": 43}, {"text": "extensive", "start": 220, "end": 229, "id": 44}, {"text": "subcortical", "start": 230, "end": 241, "id": 45}, {"text": "and", "start": 242, "end": 245, "id": 46}, {"text": "periventricular", "start": 246, "end": 261, "id": 47}, {"text": "white", "start": 262, "end": 267, "id": 48}, {"text": "matter", "start": 268, "end": 274, "id": 49}, {"text": "loss", "start": 275, "end": 279, "id": 50}, {"text": "and", "start": 280, "end": 283, "id": 51}, {"text": "hyperintensity", "start": 284, "end": 298, "id": 52}, {"text": "in", "start": 299, "end": 301, "id": 53}, {"text": "white", "start": 302, "end": 307, "id": 54}, {"text": "matter", "start": 308, "end": 314, "id": 55}, {"text": "with", "start": 315, "end": 319, "id": 56}, {"text": "atrophy", "start": 320, "end": 327, "id": 57}, {"text": ".", "start": 327, "end": 328, "id": 58}]}
{"pdf_hash": "1aed386aecbd7c98e2a31c280d5f4194ab45768a", "fig_key": "Figure7", "fig_uri": "9-Figure7-1.png", "text": "Figure 7. Localization of \u2018H-DPR * ., ,. , I\u2019 6 .J (top), 3H-NBI (middle), and \u2018H-CHA (bottom) binding sites in adjacent coronal sections in the plane of the hippocampus of a pointer dog brain. The distribution of all 3 binding sites is very similar to their distribution in guinea pig brain. The only remarkable difference is their practically identical localization in layers of Ammon\u2019s horn (H), and dentate gyrus (DC). Other structures shown are parietal cortex (CC), superior colliculus (superficial gray, SG), central gray (CG), medial geniculate body (GB), and substantia nigra (,!W). Sections labeled with 3H-NBI and \u2018HCHA were exposed for 8 weeks together with the corresponding sections in Figure 8 because of the relative low binding densities and the low specific activity of the radiolabels as contrasted to the 3H-DPR sections, which were again exposed for 4 weeks. 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{"pdf_hash": "fa6f0db8aec6efbf332a215397b68c07c4cace09", "fig_key": "Figure13", "fig_uri": "15-Figure13-1.png", "text": "Fig 13. Isolation of canine glioma-targeting peptides for delivery of imaging and therapeutic agents. Tumor-specific peptides have many advantages over more traditional antibody based targeting strategies. (A) Canine glioma cells bind to bead-specific peptide sequences in random screening libraries. (B, C) Isolation of bead peptides and conjugation to fluorescent markers allows targeting to canine glioma tumors grown in mouse subcutaneous models.", "width": 906, "height": 582, "subcaptions": {"a": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "b": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76]}, "subfigures": [{"id": "732255d0-164b-4111-8083-811c33326adf", "label": "a", "points": [[5, 3], [5, 576.9], [312.7, 576.9], [312.7, 3]], "color": "yellow"}, {"id": "cee04e24-22c6-4e46-8c92-5783866270f6", "label": "b", "points": [[322.8, 3], [322.8, 576.9], [604.7, 576.9], [604.7, 3]], "color": "cyan"}, {"id": "0b99ddbe-65ab-4e1f-a9d1-30c27cba8346", "label": "b", "points": [[619, -1.3], [619, 576.9], [902.4, 576.9], [902.4, -1.3]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "13", "start": 4, "end": 6, "id": 1}, {"text": ".", "start": 6, "end": 7, "id": 2}, 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{"pdf_hash": "b5d9875a7861facd304f0b53cf29f6aa5637ee08", "fig_key": "Figure8", "fig_uri": "12-Figure8-1.png", "text": "Fig. 8. Label in olfactory tubercle ( O n ) after injection of C2 in animal 93. A. cresyl violet. B. darkfield photomicrograph of coronal nection in (A). Compare to Figure 2B, C.", "width": 512, "height": 1504, "subcaptions": {"a": [20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34]}, "subfigures": [{"id": "8bd84315-975b-4dfc-b69d-11af5a0e953a", "label": "a", "points": [[4.8, 756.9], [4.8, 1501.9], [505.8, 1501.9], [505.8, 756.9]], "color": "yellow"}, {"id": "97ce2ae3-b694-49b2-be27-654cf956de63", "label": "b", "points": [[1.8, 1.9], [1.8, 744.9], [523.8, 744.9], [523.8, 1.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "8", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Label", "start": 8, "end": 13, "id": 4}, {"text": "in", "start": 14, "end": 16, "id": 5}, {"text": "olfactory", "start": 17, "end": 26, "id": 6}, {"text": "tubercle", "start": 27, "end": 35, "id": 7}, {"text": "(", "start": 36, "end": 37, "id": 8}, {"text": "O", "start": 38, "end": 39, "id": 9}, {"text": "n", "start": 40, "end": 41, "id": 10}, {"text": ")", "start": 42, "end": 43, "id": 11}, {"text": "after", "start": 44, "end": 49, "id": 12}, {"text": "injection", "start": 50, "end": 59, "id": 13}, {"text": "of", "start": 60, "end": 62, "id": 14}, {"text": "C2", "start": 63, "end": 65, "id": 15}, {"text": "in", "start": 66, "end": 68, "id": 16}, {"text": "animal", "start": 69, "end": 75, "id": 17}, {"text": "93", "start": 76, "end": 78, "id": 18}, {"text": ".", "start": 78, "end": 79, "id": 19}, {"text": "A.", "start": 80, "end": 82, "id": 20}, {"text": "cresyl", "start": 83, "end": 89, "id": 21}, {"text": "violet", "start": 90, "end": 96, "id": 22}, {"text": ".", "start": 96, "end": 97, "id": 23}, {"text": "B.", "start": 98, "end": 100, "id": 24}, {"text": "darkfield", "start": 101, "end": 110, "id": 25}, {"text": "photomicrograph", "start": 111, "end": 126, "id": 26}, {"text": "of", "start": 127, "end": 129, "id": 27}, {"text": "coronal", "start": 130, "end": 137, "id": 28}, {"text": "nection", "start": 138, "end": 145, "id": 29}, {"text": "in", "start": 146, "end": 148, "id": 30}, {"text": "(", "start": 149, "end": 150, "id": 31}, {"text": "A", "start": 150, "end": 151, "id": 32}, {"text": ")", "start": 151, "end": 152, "id": 33}, {"text": ".", "start": 152, "end": 153, "id": 34}, {"text": "Compare", "start": 154, "end": 161, "id": 35}, {"text": "to", "start": 162, "end": 164, "id": 36}, {"text": "Figure", "start": 165, "end": 171, "id": 37}, {"text": "2B", "start": 172, "end": 174, "id": 38}, {"text": ",", "start": 174, "end": 175, "id": 39}, {"text": "C.", "start": 176, "end": 178, "id": 40}]}
{"pdf_hash": "6b18be6e9ec907ff2544ca95046efc882a6b2484", "fig_key": "Figure1", "fig_uri": "7-Figure1-1.png", "text": "Figure 1. Expression of Gli-1 and Gli-2. Nuclear staining of Gli-1 in (A) a trabecular pattern and (B) a pseudoacinar pattern in HCC tissues, in contrast to normal liver tissue (inset of A). Strong and diffuse nuclear staining of Gli-2 in (C) a trabecular pattern and (D) a pseudoacinar pattern in HCC tissues, in comparison to adjacent normal liver parenchyme (inset of C). HCC, hepatocellular carcinoma. 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{"pdf_hash": "c238d364f2b4bb4bc02a538cf530efaba4fdf52c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Representative enhanced depth imaging OCT images of a patient who showed spontaneous resolution of CSC. Subfoveal choroidal thickness was 475 mm at first visit (a), and decreased to 410 mm after complete absorption of SRF (b). The arrows indicate the subfoveal choroidal thickness, the vertical distance from hyper-reflective line of the RPE Bruch's membrane to innermost hyperreflective line of chorioscleral interface.", "width": 926, "height": 196, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "a9ee801a-86a9-4a16-aa9f-7c525e6285e2", "label": "a", "points": [[19.3, 3.4], [19.3, 170.2], [450.8, 170.2], [450.8, 3.4]], "color": "yellow"}, {"id": "e02f8f2c-73d9-4604-8606-2682b59aa07b", "label": "b", "points": [[469.8, 7.8], [469.8, 164.3], [901.4, 164.3], [901.4, 7.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Representative", "start": 9, "end": 23, "id": 2}, {"text": "enhanced", "start": 24, "end": 32, "id": 3}, {"text": "depth", "start": 33, "end": 38, "id": 4}, {"text": "imaging", "start": 39, "end": 46, "id": 5}, {"text": "OCT", "start": 47, "end": 50, "id": 6}, {"text": "images", "start": 51, "end": 57, "id": 7}, {"text": "of", "start": 58, "end": 60, "id": 8}, {"text": "a", "start": 61, "end": 62, "id": 9}, {"text": "patient", "start": 63, "end": 70, "id": 10}, {"text": "who", "start": 71, "end": 74, "id": 11}, {"text": "showed", "start": 75, "end": 81, "id": 12}, {"text": "spontaneous", "start": 82, "end": 93, "id": 13}, {"text": "resolution", "start": 94, "end": 104, "id": 14}, {"text": "of", "start": 105, "end": 107, "id": 15}, {"text": "CSC", "start": 108, "end": 111, "id": 16}, {"text": ".", "start": 111, "end": 112, "id": 17}, {"text": "Subfoveal", "start": 113, "end": 122, "id": 18}, {"text": "choroidal", "start": 123, "end": 132, "id": 19}, {"text": "thickness", "start": 133, "end": 142, "id": 20}, {"text": "was", "start": 143, "end": 146, "id": 21}, {"text": "475", "start": 147, "end": 150, "id": 22}, {"text": "mm", "start": 151, "end": 153, "id": 23}, {"text": "at", "start": 154, "end": 156, "id": 24}, {"text": "first", "start": 157, "end": 162, "id": 25}, {"text": "visit", "start": 163, "end": 168, "id": 26}, {"text": "(", "start": 169, "end": 170, "id": 27}, {"text": "a", "start": 170, "end": 171, "id": 28}, {"text": ")", "start": 171, "end": 172, "id": 29}, {"text": ",", "start": 172, "end": 173, "id": 30}, {"text": "and", "start": 174, "end": 177, "id": 31}, {"text": "decreased", "start": 178, "end": 187, "id": 32}, {"text": "to", "start": 188, "end": 190, "id": 33}, {"text": "410", "start": 191, "end": 194, "id": 34}, {"text": "mm", "start": 195, "end": 197, "id": 35}, {"text": "after", "start": 198, "end": 203, "id": 36}, {"text": "complete", "start": 204, "end": 212, "id": 37}, {"text": "absorption", "start": 213, "end": 223, "id": 38}, {"text": "of", "start": 224, "end": 226, "id": 39}, {"text": "SRF", "start": 227, "end": 230, "id": 40}, {"text": "(", "start": 231, "end": 232, "id": 41}, {"text": "b", "start": 232, "end": 233, "id": 42}, {"text": ")", "start": 233, "end": 234, "id": 43}, {"text": ".", "start": 234, "end": 235, "id": 44}, {"text": "The", "start": 236, "end": 239, "id": 45}, {"text": "arrows", "start": 240, "end": 246, "id": 46}, {"text": "indicate", "start": 247, "end": 255, "id": 47}, {"text": "the", "start": 256, "end": 259, "id": 48}, {"text": "subfoveal", "start": 260, "end": 269, "id": 49}, {"text": "choroidal", "start": 270, "end": 279, "id": 50}, {"text": "thickness", "start": 280, "end": 289, "id": 51}, {"text": ",", "start": 289, "end": 290, "id": 52}, {"text": "the", "start": 291, "end": 294, "id": 53}, {"text": "vertical", "start": 295, "end": 303, "id": 54}, {"text": "distance", "start": 304, "end": 312, "id": 55}, {"text": "from", "start": 313, "end": 317, "id": 56}, {"text": "hyper", "start": 318, "end": 323, "id": 57}, {"text": "-", "start": 323, "end": 324, "id": 58}, {"text": "reflective", "start": 324, "end": 334, "id": 59}, {"text": "line", "start": 335, "end": 339, "id": 60}, {"text": "of", "start": 340, "end": 342, "id": 61}, {"text": "the", "start": 343, "end": 346, "id": 62}, {"text": "RPE", "start": 347, "end": 350, "id": 63}, {"text": "Bruch", "start": 351, "end": 356, "id": 64}, {"text": "'s", "start": 356, "end": 358, "id": 65}, {"text": "membrane", "start": 359, "end": 367, "id": 66}, {"text": "to", "start": 368, "end": 370, "id": 67}, {"text": "innermost", "start": 371, "end": 380, "id": 68}, {"text": "hyperreflective", "start": 381, "end": 396, "id": 69}, {"text": "line", "start": 397, "end": 401, "id": 70}, {"text": "of", "start": 402, "end": 404, "id": 71}, {"text": "chorioscleral", "start": 405, "end": 418, "id": 72}, {"text": "interface", "start": 419, "end": 428, "id": 73}, {"text": ".", "start": 428, "end": 429, "id": 74}]}
{"pdf_hash": "46dae6f2acb6d69c578d95f361b7d667529ff54e", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. High-resolution temporal bone computed tomography images of unilateral congenital aural atresia combined with microtia. Axial (A) and coronal (B) views showing the dilated vestibular morphology (arrows).", "width": 662, "height": 304, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 21, 22, 23, 24, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "1ccb17d9-b919-46eb-9f95-8b623140722f", "label": "a", "points": [[3.7, 5.1], [3.7, 301], [325.8, 301], [325.8, 5.1]], "color": "yellow"}, {"id": "99e3c193-f6b1-4371-a4a2-49ff74638bcf", "label": "b", "points": [[337.3, 1.9], [337.3, 302.1], [659.4, 302.1], [659.4, 1.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "High", "start": 8, "end": 12, "id": 4}, {"text": "-", "start": 12, "end": 13, "id": 5}, {"text": "resolution", "start": 13, "end": 23, "id": 6}, {"text": "temporal", "start": 24, "end": 32, "id": 7}, {"text": "bone", "start": 33, "end": 37, "id": 8}, {"text": "computed", "start": 38, "end": 46, "id": 9}, {"text": "tomography", "start": 47, "end": 57, "id": 10}, {"text": "images", "start": 58, "end": 64, "id": 11}, {"text": "of", "start": 65, "end": 67, "id": 12}, {"text": "unilateral", "start": 68, "end": 78, "id": 13}, {"text": "congenital", "start": 79, "end": 89, "id": 14}, {"text": "aural", "start": 90, "end": 95, "id": 15}, {"text": "atresia", "start": 96, "end": 103, "id": 16}, {"text": "combined", "start": 104, "end": 112, "id": 17}, {"text": "with", "start": 113, "end": 117, "id": 18}, {"text": "microtia", "start": 118, "end": 126, "id": 19}, {"text": ".", "start": 126, "end": 127, "id": 20}, {"text": "Axial", "start": 128, "end": 133, "id": 21}, {"text": "(", "start": 134, "end": 135, "id": 22}, {"text": "A", "start": 135, "end": 136, "id": 23}, {"text": ")", "start": 136, "end": 137, "id": 24}, {"text": "and", "start": 138, "end": 141, "id": 25}, {"text": "coronal", "start": 142, "end": 149, "id": 26}, {"text": "(", "start": 150, "end": 151, "id": 27}, {"text": "B", "start": 151, "end": 152, "id": 28}, {"text": ")", "start": 152, "end": 153, "id": 29}, {"text": "views", "start": 154, "end": 159, "id": 30}, {"text": "showing", "start": 160, "end": 167, "id": 31}, {"text": "the", "start": 168, "end": 171, "id": 32}, {"text": "dilated", "start": 172, "end": 179, "id": 33}, {"text": "vestibular", "start": 180, "end": 190, "id": 34}, {"text": "morphology", "start": 191, "end": 201, "id": 35}, {"text": "(", "start": 202, "end": 203, "id": 36}, {"text": "arrows", "start": 203, "end": 209, "id": 37}, {"text": ")", "start": 209, "end": 210, "id": 38}, {"text": ".", "start": 210, "end": 211, "id": 39}]}
{"pdf_hash": "efa0ca648909c4ca0b6c6ec8329769b90e0e6b6f", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. a-c. Coronal (a) and axial (b, c) contrast-enhanced CT scan revealing a heterogeneous soft tissue lesion with hyperdense areas involving the right nasal cavity and all ipsilateral sinuses; b, c. The axial cuts showing the lamina papyracea pushed by the tissue bulk that appeared to encroach the medial extraconal space (arrows)", "width": 1458, "height": 548, "subcaptions": {"a": [7, 8, 9, 10, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67]}, "subfigures": [{"id": "00a06336-f2fa-4fe3-b424-c3395ac19427", "label": "a", "points": [[5.8, 4.6], [5.8, 509.1], [478, 509.1], [478, 4.6]], "color": "yellow"}, {"id": "1a64ee64-0733-4930-87b4-7cf45f7c4902", "label": "b", "points": [[496.4, 4.6], [496.4, 499.8], [966.3, 499.8], [966.3, 4.6]], "color": "cyan"}, {"id": "56fcfc49-44ed-4f2b-ac84-aaebc9b52a77", "label": "b", "points": [[987, 0], [987, 504.5], [1452.3, 504.5], [1452.3, 0]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": "-", "start": 11, "end": 12, "id": 4}, {"text": "c", "start": 12, "end": 13, "id": 5}, {"text": ".", "start": 13, "end": 14, "id": 6}, {"text": "Coronal", "start": 15, "end": 22, "id": 7}, {"text": "(", "start": 23, "end": 24, "id": 8}, {"text": "a", "start": 24, "end": 25, "id": 9}, {"text": ")", "start": 25, "end": 26, "id": 10}, {"text": "and", "start": 27, "end": 30, "id": 11}, {"text": "axial", "start": 31, "end": 36, "id": 12}, {"text": "(", "start": 37, "end": 38, "id": 13}, {"text": "b", "start": 38, "end": 39, "id": 14}, {"text": ",", "start": 39, "end": 40, "id": 15}, {"text": "c", "start": 41, "end": 42, "id": 16}, {"text": ")", "start": 42, "end": 43, "id": 17}, {"text": "contrast", "start": 44, "end": 52, "id": 18}, {"text": "-", "start": 52, "end": 53, "id": 19}, {"text": "enhanced", "start": 53, "end": 61, "id": 20}, {"text": "CT", "start": 62, "end": 64, "id": 21}, {"text": "scan", "start": 65, "end": 69, "id": 22}, {"text": "revealing", "start": 70, "end": 79, "id": 23}, {"text": "a", "start": 80, "end": 81, "id": 24}, {"text": "heterogeneous", "start": 82, "end": 95, "id": 25}, {"text": "soft", "start": 96, "end": 100, "id": 26}, {"text": "tissue", "start": 101, "end": 107, "id": 27}, {"text": "lesion", "start": 108, "end": 114, "id": 28}, {"text": "with", "start": 115, "end": 119, "id": 29}, {"text": "hyperdense", "start": 120, "end": 130, "id": 30}, {"text": "areas", "start": 131, "end": 136, "id": 31}, {"text": "involving", "start": 137, "end": 146, "id": 32}, {"text": "the", "start": 147, "end": 150, "id": 33}, {"text": "right", "start": 151, "end": 156, "id": 34}, {"text": "nasal", "start": 157, "end": 162, "id": 35}, {"text": "cavity", "start": 163, "end": 169, "id": 36}, {"text": "and", "start": 170, "end": 173, "id": 37}, {"text": "all", "start": 174, "end": 177, "id": 38}, {"text": "ipsilateral", "start": 178, "end": 189, "id": 39}, {"text": "sinuses", "start": 190, "end": 197, "id": 40}, {"text": ";", "start": 197, "end": 198, "id": 41}, {"text": "b", "start": 199, "end": 200, "id": 42}, {"text": ",", "start": 200, "end": 201, "id": 43}, {"text": "c.", "start": 202, "end": 204, "id": 44}, {"text": "The", "start": 205, "end": 208, "id": 45}, {"text": "axial", "start": 209, "end": 214, "id": 46}, {"text": "cuts", "start": 215, "end": 219, "id": 47}, {"text": "showing", "start": 220, "end": 227, "id": 48}, {"text": "the", "start": 228, "end": 231, "id": 49}, {"text": "lamina", "start": 232, "end": 238, "id": 50}, {"text": "papyracea", "start": 239, "end": 248, "id": 51}, {"text": "pushed", "start": 249, "end": 255, "id": 52}, {"text": "by", "start": 256, "end": 258, "id": 53}, {"text": "the", "start": 259, "end": 262, "id": 54}, {"text": "tissue", "start": 263, "end": 269, "id": 55}, {"text": "bulk", "start": 270, "end": 274, "id": 56}, {"text": "that", "start": 275, "end": 279, "id": 57}, {"text": "appeared", "start": 280, "end": 288, "id": 58}, {"text": "to", "start": 289, "end": 291, "id": 59}, {"text": "encroach", "start": 292, "end": 300, "id": 60}, {"text": "the", "start": 301, "end": 304, "id": 61}, {"text": "medial", "start": 305, "end": 311, "id": 62}, {"text": "extraconal", "start": 312, "end": 322, "id": 63}, {"text": "space", "start": 323, "end": 328, "id": 64}, {"text": "(", "start": 329, "end": 330, "id": 65}, {"text": "arrows", "start": 330, "end": 336, "id": 66}, {"text": ")", "start": 336, "end": 337, "id": 67}]}
{"pdf_hash": "ed03aaa094e0b3c8fcb13f8ac4a746c5f6276e87", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 X-ray and computer tomographic images of a 52-year-old immunocompromised patient after heart transplantation suffering from pulmonary aspergillosis (Aspergillus terreus). a Several lesions on both lungs on X-ray with two of the lesions b showing an air crescent sign (sagittal reconstruction). 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{"pdf_hash": "7ed4606eeb9d69c305de537c0c56013cf4843af2", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: B-scan ultrasonography: (a) Eleven o'clock meridian acquired with a 10 MHz probe (Aviso, Quantel M\u00e9dical) showing a typical retinal tear on B-scan ultrasonography. (b) Superior longitudinal scan acquired with a 20 MHz probe showing a typical retinal tear on B-scan ultrasonography. (c) Superior longitudinal scan acquired with a 20 MHz probe showing a retinal tear associated with retinal detachment. 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{"pdf_hash": "1f3d0722f9b4011a0022bc6de06fb3f7de89f890", "fig_key": "Figure7", "fig_uri": "19-Figure7-1.png", "text": "Figure 7. This figure shows the hardware setup used for a low-cost MI-based EEG system e.g. in [134], [137] where (a) shows the 3D-printed prosthetic arm which was controlled and (b) shows the EEG headset used.", "width": 1212, "height": 428, "subcaptions": {"a": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "575751d6-9d02-4a90-9b71-7c6db3373e6f", "label": "a", "points": [[2, 3.5], [2, 323.3], [607, 323.3], [607, 3.5]], "color": "yellow"}, {"id": "1666667c-6e1d-425f-a004-58e85ac3d287", "label": "b", "points": [[612.7, 7.3], [612.7, 313.7], [1202.4, 313.7], [1202.4, 7.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "7", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "This", "start": 10, "end": 14, "id": 3}, {"text": "figure", "start": 15, "end": 21, "id": 4}, {"text": "shows", "start": 22, "end": 27, "id": 5}, {"text": "the", "start": 28, "end": 31, "id": 6}, {"text": "hardware", "start": 32, "end": 40, "id": 7}, {"text": "setup", "start": 41, "end": 46, "id": 8}, {"text": "used", "start": 47, "end": 51, "id": 9}, {"text": "for", "start": 52, "end": 55, "id": 10}, {"text": "a", "start": 56, "end": 57, "id": 11}, {"text": "low", "start": 58, "end": 61, "id": 12}, {"text": "-", "start": 61, "end": 62, "id": 13}, {"text": "cost", "start": 62, "end": 66, "id": 14}, {"text": "MI", "start": 67, "end": 69, "id": 15}, {"text": "-", "start": 69, "end": 70, "id": 16}, {"text": "based", "start": 70, "end": 75, "id": 17}, {"text": "EEG", "start": 76, "end": 79, "id": 18}, {"text": "system", "start": 80, "end": 86, "id": 19}, {"text": "e.g.", "start": 87, "end": 91, "id": 20}, {"text": "in", "start": 92, "end": 94, "id": 21}, {"text": "[", "start": 95, "end": 96, "id": 22}, {"text": "134", "start": 96, "end": 99, "id": 23}, {"text": "]", "start": 99, "end": 100, "id": 24}, {"text": ",", "start": 100, "end": 101, "id": 25}, {"text": "[", "start": 102, "end": 103, "id": 26}, {"text": "137", "start": 103, "end": 106, "id": 27}, {"text": "]", "start": 106, "end": 107, "id": 28}, {"text": "where", "start": 108, "end": 113, "id": 29}, {"text": "(", "start": 114, "end": 115, "id": 30}, {"text": "a", "start": 115, "end": 116, "id": 31}, {"text": ")", "start": 116, "end": 117, "id": 32}, {"text": "shows", "start": 118, "end": 123, "id": 33}, {"text": "the", "start": 124, "end": 127, "id": 34}, {"text": "3D", "start": 128, "end": 130, "id": 35}, {"text": "-", "start": 130, "end": 131, "id": 36}, {"text": "printed", "start": 131, "end": 138, "id": 37}, {"text": "prosthetic", "start": 139, "end": 149, "id": 38}, {"text": "arm", "start": 150, "end": 153, "id": 39}, {"text": "which", "start": 154, "end": 159, "id": 40}, {"text": "was", "start": 160, "end": 163, "id": 41}, {"text": "controlled", "start": 164, "end": 174, "id": 42}, {"text": "and", "start": 175, "end": 178, "id": 43}, {"text": "(", "start": 179, "end": 180, "id": 44}, {"text": "b", "start": 180, "end": 181, "id": 45}, {"text": ")", "start": 181, "end": 182, "id": 46}, {"text": "shows", "start": 183, "end": 188, "id": 47}, {"text": "the", "start": 189, "end": 192, "id": 48}, {"text": "EEG", "start": 193, "end": 196, "id": 49}, {"text": "headset", "start": 197, "end": 204, "id": 50}, {"text": "used", "start": 205, "end": 209, "id": 51}, {"text": ".", "start": 209, "end": 210, "id": 52}]}
{"pdf_hash": "a01b549c7bf1e8808abf3e97faec20baef358c8e", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 Radiological parameter measurement methods. a The coronal Cobb angle (CA) is measured from the superior end plate of the cephalad end vertebra and the inferior end plate of the caudal end vertebra on the coronal plane; the coronal vertical axis (CVA) is defined as the distance from a perpendicular line drawn from the superior end plate of S1 vertebral body to the C7 plumb line on the coronal plane. b The sagittal vertical axis (SVA) is defined as the distance from a perpendicular line drawn from the superior end plate of S1 vertebral body to the C7 plumb line on lateral radiographs; the thoracic kyphosis (TK) is measured from the upper end plate of T2 to the lower end plate of T12; the lumbar lordosis (LL) is measured from the upper end plate of T12 to the upper end plate of S1; the sacral slope (SS) is defined as the angle between the cranial sacral end plate and a horizontal line; the pelvic incidence (PI) is defined as the angle subtend by a line connecting the center of the femoral head to the center of the cephalad end plate of S1 and a perpendicular line from the upper end plate of S1; the pelvic tilt (PT) is measured as the angle between the vertical axis and the line through the midpoint of the sacral end plate to femoral heads axis", "width": 852, "height": 914, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78], "b": [79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 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{"pdf_hash": "acb6bb938b36e366074e9e372e29aacb626806c6", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig 1. A typical example of the BRB maneuver attempted in the case of a 34 year-old woman with a fibroid in a forward-bent uterus. A. A sagittal survey scan showed that the bowel loops (arrow) were interposed between the uterus and the anterior abdominal wall. F and U indicate the target fibroid and the urinary bladder respectively. Dotted lines delineate the margins of each structure, and transparent orange triangles represent the planned HIFU beam path. B. After filling with 500 mL of saline, the urinary bladder (U) was distended and displaced the uterus cranially. However, the interposed bowel loops (arrow) were still in the anticipated sonication path. F indicates the target fibroid. Dotted lines delineate the margins of each structure. C. The rectum (R) was filled with 150 mL of gel. The distended rectum pushed the uterine cervix and the uterus antero-cranially, which displaced the bowel loops (arrow) out of the anticipated sonication path. F indicates the target fibroid and U indicates the urinary bladder. Dotted lines delineate the margins of each structure. D. The uterus descended after drainage of the urinary bladder (U), although the previouslyinterposed bowel loops (arrow) remained out of the anticipated sonication path. After a successful BRB maneuver, MR-HIFU ablation was performed. F indicates the target fibroid and R indicates the rectum. 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{"pdf_hash": "3a94e95c9f3ffa9fe9a8ef7034edb06d49f37d61", "fig_key": "Figure14", "fig_uri": "12-Figure14-1.png", "text": "Figure 14. Bile duct stricture due to intrahepatic duct stones 3 years after left lobectomy in a 50-year-old man who presented with jaundice. The patient's serum bilirubin level was elevated (12.43 mg/dL [212.6 \u00b5mol/L]). (a) Coronal T2-weighted RARE image shows a stricture (arrow) and dilatation of the proximal intrahepatic ducts. (b) Gd-EOB-DTPA-enhanced T1-weighted 3D GRE image obtained 60 minutes after injection shows no excretion of contrast material into the right main hepatic duct (arrow). 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{"pdf_hash": "98a11f6aa5dfdeed24cd48b8f38a3ed6cb8782d7", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4. Dark-field photomicrograph to show the distribution of 5-HT 1A receptor mRNA expression in the vicinity of the paraventricular nucleus of the hypothalamus (PVH) (A). Dashed line defines the nuclear border of the PVH to emphasise the absence of the transcript relative to the distinct cluster of 5-HT 1A receptor expressing cells within the zona incerta (ZI). Scatterplot (B) showing a significant positive correlation between plasma oestradiol concentrations and 5-HT 1A mRNA levels in the ZI of females. 3V, third ventricle. Adapted with permission from Goel et al. 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{"pdf_hash": "63a59ec0717f96156bb41de1b2e37194747e71ef", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. MRI before treatment. A. Sagittal view, posterior effusion at C2. B. Axial view, hypersignal of C2 with no signs of epiduritis.", "width": 850, "height": 644, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "6e8d6aed-bbd3-48d1-a614-2bf2e3f835b2", "label": "a", "points": [[1.3, 1.3], [1.3, 641.9], [331.7, 641.9], [331.7, 1.3]], "color": "yellow"}, {"id": "d67df041-c29c-4f99-91fe-59de57b95fce", "label": "b", "points": [[350.5, 1.3], [350.5, 523.7], [848.7, 523.7], [848.7, 1.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "MRI", "start": 8, "end": 11, "id": 4}, {"text": "before", "start": 12, "end": 18, "id": 5}, {"text": "treatment", "start": 19, "end": 28, "id": 6}, {"text": ".", "start": 28, "end": 29, "id": 7}, {"text": "A.", "start": 30, "end": 32, "id": 8}, {"text": "Sagittal", "start": 33, "end": 41, "id": 9}, {"text": "view", "start": 42, "end": 46, "id": 10}, {"text": ",", "start": 46, "end": 47, "id": 11}, {"text": "posterior", "start": 48, "end": 57, "id": 12}, {"text": "effusion", "start": 58, "end": 66, "id": 13}, {"text": "at", "start": 67, "end": 69, "id": 14}, {"text": "C2", "start": 70, "end": 72, "id": 15}, {"text": ".", "start": 72, "end": 73, "id": 16}, {"text": "B.", "start": 74, "end": 76, "id": 17}, {"text": "Axial", "start": 77, "end": 82, "id": 18}, {"text": "view", "start": 83, "end": 87, "id": 19}, {"text": ",", "start": 87, "end": 88, "id": 20}, {"text": "hypersignal", "start": 89, "end": 100, "id": 21}, {"text": "of", "start": 101, "end": 103, "id": 22}, {"text": "C2", "start": 104, "end": 106, "id": 23}, {"text": "with", "start": 107, "end": 111, "id": 24}, {"text": "no", "start": 112, "end": 114, "id": 25}, {"text": "signs", "start": 115, "end": 120, "id": 26}, {"text": "of", "start": 121, "end": 123, "id": 27}, {"text": "epiduritis", "start": 124, "end": 134, "id": 28}, {"text": ".", "start": 134, "end": 135, "id": 29}]}
{"pdf_hash": "c4d089f1ac85da73ba577cafe887662b1adc58ee", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Patient 1 MRI images. All images are sagittal in midline. Panels in the left column (A,C) are T2-weighted, fast-spin echo, whereas those in the right column (B,D) are T1-weighted with contrast (T1 + Gd). Panels shown in the upper row (A,B) are postoperative, following initial gross total resection. Resection of the vertebrae caudal to S1 is indicated with the blue arrow. Panels in the lower row (C,D) were taken at time of recurrence. A large, heterogeneous mass extending rostrally almost to S1 and dorsally almost to the skin is present (blue arrows). 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{"pdf_hash": "b987ab7ea1728753a890a1c4c0ebe598b85a0142", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Patient 1: (A) Sagittal and (B) transverse T2-weighted MRI with contrast of the lumbosacral spine shows a rim enhancing cystic lesion (white arrow) centrally located at the L3/4 level compressing onto the cauda equina (grey arrow). Patient 2: (C) Transverse and (D) sagittal T2-weighted MRI image shows Grade I spondylolisthesis and spinal stenosis at the L4/5 level being compressed by a huge cystic structure (white arrow) with a thick cystic wall onto the cauda equina (grey arrow).", "width": 1238, "height": 748, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [2, 3, 4, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "c": [48, 49, 50, 51, 52, 53, 54, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98], "d": [48, 49, 50, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 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{"pdf_hash": "5dd80841cfa8fbf952df8516dd9ff3e4233b977f", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Figure 6. The first transmembrane region of LBR sorts/3-galactosidase to the inner nuclear membrane. (A) COS-1 cells transfected with/3gal-TM1 (B) were fixed and permeabilized 24 h after transfection and processed for indirect immunofluorescence microscopy by staining with mouse anti-/3-galactosidase antibodies, followed by anti-mouse IgG-FITC. (B) shows the amino acid sequence encoded by the chick p58 sequence contained in the/3gal-TM1 construct. The stippled box encloses the predicted membrane spanning segment. Bar, 10 #m.", "width": 662, "height": 762, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "b": [58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93]}, "subfigures": [{"id": "f6772689-3a95-4a2a-b460-03a6ec6a9f0d", "label": "a", "points": [[97.8, 7.1], [97.8, 484], [522.4, 484], [522.4, 7.1]], "color": "yellow"}, {"id": "636fd87f-c4ab-4c9b-9952-8173618f3b82", "label": "b", "points": [[2.7, 548.3], [2.7, 733.4], [655.2, 733.4], [655.2, 548.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "The", "start": 10, "end": 13, "id": 3}, {"text": "first", "start": 14, "end": 19, "id": 4}, {"text": "transmembrane", "start": 20, 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{"pdf_hash": "38a7221418ac93b8c67a6f35f366040e8e563efb", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Genome organization is dominated by folding of chromatin into large-scale chromatin domains. (A) HeLa cells imaged live by deconvolution light microscopy using Hoechst DNA staining. (B) TEM image of HeLa cell nucleus in permeabilized cell reveals large-scale chromatin domains with heavy metal staining. Bar, 500 nm. (C) Computational slice from EM tomography reconstruction reveals large-scale chromatin fiberlike domains formed by the folding of 10-nm and 30-nm chromatin, corresponding to hundreds to thousands of kilobases of DNA. Bar, 200 nm. (D) Similar large-scale chromatin organization is visualized by TEM energy-loss imaging of the phosphorus distribution within cells fixed directly without permeabilization. (Image courtesy of Michael Hendzel, University of Alberta.)", "width": 732, "height": 764, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61], "c": [62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102], "d": [103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130]}, "subfigures": [{"id": "04696331-7462-405e-b535-51b004f6b050", "label": "a", "points": [[360.2, 388.3], [360.2, -0.2], [1.8, -0.2], [1.8, 388.3]], "color": "yellow"}, {"id": "570b9ab0-12c1-4d7c-8a76-2aba0811f3f7", "label": "b", "points": [[375.3, 2.1], [375.3, 393], [729.1, 393], [729.1, 2.1]], "color": "cyan"}, {"id": "a975ef28-ed9f-403c-ac9d-2682155f14fc", "label": "c", 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{"pdf_hash": "d0dc476dc658cc8c8c55439d6d319c03420e7c48", "fig_key": "Figure8", "fig_uri": "5-Figure8-1.png", "text": "Figure 8. a\u2013d. Malignant phyllodes tumor. Axial T2-weighted image (a) shows an irregular and markedly hyperintense lesion (arrow) compared with fibroglandular tissue. Subtraction image (b) reveals heterogeneous enhancement (arrow). The lesion demonstrated wash-out kinetic (not shown). The lesion was categorized as BI-RADS category 4c. Histopathologic examination (c, H-E, \u00d720) demonstrates leaf-like pattern consisting of slits lined with double stratified epithelium (arrows) surrounded by stromal proliferation and (d, H-E, \u00d7100) increased number of atypical mitosis (arrows) of malignant phylloid tumor.", "width": 1418, "height": 272, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "c": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97], "d": [99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120]}, "subfigures": [{"id": "3cdd250d-f4ca-4348-a3a9-7b82a168a14d", "label": "a", "points": [[3.4, 4.1], [3.4, 250.5], [339.4, 250.5], [339.4, 4.1]], "color": "yellow"}, {"id": "ecb365cb-ea17-4831-a452-6d1aa619f2a2", "label": "b", "points": [[359.6, 4.1], [359.6, 246], [688.9, 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{"pdf_hash": "aaf8727c85e8051bdcc2d011026a13a2b1a882e6", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5 - A) Coronal T2 WI showing cold abscess and bone marrow edema of the femoral neck (white arrow) in a case of tuberculous arthritis (TB); B) T1 WI post-contrast Fat Sat showing multilocular abscess cavities in a case of TB arthritis (white arrow); C) T1 WI post-contrast Fat Sat showing multilocular abscess cavities in another case of TB arthritis (white arrow); D) Coronal T2 weighted image showing osteomyelitis of the left femoral shaft (white arrow); E) Axial T2 Fat Sat showing left hip septic arthritis with edema and erosions of the femoral head and acetabulum (white arrow).", "width": 802, "height": 894, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "c": [57, 58, 59, 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{"pdf_hash": "93d0f3a03f07c1b41e2b1f17a3417ea98783db34", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4 Imaging study after left antero-lateral approach (revision surgery). a Coronal CT with bone windows: effective foraminal decompression on the left side; note the screws of the arthrodesis which remained untouched. b axial CT: good left-sided decompression; note that the plate does not obstruct the visual axis and the working space", "width": 474, "height": 1202, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "8df184aa-cf8d-44a6-8a72-5606e5673588", "label": "a", "points": [[0.5, 1.8], [0.5, 743.8], [473.5, 743.8], [473.5, 1.8]], "color": "yellow"}, {"id": "ffa7f5a5-b36e-4d6e-b7e8-3507543e581e", "label": "b", "points": [[2.5, 753.3], [2.5, 1200.3], [472.5, 1200.3], [472.5, 753.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Imaging", "start": 7, "end": 14, "id": 3}, {"text": "study", "start": 15, "end": 20, "id": 4}, {"text": "after", "start": 21, "end": 26, "id": 5}, {"text": "left", "start": 27, "end": 31, "id": 6}, {"text": "antero", "start": 32, "end": 38, "id": 7}, {"text": "-", "start": 38, "end": 39, "id": 8}, {"text": "lateral", "start": 39, "end": 46, "id": 9}, {"text": "approach", "start": 47, "end": 55, "id": 10}, {"text": "(", "start": 56, "end": 57, "id": 11}, {"text": "revision", "start": 57, "end": 65, "id": 12}, {"text": "surgery", "start": 66, "end": 73, "id": 13}, {"text": ")", "start": 73, "end": 74, "id": 14}, {"text": ".", "start": 74, "end": 75, "id": 15}, {"text": "a", "start": 76, "end": 77, "id": 16}, {"text": "Coronal", "start": 78, "end": 85, "id": 17}, {"text": "CT", "start": 86, "end": 88, "id": 18}, {"text": "with", "start": 89, "end": 93, "id": 19}, {"text": "bone", "start": 94, "end": 98, "id": 20}, {"text": "windows", "start": 99, "end": 106, "id": 21}, {"text": ":", "start": 106, "end": 107, "id": 22}, {"text": "effective", "start": 108, "end": 117, "id": 23}, {"text": "foraminal", "start": 118, "end": 127, "id": 24}, {"text": "decompression", "start": 128, "end": 141, "id": 25}, {"text": "on", "start": 142, "end": 144, "id": 26}, {"text": "the", "start": 145, "end": 148, "id": 27}, {"text": "left", "start": 149, "end": 153, "id": 28}, {"text": "side", "start": 154, "end": 158, "id": 29}, {"text": ";", "start": 158, "end": 159, "id": 30}, {"text": "note", "start": 160, "end": 164, "id": 31}, {"text": "the", "start": 165, "end": 168, "id": 32}, {"text": "screws", "start": 169, "end": 175, "id": 33}, {"text": "of", "start": 176, "end": 178, "id": 34}, {"text": "the", "start": 179, "end": 182, "id": 35}, {"text": "arthrodesis", "start": 183, "end": 194, "id": 36}, {"text": "which", "start": 195, "end": 200, "id": 37}, {"text": "remained", "start": 201, "end": 209, "id": 38}, {"text": "untouched", "start": 210, "end": 219, "id": 39}, {"text": ".", "start": 219, "end": 220, "id": 40}, {"text": "b", "start": 221, "end": 222, "id": 41}, {"text": "axial", "start": 223, "end": 228, "id": 42}, {"text": "CT", "start": 229, "end": 231, "id": 43}, {"text": ":", "start": 231, "end": 232, "id": 44}, {"text": "good", "start": 233, "end": 237, "id": 45}, {"text": "left", "start": 238, "end": 242, "id": 46}, {"text": "-", "start": 242, "end": 243, "id": 47}, {"text": "sided", "start": 243, "end": 248, "id": 48}, {"text": "decompression", "start": 249, "end": 262, "id": 49}, {"text": ";", "start": 262, "end": 263, "id": 50}, {"text": "note", "start": 264, "end": 268, "id": 51}, {"text": "that", "start": 269, "end": 273, "id": 52}, {"text": "the", "start": 274, "end": 277, "id": 53}, {"text": "plate", "start": 278, "end": 283, "id": 54}, {"text": "does", "start": 284, "end": 288, "id": 55}, {"text": "not", "start": 289, "end": 292, "id": 56}, {"text": "obstruct", "start": 293, "end": 301, "id": 57}, {"text": "the", "start": 302, "end": 305, "id": 58}, {"text": "visual", "start": 306, "end": 312, "id": 59}, {"text": "axis", "start": 313, "end": 317, "id": 60}, {"text": "and", "start": 318, "end": 321, "id": 61}, {"text": "the", "start": 322, "end": 325, "id": 62}, {"text": "working", "start": 326, "end": 333, "id": 63}, {"text": "space", "start": 334, "end": 339, "id": 64}]}
{"pdf_hash": "8a4828541b894b4f4b4f51cab0e28ba88987a293", "fig_key": "Figure4", "fig_uri": "9-Figure4-1.png", "text": "Figure 4. Expression of Gli1 from the Gli2 locus did not change neural tube patterning in the absence of Smo. Transverse sections of E10.5 embryos processed for immunofluorescence analyses. (A-C) Foxa2 was expressed in the floor plates of the wild type (A) and Gli2 1ki/1ki (B), but not in the Gli2 1ki/1ki ;Smo \u2212/\u2212 (C) neural tubes. (D-F) Nkx2.2 labeled V3 interneurons in the wild type (D) and Gli2 1ki/1ki (E), but was absent in Gli2 1ki/1ki ;Smo \u2212/\u2212 (F) neural tubes. (G-I) Olig2 labels motor neuron progenitors in the wild type (G) and Gli2 1ki/1ki (H), but not in Gli2 1ki/1ki ;Smo \u2212/\u2212 (I) neural tubes. (J-L) Nkx6.1 was expressed in the wild type (J) and Gli2 1ki/1ki (K), but not in Gli2 1ki/1ki ;Smo \u2212/\u2212 (L) neural tubes. (M-O) Pax7 was expressed in the dorsal region of the wild type (M) and Gli2 1ki/1ki (N), and was expanded ventrally in the Gli2 1ki/1ki ;Smo \u2212/\u2212 (O) neural tubes. Dashed lines outline the neural tubes and brackets mark the expression domains. 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{"pdf_hash": "eecd024bbca5431a20c4056c501ecd52eee82ae9", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1a-f. Radiological findings of patients with autoimmune pancreatitis. a Diffuse enlargement of the pancreas showing delayed enhancement on computed tomography scan. b A hypointense capsule-like rim surrounding the swollen pancreas on a T2-weighted magnetic resonance image. c Diffuse hypoechoic swollen pancreas with hyperechoic spots on US. d Diffuse irregular narrowing of the main pancreatic duct on endoscopic retrograde pancreatography. Degree of narrowing varies. e Stenosis of the lower bile duct and segmental narrowing of the main pancreatic duct of the pancreatic head on endoscopic retrograde cholangiopancreatography. 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{"pdf_hash": "5301d378a01a3532db346b98aeacb28b523f1884", "fig_key": "Figure19", "fig_uri": "23-Figure19-1.png", "text": "Fig 19. Time courses showing the fate of nuclei following CAT fusion. (A1-A3) One nucleus within the box is intact and green (A2) whilst another nucleus in the same hypha and within the box shows faint dispersed red fluorescence, indicative of degradation (A2). The overlay images show that there is no colocalization of the green and the faint red nucleus (A3). (B1-B3) Two nuclei (asterisk) containing both H1-GFP (B1) and H1-mCherry (B2) appear yellow in the overlay images (B3). A1-A3 and B1-B3 are overlays of the green fluorescence, red fluorescence and brightfield channels. H1-GFP and H1-mCherry strains were incubated for 72 h in 1% PDB supplemented with 25 mM NaNO 3 . 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{"pdf_hash": "29d35bc9d84e1cf48a598bfcec7aed7b9f6d485d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Sagittal (a) and axial T2w (c) and sagittal (b) and axial gadolinium T1w MTI (d) showing the normalization of the picture of case #1 1 month after surgery and immediately after the antibiotic therapy. The caudal roots are clearly visible and decompressed (asterisks), and no tissue occupying the left L4-L5 foramen is visible (arrow)", "width": 1008, "height": 510, "subcaptions": {"a": [3, 4, 5, 6, 9, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "b": [14, 15, 16, 17, 22, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "c": [8, 9, 10, 11, 12, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "d": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46]}, "subfigures": [{"id": "19e758cc-2992-4bbc-ae30-c162c66415ba", "label": "a", "points": [[43.3, 22.8], [43.3, 473.5], [323.5, 473.5], [323.5, 22.8]], "color": "yellow"}, {"id": "b31a591c-ff36-4883-a86e-d2fb1a678823", "label": "b", "points": [[345.8, 16.5], [345.8, 478.3], [603.8, 478.3], [603.8, 16.5]], "color": "cyan"}, {"id": "da860b6e-820e-48ed-bc60-9ad6b663db9f", 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{"pdf_hash": "0c0409f44193f637dc8a6c4e258c7d92db039f50", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. A 77-year-old male patient with LMGC. (a) Solitary tumor with a 4-cm diameter in S2 (arrow) was irradiated with PBT at a dose of 72.6 Gy (RBE)/22 fractions with the patient in the prone position. Isodose lines represent, from the inside to the outside, 95% to 10% of the dose at the isocenter. (b) CT 3.8 years after PBT. 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{"pdf_hash": "86b25c4bdf988b3fbf001ee2df92ebe13a2e6b23", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 (A-C): (A) Post right common carotid angiogram shows occlusion of distal external carotid artery (thin white arrow). (B) Plain skull radiograph in anteroposterior view shows the coil mass and glue (NBCA) cast (thin white arrow). (C) CT angiography of the neck vessels after 4 weeks shows complete thrombosis of the pseudoaneurysm and reduction of its size with coil mass in the distal external carotid artery (thin white arrow) C B A Figure 1 (A-D): (A) Clinical picture shows right preauricular swelling with staples. (B) CT angiography of the neck vessels shows a narrow neck (thin arrow) pseudoaneurysm arising from the right distal ECA. Fundus of the pseudoaneurysm (thick arrow) is lying just deep to the skin. (C) Right ECA angiogram shows pseudoaneurysm (thick white arrow) from the distal ECA (thick black arrow) with rent (thin arrow) just at the origin of STA (curved arrow). 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{"pdf_hash": "d4a5f83bbd2ef32ce02c206da91c83a6004aed4d", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3 Gallium and positron emission tomography (PET) scans. (A) Increased gallium-67-avid radioactivities in the anterior mediastinum in gallium scan. (B) Increased fluorodeoxyglucose (FDG)-avid uptake mass in the anterior mediastinum in PET scan (maximum standardized uptake value (SUVmax) early: 3.5, delayed: 4.2).", "width": 688, "height": 980, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "fc7b1236-088c-406b-b78d-d5a70f52d401", "label": "a", "points": [[87.3, 37.9], [87.3, 568.3], [563.3, 568.3], [563.3, 37.9]], "color": "yellow"}, {"id": "6ce09773-bc48-4f15-82ee-44c318e41dab", "label": "b", "points": [[15.5, 606.8], [15.5, 978.5], [654.6, 978.5], [654.6, 606.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "Gallium", "start": 9, "end": 16, "id": 2}, {"text": "and", "start": 17, "end": 20, "id": 3}, {"text": "positron", "start": 21, "end": 29, "id": 4}, {"text": "emission", "start": 30, "end": 38, "id": 5}, {"text": "tomography", "start": 39, "end": 49, "id": 6}, {"text": "(", "start": 50, "end": 51, "id": 7}, {"text": "PET", "start": 51, "end": 54, "id": 8}, {"text": ")", "start": 54, "end": 55, "id": 9}, {"text": "scans", "start": 56, "end": 61, "id": 10}, {"text": ".", "start": 61, "end": 62, "id": 11}, {"text": "(", "start": 63, "end": 64, "id": 12}, {"text": "A", "start": 64, "end": 65, "id": 13}, {"text": ")", "start": 65, "end": 66, "id": 14}, {"text": "Increased", "start": 67, "end": 76, "id": 15}, {"text": "gallium-67-avid", "start": 77, "end": 92, "id": 16}, {"text": "radioactivities", "start": 93, "end": 108, "id": 17}, {"text": "in", "start": 109, "end": 111, "id": 18}, {"text": "the", "start": 112, "end": 115, "id": 19}, {"text": "anterior", "start": 116, "end": 124, "id": 20}, {"text": "mediastinum", "start": 125, "end": 136, "id": 21}, {"text": "in", "start": 137, "end": 139, "id": 22}, {"text": "gallium", "start": 140, "end": 147, "id": 23}, {"text": "scan", "start": 148, "end": 152, "id": 24}, {"text": ".", "start": 152, "end": 153, "id": 25}, {"text": "(", "start": 154, "end": 155, "id": 26}, {"text": "B", "start": 155, "end": 156, "id": 27}, {"text": ")", "start": 156, "end": 157, "id": 28}, {"text": "Increased", "start": 158, "end": 167, "id": 29}, {"text": "fluorodeoxyglucose", "start": 168, "end": 186, "id": 30}, {"text": "(", "start": 187, "end": 188, "id": 31}, {"text": "FDG)-avid", "start": 188, "end": 197, "id": 32}, {"text": "uptake", "start": 198, "end": 204, "id": 33}, {"text": "mass", "start": 205, "end": 209, "id": 34}, {"text": "in", "start": 210, "end": 212, "id": 35}, {"text": "the", "start": 213, "end": 216, "id": 36}, {"text": "anterior", "start": 217, "end": 225, "id": 37}, {"text": "mediastinum", "start": 226, "end": 237, "id": 38}, {"text": "in", "start": 238, "end": 240, "id": 39}, {"text": "PET", "start": 241, "end": 244, "id": 40}, {"text": "scan", "start": 245, "end": 249, "id": 41}, {"text": "(", "start": 250, "end": 251, "id": 42}, {"text": "maximum", "start": 251, "end": 258, "id": 43}, {"text": "standardized", "start": 259, "end": 271, "id": 44}, {"text": "uptake", "start": 272, "end": 278, "id": 45}, {"text": "value", "start": 279, "end": 284, "id": 46}, {"text": "(", "start": 285, "end": 286, "id": 47}, {"text": "SUVmax", "start": 286, "end": 292, "id": 48}, {"text": ")", "start": 292, "end": 293, "id": 49}, {"text": "early", "start": 294, "end": 299, "id": 50}, {"text": ":", "start": 299, "end": 300, "id": 51}, {"text": "3.5", "start": 301, "end": 304, "id": 52}, {"text": ",", "start": 304, "end": 305, "id": 53}, {"text": "delayed", "start": 306, "end": 313, "id": 54}, {"text": ":", "start": 313, "end": 314, "id": 55}, {"text": "4.2", "start": 315, "end": 318, "id": 56}, {"text": ")", "start": 318, "end": 319, "id": 57}, {"text": ".", "start": 319, "end": 320, "id": 58}]}
{"pdf_hash": "e0f8ec4e1e47fa889e87a7d32f8b33a94a2861b5", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2: Panel A and B show the left anterior oblique (LAO) fluoroscopic view and the three-dimensional electroanatomic imaging respectively with the position of the catheters at the end of the ablation procedure. The red dots represent the radiofrequency applications around the pulmonary veins, and through the cavotricuspid isthmus (three-dimensional red dots). A quadripolar catheter is placed in the coronary sinus, a multipolar catheter along the lateral right atrium and the ablation catheter (white arrow) in the cavotricuspid isthmus. Panel C shows the occlusion of the posterolateral branch of the RCA (black arrow). 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{"pdf_hash": "373c0994bb0000443963f73954c28e75a29ca070", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1 Image A shows the bolt (crossbow arrow) entering the patient\u2019s right breast and chest. Image B is the chest X-ray taken in the trauma bay showing the transmediastinal trajectory and partial visualization of the tip of the bolt with a field point. Image C demonstrates the tip of the bolt after removal.", "width": 970, "height": 306, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "c": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "57191daa-0339-4793-a9df-0581a3126162", "label": "a", "points": [[33.4, -0.3], [33.4, 269.5], [338.3, 269.5], [338.3, -0.3]], "color": "yellow"}, {"id": "cc4b921f-6ba8-4408-a379-5beef9c440e3", "label": "b", "points": [[342.9, 5.9], [342.9, 274], [664.7, 274], [664.7, 5.9]], "color": "cyan"}, {"id": "04aa9f13-a67b-4834-85a8-cec5107a6367", "label": "c", "points": [[670.9, 2.8], [670.9, 269.5], [936, 269.5], [936, 2.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Image", "start": 9, "end": 14, "id": 2}, {"text": "A", "start": 15, "end": 16, "id": 3}, {"text": "shows", "start": 17, "end": 22, "id": 4}, {"text": "the", "start": 23, "end": 26, "id": 5}, {"text": "bolt", "start": 27, "end": 31, "id": 6}, {"text": "(", "start": 32, "end": 33, "id": 7}, {"text": "crossbow", "start": 33, "end": 41, "id": 8}, {"text": "arrow", "start": 42, "end": 47, "id": 9}, {"text": ")", "start": 47, "end": 48, "id": 10}, {"text": "entering", "start": 49, "end": 57, "id": 11}, {"text": "the", "start": 58, "end": 61, "id": 12}, {"text": "patient", "start": 62, "end": 69, "id": 13}, {"text": "\u2019s", "start": 69, "end": 71, "id": 14}, {"text": "right", "start": 72, "end": 77, "id": 15}, {"text": "breast", "start": 78, "end": 84, "id": 16}, {"text": "and", "start": 85, "end": 88, "id": 17}, {"text": "chest", "start": 89, "end": 94, "id": 18}, {"text": ".", "start": 94, "end": 95, "id": 19}, {"text": "Image", "start": 96, "end": 101, "id": 20}, {"text": "B", "start": 102, "end": 103, "id": 21}, {"text": "is", "start": 104, "end": 106, "id": 22}, {"text": "the", "start": 107, "end": 110, "id": 23}, {"text": "chest", "start": 111, "end": 116, "id": 24}, {"text": "X", "start": 117, "end": 118, "id": 25}, {"text": "-", "start": 118, "end": 119, "id": 26}, {"text": "ray", "start": 119, "end": 122, "id": 27}, {"text": "taken", "start": 123, "end": 128, "id": 28}, {"text": "in", "start": 129, "end": 131, "id": 29}, {"text": "the", "start": 132, "end": 135, "id": 30}, {"text": "trauma", "start": 136, "end": 142, "id": 31}, {"text": "bay", "start": 143, "end": 146, "id": 32}, {"text": "showing", "start": 147, "end": 154, "id": 33}, {"text": "the", "start": 155, "end": 158, "id": 34}, {"text": "transmediastinal", "start": 159, "end": 175, "id": 35}, {"text": "trajectory", "start": 176, "end": 186, "id": 36}, {"text": "and", "start": 187, "end": 190, "id": 37}, {"text": "partial", "start": 191, "end": 198, "id": 38}, {"text": "visualization", "start": 199, "end": 212, "id": 39}, {"text": "of", "start": 213, "end": 215, "id": 40}, {"text": "the", "start": 216, "end": 219, "id": 41}, {"text": "tip", "start": 220, "end": 223, "id": 42}, {"text": "of", "start": 224, "end": 226, "id": 43}, {"text": "the", "start": 227, "end": 230, "id": 44}, {"text": "bolt", "start": 231, "end": 235, "id": 45}, {"text": "with", "start": 236, "end": 240, "id": 46}, {"text": "a", "start": 241, "end": 242, "id": 47}, {"text": "field", "start": 243, "end": 248, "id": 48}, {"text": "point", "start": 249, "end": 254, "id": 49}, {"text": ".", "start": 254, "end": 255, "id": 50}, {"text": "Image", "start": 256, "end": 261, "id": 51}, {"text": "C", "start": 262, "end": 263, "id": 52}, {"text": "demonstrates", "start": 264, "end": 276, "id": 53}, {"text": "the", "start": 277, "end": 280, "id": 54}, {"text": "tip", "start": 281, "end": 284, "id": 55}, {"text": "of", "start": 285, "end": 287, "id": 56}, {"text": "the", "start": 288, "end": 291, "id": 57}, {"text": "bolt", "start": 292, "end": 296, "id": 58}, {"text": "after", "start": 297, "end": 302, "id": 59}, {"text": "removal", "start": 303, "end": 310, "id": 60}, {"text": ".", "start": 310, "end": 311, "id": 61}]}
{"pdf_hash": "1ef3ff4e1012612c3a09f1ce5573e5b7cf619ae7", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Fig. 6 Acute infectious cystitis with mural bladder abscess in an 89-year-old man with acute urinary retention, fever, leukocytosis and impaired renal function. Unenhanced MRI including MR pyelographic (a) and axial fat-suppressed (b) images revealed bilateral hydronephrosis, contracted bladder and prominent inflammatory changes (+) in the surrounding extraperitoneal fat planes. Additionally, sagittal T2weighted image (c) showed a focal thickening (arrows) at the bladder dome, with intramural fluid collection (arrowhead). 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{"pdf_hash": "c98a2c5ff4afa38ba718c50522c54e0658f0afab", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. A. Nasal cavity width is made on axial images. B. Boundary lines are drawn surrounding the sinus cavity in the axial, coronal, and sagittal views individually to help assist with the maxillary sinus volume measurement.", "width": 1224, "height": 434, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13], "b": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "80138f0b-c86e-4df4-ac52-bad23ba2993f", "label": "a", "points": [[1.9, 0], [1.9, 431.2], [568.5, 431.2], [568.5, 0]], "color": "yellow"}, {"id": "2e87c06a-8fb7-490d-8484-bcd63bd22913", "label": "b", "points": [[580.1, 3.9], [580.1, 433.2], [1220.2, 433.2], [1220.2, 3.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A.", "start": 8, "end": 10, "id": 4}, {"text": "Nasal", "start": 11, "end": 16, "id": 5}, {"text": "cavity", "start": 17, "end": 23, "id": 6}, {"text": "width", "start": 24, "end": 29, "id": 7}, {"text": "is", "start": 30, "end": 32, "id": 8}, {"text": "made", "start": 33, "end": 37, "id": 9}, {"text": "on", "start": 38, "end": 40, "id": 10}, {"text": "axial", "start": 41, "end": 46, "id": 11}, {"text": "images", "start": 47, "end": 53, "id": 12}, {"text": ".", "start": 53, "end": 54, "id": 13}, {"text": "B.", "start": 55, "end": 57, "id": 14}, {"text": "Boundary", "start": 58, "end": 66, "id": 15}, {"text": "lines", "start": 67, "end": 72, "id": 16}, {"text": "are", "start": 73, "end": 76, "id": 17}, {"text": "drawn", "start": 77, "end": 82, "id": 18}, {"text": "surrounding", "start": 83, "end": 94, "id": 19}, {"text": "the", "start": 95, "end": 98, "id": 20}, {"text": "sinus", "start": 99, "end": 104, "id": 21}, {"text": "cavity", "start": 105, "end": 111, "id": 22}, {"text": "in", "start": 112, "end": 114, "id": 23}, {"text": "the", "start": 115, "end": 118, "id": 24}, {"text": "axial", "start": 119, "end": 124, "id": 25}, {"text": ",", "start": 124, "end": 125, "id": 26}, {"text": "coronal", "start": 126, "end": 133, "id": 27}, {"text": ",", "start": 133, "end": 134, "id": 28}, {"text": "and", "start": 135, "end": 138, "id": 29}, {"text": "sagittal", "start": 139, "end": 147, "id": 30}, {"text": "views", "start": 148, "end": 153, "id": 31}, {"text": "individually", "start": 154, "end": 166, "id": 32}, {"text": "to", "start": 167, "end": 169, "id": 33}, {"text": "help", "start": 170, "end": 174, "id": 34}, {"text": "assist", "start": 175, "end": 181, "id": 35}, {"text": "with", "start": 182, "end": 186, "id": 36}, {"text": "the", "start": 187, "end": 190, "id": 37}, {"text": "maxillary", "start": 191, "end": 200, "id": 38}, {"text": "sinus", "start": 201, "end": 206, "id": 39}, {"text": "volume", "start": 207, "end": 213, "id": 40}, {"text": "measurement", "start": 214, "end": 225, "id": 41}, {"text": ".", "start": 225, "end": 226, "id": 42}]}
{"pdf_hash": "9a257eea40e6c5ba48393618ac67f9308bc17525", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2 Transabdominal ultrasound image of patient. A: Active extensive ulcerative colitis. The wall of the transverse colon is widened (largest diameter: 12 mm) and the lumen is narrowed; B: Stricturing ileocolonic Crohn\u2019s disease. Thirty-three millimeter long fibrotic stenosis at the end of the terminal ileum.", "width": 1276, "height": 394, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "e983cf5d-f63e-4ce8-ba70-0dce18f2561e", "label": "a", "points": [[8.4, 2.7], [8.4, 391.8], [623.3, 391.8], [623.3, 2.7]], "color": "yellow"}, {"id": "cfe98e7b-4c67-4e28-b311-8e5617cf53ea", "label": "b", "points": [[637.4, 0.7], [637.4, 391.8], [1266.4, 391.8], [1266.4, 0.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Transabdominal", "start": 9, "end": 23, "id": 2}, {"text": "ultrasound", "start": 24, "end": 34, "id": 3}, {"text": "image", "start": 35, "end": 40, "id": 4}, {"text": "of", "start": 41, "end": 43, "id": 5}, {"text": "patient", "start": 44, "end": 51, "id": 6}, {"text": ".", "start": 51, "end": 52, "id": 7}, {"text": "A", "start": 53, "end": 54, "id": 8}, {"text": ":", "start": 54, "end": 55, "id": 9}, {"text": "Active", "start": 56, "end": 62, "id": 10}, {"text": "extensive", "start": 63, "end": 72, "id": 11}, {"text": "ulcerative", "start": 73, "end": 83, "id": 12}, {"text": "colitis", "start": 84, "end": 91, "id": 13}, {"text": ".", "start": 91, "end": 92, "id": 14}, {"text": "The", "start": 93, "end": 96, "id": 15}, {"text": "wall", "start": 97, "end": 101, "id": 16}, {"text": "of", "start": 102, "end": 104, "id": 17}, {"text": "the", "start": 105, "end": 108, "id": 18}, {"text": "transverse", "start": 109, "end": 119, "id": 19}, {"text": "colon", "start": 120, "end": 125, "id": 20}, {"text": "is", "start": 126, "end": 128, "id": 21}, {"text": "widened", "start": 129, "end": 136, "id": 22}, {"text": "(", "start": 137, "end": 138, "id": 23}, {"text": "largest", "start": 138, "end": 145, "id": 24}, {"text": "diameter", "start": 146, "end": 154, "id": 25}, {"text": ":", "start": 154, "end": 155, "id": 26}, {"text": "12", "start": 156, "end": 158, "id": 27}, {"text": "mm", "start": 159, "end": 161, "id": 28}, {"text": ")", "start": 161, "end": 162, "id": 29}, {"text": "and", "start": 163, "end": 166, "id": 30}, {"text": "the", "start": 167, "end": 170, "id": 31}, {"text": "lumen", "start": 171, "end": 176, "id": 32}, {"text": "is", "start": 177, "end": 179, "id": 33}, {"text": "narrowed", "start": 180, "end": 188, "id": 34}, {"text": ";", "start": 188, "end": 189, "id": 35}, {"text": "B", "start": 190, "end": 191, "id": 36}, {"text": ":", "start": 191, "end": 192, "id": 37}, {"text": "Stricturing", "start": 193, "end": 204, "id": 38}, {"text": "ileocolonic", "start": 205, "end": 216, "id": 39}, {"text": "Crohn", "start": 217, "end": 222, "id": 40}, {"text": "\u2019s", "start": 222, "end": 224, "id": 41}, {"text": "disease", "start": 225, "end": 232, "id": 42}, {"text": ".", "start": 232, "end": 233, "id": 43}, {"text": "Thirty", "start": 234, "end": 240, "id": 44}, {"text": "-", "start": 240, "end": 241, "id": 45}, {"text": "three", "start": 241, "end": 246, "id": 46}, {"text": "millimeter", "start": 247, "end": 257, "id": 47}, {"text": "long", "start": 258, "end": 262, "id": 48}, {"text": "fibrotic", "start": 263, "end": 271, "id": 49}, {"text": "stenosis", "start": 272, "end": 280, "id": 50}, {"text": "at", "start": 281, "end": 283, "id": 51}, {"text": "the", "start": 284, "end": 287, "id": 52}, {"text": "end", "start": 288, "end": 291, "id": 53}, {"text": "of", "start": 292, "end": 294, "id": 54}, {"text": "the", "start": 295, "end": 298, "id": 55}, {"text": "terminal", "start": 299, "end": 307, "id": 56}, {"text": "ileum", "start": 308, "end": 313, "id": 57}, {"text": ".", "start": 313, "end": 314, "id": 58}]}
{"pdf_hash": "3d2b9b754662c4714386e9ae859a6ca4d9d4da65", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 (a) Preoperative radiograph of patient 8. (b) Postoperative radiograph of patient 8 after spondylodesis with the Spine\u00aex-system", "width": 1340, "height": 1158, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10], "b": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27]}, "subfigures": [{"id": "f7a5d41e-45b3-4727-916b-d167bd59467a", "label": "a", "points": [[16, 25.1], [16, 1144.8], [636.2, 1144.8], [636.2, 25.1]], "color": "yellow"}, {"id": "4981212f-6a92-448e-8e84-2b206b1d630b", "label": "b", "points": [[706, 42], [706, 1058], [1324.1, 1058], [1324.1, 42]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Preoperative", "start": 13, "end": 25, "id": 5}, {"text": "radiograph", "start": 26, "end": 36, "id": 6}, {"text": "of", "start": 37, "end": 39, "id": 7}, {"text": "patient", "start": 40, "end": 47, "id": 8}, {"text": "8", "start": 48, "end": 49, "id": 9}, {"text": ".", "start": 49, "end": 50, "id": 10}, {"text": "(", "start": 51, "end": 52, "id": 11}, {"text": "b", "start": 52, "end": 53, "id": 12}, {"text": ")", "start": 53, "end": 54, "id": 13}, {"text": "Postoperative", "start": 55, "end": 68, "id": 14}, {"text": "radiograph", "start": 69, "end": 79, "id": 15}, {"text": "of", "start": 80, "end": 82, "id": 16}, {"text": "patient", "start": 83, "end": 90, "id": 17}, {"text": "8", "start": 91, "end": 92, "id": 18}, {"text": "after", "start": 93, "end": 98, "id": 19}, {"text": "spondylodesis", "start": 99, "end": 112, "id": 20}, {"text": "with", "start": 113, "end": 117, "id": 21}, {"text": "the", "start": 118, "end": 121, "id": 22}, {"text": "Spine", "start": 122, "end": 127, "id": 23}, {"text": "\u00ae", "start": 127, "end": 128, "id": 24}, {"text": "x", "start": 128, "end": 129, "id": 25}, {"text": "-", "start": 129, "end": 130, "id": 26}, {"text": "system", "start": 130, "end": 136, "id": 27}]}
{"pdf_hash": "f1303c63e59d1b23c5417da41f7c136bb5d19be7", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. Endoscopic findings of type 1 posterior urethral valves (PUVs) (A, B) and type 3 PUV (C). Valve like structure (A), membrane like structure (B), and so called \u201cCobb\u2019s collar\u201d seen in type 3 PUV (C). Dotted line depicts margin of the lesion.", "width": 1382, "height": 486, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 27, 28, 29, 30, 31, 32, 33], "b": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 35, 36, 37, 38, 39, 40], "c": [4, 5, 6, 21, 22, 23, 24, 25, 26, 27, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "6872c8d0-36d9-4183-adbd-37938a9a39fe", "label": "a", "points": [[4.4, 0], [4.4, 462.9], [465.1, 462.9], [465.1, 0]], "color": "yellow"}, {"id": "cc892e05-6dab-49b6-badf-887e76d8240c", "label": "b", "points": [[473.8, 4.4], [473.8, 460.7], [921.4, 460.7], [921.4, 4.4]], "color": "cyan"}, {"id": "b1c9f43a-c4f2-4778-9833-3576b72ca372", "label": "c", "points": [[932.3, 4.4], [932.3, 449.8], [1375.5, 449.8], [1375.5, 4.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Endoscopic", "start": 8, "end": 18, "id": 4}, {"text": "findings", "start": 19, "end": 27, "id": 5}, {"text": "of", "start": 28, "end": 30, "id": 6}, {"text": "type", "start": 31, "end": 35, "id": 7}, {"text": "1", "start": 36, "end": 37, "id": 8}, {"text": "posterior", "start": 38, "end": 47, "id": 9}, {"text": "urethral", "start": 48, "end": 56, "id": 10}, {"text": "valves", "start": 57, "end": 63, "id": 11}, {"text": "(", "start": 64, "end": 65, "id": 12}, {"text": "PUVs", "start": 65, "end": 69, "id": 13}, {"text": ")", "start": 69, "end": 70, "id": 14}, {"text": "(", "start": 71, "end": 72, "id": 15}, {"text": "A", "start": 72, "end": 73, "id": 16}, {"text": ",", "start": 73, "end": 74, "id": 17}, {"text": "B", "start": 75, "end": 76, "id": 18}, {"text": ")", "start": 76, "end": 77, "id": 19}, {"text": "and", "start": 78, "end": 81, "id": 20}, {"text": "type", "start": 82, "end": 86, "id": 21}, {"text": "3", "start": 87, "end": 88, "id": 22}, {"text": "PUV", "start": 89, "end": 92, "id": 23}, {"text": "(", "start": 93, "end": 94, "id": 24}, {"text": "C", "start": 94, "end": 95, "id": 25}, {"text": ")", "start": 95, "end": 96, "id": 26}, {"text": ".", "start": 96, "end": 97, "id": 27}, {"text": "Valve", "start": 98, "end": 103, "id": 28}, {"text": "like", "start": 104, "end": 108, "id": 29}, {"text": "structure", "start": 109, "end": 118, "id": 30}, {"text": "(", "start": 119, "end": 120, "id": 31}, {"text": "A", "start": 120, "end": 121, "id": 32}, {"text": ")", "start": 121, "end": 122, "id": 33}, {"text": ",", "start": 122, "end": 123, "id": 34}, {"text": "membrane", "start": 124, "end": 132, "id": 35}, {"text": "like", "start": 133, "end": 137, "id": 36}, {"text": "structure", "start": 138, "end": 147, "id": 37}, {"text": "(", "start": 148, "end": 149, "id": 38}, {"text": "B", "start": 149, "end": 150, "id": 39}, {"text": ")", "start": 150, "end": 151, "id": 40}, {"text": ",", "start": 151, "end": 152, "id": 41}, {"text": "and", "start": 153, "end": 156, "id": 42}, {"text": "so", "start": 157, "end": 159, "id": 43}, {"text": "called", "start": 160, "end": 166, "id": 44}, {"text": "\u201c", "start": 167, "end": 168, "id": 45}, {"text": "Cobb", "start": 168, "end": 172, "id": 46}, {"text": "\u2019s", "start": 172, "end": 174, "id": 47}, {"text": "collar", "start": 175, "end": 181, "id": 48}, {"text": "\u201d", "start": 181, "end": 182, "id": 49}, {"text": "seen", "start": 183, "end": 187, "id": 50}, {"text": "in", "start": 188, "end": 190, "id": 51}, {"text": "type", "start": 191, "end": 195, "id": 52}, {"text": "3", "start": 196, "end": 197, "id": 53}, {"text": "PUV", "start": 198, "end": 201, "id": 54}, {"text": "(", "start": 202, "end": 203, "id": 55}, {"text": "C", "start": 203, "end": 204, "id": 56}, {"text": ")", "start": 204, "end": 205, "id": 57}, {"text": ".", "start": 205, "end": 206, "id": 58}, {"text": "Dotted", "start": 207, "end": 213, "id": 59}, {"text": "line", "start": 214, "end": 218, "id": 60}, {"text": "depicts", "start": 219, "end": 226, "id": 61}, {"text": "margin", "start": 227, "end": 233, "id": 62}, {"text": "of", "start": 234, "end": 236, "id": 63}, {"text": "the", "start": 237, "end": 240, "id": 64}, {"text": "lesion", "start": 241, "end": 247, "id": 65}, {"text": ".", "start": 247, "end": 248, "id": 66}]}
{"pdf_hash": "45e1ac07441f9bfb362c404eeb4adab527d06fd4", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Fig. 2 Radiographs of 75-year-old man with osteonecrosis of left femoral head. a Preoperative radiograph of left hip demonstrates collapse of left femoral head (Ficat stage IV) and Dorr type C bone. b Postoperative radiograph of left hip obtained nine years after surgery demonstrates that Proxima stem is rigidly fixed in a satisfactory position in left hip", "width": 582, "height": 994, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "32a737ea-90c2-4177-98ff-87b9061c5741", "label": "a", "points": [[37.7, 32.3], [37.7, 453.3], [554.7, 453.3], [554.7, 32.3]], "color": "yellow"}, {"id": "08c44f09-09a6-4d24-9e44-e76bdf33badc", "label": "b", "points": [[37.7, 461], [37.7, 971], [543.7, 971], [543.7, 461]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Radiographs", "start": 7, "end": 18, "id": 3}, {"text": "of", "start": 19, "end": 21, "id": 4}, {"text": "75-year", "start": 22, "end": 29, "id": 5}, {"text": "-", "start": 29, "end": 30, "id": 6}, {"text": "old", "start": 30, "end": 33, "id": 7}, {"text": "man", "start": 34, "end": 37, "id": 8}, {"text": "with", "start": 38, "end": 42, "id": 9}, {"text": "osteonecrosis", "start": 43, "end": 56, "id": 10}, {"text": "of", "start": 57, "end": 59, "id": 11}, {"text": "left", "start": 60, "end": 64, "id": 12}, {"text": "femoral", "start": 65, "end": 72, "id": 13}, {"text": "head", "start": 73, "end": 77, "id": 14}, {"text": ".", "start": 77, "end": 78, "id": 15}, {"text": "a", "start": 79, "end": 80, "id": 16}, {"text": "Preoperative", "start": 81, "end": 93, "id": 17}, {"text": "radiograph", "start": 94, "end": 104, "id": 18}, {"text": "of", "start": 105, "end": 107, "id": 19}, {"text": "left", "start": 108, "end": 112, "id": 20}, {"text": "hip", "start": 113, "end": 116, "id": 21}, {"text": "demonstrates", "start": 117, "end": 129, "id": 22}, {"text": "collapse", "start": 130, "end": 138, "id": 23}, {"text": "of", "start": 139, "end": 141, "id": 24}, {"text": "left", "start": 142, "end": 146, "id": 25}, {"text": "femoral", "start": 147, "end": 154, "id": 26}, {"text": "head", "start": 155, "end": 159, "id": 27}, {"text": "(", "start": 160, "end": 161, "id": 28}, {"text": "Ficat", "start": 161, "end": 166, "id": 29}, {"text": "stage", "start": 167, "end": 172, "id": 30}, {"text": "IV", "start": 173, "end": 175, "id": 31}, {"text": ")", "start": 175, "end": 176, "id": 32}, {"text": "and", "start": 177, "end": 180, "id": 33}, {"text": "Dorr", "start": 181, "end": 185, "id": 34}, {"text": "type", "start": 186, "end": 190, "id": 35}, {"text": "C", "start": 191, "end": 192, "id": 36}, {"text": "bone", "start": 193, "end": 197, "id": 37}, {"text": ".", "start": 197, "end": 198, "id": 38}, {"text": "b", "start": 199, "end": 200, "id": 39}, {"text": "Postoperative", "start": 201, "end": 214, "id": 40}, {"text": "radiograph", "start": 215, "end": 225, "id": 41}, {"text": "of", "start": 226, "end": 228, "id": 42}, {"text": "left", "start": 229, "end": 233, "id": 43}, {"text": "hip", "start": 234, "end": 237, "id": 44}, {"text": "obtained", "start": 238, "end": 246, "id": 45}, {"text": "nine", "start": 247, "end": 251, "id": 46}, {"text": "years", "start": 252, "end": 257, "id": 47}, {"text": "after", "start": 258, "end": 263, "id": 48}, {"text": "surgery", "start": 264, "end": 271, "id": 49}, {"text": "demonstrates", "start": 272, "end": 284, "id": 50}, {"text": "that", "start": 285, "end": 289, "id": 51}, {"text": "Proxima", "start": 290, "end": 297, "id": 52}, {"text": "stem", "start": 298, "end": 302, "id": 53}, {"text": "is", "start": 303, "end": 305, "id": 54}, {"text": "rigidly", "start": 306, "end": 313, "id": 55}, {"text": "fixed", "start": 314, "end": 319, "id": 56}, {"text": "in", "start": 320, "end": 322, "id": 57}, {"text": "a", "start": 323, "end": 324, "id": 58}, {"text": "satisfactory", "start": 325, "end": 337, "id": 59}, {"text": "position", "start": 338, "end": 346, "id": 60}, {"text": "in", "start": 347, "end": 349, "id": 61}, {"text": "left", "start": 350, "end": 354, "id": 62}, {"text": "hip", "start": 355, "end": 358, "id": 63}]}
{"pdf_hash": "8065682f8ccec5d08202733629f107e7f4446476", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Imaging features of clinical findings in central serous chorioretinopathy (CSCR) on multicolor imaging (MCI) and fundus autofluorescence (FAF) -Clinical findings on MCI (left) and their corresponding FAF images (right) are noted. A discrete patch of retinal pigment epithelium (RPE) atrophy is noted nasal to the macula in the top left and right images which is seen as an area with visible choroidal vasculature surrounded by altered reflectance on MCI and as a hypoautofluorescent area surrounding a central hyperautofluorescene on FAF. Focal dark green lesions noted superior and temporal to macula on MCI (bottom left) and the corresponding areas of focal hyperautofluorescence on FAF (bottom right) depict pigment epithelial detachments.", "width": 1098, "height": 824, "subcaptions": {"a": [27, 28, 29, 30, 31, 32, 33, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84], "b": [27, 28, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 67, 68, 69, 70, 71, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96], "c": [27, 28, 29, 30, 31, 32, 33, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112], "d": [128, 129, 130, 27, 28, 36, 37, 38, 39, 40, 41, 42, 43, 44, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "ea3d8af1-ebc8-4f53-9450-4d063b0fa1f9", "label": "a", "points": [[10.5, 7.7], [10.5, 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{"pdf_hash": "783c8da527455037a4e6aed8864694d6d289468f", "fig_key": "Figure4", "fig_uri": "13-Figure4-1.png", "text": "Figure 4. Multimodal imaging of the left eye of a 71 year-old female with multiple soft drusen seen in the ophthalmoscopic examination. A. The red-free photograph shows a druse that is seen in greater detail in (B) the adaptive optics (AO) image. The cone density showed a modest reduction over conventional drusen as compared with between them. D. 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{"pdf_hash": "84461e7e16f1febd67517eeee4a68e6e600fce81", "fig_key": "Figure8", "fig_uri": "6-Figure8-1.png", "text": "Fig. 8. 43-year-old man with branch duct type intraductal papillary mucinous neoplasm manifesting as multilocular cystic lesion (pleomorphic cystic). A. Contrast enhanced CT image during venous phase shows multilocular pleomorphic cystic lesion in head of pancreas. B. Note dilated downstream pancreatic duct (black arrow). C. Gross specimen showing ill-defined multilocular cystic tumor in head of pancreas (black arrow) which contained mucinous material. 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{"pdf_hash": "b9932fdd02f5e3121657de9f646b1d4917ddf745", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Adult phenotype and Raldh2 protein analysis in Raldh2L\u2013/\u2013 mutants. (A,B) Ventral (left) and profile (right) views of the forepaws of 2- month-old mice. Note the abnormal flexure of anterior digits (bracket) and partial fusion between digits 2, 3 and 4 (arrowheads). (C,J) Immunodetection of Raldh2 on whole-mount embryos (C,D), transverse sections at the level of the brachial spinal cord (E-H) and dissected spinal cords flattened into an \u2018open book\u2019 configuration (I,J). 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{"pdf_hash": "f7a49de3430f9f3bd410f7984ec1face6c9d5782", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. (A) SPM{t} map thresholded at FDR P \\ 0.05 for choose versus specified rule trials in experiment 1, averaging across color and height modalities and types of second cue (see Table 1) (B) SPM{t} map thresholded at FDR P \\ 0.05 for action-selection versus specification in experiment 1 (choose action vs. specified action trials in Table 1) (C) SPM{t} emphasizing that rule-selection in (A) and action-selection in (B) did not differ from each other by t-tests at either FDR P \\ 0.05 or at the liberal threshold of P \\ 0.01 uncorrected. (D) SPM{t} at uncorrected threshold P \\ 0.001 for rule-selection versus specification from experiment 2, averaging across all types of second cue (see Table 1). Correction to P \\ 0.05 within a frontal ROI is indicated in Table 2. (E) SPM{t} FDR P \\ 0.05 for action-selection versus specification from experiment 3 (cf. choose action vs. specified action trials in Table 1) (F) SPM{t} FDR P \\ 0.05 for the application of a current rule to the selection among 2 or 4 targets versus a single target in experiment 1 (apply rule vs. irrelevant to specified response in Table 1). Note the absence of prefrontal cortical activations in comparison to free-selection of actions in (B). The SPM{t}s are rendered on the SPM5 canonical T 1 brain volume in MNI space. Yellow lines are overlaid to assist comparison of the dorsal-and ventral-prefrontal activations in (A), (B), (D), and (E). 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{"pdf_hash": "5a872723fe2838877c7dd442d07877e23db1a325", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. First left maxillary molar (CEM case); A) Initial radiograph; B) Postoperative radiograph; C) Seven months recall with SS Crown; D) 18 months recall", "width": 1418, "height": 310, "subcaptions": {"a": [12, 13, 14, 15], "b": [17, 18, 19, 20], "c": [22, 23, 24, 25, 26, 27, 28, 29], "d": [31, 32, 33, 34, 35]}, "subfigures": [{"id": "60b038b5-5265-4754-96b3-c925f01c9f1e", "label": "a", "points": [[10.2, 4.1], [10.2, 264], [344, 264], [344, 4.1]], "color": "yellow"}, {"id": "d49913c8-d324-40b6-8ef5-fdbde765ae9a", "label": "b", "points": [[352.9, 6.4], [352.9, 272.9], [718.1, 272.9], [718.1, 6.4]], "color": "cyan"}, {"id": "b7abb4d8-f12f-434e-b46e-a7fc0cfedb3c", "label": "c", "points": [[731.5, 4.1], [731.5, 272.9], [1029.5, 272.9], [1029.5, 4.1]], "color": "magenta"}, {"id": "20ca381a-a502-49d8-baa6-5e69df7b6c43", "label": "d", "points": [[1047.4, 8.6], [1047.4, 277.4], [1410.3, 277.4], [1410.3, 8.6]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "First", "start": 10, "end": 15, "id": 3}, {"text": "left", "start": 16, "end": 20, "id": 4}, {"text": "maxillary", "start": 21, "end": 30, "id": 5}, {"text": "molar", "start": 31, "end": 36, "id": 6}, {"text": "(", "start": 37, "end": 38, "id": 7}, {"text": "CEM", "start": 38, "end": 41, "id": 8}, {"text": "case", "start": 42, "end": 46, "id": 9}, {"text": ")", "start": 46, "end": 47, "id": 10}, {"text": ";", "start": 47, "end": 48, "id": 11}, {"text": "A", "start": 49, "end": 50, "id": 12}, {"text": ")", "start": 50, "end": 51, "id": 13}, {"text": "Initial", "start": 52, "end": 59, "id": 14}, {"text": "radiograph", "start": 60, "end": 70, "id": 15}, {"text": ";", "start": 70, "end": 71, "id": 16}, {"text": "B", "start": 72, "end": 73, "id": 17}, {"text": ")", "start": 73, "end": 74, "id": 18}, {"text": "Postoperative", "start": 75, "end": 88, "id": 19}, {"text": "radiograph", "start": 89, "end": 99, "id": 20}, {"text": ";", "start": 99, "end": 100, "id": 21}, {"text": "C", "start": 101, "end": 102, "id": 22}, {"text": ")", "start": 102, "end": 103, "id": 23}, {"text": "Seven", "start": 104, "end": 109, "id": 24}, {"text": "months", "start": 110, "end": 116, "id": 25}, {"text": "recall", "start": 117, "end": 123, "id": 26}, {"text": "with", "start": 124, "end": 128, "id": 27}, {"text": "SS", "start": 129, "end": 131, "id": 28}, {"text": "Crown", "start": 132, "end": 137, "id": 29}, {"text": ";", "start": 137, "end": 138, "id": 30}, {"text": "D", "start": 139, "end": 140, "id": 31}, {"text": ")", "start": 140, "end": 141, "id": 32}, {"text": "18", "start": 142, "end": 144, "id": 33}, {"text": "months", "start": 145, "end": 151, "id": 34}, {"text": "recall", "start": 152, "end": 158, "id": 35}]}
{"pdf_hash": "f43bc13b95ebdf9489f92f19ee5f4e4ef83c1dbf", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig 2. Radiograph of the hands. A, Soft tissue swelling along with periarticular calcifications at both 1st carpometacarpal joints. There is no digital calcification. B, Calcification in the region of the triangular cartilage on the left and adjacent to the triquetrum and ulnar styloid process of the left hand.", "width": 996, "height": 384, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "f6c62faa-f4aa-404b-81fa-097df3615d87", "label": "a", "points": [[3.9, 3.1], [3.9, 357.2], [568.8, 357.2], [568.8, 3.1]], "color": "yellow"}, {"id": "e3a1cfc3-5a2f-4c98-aa6b-6edb08958ad7", "label": "b", "points": [[586.1, 1.6], [586.1, 350.9], [992.1, 350.9], [992.1, 1.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Radiograph", "start": 7, "end": 17, "id": 3}, {"text": "of", "start": 18, "end": 20, "id": 4}, {"text": "the", "start": 21, "end": 24, "id": 5}, {"text": "hands", "start": 25, "end": 30, "id": 6}, {"text": ".", "start": 30, "end": 31, "id": 7}, {"text": "A", "start": 32, "end": 33, "id": 8}, {"text": ",", "start": 33, "end": 34, "id": 9}, {"text": "Soft", "start": 35, "end": 39, "id": 10}, {"text": "tissue", "start": 40, "end": 46, "id": 11}, {"text": "swelling", "start": 47, "end": 55, "id": 12}, {"text": "along", "start": 56, "end": 61, "id": 13}, {"text": "with", "start": 62, "end": 66, "id": 14}, {"text": "periarticular", "start": 67, "end": 80, "id": 15}, {"text": "calcifications", "start": 81, "end": 95, "id": 16}, {"text": "at", "start": 96, "end": 98, "id": 17}, {"text": "both", "start": 99, "end": 103, "id": 18}, {"text": "1st", "start": 104, "end": 107, "id": 19}, {"text": "carpometacarpal", "start": 108, "end": 123, "id": 20}, {"text": "joints", "start": 124, "end": 130, "id": 21}, {"text": ".", "start": 130, "end": 131, "id": 22}, {"text": "There", "start": 132, "end": 137, "id": 23}, {"text": "is", "start": 138, "end": 140, "id": 24}, {"text": "no", "start": 141, "end": 143, "id": 25}, {"text": "digital", "start": 144, "end": 151, "id": 26}, {"text": "calcification", "start": 152, "end": 165, "id": 27}, {"text": ".", "start": 165, "end": 166, "id": 28}, {"text": "B", "start": 167, "end": 168, "id": 29}, {"text": ",", "start": 168, "end": 169, "id": 30}, {"text": "Calcification", "start": 170, "end": 183, "id": 31}, {"text": "in", "start": 184, "end": 186, "id": 32}, {"text": "the", "start": 187, "end": 190, "id": 33}, {"text": "region", "start": 191, "end": 197, "id": 34}, {"text": "of", "start": 198, "end": 200, "id": 35}, {"text": "the", "start": 201, "end": 204, "id": 36}, {"text": "triangular", "start": 205, "end": 215, "id": 37}, {"text": "cartilage", "start": 216, "end": 225, "id": 38}, {"text": "on", "start": 226, "end": 228, "id": 39}, {"text": "the", "start": 229, "end": 232, "id": 40}, {"text": "left", "start": 233, "end": 237, "id": 41}, {"text": "and", "start": 238, "end": 241, "id": 42}, {"text": "adjacent", "start": 242, "end": 250, "id": 43}, {"text": "to", "start": 251, "end": 253, "id": 44}, {"text": "the", "start": 254, "end": 257, "id": 45}, {"text": "triquetrum", "start": 258, "end": 268, "id": 46}, {"text": "and", "start": 269, "end": 272, "id": 47}, {"text": "ulnar", "start": 273, "end": 278, "id": 48}, {"text": "styloid", "start": 279, "end": 286, "id": 49}, {"text": "process", "start": 287, "end": 294, "id": 50}, {"text": "of", "start": 295, "end": 297, "id": 51}, {"text": "the", "start": 298, "end": 301, "id": 52}, {"text": "left", "start": 302, "end": 306, "id": 53}, {"text": "hand", "start": 307, "end": 311, "id": 54}, {"text": ".", "start": 311, "end": 312, "id": 55}]}
{"pdf_hash": "d65b986d32114f3af953039d052b5d595b6a47bb", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4 Third generation angiographic Dual-Source-CT of a three-day old newborn with heterotaxy syndrome and total anomalous pulmonary venous connection. Figure a shows the dextrocardia, AAO = ascending aorta, the circle marks the confluence of the pulmonary veins and the star shows the common pulmonary vein that leads to the innominate vein (triangle). Figure b clearly demonstrates in a left-lateral angulation the confluence of the pulmonary veins (circle), the common pulmonary vein (star), which is centrally obstructed, and the innominate vein (triangle). Using the same symbols figure c demonstrates the spatial relation of anomalous pulmonary venous connection and aorta (AAO = ascending aorta, DAO = descending aorta). The residual ductus arteriosus is marked by an arrow. Figure d shows a modified sagittal section through the heart. 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{"pdf_hash": "894a9ba6a4e78c6970369566a6c2e10293857c77", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig. 3 a\u2013e A 72-year-old male received deep extensor musclepreserving laminoplasty from C4 to C6 levels. Box arrows signify the reattached spinous processes with deep extensor muscles (c). Axial MRI demonstrates preservation of the deep extensor muscles: comparison between preoperative and follow-up scenarios (d and e, respectively)", "width": 1364, "height": 658, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "c": [32, 33, 34, 35, 36, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "d": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49], "e": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 51, 52, 53]}, "subfigures": [{"id": "2a7b173e-92a5-4d5a-af59-a990122571d2", "label": "a", "points": [[2.2, 0], [2.2, 652.9], [323.2, 652.9], [323.2, 0]], "color": "yellow"}, {"id": "581f1ce7-b386-4511-a5ca-8e6bee889768", "label": "a", "points": [[336.2, 4.3], [336.2, 652.9], [659.4, 652.9], [659.4, 4.3]], "color": "cyan"}, {"id": "517140e5-2d28-4f91-bf2b-056b0eace8ce", "label": "c", "points": [[678.8, 8.6], [678.8, 648.6], [1019.2, 648.6], [1019.2, 8.6]], "color": "magenta"}, {"id": "c5b0e42a-18ca-48a9-9bf9-e9ed7ff6cfa3", "label": "d", "points": [[1038.6, 6.5], [1038.6, 340.5], [1355.4, 340.5], [1355.4, 6.5]], "color": "springgreen"}, {"id": "d5951abc-3f81-4d4f-9b63-d19926b38465", "label": "e", "points": [[1040.8, 359.9], [1040.8, 650.8], [1357.5, 650.8], [1357.5, 359.9]], "color": "tomato"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "\u2013", "start": 8, "end": 9, "id": 4}, {"text": "e", "start": 9, "end": 10, "id": 5}, {"text": "A", "start": 11, "end": 12, "id": 6}, {"text": "72-year", "start": 13, "end": 20, "id": 7}, {"text": "-", "start": 20, "end": 21, "id": 8}, {"text": "old", "start": 21, "end": 24, "id": 9}, {"text": "male", "start": 25, "end": 29, "id": 10}, {"text": "received", "start": 30, "end": 38, "id": 11}, {"text": "deep", "start": 39, "end": 43, "id": 12}, {"text": "extensor", "start": 44, "end": 52, "id": 13}, {"text": "musclepreserving", "start": 53, "end": 69, "id": 14}, {"text": "laminoplasty", "start": 70, "end": 82, "id": 15}, {"text": "from", "start": 83, "end": 87, "id": 16}, {"text": "C4", "start": 88, "end": 90, "id": 17}, {"text": "to", "start": 91, "end": 93, "id": 18}, {"text": "C6", "start": 94, "end": 96, "id": 19}, {"text": "levels", "start": 97, "end": 103, "id": 20}, {"text": ".", "start": 103, "end": 104, "id": 21}, {"text": "Box", "start": 105, "end": 108, "id": 22}, {"text": "arrows", "start": 109, "end": 115, "id": 23}, {"text": "signify", "start": 116, "end": 123, "id": 24}, {"text": "the", "start": 124, "end": 127, "id": 25}, {"text": "reattached", "start": 128, "end": 138, "id": 26}, {"text": "spinous", "start": 139, "end": 146, "id": 27}, {"text": "processes", "start": 147, "end": 156, "id": 28}, {"text": "with", "start": 157, "end": 161, "id": 29}, {"text": "deep", "start": 162, "end": 166, "id": 30}, {"text": "extensor", "start": 167, "end": 175, "id": 31}, {"text": "muscles", "start": 176, "end": 183, "id": 32}, {"text": "(", "start": 184, "end": 185, "id": 33}, {"text": "c", "start": 185, "end": 186, "id": 34}, {"text": ")", "start": 186, "end": 187, "id": 35}, {"text": ".", "start": 187, "end": 188, "id": 36}, {"text": "Axial", "start": 189, "end": 194, "id": 37}, {"text": "MRI", "start": 195, "end": 198, "id": 38}, {"text": "demonstrates", "start": 199, "end": 211, "id": 39}, {"text": "preservation", "start": 212, "end": 224, "id": 40}, {"text": "of", "start": 225, "end": 227, "id": 41}, {"text": "the", "start": 228, "end": 231, "id": 42}, {"text": "deep", "start": 232, "end": 236, "id": 43}, {"text": "extensor", "start": 237, "end": 245, "id": 44}, {"text": "muscles", "start": 246, "end": 253, "id": 45}, {"text": ":", "start": 253, "end": 254, "id": 46}, {"text": "comparison", "start": 255, "end": 265, "id": 47}, {"text": "between", "start": 266, "end": 273, "id": 48}, {"text": "preoperative", "start": 274, "end": 286, "id": 49}, {"text": "and", "start": 287, "end": 290, "id": 50}, {"text": "follow", "start": 291, "end": 297, "id": 51}, {"text": "-", "start": 297, "end": 298, "id": 52}, {"text": "up", "start": 298, "end": 300, "id": 53}, {"text": "scenarios", "start": 301, "end": 310, "id": 54}, {"text": "(", "start": 311, "end": 312, "id": 55}, {"text": "d", "start": 312, "end": 313, "id": 56}, {"text": "and", "start": 314, "end": 317, "id": 57}, {"text": "e", "start": 318, "end": 319, "id": 58}, {"text": ",", "start": 319, "end": 320, "id": 59}, {"text": "respectively", "start": 321, "end": 333, "id": 60}, {"text": ")", "start": 333, "end": 334, "id": 61}]}
{"pdf_hash": "6f1307cf8eddf8123545d3fec862d153f5bb9a36", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Pneumo-computed tomography technique. A: The tip of the Foley catheter is lubricated with gel anesthesia; B: The Foley catheter is introduced transorally.", "width": 1038, "height": 846, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "77ad0988-86e9-4b5e-9b41-4e295d507cf6", "label": "a", "points": [[5, 3], [5, 398.2], [392, 398.2], [392, 3]], "color": "yellow"}, {"id": "163460ab-7bc5-4f49-9af7-0e22e29e3806", "label": "b", "points": [[403.4, -0.3], [403.4, 391.6], [788.8, 391.6], [788.8, -0.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Pneumo", "start": 9, "end": 15, "id": 2}, {"text": "-", "start": 15, "end": 16, "id": 3}, {"text": "computed", "start": 16, "end": 24, "id": 4}, {"text": "tomography", "start": 25, "end": 35, "id": 5}, {"text": "technique", "start": 36, "end": 45, "id": 6}, {"text": ".", "start": 45, "end": 46, "id": 7}, {"text": "A", "start": 47, "end": 48, "id": 8}, {"text": ":", "start": 48, "end": 49, "id": 9}, {"text": "The", "start": 50, "end": 53, "id": 10}, {"text": "tip", "start": 54, "end": 57, "id": 11}, {"text": "of", "start": 58, "end": 60, "id": 12}, {"text": "the", "start": 61, "end": 64, "id": 13}, {"text": "Foley", "start": 65, "end": 70, "id": 14}, {"text": "catheter", "start": 71, "end": 79, "id": 15}, {"text": "is", "start": 80, "end": 82, "id": 16}, {"text": "lubricated", "start": 83, "end": 93, "id": 17}, {"text": "with", "start": 94, "end": 98, "id": 18}, {"text": "gel", "start": 99, "end": 102, "id": 19}, {"text": "anesthesia", "start": 103, "end": 113, "id": 20}, {"text": ";", "start": 113, "end": 114, "id": 21}, {"text": "B", "start": 115, "end": 116, "id": 22}, {"text": ":", "start": 116, "end": 117, "id": 23}, {"text": "The", "start": 118, "end": 121, "id": 24}, {"text": "Foley", "start": 122, "end": 127, "id": 25}, {"text": "catheter", "start": 128, "end": 136, "id": 26}, {"text": "is", "start": 137, "end": 139, "id": 27}, {"text": "introduced", "start": 140, "end": 150, "id": 28}, {"text": "transorally", "start": 151, "end": 162, "id": 29}, {"text": ".", "start": 162, "end": 163, "id": 30}]}
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{"pdf_hash": "5f2434814747970c47c4cf55e936976da8b3b21b", "fig_key": "Figure9", "fig_uri": "12-Figure9-1.png", "text": "Fig 9. Radiographs and CT images of P1 and P3 in Group 3. (A) Periapical view of P1 before treatment with an open apex (asterisk). (B) 5-months follow-up radiograph of P1 after the two-mix antibiotics only treatment. (C) 5-month follow-up CT view with completion of apical formation P1. (D) Periapical view of P3 before treatment with an open apex (asterisk). (E) A 5-month follow-up radiograph of P3. (F) A 5-months follow-up CT view of P3 with completed apical formation, with periapical lesion (PL) around the root. 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{"pdf_hash": "4b866910f45093c6d94b4e34752fb10d1393091d", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. (A) Contrast-enhanced computed tomography demonstrated an upper abdominal cystic space-occupying lesion (arrow) in case 1. (B) Mass (indicated by the arrow) resected by laparoscopic-assisted resection by pulling out through the navel in case 1. The size of the mass was approximately 6.0x3.0x2.5 cm, and the wall was complete.", "width": 1194, "height": 452, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "ebbe704b-74c1-4e7d-ba75-dd655724ccd7", "label": "a", "points": [[81.4, 15.2], [81.4, 413.2], [607.6, 413.2], [607.6, 15.2]], "color": "yellow"}, {"id": "48d228b2-7983-486b-953d-196fbddec288", "label": "b", "points": [[654.8, 11.5], [654.8, 401.9], [1179.1, 401.9], [1179.1, 11.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Contrast", "start": 14, "end": 22, "id": 6}, {"text": "-", "start": 22, "end": 23, "id": 7}, {"text": "enhanced", "start": 23, "end": 31, "id": 8}, {"text": "computed", "start": 32, "end": 40, "id": 9}, {"text": "tomography", "start": 41, "end": 51, "id": 10}, {"text": "demonstrated", "start": 52, "end": 64, "id": 11}, {"text": "an", "start": 65, "end": 67, "id": 12}, {"text": "upper", "start": 68, "end": 73, "id": 13}, {"text": "abdominal", "start": 74, "end": 83, "id": 14}, {"text": "cystic", "start": 84, "end": 90, "id": 15}, {"text": "space", "start": 91, "end": 96, "id": 16}, {"text": "-", "start": 96, "end": 97, "id": 17}, {"text": "occupying", "start": 97, "end": 106, "id": 18}, {"text": "lesion", "start": 107, "end": 113, "id": 19}, {"text": "(", "start": 114, "end": 115, "id": 20}, {"text": "arrow", "start": 115, "end": 120, "id": 21}, {"text": ")", "start": 120, "end": 121, "id": 22}, {"text": "in", "start": 122, "end": 124, "id": 23}, {"text": "case", "start": 125, "end": 129, "id": 24}, {"text": "1", "start": 130, "end": 131, "id": 25}, {"text": ".", "start": 131, "end": 132, "id": 26}, {"text": "(", "start": 133, "end": 134, "id": 27}, {"text": "B", "start": 134, "end": 135, "id": 28}, {"text": ")", "start": 135, "end": 136, "id": 29}, {"text": "Mass", "start": 137, "end": 141, "id": 30}, {"text": "(", "start": 142, "end": 143, "id": 31}, {"text": "indicated", "start": 143, "end": 152, "id": 32}, {"text": "by", "start": 153, "end": 155, "id": 33}, {"text": "the", "start": 156, "end": 159, "id": 34}, {"text": "arrow", "start": 160, "end": 165, "id": 35}, {"text": ")", "start": 165, "end": 166, "id": 36}, {"text": "resected", "start": 167, "end": 175, "id": 37}, {"text": "by", "start": 176, "end": 178, "id": 38}, {"text": "laparoscopic", "start": 179, "end": 191, "id": 39}, {"text": "-", "start": 191, "end": 192, "id": 40}, {"text": "assisted", "start": 192, "end": 200, "id": 41}, {"text": "resection", "start": 201, "end": 210, "id": 42}, {"text": "by", "start": 211, "end": 213, "id": 43}, {"text": "pulling", "start": 214, "end": 221, "id": 44}, {"text": "out", "start": 222, "end": 225, "id": 45}, {"text": "through", "start": 226, "end": 233, "id": 46}, {"text": "the", "start": 234, "end": 237, "id": 47}, {"text": "navel", "start": 238, "end": 243, "id": 48}, {"text": "in", "start": 244, "end": 246, "id": 49}, {"text": "case", "start": 247, "end": 251, "id": 50}, {"text": "1", "start": 252, "end": 253, "id": 51}, {"text": ".", "start": 253, "end": 254, "id": 52}, {"text": "The", "start": 255, "end": 258, "id": 53}, {"text": "size", "start": 259, "end": 263, "id": 54}, {"text": "of", "start": 264, "end": 266, "id": 55}, {"text": "the", "start": 267, "end": 270, "id": 56}, {"text": "mass", "start": 271, "end": 275, "id": 57}, {"text": "was", "start": 276, "end": 279, "id": 58}, {"text": "approximately", "start": 280, "end": 293, "id": 59}, {"text": "6.0x3.0x2.5", "start": 294, "end": 305, "id": 60}, {"text": "cm", "start": 306, "end": 308, "id": 61}, {"text": ",", "start": 308, "end": 309, "id": 62}, {"text": "and", "start": 310, "end": 313, "id": 63}, {"text": "the", "start": 314, "end": 317, "id": 64}, {"text": "wall", "start": 318, "end": 322, "id": 65}, {"text": "was", "start": 323, "end": 326, "id": 66}, {"text": "complete", "start": 327, "end": 335, "id": 67}, {"text": ".", "start": 335, "end": 336, "id": 68}]}
{"pdf_hash": "6d36f43ed282e43e2db97fe52a1d19e3bec6f391", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 AA visualized in longitudinal and transverse plans from the diaphragm to the bifurcation of the aorta. Antero-posterior and latero-lateral outer diameters were measured in the transverse plane, at the largest portion of infrarenal aorta. 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{"pdf_hash": "ae5c70abbd8cc329f723a60ed6a53daf9c5ec9ab", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Imaging of this soft- tissue mass confirmed bony origin (mandibular mass) (A, arrow) Cytology showed round cell tumor and osteoblasts (B) immunohistochemistry proved neuroblastoma of mandible (Wright, 200\u00d7).", "width": 842, "height": 308, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "afc346e3-7ff7-43c7-8c95-aadf8e2237d4", "label": "a", "points": [[4.2, 0.4], [4.2, 301.1], [413.9, 301.1], [413.9, 0.4]], "color": "yellow"}, {"id": "efb5b12f-0734-49cf-b7ae-4e375f3de9f7", "label": "b", "points": [[431.2, 3.1], [431.2, 306.4], [840.9, 306.4], [840.9, 3.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Imaging", "start": 10, "end": 17, "id": 3}, {"text": "of", "start": 18, "end": 20, "id": 4}, {"text": "this", "start": 21, "end": 25, "id": 5}, {"text": "soft-", "start": 26, "end": 31, "id": 6}, {"text": "tissue", "start": 32, "end": 38, "id": 7}, {"text": "mass", "start": 39, "end": 43, "id": 8}, {"text": "confirmed", "start": 44, "end": 53, "id": 9}, {"text": "bony", "start": 54, "end": 58, "id": 10}, {"text": "origin", "start": 59, "end": 65, "id": 11}, {"text": "(", "start": 66, "end": 67, "id": 12}, {"text": "mandibular", "start": 67, "end": 77, "id": 13}, {"text": "mass", "start": 78, "end": 82, "id": 14}, {"text": ")", "start": 82, "end": 83, "id": 15}, {"text": "(", "start": 84, "end": 85, "id": 16}, {"text": "A", "start": 85, "end": 86, "id": 17}, {"text": ",", "start": 86, "end": 87, "id": 18}, {"text": "arrow", "start": 88, "end": 93, "id": 19}, {"text": ")", "start": 93, "end": 94, "id": 20}, {"text": "Cytology", "start": 95, "end": 103, "id": 21}, {"text": "showed", "start": 104, "end": 110, "id": 22}, {"text": "round", "start": 111, "end": 116, "id": 23}, {"text": "cell", "start": 117, "end": 121, "id": 24}, {"text": "tumor", "start": 122, "end": 127, "id": 25}, {"text": "and", "start": 128, "end": 131, "id": 26}, {"text": "osteoblasts", "start": 132, "end": 143, "id": 27}, {"text": "(", "start": 144, "end": 145, "id": 28}, {"text": "B", "start": 145, "end": 146, "id": 29}, {"text": ")", "start": 146, "end": 147, "id": 30}, {"text": "immunohistochemistry", "start": 148, "end": 168, "id": 31}, {"text": "proved", "start": 169, "end": 175, "id": 32}, {"text": "neuroblastoma", "start": 176, "end": 189, "id": 33}, {"text": "of", "start": 190, "end": 192, "id": 34}, {"text": "mandible", "start": 193, "end": 201, "id": 35}, {"text": "(", "start": 202, "end": 203, "id": 36}, {"text": "Wright", "start": 203, "end": 209, "id": 37}, {"text": ",", "start": 209, "end": 210, "id": 38}, {"text": "200\u00d7", "start": 211, "end": 215, "id": 39}, {"text": ")", "start": 215, "end": 216, "id": 40}, {"text": ".", "start": 216, "end": 217, "id": 41}]}
{"pdf_hash": "6cc2bf28484cf3fef81fd8267d7d7ee15ecf49c7", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig 2. Axial brain MRI, T1: diffuse white matter T1 hypointensity in a symmetric, confluent distribution, extending from (A) the centrum semiovale and corona radiata (B) corpus collosum (C) pons and (D) the atrophic medulla demonstrating bilateral Wallerian degeneration.", "width": 770, "height": 836, "subcaptions": {"b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "c": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 37, 38, 39, 40], "d": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52]}, "subfigures": [{"id": "73911777-b05e-4603-956f-e1f7490aada1", "label": "a", "points": [[3.7, 1], [3.7, 407.3], [360.1, 407.3], [360.1, 1]], "color": "yellow"}, {"id": "555d247f-c8d1-4031-aa34-f0ded382e41f", "label": "b", "points": [[408.7, 2.2], [408.7, 403.6], [765.1, 403.6], [765.1, 2.2]], "color": "cyan"}, {"id": "29eb3cf0-ee3b-4dc7-b90b-92dbaed486db", "label": "c", "points": [[2.5, 429.2], [2.5, 835.4], [363.7, 835.4], [363.7, 429.2]], "color": "magenta"}, {"id": "8c9e3305-926d-4c3b-af77-9aded2951cc0", "label": "d", "points": [[407.5, 428], [407.5, 833], [766.3, 833], [766.3, 428]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Axial", "start": 7, "end": 12, "id": 3}, {"text": "brain", "start": 13, "end": 18, "id": 4}, {"text": "MRI", "start": 19, "end": 22, "id": 5}, {"text": ",", "start": 22, "end": 23, "id": 6}, {"text": "T1", "start": 24, "end": 26, "id": 7}, {"text": ":", "start": 26, "end": 27, "id": 8}, {"text": "diffuse", "start": 28, "end": 35, "id": 9}, {"text": "white", "start": 36, "end": 41, "id": 10}, {"text": "matter", "start": 42, "end": 48, "id": 11}, {"text": "T1", "start": 49, "end": 51, "id": 12}, {"text": "hypointensity", "start": 52, "end": 65, "id": 13}, {"text": "in", "start": 66, "end": 68, "id": 14}, {"text": "a", "start": 69, "end": 70, "id": 15}, {"text": "symmetric", "start": 71, "end": 80, "id": 16}, {"text": ",", "start": 80, "end": 81, "id": 17}, {"text": "confluent", "start": 82, "end": 91, "id": 18}, {"text": "distribution", "start": 92, "end": 104, "id": 19}, {"text": ",", "start": 104, "end": 105, "id": 20}, {"text": "extending", "start": 106, "end": 115, "id": 21}, {"text": "from", "start": 116, "end": 120, "id": 22}, {"text": "(", "start": 121, "end": 122, "id": 23}, {"text": "A", "start": 122, "end": 123, "id": 24}, {"text": ")", "start": 123, "end": 124, "id": 25}, {"text": "the", "start": 125, "end": 128, "id": 26}, {"text": "centrum", "start": 129, "end": 136, "id": 27}, {"text": "semiovale", "start": 137, "end": 146, "id": 28}, {"text": "and", "start": 147, "end": 150, "id": 29}, {"text": "corona", "start": 151, "end": 157, "id": 30}, {"text": "radiata", "start": 158, "end": 165, "id": 31}, {"text": "(", "start": 166, "end": 167, "id": 32}, {"text": "B", "start": 167, "end": 168, "id": 33}, {"text": ")", "start": 168, "end": 169, "id": 34}, {"text": "corpus", "start": 170, "end": 176, "id": 35}, {"text": "collosum", "start": 177, "end": 185, "id": 36}, {"text": "(", "start": 186, "end": 187, "id": 37}, {"text": "C", "start": 187, "end": 188, "id": 38}, {"text": ")", "start": 188, "end": 189, "id": 39}, {"text": "pons", "start": 190, "end": 194, "id": 40}, {"text": "and", "start": 195, "end": 198, "id": 41}, {"text": "(", "start": 199, "end": 200, "id": 42}, {"text": "D", "start": 200, "end": 201, "id": 43}, {"text": ")", "start": 201, "end": 202, "id": 44}, {"text": "the", "start": 203, "end": 206, "id": 45}, {"text": "atrophic", "start": 207, "end": 215, "id": 46}, {"text": "medulla", "start": 216, "end": 223, "id": 47}, {"text": "demonstrating", "start": 224, "end": 237, "id": 48}, {"text": "bilateral", "start": 238, "end": 247, "id": 49}, {"text": "Wallerian", "start": 248, "end": 257, "id": 50}, {"text": "degeneration", "start": 258, "end": 270, "id": 51}, {"text": ".", "start": 270, "end": 271, "id": 52}]}
{"pdf_hash": "da0da1aa1e24e6dde0d7f4704b7e33f349dc9136", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 a Preoperative sagittal X-ray (the spinous fracture of C5), b postoperative sagittal X-ray", "width": 1008, "height": 482, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22]}, "subfigures": [{"id": "1e2d92e0-e4ac-458e-988a-66c9bf93c87e", "label": "a", "points": [[5, 0.5], [5, 479.9], [489.2, 479.9], [489.2, 0.5]], "color": "yellow"}, {"id": "541b6ca8-d2b1-48ef-b33e-9e61e8c0f776", "label": "b", "points": [[509.9, 8.5], [509.9, 479.9], [1002, 479.9], [1002, 8.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Preoperative", "start": 9, "end": 21, "id": 4}, {"text": "sagittal", "start": 22, "end": 30, "id": 5}, {"text": "X", "start": 31, "end": 32, "id": 6}, {"text": "-", "start": 32, "end": 33, "id": 7}, {"text": "ray", "start": 33, "end": 36, "id": 8}, {"text": "(", "start": 37, "end": 38, "id": 9}, {"text": "the", "start": 38, "end": 41, "id": 10}, {"text": "spinous", "start": 42, "end": 49, "id": 11}, {"text": "fracture", "start": 50, "end": 58, "id": 12}, {"text": "of", "start": 59, "end": 61, "id": 13}, {"text": "C5", "start": 62, "end": 64, "id": 14}, {"text": ")", "start": 64, "end": 65, "id": 15}, {"text": ",", "start": 65, "end": 66, "id": 16}, {"text": "b", "start": 67, "end": 68, "id": 17}, {"text": "postoperative", "start": 69, "end": 82, "id": 18}, {"text": "sagittal", "start": 83, "end": 91, "id": 19}, {"text": "X", "start": 92, "end": 93, "id": 20}, {"text": "-", "start": 93, "end": 94, "id": 21}, {"text": "ray", "start": 94, "end": 97, "id": 22}]}
{"pdf_hash": "28b092a5d70f3d274e7823d15af59d4b5231d8d5", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. LR-4 nodule and TACE outcome. An \u201cindex nodule\u201d between segment 5 and 8 was noted in a cirrhosis patient, which showed T1 hypointense (A). Arterial phase of enhancement showed centric foci of enhancement (B). The nodule washed out on portal venous phase (C). This nodule was grouped into LR-4. DSA showed abnormality of hepatic arteries (E), which favors a diagnosis of HCC. 11 months later, CT showed a \u201cdot\u201d high intensity which was lipiodol in the lesion (F).", "width": 716, "height": 678, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "c": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59], "d": [60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83], "e": [84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105]}, "subfigures": [{"id": "ee2f6098-67c9-448a-bdcb-2b0e6f85584c", "label": "a", "points": [[2.9, 0.9], [2.9, 217], [353.5, 217], [353.5, 0.9]], "color": "yellow"}, {"id": "87a01900-8a6b-4223-8407-02c79d3a5b9c", "label": "c", "points": [[4, 233.4], [4, 447.1], [352.4, 447.1], [352.4, 233.4]], "color": "magenta"}, {"id": 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{"pdf_hash": "aa4a28cc22f3f07ec09ede165c56fb1f44adc227", "fig_key": "Figure3", "fig_uri": "8-Figure3-1.png", "text": "Fig. 3. Histological sections of the body muscle and liver of blue gourami. (a, b, d, e) Phase-contrast micrographs ; (c, f) fluorescence micrographs. (a) Longitudinal section of body muscle from uninfected fish. (b) Longitudinal section of body muscle from PPD130/91(pGFPuv)-infected fish. (c) High magnification of muscle tissue shows numerous fluorescent bacteria. (d) Transverse section of liver from uninfected fish. (e) Transverse section of liver from PPD130/91(pGFPuv)-infected fish. (f) High magnification of liver section showing numerous fluorescent bacteria. 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{"pdf_hash": "59ae085326f39799de1b558bffd05597d22f41e9", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Immunocytochemical demonstration of the nuclear localization of hTERT staining in APA (A and B) and AC (C and D), that were hTERT mRNA and hTERT activity positive.", "width": 1096, "height": 818, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25]}, "subfigures": [{"id": "99465418-4e0b-4960-b868-7d252886fe5e", "label": "a", "points": [[32.9, 5.2], [32.9, 374], [543.7, 374], [543.7, 5.2]], "color": "yellow"}, {"id": "d794f3c2-7b32-476b-942c-e739c74d9158", "label": "a", "points": [[552.3, 374], [552.3, 3.5], [1052.7, 3.5], [1052.7, 374]], "color": "cyan"}, {"id": "47030d36-807b-4c2f-ace0-d300628e8691", "label": "b", "points": [[32.9, 391.3], [32.9, 772.2], [541.9, 772.2], [541.9, 391.3]], "color": "magenta"}, {"id": "440d0cd1-dc56-4806-bf8f-483a4daddc16", "label": "b", "points": [[559.3, 772.2], [559.3, 387.8], [1051, 387.8], [1051, 772.2]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Immunocytochemical", "start": 10, "end": 28, "id": 3}, {"text": "demonstration", "start": 29, "end": 42, "id": 4}, {"text": "of", "start": 43, "end": 45, "id": 5}, {"text": "the", "start": 46, "end": 49, "id": 6}, {"text": "nuclear", "start": 50, "end": 57, "id": 7}, {"text": "localization", "start": 58, "end": 70, "id": 8}, {"text": "of", "start": 71, "end": 73, "id": 9}, {"text": "hTERT", "start": 74, "end": 79, "id": 10}, {"text": "staining", "start": 80, "end": 88, "id": 11}, {"text": "in", "start": 89, "end": 91, "id": 12}, {"text": "APA", "start": 92, "end": 95, "id": 13}, {"text": "(", "start": 96, "end": 97, "id": 14}, {"text": "A", "start": 97, "end": 98, "id": 15}, {"text": "and", "start": 99, "end": 102, "id": 16}, {"text": "B", "start": 103, "end": 104, "id": 17}, {"text": ")", "start": 104, "end": 105, "id": 18}, {"text": "and", "start": 106, "end": 109, "id": 19}, {"text": "AC", "start": 110, "end": 112, "id": 20}, {"text": "(", "start": 113, "end": 114, "id": 21}, {"text": "C", "start": 114, "end": 115, "id": 22}, {"text": "and", "start": 116, "end": 119, "id": 23}, {"text": "D", "start": 120, "end": 121, "id": 24}, {"text": ")", "start": 121, "end": 122, "id": 25}, {"text": ",", "start": 122, "end": 123, "id": 26}, {"text": "that", "start": 124, "end": 128, "id": 27}, {"text": "were", "start": 129, "end": 133, "id": 28}, {"text": "hTERT", "start": 134, "end": 139, "id": 29}, {"text": "mRNA", "start": 140, "end": 144, "id": 30}, {"text": "and", "start": 145, "end": 148, "id": 31}, {"text": "hTERT", "start": 149, "end": 154, "id": 32}, {"text": "activity", "start": 155, "end": 163, "id": 33}, {"text": "positive", "start": 164, "end": 172, "id": 34}, {"text": ".", "start": 172, "end": 173, "id": 35}]}
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{"pdf_hash": "9be68ac59cd8920bd787c40b39cbaac4317fac1f", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Low-tube-voltage CT imaging of the liver. a Arterial-phase CT scan using 80-kVp shows strong arterial enhancement of HCC (arrow) as well as strong enhancement of the aorta. b Delayed-phase CT scan using 120-kVp shows washout of the lesion (arrow).", "width": 638, "height": 236, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57]}, "subfigures": [{"id": "099ca724-ca87-42bc-9556-d2679047306e", "label": "a", "points": [[0.2, 0.3], [0.2, 230.1], [313.6, 230.1], [313.6, 0.3]], "color": "yellow"}, {"id": "94eba7e9-2f1c-4140-8d99-57b55c7082b6", "label": "b", "points": [[326.7, 2.4], [326.7, 235.2], [636.2, 235.2], [636.2, 2.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Low", "start": 8, "end": 11, "id": 4}, {"text": "-", "start": 11, "end": 12, "id": 5}, {"text": "tube", "start": 12, "end": 16, "id": 6}, {"text": "-", "start": 16, "end": 17, "id": 7}, {"text": "voltage", "start": 17, "end": 24, "id": 8}, {"text": "CT", "start": 25, "end": 27, "id": 9}, {"text": "imaging", "start": 28, "end": 35, "id": 10}, {"text": "of", "start": 36, "end": 38, "id": 11}, {"text": "the", "start": 39, "end": 42, "id": 12}, {"text": "liver", "start": 43, "end": 48, "id": 13}, {"text": ".", "start": 48, "end": 49, "id": 14}, {"text": "a", "start": 50, "end": 51, "id": 15}, {"text": "Arterial", "start": 52, "end": 60, "id": 16}, {"text": "-", "start": 60, "end": 61, "id": 17}, {"text": "phase", "start": 61, "end": 66, "id": 18}, {"text": "CT", "start": 67, "end": 69, "id": 19}, {"text": "scan", "start": 70, "end": 74, "id": 20}, {"text": "using", "start": 75, "end": 80, "id": 21}, {"text": "80-kVp", "start": 81, "end": 87, "id": 22}, {"text": "shows", "start": 88, "end": 93, "id": 23}, {"text": "strong", "start": 94, "end": 100, "id": 24}, {"text": "arterial", "start": 101, "end": 109, "id": 25}, {"text": "enhancement", "start": 110, "end": 121, "id": 26}, {"text": "of", "start": 122, "end": 124, "id": 27}, {"text": "HCC", "start": 125, "end": 128, "id": 28}, {"text": "(", "start": 129, "end": 130, "id": 29}, {"text": "arrow", "start": 130, "end": 135, "id": 30}, {"text": ")", "start": 135, "end": 136, "id": 31}, {"text": "as", "start": 137, "end": 139, "id": 32}, {"text": "well", "start": 140, "end": 144, "id": 33}, {"text": "as", "start": 145, "end": 147, "id": 34}, {"text": "strong", "start": 148, "end": 154, "id": 35}, {"text": "enhancement", "start": 155, "end": 166, "id": 36}, {"text": "of", "start": 167, "end": 169, "id": 37}, {"text": "the", "start": 170, "end": 173, "id": 38}, {"text": "aorta", "start": 174, "end": 179, "id": 39}, {"text": ".", "start": 179, "end": 180, "id": 40}, {"text": "b", "start": 181, "end": 182, "id": 41}, {"text": "Delayed", "start": 183, "end": 190, "id": 42}, {"text": "-", "start": 190, "end": 191, "id": 43}, {"text": "phase", "start": 191, "end": 196, "id": 44}, {"text": "CT", "start": 197, "end": 199, "id": 45}, {"text": "scan", "start": 200, "end": 204, "id": 46}, {"text": "using", "start": 205, "end": 210, "id": 47}, {"text": "120-kVp", "start": 211, "end": 218, "id": 48}, {"text": "shows", "start": 219, "end": 224, "id": 49}, {"text": "washout", "start": 225, "end": 232, "id": 50}, {"text": "of", "start": 233, "end": 235, "id": 51}, {"text": "the", "start": 236, "end": 239, "id": 52}, {"text": "lesion", "start": 240, "end": 246, "id": 53}, {"text": "(", "start": 247, "end": 248, "id": 54}, {"text": "arrow", "start": 248, "end": 253, "id": 55}, {"text": ")", "start": 253, "end": 254, "id": 56}, {"text": ".", "start": 254, "end": 255, "id": 57}]}
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{"pdf_hash": "65165fafd71b454a26b5cdb5f4363a68ed2bcc75", "fig_key": "Figure4", "fig_uri": "2-Figure4-1.png", "text": "Figure 4. Case 2: Chest CT (A) prior to and (B) following three cycles of carboplatin and paclitaxel chemotherapy plus concurrent radiation therapy. Subsequent to chemotherapy, the tumor was markedly reduced in size on chest CT, and a partial remission was achieved. CT, computed tomography.", "width": 816, "height": 342, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [3, 4, 5, 6, 7, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "bdaa66dc-5a34-40b2-bb25-61da0753f0a8", "label": "a", "points": [[25.2, 3.7], [25.2, 302.7], [396.4, 302.7], [396.4, 3.7]], "color": "yellow"}, {"id": "5a324589-252c-4b03-8859-6a707b6e85ba", "label": "b", "points": [[433.8, 2.4], [433.8, 306.6], [812.8, 306.6], [812.8, 2.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Case", "start": 10, "end": 14, "id": 3}, {"text": "2", "start": 15, "end": 16, "id": 4}, {"text": ":", "start": 16, "end": 17, "id": 5}, {"text": "Chest", "start": 18, "end": 23, "id": 6}, {"text": "CT", "start": 24, "end": 26, "id": 7}, {"text": "(", "start": 27, "end": 28, "id": 8}, {"text": "A", "start": 28, "end": 29, "id": 9}, {"text": ")", "start": 29, "end": 30, "id": 10}, {"text": "prior", "start": 31, "end": 36, "id": 11}, {"text": "to", "start": 37, "end": 39, "id": 12}, {"text": "and", "start": 40, "end": 43, "id": 13}, {"text": "(", "start": 44, "end": 45, "id": 14}, {"text": "B", "start": 45, "end": 46, "id": 15}, {"text": ")", "start": 46, "end": 47, "id": 16}, {"text": "following", "start": 48, "end": 57, "id": 17}, {"text": "three", "start": 58, "end": 63, "id": 18}, {"text": "cycles", "start": 64, "end": 70, "id": 19}, {"text": "of", "start": 71, "end": 73, "id": 20}, {"text": "carboplatin", "start": 74, "end": 85, "id": 21}, {"text": "and", "start": 86, "end": 89, "id": 22}, {"text": "paclitaxel", "start": 90, "end": 100, "id": 23}, {"text": "chemotherapy", "start": 101, "end": 113, "id": 24}, {"text": "plus", "start": 114, "end": 118, "id": 25}, {"text": "concurrent", "start": 119, "end": 129, "id": 26}, {"text": "radiation", "start": 130, "end": 139, "id": 27}, {"text": "therapy", "start": 140, "end": 147, "id": 28}, {"text": ".", "start": 147, "end": 148, "id": 29}, {"text": "Subsequent", "start": 149, "end": 159, "id": 30}, {"text": "to", "start": 160, "end": 162, "id": 31}, {"text": "chemotherapy", "start": 163, "end": 175, "id": 32}, {"text": ",", "start": 175, "end": 176, "id": 33}, {"text": "the", "start": 177, "end": 180, "id": 34}, {"text": "tumor", "start": 181, "end": 186, "id": 35}, {"text": "was", "start": 187, "end": 190, "id": 36}, {"text": "markedly", "start": 191, "end": 199, "id": 37}, {"text": "reduced", "start": 200, "end": 207, "id": 38}, {"text": "in", "start": 208, "end": 210, "id": 39}, {"text": "size", "start": 211, "end": 215, "id": 40}, {"text": "on", "start": 216, "end": 218, "id": 41}, {"text": "chest", "start": 219, "end": 224, "id": 42}, {"text": "CT", "start": 225, "end": 227, "id": 43}, {"text": ",", "start": 227, "end": 228, "id": 44}, {"text": "and", "start": 229, "end": 232, "id": 45}, {"text": "a", "start": 233, "end": 234, "id": 46}, {"text": "partial", "start": 235, "end": 242, "id": 47}, {"text": "remission", "start": 243, "end": 252, "id": 48}, {"text": "was", "start": 253, "end": 256, "id": 49}, {"text": "achieved", "start": 257, "end": 265, "id": 50}, {"text": ".", "start": 265, "end": 266, "id": 51}, {"text": "CT", "start": 267, "end": 269, "id": 52}, {"text": ",", "start": 269, "end": 270, "id": 53}, {"text": "computed", "start": 271, "end": 279, "id": 54}, {"text": "tomography", "start": 280, "end": 290, "id": 55}, {"text": ".", "start": 290, "end": 291, "id": 56}]}
{"pdf_hash": "bba1211e5468d80753702ad09887841cdadb6a86", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Extensive severe tophaceous gout. (A) Extensive tophi in both hands. (B) Extensive gluteal tophi. (C) CT scan imaging of hypervascularized gouty tophi in buttocks. The nature of the lesions was confirmed by fine needle aspiration biopsy.", "width": 918, "height": 760, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23, 24], "c": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "2cdcbd05-b352-4af9-a6a0-ae67283581c3", "label": "a", "points": [[42.8, 31.7], [42.8, 369.5], [459, 369.5], [459, 31.7]], "color": "yellow"}, {"id": "a4f509cf-0790-4a7b-8255-5aa528909774", "label": "b", "points": [[502.5, 34.6], [502.5, 363.7], [914.4, 363.7], [914.4, 34.6]], "color": "cyan"}, {"id": "4263040a-d7cb-4f88-a547-42be829221d9", "label": "c", "points": [[45.7, 395.7], [45.7, 756.7], [469.2, 756.7], [469.2, 395.7]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Extensive", "start": 8, "end": 17, "id": 4}, {"text": "severe", "start": 18, "end": 24, "id": 5}, {"text": "tophaceous", "start": 25, "end": 35, "id": 6}, {"text": "gout", "start": 36, "end": 40, "id": 7}, {"text": ".", "start": 40, "end": 41, "id": 8}, {"text": "(", "start": 42, "end": 43, "id": 9}, {"text": "A", "start": 43, "end": 44, "id": 10}, {"text": ")", "start": 44, "end": 45, "id": 11}, {"text": "Extensive", "start": 46, "end": 55, "id": 12}, {"text": "tophi", "start": 56, "end": 61, "id": 13}, {"text": "in", "start": 62, "end": 64, "id": 14}, {"text": "both", "start": 65, "end": 69, "id": 15}, {"text": "hands", "start": 70, "end": 75, "id": 16}, {"text": ".", "start": 75, "end": 76, "id": 17}, {"text": "(", "start": 77, "end": 78, "id": 18}, {"text": "B", "start": 78, "end": 79, "id": 19}, {"text": ")", "start": 79, "end": 80, "id": 20}, {"text": "Extensive", "start": 81, "end": 90, "id": 21}, {"text": "gluteal", "start": 91, "end": 98, "id": 22}, {"text": "tophi", "start": 99, "end": 104, "id": 23}, {"text": ".", "start": 104, "end": 105, "id": 24}, {"text": "(", "start": 106, "end": 107, "id": 25}, {"text": "C", "start": 107, "end": 108, "id": 26}, {"text": ")", "start": 108, "end": 109, "id": 27}, {"text": "CT", "start": 110, "end": 112, "id": 28}, {"text": "scan", "start": 113, "end": 117, "id": 29}, {"text": "imaging", "start": 118, "end": 125, "id": 30}, {"text": "of", "start": 126, "end": 128, "id": 31}, {"text": "hypervascularized", "start": 129, "end": 146, "id": 32}, {"text": "gouty", "start": 147, "end": 152, "id": 33}, {"text": "tophi", "start": 153, "end": 158, "id": 34}, {"text": "in", "start": 159, "end": 161, "id": 35}, {"text": "buttocks", "start": 162, "end": 170, "id": 36}, {"text": ".", "start": 170, "end": 171, "id": 37}, {"text": "The", "start": 172, "end": 175, "id": 38}, {"text": "nature", "start": 176, "end": 182, "id": 39}, {"text": "of", "start": 183, "end": 185, "id": 40}, {"text": "the", "start": 186, "end": 189, "id": 41}, {"text": "lesions", "start": 190, "end": 197, "id": 42}, {"text": "was", "start": 198, "end": 201, "id": 43}, {"text": "confirmed", "start": 202, "end": 211, "id": 44}, {"text": "by", "start": 212, "end": 214, "id": 45}, {"text": "fine", "start": 215, "end": 219, "id": 46}, {"text": "needle", "start": 220, "end": 226, "id": 47}, {"text": "aspiration", "start": 227, "end": 237, "id": 48}, {"text": "biopsy", "start": 238, "end": 244, "id": 49}, {"text": ".", "start": 244, "end": 245, "id": 50}]}
{"pdf_hash": "6dcaa3b420d20117165cac4780483e25b106dbb1", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2: Axial CT scan of unenhanced (a) and portal venous phase (b) of a 63-year-old female (LBW: 49.1 kg; CM volume: 98 mL) allocated in Group A and unenhanced (c) and portal venous phase (d) of a 73-year-old female (LBW: 47.7 kg; CM volume: 95 mL) allocated in Group B. The patient in Group A achieved a higher CEI (62.0 HU) compared to the patient in Group B (40.8 HU). 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{"pdf_hash": "50d5895dfa22ba9d72bf8ce41a08e8bbb48f2028", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A, Histopathology of tissue specimen from February 26, 2009 cerebral lesion de-bulking shows chronic angiocentric lymphoid infiltrate with florid reactive changes and demyelination. B, April 2, 2009 MRI demonstrating increasing right temporal lobe lesion with irregular enhancement. C, Immunofluorescent studies of tissue slides with anti-Acanthamoeba serum ( + 1000). 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{"pdf_hash": "0cbfb65be4f2f7a5d78fd001db9aa4b366161d4b", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 This cervical spine demonstrated opposite characteristics in each transverse foramen. On the left side, FA, PTA and LMA are larger than those of the right side. Therefore, insertion of pedicle screws would be difficult, and lateral mass screws should be selected. Furthermore, longer sizes can be selected. In contrast, when the values of the right side are smaller than those of the left side, insertion of pedicle screws is easier. a FA (Rt). b FA (Lt). c PTA (Rt). d PTA (Lt). e LMA (Rt). f LMA (Lt)", "width": 946, "height": 1136, "subcaptions": {"a": [85, 86, 87, 88, 89, 90], "b": [91, 92, 93, 94, 95, 96], "c": [97, 98, 99, 100, 101, 102], "d": [103, 104, 105, 106, 107, 108], "e": [109, 110, 111, 112, 113, 114], "f": [115, 116, 117, 118, 119]}, "subfigures": [{"id": "b7e09b81-b878-482a-b0e8-17f592b172af", "label": "a", "points": [[1.2, 28.1], [1.2, 373.4], [460, 373.4], [460, 28.1]], "color": "yellow"}, {"id": "27c47d92-ee5d-4556-982c-ffbc10d70ce6", "label": "f", "points": [[473.4, 802.2], [473.4, 1131], [941.2, 1131], [941.2, 802.2]], "color": "deepskyblue"}, {"id": "1b4a992f-b921-4590-b69b-87a8302cdb8c", "label": "b", "points": [[465.9, 28.9], [465.9, 372.6], [939.7, 372.6], [939.7, 28.9]], "color": "deepskyblue"}, {"id": "1ef045df-6088-4f95-8d85-2c25c565dad8", "label": "c", "points": 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{"pdf_hash": "e5f0e2927388f49a86af215da5646c18ef68aa2e", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. The gross tumor volume (GTV) is represented by a 40-mm diameter cylinder of unit density, located at 4 different positions, roughly simulating movement during the breathing cycle. (a-c) Coronal views show the GTV at its inferiormost, mid, and superiormost positions. The planning target volume created by merging the GTVs and applying margins is shown as a white line. 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{"pdf_hash": "5414749aaa6b9c47eaab3b8c96299b68bf171677", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 Surgical treatment at the proximal humerusTypical chondroid matrix (white arrows) is visible in ap x-ray (a) and coronal (c) and axial (d) T1 dotarem contrast-enhanced MRI. The decision to perform surgery was made due to local pain, lesion size and radiological signs of aggressiveness with endosteal scalloping (red arrows). 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{"pdf_hash": "00934b667395ca85acf388eb199f4a8c550fbc8c", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 a Muscle MRI with coronary STIR sequence of the thighs in a patient with ASS. Compared with surrounding tissue, the muscles are generally brighter in color, most evident in the medial compartment (arrow), indicating general edema. The patient was scored with 36/36 points in the muscle edema score. b The correspondent control to the patient in (a) with less color difference between muscles and surrounding tissue indicating no muscle edema (score 0). c Axial T1-weighted image in an ASS patient with almost total fatty replacement anteriorly (Gouttalier score 4, light arrow) and fatty streaks with more muscle than fat tissue (Gouttalier score 2, dark arrow) posteriorly. d The correspondent control to the patient in (c) evaluated as normal muscle tissue (Goutallier score 0\u20131)", "width": 854, "height": 636, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "b": [59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87], "c": [88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 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{"pdf_hash": "2f7eb2781a95881c5aee28b11fad07dbf0a2bae9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIG. 1. Results of the chest radiography and computed tomography performed at the time of admission. Cardiomegaly and pulmonary infiltration in both lungs are evident with predominance in the lower lobes.", "width": 1008, "height": 476, "subcaptions": {"a": [4, 5, 6, 7, 8, 12, 13, 14, 15, 16, 17, 18], "b": [4, 5, 6, 10, 11, 12, 13, 14, 15, 16, 17, 18]}, "subfigures": [{"id": "cbe27e87-3c88-4677-bb28-7aeaee7ad96e", "label": "a", "points": [[6.6, 10.1], [6.6, 471.9], [482.8, 471.9], [482.8, 10.1]], "color": "yellow"}, {"id": "a3a83f72-3042-4ac8-92cd-1137cfb03fd9", "label": "b", "points": [[490.7, 6.9], [490.7, 473.5], [970, 473.5], [970, 6.9]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Results", "start": 8, "end": 15, "id": 4}, {"text": "of", "start": 16, "end": 18, "id": 5}, {"text": "the", "start": 19, "end": 22, "id": 6}, {"text": "chest", "start": 23, "end": 28, "id": 7}, {"text": "radiography", "start": 29, "end": 40, "id": 8}, {"text": "and", "start": 41, "end": 44, "id": 9}, {"text": "computed", "start": 45, "end": 53, "id": 10}, {"text": "tomography", "start": 54, "end": 64, "id": 11}, {"text": "performed", "start": 65, "end": 74, "id": 12}, {"text": "at", "start": 75, "end": 77, "id": 13}, {"text": "the", "start": 78, "end": 81, "id": 14}, {"text": "time", "start": 82, "end": 86, "id": 15}, {"text": "of", "start": 87, "end": 89, "id": 16}, {"text": "admission", "start": 90, "end": 99, "id": 17}, {"text": ".", "start": 99, "end": 100, "id": 18}, {"text": "Cardiomegaly", "start": 101, "end": 113, "id": 19}, {"text": "and", "start": 114, "end": 117, "id": 20}, {"text": "pulmonary", "start": 118, "end": 127, "id": 21}, {"text": "infiltration", "start": 128, "end": 140, "id": 22}, {"text": "in", "start": 141, "end": 143, "id": 23}, {"text": "both", "start": 144, "end": 148, "id": 24}, {"text": "lungs", "start": 149, "end": 154, "id": 25}, {"text": "are", "start": 155, "end": 158, "id": 26}, {"text": "evident", "start": 159, "end": 166, "id": 27}, {"text": "with", "start": 167, "end": 171, "id": 28}, {"text": "predominance", "start": 172, "end": 184, "id": 29}, {"text": "in", "start": 185, "end": 187, "id": 30}, {"text": "the", "start": 188, "end": 191, "id": 31}, {"text": "lower", "start": 192, "end": 197, "id": 32}, {"text": "lobes", "start": 198, "end": 203, "id": 33}, {"text": ".", "start": 203, "end": 204, "id": 34}]}
{"pdf_hash": "b5d89996cc347d4cb3d1f059ba8e90b94333acc1", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. A fine-needle aspiration biopsy specimen suspicious for papillary thyroid cancer (original magnification \u03eb510) demonstrating marked cellularity (A), papillary formation (B), and nuclear inclusions and grooves (arrows) (C) from a patient with a final pathologic diagnosis of papillary carcinoma.", "width": 634, "height": 606, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 27, 28, 29, 30, 31, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "c": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "173920e3-6768-4727-9c7a-37b64be4c937", "label": "a", "points": [[2.5, 217.3], [2.5, 599], [628.5, 599], [628.5, 217.3]], "color": "yellow"}, {"id": "9042abbd-6052-4d82-9a57-fa6f3c4e6bcb", "label": "b", "points": [[368.1, 5], [368.1, 211.3], [627.5, 211.3], [627.5, 5]], "color": "cyan"}, {"id": "68b8eb7b-c593-40df-b075-7073219ec582", "label": "c", "points": [[2.5, 1], [2.5, 208.3], [218.8, 208.3], [218.8, 1]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "fine", "start": 12, "end": 16, "id": 4}, {"text": "-", "start": 16, "end": 17, "id": 5}, {"text": "needle", "start": 17, "end": 23, "id": 6}, {"text": "aspiration", "start": 24, "end": 34, "id": 7}, {"text": "biopsy", "start": 35, "end": 41, "id": 8}, {"text": "specimen", "start": 42, "end": 50, "id": 9}, {"text": "suspicious", "start": 51, "end": 61, "id": 10}, {"text": "for", "start": 62, "end": 65, "id": 11}, {"text": "papillary", "start": 66, "end": 75, "id": 12}, {"text": "thyroid", "start": 76, "end": 83, "id": 13}, {"text": "cancer", "start": 84, "end": 90, "id": 14}, {"text": "(", "start": 91, "end": 92, "id": 15}, {"text": "original", "start": 92, "end": 100, "id": 16}, {"text": "magnification", "start": 101, "end": 114, "id": 17}, {"text": "\u03eb510", "start": 115, "end": 119, "id": 18}, {"text": ")", "start": 119, "end": 120, "id": 19}, {"text": "demonstrating", "start": 121, "end": 134, "id": 20}, {"text": "marked", "start": 135, "end": 141, "id": 21}, {"text": "cellularity", "start": 142, "end": 153, "id": 22}, {"text": "(", "start": 154, "end": 155, "id": 23}, {"text": "A", "start": 155, "end": 156, "id": 24}, {"text": ")", "start": 156, "end": 157, "id": 25}, {"text": ",", "start": 157, "end": 158, "id": 26}, {"text": "papillary", "start": 159, "end": 168, "id": 27}, {"text": "formation", "start": 169, "end": 178, "id": 28}, {"text": "(", "start": 179, "end": 180, "id": 29}, {"text": "B", "start": 180, "end": 181, "id": 30}, {"text": ")", "start": 181, "end": 182, "id": 31}, {"text": ",", "start": 182, "end": 183, "id": 32}, {"text": "and", "start": 184, "end": 187, "id": 33}, {"text": "nuclear", "start": 188, "end": 195, "id": 34}, {"text": "inclusions", "start": 196, "end": 206, "id": 35}, {"text": "and", "start": 207, "end": 210, "id": 36}, {"text": "grooves", "start": 211, "end": 218, "id": 37}, {"text": "(", "start": 219, "end": 220, "id": 38}, {"text": "arrows", "start": 220, "end": 226, "id": 39}, {"text": ")", "start": 226, "end": 227, "id": 40}, {"text": "(", "start": 228, "end": 229, "id": 41}, {"text": "C", "start": 229, "end": 230, "id": 42}, {"text": ")", "start": 230, "end": 231, "id": 43}, {"text": "from", "start": 232, "end": 236, "id": 44}, {"text": "a", "start": 237, "end": 238, "id": 45}, {"text": "patient", "start": 239, "end": 246, "id": 46}, {"text": "with", "start": 247, "end": 251, "id": 47}, {"text": "a", "start": 252, "end": 253, "id": 48}, {"text": "final", "start": 254, "end": 259, "id": 49}, {"text": "pathologic", "start": 260, "end": 270, "id": 50}, {"text": "diagnosis", "start": 271, "end": 280, "id": 51}, {"text": "of", "start": 281, "end": 283, "id": 52}, {"text": "papillary", "start": 284, "end": 293, "id": 53}, {"text": "carcinoma", "start": 294, "end": 303, "id": 54}, {"text": ".", "start": 303, "end": 304, "id": 55}]}
{"pdf_hash": "1385e8fb41ffbf9126d48191b2198b006bc12b5f", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4 Computed tomography colonography of a T3 stenosing lesion of the descending colon. 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{"pdf_hash": "473a1cedce407a12c6e5338cc790a99657620fb4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Immunohistochemical detection of MYC in representative Primary DLBCLs. Photomicrographs of select tumors and reactive tissue stained for MYC (positive staining = brown nuclei). Positive control (Burkitt lymphoma with a confirmed MYC translocation) revealed uniform, intense staining in .90% of tumor cells (Burkitt). In contrast, reactive lymphoid tissue revealed variable staining in only 10% of normal lymphocyte nuclei (Tonsil). Representative images from DLBCL cases and associated percent MYC+ tumor nuclei: Case 1, 90% MYC+; Case 7, 70% MYC+; and Cases 35 and 38, 30% MYC+. 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{"pdf_hash": "21747305221f2185cb592671eeabc5c6cb38c704", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2: A 52-year-old male who presented with worsening bouts of cold intolerance, 18 kg weight gain over 2 years, fatigue, decreased libido, polyuria, and 6 months of worsening vision. Endocrinological workup revealed central hypothyroidism, hypogonadotropic hypotestosteronism. T1 MRI with gadolinium (a and b) demonstrated a heterogeneously enhancing cystic suprasellar retrochiasmatic mass. The patient underwent an endonasal endoscopic transsellar, transplanum resection of the tumor. The pathology was consistent with craniopharyngioma. The postoperative MRI with gadolinium 1 day after surgery (c) demonstrated near total removal of the tumor with a small amount of tumor purposefully left along the posterior edge of the optic chiasm given its dense adhesions to the optic apparatus (white arrow). 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{"pdf_hash": "9b503c628adcf2559ac85d17d4293a8a31cec689", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. From left to right, axial view, coronal view, midsagital view with 3D reconstruction of the insula, and inflated cortical surface of a single subject with regions of interest (ROIs) in the insula, including the anterior insula in green and the posterior insula in orange.", "width": 1168, "height": 266, "subcaptions": {"a": [9, 10, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [12, 13, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "c": [15, 16, 17, 18, 19, 20, 21, 22, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "d": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "8c7181a0-b976-4fa9-9d18-be306487407f", "label": "a", "points": [[1, 3.4], [1, 252.5], [231.6, 252.5], [231.6, 3.4]], "color": "yellow"}, {"id": "ac08f7fc-817e-4d5f-8d73-df7df3e76a53", "label": "b", "points": [[240.9, 5.2], [240.9, 252.5], [488.1, 252.5], [488.1, 5.2]], "color": "cyan"}, {"id": "6da03898-d415-469c-bd32-2a294ecf855f", "label": "c", "points": [[513.9, 1.5], [513.9, 248.8], [833.1, 248.8], [833.1, 1.5]], "color": "magenta"}, {"id": "78c260bd-932e-4206-a46d-ce2494c2335c", "label": "d", "points": [[840.5, 1.5], [840.5, 261.7], [1159.7, 261.7], [1159.7, 1.5]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "From", "start": 8, "end": 12, "id": 4}, {"text": "left", "start": 13, "end": 17, "id": 5}, {"text": "to", "start": 18, "end": 20, "id": 6}, {"text": "right", "start": 21, "end": 26, "id": 7}, {"text": ",", "start": 26, "end": 27, "id": 8}, {"text": "axial", "start": 28, "end": 33, "id": 9}, {"text": "view", "start": 34, "end": 38, "id": 10}, {"text": ",", "start": 38, "end": 39, "id": 11}, {"text": "coronal", "start": 40, "end": 47, "id": 12}, {"text": "view", "start": 48, "end": 52, "id": 13}, {"text": ",", "start": 52, "end": 53, "id": 14}, {"text": "midsagital", "start": 54, "end": 64, "id": 15}, {"text": "view", "start": 65, "end": 69, "id": 16}, {"text": "with", "start": 70, "end": 74, "id": 17}, {"text": "3D", "start": 75, "end": 77, "id": 18}, {"text": "reconstruction", "start": 78, "end": 92, "id": 19}, {"text": "of", "start": 93, "end": 95, "id": 20}, {"text": "the", "start": 96, "end": 99, "id": 21}, {"text": "insula", "start": 100, "end": 106, "id": 22}, {"text": ",", "start": 106, "end": 107, "id": 23}, {"text": "and", "start": 108, "end": 111, "id": 24}, {"text": "inflated", "start": 112, "end": 120, "id": 25}, {"text": "cortical", "start": 121, "end": 129, "id": 26}, {"text": "surface", "start": 130, "end": 137, "id": 27}, {"text": "of", "start": 138, "end": 140, "id": 28}, {"text": "a", "start": 141, "end": 142, "id": 29}, {"text": "single", "start": 143, "end": 149, "id": 30}, {"text": "subject", "start": 150, "end": 157, "id": 31}, {"text": "with", "start": 158, "end": 162, "id": 32}, {"text": "regions", "start": 163, "end": 170, "id": 33}, {"text": "of", "start": 171, "end": 173, "id": 34}, {"text": "interest", "start": 174, "end": 182, "id": 35}, {"text": "(", "start": 183, "end": 184, "id": 36}, {"text": "ROIs", "start": 184, "end": 188, "id": 37}, {"text": ")", "start": 188, "end": 189, "id": 38}, {"text": "in", "start": 190, "end": 192, "id": 39}, {"text": "the", "start": 193, "end": 196, "id": 40}, {"text": "insula", "start": 197, "end": 203, "id": 41}, {"text": ",", "start": 203, "end": 204, "id": 42}, {"text": "including", "start": 205, "end": 214, "id": 43}, {"text": "the", "start": 215, "end": 218, "id": 44}, {"text": "anterior", "start": 219, "end": 227, "id": 45}, {"text": "insula", "start": 228, "end": 234, "id": 46}, {"text": "in", "start": 235, "end": 237, "id": 47}, {"text": "green", "start": 238, "end": 243, "id": 48}, {"text": "and", "start": 244, "end": 247, "id": 49}, {"text": "the", "start": 248, "end": 251, "id": 50}, {"text": "posterior", "start": 252, "end": 261, "id": 51}, {"text": "insula", "start": 262, "end": 268, "id": 52}, {"text": "in", "start": 269, "end": 271, "id": 53}, {"text": "orange", "start": 272, "end": 278, "id": 54}, {"text": ".", "start": 278, "end": 279, "id": 55}]}
{"pdf_hash": "c09caf9ebbbb43eedfadbb4b77e0091b58a7b69d", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig. 3 CPE out performs manual segmentation in complex and critical cases. a As an example of SEEG complexity, we show MRI and thresholded post-implant CT scans for one subject from our cohort. Contacts are shown as groups of white voxels. This case illustrates the complexity of SEEG implants with electrode shafts following non-planar directions (e.g. X), shafts targeting almost the same geometrical point (e.g. R and R'). b CPE segments all contacts (green spheres) belonging to each electrode from post-implant CT scans, represented here as red 3D meshes obtained tesselleting the thresholded data to ease visualization. c Show the right pial surface with 3D post-implant thresholded-CT meshes and the cut plane used in panel d where the example of X and X' electrodes are shown. 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{"pdf_hash": "b0c1e454a1086b1a5841c3d78856638c84ad7551", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 A 46-year-old woman underwent cervical corpectomy and fusion with a titanium mesh cage for OPLL. 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{"pdf_hash": "ef47fa1872c1f2f9ffdd17e123fccd0c172a4a96", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Effect of homoeopathic remedies on oesophageal cancer regression. (A) Barium meal-X-ray exhibits a large proximal filling defect with the dilated portion of the oesophagus of a 75-year-old male patient representing a tumor. (B) A histopathology slide of oesophageal carcinoma samples collected by endoscopy from the same patient. (C) Barium meal-X-ray exhibits a complete regression of the disease. 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{"pdf_hash": "15ead31cdf99ce9d9155b047a4d5ec314ddb15a2", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Lung lobe torsion in case 2. B-mode ultrasound image (A) showing consolidated lung lobe. A fluid bronchogram (arrow) and dilated vascular structure (arrowhead) can be seen in the central portion of the consolidated lung lobe. Contrast harmonic mode ultrasound image of the same lesions before the injection of the contrast agent (B). 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{"pdf_hash": "09a7500e7defc201f88a685aced71e2ed036a41c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. T2-weighted MRI 3 days before the third craniotomy (at 30 weeks gestation of a twin pregnancy) showing a 7 \u00c2 6 \u00c2 5 cm (anterior-posterior \u00c2 transverse \u00c2 craniocaudal) mass within the left frontoparietal region on axial view (A), with the superior aspect of the mass involving the pre-and post-central gyri on sagittal view (B). 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{"pdf_hash": "4eb63a04acc262b91a8ae538a0010b229022510a", "fig_key": "Figure5", "fig_uri": "9-Figure5-1.png", "text": "Figure 5 Coronal view of the regional FA reductions between groups in anterior brain: the top row indicates regions of the tracts of interest (TOIs) analysis for comparison with the voxel-wise analyses in the rows below. The second row (FTD<CN) shows FA reductions in FTD relative to cognitively normal involving the anterior frontal and temporal brain. The third row (AD<CN) shows the regional FA reductions in Alzheimer's disease relative to cognitively normal involving only a few regions in left anterior cingulum and bilateral uncinate fibres. The fourth row (FTD<AD) shows FA reductions in FTD relative to Alzheimer's disease indicating FTD had significantly lower FA in vast regions of bilateral frontal lobes including anterior corpus callosum, bilateral anterior cingulum, uncinate fibres and anterior limb of internal capsule. Last row (T1WI) depicts the anatomical locations on a T 1 -weighted brain template. 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{"pdf_hash": "48a8b533ececb9d390f38477ecb5958dc0a9fa00", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. A 21-year-old woman with a molar pregnancy. (A) Sagittal and coronal transvaginal sonography images, and (B) sagittal, T2-weighted pelvic MR images showing a heterogeneous molar mass at the time of preliminary diagnosis. At follow-up, the disease progressed to choriocarcinoma. 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{"pdf_hash": "012d5395dae06787e0d991e293ec3df999dd5734", "fig_key": "Figure8", "fig_uri": "24-Figure8-1.png", "text": "Figure 8. Axial perfusion rate maps obtained by FAIR True-FISP with (a) and without (b) the dual navigator-gated technique in the same scale. The kidneys are clearly delineated in the dual navigator-gated FAIR True-FISP perfusion image (a). The perfusion values in (b) (without navigator gating) are overestimated because of respiratory motion. 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{"pdf_hash": "a9fc045880983f2d7552cdd7441309d616e8546f", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "FIG 3. (a) Diffusion-weighted imaging (b value=1000 s/mm2) shows hyperintense lesions at the pons (arrow) and bilateral cerebellum (arrowheads). (b) The apparent diffusion", "width": 610, "height": 1140, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "d3556269-6798-4835-96fd-778570987191", "label": "a", "points": [[20, 18.8], [20, 529.9], [590, 529.9], [590, 18.8]], "color": "yellow"}, {"id": "d6e3b328-72fd-4a44-bd9d-a08a2760c881", "label": "b", "points": [[21, 538.9], [21, 1117.9], [591, 1117.9], [591, 538.9]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": "3", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "(", "start": 7, "end": 8, "id": 3}, {"text": "a", "start": 8, "end": 9, "id": 4}, {"text": ")", "start": 9, "end": 10, "id": 5}, {"text": "Diffusion", "start": 11, "end": 20, "id": 6}, {"text": "-", "start": 20, "end": 21, "id": 7}, {"text": "weighted", "start": 21, "end": 29, "id": 8}, {"text": "imaging", "start": 30, "end": 37, "id": 9}, {"text": "(", "start": 38, "end": 39, "id": 10}, {"text": "b", "start": 39, "end": 40, "id": 11}, {"text": "value=1000", "start": 41, "end": 51, "id": 12}, {"text": "s", "start": 52, "end": 53, "id": 13}, {"text": "/", "start": 53, "end": 54, "id": 14}, {"text": "mm2", "start": 54, "end": 57, "id": 15}, {"text": ")", "start": 57, "end": 58, "id": 16}, {"text": "shows", "start": 59, "end": 64, "id": 17}, {"text": "hyperintense", "start": 65, "end": 77, "id": 18}, {"text": "lesions", "start": 78, "end": 85, "id": 19}, {"text": "at", "start": 86, "end": 88, "id": 20}, {"text": "the", "start": 89, "end": 92, "id": 21}, {"text": "pons", "start": 93, "end": 97, "id": 22}, {"text": "(", "start": 98, "end": 99, "id": 23}, {"text": "arrow", "start": 99, "end": 104, "id": 24}, {"text": ")", "start": 104, "end": 105, "id": 25}, {"text": "and", "start": 106, "end": 109, "id": 26}, {"text": "bilateral", "start": 110, "end": 119, "id": 27}, {"text": "cerebellum", "start": 120, "end": 130, "id": 28}, {"text": "(", "start": 131, "end": 132, "id": 29}, {"text": "arrowheads", "start": 132, "end": 142, "id": 30}, {"text": ")", "start": 142, "end": 143, "id": 31}, {"text": ".", "start": 143, "end": 144, "id": 32}, {"text": "(", "start": 145, "end": 146, "id": 33}, {"text": "b", "start": 146, "end": 147, "id": 34}, {"text": ")", "start": 147, "end": 148, "id": 35}, {"text": "The", "start": 149, "end": 152, "id": 36}, {"text": "apparent", "start": 153, "end": 161, "id": 37}, {"text": "diffusion", "start": 162, "end": 171, "id": 38}]}
{"pdf_hash": "f9a8b8a093618a15a89dafa69d0e4337d3aa03e6", "fig_key": "Figure10", "fig_uri": "12-Figure10-1.png", "text": "Fig. 10 A 46-year-old man with no significant medical history presents with abdominal pain and low-grade fever. (a) An axial CT abdomen postcontrast image demonstrates ill-defined fat stranding (arrow) surrounding the proximal abdominal aorta at the level of the celiac artery origin. (b) A follow-up axial post-contrast CT scan of the abdomen performed 3 days later for worsening abdominal pain shows an interval increase in the severity of periaortic fat stranding (arrows). 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{"pdf_hash": "d94f86a16c192866be9076c7cd1973a01d2e4d07", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Intersegmental plane depicted on iodized-oil CT in a 61-year-old female with hepatocellular carcinoma in the left lateral segment. A. Portal venous phase CT image shows the umbilical portion of the left portal vein. B. Small peripheral rim-enhancing tumor nodule with central low attenuation (arrows) is noted in the section below the umbilical portion. C. Proper hepatic arteriogram shows the small tumor staining below the S3 hepatic artery. However, selective S3 hepatic arteriogram (no figure shown) shows no tumor staining. D. Selective S2 hepatic arteriogram shows the tumor staining. Segmental chemoembolization of S2 was performed. E. 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{"pdf_hash": "e863cabf7948fd4dca98940f0e74898dabc80f0b", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 Organization of colony and zooids in Crisia eburnea. Photographs of live animals (a-b) and semithin sections (C-E). a A part of colony. b The same colony in higher magnification: tentacles and pores (arrowheads) in the wall of cystids are visible. c Sagittal longitudinal section of distal portion of zooid; tentacles semi-retracted. d Eight tentacles in the cross section. e Cross section of two branches of the digestive tract. Abbreviations: a \u2013 anus; as \u2013 atrial sphincter; ca \u2013 cardia; cae \u2013 caecum; cl \u2013 calcified layer; cg \u2013 cerebral ganglion; ec \u2013 epidermis; es \u2013 esophagus; int \u2013 intestine; lph \u2013 lophophore; mo \u2013 mouth; ms \u2013 membranous sac; pe \u2013 unmineralized cuticle; ph \u2013 pharynx; py - pylorus; t \u2013 tentacle; ts \u2013 tentacle sheath; z \u2013 zooid", "width": 852, "height": 1426, "subcaptions": {"a": [32, 33, 34, 35, 12, 13, 14, 15, 16, 17, 18, 19, 20, 29, 30, 31], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20, 29, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "c": [22, 23, 24, 25, 26, 27, 28, 29, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72], "d": [73, 74, 75, 76, 77, 78, 79, 80, 22, 23, 24, 25, 26, 27, 28, 29], "e": [89, 90, 88, 91, 81, 82, 83, 84, 85, 22, 23, 24, 25, 26, 27, 28, 29, 86, 87]}, "subfigures": [{"id": "817744d6-a788-45fc-802d-e9070d24a7a8", "label": "a", 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{"pdf_hash": "64051fe18ad1f603097b080579230eba03aea5f1", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. One-millimeter axial images from high-resolution computed tomography of the chest. A, Soft tissue window image shows bilateral dependent lung consolidation with focal areas of low attenuation (arrows). B, Lung window image shows areas adjacent to consolidation with smooth interlobular septal thickening and superimposed ground-glass opacity (crazy-paving pattern [arrow]).", "width": 1334, "height": 488, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "a919371c-89f0-423e-b62e-c94452e06a37", "label": "a", "points": [[1.1, 2.1], [1.1, 459.4], [656.5, 459.4], [656.5, 2.1]], "color": "yellow"}, {"id": "3c2b18ad-d5cb-4598-8209-0bdfa3b03088", "label": "b", "points": [[669.2, 0], [669.2, 463.7], [1322.5, 463.7], [1322.5, 0]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "One", "start": 10, "end": 13, "id": 3}, {"text": "-", "start": 13, "end": 14, "id": 4}, {"text": "millimeter", "start": 14, "end": 24, "id": 5}, {"text": "axial", "start": 25, "end": 30, "id": 6}, {"text": "images", "start": 31, "end": 37, "id": 7}, {"text": "from", "start": 38, "end": 42, "id": 8}, {"text": "high", "start": 43, "end": 47, "id": 9}, {"text": "-", "start": 47, "end": 48, "id": 10}, {"text": "resolution", "start": 48, "end": 58, "id": 11}, {"text": "computed", "start": 59, "end": 67, "id": 12}, {"text": "tomography", "start": 68, "end": 78, "id": 13}, {"text": "of", "start": 79, "end": 81, "id": 14}, {"text": "the", "start": 82, "end": 85, "id": 15}, {"text": "chest", "start": 86, "end": 91, "id": 16}, {"text": ".", "start": 91, "end": 92, "id": 17}, {"text": "A", "start": 93, "end": 94, "id": 18}, {"text": ",", "start": 94, "end": 95, "id": 19}, {"text": "Soft", "start": 96, "end": 100, "id": 20}, {"text": "tissue", "start": 101, "end": 107, "id": 21}, {"text": "window", "start": 108, "end": 114, "id": 22}, {"text": "image", "start": 115, "end": 120, "id": 23}, {"text": "shows", "start": 121, "end": 126, "id": 24}, {"text": "bilateral", "start": 127, "end": 136, "id": 25}, {"text": "dependent", "start": 137, "end": 146, "id": 26}, {"text": "lung", "start": 147, "end": 151, "id": 27}, {"text": "consolidation", "start": 152, "end": 165, "id": 28}, {"text": "with", "start": 166, "end": 170, "id": 29}, {"text": "focal", "start": 171, "end": 176, "id": 30}, {"text": "areas", "start": 177, "end": 182, "id": 31}, {"text": "of", "start": 183, "end": 185, "id": 32}, {"text": "low", "start": 186, "end": 189, "id": 33}, {"text": "attenuation", "start": 190, "end": 201, "id": 34}, {"text": "(", "start": 202, "end": 203, "id": 35}, {"text": "arrows", "start": 203, "end": 209, "id": 36}, {"text": ")", "start": 209, "end": 210, "id": 37}, {"text": ".", "start": 210, "end": 211, "id": 38}, {"text": "B", "start": 212, "end": 213, "id": 39}, {"text": ",", "start": 213, "end": 214, "id": 40}, {"text": "Lung", "start": 215, "end": 219, "id": 41}, {"text": "window", "start": 220, "end": 226, "id": 42}, {"text": "image", "start": 227, "end": 232, "id": 43}, {"text": "shows", "start": 233, "end": 238, "id": 44}, {"text": "areas", "start": 239, "end": 244, "id": 45}, {"text": "adjacent", "start": 245, "end": 253, "id": 46}, {"text": "to", "start": 254, "end": 256, "id": 47}, {"text": "consolidation", "start": 257, "end": 270, "id": 48}, {"text": "with", "start": 271, "end": 275, "id": 49}, {"text": "smooth", "start": 276, "end": 282, "id": 50}, {"text": "interlobular", "start": 283, "end": 295, "id": 51}, {"text": "septal", "start": 296, "end": 302, "id": 52}, {"text": "thickening", "start": 303, "end": 313, "id": 53}, {"text": "and", "start": 314, "end": 317, "id": 54}, {"text": "superimposed", "start": 318, "end": 330, "id": 55}, {"text": "ground", "start": 331, "end": 337, "id": 56}, {"text": "-", "start": 337, "end": 338, "id": 57}, {"text": "glass", "start": 338, "end": 343, "id": 58}, {"text": "opacity", "start": 344, "end": 351, "id": 59}, {"text": "(", "start": 352, "end": 353, "id": 60}, {"text": "crazy", "start": 353, "end": 358, "id": 61}, {"text": "-", "start": 358, "end": 359, "id": 62}, {"text": "paving", "start": 359, "end": 365, "id": 63}, {"text": "pattern", "start": 366, "end": 373, "id": 64}, {"text": "[", "start": 374, "end": 375, "id": 65}, {"text": "arrow", "start": 375, "end": 380, "id": 66}, {"text": "]", "start": 380, "end": 381, "id": 67}, {"text": ")", "start": 381, "end": 382, "id": 68}, {"text": ".", "start": 382, "end": 383, "id": 69}]}
{"pdf_hash": "4b0b6964107307ecdfb81a8eaec5d25c0bb77ddd", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 A 38-year-old patient with grade 3 invasive ductal carcinoma of the right breast pT2, pN2, M0. Illustration of the acquisition protocol of PET/MR and PET/CT examinations. Whole-body Dixon T1W MRI (a) with corresponding PET (b) and fusion PET/MR images (c) in the supine position, followed by dedicated breast MRI (d) with corresponding PET (e) acquisition and fused PET/MR (f) in the prone position and late PET/CT (g, h, i) supine acquisitions. Notice the mass lesion of the inner upper quadrant (arrows in all images). The lesion is detected on enhanced breast MRI (d) because of its contrast uptake. It is also clearly visible on PET in all three acquisitions (b, e, h) because of its intense metabolism. 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{"pdf_hash": "1603338258c3a6cacd70117ae3427882359e5dfb", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. Transverse images show HCC in a 51-year-old man. Images were arranged to depict the same lesion at the same level in the anterior segment of the right hepatic lobe. Transverse dual-phase spiral CT scans show that the lesion is inhomogeneously enhanced on the image obtained during the (a) arterial phase and predominantly hypoattenuating on the image obtained during the (b) portal venous phase. Despite these features, readers of the dual-phase spiral CT scans classified this as a benign lesion. (c) T1-weighted (170/4.4; flip angle, 80\u00b0) Mn-DPDP\u2013 enhanced MR image shows marked, slightly inhomogeneous enhancement. The conspicuity of the lesion (white arrow) greatly improved because of the presence of an unenhanced hypointense rim (tumor capsule) marking the border of the lesion. 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{"pdf_hash": "465e1b0fcb7b6cadb964011671c34e89eb4a24ee", "fig_key": "Figure8", "fig_uri": "7-Figure8-1.png", "text": "Fig. 8. Scanning electron micrographs illustrating the toughening mechanisms during crack growth in human coronal dentin. (a) crack extension in inner dentin. The crack primarily extends from lumen to lumen as shown with the white arrows. Some degree of peritubular microcraking is also observed at the crack tip as outlined (white encircled area). (b) Micrograph showing the presence of ligaments bridging the crack in inner dentin (arrows). Notice that the majority of bridging involves bundles of tubules as evident at this lower magnification. 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{"pdf_hash": "896e0f75d3396f155f7a7770159a60b9ff388308", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Left pelvic ureteral injury during hysterectomy managed by retrograde ureteral stenting. (A) A 55-year-old woman, 4 weeks postvaginal hysterectomy, with vaginal leakage of urine. Left retrograde ureterogram demonstrates extravasation from the left pelvic ureter. (B) Internalized double pigtail ureteral stent was successfully placed with cystoscopic guidance. (C) Six weeks later, retrograde ureterogram shows complete healing of the ureter. 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{"pdf_hash": "ca4f47435ca163a926c019addfc4c05535ec3a06", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 Transverse sections in rat retina at 7 days after KA injection using H-E staining. In control retina, five, well organized retinal layers are seen (A). In the KA-injected group, the thickness of retina is markedly reduced due to loss of internal nuclear (INL) and internal plexiform layers (IPL) (B). 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{"pdf_hash": "f49e693ddb4d5452314eecfa82161a5178e6a0aa", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Figure 6. Double immunofluorescence for tubulin (A and C) and for centrosome (B and D) on cells treated with CD alone (A and B) and with both CD and TX (C and D). Note that in both cases, Mts are present in the extensions and originate from the centrosome which has an axial position (arrows, A and C). The apparently larger cell on the right in C and D was near the edge of the coverslip and thus pulled apart in all directions by capillary forces: one can see that Mts run close to the cell surface. 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{"pdf_hash": "7ec30a0d3a03d38ed5b62ede05ece9919ed43f07", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Figure 1. A CT scan showing a combined left basal ganglia hematoma (Figure 1, A) when the patient developed motor weakness in his right extremities during initial admission. A CT scan on second admission revealed a larger left basal ganglia hematoma (Figure 1, B).", "width": 564, "height": 1056, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52]}, "subfigures": [{"id": "2a93db36-b4b4-41b9-8813-79808e6922a9", "label": "a", "points": [[43, 6.8], [43, 492.8], [528, 492.8], [528, 6.8]], "color": "yellow"}, {"id": "ad4d5cb8-3dd8-4c8e-a31b-23a35c687fee", "label": "b", "points": [[43, 527.8], [43, 1016.8], [531, 1016.8], [531, 527.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "CT", "start": 12, "end": 14, "id": 4}, {"text": "scan", "start": 15, "end": 19, "id": 5}, {"text": "showing", "start": 20, "end": 27, "id": 6}, {"text": "a", "start": 28, "end": 29, "id": 7}, {"text": "combined", "start": 30, "end": 38, "id": 8}, {"text": "left", "start": 39, "end": 43, "id": 9}, {"text": "basal", "start": 44, "end": 49, "id": 10}, {"text": "ganglia", "start": 50, "end": 57, "id": 11}, {"text": "hematoma", "start": 58, "end": 66, "id": 12}, {"text": "(", "start": 67, "end": 68, "id": 13}, {"text": "Figure", "start": 68, "end": 74, "id": 14}, {"text": "1", "start": 75, "end": 76, "id": 15}, {"text": ",", "start": 76, "end": 77, "id": 16}, {"text": "A", "start": 78, "end": 79, "id": 17}, {"text": ")", "start": 79, "end": 80, "id": 18}, {"text": "when", "start": 81, "end": 85, "id": 19}, {"text": "the", "start": 86, "end": 89, "id": 20}, {"text": "patient", "start": 90, "end": 97, "id": 21}, {"text": "developed", "start": 98, "end": 107, "id": 22}, {"text": "motor", "start": 108, "end": 113, "id": 23}, {"text": "weakness", "start": 114, "end": 122, "id": 24}, {"text": "in", "start": 123, "end": 125, "id": 25}, {"text": "his", "start": 126, "end": 129, "id": 26}, {"text": "right", "start": 130, "end": 135, "id": 27}, {"text": "extremities", "start": 136, "end": 147, "id": 28}, {"text": "during", "start": 148, "end": 154, "id": 29}, {"text": "initial", "start": 155, "end": 162, "id": 30}, {"text": "admission", "start": 163, "end": 172, "id": 31}, {"text": ".", "start": 172, "end": 173, "id": 32}, {"text": "A", "start": 174, "end": 175, "id": 33}, {"text": "CT", "start": 176, "end": 178, "id": 34}, {"text": "scan", "start": 179, "end": 183, "id": 35}, {"text": "on", "start": 184, "end": 186, "id": 36}, {"text": "second", "start": 187, "end": 193, "id": 37}, {"text": "admission", "start": 194, "end": 203, "id": 38}, {"text": "revealed", "start": 204, "end": 212, "id": 39}, {"text": "a", "start": 213, "end": 214, "id": 40}, {"text": "larger", "start": 215, "end": 221, "id": 41}, {"text": "left", "start": 222, "end": 226, "id": 42}, {"text": "basal", "start": 227, "end": 232, "id": 43}, {"text": "ganglia", "start": 233, "end": 240, "id": 44}, {"text": "hematoma", "start": 241, "end": 249, "id": 45}, {"text": "(", "start": 250, "end": 251, "id": 46}, {"text": "Figure", "start": 251, "end": 257, "id": 47}, {"text": "1", "start": 258, "end": 259, "id": 48}, {"text": ",", "start": 259, "end": 260, "id": 49}, {"text": "B", "start": 261, "end": 262, "id": 50}, {"text": ")", "start": 262, "end": 263, "id": 51}, {"text": ".", "start": 263, "end": 264, "id": 52}]}
{"pdf_hash": "32427ab9a7a7f23facae5fa57881568c52f7f415", "fig_key": "Figure6", "fig_uri": "11-Figure6-1.png", "text": "Figure 6 NF-kB and p38 MAP kinase activation in cultured astrocytes exposed to purified myelin. (A) Nuclear translocation (Hoechst dye 33342, cyan) of the NF-kB subunit p65 (a' and b', red) after 2 h of exposure with myelin debris (b and b') in GFAPlabelled astrocytes (a and b, grey). (B) astroglial p65 phosphorylation (flow cytometry); (C) time course (0-60 min) of IkBa degradation with maximum after 45 min of myelin exposure (flow cytometry). (C') Blockade of IkBa degradation after 45 min of myelin exposure by pretreatment with Dynasore (0.1 mM in 1:500 DMSO, 30 min). (D) Increased phosphorylation of p38 MAPK after stimulation with myelin for 45 min and partial block after pretreatment with Dynasore (open black; 0.1 mM in 1:500 DMSO, 30 min; flow cytometry). DMSO (1:500) alone has no effect on IkBa degradation or p38 phosphorylation (data not shown). (B-D) Representative graphs and heat maps from three independent experiments are shown. (E) Transient increase in p38 MAPK phosphorylation after myelin exposure demonstrated by western blot. 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{"pdf_hash": "608ce2d877b8b95251bac50b4e4a1f02088292da", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. The evaluation methods of radiation brain necrosis. (A) The area of the edema at one layer of the MRI image. (B) The outer edge of radiation necrosis of the brain. (C) The inner edge of radiation necrosis of the brain. (D) Determination of MRI signal in brain necrosis area. (E) Determination of MRI signal in cerebral white matter area at the same level. The volume was calculated using the product of the area of the edema region and the slice thickness. The edema index (EI) was used for evaluation. The EI = Volume A/Volume B. The volume of cerebral necrosis was calculated using the subtraction of the inner diameter volume from the outer diameter volume of the enhancement region of cerebral necrosis(Volume B subtract Volume C). The changes in information in the region of cerebral necrosis used the measurement of the T1 strengthening phase. Three areas in the strengthening region of cerebral necrosis were selected to measure the signal values and to calculate the mean value; in addition, the value was compared with the white matter signal value of the same MRI to eliminate the influences of different strengthening degrees; this ratio was used to measure the changes in signals in the regions of cerebral necrosis before and after treatment.", "width": 480, "height": 1544, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "c": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "d": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "e": [65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81]}, "subfigures": [{"id": "9ce76f33-c612-414a-8599-c04d47a85525", "label": "a", "points": [[9, 6.8], [9, 296.8], [472, 296.8], [472, 6.8]], "color": "yellow"}, {"id": "0c0b80a4-9c33-4a2f-b836-35e0d3608ccf", "label": "b", "points": 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A) CT slice images and doses for pre-SABT plan; B) CT slice images and doses for SABT plan; C) Three-dimensional map; D) Dose profile of the purple line for retrospective analysis of SABT plan; E) Dose profile of the red line for virtual SBRT plan", "width": 630, "height": 1276, "subcaptions": {"a": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "c": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "e": [57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "5346156b-b29e-4096-90ce-704106ae74f8", "label": "a", "points": [[1.5, 4], [1.5, 477], [628.5, 477], [628.5, 4]], "color": "yellow"}, {"id": "2b21bea5-00a5-451b-a147-c77ad434f848", "label": "c", "points": [[2.5, 508], [2.5, 941], [627.5, 941], [627.5, 508]], "color": "cyan"}, {"id": "937d5ecc-7959-4b3c-89df-47d658940dd2", "label": "e", "points": [[4.5, 973], [4.5, 1274], [629.5, 1274], [629.5, 973]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, 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{"pdf_hash": "6d7a140e7fe4055a6db9e2a679c369618b41a64d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Summary of clinical and diagnostic features. At initial visit, color fundus photography (A) and fundus f luorescein angiography (A) showed normal appearance. However, fundus autofluorescence (FAF) imaging (C) and spectral-domain optical coherence tomography (SD-OCT) (D) showed hyperfluorescence and diffuse disruption of the photoreceptor inner segment-outer segment (IS-OS) junction line (white arrowheads indicate the border of the irregular photoreceptor IS-OS junction area) in the centermost area and inferior retinal areas of macula corresponding to the area of reduced amplitudes in the multifocal electroretinography (ERG) (E). Humphrey visual field (HVF) perimetry showed that the visual field defects corresponded to SD-OCT, FAF imaging, and multifocal ERG (F). Although the photoreceptor disruption was partially restored at 3 months after treatment (G), the disruption became aggravated gradually thereafter (H), at 5 months after treatment (I), at 6 months after treatment. (J) One month after antimicrobial treatment with penicillin, restoration of the photoreceptor IS-OS junction occurred, and vision was restored to 20 / 30 in right eye. Three months after antimicrobial therapy, vision improved to 20 / 20 in right eye and SD-OCT revealed complete restoration of the photoreceptor IS-OS junction (K). 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{"pdf_hash": "8e66bc7572bba677024a15af2b5618a4c4f9e063", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Left: MRI of the orbits. Coronal, T2-weighted MR image demonstrates an ovoid mass-like lesion with high signal intensity, corresponding to lung cancer metastasis. The lesion provokes a globe displacement (arrow). Right: photograph of the patient.", "width": 938, "height": 374, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "b": [44, 45, 46, 47, 48, 49, 50]}, "subfigures": [{"id": "613e6c59-091a-402d-8a4b-a6645f39320d", "label": "a", "points": [[1.5, 370.5], [1.5, 4.4], [432.7, 4.4], [432.7, 370.5]], "color": "yellow"}, {"id": "a2f96db7-da66-4855-9bc3-00a422be055c", "label": "b", "points": [[438.6, 4.4], [438.6, 370.5], [935.1, 370.5], [935.1, 4.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Left", "start": 8, "end": 12, "id": 4}, {"text": ":", "start": 12, "end": 13, "id": 5}, {"text": "MRI", "start": 14, "end": 17, "id": 6}, {"text": "of", "start": 18, "end": 20, "id": 7}, {"text": "the", "start": 21, "end": 24, "id": 8}, {"text": "orbits", "start": 25, "end": 31, "id": 9}, {"text": ".", "start": 31, "end": 32, "id": 10}, {"text": "Coronal", "start": 33, "end": 40, "id": 11}, {"text": ",", "start": 40, "end": 41, "id": 12}, {"text": "T2-weighted", "start": 42, "end": 53, "id": 13}, {"text": "MR", "start": 54, "end": 56, "id": 14}, {"text": "image", "start": 57, "end": 62, "id": 15}, {"text": "demonstrates", "start": 63, "end": 75, "id": 16}, {"text": "an", "start": 76, "end": 78, "id": 17}, {"text": "ovoid", "start": 79, "end": 84, "id": 18}, {"text": "mass", "start": 85, "end": 89, "id": 19}, {"text": "-", "start": 89, "end": 90, "id": 20}, {"text": "like", "start": 90, "end": 94, "id": 21}, {"text": "lesion", "start": 95, "end": 101, "id": 22}, {"text": "with", "start": 102, "end": 106, "id": 23}, {"text": "high", "start": 107, "end": 111, "id": 24}, {"text": "signal", "start": 112, "end": 118, "id": 25}, {"text": "intensity", "start": 119, "end": 128, "id": 26}, {"text": ",", "start": 128, "end": 129, "id": 27}, {"text": "corresponding", "start": 130, "end": 143, "id": 28}, {"text": "to", "start": 144, "end": 146, "id": 29}, {"text": "lung", "start": 147, "end": 151, "id": 30}, {"text": "cancer", "start": 152, "end": 158, "id": 31}, {"text": "metastasis", "start": 159, "end": 169, "id": 32}, {"text": ".", "start": 169, "end": 170, "id": 33}, {"text": "The", "start": 171, "end": 174, "id": 34}, {"text": "lesion", "start": 175, "end": 181, "id": 35}, {"text": "provokes", "start": 182, "end": 190, "id": 36}, {"text": "a", "start": 191, "end": 192, "id": 37}, {"text": "globe", "start": 193, "end": 198, "id": 38}, {"text": "displacement", "start": 199, "end": 211, "id": 39}, {"text": "(", "start": 212, "end": 213, "id": 40}, {"text": "arrow", "start": 213, "end": 218, "id": 41}, {"text": ")", "start": 218, "end": 219, "id": 42}, {"text": ".", "start": 219, "end": 220, "id": 43}, {"text": "Right", "start": 221, "end": 226, "id": 44}, {"text": ":", "start": 226, "end": 227, "id": 45}, {"text": "photograph", "start": 228, "end": 238, "id": 46}, {"text": "of", "start": 239, "end": 241, "id": 47}, {"text": "the", "start": 242, "end": 245, "id": 48}, {"text": "patient", "start": 246, "end": 253, "id": 49}, {"text": ".", "start": 253, "end": 254, "id": 50}]}
{"pdf_hash": "a2c648039a0ab2466560c400b5c73548965b2584", "fig_key": "Figure8", "fig_uri": "9-Figure8-1.png", "text": "Figure 8. Morphology and skin sterol content of control and Epi-Insig-DKO mice at 3 and 5.5 months after stopping simvastatin. (a, b) Five Epi-Insig-DKO mice were treated daily with 1 mg simvastatin from postnatal day (PND) 2 to PND 13. Thereafter, the mice were left untreated for 5.5 months. These photographs show the same Epi-Insig DKO mouse at 3.5 months (a) and 6 months (b) of age. The loss of hair and decrease in body weight that occurred in this mouse between 3.5 and 6 months of age was reproduced in all five mutant mice studied in this experiment. (c-h) The sterol content in the back skin from control and Epi-Insig-DKO mice at 6 months was measured by gas chromatography-mass spectroscopy. Each bar represents the mean \u00b1 SEM of data from five mice. 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{"pdf_hash": "28b96604e7bb67268ffe13955a58d665543e9f74", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 Blunt cerebrovascular occlusion (grade IV lesions according to the Biffl classification). a, b A 51-year-old man who had suffered a motorcycle accident. The axial MPR image (a) (3-mm thickness) shows the absence of contrast material within the right vertebral artery (arrow) and the coexistence of a C4 lateral mass fracture (arrowhead) involving the right vertebral channel; the same findings (arrows and arrowhead) are clearly detectable on the sagittal MPR image on which the presence of contrast material is detectable within the right vertebral artery upstream and downstream the occlusion. 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{"pdf_hash": "89fbb1d301e03808795b116d4414779486c6c5fa", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Figure 6 Stanford type A dissection with direct communication between the true lumen and false lumens (arrows in A). The true lumen (T) was obviously narrowed due to compression by the false lumen (F) with thrombus formed in the false lumen as shown on the sagittal reformatted image (B). The intimal flap (short arrows in B) arises from the level of the left ventricle (long arrows in B); C: A protrusion sign was observed on virtual intravascular endoscopy (VIE) images; D, E: The long intimal tear was identified at the ascending aorta posterior to the protrusion from the false lumen on different VIE visualizations. 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{"pdf_hash": "575a6e984c43aefcddb3188f19776533daeb0385", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Case 1. The chest CT reported an intraluminal polypoid lesion dependent on the cervical esophagus. Panendoscopy revealed a polypoid lesion with a long pedicle. Endoscopic ultrasound showed a hypoechogenic lesion dependent on the muscularis propria layer. The surgical specimen reported IFP.", "width": 1134, "height": 822, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "c": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "d": [42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "7c7c2e7b-3030-46c3-a2c3-eedae736118e", "label": "a", "points": [[7.5, 4.2], [7.5, 459.2], [596.9, 459.2], [596.9, 4.2]], "color": "yellow"}, {"id": "09d09c45-ceef-4448-a070-b444abb7361c", "label": "b", "points": [[600.5, 9.6], [600.5, 453.8], [1127.2, 453.8], [1127.2, 9.6]], "color": "cyan"}, {"id": "83d2215b-f077-452c-b639-7df102bfbbf4", "label": "c", "points": [[7.5, 468.2], [7.5, 790.6], [439.2, 790.6], [439.2, 468.2]], "color": "magenta"}, {"id": "31fe4747-e849-4f91-b9d5-82bf07dafa84", "label": "d", "points": [[446.4, 473.6], [446.4, 788.9], [1125.4, 788.9], [1125.4, 473.6]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Case", "start": 9, "end": 13, "id": 2}, {"text": "1", "start": 14, "end": 15, "id": 3}, {"text": ".", "start": 15, "end": 16, "id": 4}, {"text": "The", "start": 17, "end": 20, "id": 5}, {"text": "chest", "start": 21, "end": 26, "id": 6}, {"text": "CT", "start": 27, "end": 29, "id": 7}, {"text": "reported", "start": 30, "end": 38, "id": 8}, {"text": "an", "start": 39, "end": 41, "id": 9}, {"text": "intraluminal", "start": 42, "end": 54, "id": 10}, {"text": "polypoid", "start": 55, "end": 63, "id": 11}, {"text": "lesion", "start": 64, "end": 70, "id": 12}, {"text": "dependent", "start": 71, "end": 80, "id": 13}, {"text": "on", "start": 81, "end": 83, "id": 14}, {"text": "the", "start": 84, "end": 87, "id": 15}, {"text": "cervical", "start": 88, "end": 96, "id": 16}, {"text": "esophagus", "start": 97, "end": 106, "id": 17}, {"text": ".", "start": 106, "end": 107, "id": 18}, {"text": "Panendoscopy", "start": 108, "end": 120, "id": 19}, {"text": "revealed", "start": 121, "end": 129, "id": 20}, {"text": "a", "start": 130, "end": 131, "id": 21}, {"text": "polypoid", "start": 132, "end": 140, "id": 22}, {"text": "lesion", "start": 141, "end": 147, "id": 23}, {"text": "with", "start": 148, "end": 152, "id": 24}, {"text": "a", "start": 153, "end": 154, "id": 25}, {"text": "long", "start": 155, "end": 159, "id": 26}, {"text": "pedicle", "start": 160, "end": 167, "id": 27}, {"text": ".", "start": 167, "end": 168, "id": 28}, {"text": "Endoscopic", "start": 169, "end": 179, "id": 29}, {"text": "ultrasound", "start": 180, "end": 190, "id": 30}, {"text": "showed", "start": 191, "end": 197, "id": 31}, {"text": "a", "start": 198, "end": 199, "id": 32}, {"text": "hypoechogenic", "start": 200, "end": 213, "id": 33}, {"text": "lesion", "start": 214, "end": 220, "id": 34}, {"text": "dependent", "start": 221, "end": 230, "id": 35}, {"text": "on", "start": 231, "end": 233, "id": 36}, {"text": "the", "start": 234, "end": 237, "id": 37}, {"text": "muscularis", "start": 238, "end": 248, "id": 38}, {"text": "propria", "start": 249, "end": 256, "id": 39}, {"text": "layer", "start": 257, "end": 262, "id": 40}, {"text": ".", "start": 262, "end": 263, "id": 41}, {"text": "The", "start": 264, "end": 267, "id": 42}, {"text": "surgical", "start": 268, "end": 276, "id": 43}, {"text": "specimen", "start": 277, "end": 285, "id": 44}, {"text": "reported", "start": 286, "end": 294, "id": 45}, {"text": "IFP", "start": 295, "end": 298, "id": 46}, {"text": ".", "start": 298, "end": 299, "id": 47}]}
{"pdf_hash": "e4d55132c4408c51863b8d958dea803760dc1259", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4 - Axial (top row) and coronal (bottom row) CT sections without contrast through orbits show remarkable resolution of the ill-defined soft tissue thickening around the lateral aspects of the left orbit in the axial (top row figures 1-3) and coronal (bottom row figures 4-6).", "width": 650, "height": 404, "subcaptions": {"a": [3, 4, 5, 6, 7, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "b": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "f20dd95e-58e0-4c05-ac5d-04a742845913", "label": "a", "points": [[2.6, 0], [2.6, 207.4], [643.3, 207.4], [643.3, 0]], "color": "yellow"}, {"id": "5640c2e4-fc2e-4483-9d79-3b90182a8648", "label": "b", "points": [[4.6, 210.5], [4.6, 367.6], [649.5, 367.6], [649.5, 210.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "-", "start": 9, "end": 10, "id": 2}, {"text": "Axial", "start": 11, "end": 16, "id": 3}, {"text": "(", "start": 17, "end": 18, "id": 4}, {"text": "top", "start": 18, "end": 21, "id": 5}, {"text": "row", "start": 22, "end": 25, "id": 6}, {"text": ")", "start": 25, "end": 26, "id": 7}, {"text": "and", "start": 27, "end": 30, "id": 8}, {"text": "coronal", "start": 31, "end": 38, "id": 9}, {"text": "(", "start": 39, "end": 40, "id": 10}, {"text": "bottom", "start": 40, "end": 46, "id": 11}, {"text": "row", "start": 47, "end": 50, "id": 12}, {"text": ")", "start": 50, "end": 51, "id": 13}, {"text": "CT", "start": 52, "end": 54, "id": 14}, {"text": "sections", "start": 55, "end": 63, "id": 15}, {"text": "without", "start": 64, "end": 71, "id": 16}, {"text": "contrast", "start": 72, "end": 80, "id": 17}, {"text": "through", "start": 81, "end": 88, "id": 18}, {"text": "orbits", "start": 89, "end": 95, "id": 19}, {"text": "show", "start": 96, "end": 100, "id": 20}, {"text": "remarkable", "start": 101, "end": 111, "id": 21}, {"text": "resolution", "start": 112, "end": 122, "id": 22}, {"text": "of", "start": 123, "end": 125, "id": 23}, {"text": "the", "start": 126, "end": 129, "id": 24}, {"text": "ill", "start": 130, "end": 133, "id": 25}, {"text": "-", "start": 133, "end": 134, "id": 26}, {"text": "defined", "start": 134, "end": 141, "id": 27}, {"text": "soft", "start": 142, "end": 146, "id": 28}, {"text": "tissue", "start": 147, "end": 153, "id": 29}, {"text": "thickening", "start": 154, "end": 164, "id": 30}, {"text": "around", "start": 165, "end": 171, "id": 31}, {"text": "the", "start": 172, "end": 175, "id": 32}, {"text": "lateral", "start": 176, "end": 183, "id": 33}, {"text": "aspects", "start": 184, "end": 191, "id": 34}, {"text": "of", "start": 192, "end": 194, "id": 35}, {"text": "the", "start": 195, "end": 198, "id": 36}, {"text": "left", "start": 199, "end": 203, "id": 37}, {"text": "orbit", "start": 204, "end": 209, "id": 38}, {"text": "in", "start": 210, "end": 212, "id": 39}, {"text": "the", "start": 213, "end": 216, "id": 40}, {"text": "axial", "start": 217, "end": 222, "id": 41}, {"text": "(", "start": 223, "end": 224, "id": 42}, {"text": "top", "start": 224, "end": 227, "id": 43}, {"text": "row", "start": 228, "end": 231, "id": 44}, {"text": "figures", "start": 232, "end": 239, "id": 45}, {"text": "1", "start": 240, "end": 241, "id": 46}, {"text": "-", "start": 241, "end": 242, "id": 47}, {"text": "3", "start": 242, "end": 243, "id": 48}, {"text": ")", "start": 243, "end": 244, "id": 49}, {"text": "and", "start": 245, "end": 248, "id": 50}, {"text": "coronal", "start": 249, "end": 256, "id": 51}, {"text": "(", "start": 257, "end": 258, "id": 52}, {"text": "bottom", "start": 258, "end": 264, "id": 53}, {"text": "row", "start": 265, "end": 268, "id": 54}, {"text": "figures", "start": 269, "end": 276, "id": 55}, {"text": "4", "start": 277, "end": 278, "id": 56}, {"text": "-", "start": 278, "end": 279, "id": 57}, {"text": "6", "start": 279, "end": 280, "id": 58}, {"text": ")", "start": 280, "end": 281, "id": 59}, {"text": ".", "start": 281, "end": 282, "id": 60}]}
{"pdf_hash": "13b1618183560924dbf2fa03b17dbae0fa293bc3", "fig_key": "Figure1", "fig_uri": "22-Figure1-1.png", "text": "Figure 1 MRI at presentation. Axial (A) and sagittal (B) fast spin-echo T2-weighted sequence show a large fluid filled urethral diverticulum (*) displacing the urethra (U) anteriorly. Heterogeneous low T2 signal in the anterior portion (arrows).", "width": 1052, "height": 536, "subcaptions": {"a": [6, 7, 8, 9, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "b7898132-e49b-47c6-bf11-527049cca592", "label": "a", "points": [[6.9, 6.8], [6.9, 525.3], [512.1, 525.3], [512.1, 6.8]], "color": "yellow"}, {"id": "a876b745-e212-4555-98d1-dac1f4f66082", "label": "b", "points": [[528.7, 5.1], [528.7, 513.7], [1030.6, 513.7], [1030.6, 5.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "MRI", "start": 9, "end": 12, "id": 2}, {"text": "at", "start": 13, "end": 15, "id": 3}, {"text": "presentation", "start": 16, "end": 28, "id": 4}, {"text": ".", "start": 28, "end": 29, "id": 5}, {"text": "Axial", "start": 30, "end": 35, "id": 6}, {"text": "(", "start": 36, "end": 37, "id": 7}, {"text": "A", "start": 37, "end": 38, "id": 8}, {"text": ")", "start": 38, "end": 39, "id": 9}, {"text": "and", "start": 40, "end": 43, "id": 10}, {"text": "sagittal", "start": 44, "end": 52, "id": 11}, {"text": "(", "start": 53, "end": 54, "id": 12}, {"text": "B", "start": 54, "end": 55, "id": 13}, {"text": ")", "start": 55, "end": 56, "id": 14}, {"text": "fast", "start": 57, "end": 61, "id": 15}, {"text": "spin", "start": 62, "end": 66, "id": 16}, {"text": "-", "start": 66, "end": 67, "id": 17}, {"text": "echo", "start": 67, "end": 71, "id": 18}, {"text": "T2-weighted", "start": 72, "end": 83, "id": 19}, {"text": "sequence", "start": 84, "end": 92, "id": 20}, {"text": "show", "start": 93, "end": 97, "id": 21}, {"text": "a", "start": 98, "end": 99, "id": 22}, {"text": "large", "start": 100, "end": 105, "id": 23}, {"text": "fluid", "start": 106, "end": 111, "id": 24}, {"text": "filled", "start": 112, "end": 118, "id": 25}, {"text": "urethral", "start": 119, "end": 127, "id": 26}, {"text": "diverticulum", "start": 128, "end": 140, "id": 27}, {"text": "(", "start": 141, "end": 142, "id": 28}, {"text": "*", "start": 142, "end": 143, "id": 29}, {"text": ")", "start": 143, "end": 144, "id": 30}, {"text": "displacing", "start": 145, "end": 155, "id": 31}, {"text": "the", "start": 156, "end": 159, "id": 32}, {"text": "urethra", "start": 160, "end": 167, "id": 33}, {"text": "(", "start": 168, "end": 169, "id": 34}, {"text": "U", "start": 169, "end": 170, "id": 35}, {"text": ")", "start": 170, "end": 171, "id": 36}, {"text": "anteriorly", "start": 172, "end": 182, "id": 37}, {"text": ".", "start": 182, "end": 183, "id": 38}, {"text": "Heterogeneous", "start": 184, "end": 197, "id": 39}, {"text": "low", "start": 198, "end": 201, "id": 40}, {"text": "T2", "start": 202, "end": 204, "id": 41}, {"text": "signal", "start": 205, "end": 211, "id": 42}, {"text": "in", "start": 212, "end": 214, "id": 43}, {"text": "the", "start": 215, "end": 218, "id": 44}, {"text": "anterior", "start": 219, "end": 227, "id": 45}, {"text": "portion", "start": 228, "end": 235, "id": 46}, {"text": "(", "start": 236, "end": 237, "id": 47}, {"text": "arrows", "start": 237, "end": 243, "id": 48}, {"text": ")", "start": 243, "end": 244, "id": 49}, {"text": ".", "start": 244, "end": 245, "id": 50}]}
{"pdf_hash": "5760334c036ed99432de82f3479d1b0bdba83af0", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3 Initial MRI studies of patient number four. a Sagittal MRI showing the involvement of vertebral body (Th 11) and thecal sac compression. b Axial MRI demonstrating the destruction of both pedicles and the ventral tumor circumference", "width": 1016, "height": 532, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "9bc21498-7729-4c12-ac24-aa8fa6224e9c", "label": "a", "points": [[0.3, 4.3], [0.3, 525.9], [441.7, 525.9], [441.7, 4.3]], "color": "yellow"}, {"id": "0bada25a-dfa4-47af-b108-c02a2ecbf0c3", "label": "b", "points": [[457.7, 5.9], [457.7, 525.9], [1013.1, 525.9], [1013.1, 5.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Initial", "start": 7, "end": 14, "id": 3}, {"text": "MRI", "start": 15, "end": 18, "id": 4}, {"text": "studies", "start": 19, "end": 26, "id": 5}, {"text": "of", "start": 27, "end": 29, "id": 6}, {"text": "patient", "start": 30, "end": 37, "id": 7}, {"text": "number", "start": 38, "end": 44, "id": 8}, {"text": "four", "start": 45, "end": 49, "id": 9}, {"text": ".", "start": 49, "end": 50, "id": 10}, {"text": "a", "start": 51, "end": 52, "id": 11}, {"text": "Sagittal", "start": 53, "end": 61, "id": 12}, {"text": "MRI", "start": 62, "end": 65, "id": 13}, {"text": "showing", "start": 66, "end": 73, "id": 14}, {"text": "the", "start": 74, "end": 77, "id": 15}, {"text": "involvement", "start": 78, "end": 89, "id": 16}, {"text": "of", "start": 90, "end": 92, "id": 17}, {"text": "vertebral", "start": 93, "end": 102, "id": 18}, {"text": "body", "start": 103, "end": 107, "id": 19}, {"text": "(", "start": 108, "end": 109, "id": 20}, {"text": "Th", "start": 109, "end": 111, "id": 21}, {"text": "11", "start": 112, "end": 114, "id": 22}, {"text": ")", "start": 114, "end": 115, "id": 23}, {"text": "and", "start": 116, "end": 119, "id": 24}, {"text": "thecal", "start": 120, "end": 126, "id": 25}, {"text": "sac", "start": 127, "end": 130, "id": 26}, {"text": "compression", "start": 131, "end": 142, "id": 27}, {"text": ".", "start": 142, "end": 143, "id": 28}, {"text": "b", "start": 144, "end": 145, "id": 29}, {"text": "Axial", "start": 146, "end": 151, "id": 30}, {"text": "MRI", "start": 152, "end": 155, "id": 31}, {"text": "demonstrating", "start": 156, "end": 169, "id": 32}, {"text": "the", "start": 170, "end": 173, "id": 33}, {"text": "destruction", "start": 174, "end": 185, "id": 34}, {"text": "of", "start": 186, "end": 188, "id": 35}, {"text": "both", "start": 189, "end": 193, "id": 36}, {"text": "pedicles", "start": 194, "end": 202, "id": 37}, {"text": "and", "start": 203, "end": 206, "id": 38}, {"text": "the", "start": 207, "end": 210, "id": 39}, {"text": "ventral", "start": 211, "end": 218, "id": 40}, {"text": "tumor", "start": 219, "end": 224, "id": 41}, {"text": "circumference", "start": 225, "end": 238, "id": 42}]}
{"pdf_hash": "73f52899e33fdb955dd1e08716a0edf2d236f942", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5 Representative transmission electron micrographs. (A) Untreated cell before dark cultivation (control) and the cells that had been heat treated and then cultured in the dark for (B) 0, (C) 2, (D) 6, (E) 12, (F) 24, (G) 48 and (H) 72 h, respectively. Bars = 1 \u03bcm. Abbreviations: c, chloroplast; m, mitochondrion; n, nucleus; nl, nucleolus; s, starch granule; v, vacuole. Arrows in (B): condensation of chromatin on the inner side of the nuclear membrane. Arrows in (E-G): exudation of organic substances between the cell wall and the cell membrane. 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{"pdf_hash": "52448d86e3a4356160734fb8899e4b49880acc31", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 Glioblastoma with EGFR amplification (> 20 copies) and positive EGFRvIII transcript. Axial fluid-attenuated inversion recovery image (a), contrast-enhanced T1-weighted image (b), relative cerebral blood volume (rCBV) map overlaid on contrast T1-weighted image (c), and T2* time\u2013intensity curve (d) demonstrate increased perfusion", "width": 1370, "height": 386, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [28, 29, 30, 31, 32, 33, 34, 35], "c": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "d": [55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "6a5ed6a6-9463-41dc-b632-a36ff7ce89f8", "label": "a", "points": [[3.3, 1.8], [3.3, 380.5], [312.8, 380.5], [312.8, 1.8]], "color": "yellow"}, {"id": "6d0dcbfd-9aa8-4125-b73a-ee488bcb1bca", "label": "b", "points": [[330.1, -0.4], [330.1, 380.5], [646.1, 380.5], [646.1, -0.4]], "color": "cyan"}, {"id": "bc71873a-7a44-4802-9f9f-5fb1362cf300", "label": "c", "points": [[663.4, 6.1], [663.4, 378.4], [975, 378.4], [975, 6.1]], "color": "magenta"}, {"id": "e62d61b2-1d32-4849-85eb-98b5bf757acb", "label": "d", "points": [[988, 8.3], [988, 382.7], [1366.8, 382.7], [1366.8, 8.3]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Glioblastoma", "start": 7, "end": 19, "id": 3}, {"text": "with", "start": 20, "end": 24, "id": 4}, {"text": "EGFR", "start": 25, "end": 29, "id": 5}, {"text": "amplification", "start": 30, "end": 43, "id": 6}, {"text": "(", "start": 44, "end": 45, "id": 7}, {"text": ">", "start": 45, "end": 46, "id": 8}, {"text": "20", "start": 47, "end": 49, "id": 9}, {"text": "copies", "start": 50, "end": 56, "id": 10}, {"text": ")", "start": 56, "end": 57, "id": 11}, {"text": "and", "start": 58, "end": 61, "id": 12}, {"text": "positive", "start": 62, "end": 70, "id": 13}, {"text": "EGFRvIII", "start": 71, "end": 79, "id": 14}, {"text": "transcript", "start": 80, "end": 90, "id": 15}, {"text": ".", "start": 90, "end": 91, "id": 16}, {"text": "Axial", "start": 92, "end": 97, "id": 17}, {"text": "fluid", "start": 98, "end": 103, "id": 18}, {"text": "-", "start": 103, "end": 104, "id": 19}, {"text": "attenuated", "start": 104, "end": 114, "id": 20}, {"text": "inversion", "start": 115, "end": 124, "id": 21}, {"text": "recovery", "start": 125, "end": 133, "id": 22}, {"text": "image", "start": 134, "end": 139, "id": 23}, {"text": "(", "start": 140, "end": 141, "id": 24}, {"text": "a", "start": 141, "end": 142, "id": 25}, {"text": ")", "start": 142, "end": 143, "id": 26}, {"text": ",", "start": 143, "end": 144, "id": 27}, {"text": "contrast", "start": 145, "end": 153, "id": 28}, {"text": "-", "start": 153, "end": 154, "id": 29}, {"text": "enhanced", "start": 154, "end": 162, "id": 30}, {"text": "T1-weighted", "start": 163, "end": 174, "id": 31}, {"text": "image", "start": 175, "end": 180, "id": 32}, {"text": "(", "start": 181, "end": 182, "id": 33}, {"text": "b", "start": 182, "end": 183, "id": 34}, {"text": ")", "start": 183, "end": 184, "id": 35}, {"text": ",", "start": 184, "end": 185, "id": 36}, {"text": "relative", "start": 186, "end": 194, "id": 37}, {"text": "cerebral", "start": 195, "end": 203, "id": 38}, {"text": "blood", "start": 204, "end": 209, "id": 39}, {"text": "volume", "start": 210, "end": 216, "id": 40}, {"text": "(", "start": 217, "end": 218, "id": 41}, {"text": "rCBV", "start": 218, "end": 222, "id": 42}, {"text": ")", "start": 222, "end": 223, "id": 43}, {"text": "map", "start": 224, "end": 227, "id": 44}, {"text": "overlaid", "start": 228, "end": 236, "id": 45}, {"text": "on", "start": 237, "end": 239, "id": 46}, {"text": "contrast", "start": 240, "end": 248, "id": 47}, {"text": "T1-weighted", "start": 249, "end": 260, "id": 48}, {"text": "image", "start": 261, "end": 266, "id": 49}, {"text": "(", "start": 267, "end": 268, "id": 50}, {"text": "c", "start": 268, "end": 269, "id": 51}, {"text": ")", "start": 269, "end": 270, "id": 52}, {"text": ",", "start": 270, "end": 271, "id": 53}, {"text": "and", "start": 272, "end": 275, "id": 54}, {"text": "T2", "start": 276, "end": 278, "id": 55}, {"text": "*", "start": 278, "end": 279, "id": 56}, {"text": "time", "start": 280, "end": 284, "id": 57}, {"text": "\u2013", "start": 284, "end": 285, "id": 58}, {"text": "intensity", "start": 285, "end": 294, "id": 59}, {"text": "curve", "start": 295, "end": 300, "id": 60}, {"text": "(", "start": 301, "end": 302, "id": 61}, {"text": "d", "start": 302, "end": 303, "id": 62}, {"text": ")", "start": 303, "end": 304, "id": 63}, {"text": "demonstrate", "start": 305, "end": 316, "id": 64}, {"text": "increased", "start": 317, "end": 326, "id": 65}, {"text": "perfusion", "start": 327, "end": 336, "id": 66}]}
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{"pdf_hash": "9b3051b82f9840e8420dccd497b12677b3d8f338", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3: Histopathology. Fibrillar matrix with pleomorphic cells, some with gemistocytic appearance (arrow) (A), alternating with areas of spindle cells arranged in interlaced fascicles (B), and round cells with epithelioid appearance (C), with mitosis figures (arrows), as well as others with nuclear atypia and pseudointranuclear inclusions (arrowhead) (D). Hematoxylin and eosin staining, \u00d740.", "width": 1150, "height": 852, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "c": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "d": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "5d6f49c3-cfe2-47f9-9e68-6e270f6d2217", "label": "a", "points": [[37.2, 1.8], [37.2, 405.1], [573.2, 405.1], [573.2, 1.8]], "color": "yellow"}, {"id": "f447b1a4-2319-410b-af52-ce2297b7d37b", "label": "b", "points": [[582.3, 3.6], [582.3, 410.6], [1114.6, 410.6], [1114.6, 3.6]], "color": "cyan"}, {"id": "5c307083-1de9-4d56-a81e-426d2a54c140", "label": "c", "points": [[37.2, 412.4], [37.2, 812.1], [571.4, 812.1], [571.4, 412.4]], "color": "magenta"}, {"id": "b7393ba2-617e-4be2-9d30-5ee63c8d08fd", "label": "d", "points": [[582.3, 414.2], [582.3, 821.2], [1118.2, 821.2], [1118.2, 414.2]], "color": 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{"pdf_hash": "9fafb344d65cec844b631f4c7bc9fef2873dd896", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. Computed tomographic (CT) images of the liver of a 64-year-old man with Child -Pugh Grade A who presented with a PVTT in the left first branch. (A) Portal-dominant phase dynamic CT images before HAI therapy showing the dilation of the left first branch of the portal vein and the tumor thrombosis (arrow). (B) Recanalization of the portal vein that had been obstructed by the tumor thrombosis was observed after three HAI treatment sessions (arrow).", "width": 958, "height": 386, "subcaptions": {"a": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "b": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93]}, "subfigures": [{"id": "b49e0176-4d17-45a1-8de2-3ed6a27e3023", "label": "a", "points": [[16.9, 3.5], [16.9, 357.7], [442.2, 357.7], [442.2, 3.5]], "color": "yellow"}, {"id": "69d674d9-da0d-4c63-b14b-b9589c03cf6f", "label": "b", "points": [[490.6, 9.6], [490.6, 353.1], [934.1, 353.1], [934.1, 9.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomographic", 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{"pdf_hash": "decbfd00d446e3e8cacb55f09366c3633a6d4333", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig 1. Detection of significant residual stenosis. (A) Multidetector row computed tomography (MDCT) shows significant residual stenosis in segment 6 (arrow) after thrombolysis. Conventional coronary angiography (CCAG) shows the lesion in the same segment (arrow). (B) Significant residual stenosis in segment 2 (arrow) on MDCT. CCAG shows the same result (arrow). (C) Multiple significant residual stenoses in segment 12 (arrows) detected by MDCT and CCAG. The lesions on MDCT appear more severe than on CCAG; both meet the definition of significant residual stenosis in this study (stenosis \u226550% including total occlusion of vessels). 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{"pdf_hash": "e897ce0e9567b78cb6d6777ccb15105e202c035b", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Abdominal X-ray before and after the positioning of the third stent. 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{"pdf_hash": "b85c1b459fcd33caba6d7c41d608d02958f35266", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Clinical and radiological feature. A. Intraoral photograph. Despite the presence of right mandibular swelling, there was no specific finding in the intraoral findings. B. Panoramic view. It was difficult to locate specific findings on panoramic examination. C, D. Osteolytic findings were observed on computed tomography (CT), including a well-defined, buccolingual expansile lesion (C: axial view, D: coronal view). Profuse periosteal reaction was also observed around the lesion. Dae-Seok Hwang et al: Langerhans cell histiocytosis of the mandible: two case reports and literature review. 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{"pdf_hash": "d3c56f93a0a90bef640e9769ff8e5427a688f88d", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. (A) Computed tomography thorax (axial view, soft tissue window). A heterogeneous mass at the apico-posterior segment of the left upper lobe of the left lung abutting the posterior wall of the aortic arch (white arrow). (B) The mass adjacent to the descending aorta during endoscopic ultrasound using an echobronchoscope (EUS-B) examination. (C) Real-time endoscopic ultrasound with bronchoscope-guided fine-needle aspiration performed with 22G transbronchial needle aspiration into the mass (white arrow). 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{"pdf_hash": "875ab8077f5972878a6392fe14ffac185753eeea", "fig_key": "Figure9", "fig_uri": "9-Figure9-1.png", "text": "Fig. 9a, b Right hemidiaphragm rupture with hump and band sign. a Right lateral and b posterior perspective volume rendered CT images in blunt trauma patient show hump-shaped liver tissue projecting above plane of diaphragm with low attenuation band across base of hump (arrows) at level of diaphragm tear", "width": 678, "height": 1386, "subcaptions": {"a": [15, 16, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "171f6918-f7fe-44ce-b171-25b6484f6635", "label": "a", "points": [[3.4, 58.9], [3.4, 793.7], [677.1, 793.7], [677.1, 58.9]], "color": "yellow"}, {"id": "ea64007f-0d40-4675-8c10-734c436594ff", "label": "b", "points": [[7.7, 801.2], [7.7, 1353.9], [673.9, 1353.9], [673.9, 801.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "9a", "start": 5, "end": 7, "id": 2}, {"text": ",", "start": 7, "end": 8, "id": 3}, {"text": "b", "start": 9, "end": 10, "id": 4}, {"text": "Right", "start": 11, "end": 16, "id": 5}, {"text": "hemidiaphragm", "start": 17, "end": 30, "id": 6}, {"text": "rupture", "start": 31, "end": 38, "id": 7}, {"text": "with", "start": 39, "end": 43, "id": 8}, {"text": "hump", "start": 44, "end": 48, "id": 9}, {"text": "and", "start": 49, "end": 52, "id": 10}, {"text": "band", "start": 53, "end": 57, "id": 11}, {"text": "sign", "start": 58, "end": 62, "id": 12}, {"text": ".", "start": 62, "end": 63, "id": 13}, {"text": "a", "start": 64, "end": 65, "id": 14}, {"text": "Right", "start": 66, "end": 71, "id": 15}, {"text": "lateral", "start": 72, "end": 79, "id": 16}, {"text": "and", "start": 80, "end": 83, "id": 17}, {"text": "b", "start": 84, "end": 85, "id": 18}, {"text": "posterior", "start": 86, "end": 95, "id": 19}, {"text": "perspective", "start": 96, "end": 107, "id": 20}, {"text": "volume", "start": 108, "end": 114, "id": 21}, {"text": "rendered", "start": 115, "end": 123, "id": 22}, {"text": "CT", "start": 124, "end": 126, "id": 23}, {"text": "images", "start": 127, "end": 133, "id": 24}, {"text": "in", "start": 134, "end": 136, "id": 25}, {"text": "blunt", "start": 137, "end": 142, "id": 26}, {"text": "trauma", "start": 143, "end": 149, "id": 27}, {"text": "patient", "start": 150, "end": 157, "id": 28}, {"text": "show", "start": 158, "end": 162, "id": 29}, {"text": "hump", "start": 163, "end": 167, "id": 30}, {"text": "-", "start": 167, "end": 168, "id": 31}, {"text": "shaped", "start": 168, "end": 174, "id": 32}, {"text": "liver", "start": 175, "end": 180, "id": 33}, {"text": "tissue", "start": 181, "end": 187, "id": 34}, {"text": "projecting", "start": 188, "end": 198, "id": 35}, {"text": "above", "start": 199, "end": 204, "id": 36}, {"text": "plane", "start": 205, "end": 210, "id": 37}, {"text": "of", "start": 211, "end": 213, "id": 38}, {"text": "diaphragm", "start": 214, "end": 223, "id": 39}, {"text": "with", "start": 224, "end": 228, "id": 40}, {"text": "low", "start": 229, "end": 232, "id": 41}, {"text": "attenuation", "start": 233, "end": 244, "id": 42}, {"text": "band", "start": 245, "end": 249, "id": 43}, {"text": "across", "start": 250, "end": 256, "id": 44}, {"text": "base", "start": 257, "end": 261, "id": 45}, {"text": "of", "start": 262, "end": 264, "id": 46}, {"text": "hump", "start": 265, "end": 269, "id": 47}, {"text": "(", "start": 270, "end": 271, "id": 48}, {"text": "arrows", "start": 271, "end": 277, "id": 49}, {"text": ")", "start": 277, "end": 278, "id": 50}, {"text": "at", "start": 279, "end": 281, "id": 51}, {"text": "level", "start": 282, "end": 287, "id": 52}, {"text": "of", "start": 288, "end": 290, "id": 53}, {"text": "diaphragm", "start": 291, "end": 300, "id": 54}, {"text": "tear", "start": 301, "end": 305, "id": 55}]}
{"pdf_hash": "aa79375ecd8eed6a0cff157182ee3e0e27343155", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 (a) Axial T2-weighted image showing a mass with relatively homogenous hypointensity located behind the right globe to the orbital apex. (b) Axial gadolinium-enhanced T1-weighted image showing homogenous enhancement.", "width": 942, "height": 358, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "32971e96-e868-4b33-8569-521a8506605a", "label": "a", "points": [[36.5, 1.5], [36.5, 321.4], [460.6, 321.4], [460.6, 1.5]], "color": "yellow"}, {"id": "3862ae20-5580-4208-a734-82aad19377bf", "label": "b", "points": [[479.9, 1.5], [479.9, 325.9], [907, 325.9], [907, 1.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Axial", "start": 13, "end": 18, "id": 5}, {"text": "T2-weighted", "start": 19, "end": 30, "id": 6}, {"text": "image", "start": 31, "end": 36, "id": 7}, {"text": "showing", "start": 37, "end": 44, "id": 8}, {"text": "a", "start": 45, "end": 46, "id": 9}, {"text": "mass", "start": 47, "end": 51, "id": 10}, {"text": "with", "start": 52, "end": 56, "id": 11}, {"text": "relatively", "start": 57, "end": 67, "id": 12}, {"text": "homogenous", "start": 68, "end": 78, "id": 13}, {"text": "hypointensity", "start": 79, "end": 92, "id": 14}, {"text": "located", "start": 93, "end": 100, "id": 15}, {"text": "behind", "start": 101, "end": 107, "id": 16}, {"text": "the", "start": 108, "end": 111, "id": 17}, {"text": "right", "start": 112, "end": 117, "id": 18}, {"text": "globe", "start": 118, "end": 123, "id": 19}, {"text": "to", "start": 124, "end": 126, "id": 20}, {"text": "the", "start": 127, "end": 130, "id": 21}, {"text": "orbital", "start": 131, "end": 138, "id": 22}, {"text": "apex", "start": 139, "end": 143, "id": 23}, {"text": ".", "start": 143, "end": 144, "id": 24}, {"text": "(", "start": 145, "end": 146, "id": 25}, {"text": "b", "start": 146, "end": 147, "id": 26}, {"text": ")", "start": 147, "end": 148, "id": 27}, {"text": "Axial", "start": 149, "end": 154, "id": 28}, {"text": "gadolinium", "start": 155, "end": 165, "id": 29}, {"text": "-", "start": 165, "end": 166, "id": 30}, {"text": "enhanced", "start": 166, "end": 174, "id": 31}, {"text": "T1-weighted", "start": 175, "end": 186, "id": 32}, {"text": "image", "start": 187, "end": 192, "id": 33}, {"text": "showing", "start": 193, "end": 200, "id": 34}, {"text": "homogenous", "start": 201, "end": 211, "id": 35}, {"text": "enhancement", "start": 212, "end": 223, "id": 36}, {"text": ".", "start": 223, "end": 224, "id": 37}]}
{"pdf_hash": "e7f9a4c72afa88ff3e1bc15e898c4907dbd4daa2", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Plain chest computed tomography (CT) of a 56\u2011year\u2011old male with a pulmonary inflammatory myofibroblastic tumor. (A) Lung window setting revealing an ill\u2011defined, sub\u2011pleural mass in the peripheral parenchyma of the right lower lobe, associated with cavity and air bronchogram. The coronal CT scan in (B) the mediastinum window setting revealing the irregularly\u2011shaped lesion. Contrast\u2011enhanced CT scan in (C) the arterial phase and (D) the venous phase revealing the lesion with high contrast enhancement. (E) Single\u2011photon emission computed tomography bone scan revealing bilateral atypical hypertrophic pulmonary osteoarthropathy in the cortex of the femurs.", "width": 1368, "height": 1016, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "b": [64, 65, 66, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63], "c": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 84, 85, 86, 87, 88, 89, 90, 91], "d": [67, 68, 69, 70, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91], "e": [92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113]}, "subfigures": [{"id": "10b8a06b-9527-4dad-b4ef-3686c767bd8d", "label": "a", "points": [[16.2, 6.5], [16.2, 317.7], [446.3, 317.7], [446.3, 6.5]], "color": "yellow"}, {"id": "c3cda43f-1d3e-4e15-8487-488fbaf9825f", "label": "b", "points": [[461.4, 2.2], [461.4, 326.3], [900.1, 326.3], [900.1, 2.2]], "color": "cyan"}, {"id": 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{"pdf_hash": "b8d6dcc6139f6389b773cce2ac242b9826a66a26", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Fig. 2. Two representative cases illustrating the dorsal pancreatic duct (DPD) bypass. a \u2013 d A 47- year-old woman had experienced numerous pain flares of chronic pancreatitis. a The ventral pancreatic duct contains several complex stones in the head of the pancreas. b A high grade 2-mm stenosis immediately upstream from the stones is seen in the ventral pancreatic duct and cannot be crossed with a highly tapered catheter. c The DPD take-off is upstream from the large stone, and deep cannulation of the DPD is accomplished. d After dorsal pancreatic sphincterotomy and dilation with a 4-mm balloon dilator, a 5-Fr pancreatic stent is successfully placed into the DPD. e \u2013 h A 70-year-old man had established chronic recurrent pancreatitis. e A conglomeration of large stones is noted fluoroscopically in the head of the pancreas. Cannulation and visualization of the ventral pancreatic duct failed. f Pancreatography via DPD cannulation shows multiple large obstructing stones in the ventral pancreatic duct in the head of the pancreas. 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{"pdf_hash": "1eb45aad65c0728429792dfdc21a3418e9f1b396", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1. a CT revealed the appendix to be prominently enlarged. The appendix had become enlarged to 25 mm and the appendix walls exhibited hypertrophy (arrow). b, c The results of FDG-PET coincided with a tumor-like shadow observed in CT and abnormal accumulation of FDG was observed. 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{"pdf_hash": "77f5b2af6b61d89bef42cad463236de428b96b0c", "fig_key": "Figure5", "fig_uri": "9-Figure5-1.png", "text": "Fig. 5 Expression of SGLT1 and SGLT2 in glioblastoma cells. A representative sample of human glioblastoma (WHO Grade IV) involving the left frontal lobe, typically characterized by high cellularity, was stained SGLT1, showing mostly nuclear signal (a); SGLT2, showing both nuclear and cytoplasmic staining in tumor cells (c). SGLT1 + antigenic peptide (b); and SGLT2 + antigenic peptide (d). A higher magnification image showing SGLT2 in or close to the plasma membrane (e, red arrowheads), and block by the antigenic peptide (f)", "width": 1182, "height": 1552, "subcaptions": {"a": [37, 38, 39, 40, 41, 42, 43, 44, 45], "b": [62, 63, 64, 65, 66, 67, 68], "c": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "d": [71, 72, 73, 74, 75, 76, 77], "e": [80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97], "f": [100, 101, 102, 103, 104, 105, 106, 107]}, "subfigures": [{"id": "815eae04-8bc0-460c-995a-8dca313c234e", "label": "a", "points": [[5.9, 8.1], [5.9, 517.9], [584.8, 517.9], [584.8, 8.1]], "color": "yellow"}, {"id": "e22d0717-79ff-4062-b511-0c0842dbba3d", "label": "b", "points": [[597.8, 8.1], [597.8, 519.7], [1174.8, 519.7], [1174.8, 8.1]], "color": "cyan"}, {"id": "e5176da2-eca4-4d1f-897b-c263a517a18f", "label": "c", "points": [[5.9, 524.7], [5.9, 1028.9], [588.5, 1028.9], [588.5, 524.7]], "color": "magenta"}, {"id": 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{"pdf_hash": "4405542cadb71c6eba97d2b2a0805ce91e4d3c6b", "fig_key": "Figure7", "fig_uri": "6-Figure7-1.png", "text": "Figure 7. Rotation in spherical P0. Spherical Po embryos were obtained by proteotytic digestion of the ellipsoid eggshell. The white arrows mark the position of the polar body, which defines the anterior pole (Albertson, 1984). The black arrows mark the position of the centrosomes. (Panel 1 ) The centrosomes are lying in a transverse orientation. (Panel 2) After 2 min, the centrosomes have rotated onto the longitudinal axis. In panel 2 the embryo has become elongated presumably by the establishment of the mitotic spindle. 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{"pdf_hash": "ea6688f066c80a9e50cd2a123bc6517fc78b2c08", "fig_key": "Figure22", "fig_uri": "20-Figure22-1.png", "text": "Fig. 22 Imaging tumor using 44 in the tumor-bearing mouse xenograft models prepared by subcutaneous inoculation of HeLa cells. (A) The mouse was subcutaneously injected with 44 (2 mM, 10 mL) in the tumor region and normal region, respectively, and then imaged immediately. (B) Themouse was intravenously injected with 44 (1.5 mg kg 1), and then imaged after 25min. Adapted with permission from ref. 89. 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{"pdf_hash": "df6c8fa0f1d9037b1ac48579a2f82b05c08cd8ee", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 No pulmonary vein stenosis was observed on contrast-enhanced computed tomography (A, B; preablation). Five-and-a-half months after ablation, severe stenosis of the left superior pulmonary vein and complete occlusion of the pulmonary vein for the lingular segment were observed (C, D).", "width": 1046, "height": 936, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "6de9516d-1b9e-4826-9ded-6cb0e4c1ae91", "label": "a", "points": [[26.4, 0], [26.4, 452.8], [563.5, 452.8], [563.5, 0]], "color": "yellow"}, {"id": "20ed40ea-a0cf-492e-8244-5beb7dfe8354", "label": "a", "points": [[28.1, 457.7], [28.1, 903.9], [568.5, 903.9], [568.5, 457.7]], "color": "cyan"}, {"id": "ff581195-02ce-4c45-81a0-e10b023a51ef", "label": "b", "points": [[570.1, 5], [570.1, 454.4], [1017.9, 454.4], [1017.9, 5]], "color": "magenta"}, {"id": "bf18315d-7b70-421a-8ce0-bcab5d83bd15", "label": "b", "points": [[1019.6, 462.7], [1019.6, 902.3], [566.8, 902.3], [566.8, 462.7]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "No", "start": 9, "end": 11, "id": 2}, {"text": "pulmonary", "start": 12, "end": 21, "id": 3}, {"text": "vein", "start": 22, "end": 26, "id": 4}, {"text": "stenosis", "start": 27, "end": 35, "id": 5}, {"text": "was", "start": 36, "end": 39, "id": 6}, {"text": "observed", "start": 40, "end": 48, "id": 7}, {"text": "on", "start": 49, "end": 51, "id": 8}, {"text": "contrast", "start": 52, "end": 60, "id": 9}, {"text": "-", "start": 60, "end": 61, "id": 10}, {"text": "enhanced", "start": 61, "end": 69, "id": 11}, {"text": "computed", "start": 70, "end": 78, "id": 12}, {"text": "tomography", "start": 79, "end": 89, "id": 13}, {"text": "(", "start": 90, "end": 91, "id": 14}, {"text": "A", "start": 91, "end": 92, "id": 15}, {"text": ",", "start": 92, "end": 93, "id": 16}, {"text": "B", "start": 94, "end": 95, "id": 17}, {"text": ";", "start": 95, "end": 96, "id": 18}, {"text": "preablation", "start": 97, "end": 108, "id": 19}, {"text": ")", "start": 108, "end": 109, "id": 20}, {"text": ".", "start": 109, "end": 110, "id": 21}, {"text": "Five", "start": 111, "end": 115, "id": 22}, {"text": "-", "start": 115, "end": 116, "id": 23}, {"text": "and", "start": 116, "end": 119, "id": 24}, {"text": "-", "start": 119, "end": 120, "id": 25}, {"text": "a", "start": 120, "end": 121, "id": 26}, {"text": "-", "start": 121, "end": 122, "id": 27}, {"text": "half", "start": 122, "end": 126, "id": 28}, {"text": "months", "start": 127, "end": 133, "id": 29}, {"text": "after", "start": 134, "end": 139, "id": 30}, {"text": "ablation", "start": 140, "end": 148, "id": 31}, {"text": ",", "start": 148, "end": 149, "id": 32}, {"text": "severe", "start": 150, "end": 156, "id": 33}, {"text": "stenosis", "start": 157, "end": 165, "id": 34}, {"text": "of", "start": 166, "end": 168, "id": 35}, {"text": "the", "start": 169, "end": 172, "id": 36}, {"text": "left", "start": 173, "end": 177, "id": 37}, {"text": "superior", "start": 178, "end": 186, "id": 38}, {"text": "pulmonary", "start": 187, "end": 196, "id": 39}, {"text": "vein", "start": 197, "end": 201, "id": 40}, {"text": "and", "start": 202, "end": 205, "id": 41}, {"text": "complete", "start": 206, "end": 214, "id": 42}, {"text": "occlusion", "start": 215, "end": 224, "id": 43}, {"text": "of", "start": 225, "end": 227, "id": 44}, {"text": "the", "start": 228, "end": 231, "id": 45}, {"text": "pulmonary", "start": 232, "end": 241, "id": 46}, {"text": "vein", "start": 242, "end": 246, "id": 47}, {"text": "for", "start": 247, "end": 250, "id": 48}, {"text": "the", "start": 251, "end": 254, "id": 49}, {"text": "lingular", "start": 255, "end": 263, "id": 50}, {"text": "segment", "start": 264, "end": 271, "id": 51}, {"text": "were", "start": 272, "end": 276, "id": 52}, {"text": "observed", "start": 277, "end": 285, "id": 53}, {"text": "(", "start": 286, "end": 287, "id": 54}, {"text": "C", "start": 287, "end": 288, "id": 55}, {"text": ",", "start": 288, "end": 289, "id": 56}, {"text": "D", "start": 290, "end": 291, "id": 57}, {"text": ")", "start": 291, "end": 292, "id": 58}, {"text": ".", "start": 292, "end": 293, "id": 59}]}
{"pdf_hash": "b3cc2c3f4d1784369b29bdcde33a0b582d5f3b15", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. a-e. CT and MRI images of a patient with AM (a-c) and a patient with AMc (d, e). A normal-size mastoid cavity filled with inflammatory secretions and soft tissue is seen in the CT of a patient with AM (a). MRI gives a better overview of the soft tissue component, showing an intense enhancement of the intramastoid-inflamed mucosa or granulation tissue (b), as well as a necrotic unenhanced area at the tip of the mastoid process (asterisk in c) and periosteal enhancement compatible with periostitis (arrowheads in c). In an AMc patient, a sclerotic mastoid cavity is seen in CT with osteolysis and a bony cortical defect at the tip of the mastoid (arrow in d). 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{"pdf_hash": "9aa257340ccd1266e2e5780e9bc1ba132d565b07", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4 Midsagittal T1-weighted (A) and T2-weighted (B) magnetic resonance (MR) images of an L1\u2013L2 motion segment with poor end plate signal. (C) Corresponding ultrashort time-to-echo (UTE) MR image showing enhanced end plate signal. Arrows indicate end plate defects shown in \u25baFig. 5A and 5B. (UTE imaging courtesy of Drs. 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{"pdf_hash": "5c33f6e358dc0781c2461df1fd29c2f506ef642b", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. A sublingual mass in a 60-year-old man was misdiagnosed as neurilemmoma by pre-(A) and post-contrast (B) CT (arrows). It was diagnosed as ectopic thyroid by scintigraphy (C) and SPECT/CT with 99m TcO 4 \u00c0 (D) (arrow). Histological examination revealed that the mass was nodular goiter that originated from ectopic thyroid. 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{"pdf_hash": "9477f81e3b5c7827ee50cf22ec8531d546aa6ba5", "fig_key": "Figure5", "fig_uri": "9-Figure5-1.png", "text": "Fig 5. CT and MRI morphologic assessment of lung injury. Central coronal images of A first and B second CT scan as well as D first and E third MRI scan showing infiltrates after aspiration in the right lower lobe. Morphologic scoring of lung alterations based on C CT scans and F MRI scans. 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{"pdf_hash": "ef18bb56d5aa389c68582bd1359751aa43d8d09b", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig 3. Long term imaging of mTurq2:Geph puncta. A) A rat cortical neuron expressing mTurq2:Geph within a network of cortical neurons growing on a thin-glass MEA dish (starting at 18 days in vitro). Bar, 20\u03bcm. B) Time-lapse imaging of the region enclosed in rectangle in (A). Images were collected at one hour intervals for 161 hours (~7 days). Only a subset of the data is shown here. Bar: 20\u03bcm. C) High temporal and spatial resolution images of region enclosed in rectangle in (B). Note the excellent ability to follow the same synapses over time. Fluorescence measurement data for the three synapses enclosed in colored rectangles is provided in Fig 5A. The bottom panel demonstrates the programmatic detection of mTurq2:Geph puncta, used thereafter for counting and fluorescence quantification. 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{"pdf_hash": "2d13b82d265658ce792a4ef39f21d5841a9b2969", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4. A 81 year\u2011old female with lumbar pain combined with left lower limb pain for 6 months. The patient had a history of several surgeries for lumbar compression fractures. The underlying diseases included hypertension, diabetes and cerebrovascular disease. The preoperative CCI, VAS and JOA scores were 3, 7 and 12, respectively. VAS and JOA scores 12 months after surgery were 2 and 20, respectively. (A) There was no nerve compression in preoperative imaging examination. The arrow is pointing to L3\u20114 disc herniation. (B) Nerve root angiography showed L3\u20114 disc herniation, stenosis of left nerve root canal and intervertebral foramen. 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{"pdf_hash": "b1635bf8583b7cd43745d5b1e48fc03ccfe549a9", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. (A) Axial T2-weighted image demonstrates the well-circumscribed lesions along the course of the tibial nerve. (B) Distal lesions are well-circumscribed and extend into the soleus muscle.", "width": 1010, "height": 544, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39]}, "subfigures": [{"id": "66f04ce4-4ee6-4b00-8bc9-c52be093d893", "label": "a", "points": [[3.2, 1.6], [3.2, 540.9], [493, 540.9], [493, 1.6]], "color": "yellow"}, {"id": "8967d333-aa0f-4ea1-aa96-e408727c7644", "label": "b", "points": [[502.6, 542.5], [502.6, 4.8], [974.9, 4.8], [974.9, 542.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Axial", "start": 12, "end": 17, "id": 7}, {"text": "T2-weighted", "start": 18, "end": 29, "id": 8}, {"text": "image", "start": 30, "end": 35, "id": 9}, {"text": "demonstrates", "start": 36, "end": 48, "id": 10}, {"text": "the", "start": 49, "end": 52, "id": 11}, {"text": "well", "start": 53, "end": 57, "id": 12}, {"text": "-", "start": 57, "end": 58, "id": 13}, {"text": "circumscribed", "start": 58, "end": 71, "id": 14}, {"text": "lesions", "start": 72, "end": 79, "id": 15}, {"text": "along", "start": 80, "end": 85, "id": 16}, {"text": "the", "start": 86, "end": 89, "id": 17}, {"text": "course", "start": 90, "end": 96, "id": 18}, {"text": "of", "start": 97, "end": 99, "id": 19}, {"text": "the", "start": 100, "end": 103, "id": 20}, {"text": "tibial", "start": 104, "end": 110, "id": 21}, {"text": "nerve", "start": 111, "end": 116, "id": 22}, {"text": ".", "start": 116, "end": 117, "id": 23}, {"text": "(", "start": 118, "end": 119, "id": 24}, {"text": "B", "start": 119, "end": 120, "id": 25}, {"text": ")", "start": 120, "end": 121, "id": 26}, {"text": "Distal", "start": 122, "end": 128, "id": 27}, {"text": "lesions", "start": 129, "end": 136, "id": 28}, {"text": "are", "start": 137, "end": 140, "id": 29}, {"text": "well", "start": 141, "end": 145, "id": 30}, {"text": "-", "start": 145, "end": 146, "id": 31}, {"text": "circumscribed", "start": 146, "end": 159, "id": 32}, {"text": "and", "start": 160, "end": 163, "id": 33}, {"text": "extend", "start": 164, "end": 170, "id": 34}, {"text": "into", "start": 171, "end": 175, "id": 35}, {"text": "the", "start": 176, "end": 179, "id": 36}, {"text": "soleus", "start": 180, "end": 186, "id": 37}, {"text": "muscle", "start": 187, "end": 193, "id": 38}, {"text": ".", "start": 193, "end": 194, "id": 39}]}
{"pdf_hash": "ca9b67aca91ba02cb8f8c84d876ab43e451f78a2", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig 5 \u2013 T1 Post contrast sagittal (left) and axial (right) images showing resolution of tonsillar cerebellar ectopia and greater patency of the subarachnoid spaces (empty arrow). Very mild residual pachymeningeal enhancement (dotted arrow). Decreased sinuses engorgement (curved arrow) and residual occipital sinus (dashed arrows). Findings are improved compared to previous MRI consistent with resolution of intracranial hypotension.", "width": 1000, "height": 552, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [3, 4, 5, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "993e1a18-8381-4223-b9eb-86161ae5e67d", "label": "a", "points": [[11.3, 0.5], [11.3, 550.3], [576.9, 550.3], [576.9, 0.5]], "color": "yellow"}, {"id": "0104c364-12eb-43c3-b611-bfdba6ac55a9", "label": "b", "points": [[589.6, 6.8], [589.6, 547.2], [998.7, 547.2], [998.7, 6.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "5", "start": 4, "end": 5, "id": 1}, {"text": "\u2013", "start": 6, "end": 7, "id": 2}, {"text": "T1", "start": 8, "end": 10, "id": 3}, {"text": "Post", "start": 11, "end": 15, "id": 4}, {"text": "contrast", "start": 16, "end": 24, "id": 5}, {"text": "sagittal", "start": 25, "end": 33, "id": 6}, {"text": "(", "start": 34, "end": 35, "id": 7}, {"text": "left", "start": 35, "end": 39, "id": 8}, {"text": ")", "start": 39, "end": 40, "id": 9}, {"text": "and", "start": 41, "end": 44, "id": 10}, {"text": "axial", "start": 45, "end": 50, "id": 11}, {"text": "(", "start": 51, "end": 52, "id": 12}, {"text": "right", "start": 52, "end": 57, "id": 13}, {"text": ")", "start": 57, "end": 58, "id": 14}, {"text": "images", "start": 59, "end": 65, "id": 15}, {"text": "showing", "start": 66, "end": 73, "id": 16}, {"text": "resolution", "start": 74, "end": 84, "id": 17}, {"text": "of", "start": 85, "end": 87, "id": 18}, {"text": "tonsillar", "start": 88, "end": 97, "id": 19}, {"text": "cerebellar", "start": 98, "end": 108, "id": 20}, {"text": "ectopia", "start": 109, "end": 116, "id": 21}, {"text": "and", "start": 117, "end": 120, "id": 22}, {"text": "greater", "start": 121, "end": 128, "id": 23}, {"text": "patency", "start": 129, "end": 136, "id": 24}, {"text": "of", "start": 137, "end": 139, "id": 25}, {"text": "the", "start": 140, "end": 143, "id": 26}, {"text": "subarachnoid", "start": 144, "end": 156, "id": 27}, {"text": "spaces", "start": 157, "end": 163, "id": 28}, {"text": "(", "start": 164, "end": 165, "id": 29}, {"text": "empty", "start": 165, "end": 170, "id": 30}, {"text": "arrow", "start": 171, "end": 176, "id": 31}, {"text": ")", "start": 176, "end": 177, "id": 32}, {"text": ".", "start": 177, "end": 178, "id": 33}, {"text": "Very", "start": 179, "end": 183, "id": 34}, {"text": "mild", "start": 184, "end": 188, "id": 35}, {"text": "residual", "start": 189, "end": 197, "id": 36}, {"text": "pachymeningeal", "start": 198, "end": 212, "id": 37}, {"text": "enhancement", "start": 213, "end": 224, "id": 38}, {"text": "(", "start": 225, "end": 226, "id": 39}, {"text": "dotted", "start": 226, "end": 232, "id": 40}, {"text": "arrow", "start": 233, "end": 238, "id": 41}, {"text": ")", "start": 238, "end": 239, "id": 42}, {"text": ".", "start": 239, "end": 240, "id": 43}, {"text": "Decreased", "start": 241, "end": 250, "id": 44}, {"text": "sinuses", "start": 251, "end": 258, "id": 45}, {"text": "engorgement", "start": 259, "end": 270, "id": 46}, {"text": "(", "start": 271, "end": 272, "id": 47}, {"text": "curved", "start": 272, "end": 278, "id": 48}, {"text": "arrow", "start": 279, "end": 284, "id": 49}, {"text": ")", "start": 284, "end": 285, "id": 50}, {"text": "and", "start": 286, "end": 289, "id": 51}, {"text": "residual", "start": 290, "end": 298, "id": 52}, {"text": "occipital", "start": 299, "end": 308, "id": 53}, {"text": "sinus", "start": 309, "end": 314, "id": 54}, {"text": "(", "start": 315, "end": 316, "id": 55}, {"text": "dashed", "start": 316, "end": 322, "id": 56}, {"text": "arrows", "start": 323, "end": 329, "id": 57}, {"text": ")", "start": 329, "end": 330, "id": 58}, {"text": ".", "start": 330, "end": 331, "id": 59}, {"text": "Findings", "start": 332, "end": 340, "id": 60}, {"text": "are", "start": 341, "end": 344, "id": 61}, {"text": "improved", "start": 345, "end": 353, "id": 62}, {"text": "compared", "start": 354, "end": 362, "id": 63}, {"text": "to", "start": 363, "end": 365, "id": 64}, {"text": "previous", "start": 366, "end": 374, "id": 65}, {"text": "MRI", "start": 375, "end": 378, "id": 66}, {"text": "consistent", "start": 379, "end": 389, "id": 67}, {"text": "with", "start": 390, "end": 394, "id": 68}, {"text": "resolution", "start": 395, "end": 405, "id": 69}, {"text": "of", "start": 406, "end": 408, "id": 70}, {"text": "intracranial", "start": 409, "end": 421, "id": 71}, {"text": "hypotension", "start": 422, "end": 433, "id": 72}, {"text": ".", "start": 433, "end": 434, "id": 73}]}
{"pdf_hash": "1b68464613faf915c111b95ae51fd221abfa21ee", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Fig. 6 e MRI coronal T1-w fat sat after gadolinium (A) showing the disappearance of the inflammatory enhancement of CS, meninges and infratemporal fossa, and the reperfusion of the aneurysm (maximum diameter of 9 mm); angiographic sequences time-resolved imaging of contrast kinetics (TRICKS) (B) confirming the aneurysmal blood flow and the persistence of intracranial carotid siphon narrowing (arrow).", "width": 998, "height": 490, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74]}, "subfigures": [{"id": "12c6722e-c1d7-4b98-bf7b-10306cea7b0a", "label": "a", "points": [[4.7, 42.6], [4.7, 436.7], [487.2, 436.7], [487.2, 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{"pdf_hash": "4a93e05663474a4945f36e2af30acc955229de49", "fig_key": "Figure8", "fig_uri": "11-Figure8-1.png", "text": "Figure 8. Sub-area and laminar specificity of the cortical connections. Dark-field photomicrographs under polarized light. Dorsal is at the top and medial on the right. Bar = 1 mm. (A) Labeling in the banks of the presylvian sulcus following a dysgranular insular area injection (case no. 851). The lumen of the sulcus is indicated by a black arrowhead. Clusters of labeled terminals and somata are located in the most lateral zone of the dorsolateral prefrontal sector (single white arrow), and in area 6a\u03b3 (double white arrow). Note the numerous small neurons labeled in layer II of the gustatory area (white arrows in the lower left). (B) Labeling in a matching coronal level from a brain injected in the anterior sylvian area (no. 677). Note the conspicuous column-like clusterings of labeled cells and terminals (arrows) in the medial bank of the sulcus, which corresponds to the dorsolateral prefrontal sector. Comparison with (A) shows that the dysgranular insular and anterior sylvian areas are linked to non-overlapping domains of the dorsolateral prefrontal sector. (C) Labeling in the posterior rhinal sulcus after the injection in no. 851. Labeling is present in the medial bank of the sulcus corresponding to areas the dorsolateral entorhinal cortex and medial part of 35. A black arrowhead indicates the lumen of the sulcus. (D) An equivalent coronal level of the posterior rhinal sulcus in case no. 677. Observe that, in contrast to (C), labeling here involves only the lateral bank and lip of the sulcus (areas 36 and lateral half of 35). 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{"pdf_hash": "4c3b6eb7785d8b1fe41c7f675d021fc8c2c2a91d", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1: (A) Preoperative computer tomography anterior view, showing the type-B aortic interruption with the aneurysm arising from the distal segment of the interruption at the level of the left subclavian artery. Innominate vein causing an artefact effect because of its superimposition on the aneurysm. (B) Preoperative computer tomography posterior view, showing the type-B aortic interruption with the aneurysm arising from the distal segment of the interruption at the level of the left subclavian artery. Left subclavian artery origin is dilated and arises from the aneurysm. (C) Diagrammatic representation of the type-B aortic interruption with aneurysm before surgery. 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{"pdf_hash": "e92fc76f6efc9fb7a84698a540d0ce1fac3263d3", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5. Fluorescence imaging of Hg 2+ in HeLa cells at 37\u00b0C (a) bright field image of 2 + Hg 2+ ions-treated HeLa cells; (b) fluorescence imaging of HeLa cells with compound 2 after 10 min of treatment of 10 \u03bcM Hg 2+ ions; (c) HeLa cells incubated with 2 for 30 min.", "width": 1040, "height": 410, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "c": [58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "11633f4d-a6d3-4ab6-9260-5fd59c8fe2d5", "label": "a", "points": [[37, 32.9], [37, 368], [390.2, 368], [390.2, 32.9]], "color": "yellow"}, {"id": "f139d060-f4d9-46ae-a901-ad9895db77b8", "label": "b", "points": [[395.1, 31.2], [395.1, 363.1], [682.7, 363.1], [682.7, 31.2]], "color": "cyan"}, {"id": "296d97e4-bf70-4f28-b61d-67e3bfe14f74", "label": "c", "points": [[692.5, 29.6], [692.5, 376.2], [1006.3, 376.2], [1006.3, 29.6]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Fluorescence", "start": 10, "end": 22, "id": 3}, {"text": "imaging", "start": 23, "end": 30, "id": 4}, {"text": "of", "start": 31, "end": 33, "id": 5}, {"text": "Hg", "start": 34, "end": 36, "id": 6}, {"text": "2", "start": 37, "end": 38, "id": 7}, {"text": "+", "start": 38, "end": 39, "id": 8}, {"text": "in", "start": 40, "end": 42, "id": 9}, {"text": "HeLa", "start": 43, "end": 47, "id": 10}, {"text": "cells", "start": 48, "end": 53, "id": 11}, {"text": "at", "start": 54, "end": 56, "id": 12}, {"text": "37", "start": 57, "end": 59, "id": 13}, {"text": "\u00b0", "start": 59, "end": 60, "id": 14}, {"text": "C", "start": 60, "end": 61, "id": 15}, {"text": "(", "start": 62, "end": 63, "id": 16}, {"text": "a", "start": 63, "end": 64, "id": 17}, {"text": ")", "start": 64, "end": 65, "id": 18}, {"text": "bright", "start": 66, "end": 72, "id": 19}, {"text": "field", "start": 73, "end": 78, "id": 20}, {"text": "image", "start": 79, "end": 84, "id": 21}, {"text": "of", "start": 85, "end": 87, "id": 22}, {"text": "2", "start": 88, "end": 89, "id": 23}, {"text": "+", "start": 90, "end": 91, "id": 24}, {"text": "Hg", "start": 92, "end": 94, "id": 25}, {"text": "2", "start": 95, "end": 96, "id": 26}, {"text": "+", "start": 96, "end": 97, "id": 27}, {"text": "ions", "start": 98, "end": 102, "id": 28}, {"text": "-", "start": 102, "end": 103, "id": 29}, {"text": "treated", "start": 103, "end": 110, "id": 30}, {"text": "HeLa", "start": 111, "end": 115, "id": 31}, {"text": "cells", "start": 116, "end": 121, "id": 32}, {"text": ";", "start": 121, "end": 122, "id": 33}, {"text": "(", "start": 123, "end": 124, "id": 34}, {"text": "b", "start": 124, "end": 125, "id": 35}, {"text": ")", "start": 125, "end": 126, "id": 36}, {"text": "fluorescence", "start": 127, "end": 139, "id": 37}, {"text": "imaging", "start": 140, "end": 147, "id": 38}, {"text": "of", "start": 148, "end": 150, "id": 39}, {"text": "HeLa", "start": 151, "end": 155, "id": 40}, {"text": "cells", "start": 156, "end": 161, "id": 41}, {"text": "with", "start": 162, "end": 166, "id": 42}, {"text": "compound", "start": 167, "end": 175, "id": 43}, {"text": "2", "start": 176, "end": 177, "id": 44}, {"text": "after", "start": 178, "end": 183, "id": 45}, {"text": "10", "start": 184, "end": 186, "id": 46}, {"text": "min", "start": 187, "end": 190, "id": 47}, {"text": "of", "start": 191, "end": 193, "id": 48}, {"text": "treatment", "start": 194, "end": 203, "id": 49}, {"text": "of", "start": 204, "end": 206, "id": 50}, {"text": "10", "start": 207, "end": 209, "id": 51}, {"text": "\u03bcM", "start": 210, "end": 212, "id": 52}, {"text": "Hg", "start": 213, "end": 215, "id": 53}, {"text": "2", "start": 216, "end": 217, "id": 54}, {"text": "+", "start": 217, "end": 218, "id": 55}, {"text": "ions", "start": 219, "end": 223, "id": 56}, {"text": ";", "start": 223, "end": 224, "id": 57}, {"text": "(", "start": 225, "end": 226, "id": 58}, {"text": "c", "start": 226, "end": 227, "id": 59}, {"text": ")", "start": 227, "end": 228, "id": 60}, {"text": "HeLa", "start": 229, "end": 233, "id": 61}, {"text": "cells", "start": 234, "end": 239, "id": 62}, {"text": "incubated", "start": 240, "end": 249, "id": 63}, {"text": "with", "start": 250, "end": 254, "id": 64}, {"text": "2", "start": 255, "end": 256, "id": 65}, {"text": "for", "start": 257, "end": 260, "id": 66}, {"text": "30", "start": 261, "end": 263, "id": 67}, {"text": "min", "start": 264, "end": 267, "id": 68}, {"text": ".", "start": 267, "end": 268, "id": 69}]}
{"pdf_hash": "9890a9d378391aebd1af4432f883b6197c029f97", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 X-ray appearance of pseudoaneurysm. A: Anteroposterior and lateral radiograph of femoral shaft nonunion 8 mo after interlocking IM nailing; B: An ovoid, soft tissue mass behind the fracture site is visible 1 mo after exchange nailing.", "width": 564, "height": 394, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "e6d17f52-b3f7-44b3-92da-4de0880e441c", "label": "a", "points": [[1.5, 1.8], [1.5, 392.9], [280.5, 392.9], [280.5, 1.8]], "color": "yellow"}, {"id": "5e6d2e32-dc84-4902-bffd-db59a16a2ac4", "label": "b", "points": [[293.5, 1.8], [293.5, 391.9], [560.5, 391.9], [560.5, 1.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "X", "start": 9, "end": 10, "id": 2}, {"text": "-", "start": 10, "end": 11, "id": 3}, {"text": "ray", "start": 11, "end": 14, "id": 4}, {"text": "appearance", "start": 15, "end": 25, "id": 5}, {"text": "of", "start": 26, "end": 28, "id": 6}, {"text": "pseudoaneurysm", "start": 29, "end": 43, "id": 7}, {"text": ".", "start": 43, "end": 44, "id": 8}, {"text": "A", "start": 45, "end": 46, "id": 9}, {"text": ":", "start": 46, "end": 47, "id": 10}, {"text": "Anteroposterior", "start": 48, "end": 63, "id": 11}, {"text": "and", "start": 64, "end": 67, "id": 12}, {"text": "lateral", "start": 68, "end": 75, "id": 13}, {"text": "radiograph", "start": 76, "end": 86, "id": 14}, {"text": "of", "start": 87, "end": 89, "id": 15}, {"text": "femoral", "start": 90, "end": 97, "id": 16}, {"text": "shaft", "start": 98, "end": 103, "id": 17}, {"text": "nonunion", "start": 104, "end": 112, "id": 18}, {"text": "8", "start": 113, "end": 114, "id": 19}, {"text": "mo", "start": 115, "end": 117, "id": 20}, {"text": "after", "start": 118, "end": 123, "id": 21}, {"text": "interlocking", "start": 124, "end": 136, "id": 22}, {"text": "IM", "start": 137, "end": 139, "id": 23}, {"text": "nailing", "start": 140, "end": 147, "id": 24}, {"text": ";", "start": 147, "end": 148, "id": 25}, {"text": "B", "start": 149, "end": 150, "id": 26}, {"text": ":", "start": 150, "end": 151, "id": 27}, {"text": "An", "start": 152, "end": 154, "id": 28}, {"text": "ovoid", "start": 155, "end": 160, "id": 29}, {"text": ",", "start": 160, "end": 161, "id": 30}, {"text": "soft", "start": 162, "end": 166, "id": 31}, {"text": "tissue", "start": 167, "end": 173, "id": 32}, {"text": "mass", "start": 174, "end": 178, "id": 33}, {"text": "behind", "start": 179, "end": 185, "id": 34}, {"text": "the", "start": 186, "end": 189, "id": 35}, {"text": "fracture", "start": 190, "end": 198, "id": 36}, {"text": "site", "start": 199, "end": 203, "id": 37}, {"text": "is", "start": 204, "end": 206, "id": 38}, {"text": "visible", "start": 207, "end": 214, "id": 39}, {"text": "1", "start": 215, "end": 216, "id": 40}, {"text": "mo", "start": 217, "end": 219, "id": 41}, {"text": "after", "start": 220, "end": 225, "id": 42}, {"text": "exchange", "start": 226, "end": 234, "id": 43}, {"text": "nailing", "start": 235, "end": 242, "id": 44}, {"text": ".", "start": 242, "end": 243, "id": 45}]}
{"pdf_hash": "0d4742dea69cdc1b6a7f9f3935ed36be203638c7", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. A 30-year-old man presented with left thoracoabdominal stabbing wound. (a) Axial thoracoabdominal CT examination with contrast administration shows subcutaneous air bubbles and hematoma formation in left-anterior abdominal wall as well as omental herniation through the large defect in diaphragm (arrow). (b) An arterial phase axial CT images passing more inferiorly demonstrates a large laceration and tiny pseudoaneurysm in left lobe of liver (arrow). In both images intraabdominal free fluid formations with a dense character consistent with diffuse hemoperitoneum are noted. 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{"pdf_hash": "154f1245b1e859b75a2dc01d53cd93cedd70057b", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3: Coregistration of FMT fluorescence images with CT anatomical images. (a) (Aortic root and arch and carotid arteries), (b) (proximal part of descending aorta) using Cat B FAST, (c) (aortic root and arch and carotid arteries), (d) (proximal part of descending aorta) using IntegriSense.", "width": 1382, "height": 496, "subcaptions": {"a": [36, 37, 38, 39, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [32, 33, 34, 35, 36, 37, 38, 39, 26, 27, 28, 29, 30, 31], "c": [64, 65, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "d": [64, 65, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "813e4357-b5c4-4a62-9e6e-27a11cb81a6e", "label": "a", "points": [[9.1, 37.8], [9.1, 437.4], [325.7, 437.4], [325.7, 37.8]], "color": "yellow"}, {"id": "fa65ae26-bc6a-4e3f-be24-3ba9e5b1048c", "label": "b", "points": [[351.9, 29.1], [351.9, 422.1], [679.4, 422.1], [679.4, 29.1]], "color": "cyan"}, {"id": "d419ead4-750a-4b11-8642-264c5d7cb072", "label": "c", "points": [[718.7, 66.2], [718.7, 424.3], [1050.6, 424.3], [1050.6, 66.2]], "color": "magenta"}, {"id": "a874add3-282b-4fd7-aaf9-e013c30ab7b8", "label": "d", "points": [[1083.3, 83.7], [1083.3, 428.7], [1369.4, 428.7], [1369.4, 83.7]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Coregistration", "start": 10, "end": 24, "id": 3}, {"text": "of", "start": 25, "end": 27, "id": 4}, {"text": "FMT", "start": 28, "end": 31, "id": 5}, {"text": "fluorescence", "start": 32, "end": 44, "id": 6}, {"text": "images", "start": 45, "end": 51, "id": 7}, {"text": "with", "start": 52, "end": 56, "id": 8}, {"text": "CT", "start": 57, "end": 59, "id": 9}, {"text": "anatomical", "start": 60, "end": 70, "id": 10}, {"text": "images", "start": 71, "end": 77, "id": 11}, {"text": ".", "start": 77, "end": 78, "id": 12}, {"text": "(", "start": 79, "end": 80, "id": 13}, {"text": "a", "start": 80, "end": 81, "id": 14}, {"text": ")", "start": 81, "end": 82, "id": 15}, {"text": "(", "start": 83, "end": 84, "id": 16}, {"text": "Aortic", "start": 84, "end": 90, "id": 17}, {"text": "root", "start": 91, "end": 95, "id": 18}, {"text": "and", "start": 96, "end": 99, "id": 19}, {"text": "arch", "start": 100, "end": 104, "id": 20}, {"text": "and", "start": 105, "end": 108, "id": 21}, {"text": "carotid", "start": 109, "end": 116, "id": 22}, {"text": "arteries", "start": 117, "end": 125, "id": 23}, {"text": ")", "start": 125, "end": 126, "id": 24}, {"text": ",", "start": 126, "end": 127, "id": 25}, {"text": "(", "start": 128, "end": 129, "id": 26}, {"text": "b", "start": 129, "end": 130, "id": 27}, {"text": ")", "start": 130, "end": 131, "id": 28}, {"text": "(", "start": 132, "end": 133, "id": 29}, {"text": "proximal", "start": 133, "end": 141, "id": 30}, {"text": "part", "start": 142, "end": 146, "id": 31}, {"text": "of", "start": 147, "end": 149, "id": 32}, {"text": "descending", "start": 150, "end": 160, "id": 33}, {"text": "aorta", "start": 161, "end": 166, "id": 34}, {"text": ")", "start": 166, "end": 167, "id": 35}, {"text": "using", "start": 168, "end": 173, "id": 36}, {"text": "Cat", "start": 174, "end": 177, "id": 37}, {"text": "B", "start": 178, "end": 179, "id": 38}, {"text": "FAST", "start": 180, "end": 184, "id": 39}, {"text": ",", "start": 184, "end": 185, "id": 40}, {"text": "(", "start": 186, "end": 187, "id": 41}, {"text": "c", "start": 187, "end": 188, "id": 42}, {"text": ")", "start": 188, "end": 189, "id": 43}, {"text": "(", "start": 190, "end": 191, "id": 44}, {"text": "aortic", "start": 191, "end": 197, "id": 45}, {"text": "root", "start": 198, "end": 202, "id": 46}, {"text": "and", "start": 203, "end": 206, "id": 47}, {"text": "arch", "start": 207, "end": 211, "id": 48}, {"text": "and", "start": 212, "end": 215, "id": 49}, {"text": "carotid", "start": 216, "end": 223, "id": 50}, {"text": "arteries", "start": 224, "end": 232, "id": 51}, {"text": ")", "start": 232, "end": 233, "id": 52}, {"text": ",", "start": 233, "end": 234, "id": 53}, {"text": "(", "start": 235, "end": 236, "id": 54}, {"text": "d", "start": 236, "end": 237, "id": 55}, {"text": ")", "start": 237, "end": 238, "id": 56}, {"text": "(", "start": 239, "end": 240, "id": 57}, {"text": "proximal", "start": 240, "end": 248, "id": 58}, {"text": "part", "start": 249, "end": 253, "id": 59}, {"text": "of", "start": 254, "end": 256, "id": 60}, {"text": "descending", "start": 257, "end": 267, "id": 61}, {"text": "aorta", "start": 268, "end": 273, "id": 62}, {"text": ")", "start": 273, "end": 274, "id": 63}, {"text": "using", "start": 275, "end": 280, "id": 64}, {"text": "IntegriSense", "start": 281, "end": 293, "id": 65}, {"text": ".", "start": 293, "end": 294, "id": 66}]}
{"pdf_hash": "64052f36cafdbce63b7b2c0a0c1de1a8ccf38351", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig. 1. White matter regions demonstrating a significant effect of pubertal status on mean diffusivity (MD). (A) A large single cluster of voxels from the mean skeleton was identified which showed a decrease in MD in the late puberty group compared with the early puberty group. 3D images in axial, sagittal and coronal dimensions, showing areas demonstrating a significant effect of puberty on MD (red), superimposed on 3D reconstruction of the mean white m D brain I vention a ard brai", "width": 1068, "height": 788, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93]}, "subfigures": [{"id": "9c41de76-b934-402c-9e79-751aa5f87142", "label": "a", "points": [[7, 6.2], [7, 301.4], [1061.5, 301.4], [1061.5, 6.2]], "color": "yellow"}, {"id": "173a9772-485b-46e5-9550-d1786cb70d6c", "label": "b", "points": [[1064.9, 775.6], [1064.9, 308.2], [8.7, 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{"pdf_hash": "a811db8d718877a7f60042d89d665e86171d293c", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Two-dimensional MR images showed the internal structure of porcine knee menisci. (A) Transverse MR plane showed the radially arranged structure. Spatial resolution, 43 43 84 mm. (B) Sagittal MR plane showed the circumferentially arranged structure. Spatial resolution, 59 59 312 mm. (C, D) Transverse MR planes showed tears and disruption of networks of the meniscal tissue (arrows). 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{"pdf_hash": "e6de3d34f4a63b75d8b5749c00d5a7c14cde8119", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4. Images obtained during percutaneous epidural neuroplasty (A). It was performed especially focused on right L5/S1 foramen. MRI obtained after the third operation (B), showing the same level as Fig. 3C, revealed facetectomy and decompression state at right L5/S1 extraforaminal region.", "width": 868, "height": 336, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57]}, "subfigures": [{"id": "5fc4088a-d380-45b7-9b9f-623c85a11b3b", "label": "a", "points": [[3.4, 2.7], [3.4, 305.8], [431.3, 305.8], [431.3, 2.7]], "color": "yellow"}, {"id": "13f9fc7d-5f13-4234-93de-2d592722347f", "label": "b", "points": [[442.2, 2.7], [442.2, 308.5], [863.2, 308.5], [863.2, 2.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Images", "start": 8, "end": 14, "id": 4}, {"text": "obtained", "start": 15, "end": 23, "id": 5}, {"text": "during", "start": 24, "end": 30, "id": 6}, {"text": "percutaneous", "start": 31, "end": 43, "id": 7}, {"text": "epidural", "start": 44, "end": 52, "id": 8}, {"text": "neuroplasty", "start": 53, "end": 64, "id": 9}, {"text": "(", "start": 65, "end": 66, "id": 10}, {"text": "A", "start": 66, "end": 67, "id": 11}, {"text": ")", "start": 67, "end": 68, "id": 12}, {"text": ".", "start": 68, "end": 69, "id": 13}, {"text": "It", "start": 70, "end": 72, "id": 14}, {"text": "was", "start": 73, "end": 76, "id": 15}, {"text": "performed", "start": 77, "end": 86, "id": 16}, {"text": "especially", "start": 87, "end": 97, "id": 17}, {"text": "focused", "start": 98, "end": 105, "id": 18}, {"text": "on", "start": 106, "end": 108, "id": 19}, {"text": "right", "start": 109, "end": 114, "id": 20}, {"text": "L5", "start": 115, "end": 117, "id": 21}, {"text": "/", "start": 117, "end": 118, "id": 22}, {"text": "S1", "start": 118, "end": 120, "id": 23}, {"text": "foramen", "start": 121, "end": 128, "id": 24}, {"text": ".", "start": 128, "end": 129, "id": 25}, {"text": "MRI", "start": 130, "end": 133, "id": 26}, {"text": "obtained", "start": 134, "end": 142, "id": 27}, {"text": "after", "start": 143, "end": 148, "id": 28}, {"text": "the", "start": 149, "end": 152, "id": 29}, {"text": "third", "start": 153, "end": 158, "id": 30}, {"text": "operation", "start": 159, "end": 168, "id": 31}, {"text": "(", "start": 169, "end": 170, "id": 32}, {"text": "B", "start": 170, "end": 171, "id": 33}, {"text": ")", "start": 171, "end": 172, "id": 34}, {"text": ",", "start": 172, "end": 173, "id": 35}, {"text": "showing", "start": 174, "end": 181, "id": 36}, {"text": "the", "start": 182, "end": 185, "id": 37}, {"text": "same", "start": 186, "end": 190, "id": 38}, {"text": "level", "start": 191, "end": 196, "id": 39}, {"text": "as", "start": 197, "end": 199, "id": 40}, {"text": "Fig", "start": 200, "end": 203, "id": 41}, {"text": ".", "start": 203, "end": 204, "id": 42}, {"text": "3C", "start": 205, "end": 207, "id": 43}, {"text": ",", "start": 207, "end": 208, "id": 44}, {"text": "revealed", "start": 209, "end": 217, "id": 45}, {"text": "facetectomy", "start": 218, "end": 229, "id": 46}, {"text": "and", "start": 230, "end": 233, "id": 47}, {"text": "decompression", "start": 234, "end": 247, "id": 48}, {"text": "state", "start": 248, "end": 253, "id": 49}, {"text": "at", "start": 254, "end": 256, "id": 50}, {"text": "right", "start": 257, "end": 262, "id": 51}, {"text": "L5", "start": 263, "end": 265, "id": 52}, {"text": "/", "start": 265, "end": 266, "id": 53}, {"text": "S1", "start": 266, "end": 268, "id": 54}, {"text": "extraforaminal", "start": 269, "end": 283, "id": 55}, {"text": "region", "start": 284, "end": 290, "id": 56}, {"text": ".", "start": 290, "end": 291, "id": 57}]}
{"pdf_hash": "58fd664ac541421bfe210d05612d3f252734a53f", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "FIGURE 4. A, Chest radiograph showing whiteout of the right lung with central mediastinal position. B, Enhanced chest CT scan demonstrating total consolidation of the right lung.", "width": 946, "height": 394, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "461645f6-aae2-41ce-ab42-d46f4ce3bec9", "label": "a", "points": [[37.8, 7.3], [37.8, 364.4], [456.2, 364.4], [456.2, 7.3]], "color": "yellow"}, {"id": "03bc0916-2560-4682-a2ba-38c1870f83b6", "label": "b", "points": [[472.7, 14.7], [472.7, 355.5], [912, 355.5], [912, 14.7]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "Chest", "start": 13, "end": 18, "id": 5}, {"text": "radiograph", "start": 19, "end": 29, "id": 6}, {"text": "showing", "start": 30, "end": 37, "id": 7}, {"text": "whiteout", "start": 38, "end": 46, "id": 8}, {"text": "of", "start": 47, "end": 49, "id": 9}, {"text": "the", "start": 50, "end": 53, "id": 10}, {"text": "right", "start": 54, "end": 59, "id": 11}, {"text": "lung", "start": 60, "end": 64, "id": 12}, {"text": "with", "start": 65, "end": 69, "id": 13}, {"text": "central", "start": 70, "end": 77, "id": 14}, {"text": "mediastinal", "start": 78, "end": 89, "id": 15}, {"text": "position", "start": 90, "end": 98, "id": 16}, {"text": ".", "start": 98, "end": 99, "id": 17}, {"text": "B", "start": 100, "end": 101, "id": 18}, {"text": ",", "start": 101, "end": 102, "id": 19}, {"text": "Enhanced", "start": 103, "end": 111, "id": 20}, {"text": "chest", "start": 112, "end": 117, "id": 21}, {"text": "CT", "start": 118, "end": 120, "id": 22}, {"text": "scan", "start": 121, "end": 125, "id": 23}, {"text": "demonstrating", "start": 126, "end": 139, "id": 24}, {"text": "total", "start": 140, "end": 145, "id": 25}, {"text": "consolidation", "start": 146, "end": 159, "id": 26}, {"text": "of", "start": 160, "end": 162, "id": 27}, {"text": "the", "start": 163, "end": 166, "id": 28}, {"text": "right", "start": 167, "end": 172, "id": 29}, {"text": "lung", "start": 173, "end": 177, "id": 30}, {"text": ".", "start": 177, "end": 178, "id": 31}]}
{"pdf_hash": "8ab17764da3d1f3f22d38832609e6c9240e26473", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Photomicrographs of coronal brain sections showing a partial SCN lesion in animal B26-V34. Much of the SCN is spared in this animal, although circadian rhythmicity is lost after the lesion (behavior shown in Fig. 4A). A\u2013C, Adjacent low-power sections stained for NP, VIP, and CaBP, respectively. A. Low-power view of a section through the SCN stained for NP (arrows indicate NP cells in the dorsomedial SCN). B. The lateral aspect of the SCN is damaged (asterisks). The arrow points to the region shown in high power in E. C, No immunostained cells could be detected in the SCN, although sparse CaBP cells can be seen in the adjacent hypothalamus (arrow). The box denotes the region that is shown in high power in F. D\u2013F, High-power photomicrographs of sections stained for NP, VIP, and CaBP, respectively. No CaBP cells could be detected in the SCN. 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{"pdf_hash": "4debda6024ea4c7f230beae6dea7d6803dbf4cfe", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4 Highlighting of enhanced HCC in real CT-images. Input images (A-D) with the correspondent output of the algorithm (E-H) in the same column. CT slices were obtained from exams of 4 different patients with HCCs, showing the detected HCCs (highlighted region) in the output images.", "width": 1342, "height": 694, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "5802506b-e537-48ab-9cef-afc8ab122ca7", "label": "a", "points": [[28.7, 23], [28.7, 332.5], [344.6, 332.5], [344.6, 23]], "color": "yellow"}, {"id": "d578ed54-ce6b-4b30-ab6a-f384da65a377", "label": "a", "points": [[359.4, 23], [359.4, 341], [671.1, 341], [671.1, 23]], "color": "cyan"}, {"id": "000efd1c-fc65-4245-acb2-bf75d0280495", "label": "a", "points": [[685.9, 25.1], [685.9, 338.9], [995.4, 338.9], [995.4, 25.1]], "color": "magenta"}, {"id": "021742f3-6516-42ec-8562-c14306b25d4b", "label": "a", "points": [[1010.3, 25.1], [1010.3, 343.1], [1317.7, 343.1], [1317.7, 25.1]], "color": "springgreen"}, {"id": "eb84a68d-dd47-41db-a48f-1d3c34b509d2", "label": "b", "points": [[26.6, 347.3], [26.6, 661.1], [340.4, 661.1], [340.4, 347.3]], "color": "tomato"}, {"id": "f951b8be-8737-4a6d-9acf-bfbd2ad7a5d7", "label": "b", "points": [[357.3, 345.2], [357.3, 661.1], [662.6, 661.1], [662.6, 345.2]], "color": "deepskyblue"}, {"id": "fdbdd660-1e9b-4a2a-bc7a-0913c33037da", "label": "b", "points": [[679.6, 347.3], [679.6, 661.1], [995.4, 661.1], [995.4, 347.3]], "color": "orange"}, {"id": "1d2b27a1-470b-4c5b-ad41-104cdb8c22da", "label": "b", "points": [[1008.2, 351.6], [1008.2, 661.1], [1317.7, 661.1], [1317.7, 351.6]], "color": "hotpink"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "Highlighting", "start": 9, "end": 21, "id": 2}, {"text": "of", "start": 22, "end": 24, "id": 3}, {"text": "enhanced", "start": 25, "end": 33, "id": 4}, {"text": "HCC", "start": 34, "end": 37, "id": 5}, {"text": "in", "start": 38, "end": 40, "id": 6}, {"text": "real", "start": 41, "end": 45, "id": 7}, {"text": "CT", "start": 46, "end": 48, "id": 8}, {"text": "-", "start": 48, "end": 49, "id": 9}, {"text": "images", "start": 49, "end": 55, "id": 10}, {"text": ".", "start": 55, "end": 56, "id": 11}, {"text": "Input", "start": 57, "end": 62, "id": 12}, {"text": "images", "start": 63, "end": 69, "id": 13}, {"text": "(", "start": 70, "end": 71, "id": 14}, {"text": "A", "start": 71, "end": 72, "id": 15}, {"text": "-", "start": 72, "end": 73, "id": 16}, {"text": "D", "start": 73, "end": 74, "id": 17}, {"text": ")", "start": 74, "end": 75, "id": 18}, {"text": "with", "start": 76, "end": 80, "id": 19}, {"text": "the", "start": 81, "end": 84, "id": 20}, {"text": "correspondent", "start": 85, "end": 98, "id": 21}, {"text": "output", "start": 99, "end": 105, "id": 22}, {"text": "of", "start": 106, "end": 108, "id": 23}, {"text": "the", "start": 109, "end": 112, "id": 24}, {"text": "algorithm", "start": 113, "end": 122, "id": 25}, {"text": "(", "start": 123, "end": 124, "id": 26}, {"text": "E", "start": 124, "end": 125, "id": 27}, {"text": "-", "start": 125, "end": 126, "id": 28}, {"text": "H", "start": 126, "end": 127, "id": 29}, {"text": ")", "start": 127, "end": 128, "id": 30}, {"text": "in", "start": 129, "end": 131, "id": 31}, {"text": "the", "start": 132, "end": 135, "id": 32}, {"text": "same", "start": 136, "end": 140, "id": 33}, {"text": "column", "start": 141, "end": 147, "id": 34}, {"text": ".", "start": 147, "end": 148, "id": 35}, {"text": "CT", "start": 149, "end": 151, "id": 36}, {"text": "slices", "start": 152, "end": 158, "id": 37}, {"text": "were", "start": 159, "end": 163, "id": 38}, {"text": "obtained", "start": 164, "end": 172, "id": 39}, {"text": "from", "start": 173, "end": 177, "id": 40}, {"text": "exams", "start": 178, "end": 183, "id": 41}, {"text": "of", "start": 184, "end": 186, "id": 42}, {"text": "4", "start": 187, "end": 188, "id": 43}, {"text": "different", "start": 189, "end": 198, "id": 44}, {"text": "patients", "start": 199, "end": 207, "id": 45}, {"text": "with", "start": 208, "end": 212, "id": 46}, {"text": "HCCs", "start": 213, "end": 217, "id": 47}, {"text": ",", "start": 217, "end": 218, "id": 48}, {"text": "showing", "start": 219, "end": 226, "id": 49}, {"text": "the", "start": 227, "end": 230, "id": 50}, {"text": "detected", "start": 231, "end": 239, "id": 51}, {"text": "HCCs", "start": 240, "end": 244, "id": 52}, {"text": "(", "start": 245, "end": 246, "id": 53}, {"text": "highlighted", "start": 246, "end": 257, "id": 54}, {"text": "region", "start": 258, "end": 264, "id": 55}, {"text": ")", "start": 264, "end": 265, "id": 56}, {"text": "in", "start": 266, "end": 268, "id": 57}, {"text": "the", "start": 269, "end": 272, "id": 58}, {"text": "output", "start": 273, "end": 279, "id": 59}, {"text": "images", "start": 280, "end": 286, "id": 60}, {"text": ".", "start": 286, "end": 287, "id": 61}]}
{"pdf_hash": "ad1e76efb8400af08bf6a68fe1d0232af56cc202", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIGURE 1. The tumor (approximately 40 mm in diameter) was hypovascular on enhanced computed tomography scan (right), indicated low intensity on T1-weighted MRI (center), and high intensity on T2-weighted or diffusion MRI (left). Dynamic study revealed peripheral enhancement on a late phase. The tumor located close to the inferior vena cava. 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{"pdf_hash": "0a9307f46066d555e5b183722b516deac58e2d5f", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. CT scan from patient 7 who had a successful Whipple's resection following PDT. (A) Image from CT before PDT showing tumour abutting the superior mesenteric artery (block arrow). (B) Four weeks after PDT, the repeat CT scan at the same level suggested that there was a clear tissue plane between the artery and the tumour (block arrow), so rendering him suitable for surgery. 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{"pdf_hash": "c809961655f69f1576d7ee64b4a62f72382d65e5", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Radiological findings. a Non-enhanced chest CT of mediastinal condition showed a 35-mm mass in the right pulmonary hilum (arrow). b In enhanced chest CT of mediastinal condition, the tumor was strongly enhanced in the early phase (arrow). c In nonenhanced chest CT of lung field condition, abnormal findings were not found in the lung field. d FDG-PET scan showed accumulation only in the mass (arrow)", "width": 1002, "height": 1066, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "c": [50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69], "d": [70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83]}, "subfigures": [{"id": "f3093484-c116-42cd-bc32-99372efe1a3d", "label": "a", "points": 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{"pdf_hash": "8eb319eec88100d7d9a8f3c93198fccfeac936ff", "fig_key": "Figure7", "fig_uri": "9-Figure7-1.png", "text": "FIGURE 7 Arrow maps and magnetite locations of the two oldest subjects. Not shown here are the magnetite masses, calculated separately, but which we placed in Figure 8. (a) Upper right: Arrowmap of the particles of the 81 y/o subject. Other three images of a: Inverse solution placed onto the MRI of that subject. (b) The same for the 89 y/o subject. The location of magnetite particles is seen to be similar for these older diseasefree men, as well as their total mass, seen in Figure 8 to be about 12 \u03bcg [Color figure can be viewed at wileyonlinelibrary.com]", "width": 1182, "height": 628, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65], "b": [35, 36, 37, 38, 39, 40, 41, 42, 56, 57, 58, 59, 60, 61, 62, 66, 67, 68, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110]}, "subfigures": [{"id": "f974135f-9ed6-4af4-8af6-07ffd79cdf7a", "label": "a", "points": [[2.4, 1.6], [2.4, 623.4], [598.1, 623.4], [598.1, 1.6]], "color": "yellow"}, {"id": "3c8cf4c0-d5ae-462a-8462-71a4606ff8a2", "label": "b", "points": [[603.7, 3.5], [603.7, 612.2], [1180.6, 612.2], [1180.6, 3.5]], "color": "cyan"}], "tokens": [{"text": "FIGURE", 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{"pdf_hash": "66e533cb9bc22e8f9e4d3038463fcba149b3d8a0", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1. Hemodynamic features in the patients with SIP and non-SIP. Xe-CT scan images showing that two stroke paients with MCA stenosis had similar infarction in terms of both location (the basal ganglia) and size (A and E). 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{"pdf_hash": "e9b481f3292dc5be2231c13281de9cf3c66f8fe3", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. Nuclear morphological change after MP [4-(39,39- dimethylallyloxy)-5-methyl-6-methoxyphthalide] treatment. DAPI staining of HeLa cells treated without or with 40 mg/mL MP for 12 and 24 h shows chromatin condensation and nuclear fragmentation. The control was treated with 0.05% DMSO for 24 h.", "width": 474, "height": 1098, "subcaptions": {"a": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "b": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 32, 33, 34, 35, 36, 37, 38, 39], "c": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 31, 32, 33, 34, 35, 36, 37, 38, 39]}, "subfigures": [{"id": "523d6c22-4141-44c8-bc90-b090f616cf10", "label": "a", "points": [[4.6, 6.1], [4.6, 358.1], [470.6, 358.1], [470.6, 6.1]], "color": "yellow"}, {"id": "4b4b7fe1-6150-4f86-bea4-da1b680a440f", "label": "b", "points": [[8.6, 373.3], [8.6, 740.4], [472.6, 740.4], [472.6, 373.3]], "color": "cyan"}, {"id": "4c786b00-6ad6-4e42-8a73-5c6b1737d4e1", "label": "b", "points": [[4.6, 749.9], [4.6, 1090.9], [467.6, 1090.9], [467.6, 749.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Nuclear", "start": 10, "end": 17, "id": 3}, {"text": "morphological", "start": 18, "end": 31, "id": 4}, {"text": "change", "start": 32, "end": 38, "id": 5}, {"text": "after", "start": 39, "end": 44, "id": 6}, {"text": "MP", "start": 45, "end": 47, "id": 7}, {"text": "[", "start": 48, "end": 49, "id": 8}, {"text": "4-(39,39-", "start": 49, "end": 58, "id": 9}, {"text": "dimethylallyloxy)-5-methyl-6-methoxyphthalide", "start": 59, "end": 104, "id": 10}, {"text": "]", "start": 104, "end": 105, "id": 11}, {"text": "treatment", "start": 106, "end": 115, "id": 12}, {"text": ".", "start": 115, "end": 116, "id": 13}, {"text": "DAPI", "start": 117, "end": 121, "id": 14}, {"text": "staining", "start": 122, "end": 130, "id": 15}, {"text": "of", "start": 131, "end": 133, "id": 16}, {"text": "HeLa", "start": 134, "end": 138, "id": 17}, {"text": "cells", "start": 139, "end": 144, "id": 18}, {"text": "treated", "start": 145, "end": 152, "id": 19}, {"text": "without", "start": 153, "end": 160, "id": 20}, {"text": "or", "start": 161, "end": 163, "id": 21}, {"text": "with", "start": 164, "end": 168, "id": 22}, {"text": "40", "start": 169, "end": 171, "id": 23}, {"text": "mg", "start": 172, "end": 174, "id": 24}, {"text": "/", "start": 174, "end": 175, "id": 25}, {"text": "mL", "start": 175, "end": 177, "id": 26}, {"text": "MP", "start": 178, "end": 180, "id": 27}, {"text": "for", "start": 181, "end": 184, "id": 28}, {"text": "12", "start": 185, "end": 187, "id": 29}, {"text": "and", "start": 188, "end": 191, "id": 30}, {"text": "24", "start": 192, "end": 194, "id": 31}, {"text": "h", "start": 195, "end": 196, "id": 32}, {"text": "shows", "start": 197, "end": 202, "id": 33}, {"text": "chromatin", "start": 203, "end": 212, "id": 34}, {"text": "condensation", "start": 213, "end": 225, "id": 35}, {"text": "and", "start": 226, "end": 229, "id": 36}, {"text": "nuclear", "start": 230, "end": 237, "id": 37}, {"text": "fragmentation", "start": 238, "end": 251, "id": 38}, {"text": ".", "start": 251, "end": 252, "id": 39}, {"text": "The", "start": 253, "end": 256, "id": 40}, {"text": "control", "start": 257, "end": 264, "id": 41}, {"text": "was", "start": 265, "end": 268, "id": 42}, {"text": "treated", "start": 269, "end": 276, "id": 43}, {"text": "with", "start": 277, "end": 281, "id": 44}, {"text": "0.05", "start": 282, "end": 286, "id": 45}, {"text": "%", "start": 286, "end": 287, "id": 46}, {"text": "DMSO", "start": 288, "end": 292, "id": 47}, {"text": "for", "start": 293, "end": 296, "id": 48}, {"text": "24", "start": 297, "end": 299, "id": 49}, {"text": "h.", "start": 300, "end": 302, "id": 50}]}
{"pdf_hash": "d0bc9c557325c03ff092ea2ad3275f33b345516c", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Figure 6. Three-dimensional computed tomography angiography images just prior to surgery. (A) An anterior view. (B) A lateral view. The anterior wall of T11 was collapsed and the edge of the anterior wall overlapped with adjacent vertebrae, which made the resection line irregular.", "width": 672, "height": 528, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "a7f4a44c-1583-43e0-9f48-613bccf120d6", "label": "a", "points": [[8.8, 26.4], [8.8, 526.4], [320.9, 526.4], [320.9, 26.4]], "color": "yellow"}, {"id": "496b474e-bf95-4d36-855d-ff7524e454c2", "label": "b", "points": [[332.6, 29.6], [332.6, 520], [671.2, 520], [671.2, 29.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Three", "start": 10, "end": 15, "id": 3}, {"text": "-", "start": 15, "end": 16, "id": 4}, {"text": "dimensional", "start": 16, "end": 27, "id": 5}, {"text": "computed", "start": 28, "end": 36, "id": 6}, {"text": "tomography", "start": 37, "end": 47, "id": 7}, {"text": "angiography", "start": 48, "end": 59, "id": 8}, {"text": "images", "start": 60, "end": 66, "id": 9}, {"text": "just", "start": 67, "end": 71, "id": 10}, {"text": "prior", "start": 72, "end": 77, "id": 11}, {"text": "to", "start": 78, "end": 80, "id": 12}, {"text": "surgery", "start": 81, "end": 88, "id": 13}, {"text": ".", "start": 88, "end": 89, "id": 14}, {"text": "(", "start": 90, "end": 91, "id": 15}, {"text": "A", "start": 91, "end": 92, "id": 16}, {"text": ")", "start": 92, "end": 93, "id": 17}, {"text": "An", "start": 94, "end": 96, "id": 18}, {"text": "anterior", "start": 97, "end": 105, "id": 19}, {"text": "view", "start": 106, "end": 110, "id": 20}, {"text": ".", "start": 110, "end": 111, "id": 21}, {"text": "(", "start": 112, "end": 113, "id": 22}, {"text": "B", "start": 113, "end": 114, "id": 23}, {"text": ")", "start": 114, "end": 115, "id": 24}, {"text": "A", "start": 116, "end": 117, "id": 25}, {"text": "lateral", "start": 118, "end": 125, "id": 26}, {"text": "view", "start": 126, "end": 130, "id": 27}, {"text": ".", "start": 130, "end": 131, "id": 28}, {"text": "The", "start": 132, "end": 135, "id": 29}, {"text": "anterior", "start": 136, "end": 144, "id": 30}, {"text": "wall", "start": 145, "end": 149, "id": 31}, {"text": "of", "start": 150, "end": 152, "id": 32}, {"text": "T11", "start": 153, "end": 156, "id": 33}, {"text": "was", "start": 157, "end": 160, "id": 34}, {"text": "collapsed", "start": 161, "end": 170, "id": 35}, {"text": "and", "start": 171, "end": 174, "id": 36}, {"text": "the", "start": 175, "end": 178, "id": 37}, {"text": "edge", "start": 179, "end": 183, "id": 38}, {"text": "of", "start": 184, "end": 186, "id": 39}, {"text": "the", "start": 187, "end": 190, "id": 40}, {"text": "anterior", "start": 191, "end": 199, "id": 41}, {"text": "wall", "start": 200, "end": 204, "id": 42}, {"text": "overlapped", "start": 205, "end": 215, "id": 43}, {"text": "with", "start": 216, "end": 220, "id": 44}, {"text": "adjacent", "start": 221, "end": 229, "id": 45}, {"text": "vertebrae", "start": 230, "end": 239, "id": 46}, {"text": ",", "start": 239, "end": 240, "id": 47}, {"text": "which", "start": 241, "end": 246, "id": 48}, {"text": "made", "start": 247, "end": 251, "id": 49}, {"text": "the", "start": 252, "end": 255, "id": 50}, {"text": "resection", "start": 256, "end": 265, "id": 51}, {"text": "line", "start": 266, "end": 270, "id": 52}, {"text": "irregular", "start": 271, "end": 280, "id": 53}, {"text": ".", "start": 280, "end": 281, "id": 54}]}
{"pdf_hash": "18ac3d0946f3bcf418e67377e4d1b415e26de798", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "FIGURE 2 | Spatial profiles of functional near infrared spectroscopy (fNIRS) channels. The upper panel (A) shows left and right side views of the probe arrangements are shown with fNIRS channel orientation. Detectors are indicated with dark circles, illuminators with light circles, and channels with white squares. Corresponding channel numbers are shown in black. The lower panel (B) shows the estimated channel locations on the brain for both left and right side views. 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{"pdf_hash": "f120ba1a53ad27cc632a2bed4d50b86f4f9493cd", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 PET data (group analysis) showing brain activations following electrotactile stimulation of the tongue following training for the blind (A) and sighted controls (B). Note the rCBF increases in visual cortex of the trained blind only; rCBF changes were correlated with task performance. The left side of the image corresponds to the left side of the brain. 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{"pdf_hash": "31ff24ad96283f8e7710a2413f9b2301dfc30ad0", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 PET and MRI images of a female patient with aortitis (64 years) at the time of diagnosis (A and C) and 3 months later (B and D). (A) and (B) display PET images of a 64 year old patient. Compared with liver tissue, an uptake can be visualised at the ascending aorta, aortic arch, descending (black arrows) and abdominal aorta (A). Three months later there is still an uptake at the ascending aorta aortic arch and descending aorta (arrow). However, comparing the uptake with liver tissue, we see an uptake of equal intensity, interpreted as improvement of the aortic inflammation (B). (C) and (D) show MRI images of the same patient with contrast agent enhancement of the aortic wall (descending aorta) of equal intensity (white arrows) at both times indicating the more \u2018\u2018static\u2019\u2019 results obtained with that imaging technique. 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{"pdf_hash": "636a1ed52756ef3f2acd8db02ae2e6414f263cf9", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Chd7 is expressed in several organs, including organs affected in the CHARGE syndrome. (A\u2013C) Sagittal sections through the head at E12.5 showing Chd7 expression in several areas of the brain, Rathke\u2019s pouch, olfactory epithelium and olfactory ganglion. (D\u2013F) Sagittal sections through the body (E12.5) show Chd7 expression in the lung epithelium, dorsal root ganglia, intestinal epithelium, enteric neurons and blood vessels. (G) A yolk sac (E8.5) stained by whole mount in situ hybridization for Chd7, showing expression in the vascular plexus. (H\u2013I) At E14.5, Chd7 remains expressed strongly in several areas of the brain and the olfactory epithelium. (J) Sense control at E14.5. Scale bar: (A, H and J) 1 mm; (B, D and F) 200 mm; (C and I) 100 mm. 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{"pdf_hash": "5cc0da8465e9692eca28a86e04ed57cb7ad891e9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Computed tomography (CT) scan prior to treatment with imatinib. (B) CT scan after 3 months treatment with imatinib.", "width": 638, "height": 976, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "d5a000f2-dc30-4030-8ffb-d44762452b1d", "label": "a", "points": [[11.6, 1.9], [11.6, 456.4], [633.5, 456.4], [633.5, 1.9]], "color": "yellow"}, {"id": "7c86fe37-57d8-4bf9-b384-4c6dd01bc3a0", "label": "b", "points": [[13.6, 481.1], [13.6, 939.6], [633.5, 939.6], [633.5, 481.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Computed", "start": 14, "end": 22, "id": 6}, {"text": "tomography", "start": 23, "end": 33, "id": 7}, {"text": "(", "start": 34, "end": 35, "id": 8}, {"text": "CT", "start": 35, "end": 37, "id": 9}, {"text": ")", "start": 37, "end": 38, "id": 10}, {"text": "scan", "start": 39, "end": 43, "id": 11}, {"text": "prior", "start": 44, "end": 49, "id": 12}, {"text": "to", "start": 50, "end": 52, "id": 13}, {"text": "treatment", "start": 53, "end": 62, "id": 14}, {"text": "with", "start": 63, "end": 67, "id": 15}, {"text": "imatinib", "start": 68, "end": 76, "id": 16}, {"text": ".", "start": 76, "end": 77, "id": 17}, {"text": "(", "start": 78, "end": 79, "id": 18}, {"text": "B", "start": 79, "end": 80, "id": 19}, {"text": ")", "start": 80, "end": 81, "id": 20}, {"text": "CT", "start": 82, "end": 84, "id": 21}, {"text": "scan", "start": 85, "end": 89, "id": 22}, {"text": "after", "start": 90, "end": 95, "id": 23}, {"text": "3", "start": 96, "end": 97, "id": 24}, {"text": "months", "start": 98, "end": 104, "id": 25}, {"text": "treatment", "start": 105, "end": 114, "id": 26}, {"text": "with", "start": 115, "end": 119, "id": 27}, {"text": "imatinib", "start": 120, "end": 128, "id": 28}, {"text": ".", "start": 128, "end": 129, "id": 29}]}
{"pdf_hash": "0b5b3a92bbba18ad19a09f21e6d4e20d6465ba1e", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 a and b CT guided lung biopsy. Haematoxylin and eosin stain revealed absence of normal alveolar tissue, which were replaced by fibrous tissue. There were areas of histiocytes proliferation with the presence of refractile dental material (blue arrow). The fibrous tissue was lined by ciliated tall columnar respiratory epithelium (black arrow)", "width": 856, "height": 1220, "subcaptions": {"b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "149c80be-2fd9-4b6e-bbf1-1274aac47df9", "label": "a", "points": [[65.1, 27.5], [65.1, 591.4], [815.7, 591.4], [815.7, 27.5]], "color": "yellow"}, {"id": "a0827e5e-4918-456b-ad27-2f632a74446e", "label": "a", "points": [[58.4, 609.9], [58.4, 1177.9], [826.5, 1177.9], [826.5, 609.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "and", "start": 9, "end": 12, "id": 4}, {"text": "b", "start": 13, "end": 14, "id": 5}, {"text": "CT", "start": 15, "end": 17, "id": 6}, {"text": "guided", "start": 18, "end": 24, "id": 7}, {"text": "lung", "start": 25, "end": 29, "id": 8}, {"text": "biopsy", "start": 30, "end": 36, "id": 9}, {"text": ".", "start": 36, "end": 37, "id": 10}, {"text": "Haematoxylin", "start": 38, "end": 50, "id": 11}, {"text": "and", "start": 51, "end": 54, "id": 12}, {"text": "eosin", "start": 55, "end": 60, "id": 13}, {"text": "stain", "start": 61, "end": 66, "id": 14}, {"text": "revealed", "start": 67, "end": 75, "id": 15}, {"text": "absence", "start": 76, "end": 83, "id": 16}, {"text": "of", "start": 84, "end": 86, "id": 17}, {"text": "normal", "start": 87, "end": 93, "id": 18}, {"text": "alveolar", "start": 94, "end": 102, "id": 19}, {"text": "tissue", "start": 103, "end": 109, "id": 20}, {"text": ",", "start": 109, "end": 110, "id": 21}, {"text": "which", "start": 111, "end": 116, "id": 22}, {"text": "were", "start": 117, "end": 121, "id": 23}, {"text": "replaced", "start": 122, "end": 130, "id": 24}, {"text": "by", "start": 131, "end": 133, "id": 25}, {"text": "fibrous", "start": 134, "end": 141, "id": 26}, {"text": "tissue", "start": 142, "end": 148, "id": 27}, {"text": ".", "start": 148, "end": 149, "id": 28}, {"text": "There", "start": 150, "end": 155, "id": 29}, {"text": "were", "start": 156, "end": 160, "id": 30}, {"text": "areas", "start": 161, "end": 166, "id": 31}, {"text": "of", "start": 167, "end": 169, "id": 32}, {"text": "histiocytes", "start": 170, "end": 181, "id": 33}, {"text": "proliferation", "start": 182, "end": 195, "id": 34}, {"text": "with", "start": 196, "end": 200, "id": 35}, {"text": "the", "start": 201, "end": 204, "id": 36}, {"text": "presence", "start": 205, "end": 213, "id": 37}, {"text": "of", "start": 214, "end": 216, "id": 38}, {"text": "refractile", "start": 217, "end": 227, "id": 39}, {"text": "dental", "start": 228, "end": 234, "id": 40}, {"text": "material", "start": 235, "end": 243, "id": 41}, {"text": "(", "start": 244, "end": 245, "id": 42}, {"text": "blue", "start": 245, "end": 249, "id": 43}, {"text": "arrow", "start": 250, "end": 255, "id": 44}, {"text": ")", "start": 255, "end": 256, "id": 45}, {"text": ".", "start": 256, "end": 257, "id": 46}, {"text": "The", "start": 258, "end": 261, "id": 47}, {"text": "fibrous", "start": 262, "end": 269, "id": 48}, {"text": "tissue", "start": 270, "end": 276, "id": 49}, {"text": "was", "start": 277, "end": 280, "id": 50}, {"text": "lined", "start": 281, "end": 286, "id": 51}, {"text": "by", "start": 287, "end": 289, "id": 52}, {"text": "ciliated", "start": 290, "end": 298, "id": 53}, {"text": "tall", "start": 299, "end": 303, "id": 54}, {"text": "columnar", "start": 304, "end": 312, "id": 55}, {"text": "respiratory", "start": 313, "end": 324, "id": 56}, {"text": "epithelium", "start": 325, "end": 335, "id": 57}, {"text": "(", "start": 336, "end": 337, "id": 58}, {"text": "black", "start": 337, "end": 342, "id": 59}, {"text": "arrow", "start": 343, "end": 348, "id": 60}, {"text": ")", "start": 348, "end": 349, "id": 61}]}
{"pdf_hash": "74dcca63ad77214f64b506c3db9b90d9e83935ea", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 | Photographs and CT volume renders of M. minima burrows from the Ediacaran Tamengo Formation, Lad\u00e1rio, Mato Grosso do Sul State, Brazil. a, Representative hand specimen of Tamengo Formation samples, specimen GPIE 11048b. b-d, Oxidized burrows with sub-horizontal trajectories, viewed in plan view on a bedding surface, GPIE-11048b (b), GPIE-11004b (c) and GPIE-11005a (d). Note that these specimens have been heavily weathered. e-g, Volume renders of CT slice data through the burrows constructed using the program Drishti. 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{"pdf_hash": "ed58bce1c0e61b822985efe2e3c693e3852f9c1b", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1. A, Before photodynamic therapy (PDT). Endoscopy shows a protruding mass on the upper esophagus. B, Three days post-PDT. Endoscopy shows coagulation necrosis at the PDT-treated lesion. C, Six weeks post first session of PDT. There was a small residual lesion and the second session of PDT was conducted. 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{"pdf_hash": "20043dcb60c6d0507418019e0586d7ce004055c5", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. \u2013 Evaluation by dual helical lung computed tomography (CT) of pulmonary sarcoid-like granulomas induced by complete Freund9s adjuvant (CFA) in rats. Lung CT from two rats injected with CFA: a) normal lung CT and b) presence of pulmonary nodules. Photomicrographs of lung parenchyma from the same rats stained with haematoxylin and eosin: c) moderate cellular infiltration without granulomas and d) typical sarcoid-like granulomas. The lungs were not inflated prior to fixation, and atelectatic areas are present. 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{"pdf_hash": "c875285cf375cad206539b472bdc053109dd85b7", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. Phenotypes of Lef1 rescued Cdx mutant and Wnt3a mutants, and gene expression in the uro-rectal region. (A-C)\uf020Sagittal sections of the uro-rectal region of a E15.5 control (A), Cdx2/4 rescued by the TPLef1 transgene (B) and Wnt3a hypo/hypo (C). The section in C is not exactly mid-sagittal but shows the bladder-rectum fistula. (D-G)\uf020In situ hybridization of E9.5 whole-mount wild-type embryos with a Cdx2 (D) and Cdx4 (F) probes, and sagittal sections through E9.0 embryos hybridized with the same probes (E and G, respectively). (H,I,L,M) In situ hybridization with an Axin2 probe on a whole-mount E10.5 control (H) and Cdx2/4 embryo (I), and on crosssections (L,M) of these whole mounts at the level indicated by the broken lines in H and I, respectively. (J,K,N,O) In situ hybridization with a Wnt3a probe on a whole-mount E10.5 control (J) and Cdx2/4 mutant (K) embryos, and corresponding transverse sections (N,O). b, bladder; r, rectum; t, tailbud; g, gut; h, hindgut. Asterisk indicates communication between bladder and gut. 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{"pdf_hash": "4e02821b695c2caa6e5d07c48093d475333f7473", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Abdominal and pelvic MRI shows huge lymphangioleiomyomas in the para-aortic area and interior of the pelvis before sirolimus treatment (a). The large lymphangioleiomyomas in the para-aortic area and interior of the pelvis were reduced in size after six months of sirolimus treatment (b).", "width": 656, "height": 454, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "0b7a86f0-3ad7-48dc-b086-02431ed970cf", "label": "a", "points": [[27.5, 0.9], [27.5, 418.5], [341.5, 418.5], [341.5, 0.9]], "color": "yellow"}, {"id": "cb42d56e-5fd8-43f1-9a34-384fe0968ee8", "label": "b", "points": [[355, 1.9], [355, 421.6], [654.5, 421.6], [654.5, 1.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Abdominal", "start": 10, "end": 19, "id": 3}, {"text": "and", "start": 20, "end": 23, "id": 4}, {"text": "pelvic", "start": 24, "end": 30, "id": 5}, {"text": "MRI", "start": 31, "end": 34, "id": 6}, {"text": "shows", "start": 35, "end": 40, "id": 7}, {"text": "huge", "start": 41, "end": 45, "id": 8}, {"text": "lymphangioleiomyomas", "start": 46, "end": 66, "id": 9}, {"text": "in", "start": 67, "end": 69, "id": 10}, {"text": "the", "start": 70, "end": 73, "id": 11}, {"text": "para", "start": 74, "end": 78, "id": 12}, {"text": "-", "start": 78, "end": 79, "id": 13}, {"text": "aortic", "start": 79, "end": 85, "id": 14}, {"text": "area", "start": 86, "end": 90, "id": 15}, {"text": "and", "start": 91, "end": 94, "id": 16}, {"text": "interior", "start": 95, "end": 103, "id": 17}, {"text": "of", "start": 104, "end": 106, "id": 18}, {"text": "the", "start": 107, "end": 110, "id": 19}, {"text": "pelvis", "start": 111, "end": 117, "id": 20}, {"text": "before", "start": 118, "end": 124, "id": 21}, {"text": "sirolimus", "start": 125, "end": 134, "id": 22}, {"text": "treatment", "start": 135, "end": 144, "id": 23}, {"text": "(", "start": 145, "end": 146, "id": 24}, {"text": "a", "start": 146, "end": 147, "id": 25}, {"text": ")", "start": 147, "end": 148, "id": 26}, {"text": ".", "start": 148, "end": 149, "id": 27}, {"text": "The", "start": 150, "end": 153, "id": 28}, {"text": "large", "start": 154, "end": 159, "id": 29}, {"text": "lymphangioleiomyomas", "start": 160, "end": 180, "id": 30}, {"text": "in", "start": 181, "end": 183, "id": 31}, {"text": "the", "start": 184, "end": 187, "id": 32}, {"text": "para", "start": 188, "end": 192, "id": 33}, {"text": "-", "start": 192, "end": 193, "id": 34}, {"text": "aortic", "start": 193, "end": 199, "id": 35}, {"text": "area", "start": 200, "end": 204, "id": 36}, {"text": "and", "start": 205, "end": 208, "id": 37}, {"text": "interior", "start": 209, "end": 217, "id": 38}, {"text": "of", "start": 218, "end": 220, "id": 39}, {"text": "the", "start": 221, "end": 224, "id": 40}, {"text": "pelvis", "start": 225, "end": 231, "id": 41}, {"text": "were", "start": 232, "end": 236, "id": 42}, {"text": "reduced", "start": 237, "end": 244, "id": 43}, {"text": "in", "start": 245, "end": 247, "id": 44}, {"text": "size", "start": 248, "end": 252, "id": 45}, {"text": "after", "start": 253, "end": 258, "id": 46}, {"text": "six", "start": 259, "end": 262, "id": 47}, {"text": "months", "start": 263, "end": 269, "id": 48}, {"text": "of", "start": 270, "end": 272, "id": 49}, {"text": "sirolimus", "start": 273, "end": 282, "id": 50}, {"text": "treatment", "start": 283, "end": 292, "id": 51}, {"text": "(", "start": 293, "end": 294, "id": 52}, {"text": "b", "start": 294, "end": 295, "id": 53}, {"text": ")", "start": 295, "end": 296, "id": 54}, {"text": ".", "start": 296, "end": 297, "id": 55}]}
{"pdf_hash": "244c93e36a5b1ca931d67e69f4ae95008d46680c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Highlights of preoperative images. (A) Coronal contrast-enhanced CT images. CT image showed occupation of the abdominal cavity by a giant tumor enhanced heterogeneously. (B) Coronal 3D-CT angiography. 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{"pdf_hash": "c1775893a037874087a06e3bf233067469aedbc5", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Preoperative sagittal Gd-enhanced T1-weighted MR images demonstrating the tumor on the right prerolandic area. (B) Postoperative sagittal Gd-enhanced T1-weighted MR scans showing the GTR with intracavity BCNU wafer implantation.", "width": 1398, "height": 598, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "34fc4fda-9d74-4d5f-91e9-b708c9364e0c", "label": "a", "points": [[67.4, 8.5], [67.4, 591.5], [665.9, 591.5], [665.9, 8.5]], "color": "yellow"}, {"id": "b19c8396-179f-4c66-9789-e06bf04cdcd3", "label": "b", "points": [[756.5, -0.4], [756.5, 580.5], [1388.1, 580.5], [1388.1, -0.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Preoperative", "start": 14, "end": 26, "id": 6}, {"text": "sagittal", "start": 27, "end": 35, "id": 7}, {"text": "Gd", "start": 36, "end": 38, "id": 8}, {"text": "-", "start": 38, "end": 39, "id": 9}, {"text": "enhanced", "start": 39, "end": 47, "id": 10}, {"text": "T1-weighted", "start": 48, "end": 59, "id": 11}, {"text": "MR", "start": 60, "end": 62, "id": 12}, {"text": "images", "start": 63, "end": 69, "id": 13}, {"text": "demonstrating", "start": 70, "end": 83, "id": 14}, {"text": "the", "start": 84, "end": 87, "id": 15}, {"text": "tumor", "start": 88, "end": 93, "id": 16}, {"text": "on", "start": 94, "end": 96, "id": 17}, {"text": "the", "start": 97, "end": 100, "id": 18}, {"text": "right", "start": 101, "end": 106, "id": 19}, {"text": "prerolandic", "start": 107, "end": 118, "id": 20}, {"text": "area", "start": 119, "end": 123, "id": 21}, {"text": ".", "start": 123, "end": 124, "id": 22}, {"text": "(", "start": 125, "end": 126, "id": 23}, {"text": "B", "start": 126, "end": 127, "id": 24}, {"text": ")", "start": 127, "end": 128, "id": 25}, {"text": "Postoperative", "start": 129, "end": 142, "id": 26}, {"text": "sagittal", "start": 143, "end": 151, "id": 27}, {"text": "Gd", "start": 152, "end": 154, "id": 28}, {"text": "-", "start": 154, "end": 155, "id": 29}, {"text": "enhanced", "start": 155, "end": 163, "id": 30}, {"text": "T1-weighted", "start": 164, "end": 175, "id": 31}, {"text": "MR", "start": 176, "end": 178, "id": 32}, {"text": "scans", "start": 179, "end": 184, "id": 33}, {"text": "showing", "start": 185, "end": 192, "id": 34}, {"text": "the", "start": 193, "end": 196, "id": 35}, {"text": "GTR", "start": 197, "end": 200, "id": 36}, {"text": "with", "start": 201, "end": 205, "id": 37}, {"text": "intracavity", "start": 206, "end": 217, "id": 38}, {"text": "BCNU", "start": 218, "end": 222, "id": 39}, {"text": "wafer", "start": 223, "end": 228, "id": 40}, {"text": "implantation", "start": 229, "end": 241, "id": 41}, {"text": ".", "start": 241, "end": 242, "id": 42}]}
{"pdf_hash": "3b064800d4bfd25ef88ded2252a836d4ae61462f", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3 Lesion overlap for the ACoA controls (n = 7; left) and confabulating patients (n = 4; right) superimposed on a template MRI scan. Colour bars represent the number of patients with lesions that overlap a particular region, with purple being one patient and red being all patients (four in the confabulation group and seven in the ACoA control group). Image was created using MRIcro software (Chris Rorden; www.psychology.nottingham.ac.uk/staff/cr1/mricro.html).", "width": 1176, "height": 944, "subcaptions": {"a": [32, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 26, 27, 28, 29, 30, 31], "b": [32, 3, 4, 5, 6, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "e425914e-5124-4cef-b9bf-16744d574ab6", "label": "a", "points": [[15.9, 1.6], [15.9, 915.6], [589.9, 915.6], [589.9, 1.6]], "color": "yellow"}, {"id": "4c869dba-27c6-4aca-bda0-3a9723073ef5", "label": "b", "points": [[608.5, -0.3], [608.5, 913.7], [1169.5, 913.7], [1169.5, -0.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Lesion", "start": 7, "end": 13, "id": 3}, {"text": "overlap", "start": 14, "end": 21, "id": 4}, {"text": "for", "start": 22, "end": 25, "id": 5}, {"text": "the", "start": 26, "end": 29, "id": 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{"pdf_hash": "40db92a0878afe78cafe41e6ca969283a7c5562b", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Nomarski images of developing vulva. Left lateral views of larval hermaphrodites (anterior to the left). AC, anchor cell. 3, 3\u00b0 VPCs (P4.p and P8.p shown here); 2, 2\u00b0 VPCs (P5.p and P7.p); 1, 1\u00b0 VPC. (A) mid-L3 stage . At this stage, there are no signs of morphological differentiation but P6.p and its daughters express egl-17. B. L3 lethargus. The first two rounds of mitosis of the 2\u00b0 and 1\u00b0 vulval precursors are drawn in, with the axis of the third round of division indicated: L, longitudinal (anterior-posterior); T, transverse (left-right); N, no division; S, fuses with hyp7 epidermal syncytium. In the literature, 1\u00b0 lineages are referred to as [TTTT] or [EFFE]; 2\u00b0 lineages are referred to as [LLTN], [NTLL], [ABCD], or [DCBA]; 3\u00b0 lineages as [S S]; hybrid lineages are [S TN], [NT S], [S TT], [TT S], [LL S] or [S LL]. 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{"pdf_hash": "3026ebee7b350665eadfcfdce72fe9b4e9c26874", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Four chamber view. a. On T2-STIR image, the mass (arrowhead) had similar signal intensity to myocardium revealing a myocardial structure and excluding lipoma. b. On T2-STIR with fat suppression image, the consequence is consistent with (a). c. The cine MRI confirmed a mass (arrow-head) attached to the posterior wall of the right atrium. D. LGE-sequences indicated no abnormal enhancement of the mass (arrow-head). 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{"pdf_hash": "c54120e97e032d68128629cf61f3915f9b6ee723", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1: A one-day-old female with neuroblastoma stage 4s. Sonogram findings: Gray scale sonogram of the liver (performed with a convex transducer, 3.5 MHz) in transverse view (A) shows a diffusely coarse liver (star) and (B) reveals an echogenic nodule (arrow) against the background of diffusely abnormal hepatic echogenicity.", "width": 1150, "height": 440, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67]}, "subfigures": [{"id": "d99caa6a-d65c-44b0-8641-69bca91d6118", "label": "a", "points": [[25.4, 40], [25.4, 405.1], [506.9, 405.1], [506.9, 40]], "color": "yellow"}, {"id": "c054d8ac-ae93-459b-a775-fcf53ab39ace", "label": "b", "points": [[510.5, 405.1], [510.5, 40], [1130, 40], [1130, 405.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "one", "start": 12, "end": 15, "id": 4}, {"text": "-", "start": 15, "end": 16, "id": 5}, {"text": "day", "start": 16, "end": 19, "id": 6}, {"text": "-", "start": 19, "end": 20, "id": 7}, {"text": "old", "start": 20, "end": 23, "id": 8}, {"text": "female", "start": 24, "end": 30, "id": 9}, {"text": "with", "start": 31, "end": 35, "id": 10}, {"text": "neuroblastoma", "start": 36, "end": 49, "id": 11}, {"text": "stage", "start": 50, "end": 55, "id": 12}, {"text": "4s", "start": 56, "end": 58, "id": 13}, {"text": ".", "start": 58, "end": 59, "id": 14}, {"text": "Sonogram", "start": 60, "end": 68, "id": 15}, {"text": "findings", "start": 69, "end": 77, "id": 16}, {"text": ":", "start": 77, "end": 78, "id": 17}, {"text": "Gray", "start": 79, "end": 83, "id": 18}, {"text": "scale", "start": 84, "end": 89, "id": 19}, {"text": "sonogram", "start": 90, "end": 98, "id": 20}, {"text": "of", "start": 99, "end": 101, "id": 21}, {"text": "the", "start": 102, "end": 105, "id": 22}, {"text": "liver", "start": 106, "end": 111, "id": 23}, {"text": "(", "start": 112, "end": 113, "id": 24}, {"text": "performed", "start": 113, "end": 122, "id": 25}, {"text": "with", "start": 123, "end": 127, "id": 26}, {"text": "a", "start": 128, "end": 129, "id": 27}, {"text": "convex", "start": 130, "end": 136, "id": 28}, {"text": "transducer", "start": 137, "end": 147, "id": 29}, {"text": ",", "start": 147, "end": 148, "id": 30}, {"text": "3.5", "start": 149, "end": 152, "id": 31}, {"text": "MHz", "start": 153, "end": 156, "id": 32}, {"text": ")", "start": 156, "end": 157, "id": 33}, {"text": "in", "start": 158, "end": 160, "id": 34}, {"text": "transverse", "start": 161, "end": 171, "id": 35}, {"text": "view", "start": 172, "end": 176, "id": 36}, {"text": "(", "start": 177, "end": 178, "id": 37}, {"text": "A", "start": 178, "end": 179, "id": 38}, {"text": ")", "start": 179, "end": 180, "id": 39}, {"text": "shows", "start": 181, "end": 186, "id": 40}, {"text": "a", "start": 187, "end": 188, "id": 41}, {"text": "diffusely", "start": 189, "end": 198, "id": 42}, {"text": "coarse", "start": 199, "end": 205, "id": 43}, {"text": "liver", "start": 206, "end": 211, "id": 44}, {"text": "(", "start": 212, "end": 213, "id": 45}, {"text": "star", "start": 213, "end": 217, "id": 46}, {"text": ")", "start": 217, "end": 218, "id": 47}, {"text": "and", "start": 219, "end": 222, "id": 48}, {"text": "(", "start": 223, "end": 224, "id": 49}, {"text": "B", "start": 224, "end": 225, "id": 50}, {"text": ")", "start": 225, "end": 226, "id": 51}, {"text": "reveals", "start": 227, "end": 234, "id": 52}, {"text": "an", "start": 235, "end": 237, "id": 53}, {"text": "echogenic", "start": 238, "end": 247, "id": 54}, {"text": "nodule", "start": 248, "end": 254, "id": 55}, {"text": "(", "start": 255, "end": 256, "id": 56}, {"text": "arrow", "start": 256, "end": 261, "id": 57}, {"text": ")", "start": 261, "end": 262, "id": 58}, {"text": "against", "start": 263, "end": 270, "id": 59}, {"text": "the", "start": 271, "end": 274, "id": 60}, {"text": "background", "start": 275, "end": 285, "id": 61}, {"text": "of", "start": 286, "end": 288, "id": 62}, {"text": "diffusely", "start": 289, "end": 298, "id": 63}, {"text": "abnormal", "start": 299, "end": 307, "id": 64}, {"text": "hepatic", "start": 308, "end": 315, "id": 65}, {"text": "echogenicity", "start": 316, "end": 328, "id": 66}, {"text": ".", "start": 328, "end": 329, "id": 67}]}
{"pdf_hash": "7e976a4f64237cc9bcba8c7237017e6c379d25c3", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. A\u2013D. Large-volume and small-volume invaginations. A: 4-cellstage nucleus with a large-volume invagination in contact with a nucleolar precursor body (NPB; the arrow marks the contact site). Note the absence of nuclear pores at the contact site. B: 4-cell-stage nucleus with small-volume invaginations (arrowheads) and multiple large-volume invaginations contacting the same centrally located NPB (arrows mark contact sites between invaginations and the nucleolus). C: 4-cell-stage nucleus with a large-volume invagination reaching across the nucleus to contact a NPB (arrow marks contact site). The arrowhead marks a small-volume invagination emanating from a largevolume invagination. The NPB on the right side is not contacted by any invagination. D: 4-cell-stage nucleus showing three of the four NPBs in contact with large-volume invaginations (contact sites marked by arrows). The NPB not in contact with invaginations is in contact with the nuclear border in another z-section (not shown). E\u2013G: Three types of intranuclear vesicles. E1\u2013G1: Lamin B (3 \u00b5m bar). E2\u2013G2: NUP153. E3\u2013G3 and E4\u2013G4: DAPI (gray), NUP153 (green) and Lamin B (red). E4\u2013G4: Magnification of the vesicles (500 nm bar). E: Lamin B-positive but NUP153-negative intranuclear vesicles are most common. F: Lamin B- and NUP153-positive invaginations are far less common. G: Arrow 2 marks the only occurrence of a NUP153-positive but lamin B-negative vesicle-like structure. 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{"pdf_hash": "f7f245b8d9feaccac92bc58adca68962bf29ace4", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "FIGURE 2 | (A) Tumor lower right lobe on diagnosis (CT scan). (B) Partial response 22 months after start TKI (CT scan). (C) Local progression 26 months after diagnosis (CT scan). (D) Partial response 9 months after local radiotherapy (CT scan).", "width": 686, "height": 632, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "d": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "27bee00f-27b0-4ee7-9f85-2b18ba0599da", "label": "a", "points": [[21.7, 28.2], [21.7, 304.5], [330.5, 304.5], [330.5, 28.2]], "color": "yellow"}, {"id": "57d26900-8272-4894-aeb6-f8beda17dc07", "label": "b", "points": [[663.2, 27.1], [663.2, 306.7], [334.9, 306.7], [334.9, 27.1]], "color": "cyan"}, {"id": "adc8784e-ea62-4bb4-8487-3492b14a3509", "label": "c", "points": [[22.8, 309.9], [22.8, 602.6], [340.3, 602.6], [340.3, 309.9]], "color": "magenta"}, {"id": "43efb964-6f8b-4ba3-b2a2-f7e606a3e803", "label": "d", "points": [[342.5, 603.6], [342.5, 309.9], [664.3, 309.9], [664.3, 603.6]], "color": "springgreen"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "|", "start": 9, "end": 10, "id": 2}, {"text": "(", "start": 11, "end": 12, "id": 3}, {"text": "A", "start": 12, "end": 13, "id": 4}, {"text": ")", "start": 13, "end": 14, "id": 5}, {"text": "Tumor", "start": 15, "end": 20, "id": 6}, {"text": "lower", "start": 21, "end": 26, "id": 7}, {"text": "right", "start": 27, "end": 32, "id": 8}, {"text": "lobe", "start": 33, "end": 37, "id": 9}, {"text": "on", "start": 38, "end": 40, "id": 10}, {"text": "diagnosis", "start": 41, "end": 50, "id": 11}, {"text": "(", "start": 51, "end": 52, "id": 12}, {"text": "CT", "start": 52, "end": 54, "id": 13}, {"text": "scan", "start": 55, "end": 59, "id": 14}, {"text": ")", "start": 59, "end": 60, "id": 15}, {"text": ".", "start": 60, "end": 61, "id": 16}, {"text": "(", "start": 62, "end": 63, "id": 17}, {"text": "B", "start": 63, "end": 64, "id": 18}, {"text": ")", "start": 64, "end": 65, "id": 19}, {"text": "Partial", "start": 66, "end": 73, "id": 20}, {"text": "response", "start": 74, "end": 82, "id": 21}, {"text": "22", "start": 83, "end": 85, "id": 22}, {"text": "months", "start": 86, "end": 92, "id": 23}, {"text": "after", "start": 93, "end": 98, "id": 24}, {"text": "start", "start": 99, "end": 104, "id": 25}, {"text": "TKI", "start": 105, "end": 108, "id": 26}, {"text": "(", "start": 109, "end": 110, "id": 27}, {"text": "CT", "start": 110, "end": 112, "id": 28}, {"text": "scan", "start": 113, "end": 117, "id": 29}, {"text": ")", "start": 117, "end": 118, "id": 30}, {"text": ".", "start": 118, "end": 119, "id": 31}, {"text": "(", "start": 120, "end": 121, "id": 32}, {"text": "C", "start": 121, "end": 122, "id": 33}, {"text": ")", "start": 122, "end": 123, "id": 34}, {"text": "Local", "start": 124, "end": 129, "id": 35}, {"text": "progression", "start": 130, "end": 141, "id": 36}, {"text": "26", "start": 142, "end": 144, "id": 37}, {"text": "months", "start": 145, "end": 151, "id": 38}, {"text": "after", "start": 152, "end": 157, "id": 39}, {"text": "diagnosis", "start": 158, "end": 167, "id": 40}, {"text": "(", "start": 168, "end": 169, "id": 41}, {"text": "CT", "start": 169, "end": 171, "id": 42}, {"text": "scan", "start": 172, "end": 176, "id": 43}, {"text": ")", "start": 176, "end": 177, "id": 44}, {"text": ".", "start": 177, "end": 178, "id": 45}, {"text": "(", "start": 179, "end": 180, "id": 46}, {"text": "D", "start": 180, "end": 181, "id": 47}, {"text": ")", "start": 181, "end": 182, "id": 48}, {"text": "Partial", "start": 183, "end": 190, "id": 49}, {"text": "response", "start": 191, "end": 199, "id": 50}, {"text": "9", "start": 200, "end": 201, "id": 51}, {"text": "months", "start": 202, "end": 208, "id": 52}, {"text": "after", "start": 209, "end": 214, "id": 53}, {"text": "local", "start": 215, "end": 220, "id": 54}, {"text": "radiotherapy", "start": 221, "end": 233, "id": 55}, {"text": "(", "start": 234, "end": 235, "id": 56}, {"text": "CT", "start": 235, "end": 237, "id": 57}, {"text": "scan", "start": 238, "end": 242, "id": 58}, {"text": ")", "start": 242, "end": 243, "id": 59}, {"text": ".", "start": 243, "end": 244, "id": 60}]}
{"pdf_hash": "1fad8cd3cab313eb7110666eda4e863c4d99cfcc", "fig_key": "Figure5", "fig_uri": "8-Figure5-1.png", "text": "Fig. 5. Comparison of preoperative MRI and postimplant CT in two patients. First column: Coregistration of postimplant CT (in color) with preoperative MRI (grayscale); even though registration of the skull, scalp, and right hemisphere is good, many surface electrodes on the coregistered CT land more than 10 mm deep on the MRI in both patients. Second column: Another slice of the CT scan adjusted for contrast to visualize the ventricles. Third column: The corresponding MRI slice. Fourth column: The same MR (color) slice overlaid on the CT (grayscale); note the displacement of the whole brain, including a clear shift of the ventricle and midline, indicating significant brain deformation. 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{"pdf_hash": "222508953c6f75a11a44352d18a676a2248627e3", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 Imaging and Histopatological features of MB2. MRI. Axial T2-weighted image (a) and sagittal T1-weighted image (b) show a nodular mass originating from the vermis and bulging into the fourth ventricle. Apparent diffusion coefficient (ADC) map (c) shows lack of diffusion restriction. Perfusion weighted imaging (d) reveals hyperperfusion within the lesion. (e) Tumor is characterized by pleomorphic cells with large nuclei, prominent nucleoli and moderate eosinophilic cytoplasm. (f) Large cells show immunoreactivity for synaptophysin. (g) N-Myc oncogene amplification (green spots) detected in neoplastic nuclei (blue) and centromere 8 signals (red spots) using CEP8/BAC as FISH probes. Red arrow: N-Myc amplified cell. 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{"pdf_hash": "d0dc476dc658cc8c8c55439d6d319c03420e7c48", "fig_key": "Figure5", "fig_uri": "3-Figure5-1.png", "text": "Figure 5. a\u2013d. Diabetic mastopathy. Axial grey-scale US image (a) shows an irregular, parallel, heterogeneous lesion (arrows). Axial T1-weighted image (b) shows an irregular lesion with irregular margin (arrow). Maximum intensity projection image (c) reveals heterogeneous, regional enhancement (arrow) The lesion demonstrated type II kinetic (not shown). The lesion was categorized as BI-RADS category 4c. Histopathologic examination (d) (H-E, \u00d740) demonstrates perivascular lymphocytic infiltration (arrows) associated with atrophic lobules within areas of stromal fibrosis.", "width": 1418, "height": 246, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "c": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84], "d": [85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113]}, "subfigures": [{"id": "57348c92-0e79-4b55-b280-4f690aa910e1", "label": "a", "points": [[2.9, 4.2], [2.9, 232.7], [332.2, 232.7], [332.2, 4.2]], "color": "yellow"}, {"id": "4a57bd4b-b162-4965-9e23-4c874a95b0d0", "label": "b", "points": [[361.3, 10.9], [361.3, 226], [695.2, 226], [695.2, 10.9]], "color": "cyan"}, {"id": 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{"pdf_hash": "cc873b10fc07b1b5c84ee9479c8e2e8260da6944", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 Normal fetal esophagus at 28 wk of gestation. A and B: 4DUS using HDlive TM application may be used to obtain a clear imaging of inner structure of esophagus (arrow) during fetal swallowing at the time of routine second trimester scan.", "width": 642, "height": 442, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "05f8d3f4-9fcc-4de3-8dd4-91a56cb0b15f", "label": "a", "points": [[-0.5, 7.2], [-0.5, 435.2], [297.7, 435.2], [297.7, 7.2]], "color": "yellow"}, {"id": "8b9e8553-ee02-4593-9050-be2270e5b189", "label": "a", "points": [[312.9, 2.1], [312.9, 438.2], [640.5, 438.2], [640.5, 2.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Normal", "start": 9, "end": 15, "id": 2}, {"text": "fetal", "start": 16, "end": 21, "id": 3}, {"text": "esophagus", "start": 22, "end": 31, "id": 4}, {"text": "at", "start": 32, "end": 34, "id": 5}, {"text": "28", "start": 35, "end": 37, "id": 6}, {"text": "wk", "start": 38, "end": 40, "id": 7}, {"text": "of", "start": 41, "end": 43, "id": 8}, {"text": "gestation", "start": 44, "end": 53, "id": 9}, {"text": ".", "start": 53, "end": 54, "id": 10}, {"text": "A", "start": 55, "end": 56, "id": 11}, {"text": "and", "start": 57, "end": 60, "id": 12}, {"text": "B", "start": 61, "end": 62, "id": 13}, {"text": ":", "start": 62, "end": 63, "id": 14}, {"text": "4DUS", "start": 64, "end": 68, "id": 15}, {"text": "using", "start": 69, "end": 74, "id": 16}, {"text": "HDlive", "start": 75, "end": 81, "id": 17}, {"text": "TM", "start": 82, "end": 84, "id": 18}, {"text": "application", "start": 85, "end": 96, "id": 19}, {"text": "may", "start": 97, "end": 100, "id": 20}, {"text": "be", "start": 101, "end": 103, "id": 21}, {"text": "used", "start": 104, "end": 108, "id": 22}, {"text": "to", "start": 109, "end": 111, "id": 23}, {"text": "obtain", "start": 112, "end": 118, "id": 24}, {"text": "a", "start": 119, "end": 120, "id": 25}, {"text": "clear", "start": 121, "end": 126, "id": 26}, {"text": "imaging", "start": 127, "end": 134, "id": 27}, {"text": "of", "start": 135, "end": 137, "id": 28}, {"text": "inner", "start": 138, "end": 143, "id": 29}, {"text": "structure", "start": 144, "end": 153, "id": 30}, {"text": "of", "start": 154, "end": 156, "id": 31}, {"text": "esophagus", "start": 157, "end": 166, "id": 32}, {"text": "(", "start": 167, "end": 168, "id": 33}, {"text": "arrow", "start": 168, "end": 173, "id": 34}, {"text": ")", "start": 173, "end": 174, "id": 35}, {"text": "during", "start": 175, "end": 181, "id": 36}, {"text": "fetal", "start": 182, "end": 187, "id": 37}, {"text": "swallowing", "start": 188, "end": 198, "id": 38}, {"text": "at", "start": 199, "end": 201, "id": 39}, {"text": "the", "start": 202, "end": 205, "id": 40}, {"text": "time", "start": 206, "end": 210, "id": 41}, {"text": "of", "start": 211, "end": 213, "id": 42}, {"text": "routine", "start": 214, "end": 221, "id": 43}, {"text": "second", "start": 222, "end": 228, "id": 44}, {"text": "trimester", "start": 229, "end": 238, "id": 45}, {"text": "scan", "start": 239, "end": 243, "id": 46}, {"text": ".", "start": 243, "end": 244, "id": 47}]}
{"pdf_hash": "65b490edbf6a3560a09e901b6d8976ac91dbe00c", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. Local tumor recurrence after TACE in 80-year-old female with hepatocellular carcinoma. A. Arterial-phase CT scan showing 1.5 cm-sized hypervascular tumor at segment 8 of right hepatic lobe. Posterior aspect of tumor is relatively hypovascular (black arrows). B. On cone-beam CT hepatic arteriography, anterior hypervascular part of tumor showed strong contrast enhancement with clear tumor margin. In contrast, posterior hypovascular part showed subtle contrast enhancement with indistinct tumor margin (black arrows). C. After subsegmental TACE, tumor showed heterogeneous lipiodol uptake (dense lipiodol uptake in hypervascular component and faint lipiodol uptake in hypovascular component) (white arrow) on lipiodol CT. D. Three years later, arterial-phase CT scan showed enhanced recurrent tumor at area of hypovascular component (black arrowheads). 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{"pdf_hash": "6b794a5fa819b5171073e50a6058ff1708014ba2", "fig_key": "Figure8", "fig_uri": "5-Figure8-1.png", "text": "Fig. 8. Follow-up computed tomography (A) and positron emission tomography (B) images of Case 2 showing metastatic lesions at the pelvis (arrows).", "width": 1338, "height": 674, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [32, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "6591b1fa-a34a-4323-aa9e-d22de47e6cd6", "label": "a", "points": [[9.6, 3.9], [9.6, 640.1], [747.3, 640.1], [747.3, 3.9]], "color": "yellow"}, {"id": "5362082f-a637-4fc7-a74b-a4a66bd0f215", "label": "b", "points": [[764.2, 12.3], [764.2, 638], [1332.8, 638], [1332.8, 12.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "8", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Follow", "start": 8, "end": 14, "id": 4}, {"text": "-", "start": 14, "end": 15, "id": 5}, {"text": "up", "start": 15, "end": 17, "id": 6}, {"text": "computed", "start": 18, "end": 26, "id": 7}, {"text": "tomography", "start": 27, "end": 37, "id": 8}, {"text": "(", "start": 38, "end": 39, "id": 9}, {"text": "A", "start": 39, "end": 40, "id": 10}, {"text": ")", "start": 40, "end": 41, "id": 11}, {"text": "and", "start": 42, "end": 45, "id": 12}, {"text": "positron", "start": 46, "end": 54, "id": 13}, {"text": "emission", "start": 55, "end": 63, "id": 14}, {"text": "tomography", "start": 64, "end": 74, "id": 15}, {"text": "(", "start": 75, "end": 76, "id": 16}, {"text": "B", "start": 76, "end": 77, "id": 17}, {"text": ")", "start": 77, "end": 78, "id": 18}, {"text": "images", "start": 79, "end": 85, "id": 19}, {"text": "of", "start": 86, "end": 88, "id": 20}, {"text": "Case", "start": 89, "end": 93, "id": 21}, {"text": "2", "start": 94, "end": 95, "id": 22}, {"text": "showing", "start": 96, "end": 103, "id": 23}, {"text": "metastatic", "start": 104, "end": 114, "id": 24}, {"text": "lesions", "start": 115, "end": 122, "id": 25}, {"text": "at", "start": 123, "end": 125, "id": 26}, {"text": "the", "start": 126, "end": 129, "id": 27}, {"text": "pelvis", "start": 130, "end": 136, "id": 28}, {"text": "(", "start": 137, "end": 138, "id": 29}, {"text": "arrows", "start": 138, "end": 144, "id": 30}, {"text": ")", "start": 144, "end": 145, "id": 31}, {"text": ".", "start": 145, "end": 146, "id": 32}]}
{"pdf_hash": "a3625944e86d7b9efb7ab8f5b46d2215c91675e3", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "Fig. 7. 24-Year-old female with CD and vulvar-perineal swelling, without appreciable fistulous orifices. 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{"pdf_hash": "7c461f663d07034aef91e609670dda79d467c5d5", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 \u2014 Pituitary adenoma with cystic changes. A) CT scan (following intravenous contrast) showing the tumour extending into the suprasellar region. B) NMR scan, coronal view clearly shows the large tumour.", "width": 1422, "height": 544, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "c": [0]}, "subfigures": [{"id": "1c4d2d53-b638-4b81-b969-92676eee9861", "label": "a", "points": [[2.6, 9.7], [2.6, 450.1], [398, 450.1], [398, 9.7]], "color": "yellow"}, {"id": "6d15f00f-c370-4d6b-9a4d-f60469fa13ab", "label": "b", "points": [[494.6, 3], [494.6, 472.5], [923.7, 472.5], [923.7, 3]], "color": "cyan"}, {"id": "6fedd17b-2861-4a36-84fb-beec86264973", "label": "c", "points": [[1006.8, 9.7], [1006.8, 470.3], [1418, 470.3], [1418, 9.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "\u2014", "start": 9, "end": 10, "id": 2}, {"text": "Pituitary", "start": 11, "end": 20, "id": 3}, {"text": "adenoma", "start": 21, "end": 28, "id": 4}, {"text": "with", "start": 29, "end": 33, "id": 5}, {"text": "cystic", "start": 34, "end": 40, "id": 6}, {"text": "changes", "start": 41, "end": 48, "id": 7}, {"text": ".", "start": 48, "end": 49, "id": 8}, {"text": "A", "start": 50, "end": 51, "id": 9}, {"text": ")", "start": 51, "end": 52, "id": 10}, {"text": "CT", "start": 53, "end": 55, "id": 11}, {"text": "scan", "start": 56, "end": 60, "id": 12}, {"text": "(", "start": 61, "end": 62, "id": 13}, {"text": "following", "start": 62, "end": 71, "id": 14}, {"text": "intravenous", "start": 72, "end": 83, "id": 15}, {"text": "contrast", "start": 84, "end": 92, "id": 16}, {"text": ")", "start": 92, "end": 93, "id": 17}, {"text": "showing", "start": 94, "end": 101, "id": 18}, {"text": "the", "start": 102, "end": 105, "id": 19}, {"text": "tumour", "start": 106, "end": 112, "id": 20}, {"text": "extending", "start": 113, "end": 122, "id": 21}, {"text": "into", "start": 123, "end": 127, "id": 22}, {"text": "the", "start": 128, "end": 131, "id": 23}, {"text": "suprasellar", "start": 132, "end": 143, "id": 24}, {"text": "region", "start": 144, "end": 150, "id": 25}, {"text": ".", "start": 150, "end": 151, "id": 26}, {"text": "B", "start": 152, "end": 153, "id": 27}, {"text": ")", "start": 153, "end": 154, "id": 28}, {"text": "NMR", "start": 155, "end": 158, "id": 29}, {"text": "scan", "start": 159, "end": 163, "id": 30}, {"text": ",", "start": 163, "end": 164, "id": 31}, {"text": "coronal", "start": 165, "end": 172, "id": 32}, {"text": "view", "start": 173, "end": 177, "id": 33}, {"text": "clearly", "start": 178, "end": 185, "id": 34}, {"text": "shows", "start": 186, "end": 191, "id": 35}, {"text": "the", "start": 192, "end": 195, "id": 36}, {"text": "large", "start": 196, "end": 201, "id": 37}, {"text": "tumour", "start": 202, "end": 208, "id": 38}, {"text": ".", "start": 208, "end": 209, "id": 39}]}
{"pdf_hash": "3f139eb5d172b96ccd35564b4678f878f20958cb", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 CT scan of our patient\u2019s chest on admission to our hospital. (A) Chest CT scan shows GGO (arrow) in her left S10 lung segment of 1.3 cm in size. (B) Chest CT scan shows a solitary small nodule (arrow) of 5 mm in diameter in her left S4 segment.", "width": 1342, "height": 762, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "8c3d61c5-7b0f-4110-ac30-a2d2fb8613f4", "label": "a", "points": [[19.4, 17.7], [19.4, 734.3], [655.5, 734.3], [655.5, 17.7]], "color": "yellow"}, {"id": "56d2f026-856d-4d2e-89a2-4a9bee1d0a9a", "label": "b", "points": [[695.7, 21.9], [695.7, 734.3], [1340.3, 734.3], [1340.3, 21.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "CT", "start": 9, "end": 11, "id": 2}, {"text": "scan", "start": 12, "end": 16, "id": 3}, {"text": "of", "start": 17, "end": 19, "id": 4}, {"text": "our", "start": 20, "end": 23, "id": 5}, {"text": "patient", "start": 24, "end": 31, "id": 6}, {"text": "\u2019s", "start": 31, "end": 33, "id": 7}, {"text": "chest", "start": 34, "end": 39, "id": 8}, {"text": "on", "start": 40, "end": 42, "id": 9}, {"text": "admission", "start": 43, "end": 52, "id": 10}, {"text": "to", "start": 53, "end": 55, "id": 11}, {"text": "our", "start": 56, "end": 59, "id": 12}, {"text": "hospital", "start": 60, "end": 68, "id": 13}, {"text": ".", "start": 68, "end": 69, "id": 14}, {"text": "(", "start": 70, "end": 71, "id": 15}, {"text": "A", "start": 71, "end": 72, "id": 16}, {"text": ")", "start": 72, "end": 73, "id": 17}, {"text": "Chest", "start": 74, "end": 79, "id": 18}, {"text": "CT", "start": 80, "end": 82, "id": 19}, {"text": "scan", "start": 83, "end": 87, "id": 20}, {"text": "shows", "start": 88, "end": 93, "id": 21}, {"text": "GGO", "start": 94, "end": 97, "id": 22}, {"text": "(", "start": 98, "end": 99, "id": 23}, {"text": "arrow", "start": 99, "end": 104, "id": 24}, {"text": ")", "start": 104, "end": 105, "id": 25}, {"text": "in", "start": 106, "end": 108, "id": 26}, {"text": "her", "start": 109, "end": 112, "id": 27}, {"text": "left", "start": 113, "end": 117, "id": 28}, {"text": "S10", "start": 118, "end": 121, "id": 29}, {"text": "lung", "start": 122, "end": 126, "id": 30}, {"text": "segment", "start": 127, "end": 134, "id": 31}, {"text": "of", "start": 135, "end": 137, "id": 32}, {"text": "1.3", "start": 138, "end": 141, "id": 33}, {"text": "cm", "start": 142, "end": 144, "id": 34}, {"text": "in", "start": 145, "end": 147, "id": 35}, {"text": "size", "start": 148, "end": 152, "id": 36}, {"text": ".", "start": 152, "end": 153, "id": 37}, {"text": "(", "start": 154, "end": 155, "id": 38}, {"text": "B", "start": 155, "end": 156, "id": 39}, {"text": ")", "start": 156, "end": 157, "id": 40}, {"text": "Chest", "start": 158, "end": 163, "id": 41}, {"text": "CT", "start": 164, "end": 166, "id": 42}, {"text": "scan", "start": 167, "end": 171, "id": 43}, {"text": "shows", "start": 172, "end": 177, "id": 44}, {"text": "a", "start": 178, "end": 179, "id": 45}, {"text": "solitary", "start": 180, "end": 188, "id": 46}, {"text": "small", "start": 189, "end": 194, "id": 47}, {"text": "nodule", "start": 195, "end": 201, "id": 48}, {"text": "(", "start": 202, "end": 203, "id": 49}, {"text": "arrow", "start": 203, "end": 208, "id": 50}, {"text": ")", "start": 208, "end": 209, "id": 51}, {"text": "of", "start": 210, "end": 212, "id": 52}, {"text": "5", "start": 213, "end": 214, "id": 53}, {"text": "mm", "start": 215, "end": 217, "id": 54}, {"text": "in", "start": 218, "end": 220, "id": 55}, {"text": "diameter", "start": 221, "end": 229, "id": 56}, {"text": "in", "start": 230, "end": 232, "id": 57}, {"text": "her", "start": 233, "end": 236, "id": 58}, {"text": "left", "start": 237, "end": 241, "id": 59}, {"text": "S4", "start": 242, "end": 244, "id": 60}, {"text": "segment", "start": 245, "end": 252, "id": 61}, {"text": ".", "start": 252, "end": 253, "id": 62}]}
{"pdf_hash": "f5da532dda8f5c706e29d4c63e57fb95a8c7fd71", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Representative examples of minor-grade (top row) and moderate-grade (bottom row) bleomycin-induced pulmonary changes on pretreatment, restaging, and follow-up computed tomography scans (left to right).", "width": 1206, "height": 584, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12], "b": [13, 14, 15, 16, 17, 18, 19, 20]}, "subfigures": [{"id": "a05faa46-9022-4fe6-8da2-6d1a98a385c3", "label": "a", "points": [[94.6, 59.3], [94.6, 273.3], [419.6, 273.3], [419.6, 59.3]], "color": "yellow"}, {"id": "e56649ea-1c22-4b67-a940-6f3bd2ce6fce", "label": "b", "points": [[444.4, 49.7], [444.4, 282.9], [778.9, 282.9], [778.9, 49.7]], "color": "cyan"}, {"id": "7d9a6498-b892-4c48-b371-806cdcd53a65", "label": "c", "points": [[813.3, 55.4], [813.3, 275.2], [1128.7, 275.2], [1128.7, 55.4]], "color": "magenta"}, {"id": "30173ca5-f7a0-4851-ace8-12c399042d63", "label": "d", "points": [[92.7, 292.4], [92.7, 516.1], [406.2, 516.1], [406.2, 292.4]], "color": "springgreen"}, {"id": "e823670b-61d1-44a1-8c72-f610b30fd284", "label": "e", "points": [[448.2, 292.4], [448.2, 518], [778.9, 518], [778.9, 292.4]], "color": "tomato"}, {"id": "23ef4dcc-1943-499c-a7be-fdb6a54b3229", "label": "f", "points": [[817.1, 284.8], [817.1, 516.1], [1132.5, 516.1], [1132.5, 284.8]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Representative", "start": 10, "end": 24, "id": 3}, {"text": "examples", "start": 25, "end": 33, "id": 4}, {"text": "of", "start": 34, "end": 36, "id": 5}, {"text": "minor", "start": 37, "end": 42, "id": 6}, {"text": "-", "start": 42, "end": 43, "id": 7}, {"text": "grade", "start": 43, "end": 48, "id": 8}, {"text": "(", "start": 49, "end": 50, "id": 9}, {"text": "top", "start": 50, "end": 53, "id": 10}, {"text": "row", "start": 54, "end": 57, "id": 11}, {"text": ")", "start": 57, "end": 58, "id": 12}, {"text": "and", "start": 59, "end": 62, "id": 13}, {"text": "moderate", "start": 63, "end": 71, "id": 14}, {"text": "-", "start": 71, "end": 72, "id": 15}, {"text": "grade", "start": 72, "end": 77, "id": 16}, {"text": "(", "start": 78, "end": 79, "id": 17}, {"text": "bottom", "start": 79, "end": 85, "id": 18}, {"text": "row", "start": 86, "end": 89, "id": 19}, {"text": ")", "start": 89, "end": 90, "id": 20}, {"text": "bleomycin", "start": 91, "end": 100, "id": 21}, {"text": "-", "start": 100, "end": 101, "id": 22}, {"text": "induced", "start": 101, "end": 108, "id": 23}, {"text": "pulmonary", "start": 109, "end": 118, "id": 24}, {"text": "changes", "start": 119, "end": 126, "id": 25}, {"text": "on", "start": 127, "end": 129, "id": 26}, {"text": "pretreatment", "start": 130, "end": 142, "id": 27}, {"text": ",", "start": 142, "end": 143, "id": 28}, {"text": "restaging", "start": 144, "end": 153, "id": 29}, {"text": ",", "start": 153, "end": 154, "id": 30}, {"text": "and", "start": 155, "end": 158, "id": 31}, {"text": "follow", "start": 159, "end": 165, "id": 32}, {"text": "-", "start": 165, "end": 166, "id": 33}, {"text": "up", "start": 166, "end": 168, "id": 34}, {"text": "computed", "start": 169, "end": 177, "id": 35}, {"text": "tomography", "start": 178, "end": 188, "id": 36}, {"text": "scans", "start": 189, "end": 194, "id": 37}, {"text": "(", "start": 195, "end": 196, "id": 38}, {"text": "left", "start": 196, "end": 200, "id": 39}, {"text": "to", "start": 201, "end": 203, "id": 40}, {"text": "right", "start": 204, "end": 209, "id": 41}, {"text": ")", "start": 209, "end": 210, "id": 42}, {"text": ".", "start": 210, "end": 211, "id": 43}]}
{"pdf_hash": "3bf7cf603248936bd5f34064fca083d8417656b0", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Fig. 6. General linear model analysis of task-induced-deactivations (TIDs) in young and older adults across different task loads. Older adults showed smaller extent of TIDs relative to young subjects in both mPFC and posterior midline regions (A). Subjects showed greater deactivations at 2-back in middle dorsal cingulate and BA10 (B). There was a significant age-by-task-load interaction in the retrosplenial pCC (C) and posterior parahippocampus (D), with older adults showing relatively decreased deactivation with increasing task load (see also Fig. 7) when compared to younger subjects (see Supplementary materials for details). Middlesagittal (x = 0, A, B, C, F, G) and axial sections (z = \u22129, D) of the T1 template with overlaid deactivation t-maps. 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{"pdf_hash": "c33bfb8de0f9ff7ad964840782f5955db98d6da7", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 Case 1: An 8-year-old male child presented with painful swelling in the dorsum of the right foot. a Anterior posterior (AP) plain radiograph of the right foot showing an expansive cystic lesion replacing the entire third metatarsal, except for the proximal and distal epiphyses. Diffuse endosteal thinning without a fracture, leaving the cortex as a thin shell with \u2018\u2018a balloon\u2019\u2019 appearance, caused a pressure effect on the nearby metatarsals. b Transverse T2 MRI views of the right foot showing fluid level and hemorrhage", "width": 1034, "height": 450, "subcaptions": {"a": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86], "b": [87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100], "c": [0]}, "subfigures": [{"id": "69805a26-2578-4afc-bfe5-12e9fdad0119", "label": "a", "points": [[3.7, 17.8], [3.7, 414.7], [542.8, 414.7], [542.8, 17.8]], "color": "yellow"}, {"id": "aafe7079-1d6f-4289-b873-96d447746674", "label": "b", "points": [[542.8, 1.4], [542.8, 424.5], [815.6, 424.5], [815.6, 1.4]], "color": "cyan"}, {"id": 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{"pdf_hash": "67480e4b7ca7166b8486f91ff7f560d2d4872c83", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Sulcal reconstruction and identification. Principles and application for two randomly chosen patients (with or without visual symptoms during auras). After segmentation of brain voxels, grey and white matter voxels are determined and sulci skeletons reconstructed (top). Afterwards, sulci are identified. For the two patients, the calcarine sulcus is outlined with red arrows on native brain MRI. Three-dimensional reconstruction of the calcarine sulcus is shown for both sides. Note the difference in shape between the left and right calcarine sulci in the patient without visual symptoms during auras compared with the symmetry of both sides in the patient with visual symptoms during attacks.", "width": 1414, "height": 966, "subcaptions": {"a": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "b": [84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103], "c": [104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119]}, "subfigures": [{"id": "5c5dc7d7-3958-4449-99f8-f83a4ce38b7a", "label": "a", "points": [[11.5, 2.2], [11.5, 315], [1403.2, 315], [1403.2, 2.2]], "color": "yellow"}, {"id": "db65c55c-3e47-4eca-9ff6-8513182a5230", "label": "c", "points": [[11.5, 323.9], [11.5, 596.4], [1409.9, 596.4], [1409.9, 323.9]], "color": "cyan"}, {"id": "7029c783-16cc-4612-954e-0b53177a7ab5", "label": "b", "points": [[16, 634.4], [16, 956.1], [1405.5, 956.1], [1405.5, 634.4]], "color": 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{"pdf_hash": "a1252d5a7ae497bec1a824f2e19fa257161df1ad", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2: Immunohistochemistry expression hnRNPK & Claudin-4 in eHCC and adjacent liver. (A) Cirrhotic liver nodules are showing nuclear hnRNPK (in focus), (IHC, DAB, \u00d7100). (B) High grade (G23) early HCC (eHCC), showing nuclear (in focus) and cytoplasmic hnRNPK expression, (IHC, DAB, \u00d7200).(C) Low grade (G1) early HCC (eHCC) and cirrhotic liver nodules with foci of weak cytoplasmic Claudin-4 (in focus), compared to normal moderate Claudin-4 in proliferated bile ductules (as an internal control) (IHC, DAB, \u00d7200). (D) High grade (G2) early HCC (eHCC) shows weak cytoplasmic Claudin-4 (in focus), (IHC, DAB, \u00d7100)", "width": 674, "height": 728, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "b": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67], "c": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116], "d": [117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145]}, "subfigures": [{"id": "3b7326a3-0dbb-4964-b5e3-49d12be69f5a", "label": "a", "points": [[1.6, 24.5], [1.6, 355.6], [329.6, 355.6], [329.6, 24.5]], "color": "yellow"}, {"id": "be10c242-0f61-4845-9726-e20c66ea581d", "label": "b", "points": 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{"pdf_hash": "826c21964aa7a410a04f805e002edac6354d057f", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Solitary fibrous tumor in a 16-year-old boy. A, Transverse sonogram obtained over the lateral aspect of the elbow showing a hypo - echoic solid ovoid mass (arrows) in the lateral aspect of the lateral head of the distal triceps brachii muscle (LHT), abutting the superficial fascia of the triceps. 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{"pdf_hash": "4a3cfcac2ff3a059e0820d1ba2cb06648606b766", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Figure 5 | (a) SEM image of the as-synthesized 3D TiO 2 /WO 3 mesoporous networks. (b) EDS spectroscopy of the sample. (c) and (d) EDS elemental mapping of Ti and W, respectively. (e) and (f) Low-magnification TEM and HRTEM images, respectively.", "width": 688, "height": 546, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29], "c": [32, 37, 38, 39, 40, 41, 30, 31], "d": [34, 35, 36, 37, 38, 39, 40, 43], "e": [47, 48, 49, 54, 55, 56, 57, 60], "f": [51, 52, 53, 54, 55, 56, 59, 60]}, "subfigures": [{"id": "4035bf90-0a90-4cc6-9e96-8f8bf0192a23", "label": "a", "points": [[2.5, 4.2], [2.5, 259.6], [347, 259.6], [347, 4.2]], "color": "yellow"}, {"id": "d59642c3-b227-41e4-9262-66457d425116", "label": "b", "points": [[687.2, 115.1], [687.2, -1.2], [356.8, -1.2], [356.8, 115.1]], "color": "cyan"}, {"id": "a2e7b81b-9df6-49e1-9142-68f50076b207", "label": "e", "points": [[4.7, 262.9], [4.7, 517.2], [344.8, 517.2], [344.8, 262.9]], "color": "tomato"}, {"id": "13412c39-18bb-4528-bd0d-063d0f62f9c4", "label": "c", "points": [[351.4, 124.8], [351.4, 258.5], [517.6, 258.5], [517.6, 124.8]], "color": "springgreen"}, {"id": "cf54e6d1-674b-45cc-aab9-44f6ed5e9967", "label": "c", "points": [[523.1, 131.4], [523.1, 253.1], [683.9, 253.1], [683.9, 131.4]], "color": "tomato"}, {"id": "41bebcbf-6dd6-4c9b-b2a8-6b23de0690e5", "label": "e", "points": [[354.6, 268.3], [354.6, 519.4], [683.9, 519.4], [683.9, 268.3]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": "|", "start": 9, "end": 10, "id": 2}, {"text": "(", "start": 11, "end": 12, "id": 3}, {"text": "a", "start": 12, "end": 13, "id": 4}, {"text": ")", "start": 13, "end": 14, "id": 5}, {"text": "SEM", "start": 15, "end": 18, "id": 6}, {"text": "image", "start": 19, "end": 24, "id": 7}, {"text": "of", "start": 25, "end": 27, "id": 8}, {"text": "the", "start": 28, "end": 31, "id": 9}, {"text": "as", "start": 32, "end": 34, "id": 10}, {"text": "-", "start": 34, "end": 35, "id": 11}, {"text": "synthesized", "start": 35, "end": 46, "id": 12}, {"text": "3D", "start": 47, "end": 49, "id": 13}, {"text": "TiO", "start": 50, "end": 53, "id": 14}, {"text": "2", "start": 54, "end": 55, "id": 15}, {"text": "/WO", "start": 56, "end": 59, "id": 16}, {"text": "3", "start": 60, "end": 61, "id": 17}, {"text": "mesoporous", "start": 62, "end": 72, "id": 18}, {"text": "networks", "start": 73, "end": 81, "id": 19}, {"text": ".", "start": 81, "end": 82, "id": 20}, {"text": "(", "start": 83, "end": 84, "id": 21}, {"text": "b", "start": 84, "end": 85, "id": 22}, {"text": ")", "start": 85, "end": 86, "id": 23}, {"text": "EDS", "start": 87, "end": 90, "id": 24}, {"text": "spectroscopy", "start": 91, "end": 103, "id": 25}, {"text": "of", "start": 104, "end": 106, "id": 26}, {"text": "the", "start": 107, "end": 110, "id": 27}, {"text": "sample", "start": 111, "end": 117, "id": 28}, {"text": ".", "start": 117, "end": 118, "id": 29}, {"text": "(", "start": 119, "end": 120, "id": 30}, {"text": "c", "start": 120, "end": 121, "id": 31}, {"text": ")", "start": 121, "end": 122, "id": 32}, {"text": "and", "start": 123, "end": 126, "id": 33}, {"text": "(", "start": 127, "end": 128, "id": 34}, {"text": "d", "start": 128, "end": 129, "id": 35}, {"text": ")", "start": 129, "end": 130, "id": 36}, {"text": "EDS", "start": 131, "end": 134, "id": 37}, {"text": "elemental", "start": 135, "end": 144, "id": 38}, {"text": "mapping", "start": 145, "end": 152, "id": 39}, {"text": "of", "start": 153, "end": 155, "id": 40}, {"text": "Ti", "start": 156, "end": 158, "id": 41}, {"text": "and", "start": 159, "end": 162, "id": 42}, {"text": "W", "start": 163, "end": 164, "id": 43}, {"text": ",", "start": 164, "end": 165, "id": 44}, {"text": "respectively", "start": 166, "end": 178, "id": 45}, {"text": ".", "start": 178, "end": 179, "id": 46}, {"text": "(", "start": 180, "end": 181, "id": 47}, {"text": "e", "start": 181, "end": 182, "id": 48}, {"text": ")", "start": 182, "end": 183, "id": 49}, {"text": "and", "start": 184, "end": 187, "id": 50}, {"text": "(", "start": 188, "end": 189, "id": 51}, {"text": "f", "start": 189, "end": 190, "id": 52}, {"text": ")", "start": 190, "end": 191, "id": 53}, {"text": "Low", "start": 192, "end": 195, "id": 54}, {"text": "-", "start": 195, "end": 196, "id": 55}, {"text": "magnification", "start": 196, "end": 209, "id": 56}, {"text": "TEM", "start": 210, "end": 213, "id": 57}, {"text": "and", "start": 214, "end": 217, "id": 58}, {"text": "HRTEM", "start": 218, "end": 223, "id": 59}, {"text": "images", "start": 224, "end": 230, "id": 60}, {"text": ",", "start": 230, "end": 231, "id": 61}, {"text": "respectively", "start": 232, "end": 244, "id": 62}, {"text": ".", "start": 244, "end": 245, "id": 63}]}
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{"pdf_hash": "fcdf992a8f4c840dcc135e995697dd0e5d1ba2b1", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Radiotherapy has a good effect on advanced liver cancer. a-d Intensity-modulated radiotherapy (IMRT) was used to deliver 5000 cGy to the planning target volume (PTV) in 25 fractions, given once a day over 32 days. a CT scans before treatment (left) and at 2 months after treatment (right). b CT scans before treatment (left) and at 3 months after treatment (right). c CT scans before treatment (left), at 3 months after treatment, and at 10 months after combination transarterial chemoembolization(TACE) treatment (right). d CT scans before treatment (left) and at 3 months and at 8 months after treatment (right)", "width": 1342, "height": 1486, "subcaptions": {"a": [49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "b": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84], "c": [85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 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{"pdf_hash": "c1d8319b2955cd0015d2624f92e1b9d1543881d1", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Figure 4 Male age 34 with HD. (a) CT scan pretreatment: mass of paratracheal nodes. (b) CT scan post treatment: residual R paratracheal mass of fibrous tissue (conflrmed at thoracotomy).", "width": 874, "height": 1198, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40]}, "subfigures": [{"id": "fb38ae20-12b5-4884-adc7-04148d43db00", "label": "a", "points": [[68.1, 5.3], [68.1, 553.5], [860.5, 553.5], [860.5, 5.3]], "color": "yellow"}, {"id": "ebd547a5-62de-4e95-b985-d1005c773f8e", "label": "b", "points": [[65.3, 613.5], [65.3, 1168.5], [848.1, 1168.5], [848.1, 613.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "Male", "start": 9, "end": 13, "id": 2}, {"text": "age", "start": 14, "end": 17, "id": 3}, {"text": "34", "start": 18, "end": 20, "id": 4}, {"text": "with", "start": 21, "end": 25, "id": 5}, {"text": "HD", "start": 26, "end": 28, "id": 6}, {"text": ".", "start": 28, "end": 29, "id": 7}, {"text": "(", "start": 30, "end": 31, "id": 8}, {"text": "a", "start": 31, "end": 32, "id": 9}, {"text": ")", "start": 32, "end": 33, "id": 10}, {"text": "CT", "start": 34, "end": 36, "id": 11}, {"text": "scan", "start": 37, "end": 41, "id": 12}, {"text": "pretreatment", "start": 42, "end": 54, "id": 13}, {"text": ":", "start": 54, "end": 55, "id": 14}, {"text": "mass", "start": 56, "end": 60, "id": 15}, {"text": "of", "start": 61, "end": 63, "id": 16}, {"text": "paratracheal", "start": 64, "end": 76, "id": 17}, {"text": "nodes", "start": 77, "end": 82, "id": 18}, {"text": ".", "start": 82, "end": 83, "id": 19}, {"text": "(", "start": 84, "end": 85, "id": 20}, {"text": "b", "start": 85, "end": 86, "id": 21}, {"text": ")", "start": 86, "end": 87, "id": 22}, {"text": "CT", "start": 88, "end": 90, "id": 23}, {"text": "scan", "start": 91, "end": 95, "id": 24}, {"text": "post", "start": 96, "end": 100, "id": 25}, {"text": "treatment", "start": 101, "end": 110, "id": 26}, {"text": ":", "start": 110, "end": 111, "id": 27}, {"text": "residual", "start": 112, "end": 120, "id": 28}, {"text": "R", "start": 121, "end": 122, "id": 29}, {"text": "paratracheal", "start": 123, "end": 135, "id": 30}, {"text": "mass", "start": 136, "end": 140, "id": 31}, {"text": "of", "start": 141, "end": 143, "id": 32}, {"text": "fibrous", "start": 144, "end": 151, "id": 33}, {"text": "tissue", "start": 152, "end": 158, "id": 34}, {"text": "(", "start": 159, "end": 160, "id": 35}, {"text": "conflrmed", "start": 160, "end": 169, "id": 36}, {"text": "at", "start": 170, "end": 172, "id": 37}, {"text": "thoracotomy", "start": 173, "end": 184, "id": 38}, {"text": ")", "start": 184, "end": 185, "id": 39}, {"text": ".", "start": 185, "end": 186, "id": 40}]}
{"pdf_hash": "032cfda93499651ce99e7fac4392a1f4a5236791", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIGURE 2. c) Airway wall measurement using the full-width at half-maximum algorithm. A representative x-ray attenuation curve for a ray that passes from the lumen through the airway wall and into the parenchyma is shown. The thickness of the wall is determined using the half-maximum point of the change in x-ray attenuation as the ray enters and exits the wall. A representative computed tomography image (a) and a magnified view of an airway (b) are shown. The rays can be seen to start at the lumen boundary of the wall and extend to the outer edge. Of note, some rays extend into the pulmonary artery because the artery has similar x-ray attenuation values as the airway wall. Those rays are manually deleted and the outer airway border is estimated from the remaining rays using a mathematical spline function. 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{"pdf_hash": "f436fbe54e141fc5de7e04465f0b9b9bc89f70d7", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1A,B: Chest CT showing bilateral separate nodules.", "width": 688, "height": 582, "subcaptions": {"a": [0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11]}, "subfigures": [{"id": "b95652fc-f09d-49c6-b12f-acdc370d6eef", "label": "a", "points": [[3.4, -0.4], [3.4, 550.7], [351.3, 550.7], [351.3, -0.4]], "color": "yellow"}, {"id": "244f2620-ba77-4d80-bfa1-45ac083ea6fe", "label": "a", "points": [[354.5, 2.9], [354.5, 551.8], [684.9, 551.8], [684.9, 2.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1A", "start": 7, "end": 9, "id": 1}, {"text": ",", "start": 9, "end": 10, "id": 2}, {"text": "B", "start": 10, "end": 11, "id": 3}, {"text": ":", "start": 11, "end": 12, "id": 4}, {"text": "Chest", "start": 13, "end": 18, "id": 5}, {"text": "CT", "start": 19, "end": 21, "id": 6}, {"text": "showing", "start": 22, "end": 29, "id": 7}, {"text": "bilateral", "start": 30, "end": 39, "id": 8}, {"text": "separate", "start": 40, "end": 48, "id": 9}, {"text": "nodules", "start": 49, "end": 56, "id": 10}, {"text": ".", "start": 56, "end": 57, "id": 11}]}
{"pdf_hash": "e6775346b75249ea65ea1c62b9191c906ac49c21", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. Woman 51 years of age, screening mammography of the left breast. (a) Microcalcifi cation lesion in the upper outer quadrant of the left breast (white arrow). (b) Spot compression magnifi cation mammogram of BI-RADS 5 microcalcifi cation lesion. (c) Transverse contrast-enhanced T1 FLASH 3D MRI, subtraction image. Stippled, clumped and heterogeneous enhancement of microcalcifi cation lesion (white arrows). (d) Breast MRI, time to intensity curve. Rapid initial rise and the washout pattern (type 3) of enhancement. 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{"pdf_hash": "a5ea0acbb4884909411af20fffb154ec2a289371", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. Pathologic characteristics of EBV-positive DLBCL of the elderly. (A): EBV-positive DLBCL of the elderly infiltrating soft tissue. Hematoxylin and eosin, \u03eb100. (B): Monomorphic pattern displaying large cells with immunoblastic features, characterized by central prominent nucleoli. Hematoxylin and eosin, \u03eb400. (C): Polymorphic pattern displaying large cells admixed with abundant reactive inflammatory cells, mainly small lymphocytes. Hematoxylin and eosin, \u03eb400. (D): CD20. Positivity for CD20 is consistent with a B-cell lineage. Immunohistochemistry, \u03eb400. (E): MUM-1 (nuclear pattern). Most EBV-positive DLBCL of the elderly are positive for MUM-1, consistent with a nongerminal center cell phenotype. Immunohistochemistry, \u03eb400. (F): EBV-encoded RNA (EBER) (nuclear pattern). In situ hybridization, \u03eb400. 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{"pdf_hash": "d19159e39f17aeff7e76cc2a5c00fb08882aaeaa", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 (a, b) Representative findings of patient 5. Pain and paresthesia remained in the left arm of a 52-year-old man who had undergone laminoplasty from C3 to C7 for cervical spondylotic myelopathy. (a) CT-myelogram demonstrated disc bulging and spur formation in the left neural foramen (black arrow) at the C5\u20136 level. 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{"pdf_hash": "edaa66b9ed1a23cf4fcc9ab30d73ca3a1fcab096", "fig_key": "Figure16", "fig_uri": "11-Figure16-1.png", "text": "Fig . 16.- Case 12 . Ventricular shunt function in 37-week-gestation infant with meningomyelocele and mild head enlargement. Axial ( A) and coronal (8 ) views at age 2 \u00b7 days. Moderate to severe d1latal10n of lateral (LV) and third (V3) ventric les . Septum pellucidum (SP). Follow-up examina tion (C and D) 9 days tater after temporary vent ricular shunt. Lateral and third vent ri cles diminished, a lthough still mi ldly enlarged . Further fo llow-up 2 weeks later because increasing head size suggested shunt malfunction. E and F . Inc reased vent ricular size. Malfunctioning shunt (S) r eplaced . G and H . Postoperative examination 1 month later . Ventricles collapsed and slitlike . 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{"pdf_hash": "a004637be3a14e1f9a0e34d702deabd3677bfc03", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1: (a) Bilateral pediatric testicular tumors before surgery. (b) Seven months after left radical orchiectomy on T1WI. (c) T2-trim MRI sequences visualize the right testicular tumor image after the first surgery. (d) Endodermal sinus-like in the left testicular mass (Schiller-Duval body). (e) Microcystic pattern in the left testicular mass. (f) Corneous flakes and squamous epithelial cells in the right testicular mass. 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{"pdf_hash": "5e3feedd7dc1d27d372b759c3854ddfe95999818", "fig_key": "Figure7", "fig_uri": "8-Figure7-1.png", "text": "Figure 7. Autoradiographical localization of [3H]CCK8 binding sites in lo-pm sagittal sections of brain (A and B) and in pancreas (C and D) with darkfield optics. CaZibrution bars = 200 pm. A, Cortex occipitalis (CO)-note the intense labeling in layers III and IV (s) and the virtual absence of labeling in the adjacent brachium colliculi superioris (SC). B, Cerebellum-this region contains virtually background levels of labeling. gr, lamina granularis; mol, lamina molecularis; my, myelin. 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{"pdf_hash": "008e0a5481cb7d943dbb7b57c299027be2a40c2b", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Osteochondral lesions of bilateral femoral heads in 20-year-old female. F. Coronal T1-weighted MRI (TR/TE, 374/20) (T1WI) and sagittal T2-weighted MRI (TR/TE, 1500/29) (T2WI) show similar lesion, which manifested in right femoral head. G. MRI of local referral hospital obtained 2 months before first visit to our hospital. Coronal T1WI (TR/TE, 666/12) shows wedge shaped area of hypointensity in superomedial portion of left femoral head (arrow). Coronal T2WI with fat suppression (TR/TE, 4460/57) shows corresponding area of hyperintensity (arrow). Overlying articular cartilage is difficult to observe on these images. Subchondral cysts are seen in right femoral head. 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{"pdf_hash": "66d5a7773409f48a9221cf149d7dabc69de54b58", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Brain magnetic resonance angiography showing an occlusion of the left middle cerebral artery (MCA) (arrow) on the day of stroke. (B) Brain computed tomography (CT) revealed no new abnormalities on the day of the stroke. (C) CT scan 6 days after the stroke revealed the presence of an infarction in the supply area of the MCA (arrowhead).", "width": 1362, "height": 432, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "c": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77]}, "subfigures": [{"id": "b845da28-6602-4656-aa04-790cfde48469", "label": "a", "points": [[5.4, 4.5], [5.4, 430.5], [444.4, 430.5], [444.4, 4.5]], "color": "yellow"}, {"id": "597cbfe5-7b63-4203-b0cf-8dea7ab2d7d0", "label": "b", "points": [[491.7, 19.5], [491.7, 417.6], [900.5, 417.6], [900.5, 19.5]], "color": "cyan"}, {"id": "760bd8a9-5806-421d-a8c7-586b26fdc648", "label": "c", "points": [[971.5, 17.4], [971.5, 419.8], [1346, 419.8], [1346, 17.4]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, 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{"pdf_hash": "3fb6fc0143af6d90def51f0a8ae3c0990b7c7773", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Representative retromode images of an eye with outer macular retinoschisis. (Top left) Fundus photograph of the right eye of a 77-year-old woman showing diffuse chorioretinal atrophy in the posterior fundus. (Top and middle right) Horizontal and vertical scans across the central fovea by optical coherence tomography (OCT) show macular retinoschisis with an inner lamellar hole in the central fovea. (Bottom) Retromode image by F10 shows a fingerprint pattern (black arrowheads) consisting of central radiating retinal striae and surrounding multiple dots (arrowhead) and lines (arrow). Many lines appear in parallel or in a whorled pattern. The inner lamellar hole is observed as a circular defect at the central fovea. 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{"pdf_hash": "0353f0f4da1193dd89fc33c130b3fc50afda42ca", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Micro-structure of mitochondria in liver in rhesus monkeys. (A) in blank control group (\u00d712 000), chromatin was evenly distributed in the nucleus of hepacytes, with clear nuclear membranes; swollen mitochondria can be seen inside cells; and rough endoplasmic reticulum was mildly dilated. (B) in AZT 50 mg/kg group (\u00d712 000), compared with A, chromatin was slightly condensated with clear nuclear membranes; intracytoplasmic mitochondria was swollen at varied extents; and the glycogen particles were rich. (C) in metacavir 120 mg/kg group (\u00d712 000), three months after the start of dosing, in hepatytes, nuclear chromatin was slightly condensated with clear nuclear membranes; intracytoplasmic mitochondria was swollen; and some glycogen particles disappeared. 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{"pdf_hash": "4ab7fee0fd05e3d9acc30b07795c7ca48745b09b", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "FIGURE 5. Cell death occurred by apoptosis in xenograft tumors. Two methods were used to determine whether apoptosis was the mechanism of cell death in Y79 xenograft tumor cells. Sections were taken from tumors after treatment with MO, calcitriol, or 16,23-D 3 , and stained with either H&E to examine nuclear morphology or the 3\u0408-overhang ligation technique to assess the nature of the DNA fragmentation found in dying cells. (A) H&E-stained section from a tumor treated for 5 weeks with 16,23-D 3 . The nuclei in dying cells were either pyknotic (\u2731) or in various stages of fragmentation (arrows). (B) Fluorescence micrograph of dying cells in tumor treated with 16,23-D 3 for 5 weeks, labeled by 3\u0408-overhang ligation. 40 This technique ligates a biotin-tagged DNA PCR fragment with 3\u0408-overhanging nucleotides to fragmented DNA in nuclei with similar 3\u0408-overhanging ends. Dying cells in the xenograft tumors were strongly positive. In this experiment, the proportion of cells that stained with the ligation technique was similar to the proportion of cells that stained by TUNEL in adjacent sections. 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{"pdf_hash": "263d16af58f3ba279866b91607769178ea580e2f", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIGURE 2 | Spine MRI before and after 7 months of metronomic chemotherapy. MRI evidence of disseminated leptomeningeal tumor in pre-treatment T1-weighted gadolinium enhanced sagittal view (A) disappeared after 7 months of metronomic chemotherapy (B).", "width": 1098, "height": 624, "subcaptions": {"a": [3, 4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 24, 25, 26, 27, 28, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "07a8f0fe-55b3-4551-989b-86aa4c006932", "label": "a", "points": [[37.4, 18.8], [37.4, 613.8], [538.7, 613.8], [538.7, 18.8]], "color": "yellow"}, {"id": "ab5dd419-d62b-47bc-8b46-e867d3ef1125", "label": "b", "points": [[559.5, 18.8], [559.5, 617.2], [1059, 617.2], [1059, 18.8]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "|", "start": 9, "end": 10, "id": 2}, {"text": "Spine", "start": 11, "end": 16, "id": 3}, {"text": "MRI", "start": 17, "end": 20, "id": 4}, {"text": "before", "start": 21, "end": 27, "id": 5}, {"text": "and", "start": 28, "end": 31, "id": 6}, {"text": "after", "start": 32, "end": 37, "id": 7}, {"text": "7", "start": 38, "end": 39, "id": 8}, {"text": "months", "start": 40, "end": 46, "id": 9}, {"text": "of", "start": 47, "end": 49, "id": 10}, {"text": "metronomic", "start": 50, "end": 60, "id": 11}, {"text": "chemotherapy", "start": 61, "end": 73, "id": 12}, {"text": ".", "start": 73, "end": 74, "id": 13}, {"text": "MRI", "start": 75, "end": 78, "id": 14}, {"text": "evidence", "start": 79, "end": 87, "id": 15}, {"text": "of", "start": 88, "end": 90, "id": 16}, {"text": "disseminated", "start": 91, "end": 103, "id": 17}, {"text": "leptomeningeal", "start": 104, "end": 118, "id": 18}, {"text": "tumor", "start": 119, "end": 124, "id": 19}, {"text": "in", "start": 125, "end": 127, "id": 20}, {"text": "pre", "start": 128, "end": 131, "id": 21}, {"text": "-", "start": 131, "end": 132, "id": 22}, {"text": "treatment", "start": 132, "end": 141, "id": 23}, {"text": "T1-weighted", "start": 142, "end": 153, "id": 24}, {"text": "gadolinium", "start": 154, "end": 164, "id": 25}, {"text": "enhanced", "start": 165, "end": 173, "id": 26}, {"text": "sagittal", "start": 174, "end": 182, "id": 27}, {"text": "view", "start": 183, "end": 187, "id": 28}, {"text": "(", "start": 188, "end": 189, "id": 29}, {"text": "A", "start": 189, "end": 190, "id": 30}, {"text": ")", "start": 190, "end": 191, "id": 31}, {"text": "disappeared", "start": 192, "end": 203, "id": 32}, {"text": "after", "start": 204, "end": 209, "id": 33}, {"text": "7", "start": 210, "end": 211, "id": 34}, {"text": "months", "start": 212, "end": 218, "id": 35}, {"text": "of", "start": 219, "end": 221, "id": 36}, {"text": "metronomic", "start": 222, "end": 232, "id": 37}, {"text": "chemotherapy", "start": 233, "end": 245, "id": 38}, {"text": "(", "start": 246, "end": 247, "id": 39}, {"text": "B", "start": 247, "end": 248, "id": 40}, {"text": ")", "start": 248, "end": 249, "id": 41}, {"text": ".", "start": 249, "end": 250, "id": 42}]}
{"pdf_hash": "93b7fdd08a4b2716d65ad135b04d13ec67951154", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig. 5 a\u2013d Use of prone chest CT to distinguish a lung nodule from subsegmental atelectasis. a Axial chest CT image taken in the supine position of a 9-yearold boy with anaplastic large cell lymphoma shows subpleural nodular opacity (arrow) in the dependent portion of the left lower lobe. b Prone CT image demonstrates disappearance of the subpleural nodular opacity indicating that the opacity seen on supine CT represented subsegmental atelectasis. c Axial chest CT image taken in the supine position of a 6-year-old boy with hepatoblastoma shows a lung nodule (arrow) in the right basal lung that needs to be distinguished from dependent opacity. d Prone CT image unequivocally reveals a tiny metastatic lung nodule (arrow)", "width": 1052, "height": 708, "subcaptions": {"b": [56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78], 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{"pdf_hash": "907507b12bc5cee82c4d9b1c9f8cc2adff19d2c1", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Colonoscopy and histologic findings in duodenum. (A) The diffuse erosive ulcers and bleeding in the descending duodenum. (B) Inflammation in the mucous membrane with superficial erosion.", "width": 1248, "height": 608, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "ab2df5ca-2b30-44a7-9544-3f98ba2ba612", "label": "a", "points": [[47.6, 24.3], [47.6, 576.4], [603.6, 576.4], [603.6, 24.3]], "color": "yellow"}, {"id": "b33d1d08-f041-4c85-8581-5c2dafa90eeb", "label": "b", "points": [[660.8, 22.3], [660.8, 576.4], [1220.8, 576.4], [1220.8, 22.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Colonoscopy", "start": 10, "end": 21, "id": 3}, {"text": "and", "start": 22, "end": 25, "id": 4}, {"text": "histologic", "start": 26, "end": 36, "id": 5}, {"text": "findings", "start": 37, "end": 45, "id": 6}, {"text": "in", "start": 46, "end": 48, "id": 7}, {"text": "duodenum", "start": 49, "end": 57, "id": 8}, {"text": ".", "start": 57, "end": 58, "id": 9}, {"text": "(", "start": 59, "end": 60, "id": 10}, {"text": "A", "start": 60, "end": 61, "id": 11}, {"text": ")", "start": 61, "end": 62, "id": 12}, {"text": "The", "start": 63, "end": 66, "id": 13}, {"text": "diffuse", "start": 67, "end": 74, "id": 14}, {"text": "erosive", "start": 75, "end": 82, "id": 15}, {"text": "ulcers", "start": 83, "end": 89, "id": 16}, {"text": "and", "start": 90, "end": 93, "id": 17}, {"text": "bleeding", "start": 94, "end": 102, "id": 18}, {"text": "in", "start": 103, "end": 105, "id": 19}, {"text": "the", "start": 106, "end": 109, "id": 20}, {"text": "descending", "start": 110, "end": 120, "id": 21}, {"text": "duodenum", "start": 121, "end": 129, "id": 22}, {"text": ".", "start": 129, "end": 130, "id": 23}, {"text": "(", "start": 131, "end": 132, "id": 24}, {"text": "B", "start": 132, "end": 133, "id": 25}, {"text": ")", "start": 133, "end": 134, "id": 26}, {"text": "Inflammation", "start": 135, "end": 147, "id": 27}, {"text": "in", "start": 148, "end": 150, "id": 28}, {"text": "the", "start": 151, "end": 154, "id": 29}, {"text": "mucous", "start": 155, "end": 161, "id": 30}, {"text": "membrane", "start": 162, "end": 170, "id": 31}, {"text": "with", "start": 171, "end": 175, "id": 32}, {"text": "superficial", "start": 176, "end": 187, "id": 33}, {"text": "erosion", "start": 188, "end": 195, "id": 34}, {"text": ".", "start": 195, "end": 196, "id": 35}]}
{"pdf_hash": "d6f903e860de181197c440b1eca61695385122cc", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Figure 5 (A) Forward-looking optical coherence tomography image acquired ex vivo of a peripheral chronic total occlusion (CTO). The image planes lies just below the surface of the CTO\u2019s cap. (B) The corresponding histology with Masson\u2019s Trichrome. (C) A longitudinal image reconstructed in a plane perpendicular to the white line seen in panel A. The white arrows delineate the external elastic lamina. The arrowheads are surface reflection artefacts at the air/tissue interface of the proximal cap. 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{"pdf_hash": "a42e8103c4e93a4a3ad25754616f11551a3503da", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Endoscopic images of the main lesion (single arrow) and the satellite lesion (double arrows) of early gastric cancer. 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{"pdf_hash": "36df41c88d0bfe43ae61942940f6d18362f19410", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1A\u2013B Measurement parameters are presented in these illustrations. (A) The dashed line represents the appropriate angulation on a reformatted workstation for obtaining the transverse CT image for each vertebra displaying both pedicles. (B) The dashed line represents the axis of the vertebra; the guideline was defined as the straight-line perpendicular to the axis of the vertebra that passed through the anterior tip of the vertebral canal. 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{"pdf_hash": "8cebfeafa69d1e9485c8603e402e52074c2d7a17", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Entheseal-related bone changes shown by (A) an osteoarthritic distal interphalangeal (DIP) joint scanned using T2-weighted fat-suppressed coronal sequence (B) a T1-weighted coronal image of a different DIP joint and (C) the corresponding post-gadolinium image showing a bone erosion that enhances after contrast (open arrows). (A) Thickened ligaments, which were degenerative bilaterally with fraying at the enthesis, can be seen (arrowheads). Prominent bone oedema is seen on the proximal phalange (arrow), which has high signal. This oedema has a relationship with the ligament that articulates with the adjacent bone as shown in fig 2. (B, C) As in the case of bone oedema, erosions are commonly related to the collateral ligaments being present adjacent to the ligament (arrow heads). 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{"pdf_hash": "b44d19faf56dbacab7910a0809c36439aa815d6e", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3. Axial magnetic resonance imaging (MRI) of an osteochondrolipoma in the left scapular region. (A) T1-weighted sequence showing the mass with an almost homogeneous high signal intensity. (B) T2-weighted sequence showing the mass with almost homogeneous high signal intensity. (C) Contrast-enhanced fat-suppressed T1-weighted sequence showing a faint peripheral and septal enhancement of the mass.", "width": 446, "height": 998, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "c": [50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71]}, "subfigures": [{"id": "5498c97e-a10f-4245-9710-43a862f75fc0", "label": "a", "points": [[28.8, 7.9], [28.8, 337.9], [445.8, 337.9], [445.8, 7.9]], "color": "yellow"}, {"id": "a7e32786-7160-4d8e-b689-9f24b74dbd13", "label": "b", "points": [[31.8, 345.9], [31.8, 651.9], [442.8, 651.9], [442.8, 345.9]], "color": "cyan"}, {"id": "8e44878c-d62e-4a2b-82ca-788e23862207", "label": "c", "points": [[28.8, 672.9], [28.8, 994.9], [442.8, 994.9], [442.8, 672.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Axial", "start": 10, "end": 15, "id": 3}, {"text": "magnetic", "start": 16, "end": 24, "id": 4}, {"text": "resonance", "start": 25, "end": 34, "id": 5}, {"text": "imaging", "start": 35, "end": 42, "id": 6}, {"text": "(", "start": 43, "end": 44, "id": 7}, {"text": "MRI", "start": 44, "end": 47, "id": 8}, {"text": ")", "start": 47, "end": 48, "id": 9}, {"text": "of", "start": 49, "end": 51, "id": 10}, {"text": "an", "start": 52, "end": 54, "id": 11}, {"text": "osteochondrolipoma", "start": 55, "end": 73, "id": 12}, {"text": "in", "start": 74, "end": 76, "id": 13}, {"text": "the", "start": 77, "end": 80, "id": 14}, {"text": "left", "start": 81, "end": 85, "id": 15}, {"text": "scapular", "start": 86, "end": 94, "id": 16}, {"text": "region", "start": 95, "end": 101, "id": 17}, {"text": ".", "start": 101, "end": 102, "id": 18}, {"text": "(", "start": 103, "end": 104, "id": 19}, {"text": "A", "start": 104, "end": 105, "id": 20}, {"text": ")", "start": 105, "end": 106, "id": 21}, {"text": "T1-weighted", "start": 107, "end": 118, "id": 22}, {"text": "sequence", "start": 119, "end": 127, "id": 23}, {"text": "showing", "start": 128, "end": 135, "id": 24}, {"text": "the", "start": 136, "end": 139, "id": 25}, {"text": "mass", "start": 140, "end": 144, "id": 26}, {"text": "with", "start": 145, "end": 149, "id": 27}, {"text": "an", "start": 150, "end": 152, "id": 28}, {"text": "almost", "start": 153, "end": 159, "id": 29}, {"text": "homogeneous", "start": 160, "end": 171, "id": 30}, {"text": "high", "start": 172, "end": 176, "id": 31}, {"text": "signal", "start": 177, "end": 183, "id": 32}, {"text": "intensity", "start": 184, "end": 193, "id": 33}, {"text": ".", "start": 193, "end": 194, "id": 34}, {"text": "(", "start": 195, "end": 196, "id": 35}, {"text": "B", "start": 196, "end": 197, "id": 36}, {"text": ")", "start": 197, "end": 198, "id": 37}, {"text": "T2-weighted", "start": 199, "end": 210, "id": 38}, {"text": "sequence", "start": 211, "end": 219, "id": 39}, {"text": "showing", "start": 220, "end": 227, "id": 40}, {"text": "the", "start": 228, "end": 231, "id": 41}, {"text": "mass", "start": 232, "end": 236, "id": 42}, {"text": "with", "start": 237, "end": 241, "id": 43}, {"text": "almost", "start": 242, "end": 248, "id": 44}, {"text": "homogeneous", "start": 249, "end": 260, "id": 45}, {"text": "high", "start": 261, "end": 265, "id": 46}, {"text": "signal", "start": 266, "end": 272, "id": 47}, {"text": "intensity", "start": 273, "end": 282, "id": 48}, {"text": ".", "start": 282, "end": 283, "id": 49}, {"text": "(", "start": 284, "end": 285, "id": 50}, {"text": "C", "start": 285, "end": 286, "id": 51}, {"text": ")", "start": 286, "end": 287, "id": 52}, {"text": "Contrast", "start": 288, "end": 296, "id": 53}, {"text": "-", "start": 296, "end": 297, "id": 54}, {"text": "enhanced", "start": 297, "end": 305, "id": 55}, {"text": "fat", "start": 306, "end": 309, "id": 56}, {"text": "-", "start": 309, "end": 310, "id": 57}, {"text": "suppressed", "start": 310, "end": 320, "id": 58}, {"text": "T1-weighted", "start": 321, "end": 332, "id": 59}, {"text": "sequence", "start": 333, "end": 341, "id": 60}, {"text": "showing", "start": 342, "end": 349, "id": 61}, {"text": "a", "start": 350, "end": 351, "id": 62}, {"text": "faint", "start": 352, "end": 357, "id": 63}, {"text": "peripheral", "start": 358, "end": 368, "id": 64}, {"text": "and", "start": 369, "end": 372, "id": 65}, {"text": "septal", "start": 373, "end": 379, "id": 66}, {"text": "enhancement", "start": 380, "end": 391, "id": 67}, {"text": "of", "start": 392, "end": 394, "id": 68}, {"text": "the", "start": 395, "end": 398, "id": 69}, {"text": "mass", "start": 399, "end": 403, "id": 70}, {"text": ".", "start": 403, "end": 404, "id": 71}]}
{"pdf_hash": "d7233ca5b633e92bbae9c51b50d7e902a9372796", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. The transverse (A), longitudinal (B), and radial (C) grayscale ultrasonograms of the right breast taken at the upper outer quadrant show an indistinct, oval, heterogeneous-echoic mass with posterior enhancement. Longitudinal (D) and radial (E) colorDoppler sonogram show disordered and branching vessels within the mass. (F) Strain elastogram shows homogeneous blue color coding in the mass, indicating the hard, elastic nature of the mass (red depicted as soft, green as intermediate, and blue as hard). (G) The strain ratio of the mass relative to the adjacent fat tissue was 4.78, also implying the apparent hard elasticity.", "width": 624, "height": 1602, "subcaptions": {"a": [3, 4, 5, 6, 7, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "b": [3, 9, 10, 11, 12, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "c": [3, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "d": [64, 45, 46, 47, 48, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "6028eeae-6f3b-438a-ab34-a41ea0ccc25b", "label": "a", "points": [[3.7, 4.3], [3.7, 420.3], [620.7, 420.3], [620.7, 4.3]], "color": "yellow"}, {"id": "9492c2c3-31d4-4d05-aee0-6f82970eccdc", "label": "b", "points": [[4.7, 432], [4.7, 776], [626.7, 776], [626.7, 432]], "color": "cyan"}, {"id": "1907fa09-f31d-47d1-a20f-f14ccf6387dc", "label": "c", 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{"pdf_hash": "c2606133851321a6e6690b9aa50176da92243c78", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig 5. A 10-year-old female spayed cat with carcinoma at the canthus of the eye. Patient at presentation (A), and at 1 month follow-up after only 2 treatments of electrochemotherapy (B).", "width": 858, "height": 308, "subcaptions": {"a": [19, 20, 21, 22, 23, 24], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 19, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "e05b122e-2026-48bd-a634-d5d8c233d1e2", "label": "a", "points": [[3.4, 1.8], [3.4, 305.4], [349.1, 305.4], [349.1, 1.8]], "color": "yellow"}, {"id": "08dd1ce3-9fbe-4f91-b3a9-03b2747ee4b1", "label": "b", "points": [[507.7, 0.5], [507.7, 305.4], [854.7, 305.4], [854.7, 0.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "5", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "10-year", "start": 9, "end": 16, "id": 4}, {"text": "-", "start": 16, "end": 17, "id": 5}, {"text": "old", "start": 17, "end": 20, "id": 6}, {"text": "female", "start": 21, "end": 27, "id": 7}, {"text": "spayed", "start": 28, "end": 34, "id": 8}, {"text": "cat", "start": 35, "end": 38, "id": 9}, {"text": "with", "start": 39, "end": 43, "id": 10}, {"text": "carcinoma", "start": 44, "end": 53, "id": 11}, {"text": "at", "start": 54, "end": 56, "id": 12}, {"text": "the", "start": 57, "end": 60, "id": 13}, {"text": "canthus", "start": 61, "end": 68, "id": 14}, {"text": "of", "start": 69, "end": 71, "id": 15}, {"text": "the", "start": 72, "end": 75, "id": 16}, {"text": "eye", "start": 76, "end": 79, "id": 17}, {"text": ".", "start": 79, "end": 80, "id": 18}, {"text": "Patient", "start": 81, "end": 88, "id": 19}, {"text": "at", "start": 89, "end": 91, "id": 20}, {"text": "presentation", "start": 92, "end": 104, "id": 21}, {"text": "(", "start": 105, "end": 106, "id": 22}, {"text": "A", "start": 106, "end": 107, "id": 23}, {"text": ")", "start": 107, "end": 108, "id": 24}, {"text": ",", "start": 108, "end": 109, "id": 25}, {"text": "and", "start": 110, "end": 113, "id": 26}, {"text": "at", "start": 114, "end": 116, "id": 27}, {"text": "1", "start": 117, "end": 118, "id": 28}, {"text": "month", "start": 119, "end": 124, "id": 29}, {"text": "follow", "start": 125, "end": 131, "id": 30}, {"text": "-", "start": 131, "end": 132, "id": 31}, {"text": "up", "start": 132, "end": 134, "id": 32}, {"text": "after", "start": 135, "end": 140, "id": 33}, {"text": "only", "start": 141, "end": 145, "id": 34}, {"text": "2", "start": 146, "end": 147, "id": 35}, {"text": "treatments", "start": 148, "end": 158, "id": 36}, {"text": "of", "start": 159, "end": 161, "id": 37}, {"text": "electrochemotherapy", "start": 162, "end": 181, "id": 38}, {"text": "(", "start": 182, "end": 183, "id": 39}, {"text": "B", "start": 183, "end": 184, "id": 40}, {"text": ")", "start": 184, "end": 185, "id": 41}, {"text": ".", "start": 185, "end": 186, "id": 42}]}
{"pdf_hash": "d1ed65535db4415158d394f18d5eb581920b3539", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4 Control patient images. A-C: Patient 3 (no villous atrophy); D-F: Patient 4 (no villous atrophy); A, D: The grayscale endoscopic images; B, E: The threedimensional projections; C, F: Projections in false color. 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{"pdf_hash": "d5ade197653660a6cd0bad431ef6f40f3b7a6cb1", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Posteroanterior and lateral x-ray of a patient with radio-carpal arthrosis and DRUJ incongruence", "width": 696, "height": 674, "subcaptions": {"a": [3, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19]}, "subfigures": [{"id": "c391f573-b7df-4619-96ec-946efb274010", "label": "a", "points": [[4.6, 24.6], [4.6, 648], [390.5, 648], [390.5, 24.6]], "color": "yellow"}, {"id": "e72e4d28-5992-4cea-87e3-c8d4e59f20bf", "label": "b", "points": [[401.5, 32.3], [401.5, 646.9], [659.9, 646.9], [659.9, 32.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Posteroanterior", "start": 7, "end": 22, "id": 3}, {"text": "and", "start": 23, "end": 26, "id": 4}, {"text": "lateral", "start": 27, "end": 34, "id": 5}, {"text": "x", "start": 35, "end": 36, "id": 6}, {"text": "-", "start": 36, "end": 37, "id": 7}, {"text": "ray", "start": 37, "end": 40, "id": 8}, {"text": "of", "start": 41, "end": 43, "id": 9}, {"text": "a", "start": 44, "end": 45, "id": 10}, {"text": "patient", "start": 46, "end": 53, "id": 11}, {"text": "with", "start": 54, "end": 58, "id": 12}, {"text": "radio", "start": 59, "end": 64, "id": 13}, {"text": "-", "start": 64, "end": 65, "id": 14}, {"text": "carpal", "start": 65, "end": 71, "id": 15}, {"text": "arthrosis", "start": 72, "end": 81, "id": 16}, {"text": "and", "start": 82, "end": 85, "id": 17}, {"text": "DRUJ", "start": 86, "end": 90, "id": 18}, {"text": "incongruence", "start": 91, "end": 103, "id": 19}]}
{"pdf_hash": "1b5a9b4299a97a00beae0342c8baaebabafdf209", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Transverse sections of lateral muscle of Pagellus bogaraveo aged 11 (A-C) and 23 (D) days. (A) SDH; (B and D) immunoreaction with BA-G5; (C): immunoreaction with 4-96. The superficial monolayer fibres (LSM) stain strongly for SDH, and weakly with BA-G5, whereas the new slow-red fibres (LR) close to the lateral line nerve are very strongly stained with both 4-96 and BA-G5. Fast-white (LW) muscle fibres are negative for all reactions. Li indicates liver, used as support tissue when the larvae were snap-frozen. Scale bar A, B, and C = 50 m and D = 25 m. 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{"pdf_hash": "7da5b79720ffba1dc12856524084c51ebe95be8f", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 Correlation between tumor volume depicted in multimodal imaging and dose distribution. A 82 year old patient with biopsy confirmed PCa (Gleason score 9) and an initial PSA of 8 ng/ml underwent mpMRI (a:T2w, b:ADC), PSMA PET/CT (c) and a planning CT (d) before EBRT. MpMRI depicted one lesion in the left lobe and PSMA PET depicted one lesion in the left lobe and one lesion in the right lobe. In picture D the IMRT dose-distribution with contours of the prostatic gland (red), PSMA PET (blue) and MRI (orange) are shown. 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{"pdf_hash": "56eebbecc15cd311191b9f21ffc28800261905b1", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. Intracellular localization of a PcCMPG1::GFP fusion protein without (A) and with (B) a putative nuclear localization signal (NLS) within PcCMPG1. n, nucleus; c, cytoplasm.", "width": 652, "height": 292, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [4, 5, 6, 7, 8, 9, 10, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "8ff612bc-4666-4d77-b1eb-7060ad972465", "label": "a", "points": [[9.4, 2.4], [9.4, 288.8], [329.8, 288.8], [329.8, 2.4]], "color": "yellow"}, {"id": "41b9c312-1030-4ee9-bac1-6e9975b2e382", "label": "b", "points": [[334.9, 5.5], [334.9, 288.8], [647, 288.8], [647, 5.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Intracellular", "start": 8, "end": 21, "id": 4}, {"text": "localization", "start": 22, "end": 34, "id": 5}, {"text": "of", "start": 35, "end": 37, "id": 6}, {"text": "a", "start": 38, "end": 39, "id": 7}, {"text": "PcCMPG1::GFP", "start": 40, "end": 52, "id": 8}, {"text": "fusion", "start": 53, "end": 59, "id": 9}, {"text": "protein", "start": 60, "end": 67, "id": 10}, {"text": "without", "start": 68, "end": 75, "id": 11}, {"text": "(", "start": 76, "end": 77, "id": 12}, {"text": "A", "start": 77, "end": 78, "id": 13}, {"text": ")", "start": 78, "end": 79, "id": 14}, {"text": "and", "start": 80, "end": 83, "id": 15}, {"text": "with", "start": 84, "end": 88, "id": 16}, {"text": "(", "start": 89, "end": 90, "id": 17}, {"text": "B", "start": 90, "end": 91, "id": 18}, {"text": ")", "start": 91, "end": 92, "id": 19}, {"text": "a", "start": 93, "end": 94, "id": 20}, {"text": "putative", "start": 95, "end": 103, "id": 21}, {"text": "nuclear", "start": 104, "end": 111, "id": 22}, {"text": "localization", "start": 112, "end": 124, "id": 23}, {"text": "signal", "start": 125, "end": 131, "id": 24}, {"text": "(", "start": 132, "end": 133, "id": 25}, {"text": "NLS", "start": 133, "end": 136, "id": 26}, {"text": ")", "start": 136, "end": 137, "id": 27}, {"text": "within", "start": 138, "end": 144, "id": 28}, {"text": "PcCMPG1", "start": 145, "end": 152, "id": 29}, {"text": ".", "start": 152, "end": 153, "id": 30}, {"text": "n", "start": 154, "end": 155, "id": 31}, {"text": ",", "start": 155, "end": 156, "id": 32}, {"text": "nucleus", "start": 157, "end": 164, "id": 33}, {"text": ";", "start": 164, "end": 165, "id": 34}, {"text": "c", "start": 166, "end": 167, "id": 35}, {"text": ",", "start": 167, "end": 168, "id": 36}, {"text": "cytoplasm", "start": 169, "end": 178, "id": 37}, {"text": ".", "start": 178, "end": 179, "id": 38}]}
{"pdf_hash": "6e895d2b404b5d3c8d31c7ff7a19dc80f23208cf", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2: Representative immunohistochemical sections. A. P16 strong cytoplasmic and nuclear expression. DAB x 25. B. P53 strong nuclear overexpression by all tumor cells. DAB x 100. C. CXCR4 expression by stromal cells was associated with a worse pattern of invasion. DAB x 200. D. CD20 heavily infiltrated frontal compartment. Moderately infiltrated intraepithelial compartment. DAB x 100.", "width": 1038, "height": 764, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "d": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67]}, "subfigures": [{"id": "d3c4af59-ae07-47d8-a67e-d98c60e36335", "label": "a", "points": [[4.1, 3.3], [4.1, 382.1], [528.8, 382.1], [528.8, 3.3]], "color": "yellow"}, {"id": "9b8c1931-0297-48f4-980c-1e8a286267f2", "label": "b", "points": [[538.7, 1.6], [538.7, 385.4], [1032.3, 385.4], [1032.3, 1.6]], "color": "cyan"}, {"id": "79d01314-9c30-422a-9a8c-d447fa5585e7", "label": "c", "points": [[0.8, 390.3], [0.8, 760.9], [527.2, 760.9], [527.2, 390.3]], "color": "magenta"}, {"id": "8bfd3691-a844-4ee3-948a-0d766fbb6253", "label": "d", "points": [[537, 391.9], [537, 757.6], [1029, 757.6], [1029, 391.9]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Representative", "start": 10, "end": 24, "id": 3}, {"text": "immunohistochemical", "start": 25, "end": 44, "id": 4}, {"text": "sections", "start": 45, "end": 53, "id": 5}, {"text": ".", "start": 53, "end": 54, "id": 6}, {"text": "A.", "start": 55, "end": 57, "id": 7}, {"text": "P16", "start": 58, "end": 61, "id": 8}, {"text": "strong", "start": 62, "end": 68, "id": 9}, {"text": "cytoplasmic", "start": 69, "end": 80, "id": 10}, {"text": "and", "start": 81, "end": 84, "id": 11}, {"text": "nuclear", "start": 85, "end": 92, "id": 12}, {"text": "expression", "start": 93, "end": 103, "id": 13}, {"text": ".", "start": 103, "end": 104, "id": 14}, {"text": "DAB", "start": 105, "end": 108, "id": 15}, {"text": "x", "start": 109, "end": 110, "id": 16}, {"text": "25", "start": 111, "end": 113, "id": 17}, {"text": ".", "start": 113, "end": 114, "id": 18}, {"text": "B.", "start": 115, "end": 117, "id": 19}, {"text": "P53", "start": 118, "end": 121, "id": 20}, {"text": "strong", "start": 122, "end": 128, "id": 21}, {"text": "nuclear", "start": 129, "end": 136, "id": 22}, {"text": "overexpression", "start": 137, "end": 151, "id": 23}, {"text": "by", "start": 152, "end": 154, "id": 24}, {"text": "all", "start": 155, "end": 158, "id": 25}, {"text": "tumor", "start": 159, "end": 164, "id": 26}, {"text": "cells", "start": 165, "end": 170, "id": 27}, {"text": ".", "start": 170, "end": 171, "id": 28}, {"text": "DAB", "start": 172, "end": 175, "id": 29}, {"text": "x", "start": 176, "end": 177, "id": 30}, {"text": "100", "start": 178, "end": 181, "id": 31}, {"text": ".", "start": 181, "end": 182, "id": 32}, {"text": "C.", "start": 183, "end": 185, "id": 33}, {"text": "CXCR4", "start": 186, "end": 191, "id": 34}, {"text": "expression", "start": 192, "end": 202, "id": 35}, {"text": "by", "start": 203, "end": 205, "id": 36}, {"text": "stromal", "start": 206, "end": 213, "id": 37}, {"text": "cells", "start": 214, "end": 219, "id": 38}, {"text": "was", "start": 220, "end": 223, "id": 39}, {"text": "associated", "start": 224, "end": 234, "id": 40}, {"text": "with", "start": 235, "end": 239, "id": 41}, {"text": "a", "start": 240, "end": 241, "id": 42}, {"text": "worse", "start": 242, "end": 247, "id": 43}, {"text": "pattern", "start": 248, "end": 255, "id": 44}, {"text": "of", "start": 256, "end": 258, "id": 45}, {"text": "invasion", "start": 259, "end": 267, "id": 46}, {"text": ".", "start": 267, "end": 268, "id": 47}, {"text": "DAB", "start": 269, "end": 272, "id": 48}, {"text": "x", "start": 273, "end": 274, "id": 49}, {"text": "200", "start": 275, "end": 278, "id": 50}, {"text": ".", "start": 278, "end": 279, "id": 51}, {"text": "D.", "start": 280, "end": 282, "id": 52}, {"text": "CD20", "start": 283, "end": 287, "id": 53}, {"text": "heavily", "start": 288, "end": 295, "id": 54}, {"text": "infiltrated", "start": 296, "end": 307, "id": 55}, {"text": "frontal", "start": 308, "end": 315, "id": 56}, {"text": "compartment", "start": 316, "end": 327, "id": 57}, {"text": ".", "start": 327, "end": 328, "id": 58}, {"text": "Moderately", "start": 329, "end": 339, "id": 59}, {"text": "infiltrated", "start": 340, "end": 351, "id": 60}, {"text": "intraepithelial", "start": 352, "end": 367, "id": 61}, {"text": "compartment", "start": 368, "end": 379, "id": 62}, {"text": ".", "start": 379, "end": 380, "id": 63}, {"text": "DAB", "start": 381, "end": 384, "id": 64}, {"text": "x", "start": 385, "end": 386, "id": 65}, {"text": "100", "start": 387, "end": 390, "id": 66}, {"text": ".", "start": 390, "end": 391, "id": 67}]}
{"pdf_hash": "4cb702886240b6661e27a84490fb058c600cabfe", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. a: axial image, b: MPR. An irregular-shaped nodular shadow is seen in the right S1, with air bronchogram.", "width": 1110, "height": 588, "subcaptions": {"a": [3, 4, 5, 6], "b": [8, 9, 10]}, "subfigures": [{"id": "025e084a-d0e5-4afe-bad7-e86ed4364c8c", "label": "a", "points": [[5.3, 2.5], [5.3, 549.5], [540.1, 549.5], [540.1, 2.5]], "color": "yellow"}, {"id": "4680b53d-6e7f-42ed-8f2c-8956d7c94a40", "label": "b", "points": [[559.4, 0.7], [559.4, 556.6], [1104.7, 556.6], [1104.7, 0.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ":", "start": 11, "end": 12, "id": 4}, {"text": "axial", "start": 13, "end": 18, "id": 5}, {"text": "image", "start": 19, "end": 24, "id": 6}, {"text": ",", "start": 24, "end": 25, "id": 7}, {"text": "b", "start": 26, "end": 27, "id": 8}, {"text": ":", "start": 27, "end": 28, "id": 9}, {"text": "MPR", "start": 29, "end": 32, "id": 10}, {"text": ".", "start": 32, "end": 33, "id": 11}, {"text": "An", "start": 34, "end": 36, "id": 12}, {"text": "irregular", "start": 37, "end": 46, "id": 13}, {"text": "-", "start": 46, "end": 47, "id": 14}, {"text": "shaped", "start": 47, "end": 53, "id": 15}, {"text": "nodular", "start": 54, "end": 61, "id": 16}, {"text": "shadow", "start": 62, "end": 68, "id": 17}, {"text": "is", "start": 69, "end": 71, "id": 18}, {"text": "seen", "start": 72, "end": 76, "id": 19}, {"text": "in", "start": 77, "end": 79, "id": 20}, {"text": "the", "start": 80, "end": 83, "id": 21}, {"text": "right", "start": 84, "end": 89, "id": 22}, {"text": "S1", "start": 90, "end": 92, "id": 23}, {"text": ",", "start": 92, "end": 93, "id": 24}, {"text": "with", "start": 94, "end": 98, "id": 25}, {"text": "air", "start": 99, "end": 102, "id": 26}, {"text": "bronchogram", "start": 103, "end": 114, "id": 27}, {"text": ".", "start": 114, "end": 115, "id": 28}]}
{"pdf_hash": "df92245cbec1006de99342d35dc0a8e56ae57c4e", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Fig 2. MRI study of cyst disappearance. A. Sagittal T2WI MRI shows cysts before fibrin gel therapy. B. Sagittal T2WI MRI obtained 24 months after operation shows that the cysts disappeared completely. doi:10.1371/journal.pone.0118254.g002", "width": 1040, "height": 634, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "09dc219d-2c6e-4602-8ccd-b11114ad5336", "label": "a", "points": [[3.3, 3.3], [3.3, 607.9], [511, 607.9], [511, 3.3]], "color": "yellow"}, {"id": "9bb63b87-3baa-410a-b3a5-99bf50c7ba83", "label": "b", "points": [[521.7, 4.9], [521.7, 609.8], [1031, 609.8], [1031, 4.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "MRI", "start": 7, "end": 10, "id": 3}, {"text": "study", "start": 11, "end": 16, "id": 4}, {"text": "of", "start": 17, "end": 19, "id": 5}, {"text": "cyst", "start": 20, "end": 24, "id": 6}, {"text": "disappearance", "start": 25, "end": 38, "id": 7}, {"text": ".", "start": 38, "end": 39, "id": 8}, {"text": "A.", "start": 40, "end": 42, "id": 9}, {"text": "Sagittal", "start": 43, "end": 51, "id": 10}, {"text": "T2WI", "start": 52, "end": 56, "id": 11}, {"text": "MRI", "start": 57, "end": 60, "id": 12}, {"text": "shows", "start": 61, "end": 66, "id": 13}, {"text": "cysts", "start": 67, "end": 72, "id": 14}, {"text": "before", "start": 73, "end": 79, "id": 15}, {"text": "fibrin", "start": 80, "end": 86, "id": 16}, {"text": "gel", "start": 87, "end": 90, "id": 17}, {"text": "therapy", "start": 91, "end": 98, "id": 18}, {"text": ".", "start": 98, "end": 99, "id": 19}, {"text": "B.", "start": 100, "end": 102, "id": 20}, {"text": "Sagittal", "start": 103, "end": 111, "id": 21}, {"text": "T2WI", "start": 112, "end": 116, "id": 22}, {"text": "MRI", "start": 117, "end": 120, "id": 23}, {"text": "obtained", "start": 121, "end": 129, "id": 24}, {"text": "24", "start": 130, "end": 132, "id": 25}, {"text": "months", "start": 133, "end": 139, "id": 26}, {"text": "after", "start": 140, "end": 145, "id": 27}, {"text": "operation", "start": 146, "end": 155, "id": 28}, {"text": "shows", "start": 156, "end": 161, "id": 29}, {"text": "that", "start": 162, "end": 166, "id": 30}, {"text": "the", "start": 167, "end": 170, "id": 31}, {"text": "cysts", "start": 171, "end": 176, "id": 32}, {"text": "disappeared", "start": 177, "end": 188, "id": 33}, {"text": "completely", "start": 189, "end": 199, "id": 34}, {"text": ".", "start": 199, "end": 200, "id": 35}, {"text": "doi:10.1371", "start": 201, "end": 212, "id": 36}, {"text": "/", "start": 212, "end": 213, "id": 37}, {"text": "journal.pone.0118254.g002", "start": 213, "end": 238, "id": 38}]}
{"pdf_hash": "ea41bbaf04ef2f88cef9666ea867bd97b8eccf3d", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4a\u2013d Standard slab MIP images in the postprocessing protocol make MDCTA of peripheral arteries on a routine basis feasible. Slab MIPs are easy and fast to create and to evaluate. The images depict the vasculature without superimposing bones (a and b). From the abdominal data set, MIP images are created in coronal projection to depict the renal arteries (b) and in sagittal projection to depict the celiac trunk and mesenteric arteries (d). The aorta is also depicted for evaluation. (c) Standard coronal slab MIPs from the data set of the upper legs are created, which are parallel to the superficial femoral and popliteal artery. 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{"pdf_hash": "b34520294cc9ac3df741b6597d5f9325859252a5", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Esophagogastroduodenoscopy procedure and pathologic findings of case 1. (A, B) Salvage endoscopic submucosal dissection (ESD) for metachronous recurrent superficial esophageal squamous cell carcinoma. The lesion is 32 cm from the incisors and previously treated with radiation. (C) The pathologic finding of the ESD specimen showing a well-differentiated squamous cell carcinoma with lamina propria invasion. 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{"pdf_hash": "86b6df5284818d2eb83637f96d62da7061a36677", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Endoscopic findings of the proximal antrum in the first patient (a 39 years old woman). (A) Initial findings showed micronodules measuring 2-5 mm in diameter with a smooth surface. The findings are observed from the antrum to the low corpus of the stomach, indicating a diffuse-type nodular gastritis. (B) There were no remarkable changes in nodular elevation on chromoendoscopic findings 1 month after H. pylori eradication, even after applying 0.2% indigo carmine spray. There was also no change in diffuse-type nodular gastritis since the previous examination. 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{"pdf_hash": "144f30f8be53285660e29a9e7d5588c0c685eec4", "fig_key": "Figure8", "fig_uri": "12-Figure8-1.png", "text": "Figure 8 A 73-year-old patient with a neuroendocrine carcinoma of the small intestine and metastatic spread to the liver. 68 Ga-DOTATOC PET/MR shows increased uptake in 2 of the hepatic lesions, corresponding to overexpression of the somatostatin receptor (black arrows; A, PET; B, PET/MR fusion). (C) Diffusion-weighted MRI shows a third suspicious hepatic lesion that was not detected by PET, possibly due to loss of receptor expression (white open arrow). 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{"pdf_hash": "819da65e0188a20ad15125a56ff34cc49653e939", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2: A 3D visualizations of a scoliotic spine clearly reveal the 3D nature of the deformity at hand, i.e. not only a lateral displacement of the spine but also a rotation and deformation of the individual vertebrae. In this case, the CT data has been visualized from the right, the front, the left and the back of a patient.", "width": 1436, "height": 634, "subcaptions": {"a": [64, 65, 66, 45, 46, 47, 48, 49, 50, 51, 52, 53, 63], "b": [64, 65, 66, 45, 46, 47, 48, 49, 50, 51, 55, 56, 63], "c": [64, 65, 66, 45, 46, 47, 48, 49, 50, 51, 58, 59, 63], "d": [64, 65, 66, 45, 46, 47, 48, 49, 50, 51, 61, 62, 63]}, "subfigures": [{"id": "d7875622-c12a-4d27-8a69-3448798c54d4", "label": "a", "points": [[9.7, 4.2], [9.7, 621.2], [359.1, 621.2], [359.1, 4.2]], "color": "yellow"}, {"id": "24e9f6ab-867f-4914-b1e4-1b03cc87ea12", "label": "b", "points": [[365.9, 11], [365.9, 628], [717.5, 628], [717.5, 11]], "color": "cyan"}, {"id": "07ee3973-adee-45a8-a5f7-4b19c8b6c728", "label": "c", "points": [[719.7, 4.2], [719.7, 623.5], [1071.3, 623.5], [1071.3, 4.2]], "color": "magenta"}, {"id": "389da446-9396-4824-aa36-d57918ab417d", "label": "d", "points": [[1085, 11], [1085, 623.5], [1434.3, 623.5], [1434.3, 11]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "3D", "start": 12, "end": 14, "id": 4}, {"text": "visualizations", "start": 15, "end": 29, "id": 5}, {"text": "of", "start": 30, "end": 32, "id": 6}, {"text": "a", "start": 33, "end": 34, "id": 7}, {"text": "scoliotic", "start": 35, "end": 44, "id": 8}, {"text": "spine", "start": 45, "end": 50, "id": 9}, {"text": "clearly", "start": 51, "end": 58, "id": 10}, {"text": "reveal", "start": 59, "end": 65, "id": 11}, {"text": "the", "start": 66, "end": 69, "id": 12}, {"text": "3D", "start": 70, "end": 72, "id": 13}, {"text": "nature", "start": 73, "end": 79, "id": 14}, {"text": "of", "start": 80, "end": 82, "id": 15}, {"text": "the", "start": 83, "end": 86, "id": 16}, {"text": "deformity", "start": 87, "end": 96, "id": 17}, {"text": "at", "start": 97, "end": 99, "id": 18}, {"text": "hand", "start": 100, "end": 104, "id": 19}, {"text": ",", "start": 104, "end": 105, "id": 20}, {"text": "i.e.", "start": 106, "end": 110, "id": 21}, {"text": "not", "start": 111, "end": 114, "id": 22}, {"text": "only", "start": 115, "end": 119, "id": 23}, {"text": "a", "start": 120, "end": 121, "id": 24}, {"text": "lateral", "start": 122, "end": 129, "id": 25}, {"text": "displacement", "start": 130, "end": 142, "id": 26}, {"text": "of", "start": 143, "end": 145, "id": 27}, {"text": "the", "start": 146, "end": 149, "id": 28}, {"text": "spine", "start": 150, "end": 155, "id": 29}, {"text": "but", "start": 156, "end": 159, "id": 30}, {"text": "also", "start": 160, "end": 164, "id": 31}, {"text": "a", "start": 165, "end": 166, "id": 32}, {"text": "rotation", "start": 167, "end": 175, "id": 33}, {"text": "and", "start": 176, "end": 179, "id": 34}, {"text": "deformation", "start": 180, "end": 191, "id": 35}, {"text": "of", "start": 192, "end": 194, "id": 36}, {"text": "the", "start": 195, "end": 198, "id": 37}, {"text": "individual", "start": 199, "end": 209, "id": 38}, {"text": "vertebrae", "start": 210, "end": 219, "id": 39}, {"text": ".", "start": 219, "end": 220, "id": 40}, {"text": "In", "start": 221, "end": 223, "id": 41}, {"text": "this", "start": 224, "end": 228, "id": 42}, {"text": "case", "start": 229, "end": 233, "id": 43}, {"text": ",", "start": 233, "end": 234, "id": 44}, {"text": "the", "start": 235, "end": 238, "id": 45}, {"text": "CT", "start": 239, "end": 241, "id": 46}, {"text": "data", "start": 242, "end": 246, "id": 47}, {"text": "has", "start": 247, "end": 250, "id": 48}, {"text": "been", "start": 251, "end": 255, "id": 49}, {"text": "visualized", "start": 256, "end": 266, "id": 50}, {"text": "from", "start": 267, "end": 271, "id": 51}, {"text": "the", "start": 272, "end": 275, "id": 52}, {"text": "right", "start": 276, "end": 281, "id": 53}, {"text": ",", "start": 281, "end": 282, "id": 54}, {"text": "the", "start": 283, "end": 286, "id": 55}, {"text": "front", "start": 287, "end": 292, "id": 56}, {"text": ",", "start": 292, "end": 293, "id": 57}, {"text": "the", "start": 294, "end": 297, "id": 58}, {"text": "left", "start": 298, "end": 302, "id": 59}, {"text": "and", "start": 303, "end": 306, "id": 60}, {"text": "the", "start": 307, "end": 310, "id": 61}, {"text": "back", "start": 311, "end": 315, "id": 62}, {"text": "of", "start": 316, "end": 318, "id": 63}, {"text": "a", "start": 319, "end": 320, "id": 64}, {"text": "patient", "start": 321, "end": 328, "id": 65}, {"text": ".", "start": 328, "end": 329, "id": 66}]}
{"pdf_hash": "f8a7d96bfd26b153e98a4b95539dbf98e22fc56c", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Figure 6: 76-year-old male with Gallbladder Varices. TECHNIQUE: Enhanced, helical sagittal (A), sagittal magnified (B), coronal (C), and coronal magnified (D) images via Philips iCT 256-slice were obtained of the abdomen and pelvis after the uneventful administration of oral contrast and 100 ml Omnipaque 350 at 4.5 cc/sec, 120 kV and 30 mAs, slice thickness 2.5 mm. 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{"pdf_hash": "365fb2c0443e0f0df5018368bf91bb6bfe69cbba", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 a) Image taken on 20 January 2008 by the Moderate Resolution Imaging Spectroradiometer (MODIS) flying on NASA\u2019s Terra satellite showing numerous plumes of dust blowing off the African coast to Canary Islands (accessible at: http://visibleearth.nasa.gov/ view.php?id=19565). b) Location of CDC-type downdraft miniature suction traps and the location of the livestock in the Gran Canaria farm. 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{"pdf_hash": "7e99f6905e426b05a02f781151d408fc9842d119", "fig_key": "Figure6", "fig_uri": "13-Figure6-1.png", "text": "Fig. 6 MP-RAGE 3T MRI (a, d, f) and corresponding coregistered 11C-PIB slices (b, c, e, g) from two representative patients from Stankoff et al. [83] (d\u2013g correspond to the same patient). c Shows superposition of MRI and PET images. Arrows point to MA plaques, and arrowheads point to gray matter structures, both appearing as a loss of uptake on PET images. Reproduced from Ann Neurol, Stankoff et al. 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{"pdf_hash": "a1d64c57b88b97b73c8200fe14a9a16e34dc8cad", "fig_key": "Figure10", "fig_uri": "17-Figure10-1.png", "text": "Fig. 10. Meshes generated from medical data. (a) MRI scan of a human head. Resolution: 264x264x264. Dihedral angles: [4.33 \u2022 \u2212 157.98 \u2022 ]. \u2248 5.3 million elements. (b) MRI scan of a human torso. Resolution: 208x96x208. Dihedral angles: [5.11 \u2022 \u2212 159.91 \u2022 ]. \u2248 12.6 million elements.", "width": 902, "height": 292, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "fa3ac7ab-bdae-4a3d-9296-af9909170980", "label": "a", "points": [[3.6, 2.9], [3.6, 253.7], [456.7, 253.7], [456.7, 2.9]], "color": "yellow"}, {"id": "ffd75cdc-3de5-4f4c-9785-9b5ce5a79722", "label": "b", "points": [[490.9, 0], [490.9, 250.8], [899.9, 250.8], [899.9, 0]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "10", "start": 5, "end": 7, "id": 2}, {"text": ".", "start": 7, "end": 8, "id": 3}, {"text": "Meshes", "start": 9, "end": 15, "id": 4}, {"text": "generated", "start": 16, "end": 25, "id": 5}, {"text": "from", "start": 26, "end": 30, "id": 6}, {"text": "medical", "start": 31, "end": 38, "id": 7}, {"text": "data", "start": 39, "end": 43, "id": 8}, {"text": ".", "start": 43, "end": 44, "id": 9}, {"text": "(", "start": 45, "end": 46, "id": 10}, {"text": "a", "start": 46, "end": 47, "id": 11}, {"text": ")", "start": 47, "end": 48, "id": 12}, {"text": "MRI", "start": 49, "end": 52, "id": 13}, {"text": "scan", "start": 53, "end": 57, "id": 14}, {"text": "of", "start": 58, "end": 60, "id": 15}, {"text": "a", "start": 61, "end": 62, "id": 16}, {"text": "human", "start": 63, "end": 68, "id": 17}, {"text": "head", "start": 69, "end": 73, "id": 18}, {"text": ".", "start": 73, "end": 74, "id": 19}, {"text": "Resolution", "start": 75, "end": 85, "id": 20}, {"text": ":", "start": 85, "end": 86, "id": 21}, {"text": "264x264x264", "start": 87, "end": 98, "id": 22}, {"text": ".", "start": 98, "end": 99, "id": 23}, {"text": "Dihedral", "start": 100, "end": 108, "id": 24}, {"text": "angles", "start": 109, "end": 115, "id": 25}, {"text": ":", "start": 115, "end": 116, "id": 26}, {"text": "[", "start": 117, "end": 118, "id": 27}, {"text": "4.33", "start": 118, "end": 122, "id": 28}, {"text": "\u2022", "start": 123, "end": 124, "id": 29}, {"text": "\u2212", "start": 125, "end": 126, "id": 30}, {"text": "157.98", "start": 127, "end": 133, "id": 31}, {"text": "\u2022", "start": 134, "end": 135, "id": 32}, {"text": "]", "start": 136, "end": 137, "id": 33}, {"text": ".", "start": 137, "end": 138, "id": 34}, {"text": "\u2248", "start": 139, "end": 140, "id": 35}, {"text": "5.3", "start": 141, "end": 144, "id": 36}, {"text": "million", "start": 145, "end": 152, "id": 37}, {"text": "elements", "start": 153, "end": 161, "id": 38}, {"text": ".", "start": 161, "end": 162, "id": 39}, {"text": "(", "start": 163, "end": 164, "id": 40}, {"text": "b", "start": 164, "end": 165, "id": 41}, {"text": ")", "start": 165, "end": 166, "id": 42}, {"text": "MRI", "start": 167, "end": 170, "id": 43}, {"text": "scan", "start": 171, "end": 175, "id": 44}, {"text": "of", "start": 176, "end": 178, "id": 45}, {"text": "a", "start": 179, "end": 180, "id": 46}, {"text": "human", "start": 181, "end": 186, "id": 47}, {"text": "torso", "start": 187, "end": 192, "id": 48}, {"text": ".", "start": 192, "end": 193, "id": 49}, {"text": "Resolution", "start": 194, "end": 204, "id": 50}, {"text": ":", "start": 204, "end": 205, "id": 51}, {"text": "208x96x208", "start": 206, "end": 216, "id": 52}, {"text": ".", "start": 216, "end": 217, "id": 53}, {"text": "Dihedral", "start": 218, "end": 226, "id": 54}, {"text": "angles", "start": 227, "end": 233, "id": 55}, {"text": ":", "start": 233, "end": 234, "id": 56}, {"text": "[", "start": 235, "end": 236, "id": 57}, {"text": "5.11", "start": 236, "end": 240, "id": 58}, {"text": "\u2022", "start": 241, "end": 242, "id": 59}, {"text": "\u2212", "start": 243, "end": 244, "id": 60}, {"text": "159.91", "start": 245, "end": 251, "id": 61}, {"text": "\u2022", "start": 252, "end": 253, "id": 62}, {"text": "]", "start": 254, "end": 255, "id": 63}, {"text": ".", "start": 255, "end": 256, "id": 64}, {"text": "\u2248", "start": 257, "end": 258, "id": 65}, {"text": "12.6", "start": 259, "end": 263, "id": 66}, {"text": "million", "start": 264, "end": 271, "id": 67}, {"text": "elements", "start": 272, "end": 280, "id": 68}, {"text": ".", "start": 280, "end": 281, "id": 69}]}
{"pdf_hash": "e19d99f894f00ca9909567bf89c8f9530cb67647", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. This picture showed a typical case of relative filling time delay (rFTD): a 71-year-old male patient presenting with left hemiplegia and dysphasia arrived hospital and underwent computer tomography examination 81 minutes after onset. Computer tomography angiography indicated the occluded right internal carotid artery and M1 segment of the right middle cerebral artery. Computer tomography perfusion source imaging (CTP-SI) illustrated that contrast signal (red arrow) firstly appeared in the normal side\u2019s Sylvian fissure in 7:43:46 PM (A), whereas showed up in the occlusion side\u2019s Sylvain fissure in 7:43:56 PM (B), therefore, the time gap of 10 s between bilateral contrast appearances in Sylvian fissure was identified as an rFTD.", "width": 654, "height": 318, "subcaptions": {"a": [62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94], "b": [62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111]}, "subfigures": [{"id": "e2d25b2c-ecd5-462b-af5a-33670a322299", "label": "a", "points": [[1.6, 0.9], [1.6, 289.1], [325, 289.1], [325, 0.9]], "color": "yellow"}, {"id": "c0cc3415-bc04-4473-8b1a-bb969fca9ca5", "label": "b", "points": [[331.2, 1.9], [331.2, 279.8], [651.4, 279.8], [651.4, 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{"pdf_hash": "c826b03a78322d6cccf21e0f53f5e89d32ec57f6", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Characteristic endoscopic views. (A, B) Colonoscopy revealed bluish violet or dark-brownish mucosa in transverse colon (A) and ascending colon, ileocecal region (B). (C) Intestinal stenosis was noted in the hepatic flexure in patients with phlebosclerotic colitis (PC). (D) Colonoscopy showed dark purple appearance, with extensive erosions, ulcerations, and multi-focal nodular surface in a patient with PC.", "width": 1270, "height": 1114, "subcaptions": {"a": [7, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [7, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 28, 29, 30, 31, 32, 33, 34, 35, 36], "c": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "d": [57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83]}, "subfigures": [{"id": "ad7854c3-a362-4768-ba97-f2a2fdd576b8", "label": "a", "points": [[37.1, 30.1], [37.1, 535.7], [645, 535.7], [645, 30.1]], "color": "yellow"}, {"id": "0baa46ee-cc4d-4cc2-803b-c0971c6484a7", "label": "b", "points": [[667.1, 24.1], [667.1, 535.7], [1230.9, 535.7], [1230.9, 24.1]], "color": "cyan"}, {"id": "340ab944-9ae4-411d-b75c-56d08874425f", "label": "c", "points": [[43.1, 549.7], [43.1, 1075.4], [647.1, 1075.4], 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{"pdf_hash": "8d18ed6b746ed2ae9a12e9a58acbb1ee5dd2eb5d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig 1. Endoscopic curettage of a bone cyst of the fibular head of the right knee. The patient is in the lateral position. Magnetic resonance imaging of the illustrated case shows the cystic lesion (arrowhead) of the fibular head. (A) Sagittal view and (B) transverse view. (F, fibula; T, tibia.)", "width": 1064, "height": 716, "subcaptions": {"a": [45, 46, 47, 48, 49], "b": [51, 52, 53, 54, 55]}, "subfigures": [{"id": "d07c57be-5cfb-4a07-a814-211d520ea526", "label": "a", "points": [[0.9, -0.3], [0.9, 707.4], [473.2, 707.4], [473.2, -0.3]], "color": "yellow"}, {"id": "4b772d7a-1c64-4a45-b72b-c3e3ac450746", "label": "b", "points": [[488.4, 3.1], [488.4, 710.7], [1024.5, 710.7], [1024.5, 3.1]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "1", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Endoscopic", "start": 7, "end": 17, "id": 3}, {"text": "curettage", "start": 18, "end": 27, "id": 4}, {"text": "of", "start": 28, "end": 30, "id": 5}, {"text": "a", "start": 31, "end": 32, "id": 6}, {"text": "bone", "start": 33, "end": 37, "id": 7}, {"text": "cyst", "start": 38, "end": 42, "id": 8}, {"text": "of", "start": 43, "end": 45, "id": 9}, {"text": "the", "start": 46, "end": 49, "id": 10}, {"text": "fibular", "start": 50, "end": 57, "id": 11}, {"text": "head", "start": 58, "end": 62, "id": 12}, {"text": "of", "start": 63, "end": 65, "id": 13}, {"text": "the", "start": 66, "end": 69, "id": 14}, {"text": "right", "start": 70, "end": 75, "id": 15}, {"text": "knee", "start": 76, "end": 80, "id": 16}, {"text": ".", "start": 80, "end": 81, "id": 17}, {"text": "The", "start": 82, "end": 85, "id": 18}, {"text": "patient", "start": 86, "end": 93, "id": 19}, {"text": "is", "start": 94, "end": 96, "id": 20}, {"text": "in", "start": 97, "end": 99, "id": 21}, {"text": "the", "start": 100, "end": 103, "id": 22}, {"text": "lateral", "start": 104, "end": 111, "id": 23}, {"text": "position", "start": 112, "end": 120, "id": 24}, {"text": ".", "start": 120, "end": 121, "id": 25}, {"text": "Magnetic", "start": 122, "end": 130, "id": 26}, {"text": "resonance", "start": 131, "end": 140, "id": 27}, {"text": "imaging", "start": 141, "end": 148, "id": 28}, {"text": "of", "start": 149, "end": 151, "id": 29}, {"text": "the", "start": 152, "end": 155, "id": 30}, {"text": "illustrated", "start": 156, "end": 167, "id": 31}, {"text": "case", "start": 168, "end": 172, "id": 32}, {"text": "shows", "start": 173, "end": 178, "id": 33}, {"text": "the", "start": 179, "end": 182, "id": 34}, {"text": "cystic", "start": 183, "end": 189, "id": 35}, {"text": "lesion", "start": 190, "end": 196, "id": 36}, {"text": "(", "start": 197, "end": 198, "id": 37}, {"text": "arrowhead", "start": 198, "end": 207, "id": 38}, {"text": ")", "start": 207, "end": 208, "id": 39}, {"text": "of", "start": 209, "end": 211, "id": 40}, {"text": "the", "start": 212, "end": 215, "id": 41}, {"text": "fibular", "start": 216, "end": 223, "id": 42}, {"text": "head", "start": 224, "end": 228, "id": 43}, {"text": ".", "start": 228, "end": 229, "id": 44}, {"text": "(", "start": 230, "end": 231, "id": 45}, {"text": "A", "start": 231, "end": 232, "id": 46}, {"text": ")", "start": 232, "end": 233, "id": 47}, {"text": "Sagittal", "start": 234, "end": 242, "id": 48}, {"text": "view", "start": 243, "end": 247, "id": 49}, {"text": "and", "start": 248, "end": 251, "id": 50}, {"text": "(", "start": 252, "end": 253, "id": 51}, {"text": "B", "start": 253, "end": 254, "id": 52}, {"text": ")", "start": 254, "end": 255, "id": 53}, {"text": "transverse", "start": 256, "end": 266, "id": 54}, {"text": "view", "start": 267, "end": 271, "id": 55}, {"text": ".", "start": 271, "end": 272, "id": 56}, {"text": "(", "start": 273, "end": 274, "id": 57}, {"text": "F", "start": 274, "end": 275, "id": 58}, {"text": ",", "start": 275, "end": 276, "id": 59}, {"text": "fibula", "start": 277, "end": 283, "id": 60}, {"text": ";", "start": 283, "end": 284, "id": 61}, {"text": "T", "start": 285, "end": 286, "id": 62}, {"text": ",", "start": 286, "end": 287, "id": 63}, {"text": "tibia", "start": 288, "end": 293, "id": 64}, {"text": ".", "start": 293, "end": 294, "id": 65}, {"text": ")", "start": 294, "end": 295, "id": 66}]}
{"pdf_hash": "fda5baede8a19d3fafeb5a246d4816f47d4ff628", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "FIGURE 6: Intravoxel incoherent motion (IVIM) diffusion-weighted imaging in glioblastoma. MRI of a 64-year-old female with a right frontal glioblastoma as shown on pre-(a) and postcontrast T 1 -weighted imaging (b). DSC demonstrated elevated perfusion at location of contrast enhancement (c) and diffusion-weighted imaging showed decreased ADC laterally due to increased cellularity and elevated ADC in the necrotic core (d). IVIM imaging uses a biexponential model of signal decay (e). The diffusion signal is demonstrated in white for different b-values. With IVIM this signal decay can be divided into the flow-related pseudodiffusion (red dotted line) and the true diffusion (blue dotted line). The perfusion fraction (f) results from the signal difference between pseudodiffusion and true diffusion. The perfusion fraction demonstrated similar results to DSC-rCBV (c). A pseudodiffusion map is also shown (g). IVIM-derived true diffusion maps (h) are comparable to ADC with elevated values in the necrotic core. 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{"pdf_hash": "01598346777c5615c4ab5f74836c419bb1e4315a", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Patient No. 10 had a squamous cell carcinoma in the left hard palate, with tumor recurrence over the left palatine tonsil and invasion into the masseter muscle (A, black arrow). Complete response occurred after 6 months of treatment with pembrolizumab (B, black arrow). Patient No. 12 had a papillary thyroid cancer with surrounding invasion, and received palliative resection in 2014. Tumor recurrence (C, white arrow) in 2015 and a biopsy revealed squamous cell carcinoma, probably originating from the thyroid. 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{"pdf_hash": "f48dc1445b787a422aa28bd6dabda7e24caed380", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Sagittal (A) and axial (B, C) T2-weighted MRI showing disc extrusion (white arrows) at the L4-5.", "width": 1008, "height": 728, "subcaptions": {"a": [4, 5, 6, 7, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "6e60b9aa-7905-4418-945a-84a99b7f115b", "label": "a", "points": [[3.2, 0], [3.2, 727.8], [619.5, 727.8], [619.5, 0]], "color": "yellow"}, {"id": "6a946634-7ffb-4b76-85c8-7f8cb8f8154b", "label": "b", "points": [[974.6, 3.2], [974.6, 366.3], [625.8, 366.3], [625.8, 3.2]], "color": "cyan"}, {"id": "7294f82e-dbf2-48be-b934-28229073c5e0", "label": "b", "points": [[979.4, 371], [979.4, 724.6], [624.2, 724.6], [624.2, 371]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Sagittal", "start": 8, "end": 16, "id": 4}, {"text": "(", "start": 17, "end": 18, "id": 5}, {"text": "A", "start": 18, "end": 19, "id": 6}, {"text": ")", "start": 19, "end": 20, "id": 7}, {"text": "and", "start": 21, "end": 24, "id": 8}, {"text": "axial", "start": 25, "end": 30, "id": 9}, {"text": "(", "start": 31, "end": 32, "id": 10}, {"text": "B", "start": 32, "end": 33, "id": 11}, {"text": ",", "start": 33, "end": 34, "id": 12}, {"text": "C", "start": 35, "end": 36, "id": 13}, {"text": ")", "start": 36, "end": 37, "id": 14}, {"text": "T2-weighted", "start": 38, "end": 49, "id": 15}, {"text": "MRI", "start": 50, "end": 53, "id": 16}, {"text": "showing", "start": 54, "end": 61, "id": 17}, {"text": "disc", "start": 62, "end": 66, "id": 18}, {"text": "extrusion", "start": 67, "end": 76, "id": 19}, {"text": "(", "start": 77, "end": 78, "id": 20}, {"text": "white", "start": 78, "end": 83, "id": 21}, {"text": "arrows", "start": 84, "end": 90, "id": 22}, {"text": ")", "start": 90, "end": 91, "id": 23}, {"text": "at", "start": 92, "end": 94, "id": 24}, {"text": "the", "start": 95, "end": 98, "id": 25}, {"text": "L4", "start": 99, "end": 101, "id": 26}, {"text": "-", "start": 101, "end": 102, "id": 27}, {"text": "5", "start": 102, "end": 103, "id": 28}, {"text": ".", "start": 103, "end": 104, "id": 29}]}
{"pdf_hash": "7af8f97130e7f4c8e4ecc977e894e29db1104765", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Subsurface near-field Raman imaging of carbon nanotubes overcoated with an SiO 2 Fischer pattern (\u223c10 nm thickness). (a) Larger scale topographic (AFM) image of the sample revealing nanotubes that are only partially covered. (b) Topographic image of a partially over coated carbon nanotube. (c) Simultaneously acquired near-field Raman image. The contrast in the image reflects the local intensity of the Raman G band (1590 cm -1 ). (d) Cross sections taken along the lines indicated in (c). The far-field background has been subtracted. 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{"pdf_hash": "2d061dd13c8a22f7cd9e1bd01949b9082da5e900", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig 1. Surface representations of the Str. enolase and human plasminogen crystal structures. A. The homo-octamer of Str. enolase (green) presented in front and side view. The red color represents the carboxy-terminal amino acid residues from 428 to 433 at the dimer-dimer interface where the truncations were made; the salmon color represents the amino acid residues 252 and 255. The last two residues, 434, 435, are not visible in the X-ray structure nor are the residues of the hexa-his tag. The dimensions of Str. enolase are 15 nm x 5 nm. B. Human plasminogen with the five kringle domains and the preproteolytic domain shown in different colors. Its dimensions are 10 nm x 8.5 nm x 5 nm. The crystal structures were taken from the PDB (Str. enolase 3ZLH) [10] and Plasminogen (4DUU) [8]. 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{"pdf_hash": "66a5738baa6dcb40199d555f07bd8af3bc4808c5", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Outline of electrode localization and intersubject mapping procedure. (A) The preoperative MRI is coregistered with the postoperative CT volume. The lower panel shows the maximal-intensity projection of the CT volume in the sagittal dimension, which shows all the electrodes in a sagittal plane. (B) Due to the parenchymal shift from the implant procedure, some electrodes initially appear as though buried in the gray matter. To correct for this, each electrode coordinate is projected first to a smoothed pial surface (effectively a dural surface) and subsequently back to the pial surface. (C) 2D registration with the Freesurfer average brain. An inflated spherical surface is computed from the individual's pial surface and aligned with that of the Freesurfer average. 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{"pdf_hash": "743ecde1fc4c2eff62d2ca79805757b756572c11", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Preoperative CT and 3D reconstruction images. A: A 3D reconstructed CT showing the lesion in the right occipital region with a slight bulge in the skin (white circle). 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{"pdf_hash": "0379a89e1b2d835e5cd184be424d9859b6d288b7", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4: Cadaver photos illustrating the authors\u2019 technique keyhole. (a) Bone exposure for a left\u2011side standard MPT approach; (b) keyhole enlargement by drilling the extracranial surface of sphenoid wing; (c) drilling sphenoid ridge before performing the craniotomy; (d) craniotomy. CS = coronal suture; SS = squamosal suture; SFS = sphenofrontal suture; SPS = sphenoparietal suture; SSS = sphenosquamosal suture; SZS = sphenozygomatic suture; MT = marginal tubercle, MMA = middle meningeal artery", "width": 674, "height": 698, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "d": [49, 50, 51, 52, 53]}, "subfigures": [{"id": "3a74f5af-e092-42d8-a832-73de3637d070", "label": "a", "points": [[1.6, 0], [1.6, 339.7], [338.1, 339.7], [338.1, 0]], "color": "yellow"}, {"id": "7d2fc67a-f45f-4a14-8017-70453f0ca9cf", "label": "b", "points": [[341.3, 3.2], [341.3, 335.4], [671.3, 335.4], [671.3, 3.2]], "color": "cyan"}, {"id": "70c81630-af95-4a49-90e5-35c10af370db", "label": "d", "points": [[0.5, 348.2], [0.5, 681.5], [333.8, 681.5], [333.8, 348.2]], "color": "magenta"}, {"id": "2dfd4cfe-baff-46cf-b713-ac6eb9d27223", "label": "d", "points": [[347.7, 342.9], [347.7, 681.5], [668.2, 681.5], [668.2, 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{"pdf_hash": "2e8591302d5ed1da2ec3c50ca6a2a944c1fbb407", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Preoperative magnetic resonance imaging. Left/middle: T1-weighted axial gadolinium-enhanced image showing an enhancing tumor of the right frontal lobe. Right: T2-weighted image showing the same lesion as in the previous images, with notable edema.", "width": 690, "height": 246, "subcaptions": {"a": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "294325a1-4aff-41e1-99b6-3b58bd227c1f", "label": "a", "points": [[7.8, 6.9], [7.8, 209.7], [231.3, 209.7], [231.3, 6.9]], "color": "yellow"}, {"id": "029202aa-03ea-4e93-a9ae-e98b3991d047", "label": "a", "points": [[236.7, 11.3], [236.7, 211.8], [462.4, 211.8], [462.4, 11.3]], "color": "cyan"}, {"id": "1feeca1c-baf5-44ee-ad68-f2aea57cf7fb", "label": "b", "points": [[466.7, 9.1], [466.7, 205.3], [681.5, 205.3], [681.5, 9.1]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Preoperative", "start": 10, "end": 22, "id": 3}, {"text": "magnetic", "start": 23, "end": 31, "id": 4}, {"text": "resonance", "start": 32, "end": 41, "id": 5}, {"text": "imaging", "start": 42, "end": 49, "id": 6}, {"text": ".", "start": 49, "end": 50, "id": 7}, {"text": "Left", "start": 51, "end": 55, "id": 8}, {"text": "/", "start": 55, "end": 56, "id": 9}, {"text": "middle", "start": 56, "end": 62, "id": 10}, {"text": ":", "start": 62, "end": 63, "id": 11}, {"text": "T1-weighted", "start": 64, "end": 75, "id": 12}, {"text": "axial", "start": 76, "end": 81, "id": 13}, {"text": "gadolinium", "start": 82, "end": 92, "id": 14}, {"text": "-", "start": 92, "end": 93, "id": 15}, {"text": "enhanced", "start": 93, "end": 101, "id": 16}, {"text": "image", "start": 102, "end": 107, "id": 17}, {"text": "showing", "start": 108, "end": 115, "id": 18}, {"text": "an", "start": 116, "end": 118, "id": 19}, {"text": "enhancing", "start": 119, "end": 128, "id": 20}, {"text": "tumor", "start": 129, "end": 134, "id": 21}, {"text": "of", "start": 135, "end": 137, "id": 22}, {"text": "the", "start": 138, "end": 141, "id": 23}, {"text": "right", "start": 142, "end": 147, "id": 24}, {"text": "frontal", "start": 148, "end": 155, "id": 25}, {"text": "lobe", "start": 156, "end": 160, "id": 26}, {"text": ".", "start": 160, "end": 161, "id": 27}, {"text": "Right", "start": 162, "end": 167, "id": 28}, {"text": ":", "start": 167, "end": 168, "id": 29}, {"text": "T2-weighted", "start": 169, "end": 180, "id": 30}, {"text": "image", "start": 181, "end": 186, "id": 31}, {"text": "showing", "start": 187, "end": 194, "id": 32}, {"text": "the", "start": 195, "end": 198, "id": 33}, {"text": "same", "start": 199, "end": 203, "id": 34}, {"text": "lesion", "start": 204, "end": 210, "id": 35}, {"text": "as", "start": 211, "end": 213, "id": 36}, {"text": "in", "start": 214, "end": 216, "id": 37}, {"text": "the", "start": 217, "end": 220, "id": 38}, {"text": "previous", "start": 221, "end": 229, "id": 39}, {"text": "images", "start": 230, "end": 236, "id": 40}, {"text": ",", "start": 236, "end": 237, "id": 41}, {"text": "with", "start": 238, "end": 242, "id": 42}, {"text": "notable", "start": 243, "end": 250, "id": 43}, {"text": "edema", "start": 251, "end": 256, "id": 44}, {"text": ".", "start": 256, "end": 257, "id": 45}]}
{"pdf_hash": "7e6715c52eeebdacc95615a84ce00306c7aa7dcf", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 Imaging, surgical and pathogenic findings in the patient. (a) A space-occupying lesion (red arrow) was observed in the left atrium measured 60 \u00d7 54 mm by cardiac ultrasonography. (b) Abdominal CT scan showed extensive intrahepatic bile duct dilatation (red arrow). (c) The round cardiac mass (white arrow) in the left atrium was exposed in the surgery, which was an endocardial hematoma close to the posterior mitral valve. (d) The egg of C. sinensis (red arrow) was firstly identified in the stool samples, and later a smaller egg (black arrow) consistent with that of heterophyid trematodes was distinguished from C. sinensis. 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{"pdf_hash": "d6165ce5c68f4fa86892d5cb1007d70df60272a8", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Fig. 6 a CT imaging, coronal view, post-contrast, demonstrating an expansile soft tissue mass centered within the left masseteric space with destruction of the posterior alveolar bone from case #3, b 3-D reconstruction of the same patient highlighting the bulging of the left masseteric muscle due to tumor mass", "width": 996, "height": 534, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "b1700cd5-053f-4890-ac08-75f64efeb842", "label": "a", "points": [[0.8, 1.6], [0.8, 531.8], [449.2, 531.8], [449.2, 1.6]], "color": "yellow"}, {"id": "767aa8f8-f808-4587-95fa-ea026db0ba74", "label": "b", "points": [[466.5, 1.6], [466.5, 528.7], [990.5, 528.7], [990.5, 1.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "6", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "CT", "start": 9, "end": 11, "id": 4}, {"text": "imaging", "start": 12, "end": 19, "id": 5}, {"text": ",", "start": 19, "end": 20, "id": 6}, {"text": "coronal", "start": 21, "end": 28, "id": 7}, {"text": "view", "start": 29, "end": 33, "id": 8}, {"text": ",", "start": 33, "end": 34, "id": 9}, {"text": "post", "start": 35, "end": 39, "id": 10}, {"text": "-", "start": 39, "end": 40, "id": 11}, {"text": "contrast", "start": 40, "end": 48, "id": 12}, {"text": ",", "start": 48, "end": 49, "id": 13}, {"text": "demonstrating", "start": 50, "end": 63, "id": 14}, {"text": "an", "start": 64, "end": 66, "id": 15}, {"text": "expansile", "start": 67, "end": 76, "id": 16}, {"text": "soft", "start": 77, "end": 81, "id": 17}, {"text": "tissue", "start": 82, "end": 88, "id": 18}, {"text": "mass", "start": 89, "end": 93, "id": 19}, {"text": "centered", "start": 94, "end": 102, "id": 20}, {"text": "within", "start": 103, "end": 109, "id": 21}, {"text": "the", "start": 110, "end": 113, "id": 22}, {"text": "left", "start": 114, "end": 118, "id": 23}, {"text": "masseteric", "start": 119, "end": 129, "id": 24}, {"text": "space", "start": 130, "end": 135, "id": 25}, {"text": "with", "start": 136, "end": 140, "id": 26}, {"text": "destruction", "start": 141, "end": 152, "id": 27}, {"text": "of", "start": 153, "end": 155, "id": 28}, {"text": "the", "start": 156, "end": 159, "id": 29}, {"text": "posterior", "start": 160, "end": 169, "id": 30}, {"text": "alveolar", "start": 170, "end": 178, "id": 31}, {"text": "bone", "start": 179, "end": 183, "id": 32}, {"text": "from", "start": 184, "end": 188, "id": 33}, {"text": "case", "start": 189, "end": 193, "id": 34}, {"text": "#", "start": 194, "end": 195, "id": 35}, {"text": "3", "start": 195, "end": 196, "id": 36}, {"text": ",", "start": 196, "end": 197, "id": 37}, {"text": "b", "start": 198, "end": 199, "id": 38}, {"text": "3-D", "start": 200, "end": 203, "id": 39}, {"text": "reconstruction", "start": 204, "end": 218, "id": 40}, {"text": "of", "start": 219, "end": 221, "id": 41}, {"text": "the", "start": 222, "end": 225, "id": 42}, {"text": "same", "start": 226, "end": 230, "id": 43}, {"text": "patient", "start": 231, "end": 238, "id": 44}, {"text": "highlighting", "start": 239, "end": 251, "id": 45}, {"text": "the", "start": 252, "end": 255, "id": 46}, {"text": "bulging", "start": 256, "end": 263, "id": 47}, {"text": "of", "start": 264, "end": 266, "id": 48}, {"text": "the", "start": 267, "end": 270, "id": 49}, {"text": "left", "start": 271, "end": 275, "id": 50}, {"text": "masseteric", "start": 276, "end": 286, "id": 51}, {"text": "muscle", "start": 287, "end": 293, "id": 52}, {"text": "due", "start": 294, "end": 297, "id": 53}, {"text": "to", "start": 298, "end": 300, "id": 54}, {"text": "tumor", "start": 301, "end": 306, "id": 55}, {"text": "mass", "start": 307, "end": 311, "id": 56}]}
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{"pdf_hash": "40786735d148b33940ad295d5cbc2d38910c8059", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Prolonged rigid paralysis led to vertebral wedging in the thoracic region. (A) Representative sagittal 3D view of thoracic spine segment (T4-T7) of control and rigidly paralyzed specimens. Yellow lines in each case show how the vertebral body angle measurements were created. (B) Schematic view of thoracic spinal segments in (A) illustrating the differences in vertebral wedging and separation of vertebrae. (C) Individual spines from five distinct chicks (i-v) paralyzed rigidly from E3-E9 showing evidence of vertebral wedging in the thoracic region (gray boxes). In regions of extreme curvature (indicated by arrow heads), separation at the anterior vertebral body joints occurs while the posterior spinous process joints remain intact. 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{"pdf_hash": "df51262896c2ebfc78f22775bd6662742589bc86", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 The arrangement of zebrin II-immunoreactive parasagittal stripes in the cerebella of littermate wild type, heterozygous and homozygous dreher mutant mice, shown in wholemount. a The posterior lobe vermis of a ?/? cerebellum immunoperoxidase-stained for anti-zebrin II. Zebrin II is expressed by a series of parasagittal stripes of Purkinje cells in the vermis and hemispheres of the posterior cerebellum. b The posterior lobe vermis of a cerebellum from a heterozygous animal immunoperoxidase-stained for anti-zebrin II. The expression of zebrin II is normal in the vermis and the hemispheres. c The posterior lobe vermis of a cerebellum from a homozygous dreher animal immunoperoxidase-stained for anti-zebrin II. The posterior lobe vermis is almost completely absent from the midline and is replaced by an ectopic mass of tissue. The hemispheric lobules are irregularly shaped but relatively correctly positioned. Zebrin II is expressed in parasagittal stripes in the hemispheres. Note that despite its small size, the vermis of lobule V is positioned normally. The vermis of the rostral aspect of lobule VI is present but deflected laterally and only partially fused at the midline. As in control and heterozygous cerebella, the expression of zebrin II in lobules V\u2013VI in the homozygous dreher cerebellum reflects the AZ to CZ transition. Roman numerals indicate cerebellar lobules. Scale bar 1 mm in c (also applies to a, b)", "width": 646, "height": 1050, "subcaptions": {"a": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73], "b": [74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108], "c": [109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 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{"pdf_hash": "52175cbfa02501c5325e10f386d1fae111309090", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "FIGURE 1. Osteoblastic osteosarcoma in a patient with primary mandibular osteosarcoma (Case 9). (A) Computed tomography scan shows a well-circumscribed, heavily mineralized tumor involving the body of the mandible, which was resected with negative margins. (B) Histologically, it had extensive malignant osteoid production. 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{"pdf_hash": "cf9bc27e10d372c97e260e3d013ed7ddf13fe926", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Figure 6. Anterior segment optical coherence tomography images of the same central cornea, followed over 4 years in biosynthetic and human donor implanted corneas. Left column: Biosynthetic implant in a 30 year old female appears stable over time (slight differences are due to slightly different location of sections). Center column: Human donor cornea in a 52 year old male exhibits wound compression due to the sutures, posterior donorrecipient edges mismatch, posterior graft protrusion (arrowhead), and stromal compression lines (arrows) that resolve after suture removal at 1 year. Right column: Appearance of four healthy corneas aged 16\u201364 years. 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{"pdf_hash": "d548020b6ce4a41ef05bb4054236851dd6a6c058", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Fig. 6. Coronal sections of the goat ME with CRF-IR (A), AVP-IR (B) and OXY-IR (C). Note that dense CRF-IR terminals are found in the external parisade zone and some CRF-IR fibers are in the internal parisade zone. In contrast, AVP-IR (B) and OXY-IR (C) terminals are found in the external parisade zone and dense IR-fibers are in the internal parisade zone. 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{"pdf_hash": "6f9c1860e1b59a1d709a157afc7125f027281743", "fig_key": "Figure11", "fig_uri": "15-Figure11-1.png", "text": "Figure 11. Intracardiac echocardiogram (ICE) image of a released Amplatzer PFO Occluder (top) (*) and Gore Cardioform Septal Occluder (bottom) (*). Agitated saline is seen in the right atrium (RA), but not in the left atrium (LA), confirming the absence of right to left shunt after device deployment.", "width": 674, "height": 846, "subcaptions": {"a": [32, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [32, 3, 4, 5, 6, 7, 8, 9, 10, 11, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "c95ca056-ce32-49a2-a29e-1b5592ad3dbc", "label": "a", "points": [[20.2, 18.1], [20.2, 405.7], [639.9, 405.7], [639.9, 18.1]], "color": "yellow"}, {"id": "798abc4e-77e7-453d-8e65-586e16b07ee7", "label": "b", "points": [[24.5, 420.6], [24.5, 814.6], [644.2, 814.6], [644.2, 420.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "11", "start": 7, "end": 9, "id": 1}, {"text": ".", "start": 9, "end": 10, "id": 2}, {"text": "Intracardiac", "start": 11, "end": 23, "id": 3}, {"text": "echocardiogram", "start": 24, "end": 38, "id": 4}, {"text": "(", "start": 39, "end": 40, "id": 5}, {"text": "ICE", "start": 40, "end": 43, "id": 6}, {"text": ")", "start": 43, "end": 44, "id": 7}, {"text": "image", "start": 45, "end": 50, "id": 8}, {"text": "of", "start": 51, "end": 53, "id": 9}, {"text": "a", "start": 54, "end": 55, "id": 10}, {"text": "released", "start": 56, "end": 64, "id": 11}, {"text": "Amplatzer", "start": 65, "end": 74, "id": 12}, {"text": "PFO", "start": 75, "end": 78, "id": 13}, {"text": "Occluder", "start": 79, "end": 87, "id": 14}, {"text": "(", "start": 88, "end": 89, "id": 15}, {"text": "top", "start": 89, "end": 92, "id": 16}, {"text": ")", "start": 92, "end": 93, "id": 17}, {"text": "(", "start": 94, "end": 95, "id": 18}, {"text": "*", "start": 95, "end": 96, "id": 19}, {"text": ")", "start": 96, "end": 97, "id": 20}, {"text": "and", "start": 98, "end": 101, "id": 21}, {"text": "Gore", "start": 102, "end": 106, "id": 22}, {"text": "Cardioform", "start": 107, "end": 117, "id": 23}, {"text": "Septal", "start": 118, "end": 124, "id": 24}, {"text": "Occluder", "start": 125, "end": 133, "id": 25}, {"text": "(", "start": 134, "end": 135, "id": 26}, {"text": "bottom", "start": 135, "end": 141, "id": 27}, {"text": ")", "start": 141, "end": 142, "id": 28}, {"text": "(", "start": 143, "end": 144, "id": 29}, {"text": "*", "start": 144, "end": 145, "id": 30}, {"text": ")", "start": 145, "end": 146, "id": 31}, {"text": ".", "start": 146, "end": 147, "id": 32}, {"text": "Agitated", "start": 148, "end": 156, "id": 33}, {"text": "saline", "start": 157, "end": 163, "id": 34}, {"text": "is", "start": 164, "end": 166, "id": 35}, {"text": "seen", "start": 167, "end": 171, "id": 36}, {"text": "in", "start": 172, "end": 174, "id": 37}, {"text": "the", "start": 175, "end": 178, "id": 38}, {"text": "right", "start": 179, "end": 184, "id": 39}, {"text": "atrium", "start": 185, "end": 191, "id": 40}, {"text": "(", "start": 192, "end": 193, "id": 41}, {"text": "RA", "start": 193, "end": 195, "id": 42}, {"text": ")", "start": 195, "end": 196, "id": 43}, {"text": ",", "start": 196, "end": 197, "id": 44}, {"text": "but", "start": 198, "end": 201, "id": 45}, {"text": "not", "start": 202, "end": 205, "id": 46}, {"text": "in", "start": 206, "end": 208, "id": 47}, {"text": "the", "start": 209, "end": 212, "id": 48}, {"text": "left", "start": 213, "end": 217, "id": 49}, {"text": "atrium", "start": 218, "end": 224, "id": 50}, {"text": "(", "start": 225, "end": 226, "id": 51}, {"text": "LA", "start": 226, "end": 228, "id": 52}, {"text": ")", "start": 228, "end": 229, "id": 53}, {"text": ",", "start": 229, "end": 230, "id": 54}, {"text": "confirming", "start": 231, "end": 241, "id": 55}, {"text": "the", "start": 242, "end": 245, "id": 56}, {"text": "absence", "start": 246, "end": 253, "id": 57}, {"text": "of", "start": 254, "end": 256, "id": 58}, {"text": "right", "start": 257, "end": 262, "id": 59}, {"text": "to", "start": 263, "end": 265, "id": 60}, {"text": "left", "start": 266, "end": 270, "id": 61}, {"text": "shunt", "start": 271, "end": 276, "id": 62}, {"text": "after", "start": 277, "end": 282, "id": 63}, {"text": "device", "start": 283, "end": 289, "id": 64}, {"text": "deployment", "start": 290, "end": 300, "id": 65}, {"text": ".", "start": 300, "end": 301, "id": 66}]}
{"pdf_hash": "e5e5646c712749500f1fb72627cae0054c679367", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. A : Sonographical images of spinal cord in axial planes in a term infant. White arrows pointed to conus medullaris. B : Sonographical images of spinal cord in Sagittal planes in a term infant.", "width": 658, "height": 258, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40]}, "subfigures": [{"id": "9ac93497-6cd6-4891-aaa2-486a4397e00b", "label": "a", "points": [[0.2, 0.3], [0.2, 230.1], [325.5, 230.1], [325.5, 0.3]], "color": "yellow"}, {"id": "afea8214-d346-476f-b867-3e7092b2ad03", "label": "b", "points": [[331.8, 2.4], [331.8, 218.6], [654, 218.6], [654, 2.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": ":", "start": 10, "end": 11, "id": 5}, {"text": "Sonographical", "start": 12, "end": 25, "id": 6}, {"text": "images", "start": 26, "end": 32, "id": 7}, {"text": "of", "start": 33, "end": 35, "id": 8}, {"text": "spinal", "start": 36, "end": 42, "id": 9}, {"text": "cord", "start": 43, "end": 47, "id": 10}, {"text": "in", "start": 48, "end": 50, "id": 11}, {"text": "axial", "start": 51, "end": 56, "id": 12}, {"text": "planes", "start": 57, "end": 63, "id": 13}, {"text": "in", "start": 64, "end": 66, "id": 14}, {"text": "a", "start": 67, "end": 68, "id": 15}, {"text": "term", "start": 69, "end": 73, "id": 16}, {"text": "infant", "start": 74, "end": 80, "id": 17}, {"text": ".", "start": 80, "end": 81, "id": 18}, {"text": "White", "start": 82, "end": 87, "id": 19}, {"text": "arrows", "start": 88, "end": 94, "id": 20}, {"text": "pointed", "start": 95, "end": 102, "id": 21}, {"text": "to", "start": 103, "end": 105, "id": 22}, {"text": "conus", "start": 106, "end": 111, "id": 23}, {"text": "medullaris", "start": 112, "end": 122, "id": 24}, {"text": ".", "start": 122, "end": 123, "id": 25}, {"text": "B", "start": 124, "end": 125, "id": 26}, {"text": ":", "start": 126, "end": 127, "id": 27}, {"text": "Sonographical", "start": 128, "end": 141, "id": 28}, {"text": "images", "start": 142, "end": 148, "id": 29}, {"text": "of", "start": 149, "end": 151, "id": 30}, {"text": "spinal", "start": 152, "end": 158, "id": 31}, {"text": "cord", "start": 159, "end": 163, "id": 32}, {"text": "in", "start": 164, "end": 166, "id": 33}, {"text": "Sagittal", "start": 167, "end": 175, "id": 34}, {"text": "planes", "start": 176, "end": 182, "id": 35}, {"text": "in", "start": 183, "end": 185, "id": 36}, {"text": "a", "start": 186, "end": 187, "id": 37}, {"text": "term", "start": 188, "end": 192, "id": 38}, {"text": "infant", "start": 193, "end": 199, "id": 39}, {"text": ".", "start": 199, "end": 200, "id": 40}]}
{"pdf_hash": "f273d1bba525a5d25e896875f63a80e76f0e875f", "fig_key": "Figure9", "fig_uri": "15-Figure9-1.png", "text": "FIGURE 9. Conventional thin section of a human alveolar macrophage from a heavy cigarette smoker (same specimen as Fig. 8) is shown in A. The cells were fixed with glutaraldehyde only; consequently, only inherent tissue and foreign particle contrast is seen. A portion of a single alveolar macrophage shows numerous particles of aluminum silicates and other xenobiotics in lysosomes (double arrows), and two lobes of the nucleus (N) are discerned. The nuclear envelope (single arrows) and associated heterochromatin are intact. The same field is illustrated in B after considerable sputtering from the secondary ion beam. There is marked loss of heterochromatin associated with the nuclear envelope (arrows). Nuclei (N) therefore stand out in bold relief. A suggestion of preferential lysosomal etching is also seen (asterisks). Some particles (double arrows) appear relatively resistant to etching. Iransmission electron microscopy. Magnification: (A) x 12,500; (B) x6,300.", "width": 998, "height": 1572, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94], "b": [95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165]}, "subfigures": [{"id": "370cfbb0-8c0f-4703-bfb8-78259bd9753a", "label": "a", "points": [[0, 3.2], [0, 769.4], [991.7, 769.4], [991.7, 3.2]], "color": "yellow"}, {"id": 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{"pdf_hash": "c9deda16632f3c918ba1802124f18a10c76a27ea", "fig_key": "Figure5", "fig_uri": "8-Figure5-1.png", "text": "Fig. 5. Late floral and gynoecial differentiation of Berberidopsis beckleri. (A) Longitudinal section of young flower. Note the progressive change in size of bracts and tepals. (B) Partially sectioned flower showing the massive protruding intercarpellary ridges in the ovary. (C) Flower with partly dissected ovary showing early ovule differentiation on the intercarpellary protrusions. (D) Transverse section of young ovary showing five parietal placental ridges with two series of ovules each. (E) Longitudinal section of ovary showing three of the five placentas with ovules. (F) Transverse section of nearly mature ovary with four placental ridges and anatropous ovules. (G) Adaxial view of the upper part of immature anther with long apical connective. (H) View of five-lobed stigma at anthesis completely covered with exudate. (I) Lateral view of lobed, extrastaminal disc nectary; stamens removed. Ri, intercarpellary protuberance; Pl, placenta. 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{"pdf_hash": "2dc585c1021c2d1e32a512080863d62195e71ba6", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 a CT scan documenting right pararenal hypervascular metastatsis (diameter 34 mm). b CT scan performed after cyberknife. The lesion, substantially stable in size, became completely hypodense", "width": 1250, "height": 466, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34]}, "subfigures": [{"id": "93448de4-76b5-4c3d-ba23-6b524d19d2f9", "label": "a", "points": [[42.5, 18.6], [42.5, 435.2], [617.2, 435.2], [617.2, 18.6]], "color": "yellow"}, {"id": "bb1f77d8-0869-4d7b-9061-431f6d41e257", "label": "b", "points": [[640.8, 16.6], [640.8, 433.3], [1205.6, 433.3], [1205.6, 16.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "CT", "start": 9, "end": 11, "id": 4}, {"text": "scan", "start": 12, "end": 16, "id": 5}, {"text": "documenting", "start": 17, "end": 28, "id": 6}, {"text": "right", "start": 29, "end": 34, "id": 7}, {"text": "pararenal", "start": 35, "end": 44, "id": 8}, {"text": "hypervascular", "start": 45, "end": 58, "id": 9}, {"text": "metastatsis", "start": 59, "end": 70, "id": 10}, {"text": "(", "start": 71, "end": 72, "id": 11}, {"text": "diameter", "start": 72, "end": 80, "id": 12}, {"text": "34", "start": 81, "end": 83, "id": 13}, {"text": "mm", "start": 84, "end": 86, "id": 14}, {"text": ")", "start": 86, "end": 87, "id": 15}, {"text": ".", "start": 87, "end": 88, "id": 16}, {"text": "b", "start": 89, "end": 90, "id": 17}, {"text": "CT", "start": 91, "end": 93, "id": 18}, {"text": "scan", "start": 94, "end": 98, "id": 19}, {"text": "performed", "start": 99, "end": 108, "id": 20}, {"text": "after", "start": 109, "end": 114, "id": 21}, {"text": "cyberknife", "start": 115, "end": 125, "id": 22}, {"text": ".", "start": 125, "end": 126, "id": 23}, {"text": "The", "start": 127, "end": 130, "id": 24}, {"text": "lesion", "start": 131, "end": 137, "id": 25}, {"text": ",", "start": 137, "end": 138, "id": 26}, {"text": "substantially", "start": 139, "end": 152, "id": 27}, {"text": "stable", "start": 153, "end": 159, "id": 28}, {"text": "in", "start": 160, "end": 162, "id": 29}, {"text": "size", "start": 163, "end": 167, "id": 30}, {"text": ",", "start": 167, "end": 168, "id": 31}, {"text": "became", "start": 169, "end": 175, "id": 32}, {"text": "completely", "start": 176, "end": 186, "id": 33}, {"text": "hypodense", "start": 187, "end": 196, "id": 34}]}
{"pdf_hash": "58933331469f5ebd662679f6a109d9f3910b2cd2", "fig_key": "Figure20", "fig_uri": "15-Figure20-1.png", "text": "Figure 20. Multicystic mesothelioma in an asymptomatic 60-year-old woman with a palpable mass found at pelvic examination. (a) Coronal T2-weighted MR image shows a multiseptated cystic mass (arrows) along the peritoneal surfaces of the uterus and broad ligaments. (b) Sagittal gadolinium-enhanced MR image reveals enhancement of the septa (arrow) and extension of the mass into the cul-de-sac.", "width": 1066, "height": 542, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "b": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76]}, "subfigures": [{"id": "2cba45f8-78a1-4468-88bc-ead73545915d", "label": "a", "points": [[7, 2.2], [7, 475.5], [532.5, 475.5], [532.5, 2.2]], "color": "yellow"}, {"id": "24b115cb-eceb-4641-8542-193d62e19d0f", "label": "b", "points": [[545.9, 2.2], [545.9, 478.8], [1059.6, 478.8], [1059.6, 2.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "20", "start": 7, "end": 9, "id": 1}, {"text": ".", "start": 9, "end": 10, "id": 2}, {"text": "Multicystic", "start": 11, "end": 22, "id": 3}, {"text": "mesothelioma", "start": 23, "end": 35, "id": 4}, {"text": "in", "start": 36, "end": 38, "id": 5}, {"text": "an", "start": 39, "end": 41, "id": 6}, {"text": "asymptomatic", "start": 42, "end": 54, "id": 7}, {"text": "60-year", "start": 55, "end": 62, "id": 8}, {"text": "-", "start": 62, "end": 63, "id": 9}, {"text": "old", "start": 63, "end": 66, "id": 10}, {"text": "woman", "start": 67, "end": 72, "id": 11}, {"text": "with", "start": 73, "end": 77, "id": 12}, {"text": "a", "start": 78, "end": 79, "id": 13}, {"text": "palpable", "start": 80, "end": 88, "id": 14}, {"text": "mass", "start": 89, "end": 93, "id": 15}, {"text": "found", "start": 94, "end": 99, "id": 16}, {"text": "at", "start": 100, "end": 102, "id": 17}, {"text": "pelvic", "start": 103, "end": 109, "id": 18}, {"text": "examination", "start": 110, "end": 121, "id": 19}, {"text": ".", "start": 121, "end": 122, "id": 20}, {"text": "(", "start": 123, "end": 124, "id": 21}, {"text": "a", "start": 124, "end": 125, "id": 22}, {"text": ")", "start": 125, "end": 126, "id": 23}, {"text": "Coronal", "start": 127, "end": 134, "id": 24}, {"text": "T2-weighted", "start": 135, "end": 146, "id": 25}, {"text": "MR", "start": 147, "end": 149, "id": 26}, {"text": "image", "start": 150, "end": 155, "id": 27}, {"text": "shows", "start": 156, "end": 161, "id": 28}, {"text": "a", "start": 162, "end": 163, "id": 29}, {"text": "multiseptated", "start": 164, "end": 177, "id": 30}, {"text": "cystic", "start": 178, "end": 184, "id": 31}, {"text": "mass", "start": 185, "end": 189, "id": 32}, {"text": "(", "start": 190, "end": 191, "id": 33}, {"text": "arrows", "start": 191, "end": 197, "id": 34}, {"text": ")", "start": 197, "end": 198, "id": 35}, {"text": "along", "start": 199, "end": 204, "id": 36}, {"text": "the", "start": 205, "end": 208, "id": 37}, {"text": "peritoneal", "start": 209, "end": 219, "id": 38}, {"text": "surfaces", "start": 220, "end": 228, "id": 39}, {"text": "of", "start": 229, "end": 231, "id": 40}, {"text": "the", "start": 232, "end": 235, "id": 41}, {"text": "uterus", "start": 236, "end": 242, "id": 42}, {"text": "and", "start": 243, "end": 246, "id": 43}, {"text": "broad", "start": 247, "end": 252, "id": 44}, {"text": "ligaments", "start": 253, "end": 262, "id": 45}, {"text": ".", "start": 262, "end": 263, "id": 46}, {"text": "(", "start": 264, "end": 265, "id": 47}, {"text": "b", "start": 265, "end": 266, "id": 48}, {"text": ")", "start": 266, "end": 267, "id": 49}, {"text": "Sagittal", "start": 268, "end": 276, "id": 50}, {"text": "gadolinium", "start": 277, "end": 287, "id": 51}, {"text": "-", "start": 287, "end": 288, "id": 52}, {"text": "enhanced", "start": 288, "end": 296, "id": 53}, {"text": "MR", "start": 297, "end": 299, "id": 54}, {"text": "image", "start": 300, "end": 305, "id": 55}, {"text": "reveals", "start": 306, "end": 313, "id": 56}, {"text": "enhancement", "start": 314, "end": 325, "id": 57}, {"text": "of", "start": 326, "end": 328, "id": 58}, {"text": "the", "start": 329, "end": 332, "id": 59}, {"text": "septa", "start": 333, "end": 338, "id": 60}, {"text": "(", "start": 339, "end": 340, "id": 61}, {"text": "arrow", "start": 340, "end": 345, "id": 62}, {"text": ")", "start": 345, "end": 346, "id": 63}, {"text": "and", "start": 347, "end": 350, "id": 64}, {"text": "extension", "start": 351, "end": 360, "id": 65}, {"text": "of", "start": 361, "end": 363, "id": 66}, {"text": "the", "start": 364, "end": 367, "id": 67}, {"text": "mass", "start": 368, "end": 372, "id": 68}, {"text": "into", "start": 373, "end": 377, "id": 69}, {"text": "the", "start": 378, "end": 381, "id": 70}, {"text": "cul", "start": 382, "end": 385, "id": 71}, {"text": "-", "start": 385, "end": 386, "id": 72}, {"text": "de", "start": 386, "end": 388, "id": 73}, {"text": "-", "start": 388, "end": 389, "id": 74}, {"text": "sac", "start": 389, "end": 392, "id": 75}, {"text": ".", "start": 392, "end": 393, "id": 76}]}
{"pdf_hash": "5dc31e32c3cfba28fc6081104018d00249ff44ba", "fig_key": "Figure6", "fig_uri": "11-Figure6-1.png", "text": "Figure 6. Mutant Mcm2p-HA localization in crm1 strain. Cytoplasmic mutant Mcm2p-HA proteins do not accumulate in the nucleus in the nuclear export\u2013defective strain crm1-809. Cells harboring a plasmid encoding wild-type or mutant Mcm2 proteins were grown at the restrictive temperature (17\u00b0C) for 6 h before fixation for immunofluorescence analysis. Wild-type Mcm2p was overproduced by induction in the absence of thiamine for 16 h followed by incubation at 17\u00b0C for 6 h. Cells were visualized with anti-HA antibody. (A) Wild-type Mcm2p; (B) overexpressed wild-type Mcm2p; (C) zinc finger mutant Mcm2p-M2; (D) NLS mutant Mcm2p-M9; (E) NLS mutant Mcm2p-M10; (F) carboxy-terminal truncation Mcm2p-D6; (G) amino-terminal truncation Mcm2p-D7; and (H) MCM core domain deletion Mcm2p-D10. 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{"pdf_hash": "fd79208cb52ee45e6563d9d2ac6bcabc7c59a7d1", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Computed tomography of the chest in a 48-year-old man who sustained blunt chest trauma. (A, B) There is a suspicious bronchial injury (arrow) on the right lower lobe and severe bilateral lung contusions.", "width": 1418, "height": 706, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "d5015109-e5b4-49ee-befb-73769b280772", "label": "a", "points": [[9.3, 0.7], [9.3, 699.7], [706, 699.7], [706, 0.7]], "color": "yellow"}, {"id": "807a1568-5ae1-470a-8594-0bfd462cc81b", "label": "a", "points": [[715, 5.2], [715, 695.2], [1416.2, 695.2], [1416.2, 5.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Computed", "start": 8, "end": 16, "id": 4}, {"text": "tomography", "start": 17, "end": 27, "id": 5}, {"text": "of", "start": 28, "end": 30, "id": 6}, {"text": "the", "start": 31, "end": 34, "id": 7}, {"text": "chest", "start": 35, "end": 40, "id": 8}, {"text": "in", "start": 41, "end": 43, "id": 9}, {"text": "a", "start": 44, "end": 45, "id": 10}, {"text": "48-year", "start": 46, "end": 53, "id": 11}, {"text": "-", "start": 53, "end": 54, "id": 12}, {"text": "old", "start": 54, "end": 57, "id": 13}, {"text": "man", "start": 58, "end": 61, "id": 14}, {"text": "who", "start": 62, "end": 65, "id": 15}, {"text": "sustained", "start": 66, "end": 75, "id": 16}, {"text": "blunt", "start": 76, "end": 81, "id": 17}, {"text": "chest", "start": 82, "end": 87, "id": 18}, {"text": "trauma", "start": 88, "end": 94, "id": 19}, {"text": ".", "start": 94, "end": 95, "id": 20}, {"text": "(", "start": 96, "end": 97, "id": 21}, {"text": "A", "start": 97, "end": 98, "id": 22}, {"text": ",", "start": 98, "end": 99, "id": 23}, {"text": "B", "start": 100, "end": 101, "id": 24}, {"text": ")", "start": 101, "end": 102, "id": 25}, {"text": "There", "start": 103, "end": 108, "id": 26}, {"text": "is", "start": 109, "end": 111, "id": 27}, {"text": "a", "start": 112, "end": 113, "id": 28}, {"text": "suspicious", "start": 114, "end": 124, "id": 29}, {"text": "bronchial", "start": 125, "end": 134, "id": 30}, {"text": "injury", "start": 135, "end": 141, "id": 31}, {"text": "(", "start": 142, "end": 143, "id": 32}, {"text": "arrow", "start": 143, "end": 148, "id": 33}, {"text": ")", "start": 148, "end": 149, "id": 34}, {"text": "on", "start": 150, "end": 152, "id": 35}, {"text": "the", "start": 153, "end": 156, "id": 36}, {"text": "right", "start": 157, "end": 162, "id": 37}, {"text": "lower", "start": 163, "end": 168, "id": 38}, {"text": "lobe", "start": 169, "end": 173, "id": 39}, {"text": "and", "start": 174, "end": 177, "id": 40}, {"text": "severe", "start": 178, "end": 184, "id": 41}, {"text": "bilateral", "start": 185, "end": 194, "id": 42}, {"text": "lung", "start": 195, "end": 199, "id": 43}, {"text": "contusions", "start": 200, "end": 210, "id": 44}, {"text": ".", "start": 210, "end": 211, "id": 45}]}
{"pdf_hash": "00e81776217141f35ea49725f5e3202146716416", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "FIGURE 4. Evaluation of the postoperative computed tomography data using SimPlant 11.04 (Materialise Dental Inc): (A) determination of the midpoint from the medial and distal edges of the frontozygomatic sutures; (B) drawing a vertical line to the zygomatic bone from the midpoint to set the point of intersection with the soft tissue. 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{"pdf_hash": "907fcfcb6dc50bf4e55949c214aa20b9dbd5d6c8", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. PET activations displayed on the average MR brain image of the 10 subjects in which the initial resting nonthirsty state is compared with three conditions of thirst. a shows activation (arrow) in anterior quadrangular lobule (V) (coronal section y 5 242 and sagittal section x 5 18) when 50% of the hypertonic NaCl had been infused. b shows activation (arrow) in left lingula (I, II) (sagittal section x 5 22 and axial section z 5 28) when 100% of hypertonic NaCl had been infused. c shows activation (arrow) in the left posterior biventer (VIIIB) (sagittal section x 5 230) 3 min after drinking to satiation.", "width": 686, "height": 1142, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68], "b": [69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105], "c": [106, 107, 108, 109, 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{"pdf_hash": "f869ae431913ab3adf72f63f4908b98202b26c6c", "fig_key": "Figure8", "fig_uri": "6-Figure8-1.png", "text": "Figure 8: Tricuspid annulus positioned in the surgical view as: three-dimensional volumetric data (a), an Image Arena reconstruction (b), Image Arena reconstruction with increased transparency (c), and a simulation using HeartWorks (Inventive Medical Limited, London, UK) software (d). The HeartWorks image is annotated with the observed axis of maximal dynamism (green) and the axes routinely measured during imaging (yellow) (A: Anterior, AL: Anterolateral, AS: Anteroseptal, AV: Aortic valve, L: Lateral, MV: Mitral valve, P: Posterior, PL: Posterolateral, PS: Posteroseptal, S: Septal, TV: Tricuspid valve) d c", "width": 674, "height": 548, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 21, 22, 23, 24, 25, 26, 27], "c": [32, 33, 34, 3, 4, 5, 6, 7, 8, 9, 10, 11, 35, 36, 37, 29, 30, 31], "d": [3, 4, 5, 6, 7, 8, 9, 10, 11, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82]}, "subfigures": [{"id": "afeac790-0cdb-475d-92f3-7cee3ca234b1", "label": "a", "points": [[-0.5, 2.1], [-0.5, 250.2], [283.8, 250.2], [283.8, 2.1]], "color": "yellow"}, {"id": 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{"pdf_hash": "deb12d0d15909a044d24803533650a469ff8b7c7", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Figure 4 (A) Orthopantomogram of a girl at the age of 8 years 10 months. All premolars in the upper jaw and all permanent molars in the lower jaw are missing, together with the second lower premolars. (B) In order to initiate a mesial movement of the molars, the deciduous upper second molars were removed at 8 years 10 months. Note the favourable space closure. (C) During mesial movement, the molars overerupt due to lack of opposing molars, 9 years 8 months of age. (D) At 16 years of age the molars have been intruded and further mesially moved by placement of transpalatal arches 4-5 mm away from the palatal mucosa. The tongue function has moved the molars. (E) Intra-oral view of the orthodontic appliances. Note that the space after both the first and second deciduous molars is now completely closed. (F) Orthopantomogram showing good axial inclination of the moved molars. In the lower jaw an acrylic plate with steel balls is placed for preliminary planning of implant sites with the use of computed tomography. (G) Occlusal view of the upper dental arch at the end of active orthodontic treatment at 16 years of age. (H) Frontal view with good vertical dimension. Note attrition of lower deciduous incisor. In lateral segments a removable partial prosthesis now controls the vertical height and hinders overeruption of the upper molars. 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{"pdf_hash": "b00c92fbc7d1271fea84385567b69263e9b01b05", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 a Patient C MRI brain during third episode of HTLV encephalitis. Ill-defined T2w signal hyperintensity in the basis pontis. b Patient C brain MRI brain during fourth episode of HTLV encephalitis (while on ciclosporin). Coronal T2w sequence. Ill-defined T2 signal hyperintensity in the midbrain and pontine tegmentum. No swelling or pathological enhancement. Previous area of signal change now normalised", "width": 1000, "height": 516, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73]}, "subfigures": [{"id": "6ab79092-d122-4bc2-8b22-c167fabd1867", "label": "a", "points": [[6.6, 3.7], [6.6, 509.2], [516.9, 509.2], [516.9, 3.7]], "color": "yellow"}, {"id": "3284bf87-bdf4-46dc-bd44-fc33f4569850", "label": "b", "points": [[550, 6.8], [550, 514], [990.8, 514], [990.8, 6.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Patient", "start": 9, "end": 16, "id": 4}, {"text": "C", "start": 17, "end": 18, "id": 5}, {"text": "MRI", "start": 19, "end": 22, "id": 6}, {"text": "brain", "start": 23, "end": 28, "id": 7}, {"text": "during", "start": 29, "end": 35, "id": 8}, {"text": "third", "start": 36, "end": 41, "id": 9}, {"text": "episode", "start": 42, "end": 49, "id": 10}, {"text": "of", "start": 50, "end": 52, "id": 11}, {"text": "HTLV", "start": 53, "end": 57, "id": 12}, {"text": "encephalitis", "start": 58, "end": 70, "id": 13}, {"text": ".", "start": 70, "end": 71, "id": 14}, {"text": "Ill", "start": 72, "end": 75, "id": 15}, {"text": "-", "start": 75, "end": 76, "id": 16}, {"text": "defined", "start": 76, "end": 83, "id": 17}, {"text": "T2w", "start": 84, "end": 87, "id": 18}, {"text": "signal", "start": 88, "end": 94, "id": 19}, {"text": "hyperintensity", "start": 95, "end": 109, "id": 20}, {"text": "in", "start": 110, "end": 112, "id": 21}, {"text": "the", "start": 113, "end": 116, "id": 22}, {"text": "basis", "start": 117, "end": 122, "id": 23}, {"text": "pontis", "start": 123, "end": 129, "id": 24}, {"text": ".", "start": 129, "end": 130, "id": 25}, {"text": "b", "start": 131, "end": 132, "id": 26}, {"text": "Patient", "start": 133, "end": 140, "id": 27}, {"text": "C", "start": 141, "end": 142, "id": 28}, {"text": "brain", "start": 143, "end": 148, "id": 29}, {"text": "MRI", "start": 149, "end": 152, "id": 30}, {"text": "brain", "start": 153, "end": 158, "id": 31}, {"text": "during", "start": 159, "end": 165, "id": 32}, {"text": "fourth", "start": 166, "end": 172, "id": 33}, {"text": "episode", "start": 173, "end": 180, "id": 34}, {"text": "of", "start": 181, "end": 183, "id": 35}, {"text": "HTLV", "start": 184, "end": 188, "id": 36}, {"text": "encephalitis", "start": 189, "end": 201, "id": 37}, {"text": "(", "start": 202, "end": 203, "id": 38}, {"text": "while", "start": 203, "end": 208, "id": 39}, {"text": "on", "start": 209, "end": 211, "id": 40}, {"text": "ciclosporin", "start": 212, "end": 223, "id": 41}, {"text": ")", "start": 223, "end": 224, "id": 42}, {"text": ".", "start": 224, "end": 225, "id": 43}, {"text": "Coronal", "start": 226, "end": 233, "id": 44}, {"text": "T2w", "start": 234, "end": 237, "id": 45}, {"text": "sequence", "start": 238, "end": 246, "id": 46}, {"text": ".", "start": 246, "end": 247, "id": 47}, {"text": "Ill", "start": 248, "end": 251, "id": 48}, {"text": "-", "start": 251, "end": 252, "id": 49}, {"text": "defined", "start": 252, "end": 259, "id": 50}, {"text": "T2", "start": 260, "end": 262, "id": 51}, {"text": "signal", "start": 263, "end": 269, "id": 52}, {"text": "hyperintensity", "start": 270, "end": 284, "id": 53}, {"text": "in", "start": 285, "end": 287, "id": 54}, {"text": "the", "start": 288, "end": 291, "id": 55}, {"text": "midbrain", "start": 292, "end": 300, "id": 56}, {"text": "and", "start": 301, "end": 304, "id": 57}, {"text": "pontine", "start": 305, "end": 312, "id": 58}, {"text": "tegmentum", "start": 313, "end": 322, "id": 59}, {"text": ".", "start": 322, "end": 323, "id": 60}, {"text": "No", "start": 324, "end": 326, "id": 61}, {"text": "swelling", "start": 327, "end": 335, "id": 62}, {"text": "or", "start": 336, "end": 338, "id": 63}, {"text": "pathological", "start": 339, "end": 351, "id": 64}, {"text": "enhancement", "start": 352, "end": 363, "id": 65}, {"text": ".", "start": 363, "end": 364, "id": 66}, {"text": "Previous", "start": 365, "end": 373, "id": 67}, {"text": "area", "start": 374, "end": 378, "id": 68}, {"text": "of", "start": 379, "end": 381, "id": 69}, {"text": "signal", "start": 382, "end": 388, "id": 70}, {"text": "change", "start": 389, "end": 395, "id": 71}, {"text": "now", "start": 396, "end": 399, "id": 72}, {"text": "normalised", "start": 400, "end": 410, "id": 73}]}
{"pdf_hash": "2b741744624379c58c53e5594a95d3db3c831ee5", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 Thin section transmission electronmicrographs of plastic-embedded and stained retinoic acid-treated HL-60/S4 cells. a Low-magnification view of a single HL-60/S4 granulocytic cell with cross-section views of two large nuclear lobes and extensive ELCS. Scale bar 2 \u03bcm. b Cross-section views of ELCS (six panels) taken from tomographic reconstructions. Scale bar 200 nm. c Enlarged tomographic cross-section view of ELCS bridging between two nuclear lobes, accompanied (below) by a schematic representation of the same field. N nuclear lobe, C cytoplasm, ONM outer nuclear membrane, INM inner nuclear membrane. 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{"pdf_hash": "24b867c045c1be3210071718d13f92e0d2a0b381", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. Diagnosis of superior mesenteric artery (SMA) dissec tion with the characteristic finding of a \u201cdouble lumen sign\u201d of the SMA on axial views of computed tomography (CT) images (A) and/or dissected segment of SMA on selective mesenteric angiography or CT angiography (B).", "width": 1012, "height": 438, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "37843fd4-356d-464b-b9e2-cdb1e57e1355", "label": "a", "points": [[3.2, 6.4], [3.2, 433.3], [522.8, 433.3], [522.8, 6.4]], "color": "yellow"}, {"id": "5e3e2f9f-3828-493d-950f-4c764a35b801", "label": "b", "points": [[534, 433.3], [534, 3.2], [970.5, 3.2], [970.5, 433.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Diagnosis", "start": 8, "end": 17, "id": 4}, {"text": "of", "start": 18, "end": 20, "id": 5}, {"text": "superior", "start": 21, "end": 29, "id": 6}, {"text": "mesenteric", "start": 30, "end": 40, "id": 7}, {"text": "artery", "start": 41, "end": 47, "id": 8}, {"text": "(", "start": 48, "end": 49, "id": 9}, {"text": "SMA", "start": 49, "end": 52, "id": 10}, {"text": ")", "start": 52, "end": 53, "id": 11}, {"text": "dissec", "start": 54, "end": 60, "id": 12}, {"text": "tion", "start": 61, "end": 65, "id": 13}, {"text": "with", "start": 66, "end": 70, "id": 14}, {"text": "the", "start": 71, "end": 74, "id": 15}, {"text": "characteristic", "start": 75, "end": 89, "id": 16}, {"text": "finding", "start": 90, "end": 97, "id": 17}, {"text": "of", "start": 98, "end": 100, "id": 18}, {"text": "a", "start": 101, "end": 102, "id": 19}, {"text": "\u201c", "start": 103, "end": 104, "id": 20}, {"text": "double", "start": 104, "end": 110, "id": 21}, {"text": "lumen", "start": 111, "end": 116, "id": 22}, {"text": "sign", "start": 117, "end": 121, "id": 23}, {"text": "\u201d", "start": 121, "end": 122, "id": 24}, {"text": "of", "start": 123, "end": 125, "id": 25}, {"text": "the", "start": 126, "end": 129, "id": 26}, {"text": "SMA", "start": 130, "end": 133, "id": 27}, {"text": "on", "start": 134, "end": 136, "id": 28}, {"text": "axial", "start": 137, "end": 142, "id": 29}, {"text": "views", "start": 143, "end": 148, "id": 30}, {"text": "of", "start": 149, "end": 151, "id": 31}, {"text": "computed", "start": 152, "end": 160, "id": 32}, {"text": "tomography", "start": 161, "end": 171, "id": 33}, {"text": "(", "start": 172, "end": 173, "id": 34}, {"text": "CT", "start": 173, "end": 175, "id": 35}, {"text": ")", "start": 175, "end": 176, "id": 36}, {"text": "images", "start": 177, "end": 183, "id": 37}, {"text": "(", "start": 184, "end": 185, "id": 38}, {"text": "A", "start": 185, "end": 186, "id": 39}, {"text": ")", "start": 186, "end": 187, "id": 40}, {"text": "and/or", "start": 188, "end": 194, "id": 41}, {"text": "dissected", "start": 195, "end": 204, "id": 42}, {"text": "segment", "start": 205, "end": 212, "id": 43}, {"text": "of", "start": 213, "end": 215, "id": 44}, {"text": "SMA", "start": 216, "end": 219, "id": 45}, {"text": "on", "start": 220, "end": 222, "id": 46}, {"text": "selective", "start": 223, "end": 232, "id": 47}, {"text": "mesenteric", "start": 233, "end": 243, "id": 48}, {"text": "angiography", "start": 244, "end": 255, "id": 49}, {"text": "or", "start": 256, "end": 258, "id": 50}, {"text": "CT", "start": 259, "end": 261, "id": 51}, {"text": "angiography", "start": 262, "end": 273, "id": 52}, {"text": "(", "start": 274, "end": 275, "id": 53}, {"text": "B", "start": 275, "end": 276, "id": 54}, {"text": ")", "start": 276, "end": 277, "id": 55}, {"text": ".", "start": 277, "end": 278, "id": 56}]}
{"pdf_hash": "0b37d765e7a564159f8f8aff11cdc06d7c8da4fd", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5. A man with ASR XL THR who was 69 years old at the index operation. Time to first MRI (top) was 2.3 years. The time elapsed between imagings was 2.5 years. Both times, whole-blood Cr remained below 4 ppb. Whole-blood Co increased from 7.2 ppb to 16 ppb. MRI was repeated due to increase in whole-blood Co levels and occurrence of stiffness in the operated hip. Control imaging revealed a newly formed cystic lesion (type 1).", "width": 686, "height": 828, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [0]}, "subfigures": [{"id": "9bbcd015-d2b1-40c5-9ce1-0bddd8537a7e", "label": "a", "points": [[1.6, 0], [1.6, 370.6], [682.2, 370.6], [682.2, 0]], "color": "yellow"}, {"id": "5183168f-8226-44fd-a9fa-70764a7995c7", "label": "b", "points": [[1.6, 378.2], [1.6, 800.9], [684.4, 800.9], [684.4, 378.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "man", "start": 12, "end": 15, "id": 4}, {"text": "with", "start": 16, "end": 20, "id": 5}, {"text": "ASR", "start": 21, "end": 24, "id": 6}, {"text": "XL", "start": 25, "end": 27, "id": 7}, {"text": "THR", "start": 28, "end": 31, "id": 8}, {"text": "who", "start": 32, "end": 35, "id": 9}, {"text": 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{"pdf_hash": "2d0fc3ebd9de52a64cbc2bebac518b25e418aaba", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. (A) Contrast-enhanced computed tomography showed significant dilatation of the feeding artery and the draining vein at the right renal hilum. The dilated inferior vena cava (IVC) is indicated by arrows. One feeding artery (B) and two drainage veins (C) were visualized by transcatheter angiography. The venous sacs were filled with NBCA and Lipiodol\u00a9 (D). 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{"pdf_hash": "f0bde657fe5a178ff3784c496d3e1bbfb3daee7e", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. (A) The atlantoaxial subluxation with increased atlantoaxial distance was demonstrated in flexion position of lateral radiograph of cervical spine. (B) Intraoperative fluoroscopic examination of upper cervical spine after completion of insertion of 2 C1\u2013C2 transarticular screws. (C) Three years postoperatively, the atlantoaxial alignment was good without loss of reduction.", "width": 1004, "height": 1590, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "c": [45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "bb452629-8b75-40bc-b9f4-b09e5a929d78", "label": "a", "points": [[36.5, 25.4], [36.5, 580.5], [964.4, 580.5], [964.4, 25.4]], "color": "yellow"}, {"id": "cf4dd9be-8a46-46b6-96c5-b365169cd968", "label": "b", "points": [[38.1, 599.5], [38.1, 975.5], [964.4, 975.5], [964.4, 599.5]], "color": "cyan"}, {"id": "99f50cff-6ca4-4b0f-ad12-cc7fe1771200", "label": "c", "points": [[34.9, 997.7], [34.9, 1556], [967.5, 1556], [967.5, 997.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "The", "start": 14, "end": 17, "id": 6}, {"text": "atlantoaxial", "start": 18, "end": 30, "id": 7}, {"text": "subluxation", "start": 31, "end": 42, "id": 8}, {"text": "with", "start": 43, "end": 47, "id": 9}, {"text": "increased", "start": 48, "end": 57, "id": 10}, {"text": "atlantoaxial", "start": 58, "end": 70, "id": 11}, {"text": "distance", "start": 71, "end": 79, "id": 12}, {"text": "was", "start": 80, "end": 83, "id": 13}, {"text": "demonstrated", "start": 84, "end": 96, "id": 14}, {"text": "in", "start": 97, "end": 99, "id": 15}, {"text": "flexion", "start": 100, "end": 107, "id": 16}, {"text": "position", "start": 108, "end": 116, "id": 17}, {"text": "of", "start": 117, "end": 119, "id": 18}, {"text": "lateral", "start": 120, "end": 127, "id": 19}, {"text": "radiograph", "start": 128, "end": 138, "id": 20}, {"text": "of", "start": 139, "end": 141, "id": 21}, {"text": "cervical", "start": 142, "end": 150, "id": 22}, {"text": "spine", "start": 151, "end": 156, "id": 23}, {"text": ".", "start": 156, "end": 157, "id": 24}, {"text": "(", "start": 158, "end": 159, "id": 25}, {"text": "B", "start": 159, "end": 160, "id": 26}, {"text": ")", "start": 160, "end": 161, "id": 27}, {"text": "Intraoperative", "start": 162, "end": 176, "id": 28}, {"text": "fluoroscopic", "start": 177, "end": 189, "id": 29}, {"text": "examination", "start": 190, "end": 201, "id": 30}, {"text": "of", "start": 202, "end": 204, "id": 31}, {"text": "upper", "start": 205, "end": 210, "id": 32}, {"text": "cervical", "start": 211, "end": 219, "id": 33}, {"text": "spine", "start": 220, "end": 225, "id": 34}, {"text": "after", "start": 226, "end": 231, "id": 35}, {"text": "completion", "start": 232, "end": 242, "id": 36}, {"text": "of", "start": 243, "end": 245, "id": 37}, {"text": "insertion", "start": 246, "end": 255, "id": 38}, {"text": "of", "start": 256, "end": 258, "id": 39}, {"text": "2", "start": 259, "end": 260, "id": 40}, {"text": "C1\u2013C2", "start": 261, "end": 266, "id": 41}, {"text": "transarticular", "start": 267, "end": 281, "id": 42}, {"text": "screws", "start": 282, "end": 288, "id": 43}, {"text": ".", "start": 288, "end": 289, "id": 44}, {"text": "(", "start": 290, "end": 291, "id": 45}, {"text": "C", "start": 291, "end": 292, "id": 46}, {"text": ")", "start": 292, "end": 293, "id": 47}, {"text": "Three", "start": 294, "end": 299, "id": 48}, {"text": "years", "start": 300, "end": 305, "id": 49}, {"text": "postoperatively", "start": 306, "end": 321, "id": 50}, {"text": ",", "start": 321, "end": 322, "id": 51}, {"text": "the", "start": 323, "end": 326, "id": 52}, {"text": "atlantoaxial", "start": 327, "end": 339, "id": 53}, {"text": "alignment", "start": 340, "end": 349, "id": 54}, {"text": "was", "start": 350, "end": 353, "id": 55}, {"text": "good", "start": 354, "end": 358, "id": 56}, {"text": "without", "start": 359, "end": 366, "id": 57}, {"text": "loss", "start": 367, "end": 371, "id": 58}, {"text": "of", "start": 372, "end": 374, "id": 59}, {"text": "reduction", "start": 375, "end": 384, "id": 60}, {"text": ".", "start": 384, "end": 385, "id": 61}]}
{"pdf_hash": "fc7717917699bac1280190af02be005d1edd2232", "fig_key": "Figure11", "fig_uri": "17-Figure11-1.png", "text": "Figure 11. Cerebellar agenesis in a 15-year-old girl who presented with severe cognitive impairment and tetraspasticity. (a) Sagittal T2-weighted MR image shows near-complete absence of cerebellar structures except for a rudimentary remnant of the anterior vermis (arrow), an enlarged posterior fossa, and marked hypoplasia of the pons. (b) Axial T2-weighted MR image shows rudimentary cerebellar tissue (arrows) projecting lateral to the brainstem. 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{"pdf_hash": "e2b6bf29ee7131742b78b5cdcc54cea1d6877d7b", "fig_key": "Figure4", "fig_uri": "28-Figure4-1.png", "text": "Figure 4: Transaxial CT (A), PET (B), and fused PET/CT (C) 68Ga-PSMA ligand PET/CT scan demonstrating moderately increased, focal PSMA ligand uptake in a comma-shaped soft tissue structure between the left adrenal gland and the aorta, indicating normal variant uptake in a coeliac ganglion.", "width": 1536, "height": 402, "subcaptions": {"a": [3, 4, 5, 6, 7, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63], "b": [9, 10, 11, 12, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63], "c": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "df23e7c3-3d06-4691-9df5-d98b0775b90c", "label": "a", "points": [[18.3, 6.9], [18.3, 392.7], [501.1, 392.7], [501.1, 6.9]], "color": "yellow"}, {"id": "27baf56f-8549-4a71-8dd5-68b01172891e", "label": "b", "points": [[523, 6.9], [523, 400], [1042.2, 400], [1042.2, 6.9]], "color": "cyan"}, {"id": "828eb892-ac49-4bdd-adc3-97401e65b13b", "label": "c", "points": [[1064.1, 4.5], [1064.1, 400], [1527.5, 400], [1527.5, 4.5]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Transaxial", "start": 10, "end": 20, "id": 3}, {"text": "CT", "start": 21, "end": 23, "id": 4}, {"text": "(", "start": 24, "end": 25, "id": 5}, {"text": "A", "start": 25, "end": 26, "id": 6}, {"text": ")", "start": 26, "end": 27, "id": 7}, {"text": ",", "start": 27, "end": 28, "id": 8}, {"text": "PET", "start": 29, "end": 32, "id": 9}, {"text": "(", "start": 33, "end": 34, "id": 10}, {"text": "B", "start": 34, "end": 35, "id": 11}, {"text": ")", "start": 35, "end": 36, "id": 12}, {"text": ",", "start": 36, "end": 37, "id": 13}, {"text": "and", "start": 38, "end": 41, "id": 14}, {"text": "fused", "start": 42, "end": 47, "id": 15}, {"text": "PET", "start": 48, "end": 51, "id": 16}, {"text": "/", "start": 51, "end": 52, "id": 17}, {"text": "CT", "start": 52, "end": 54, "id": 18}, {"text": "(", "start": 55, "end": 56, "id": 19}, {"text": "C", "start": 56, "end": 57, "id": 20}, {"text": ")", "start": 57, "end": 58, "id": 21}, {"text": "68Ga", "start": 59, "end": 63, "id": 22}, {"text": "-", "start": 63, "end": 64, "id": 23}, {"text": "PSMA", "start": 64, "end": 68, "id": 24}, {"text": "ligand", "start": 69, "end": 75, "id": 25}, {"text": "PET", "start": 76, "end": 79, "id": 26}, {"text": "/", "start": 79, "end": 80, "id": 27}, {"text": "CT", "start": 80, "end": 82, "id": 28}, {"text": "scan", "start": 83, "end": 87, "id": 29}, {"text": "demonstrating", "start": 88, "end": 101, "id": 30}, {"text": "moderately", "start": 102, "end": 112, "id": 31}, {"text": "increased", "start": 113, "end": 122, "id": 32}, {"text": ",", "start": 122, "end": 123, "id": 33}, {"text": "focal", "start": 124, "end": 129, "id": 34}, {"text": "PSMA", "start": 130, "end": 134, "id": 35}, {"text": "ligand", "start": 135, "end": 141, "id": 36}, {"text": "uptake", "start": 142, "end": 148, "id": 37}, {"text": "in", "start": 149, "end": 151, "id": 38}, {"text": "a", "start": 152, "end": 153, "id": 39}, {"text": "comma", "start": 154, "end": 159, "id": 40}, {"text": "-", "start": 159, "end": 160, "id": 41}, {"text": "shaped", "start": 160, "end": 166, "id": 42}, {"text": "soft", "start": 167, "end": 171, "id": 43}, {"text": "tissue", "start": 172, "end": 178, "id": 44}, {"text": "structure", "start": 179, "end": 188, "id": 45}, {"text": "between", "start": 189, "end": 196, "id": 46}, {"text": "the", "start": 197, "end": 200, "id": 47}, {"text": "left", "start": 201, "end": 205, "id": 48}, {"text": "adrenal", "start": 206, "end": 213, "id": 49}, {"text": "gland", "start": 214, "end": 219, "id": 50}, {"text": "and", "start": 220, "end": 223, "id": 51}, {"text": "the", "start": 224, "end": 227, "id": 52}, {"text": "aorta", "start": 228, "end": 233, "id": 53}, {"text": ",", "start": 233, "end": 234, "id": 54}, {"text": "indicating", "start": 235, "end": 245, "id": 55}, {"text": "normal", "start": 246, "end": 252, "id": 56}, {"text": "variant", "start": 253, "end": 260, "id": 57}, {"text": "uptake", "start": 261, "end": 267, "id": 58}, {"text": "in", "start": 268, "end": 270, "id": 59}, {"text": "a", "start": 271, "end": 272, "id": 60}, {"text": "coeliac", "start": 273, "end": 280, "id": 61}, {"text": "ganglion", "start": 281, "end": 289, "id": 62}, {"text": ".", "start": 289, "end": 290, "id": 63}]}
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{"pdf_hash": "bb25f811f094fa6b776862698ad31263d4e2bac9", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "FIG. 6. Representative in vivo pelvis PDFF maps for Cartesian R \u00bc 1, Cartesian R \u00bc 4 and radial R \u00bc 1 for a representative subject in axial and coronal orientations. The red squares indicate regions of interest in the bone marrow, prostate, muscle, and subcutaneous fat for this subject. 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{"pdf_hash": "6cef3209d90e3b8376ae5aa75f5a5f24dd933ff6", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "FIGURE 1 Nuclear import of dye-labeled vRNP. (A) A DIC image of an injected cell. (B) A fluorescence image of the same cell, taken 30 min after vRNP injection, showing nuclear import of the labeled vRNPs. Scale bars: 10 mm. (C) Nuclear import kinetics of labeled and unlabeled vRNPs. The amount of vRNPs in the cytoplasm and nucleus were quantified using Cy3 fluorescence and antinucleoprotein immunofluorescence for the labeled and unlabeled vRNPs, respectively. F in and F out indicate, respectively, the average fluorescence intensities inside and outside the nucleus after subtraction of a background term determined from areas outside the injected cells. The t \u00bc 0 point indicates the time of injection. The value of F in /(F in 1 F out ) at t \u00bc 0 was determined by coinjecting WGA (5mg/ml) with labeled vRNP to block import. 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{"pdf_hash": "faa480fbf7e106820218a91cb5c7a1fa98ec1c16", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Figure 5 Coronal (left) and axial (right) computed tomography scans obtained 3 months postimplantation indicate the presence of the source seeds within the region of initial placement. Imaging also demonstrates postsurgical changes that are suggestive of fibrosis.", "width": 928, "height": 446, "subcaptions": {"a": [2, 3, 4, 5, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "6b7412ba-0ea9-4d07-af69-8f621d2d1753", "label": "a", "points": [[32.3, 2.9], [32.3, 414.9], [448.6, 414.9], [448.6, 2.9]], "color": "yellow"}, {"id": "b86ec6c5-b212-42cd-ab76-7758d9ebcf56", "label": "b", "points": [[457.4, 1.5], [457.4, 416.4], [894.3, 416.4], [894.3, 1.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": "Coronal", "start": 9, "end": 16, "id": 2}, {"text": "(", "start": 17, "end": 18, "id": 3}, {"text": "left", "start": 18, "end": 22, "id": 4}, {"text": ")", "start": 22, "end": 23, "id": 5}, {"text": "and", "start": 24, "end": 27, "id": 6}, {"text": "axial", "start": 28, "end": 33, "id": 7}, {"text": "(", "start": 34, "end": 35, "id": 8}, {"text": "right", "start": 35, "end": 40, "id": 9}, {"text": ")", "start": 40, "end": 41, "id": 10}, {"text": "computed", "start": 42, "end": 50, "id": 11}, {"text": "tomography", "start": 51, "end": 61, "id": 12}, {"text": "scans", "start": 62, "end": 67, "id": 13}, {"text": "obtained", "start": 68, "end": 76, "id": 14}, {"text": "3", "start": 77, "end": 78, "id": 15}, {"text": "months", "start": 79, "end": 85, "id": 16}, {"text": "postimplantation", "start": 86, "end": 102, "id": 17}, {"text": "indicate", "start": 103, "end": 111, "id": 18}, {"text": "the", "start": 112, "end": 115, "id": 19}, {"text": "presence", "start": 116, "end": 124, "id": 20}, {"text": "of", "start": 125, "end": 127, "id": 21}, {"text": "the", "start": 128, "end": 131, "id": 22}, {"text": "source", "start": 132, "end": 138, "id": 23}, {"text": "seeds", "start": 139, "end": 144, "id": 24}, {"text": "within", "start": 145, "end": 151, "id": 25}, {"text": "the", "start": 152, "end": 155, "id": 26}, {"text": "region", "start": 156, "end": 162, "id": 27}, {"text": "of", "start": 163, "end": 165, "id": 28}, {"text": "initial", "start": 166, "end": 173, "id": 29}, {"text": "placement", "start": 174, "end": 183, "id": 30}, {"text": ".", "start": 183, "end": 184, "id": 31}, {"text": "Imaging", "start": 185, "end": 192, "id": 32}, {"text": "also", "start": 193, "end": 197, "id": 33}, {"text": "demonstrates", "start": 198, "end": 210, "id": 34}, {"text": "postsurgical", "start": 211, "end": 223, "id": 35}, {"text": "changes", "start": 224, "end": 231, "id": 36}, {"text": "that", "start": 232, "end": 236, "id": 37}, {"text": "are", "start": 237, "end": 240, "id": 38}, {"text": "suggestive", "start": 241, "end": 251, "id": 39}, {"text": "of", "start": 252, "end": 254, "id": 40}, {"text": "fibrosis", "start": 255, "end": 263, "id": 41}, {"text": ".", "start": 263, "end": 264, "id": 42}]}
{"pdf_hash": "ea05b2906307dbc43b9ce1799062bd74e403237a", "fig_key": "Figure30", "fig_uri": "26-Figure30-1.png", "text": "Figure 30. Diffusion-weighted MR imaging in a 9-month-old girl with abusive head injury. (a) Axial unenhanced CT scan obtained on the day the child presented with seizure shows right hemispheric sulcal effacement, loss of gray-white matter differentiation, and a thin rim of extraaxial blood along the right convexity and in the interhemispheric region (arrows). (b) Axial T1-weighted (516/12) MR image obtained the same day as the CT scan reveals low signal intensity of the right temporal and occipital lobes (white arrows) and high-signal-intensity SDH over the convexities, in the posterior interhemispheric region, and in the tentorial incisura (black arrows). (c) Axial T2-weighted (3,200/99) MR image at the same level and from the same day reveals increased signal intensity of the right temporal and occipital lobes (black arrows) and high-signal-intensity SDH over the convexities bilaterally (white arrows). (d) Diffusion-weighted (9,999/96) MR image obtained the same day reveals marked elevated signal intensity throughout the right hemisphere compatible with restricted free water diffusion.", "width": 1340, "height": 1542, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68], "b": [69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128], "c": [129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178], "d": [179, 180, 181, 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{"pdf_hash": "3fe355ed71d3eaf1c9a0d0b9663fd09a4c2ef30b", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. 3D porous media for direct visualization of bacteria motion. (a) Schematic of 3D porous media made by jammed packings of hydrogel particles, shown as grey circles, swollen in liquid LB medium. E. coli, shown in green, are dispersed at a low concentration within the pores between the particles. The packing is transparent, enabling imaging within the 3D pore space; inset shows a micrograph of a GFP-labeled bacterium. Scale bar represents 2 \u03bcm. (b) Time-projection of a 200 nm fluorescent tracer particle as it diffuses through the pore space, showing tortuous channels, each composed of a series of randomly-oriented, directed paths. Scale bar represents 5 \u03bcm. 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{"pdf_hash": "b2c4348dda42ae31a37fb6ad61637cdff3cac564", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1A-H A 29-year-old man with scaphoid nonunion and proximal pole avascular necrosis (AVN) with good clinical outcome following surgery. A Preoperative posteroanterior wrist radiograph demonstrates diffuse sclerosis within the proximal pole of the scaphoid and pseudoarthrosis (arrow). B Preoperative coronal T1-weighted MR image (TR: 460, TE: 16) shows decreased marrow signal intensity within the scaphoid proximal pole (*) and additionally in the distal pole (*) with pseudoarthrosis (arrows). C Corresponding Short Tau Inversion Recovery (STIR) MR image (TI: 90, TR: 3800, TE: 19) shows decreased marrow signal intensity in the proximal pole (*) and increased signal intensity within the distal pole of the scaphoid. D Fat-saturated T1-weighted MR image (TR: 600, TE: 17) after contrast enhancement shows increased contrast enhancement within the proximal and distal pole of scaphoid. E Postoperative T1-weighted MR image (TR: 600, TE: 17) shows some evidence of normalizing marrow signal within the proximal pole (arrow) and evidence of union on MR imaging. Some persistent decreased signal intensity remains within both the proximal and distal poles, though this has markedly improved compared with the preoperative imaging. F STIR image (TI: 90, TR: 3840, TE: 19) shows increased signal intensity within the marrow of the proximal scaphoid and decreasing signal within the distal pole of the scaphoid. G Fat-saturated T1-weighted MR image (TE: 480, TE: 17) after contrast enhancement shows absence of pseudoarthrosis and evidence of consolidation. 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{"pdf_hash": "3a70cba987d5b263a55a5b6d931f66c880cabdef", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Axial CT scans of adults aged 32\u201360 years showing bone abnormalities in the mandible. (a) Small non-expanding unilocular radiolucencies. (b) Large expanding multilocular bone abnormalities perforating and thinning the cortical border. (c) Thick cortical lining and areas of osteosclerosis. (d) Expanded and deformed/irregular cortical outline", "width": 1210, "height": 388, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "c": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "d": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "caf06c30-cf06-4862-85ef-8ae75c8de655", "label": "a", "points": [[25.2, 33.8], [25.2, 360.7], [310, 360.7], [310, 33.8]], "color": "yellow"}, {"id": "bc8baae6-4f40-4fbe-add4-a9a47338ca10", "label": "b", "points": [[317.7, 33.8], [317.7, 368.3], [600.6, 368.3], [600.6, 33.8]], "color": "cyan"}, {"id": "526ac440-3d17-4c80-a844-a825999de031", "label": "c", "points": [[614, 33.8], [614, 366.4], [896.9, 366.4], [896.9, 33.8]], "color": "magenta"}, {"id": "ba968648-1e6a-43e5-808a-a00639d4158c", "label": "d", "points": [[908.4, 37.6], [908.4, 366.4], [1183.7, 366.4], [1183.7, 37.6]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Axial", "start": 9, "end": 14, "id": 2}, {"text": "CT", "start": 15, "end": 17, "id": 3}, {"text": "scans", "start": 18, "end": 23, "id": 4}, {"text": "of", "start": 24, "end": 26, "id": 5}, {"text": "adults", "start": 27, "end": 33, "id": 6}, {"text": "aged", "start": 34, "end": 38, "id": 7}, {"text": "32\u201360", "start": 39, "end": 44, "id": 8}, {"text": "years", "start": 45, "end": 50, "id": 9}, {"text": "showing", "start": 51, "end": 58, "id": 10}, {"text": "bone", "start": 59, "end": 63, "id": 11}, {"text": "abnormalities", "start": 64, "end": 77, "id": 12}, {"text": "in", "start": 78, "end": 80, "id": 13}, {"text": "the", "start": 81, "end": 84, "id": 14}, {"text": "mandible", "start": 85, "end": 93, "id": 15}, {"text": ".", "start": 93, "end": 94, "id": 16}, {"text": "(", "start": 95, "end": 96, "id": 17}, {"text": "a", "start": 96, "end": 97, "id": 18}, {"text": ")", "start": 97, "end": 98, "id": 19}, {"text": "Small", "start": 99, "end": 104, "id": 20}, {"text": "non", "start": 105, "end": 108, "id": 21}, {"text": "-", "start": 108, "end": 109, "id": 22}, {"text": "expanding", "start": 109, "end": 118, "id": 23}, {"text": "unilocular", "start": 119, "end": 129, "id": 24}, {"text": "radiolucencies", "start": 130, "end": 144, "id": 25}, {"text": ".", "start": 144, "end": 145, "id": 26}, {"text": "(", "start": 146, "end": 147, "id": 27}, {"text": "b", "start": 147, "end": 148, "id": 28}, {"text": ")", "start": 148, "end": 149, "id": 29}, {"text": "Large", "start": 150, "end": 155, "id": 30}, {"text": "expanding", "start": 156, "end": 165, "id": 31}, {"text": "multilocular", "start": 166, "end": 178, "id": 32}, {"text": "bone", "start": 179, "end": 183, "id": 33}, {"text": "abnormalities", "start": 184, "end": 197, "id": 34}, {"text": "perforating", "start": 198, "end": 209, "id": 35}, {"text": "and", "start": 210, "end": 213, "id": 36}, {"text": "thinning", "start": 214, "end": 222, "id": 37}, {"text": "the", "start": 223, "end": 226, "id": 38}, {"text": "cortical", "start": 227, "end": 235, "id": 39}, {"text": "border", "start": 236, "end": 242, "id": 40}, {"text": ".", "start": 242, "end": 243, "id": 41}, {"text": "(", "start": 244, "end": 245, "id": 42}, {"text": "c", "start": 245, "end": 246, "id": 43}, {"text": ")", "start": 246, "end": 247, "id": 44}, {"text": "Thick", "start": 248, "end": 253, "id": 45}, {"text": "cortical", "start": 254, "end": 262, "id": 46}, {"text": "lining", "start": 263, "end": 269, "id": 47}, {"text": "and", "start": 270, "end": 273, "id": 48}, {"text": "areas", "start": 274, "end": 279, "id": 49}, {"text": "of", "start": 280, "end": 282, "id": 50}, {"text": "osteosclerosis", "start": 283, "end": 297, "id": 51}, {"text": ".", "start": 297, "end": 298, "id": 52}, {"text": "(", "start": 299, "end": 300, "id": 53}, {"text": "d", "start": 300, "end": 301, "id": 54}, {"text": ")", "start": 301, "end": 302, "id": 55}, {"text": "Expanded", "start": 303, "end": 311, "id": 56}, {"text": "and", "start": 312, "end": 315, "id": 57}, {"text": "deformed", "start": 316, "end": 324, "id": 58}, {"text": "/", "start": 324, "end": 325, "id": 59}, {"text": "irregular", "start": 325, "end": 334, "id": 60}, {"text": "cortical", "start": 335, "end": 343, "id": 61}, {"text": "outline", "start": 344, "end": 351, "id": 62}]}
{"pdf_hash": "477647894a66f56a6ce8d558a1422073bb45ed84", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Nuclear localization of the SlTIR1 protein fused to a GFP tag. Tobacco protoplasts were transiently transformed with either pro35S:GFP (A) or pro35S:SlTIR1-GFP (B) constructs. The subcellular localization of the SlTIR1\u2013GFP fusion protein or GFP alone was analysed by confocal laser scanning microscopy (left panel). Light micrographs (middle panel) and fluorescence (left panel) images are merged (right panel) to illustrate the different location of the two proteins.", "width": 930, "height": 620, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 38, 39, 40, 41, 42, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "b": [16, 17, 18, 19, 20, 21, 22, 23, 24, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "5c6d0969-6c28-4d35-8481-626d6ce1ce68", "label": "a", "points": [[3.4, 5.7], [3.4, 305.4], [927.5, 305.4], [927.5, 5.7]], "color": "yellow"}, {"id": "d846ca38-f826-4393-bba4-5135388f9921", "label": "b", "points": [[3.4, 324.5], [3.4, 609.5], [928.9, 609.5], [928.9, 324.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 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{"pdf_hash": "dbfe5c350aa5c65e4da29adadb2d22e8b99a964d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Transthoracic echocardiography image of pericardial effusion Figure 2. Thoracic computed tomography image of pericardial effusion", "width": 1498, "height": 732, "subcaptions": {"a": [0, 1, 2, 3, 4, 5, 6, 7, 8], "b": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18]}, "subfigures": [{"id": "f8636562-c101-4c8d-8147-0a7ea04fdbc7", "label": "a", "points": [[41.5, 46.9], [41.5, 572.3], [711.2, 572.3], [711.2, 46.9]], "color": "yellow"}, {"id": "397fdd4a-f0b7-4d95-8596-9d05af7e0deb", "label": "b", "points": [[742, 58.8], [742, 525], [1459, 525], [1459, 58.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Transthoracic", "start": 10, "end": 23, "id": 3}, {"text": "echocardiography", "start": 24, "end": 40, "id": 4}, {"text": "image", "start": 41, "end": 46, "id": 5}, {"text": "of", "start": 47, "end": 49, "id": 6}, {"text": "pericardial", "start": 50, "end": 61, "id": 7}, {"text": "effusion", "start": 62, "end": 70, "id": 8}, {"text": "Figure", "start": 71, "end": 77, "id": 9}, {"text": "2", "start": 78, "end": 79, "id": 10}, {"text": ".", "start": 79, "end": 80, "id": 11}, {"text": "Thoracic", "start": 81, "end": 89, "id": 12}, {"text": "computed", "start": 90, "end": 98, "id": 13}, {"text": "tomography", "start": 99, "end": 109, "id": 14}, {"text": "image", "start": 110, "end": 115, "id": 15}, {"text": "of", "start": 116, "end": 118, "id": 16}, {"text": "pericardial", "start": 119, "end": 130, "id": 17}, {"text": "effusion", "start": 131, "end": 139, "id": 18}]}
{"pdf_hash": "3d52fcb3c9fe1348f4384aa613c32820351a0adb", "fig_key": "Figure9", "fig_uri": "7-Figure9-1.png", "text": "Fig. 9 A 2-year-old girl with severe dysplastic mitral valve. Cardiac MRI images after administration of (a) gadobenate and (b) ferumoxytol show metallic scaffolding percutaneously delivered into the mitral position. Note sharper anatomical delineation and better blood pool to myocardium contrast of the ferumoxytol image than the gadobenate image", "width": 1018, "height": 408, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "87fb69b7-052c-443c-aed3-3e96ce6d0716", "label": "a", "points": [[1.9, 10.2], [1.9, 405.8], [513.3, 405.8], [513.3, 10.2]], "color": "yellow"}, {"id": "f2235a43-afa4-4bc9-8416-efae38a49b79", "label": "b", "points": [[523, 10.2], [523, 399.4], [1015.1, 399.4], [1015.1, 10.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "9", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "2-year", "start": 9, "end": 15, "id": 4}, {"text": "-", "start": 15, "end": 16, "id": 5}, {"text": "old", "start": 16, "end": 19, "id": 6}, {"text": "girl", "start": 20, "end": 24, "id": 7}, {"text": "with", "start": 25, "end": 29, "id": 8}, {"text": "severe", "start": 30, "end": 36, "id": 9}, {"text": "dysplastic", "start": 37, "end": 47, "id": 10}, {"text": "mitral", "start": 48, "end": 54, "id": 11}, {"text": "valve", "start": 55, "end": 60, "id": 12}, {"text": ".", "start": 60, "end": 61, "id": 13}, {"text": "Cardiac", "start": 62, "end": 69, "id": 14}, {"text": "MRI", "start": 70, "end": 73, "id": 15}, {"text": "images", "start": 74, "end": 80, "id": 16}, {"text": "after", "start": 81, "end": 86, "id": 17}, {"text": "administration", "start": 87, "end": 101, "id": 18}, {"text": "of", "start": 102, "end": 104, "id": 19}, {"text": "(", "start": 105, "end": 106, "id": 20}, {"text": "a", "start": 106, "end": 107, "id": 21}, {"text": ")", "start": 107, "end": 108, "id": 22}, {"text": "gadobenate", "start": 109, "end": 119, "id": 23}, {"text": "and", "start": 120, "end": 123, "id": 24}, {"text": "(", "start": 124, "end": 125, "id": 25}, {"text": "b", "start": 125, "end": 126, "id": 26}, {"text": ")", "start": 126, "end": 127, "id": 27}, {"text": "ferumoxytol", "start": 128, "end": 139, "id": 28}, {"text": "show", "start": 140, "end": 144, "id": 29}, {"text": "metallic", "start": 145, "end": 153, "id": 30}, {"text": "scaffolding", "start": 154, "end": 165, "id": 31}, {"text": "percutaneously", "start": 166, "end": 180, "id": 32}, {"text": "delivered", "start": 181, "end": 190, "id": 33}, {"text": "into", "start": 191, "end": 195, "id": 34}, {"text": "the", "start": 196, "end": 199, "id": 35}, {"text": "mitral", "start": 200, "end": 206, "id": 36}, {"text": "position", "start": 207, "end": 215, "id": 37}, {"text": ".", "start": 215, "end": 216, "id": 38}, {"text": "Note", "start": 217, "end": 221, "id": 39}, {"text": "sharper", "start": 222, "end": 229, "id": 40}, {"text": "anatomical", "start": 230, "end": 240, "id": 41}, {"text": "delineation", "start": 241, "end": 252, "id": 42}, {"text": "and", "start": 253, "end": 256, "id": 43}, {"text": "better", "start": 257, "end": 263, "id": 44}, {"text": "blood", "start": 264, "end": 269, "id": 45}, {"text": "pool", "start": 270, "end": 274, "id": 46}, {"text": "to", "start": 275, "end": 277, "id": 47}, {"text": "myocardium", "start": 278, "end": 288, "id": 48}, {"text": "contrast", "start": 289, "end": 297, "id": 49}, {"text": "of", "start": 298, "end": 300, "id": 50}, {"text": "the", "start": 301, "end": 304, "id": 51}, {"text": "ferumoxytol", "start": 305, "end": 316, "id": 52}, {"text": "image", "start": 317, "end": 322, "id": 53}, {"text": "than", "start": 323, "end": 327, "id": 54}, {"text": "the", "start": 328, "end": 331, "id": 55}, {"text": "gadobenate", "start": 332, "end": 342, "id": 56}, {"text": "image", "start": 343, "end": 348, "id": 57}]}
{"pdf_hash": "23a9d724dfc421bb197f3d044f57669d9e2dd6b6", "fig_key": "Figure7", "fig_uri": "34-Figure7-1.png", "text": "Figure 7: [68Ga]Ga-PSMA-617 PET/CT (1 h p.i.) demonstrating a very first patient with multiple lymph node metastases. Red arrows point to a representative lesion with a SUVmax of 36.5 and a tumor-to-background ratio of 52.1 one hour p.i.: (A) Contrast enhanced CT, (B) maximum intensity projection (MIP) of the PET scan 1 h p.i., (C) fusion of PET scan and contrast enhanced CT.", "width": 1022, "height": 1024, "subcaptions": {"a": [54, 55, 56, 57, 58, 59, 60], "b": [61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78], "c": [79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90]}, "subfigures": [{"id": "26bdb64b-ce2b-44ba-a583-234b87a810d3", "label": "a", "points": [[5.1, 0.5], [5.1, 526.9], [504, 526.9], [504, 0.5]], "color": "yellow"}, {"id": "2cfc4af3-c4c9-4505-a113-4506da3127f9", "label": "b", "points": [[510.5, 10.2], [510.5, 1014.5], [999.7, 1014.5], [999.7, 10.2]], "color": "cyan"}, {"id": "3da354b9-ede4-4486-a251-566036cea8c3", "label": "c", "points": [[6.7, 529], [6.7, 1018.2], [502.4, 1018.2], [502.4, 529]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, 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{"pdf_hash": "6039f8a9dc6cc3398673543931dfe4db44c272ba", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. A 65-year-old woman with an acute infarction of the right basal ganglia. A : A positive signal on magnetization-prepared rapid acquisition with gradient-echo image is defined by the location in the plaque and at least 2 image slices with at least 2-fold higher signal intensity compared to adjacent muscle (arrow). 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{"pdf_hash": "6160b8a2c7cccd451b3a13b7d5811af798a90613", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4 Top panel: Sagittal section of CT of abdomen performed five days after vesical lithotripsy showed urinary bladder distended with clots. But the outline of urinary bladder was intact. Bottom panel: Sagittal section of CT abdomen with oral positive contrast, performed 12 days after vesical lithotripsy (two days after cystoscopy and clot evacuation) when the patient developed abdominal distension: A large intra-peritoneal haematoma, at the superior aspect of dome of urinary bladder was seen which was in continuity with the lumen of the bladder. 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{"pdf_hash": "e6e75c4acc8274bbf60e6289c56616c3a5f42ea3", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Ultrasonographic finding of plantar fasciitis. (A) Thickening of the plantar fascia, Sagittal sonogram of 40-year-old man who had a clinical diagnosis of plantar fasciitis. (B) Normal sonographic finding of plantar fascia.", "width": 978, "height": 356, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "b1e50614-3a56-4c6f-ac9d-c9c8ed057811", "label": "a", "points": [[0, 3.1], [0, 352.3], [489.8, 352.3], [489.8, 3.1]], "color": "yellow"}, {"id": "0e895683-9fb9-45a2-8f41-30e5323f10cc", "label": "b", "points": [[494.4, 3.1], [494.4, 353.8], [971.9, 353.8], [971.9, 3.1]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Ultrasonographic", "start": 8, "end": 24, "id": 4}, {"text": "finding", "start": 25, "end": 32, "id": 5}, {"text": "of", "start": 33, "end": 35, "id": 6}, {"text": "plantar", "start": 36, "end": 43, "id": 7}, {"text": "fasciitis", "start": 44, "end": 53, "id": 8}, {"text": ".", "start": 53, "end": 54, "id": 9}, {"text": "(", "start": 55, "end": 56, "id": 10}, {"text": "A", "start": 56, "end": 57, "id": 11}, {"text": ")", "start": 57, "end": 58, "id": 12}, {"text": "Thickening", "start": 59, "end": 69, "id": 13}, {"text": "of", "start": 70, "end": 72, "id": 14}, {"text": "the", "start": 73, "end": 76, "id": 15}, {"text": "plantar", "start": 77, "end": 84, "id": 16}, {"text": "fascia", "start": 85, "end": 91, "id": 17}, {"text": ",", "start": 91, "end": 92, "id": 18}, {"text": "Sagittal", "start": 93, "end": 101, "id": 19}, {"text": "sonogram", "start": 102, "end": 110, "id": 20}, {"text": "of", "start": 111, "end": 113, "id": 21}, {"text": "40-year", "start": 114, "end": 121, "id": 22}, {"text": "-", "start": 121, "end": 122, "id": 23}, {"text": "old", "start": 122, "end": 125, "id": 24}, {"text": "man", "start": 126, "end": 129, "id": 25}, {"text": "who", "start": 130, "end": 133, "id": 26}, {"text": "had", "start": 134, "end": 137, "id": 27}, {"text": "a", "start": 138, "end": 139, "id": 28}, {"text": "clinical", "start": 140, "end": 148, "id": 29}, {"text": "diagnosis", "start": 149, "end": 158, "id": 30}, {"text": "of", "start": 159, "end": 161, "id": 31}, {"text": "plantar", "start": 162, "end": 169, "id": 32}, {"text": "fasciitis", "start": 170, "end": 179, "id": 33}, {"text": ".", "start": 179, "end": 180, "id": 34}, {"text": "(", "start": 181, "end": 182, "id": 35}, {"text": "B", "start": 182, "end": 183, "id": 36}, {"text": ")", "start": 183, "end": 184, "id": 37}, {"text": "Normal", "start": 185, "end": 191, "id": 38}, {"text": "sonographic", "start": 192, "end": 203, "id": 39}, {"text": "finding", "start": 204, "end": 211, "id": 40}, {"text": "of", "start": 212, "end": 214, "id": 41}, {"text": "plantar", "start": 215, "end": 222, "id": 42}, {"text": "fascia", "start": 223, "end": 229, "id": 43}, {"text": ".", "start": 229, "end": 230, "id": 44}]}
{"pdf_hash": "59a2336bff5eba2a11f0bf7318902a37f1d8832f", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Reproductive system-specific GAL4. (A) Scheme. The 4.4 Kb oamb genomic region containing oamb promoter region and part of the second intron was cloned upstream of promoterless-GAL4 in the pPTGAL vector. E, exon; +1, transcription initiation site. (B\u2013D) The RS-GAL4 expression pattern was visualized with UAS-mCD8::GFP. Strong GFP expression was detectable in the oviduct epithelium in the dissected reproduction system (B) and a sagittal section (C), but not in the central nervous system (D). Images were captured under fluorescent as well as dim light illumination to outline tissue morphologies. (E\u2013G) Sagittal sections of the CS (E), C380-GAL4/UAS-mCD8::GFP;P5391/+ (F) or dTdc2-GAL4/UASmCD8::GFP (G) female body were immunostained with anti-K3 (E, G) or anti-b-Galactosidase (F) followed by Alexa 555-labeled secondary antibodies. P5391 contains the enhancer P-element P[lArB] in the first oamb intron. 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{"pdf_hash": "be19f7b6243007bcc839fb8feaacd0a3718fba6e", "fig_key": "Figure3", "fig_uri": "8-Figure3-1.png", "text": "FIG. 3. (A) Transverse T2-weighted images at the C4\u20135, (B) C5\u20136, and (C) C6\u20137 intervertebral spaces of the same dog. Bilateral, lateral spinal cord compression secondary to articular joint process proliferation is present at all levels. Two of the three observers agreed on characterizing C6\u20137 as the main site of compression. One observer selected the C4\u20135 intervertebral space as the main site of compression. The presence of multiple, moderate-to-severe compressive sites in several of the dogs enrolled in the study likely resulted in the disagreements noted among different observers when evaluating the main site of spinal cord compression.", "width": 1252, "height": 390, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 24, 25, 26, 27, 28, 29, 30, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78], "b": [7, 8, 9, 10, 11, 14, 15, 16, 17, 24, 25, 26, 27, 28, 29, 30], "c": [7, 8, 9, 10, 11, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "ae184e66-9ac2-411f-a434-4f01a457adae", "label": "a", "points": [[22.8, 3.6], [22.8, 361.6], [408.5, 361.6], [408.5, 3.6]], "color": "yellow"}, {"id": "6d911804-f31d-4747-a1f2-c665c783d7a3", "label": "b", "points": [[422.4, 3.6], [422.4, 351.7], [817.9, 351.7], [817.9, 3.6]], "color": "cyan"}, {"id": "3bbf758d-483a-40d3-a9b8-7aaf7816ccbb", "label": "c", "points": 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{"pdf_hash": "0e91b7f6725207e9ead0c6c69f8a7f4e273d020c", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5. Computed tomography (CT) and magnetic resonance imaging (MRI) scanning images of a 58-year-old female with complicated Crohn disease. This patient presented with abdominal pain for >10 years, with a 3-month history of cloudy urine. Enhanced CT scanning showed a nidus with wall edema and mucosal thickness in the far end of the ileum (arrows in A), and the nidus invaded the bladder and shaped an eminence lesion, with a size of 38 \u00c2 23 mm (B). MRI scanning showed a mass convex to the enteric cavity of the ileum, with tresis and internal fistula (T2-weighted, C), and this inflammatory mass encroached on the anterosuperior bladder (T1-weighted, D).", "width": 966, "height": 682, "subcaptions": {"a": [3, 4, 5, 6, 7, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70], "b": [3, 4, 5, 6, 7, 47, 48, 49, 50, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95], "c": [9, 10, 11, 12, 13, 14, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119], "d": [128, 129, 130, 131, 132, 133, 134, 135, 9, 10, 11, 12, 13, 14, 96, 97, 98, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "2a16c41b-0d5b-4db9-b646-d994bd396d8a", "label": "a", "points": [[31.3, 27.2], [31.3, 329.4], [483, 329.4], [483, 27.2]], "color": "yellow"}, {"id": "47bca7d6-c7de-4fad-85d6-ab609dfcc2fe", "label": "b", "points": 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{"pdf_hash": "78d4142e3abcfcda14620bdd0c1db365c3825102", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Figure 6 Magnetic resonance imaging (MRI) in fetus with mild ventriculomegaly (VM) diagnosed on ultrasound. MRI was performed at 21 weeks\u2019 gestation, which confirmed mild VM/colpocephaly on axial image (a) but also showed agenesis of corpus callosum (a,b). Coronal image through face (c) and axial image at level of cerebellum (d) showed poor development of right globe leading to diagnosis of Aicardi syndrome. All these features were confirmed on autopsy.", "width": 656, "height": 768, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 52, 53], "b": [52, 42, 43, 44, 45, 46, 47, 48, 51, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 53], "c": [71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "1ff1f3a1-242a-4bcb-82ff-431cd889b265", "label": "a", "points": [[4.3, 1.4], [4.3, 363.1], [311.1, 363.1], [311.1, 1.4]], "color": "yellow"}, {"id": "f9d8ca69-aabb-4c87-8a9f-b66334434253", "label": "b", "points": [[315.2, 1.4], [315.2, 361], [654.1, 361], [654.1, 1.4]], "color": "cyan"}, {"id": "39ceb697-4e6e-4008-8c9b-7d57c013df65", "label": "c", "points": [[1.2, 369.3], [1.2, 763.1], [308, 763.1], [308, 369.3]], "color": "magenta"}, {"id": "51e7a474-defb-49cf-9712-4ac6459cc59c", "label": "d", "points": [[317.6, 364.9], [317.6, 767.3], [653.4, 767.3], [653.4, 364.9]], 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{"pdf_hash": "70a8e398e95ca215512049ea39cc1ebf994fe48c", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4. Pancreatic neuroendocrine tumor in a 47-year-old female. A 1.2 cm size, round, hyperattenuating mass (yellow arrow) was seen in the pancreas tail on computed tomography (A). The mass was well defined and displayed a hypoechoic, homogeneous pattern on endoscopic ultrasonography (B).", "width": 1338, "height": 554, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "dd669435-90a1-42cf-a464-d77c0d5025bb", "label": "a", "points": [[1.1, 39.8], [1.1, 519.6], [662.7, 519.6], [662.7, 39.8]], "color": "yellow"}, {"id": "a5505b77-9b42-48f7-b5eb-154da127a2ed", "label": "b", "points": [[679.6, 35.6], [679.6, 523.8], [1337, 523.8], [1337, 35.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Pancreatic", "start": 8, "end": 18, "id": 4}, {"text": "neuroendocrine", "start": 19, "end": 33, "id": 5}, {"text": "tumor", "start": 34, "end": 39, "id": 6}, {"text": "in", "start": 40, "end": 42, "id": 7}, {"text": "a", "start": 43, "end": 44, "id": 8}, {"text": "47-year", "start": 45, "end": 52, "id": 9}, {"text": "-", "start": 52, "end": 53, "id": 10}, {"text": "old", "start": 53, "end": 56, "id": 11}, {"text": "female", "start": 57, "end": 63, "id": 12}, {"text": ".", "start": 63, "end": 64, "id": 13}, {"text": "A", "start": 65, "end": 66, "id": 14}, {"text": "1.2", "start": 67, "end": 70, "id": 15}, {"text": "cm", "start": 71, "end": 73, "id": 16}, {"text": "size", "start": 74, "end": 78, "id": 17}, {"text": ",", "start": 78, "end": 79, "id": 18}, {"text": "round", "start": 80, "end": 85, "id": 19}, {"text": ",", "start": 85, "end": 86, "id": 20}, {"text": "hyperattenuating", "start": 87, "end": 103, "id": 21}, {"text": "mass", "start": 104, "end": 108, "id": 22}, {"text": "(", "start": 109, "end": 110, "id": 23}, {"text": "yellow", "start": 110, "end": 116, "id": 24}, {"text": "arrow", "start": 117, "end": 122, "id": 25}, {"text": ")", "start": 122, "end": 123, "id": 26}, {"text": "was", "start": 124, "end": 127, "id": 27}, {"text": "seen", "start": 128, "end": 132, "id": 28}, {"text": "in", "start": 133, "end": 135, "id": 29}, {"text": "the", "start": 136, "end": 139, "id": 30}, {"text": "pancreas", "start": 140, "end": 148, "id": 31}, {"text": "tail", "start": 149, "end": 153, "id": 32}, {"text": "on", "start": 154, "end": 156, "id": 33}, {"text": "computed", "start": 157, "end": 165, "id": 34}, {"text": "tomography", "start": 166, "end": 176, "id": 35}, {"text": "(", "start": 177, "end": 178, "id": 36}, {"text": "A", "start": 178, "end": 179, "id": 37}, {"text": ")", "start": 179, "end": 180, "id": 38}, {"text": ".", "start": 180, "end": 181, "id": 39}, {"text": "The", "start": 182, "end": 185, "id": 40}, {"text": "mass", "start": 186, "end": 190, "id": 41}, {"text": "was", "start": 191, "end": 194, "id": 42}, {"text": "well", "start": 195, "end": 199, "id": 43}, {"text": "defined", "start": 200, "end": 207, "id": 44}, {"text": "and", "start": 208, "end": 211, "id": 45}, {"text": "displayed", "start": 212, "end": 221, "id": 46}, {"text": "a", "start": 222, "end": 223, "id": 47}, {"text": "hypoechoic", "start": 224, "end": 234, "id": 48}, {"text": ",", "start": 234, "end": 235, "id": 49}, {"text": "homogeneous", "start": 236, "end": 247, "id": 50}, {"text": "pattern", "start": 248, "end": 255, "id": 51}, {"text": "on", "start": 256, "end": 258, "id": 52}, {"text": "endoscopic", "start": 259, "end": 269, "id": 53}, {"text": "ultrasonography", "start": 270, "end": 285, "id": 54}, {"text": "(", "start": 286, "end": 287, "id": 55}, {"text": "B", "start": 287, "end": 288, "id": 56}, {"text": ")", "start": 288, "end": 289, "id": 57}, {"text": ".", "start": 289, "end": 290, "id": 58}]}
{"pdf_hash": "c211299261252758866addda6169da45c931c2f0", "fig_key": "Figure5", "fig_uri": "10-Figure5-1.png", "text": "FIGURE 5 Data example showing estimates of three faWMTI parameters (branch 1) based on a 1\u20139\u20109 acquisition in live rat brain at an isotropic resolution of 300 \u03bcm. Axial and coronal slice planes are shown. The parameter values are overlaid on the b = 0 images from the 1\u20139\u20109 data set", "width": 1104, "height": 720, "subcaptions": {"a": [31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "a66da49d-b796-4b7d-9ab2-9d5c8dafcde8", "label": "a", "points": [[8.7, 3.5], [8.7, 711.6], [341.9, 711.6], [341.9, 3.5]], "color": "yellow"}, {"id": "f14ae9a3-cbf8-4a77-8495-d6dfc6e3cc6c", "label": "a", "points": [[394.2, 1.7], [394.2, 709.9], [732.5, 709.9], [732.5, 1.7]], "color": "cyan"}, {"id": "c16c1fea-1894-4dcc-8d46-5277cfd10a84", "label": "a", "points": [[786.6, 1.7], [786.6, 715.1], [1097.1, 715.1], [1097.1, 1.7]], "color": "magenta"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": "Data", "start": 9, "end": 13, "id": 2}, {"text": "example", "start": 14, "end": 21, "id": 3}, {"text": "showing", "start": 22, "end": 29, "id": 4}, {"text": "estimates", "start": 30, "end": 39, "id": 5}, {"text": "of", "start": 40, "end": 42, "id": 6}, {"text": "three", "start": 43, "end": 48, "id": 7}, {"text": "faWMTI", "start": 49, "end": 55, "id": 8}, {"text": "parameters", "start": 56, "end": 66, "id": 9}, {"text": "(", "start": 67, "end": 68, "id": 10}, {"text": "branch", "start": 68, "end": 74, "id": 11}, {"text": "1", "start": 75, "end": 76, "id": 12}, {"text": ")", "start": 76, "end": 77, "id": 13}, {"text": "based", "start": 78, "end": 83, "id": 14}, {"text": "on", "start": 84, "end": 86, "id": 15}, {"text": "a", "start": 87, "end": 88, "id": 16}, {"text": "1\u20139\u20109", "start": 89, "end": 94, "id": 17}, {"text": "acquisition", "start": 95, "end": 106, "id": 18}, {"text": "in", "start": 107, "end": 109, "id": 19}, {"text": "live", "start": 110, "end": 114, "id": 20}, {"text": "rat", "start": 115, "end": 118, "id": 21}, {"text": "brain", "start": 119, "end": 124, "id": 22}, {"text": "at", "start": 125, "end": 127, "id": 23}, {"text": "an", "start": 128, "end": 130, "id": 24}, {"text": "isotropic", "start": 131, "end": 140, "id": 25}, {"text": "resolution", "start": 141, "end": 151, "id": 26}, {"text": "of", "start": 152, "end": 154, "id": 27}, {"text": "300", "start": 155, "end": 158, "id": 28}, {"text": "\u03bcm", "start": 159, "end": 161, "id": 29}, {"text": ".", "start": 161, "end": 162, "id": 30}, {"text": "Axial", "start": 163, "end": 168, "id": 31}, {"text": "and", "start": 169, "end": 172, "id": 32}, {"text": "coronal", "start": 173, "end": 180, "id": 33}, {"text": "slice", "start": 181, "end": 186, "id": 34}, {"text": "planes", "start": 187, "end": 193, "id": 35}, {"text": "are", "start": 194, "end": 197, "id": 36}, {"text": "shown", "start": 198, "end": 203, "id": 37}, {"text": ".", "start": 203, "end": 204, "id": 38}, {"text": "The", "start": 205, "end": 208, "id": 39}, {"text": "parameter", "start": 209, "end": 218, "id": 40}, {"text": "values", "start": 219, "end": 225, "id": 41}, {"text": "are", "start": 226, "end": 229, "id": 42}, {"text": "overlaid", "start": 230, "end": 238, "id": 43}, {"text": "on", "start": 239, "end": 241, "id": 44}, {"text": "the", "start": 242, "end": 245, "id": 45}, {"text": "b", "start": 246, "end": 247, "id": 46}, {"text": "=", "start": 248, "end": 249, "id": 47}, {"text": "0", "start": 250, "end": 251, "id": 48}, {"text": "images", "start": 252, "end": 258, "id": 49}, {"text": "from", "start": 259, "end": 263, "id": 50}, {"text": "the", "start": 264, "end": 267, "id": 51}, {"text": "1\u20139\u20109", "start": 268, "end": 273, "id": 52}, {"text": "data", "start": 274, "end": 278, "id": 53}, {"text": "set", "start": 279, "end": 282, "id": 54}]}
{"pdf_hash": "9cc44c861e85fb27de40f2d710044e7dace0f101", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 Images retrieved from the hologram. a, Two-dimensional fast Fourier transformation of the hologram in Fig. 2. b, Zoomed-in image, obtained by subtracting the Fourier transformations of opposite-helicity holograms. Below are shown scan lines through the holographic image (red) and the STXM image in Fig. 1 (blue).", "width": 548, "height": 1324, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "d9e659f8-0106-429f-afeb-cb92eb7921dc", "label": "a", "points": [[38, 4.8], [38, 464.8], [536, 464.8], [536, 4.8]], "color": "yellow"}, {"id": "644a1b27-a79b-42aa-9cc7-21a3da52c3e7", "label": "b", "points": [[34, 493], [34, 1313], [540, 1313], [540, 493]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "Images", "start": 9, "end": 15, "id": 2}, {"text": "retrieved", "start": 16, "end": 25, "id": 3}, {"text": "from", "start": 26, "end": 30, "id": 4}, {"text": "the", "start": 31, "end": 34, "id": 5}, {"text": "hologram", "start": 35, "end": 43, "id": 6}, {"text": ".", "start": 43, "end": 44, "id": 7}, {"text": "a", "start": 45, "end": 46, "id": 8}, {"text": ",", "start": 46, "end": 47, "id": 9}, {"text": "Two", "start": 48, "end": 51, "id": 10}, {"text": "-", "start": 51, "end": 52, "id": 11}, {"text": "dimensional", "start": 52, "end": 63, "id": 12}, {"text": "fast", "start": 64, "end": 68, "id": 13}, {"text": "Fourier", "start": 69, "end": 76, "id": 14}, {"text": "transformation", "start": 77, "end": 91, "id": 15}, {"text": "of", "start": 92, "end": 94, "id": 16}, {"text": "the", "start": 95, "end": 98, "id": 17}, {"text": "hologram", "start": 99, "end": 107, "id": 18}, {"text": "in", "start": 108, "end": 110, "id": 19}, {"text": "Fig", "start": 111, "end": 114, "id": 20}, {"text": ".", "start": 114, "end": 115, "id": 21}, {"text": "2", "start": 116, "end": 117, "id": 22}, {"text": ".", "start": 117, "end": 118, "id": 23}, {"text": "b", "start": 119, "end": 120, "id": 24}, {"text": ",", "start": 120, "end": 121, "id": 25}, {"text": "Zoomed", "start": 122, "end": 128, "id": 26}, {"text": "-", "start": 128, "end": 129, "id": 27}, {"text": "in", "start": 129, "end": 131, "id": 28}, {"text": "image", "start": 132, "end": 137, "id": 29}, {"text": ",", "start": 137, "end": 138, "id": 30}, {"text": "obtained", "start": 139, "end": 147, "id": 31}, {"text": "by", "start": 148, "end": 150, "id": 32}, {"text": "subtracting", "start": 151, "end": 162, "id": 33}, {"text": "the", "start": 163, "end": 166, "id": 34}, {"text": "Fourier", "start": 167, "end": 174, "id": 35}, {"text": "transformations", "start": 175, "end": 190, "id": 36}, {"text": "of", "start": 191, "end": 193, "id": 37}, {"text": "opposite", "start": 194, "end": 202, "id": 38}, {"text": "-", "start": 202, "end": 203, "id": 39}, {"text": "helicity", "start": 203, "end": 211, "id": 40}, {"text": "holograms", "start": 212, "end": 221, "id": 41}, {"text": ".", "start": 221, "end": 222, "id": 42}, {"text": "Below", "start": 223, "end": 228, "id": 43}, {"text": "are", "start": 229, "end": 232, "id": 44}, {"text": "shown", "start": 233, "end": 238, "id": 45}, {"text": "scan", "start": 239, "end": 243, "id": 46}, {"text": "lines", "start": 244, "end": 249, "id": 47}, {"text": "through", "start": 250, "end": 257, "id": 48}, {"text": "the", "start": 258, "end": 261, "id": 49}, {"text": "holographic", "start": 262, "end": 273, "id": 50}, {"text": "image", "start": 274, "end": 279, "id": 51}, {"text": "(", "start": 280, "end": 281, "id": 52}, {"text": "red", "start": 281, "end": 284, "id": 53}, {"text": ")", "start": 284, "end": 285, "id": 54}, {"text": "and", "start": 286, "end": 289, "id": 55}, {"text": "the", "start": 290, "end": 293, "id": 56}, {"text": "STXM", "start": 294, "end": 298, "id": 57}, {"text": "image", "start": 299, "end": 304, "id": 58}, {"text": "in", "start": 305, "end": 307, "id": 59}, {"text": "Fig", "start": 308, "end": 311, "id": 60}, {"text": ".", "start": 311, "end": 312, "id": 61}, {"text": "1", "start": 313, "end": 314, "id": 62}, {"text": "(", "start": 315, "end": 316, "id": 63}, {"text": "blue", "start": 316, "end": 320, "id": 64}, {"text": ")", "start": 320, "end": 321, "id": 65}, {"text": ".", "start": 321, "end": 322, "id": 66}]}
{"pdf_hash": "65296e4ee9ece810ab4558cc99c2c10275e0ac8d", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5. A representative case of a 72-year-old male with Child -Pugh class A hepatic function (case 12 in the Tables 1 and 2). (a) Before radiotherapy, the tumor located in S7 extended to IVC and the intraluminal space was narrow in the CT images. The tumor was indicated by the red arrowhead. (b) Dose distribution of the treatment plan. A total tumor dose of 50 Gy was delivered in 25 fractions by a dynamic conformal arc with four static fields. (c) Three months after radiotherapy. S7 tumor disappeared and no enhancement defect was observed within IVC, and the treatment response was judged as a complete response. The patient died of hepatic failure 13.7 months after irradiation. The irradiated tumor had no sign of regrowth at the time of death. 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{"pdf_hash": "bc9726c35f317797001d0d1f559d5efbbe89383c", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "FIG. 4. Illustrations of DTA on CT images of three different trabecular bone samples (2.1 \u00d7 2.1 \u00d7 1.3 mm 3 ). (Left) Original CT image (full voxel model) of the trabecular bone sample. (Right) Skeletonized image (skeleton model). (A) Plate-to-rod ratio \u202b\u05e1\u202c 20.10, plate tissue fraction \u202b\u05e1\u202c 0.9526, Young's modulus \u202b\u05e1\u202c 974.8 MPa. (B) Plateto-rod ratio \u202b\u05e1\u202c 10.22, plate tissue fraction \u202b\u05e1\u202c 0.9109, Young's modulus \u202b\u05e1\u202c 674.8 MPa. 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{"pdf_hash": "e4310d9cd0e6c1757fa44b68659951d1b32494a0", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 a 18 F-fluorodeoxyglucose positron emission tomography/ computed tomography on Day 0 shows significant retroperitoneal lymphadenopathy. b 18 F-fluorodeoxyglucose positron emission tomography/computed tomography on Day 76 shows complete resolution of the retroperitoneal lymphadenopathy", "width": 652, "height": 574, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "283ef00c-8135-4bde-a316-93d1c639b313", "label": "a", "points": [[28.9, 20], [28.9, 545.3], [321.4, 545.3], [321.4, 20]], "color": "yellow"}, {"id": "34b62002-4ca5-4c61-8dce-7db898c48997", "label": "b", "points": [[330.7, 17.9], [330.7, 546.3], [621.1, 546.3], [621.1, 17.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "18", "start": 9, "end": 11, "id": 4}, {"text": "F", "start": 12, "end": 13, "id": 5}, {"text": "-", "start": 13, "end": 14, "id": 6}, {"text": "fluorodeoxyglucose", "start": 14, "end": 32, "id": 7}, {"text": "positron", "start": 33, "end": 41, "id": 8}, {"text": "emission", "start": 42, "end": 50, "id": 9}, {"text": "tomography/", "start": 51, "end": 62, "id": 10}, {"text": "computed", "start": 63, "end": 71, "id": 11}, {"text": "tomography", "start": 72, "end": 82, "id": 12}, {"text": "on", "start": 83, "end": 85, "id": 13}, {"text": "Day", "start": 86, "end": 89, "id": 14}, {"text": "0", "start": 90, "end": 91, "id": 15}, {"text": "shows", "start": 92, "end": 97, "id": 16}, {"text": "significant", "start": 98, "end": 109, "id": 17}, {"text": "retroperitoneal", "start": 110, "end": 125, "id": 18}, {"text": "lymphadenopathy", "start": 126, "end": 141, "id": 19}, {"text": ".", "start": 141, "end": 142, "id": 20}, {"text": "b", "start": 143, "end": 144, "id": 21}, {"text": "18", "start": 145, "end": 147, "id": 22}, {"text": "F", "start": 148, "end": 149, "id": 23}, {"text": "-", "start": 149, "end": 150, "id": 24}, {"text": "fluorodeoxyglucose", "start": 150, "end": 168, "id": 25}, {"text": "positron", "start": 169, "end": 177, "id": 26}, {"text": "emission", "start": 178, "end": 186, "id": 27}, {"text": "tomography", "start": 187, "end": 197, "id": 28}, {"text": "/", "start": 197, "end": 198, "id": 29}, {"text": "computed", "start": 198, "end": 206, "id": 30}, {"text": "tomography", "start": 207, "end": 217, "id": 31}, {"text": "on", "start": 218, "end": 220, "id": 32}, {"text": "Day", "start": 221, "end": 224, "id": 33}, {"text": "76", "start": 225, "end": 227, "id": 34}, {"text": "shows", "start": 228, "end": 233, "id": 35}, {"text": "complete", "start": 234, "end": 242, "id": 36}, {"text": "resolution", "start": 243, "end": 253, "id": 37}, {"text": "of", "start": 254, "end": 256, "id": 38}, {"text": "the", "start": 257, "end": 260, "id": 39}, {"text": "retroperitoneal", "start": 261, "end": 276, "id": 40}, {"text": "lymphadenopathy", "start": 277, "end": 292, "id": 41}]}
{"pdf_hash": "7ebc3b260408fe35561147e28217234f8ea7836a", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 (a) Late phase fluorescein angiogram demonstrates an extrafoveal choroidal neovascular membrane associated with agerelated macular generation with subretinal fluid, with a best-corrected visual acuity (BCVA) of 20/80. (b) Spectral domain optical coherence tomography (SD-OCT) of the lesion shows a hyporreflective image confirming subretinal fluid at baseline. (c) Late phase fluorescein angiogram, and (d) SD-OCT demonstrate a complete resolution of subretinal fluid, with a BCVA of 20/25 at 6 months of follow up, after doses of intravitreal adalimumab and bevacizumab. 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{"pdf_hash": "f14e365973e34c90bc9ced741a4c073f37e4ac8c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. A: an arterial spin labeling (ASL) measure of regional pulmonary blood flow (in ml min 1 cm 3) after correction for coil heterogeneity and absolute quantification of perfusion in a representative subject lying supine in the magnetic resonance scanner. This is a sagittal slice of the mid-right lung at functional residual capacity. The posterior lung is at the bottom of the image and region adjacent to the diaphragm is visible as the concave region on the left side of the image. The division of the right lung unto upper, middle, and lower lobes is visible. The signal intensity of the images scales as a function of perfusion, with brighter regions representing areas of greater blood flow. B: Fast Low-Angle SHot (FLASH) proton density (g/cm3) measures of regional lung density in the lung same slice as in A. 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{"pdf_hash": "7b3af2b05f3cf2eb9845925d3aa981ff8038b4e7", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Dmrt5 regulates regionally specific mesencephalic gene expression in the chicken embryo. Na\u00efve chick midbrain neuroepithelium was electroporated with a mouse Dmrt5 expressing plasmid and hybridized for chick Mab21l2 or Foxa2 at st.17. (A) Frontal view (Left) and coronal midbrain section (Center) illustrating the loss of Mab21l2 expression (black arrowheads) in ectopic Dmrt5-expressing (Right) tissue (white arrowhead). 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{"pdf_hash": "89921e9660ec37d808bbf0e92c32347a1844c9ae", "fig_key": "Figure12", "fig_uri": "15-Figure12-1.png", "text": "Fig. 12 Tentacles. a Longitudinal ultrathin section of distal tentacle in specimen #675 with coelomic cavity (ct) surrounded by myoepithelial cells (mte), parts of prototroch (pr) ventral to tentacle; b\u2013e series of ultrathin sections through region of connection between mesoderm of tentacles and first segment of specimen #308; arrows point to ECM of mesoderm; b epithelio-muscle cells (mu) surrounded by epidermis in tentacle; c solid mesoderm strand (mte) surrounded by epidermis in tentacle; d, e merging of mesoderm of first segment (m1) with mesoderm of tentacle (mte), foregut (fg)", "width": 1018, "height": 1336, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "c": [45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 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{"pdf_hash": "cbdbb6427d34a8a54cc50cc6d9fdc412fdb67d80", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "FIG. 5. Cellular and nuclear morphology indicative of apoptosis and necrosis can be seen in N2a cells treated with Al-malt. Cells were treated with Al-malt and maltolate at the indicated concentrations for 24 h and then examined by light microscopy (all 3200) and scanning electron microscopy (SEM). CHX was added to some cell cultures 30 min before the addition of Al-malt. (a) control phase contrast; (b) control H33258; (c) 500 mM Al-malt phase contrast; (d) 500 mM Al-malt H33258; (e) CHX phase contrast; (f ) CHX H33258; (g) 500 mM Al-malt 1 CHX phase contrast; (h) 500 mM Al-malt 1 CHX H33258; (i) control SEM; ( j) 500 mM Al-malt SEM. 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{"pdf_hash": "db459b8290e78d7039039fec445bc195ab3cf5c9", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4: a) Harvesting of the ab\u00acdominal fat graft using a 4cm transverse side incision below the umbilicus; b) Frontal sinus right side cavity obliteration with abdominal fat graft", "width": 668, "height": 440, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "37c82868-9023-41fe-a2a1-d71ad3ca8653", "label": "a", "points": [[5.5, 29.9], [5.5, 407.7], [330.5, 407.7], [330.5, 29.9]], "color": "yellow"}, {"id": "b516349c-8929-47c0-82b8-e487f95d01f1", "label": "b", "points": [[343.2, 31], [343.2, 407.7], [658.7, 407.7], [658.7, 31]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Harvesting", "start": 13, "end": 23, "id": 5}, {"text": "of", "start": 24, "end": 26, "id": 6}, {"text": "the", "start": 27, "end": 30, "id": 7}, {"text": "ab\u00acdominal", "start": 31, "end": 41, "id": 8}, {"text": "fat", "start": 42, "end": 45, "id": 9}, {"text": "graft", "start": 46, "end": 51, "id": 10}, {"text": "using", "start": 52, "end": 57, "id": 11}, {"text": "a", "start": 58, "end": 59, "id": 12}, {"text": "4", "start": 60, "end": 61, "id": 13}, {"text": "cm", "start": 61, "end": 63, "id": 14}, {"text": "transverse", "start": 64, "end": 74, "id": 15}, {"text": "side", "start": 75, "end": 79, "id": 16}, {"text": "incision", "start": 80, "end": 88, "id": 17}, {"text": "below", "start": 89, "end": 94, "id": 18}, {"text": "the", "start": 95, "end": 98, "id": 19}, {"text": "umbilicus", "start": 99, "end": 108, "id": 20}, {"text": ";", "start": 108, "end": 109, "id": 21}, {"text": "b", "start": 110, "end": 111, "id": 22}, {"text": ")", "start": 111, "end": 112, "id": 23}, {"text": "Frontal", "start": 113, "end": 120, "id": 24}, {"text": "sinus", "start": 121, "end": 126, "id": 25}, {"text": "right", "start": 127, "end": 132, "id": 26}, {"text": "side", "start": 133, "end": 137, "id": 27}, {"text": "cavity", "start": 138, "end": 144, "id": 28}, {"text": "obliteration", "start": 145, "end": 157, "id": 29}, {"text": "with", "start": 158, "end": 162, "id": 30}, {"text": "abdominal", "start": 163, "end": 172, "id": 31}, {"text": "fat", "start": 173, "end": 176, "id": 32}, {"text": "graft", "start": 177, "end": 182, "id": 33}]}
{"pdf_hash": "549d0506b619f340d1e683bedf9725c691cca4df", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. (A) Chest X-rays. A large homogenous shadow in the right upper and middle lung fields and a reticular shadow are present in the left middle lung field. (B) Computed tomography (CT) of the chest. Massive infiltration of the right middle lung field was observed. (c) Sagittal T1 weighted magnetic resonance imaging (MRI) of the lumbar spine. A vertebral body fracture was found at the level of L1 (white arrows). (D) postmortem pathological studies. Fat emboli including bone marrow cells were observed in the pulmonary artery (He stain, 100\u00d7). (e) postmortem pathological studies. Bone marrow cells were present in an arteriole in the submucosa of the colon (He stain, 400\u00d7). (F) Postmortem pathological studies. Higher magnification of the same section showed many myelocytes and erythroblasts (He stain, 1000\u00d7).", "width": 634, "height": 798, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "c": [59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91], "d": [92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117], "e": [118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145], "f": [146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170]}, "subfigures": [{"id": "0e88c6e0-d6ab-4599-a3e2-c20b3c911d34", 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{"pdf_hash": "1f52a83fa4b65f985ed335138e2e85155f0660cb", "fig_key": "Figure7", "fig_uri": "4-Figure7-1.png", "text": "Fig. 7. A. Panoramic radiograph showing hyperplasia of the right coronoid processes. B, C. Sagittal computed tomography scans from case 4 showing hyperplasia of the right coronoid processes. The elongated right coronoid process had impinged on the zygomatic arch (arrow). Sung-Min Kim et al: Mouth opening limitation caused by coronoid hyperplasia: a report of four cases. 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{"pdf_hash": "696596a2a64d8209817ff0a3aea80e294fb2f944", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 (A) Transoesophageal echocardiogram of the patient with an aneurysm of the interatrial septum. The aneurysm bulges into the right atrium and two small defects (indicated by the arrows) are identified in this longitudinal plane. A left to right colour jet can be seen passing through the upper defect. (B) Two Amplatzer septal occluders have been placed. The arrows indicate each of the devices, which are aligned sequentially on the atrial septum. There was no residual flow on contrast echocardiography. 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{"pdf_hash": "5c68ddc9a375a8ebccc52bc59e1eecec1e290766", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. A case of an 18-year-old female with a falling injury. (A, B) Preoperative and (C, D) 6-month postoperative coronal and sagittal section of computed tomography.", "width": 1230, "height": 630, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 17, 18, 19, 20, 21, 22, 31], "b": [32, 33, 34, 35, 36, 37, 38, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "166b3ae6-ed84-41fa-a51e-8f3252d7f22e", "label": "a", "points": [[-0.9, 1.6], [-0.9, 310.6], [605.3, 310.6], [605.3, 1.6]], "color": "yellow"}, {"id": "f53b53b4-be1b-492a-8d09-0cd08e324c5e", "label": "a", "points": [[622.8, 3.6], [622.8, 316.4], [1225.2, 316.4], [1225.2, 3.6]], "color": "cyan"}, {"id": "70241375-3174-4ef2-8b4e-e77135b497b6", "label": "b", "points": [[8.8, 326.1], [8.8, 627.3], [613.1, 627.3], [613.1, 326.1]], "color": "magenta"}, {"id": "2def4608-309e-48f3-ac16-46ecd1b5a4d6", "label": "b", "points": [[628.6, 324.2], [628.6, 625.3], [1225.2, 625.3], [1225.2, 324.2]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": "case", "start": 10, "end": 14, "id": 5}, {"text": "of", "start": 15, "end": 17, "id": 6}, {"text": "an", "start": 18, "end": 20, "id": 7}, {"text": "18-year", "start": 21, "end": 28, "id": 8}, {"text": "-", "start": 28, "end": 29, "id": 9}, {"text": "old", "start": 29, "end": 32, "id": 10}, {"text": "female", "start": 33, "end": 39, "id": 11}, {"text": "with", "start": 40, "end": 44, "id": 12}, {"text": "a", "start": 45, "end": 46, "id": 13}, {"text": "falling", "start": 47, "end": 54, "id": 14}, {"text": "injury", "start": 55, "end": 61, "id": 15}, {"text": ".", "start": 61, "end": 62, "id": 16}, {"text": "(", "start": 63, "end": 64, "id": 17}, {"text": "A", "start": 64, "end": 65, "id": 18}, {"text": ",", "start": 65, "end": 66, "id": 19}, {"text": "B", "start": 67, "end": 68, "id": 20}, {"text": ")", "start": 68, "end": 69, "id": 21}, {"text": "Preoperative", "start": 70, "end": 82, "id": 22}, {"text": "and", "start": 83, "end": 86, "id": 23}, {"text": "(", "start": 87, "end": 88, "id": 24}, {"text": "C", "start": 88, "end": 89, "id": 25}, {"text": ",", "start": 89, "end": 90, "id": 26}, {"text": "D", "start": 91, "end": 92, "id": 27}, {"text": ")", "start": 92, "end": 93, "id": 28}, {"text": "6-month", "start": 94, "end": 101, "id": 29}, {"text": "postoperative", "start": 102, "end": 115, "id": 30}, {"text": "coronal", "start": 116, "end": 123, "id": 31}, {"text": "and", "start": 124, "end": 127, "id": 32}, {"text": "sagittal", "start": 128, "end": 136, "id": 33}, {"text": "section", "start": 137, "end": 144, "id": 34}, {"text": "of", "start": 145, "end": 147, "id": 35}, {"text": "computed", "start": 148, "end": 156, "id": 36}, {"text": "tomography", "start": 157, "end": 167, "id": 37}, {"text": ".", "start": 167, "end": 168, "id": 38}]}
{"pdf_hash": "8ac7983090cd5927644ff9908c1ea270755ac7a4", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "FIGURE 3. Immunohistochemical staining of conjunctival specimens obtained from patients with SLK or Mooren ulcer using anti\u2013IL-33 antibody. Frozen sections made from conjunctival specimens obtained from a patient with SLK (A) and a patient with Mooren ulcer (B, C) were stained by polyclonal anti\u2013IL-33 antibody. Nuclear IL-33 staining was observed in the vascular endothelium. Double immunostaining was carried out with anti\u2013PNAd (HEV) antibody (C). Original magnification, 200 .", "width": 1000, "height": 332, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "b": [22, 23, 24, 25, 26, 27, 28, 29, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "c": [22, 23, 24, 25, 26, 27, 28, 29, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83]}, "subfigures": [{"id": "af6cb43c-bd98-4541-aee2-5f1a02cd8548", "label": "a", "points": [[1.6, 1.3], [1.6, 328.3], [333.4, 328.3], [333.4, 1.3]], "color": "yellow"}, {"id": "ae34af91-78d3-490c-b553-b9d0311dea75", "label": "b", "points": [[336.5, 1.3], [336.5, 331.5], [663.5, 331.5], [663.5, 1.3]], "color": "cyan"}, {"id": "47e5b3f5-fc96-4e21-ba9c-250ecae91b79", "label": "b", "points": [[668.3, 2.9], 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{"pdf_hash": "767c967cf055ed04bd28f8b00e860d9e6e66f9ae", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1: head MRI: (A) sagittal T1-WI; (B) coronal T2-WI; (C) sagittal post contrast T1-WI; (D) diffusion WI; (E) FLAIR; (F) MRS: demonstrate left upper cerebellar hemisphere intra axial lesion, well defined, with striated appearance on T2-WI, which not enhance after gadolinium injection. This lesion appear with high intensity in FLAIR and DWI and moderately decreased choline (cho)/Cr ratio", "width": 678, "height": 494, "subcaptions": {"a": [6, 7, 8, 9, 10, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 60, 61, 62, 63, 64, 65, 66], "b": [12, 13, 14, 15, 16, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "c": [18, 19, 20, 21, 22, 23, 24, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 60, 61, 62, 63, 64, 65, 66], "d": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 26, 27, 28, 29, 30], "e": [32, 33, 34, 35, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 76, 77, 78, 79, 80, 81, 82, 83], "f": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "ed977456-f13c-46df-9d8b-de3f11a84a0c", "label": "a", "points": [[2.7, 3.2], [2.7, 202.4], [222.3, 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{"pdf_hash": "f09f4c4b0a89829c0d70a575cebe0a004427ba37", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Figure 6 (A) T1-weighted SEMAC-VAT image, of a 49-year-old male who underwent THA on his left hip joint, showing nonuniform signals in the soft tissue (white arrow head). (B) T2-weighted TIRM SEMAC-VAT image, of a 49-year-old male who underwent THA on his left hip joint, showing a high signal at the soft tissue (white arrow head). (C) DR image, of a 49-year-old male who underwent THA on his left hip joint, showing suspicious lucency around the implant. However, it was not confirmed in the revision surgery, so we considered it to be a false positive. (D) Pathological findings showing fibrous hyperplasia and metallic particles (white arrows). The patient was finally diagnosed with metallosis, which is a kind of adverse local tissue reaction (ALTR). 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{"pdf_hash": "0ca6718b46342cb37909cff62b042f53c018e617", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2: Spiral computerized tomography slice showing (a) primary molar in sagittal view, (b) axial view showing canal volume at coronal third, (c) canal volume at middle third, (d) canal volume at apical third, (e) Three\u2011dimensional view of canal volume from coronal to 1 mm short of apical third", "width": 676, "height": 862, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15], "b": [3, 4, 5, 6, 7, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "c": [32, 33, 34, 3, 4, 5, 6, 7, 35, 36, 29, 30, 31], "d": [3, 4, 5, 6, 7, 38, 39, 40, 41, 42, 43, 44, 45], "e": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "1953b9f5-a6e2-4268-957e-59ed059d3989", "label": "a", "points": [[8.7, 1.4], [8.7, 270.5], [329.1, 270.5], [329.1, 1.4]], "color": "yellow"}, {"id": "0cce1363-2e39-4bde-b3d1-036e5b556d8a", "label": "b", "points": [[345.1, 4.6], [345.1, 271.6], [669.8, 271.6], [669.8, 4.6]], "color": "cyan"}, {"id": "1aa2a881-a51a-4d2e-bf7e-4d8259d650c5", "label": "c", "points": [[9.8, 279.1], [9.8, 543.9], [325.9, 543.9], [325.9, 279.1]], "color": "magenta"}, {"id": "5b00a0db-5e5c-48ce-bb67-b90b130420e6", "label": "d", "points": [[340.8, 280.2], [340.8, 553.5], [674, 553.5], [674, 280.2]], "color": "springgreen"}, {"id": "8de2946e-6204-4652-aaa4-eabeb3472637", "label": "e", "points": [[179.6, 548.6], [179.6, 822], [520.3, 822], [520.3, 548.6]], "color": "tomato"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Spiral", "start": 10, "end": 16, "id": 3}, {"text": "computerized", "start": 17, "end": 29, "id": 4}, {"text": "tomography", "start": 30, "end": 40, "id": 5}, {"text": "slice", "start": 41, "end": 46, "id": 6}, {"text": "showing", "start": 47, "end": 54, "id": 7}, {"text": "(", "start": 55, "end": 56, "id": 8}, {"text": "a", "start": 56, "end": 57, "id": 9}, {"text": ")", "start": 57, "end": 58, "id": 10}, {"text": "primary", "start": 59, "end": 66, "id": 11}, {"text": "molar", "start": 67, "end": 72, "id": 12}, {"text": "in", "start": 73, "end": 75, "id": 13}, {"text": "sagittal", "start": 76, "end": 84, "id": 14}, {"text": "view", "start": 85, "end": 89, "id": 15}, {"text": ",", "start": 89, "end": 90, "id": 16}, {"text": "(", "start": 91, "end": 92, "id": 17}, {"text": "b", "start": 92, "end": 93, "id": 18}, {"text": ")", "start": 93, "end": 94, "id": 19}, {"text": "axial", "start": 95, "end": 100, "id": 20}, {"text": "view", "start": 101, "end": 105, "id": 21}, {"text": "showing", "start": 106, "end": 113, "id": 22}, {"text": "canal", "start": 114, "end": 119, "id": 23}, {"text": "volume", "start": 120, "end": 126, "id": 24}, {"text": "at", "start": 127, "end": 129, "id": 25}, {"text": "coronal", "start": 130, "end": 137, "id": 26}, {"text": "third", "start": 138, "end": 143, "id": 27}, {"text": ",", "start": 143, "end": 144, "id": 28}, {"text": "(", "start": 145, "end": 146, "id": 29}, {"text": "c", "start": 146, "end": 147, "id": 30}, {"text": ")", "start": 147, "end": 148, "id": 31}, {"text": "canal", "start": 149, "end": 154, "id": 32}, {"text": "volume", "start": 155, "end": 161, "id": 33}, {"text": "at", "start": 162, "end": 164, "id": 34}, {"text": "middle", "start": 165, "end": 171, "id": 35}, {"text": "third", "start": 172, "end": 177, "id": 36}, {"text": ",", "start": 177, "end": 178, "id": 37}, {"text": "(", "start": 179, "end": 180, "id": 38}, {"text": "d", "start": 180, "end": 181, "id": 39}, {"text": ")", "start": 181, "end": 182, "id": 40}, {"text": "canal", "start": 183, "end": 188, "id": 41}, {"text": "volume", "start": 189, "end": 195, "id": 42}, {"text": "at", "start": 196, "end": 198, "id": 43}, {"text": "apical", "start": 199, "end": 205, "id": 44}, {"text": "third", "start": 206, "end": 211, "id": 45}, {"text": ",", "start": 211, "end": 212, "id": 46}, {"text": "(", "start": 213, "end": 214, "id": 47}, {"text": "e", "start": 214, "end": 215, "id": 48}, {"text": ")", "start": 215, "end": 216, "id": 49}, {"text": "Three\u2011dimensional", "start": 217, "end": 234, "id": 50}, {"text": "view", "start": 235, "end": 239, "id": 51}, {"text": "of", "start": 240, "end": 242, "id": 52}, {"text": "canal", "start": 243, "end": 248, "id": 53}, {"text": "volume", "start": 249, "end": 255, "id": 54}, {"text": "from", "start": 256, "end": 260, "id": 55}, {"text": "coronal", "start": 261, "end": 268, "id": 56}, {"text": "to", "start": 269, "end": 271, "id": 57}, {"text": "1", "start": 272, "end": 273, "id": 58}, {"text": "mm", "start": 274, "end": 276, "id": 59}, {"text": "short", "start": 277, "end": 282, "id": 60}, {"text": "of", "start": 283, "end": 285, "id": 61}, {"text": "apical", "start": 286, "end": 292, "id": 62}, {"text": "third", "start": 293, "end": 298, "id": 63}]}
{"pdf_hash": "4b90dca408d6c1ca625662e62f92fdcb4d568285", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2 Parametric images of DA D2 receptor density coregistered with MRI images windowed to demonstrate [ 18 F]fallypride-b.p.'s in (a) the anterior and ventral striatum on a coronal image, (b) the medial thalamus on an axial image, (c) the substantia nigra, colliculi, and temporal cortex on an axial image through the midbrain, and (d) the amygdala and temporal cortex on an axial image through the uncus of the temporal lobes.", "width": 1138, "height": 1072, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "c": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 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{"pdf_hash": "36876c04932cd62107bf4eb2e52e01f9a7ef5dc3", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Macroscopic findings of the abdominal aorta. A: The wall was irregularly thick and the lumen was rough. B: Contrast-enhanced computed tomography of the abdomen on the 16th hospital day showed the irregular wall of the abdominal aorta (circle). C: Both the renal arteries (*1: right, *2: left) and celiac artery (*3) were occluded at the origin. *4: superior mesenteric artery.", "width": 946, "height": 744, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "c": [50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86]}, "subfigures": [{"id": "79a1306e-7455-43e1-b6cc-b0f2b56d6e97", "label": "a", "points": [[2.2, 0], [2.2, 345.2], [490.9, 345.2], [490.9, 0]], "color": "yellow"}, {"id": "021f05e5-afdd-471e-b821-00a3f0e6c470", "label": "b", "points": [[499.9, 0], [499.9, 491.7], [942.3, 491.7], [942.3, 0]], "color": "cyan"}, {"id": "b6c9ffdc-42d4-4b75-a7c1-563372a9f33b", "label": "c", "points": [[2.2, 355.7], [2.2, 739.8], [486.5, 739.8], [486.5, 355.7]], "color": "magenta"}], "tokens": [{"text": 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{"pdf_hash": "8b5207192fa4435724323fc69c92c7e5d3d45b76", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Representative case (62 years old) of HER2-negative classical apocrine carcinoma (G2) (Simple Stain-Max method after heat-induced antigen retrieval). Apocrine-type cancer cells showing plump, eosinophilic cytoplasm in H&E (a) are negative for ER (b), but with nuclear staining for AR (c). HER2 is only weakly (1\u00fe) stained on the plasma membrane (d), while p53 is strongly positive in the nuclei (e). 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{"pdf_hash": "91dbd3a6538ede73fbd2db8e50c706a35dc8f05c", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1. Transaxial fused positron emission tomographycomputed tomography (A) and computed tomography (B) images showing the penile soft tissue mass with intense F-18 fluorodeoxyglucose uptake (arrows).", "width": 700, "height": 308, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [3, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "82bcc3f5-b3cd-4bb9-bc2d-2c3508c7e7ca", "label": "a", "points": [[1.4, 2.1], [1.4, 276.3], [353.1, 276.3], [353.1, 2.1]], "color": "yellow"}, {"id": "136df69a-8139-49d1-8eb3-a031d09ec546", "label": "b", "points": [[359.7, 4.3], [359.7, 274.1], [694.8, 274.1], [694.8, 4.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Transaxial", "start": 10, "end": 20, "id": 3}, {"text": "fused", "start": 21, "end": 26, "id": 4}, {"text": "positron", "start": 27, "end": 35, "id": 5}, {"text": "emission", "start": 36, "end": 44, "id": 6}, {"text": "tomographycomputed", "start": 45, "end": 63, "id": 7}, {"text": "tomography", "start": 64, "end": 74, "id": 8}, {"text": "(", "start": 75, "end": 76, "id": 9}, {"text": "A", "start": 76, "end": 77, "id": 10}, {"text": ")", "start": 77, "end": 78, "id": 11}, {"text": "and", "start": 79, "end": 82, "id": 12}, {"text": "computed", "start": 83, "end": 91, "id": 13}, {"text": "tomography", "start": 92, "end": 102, "id": 14}, {"text": "(", "start": 103, "end": 104, "id": 15}, {"text": "B", "start": 104, "end": 105, "id": 16}, {"text": ")", "start": 105, "end": 106, "id": 17}, {"text": "images", "start": 107, "end": 113, "id": 18}, {"text": "showing", "start": 114, "end": 121, "id": 19}, {"text": "the", "start": 122, "end": 125, "id": 20}, {"text": "penile", "start": 126, "end": 132, "id": 21}, {"text": "soft", "start": 133, "end": 137, "id": 22}, {"text": "tissue", "start": 138, "end": 144, "id": 23}, {"text": "mass", "start": 145, "end": 149, "id": 24}, {"text": "with", "start": 150, "end": 154, "id": 25}, {"text": "intense", "start": 155, "end": 162, "id": 26}, {"text": "F-18", "start": 163, "end": 167, "id": 27}, {"text": "fluorodeoxyglucose", "start": 168, "end": 186, "id": 28}, {"text": "uptake", "start": 187, "end": 193, "id": 29}, {"text": "(", "start": 194, "end": 195, "id": 30}, {"text": "arrows", "start": 195, "end": 201, "id": 31}, {"text": ")", "start": 201, "end": 202, "id": 32}, {"text": ".", "start": 202, "end": 203, "id": 33}]}
{"pdf_hash": "50c9fe9a02eb81f1765063e1f1e9c705d57ecc8e", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Chest computed tomography taken at admission. Spheroidal matter in the cavity of the right lung apex is shown (A). Bronchoscopic findings on days 6 (B) and 8 of hospitalization (C). Active bleeding from the right B 1 a and B 1 b is shown (B). In each bronchus, 7-mm spigots were placed using sutures for easy removal (C).", "width": 1182, "height": 358, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59], "c": [26, 27, 28, 29, 35, 36, 37, 38, 39, 40, 41, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76]}, "subfigures": [{"id": "87d04fc1-62e1-4a3e-9c29-c7d4300548b7", "label": "a", "points": [[0, 3.7], [0, 321.2], [517.2, 321.2], [517.2, 3.7]], "color": "yellow"}, {"id": "0877e7ea-c315-4cff-9967-8fa08cca2767", "label": "b", "points": [[526.6, 321.2], [526.6, 0], [849.6, 0], [849.6, 321.2]], "color": "cyan"}, {"id": "465e7b81-d2c1-46cf-8c2b-8d4223232a94", "label": "c", "points": [[860.8, 3.7], [860.8, 332.4], [1178.3, 332.4], [1178.3, 3.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Chest", "start": 10, "end": 15, "id": 3}, {"text": "computed", "start": 16, "end": 24, "id": 4}, {"text": "tomography", "start": 25, "end": 35, "id": 5}, {"text": "taken", "start": 36, "end": 41, "id": 6}, {"text": "at", "start": 42, "end": 44, "id": 7}, {"text": "admission", "start": 45, "end": 54, "id": 8}, {"text": ".", "start": 54, "end": 55, "id": 9}, {"text": "Spheroidal", "start": 56, "end": 66, "id": 10}, {"text": "matter", "start": 67, "end": 73, "id": 11}, {"text": "in", "start": 74, "end": 76, "id": 12}, {"text": "the", "start": 77, "end": 80, "id": 13}, {"text": "cavity", "start": 81, "end": 87, "id": 14}, {"text": "of", "start": 88, "end": 90, "id": 15}, {"text": "the", "start": 91, "end": 94, "id": 16}, {"text": "right", "start": 95, "end": 100, "id": 17}, {"text": "lung", "start": 101, "end": 105, "id": 18}, {"text": "apex", "start": 106, "end": 110, "id": 19}, {"text": "is", "start": 111, "end": 113, "id": 20}, {"text": "shown", "start": 114, "end": 119, "id": 21}, {"text": "(", "start": 120, "end": 121, "id": 22}, {"text": "A", "start": 121, "end": 122, "id": 23}, {"text": ")", "start": 122, "end": 123, "id": 24}, {"text": ".", "start": 123, "end": 124, "id": 25}, {"text": "Bronchoscopic", "start": 125, "end": 138, "id": 26}, {"text": "findings", "start": 139, "end": 147, "id": 27}, {"text": "on", "start": 148, "end": 150, "id": 28}, {"text": "days", "start": 151, "end": 155, "id": 29}, {"text": "6", "start": 156, "end": 157, "id": 30}, {"text": "(", "start": 158, "end": 159, "id": 31}, {"text": "B", "start": 159, "end": 160, "id": 32}, {"text": ")", "start": 160, "end": 161, "id": 33}, {"text": "and", "start": 162, "end": 165, "id": 34}, {"text": "8", "start": 166, "end": 167, "id": 35}, {"text": "of", "start": 168, "end": 170, "id": 36}, {"text": "hospitalization", "start": 171, "end": 186, "id": 37}, {"text": "(", "start": 187, "end": 188, "id": 38}, {"text": "C", "start": 188, "end": 189, "id": 39}, {"text": ")", "start": 189, "end": 190, "id": 40}, {"text": ".", "start": 190, "end": 191, "id": 41}, {"text": "Active", "start": 192, "end": 198, "id": 42}, {"text": "bleeding", "start": 199, "end": 207, "id": 43}, {"text": "from", "start": 208, "end": 212, "id": 44}, {"text": "the", "start": 213, "end": 216, "id": 45}, {"text": "right", "start": 217, "end": 222, "id": 46}, {"text": "B", "start": 223, "end": 224, "id": 47}, {"text": "1", "start": 225, "end": 226, "id": 48}, {"text": "a", "start": 227, "end": 228, "id": 49}, {"text": "and", "start": 229, "end": 232, "id": 50}, {"text": "B", "start": 233, "end": 234, "id": 51}, {"text": "1", "start": 235, "end": 236, "id": 52}, {"text": "b", "start": 237, "end": 238, "id": 53}, {"text": "is", "start": 239, "end": 241, "id": 54}, {"text": "shown", "start": 242, "end": 247, "id": 55}, {"text": "(", "start": 248, "end": 249, "id": 56}, {"text": "B", "start": 249, "end": 250, "id": 57}, {"text": ")", "start": 250, "end": 251, "id": 58}, {"text": ".", "start": 251, "end": 252, "id": 59}, {"text": "In", "start": 253, "end": 255, "id": 60}, {"text": "each", "start": 256, "end": 260, "id": 61}, {"text": "bronchus", "start": 261, "end": 269, "id": 62}, {"text": ",", "start": 269, "end": 270, "id": 63}, {"text": "7-mm", "start": 271, "end": 275, "id": 64}, {"text": "spigots", "start": 276, "end": 283, "id": 65}, {"text": "were", "start": 284, "end": 288, "id": 66}, {"text": "placed", "start": 289, "end": 295, "id": 67}, {"text": "using", "start": 296, "end": 301, "id": 68}, {"text": "sutures", "start": 302, "end": 309, "id": 69}, {"text": "for", "start": 310, "end": 313, "id": 70}, {"text": "easy", "start": 314, "end": 318, "id": 71}, {"text": "removal", "start": 319, "end": 326, "id": 72}, {"text": "(", "start": 327, "end": 328, "id": 73}, {"text": "C", "start": 328, "end": 329, "id": 74}, {"text": ")", "start": 329, "end": 330, "id": 75}, {"text": ".", "start": 330, "end": 331, "id": 76}]}
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Representative ultrastructural appearances of impaired lungs in normal group (a) and in blast injury groups at 10 cm (b, c), 15 cm (d\u2013f), 20 cm (g, h), and 30 cm (i). a: normal lung; b: swelling of pulmonary microvascular endothelial cells with nuclear swelling; c: necrosis of pulmonary microvascular endothelial cells; d: significantly widened gaps between pulmonary microvascular endothelial cells; e: red blood cells escaped through the alveolar wall; f: swelling observed in the pulmonary capillary endothelial cells and neutrophils incarcerated in the endovascular system; g and h: pulmonary capillary endothelial cell swelling; i: no cell swelling was observed.", "width": 1346, "height": 912, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 52, 53, 54, 55], "b": [3, 4, 5, 6, 7, 8, 16, 17, 18, 19, 20, 21, 22, 23, 24, 27, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67], "c": [3, 4, 5, 6, 7, 8, 16, 17, 18, 19, 20, 21, 22, 23, 26, 27, 69, 70, 71, 72, 73, 74, 75, 76], "d": [3, 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{"pdf_hash": "12f2a33aad6d468112996d2e124edfa4c76abe9a", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4 Clinical example of the signet ring cell carcinoma associated with infiltrative intramucosal spread. A: An endoscopic image of an EGC, showing a flat lesion located in the lesser curvature of the lower body (circle). Endoscopically, the surrounding mucosa exhibited atrophic gastritis; B: After endoscopic resection, three of the lateral margins were positive (circle); C: Pathological findings after endoscopic resection (\u00d7 40). Signet ring cell carcinoma cells exhibited subepithelial spread. In other words, the lesion was of the infiltrative type (circle). 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{"pdf_hash": "914f254849e71ece558cf582249787b8007e7c0f", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. A) T1-weighted magnetic resonance imaging in axial plane shows normal origin of coronary arteries, with coronary ostia (arrows), and the proximal portion of the left anterior descending and circumflex arteries. Descending aorta located on the right side. B) Threedimensional coronary MR angiography shows normal path of right coronary artery. C) Three-dimensional coronary MR angiography shows normal path of left anterior descending and circumflex arteries. 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{"pdf_hash": "519cacc770e2d075d3798fe190c0e08ede6cb157", "fig_key": "Figure2", "fig_uri": "8-Figure2-1.png", "text": "Fig 2. Immunohistochemical labeling of normal oral mucosa (A,D,G), oral leukoplakia (B,E,H) and oral squamous cell carcinoma (G,H,I) for MMP9 (A,B,C), BGH3 (D,E,F) and PDIA3 (G,H,I). Brown staining represents positive expression of proteins. MMP9 expression in stroma cells is low (A). Positive MMP9 cytoplasmic staining of basal cells in OLK (B). Strong nuclear and cytoplasmic MMP9 staining of OSCC (C). Negative BGH3 expression in NOM (D). Weak or moderate BGH3 staining of the basement membrane in OLK (E). Strong positive BGH3 expression in tumor basement membrane and extracellular skeletal stroma of OSCC (F). Negative PDIA3 staining in NOM (G). Moderate to strong PDIA3 staining in the cytoplasm and nucleus of OLK epithelium cells (H). 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{"pdf_hash": "8866fcd9d6541801acda84f1e84774e58f5be490", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 -AFM image of a typical Cryptosporidium parvum oocyst obtained in soft contact (electrical double layer and steric force) mode. The image was obtained with a sharpened silicon nitride cantilever at pH 8.5 and at 1 mM KNO 3 : (a) 3.4 lm scan, the total z-range of the figure is 1000 nm and the edge of a second oocyst can be observed in the top left corner of the image. (b) 1.25 lm scan showing the roughness of the oocyst surface. Reprinted with permission form Considine et al. (2001). 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{"pdf_hash": "de652f0b431f66d4ea86c783834dafbe2070e3b3", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Boundaries of retinal vascular plexuses and retinal layer segmentation. Optical coherence tomography B-scans with angio-flow showing the retinal segmentation in the different capillary plexuses (top and middle) and the segmentation of the retinal layers (bottom). A. B-scan showing the boundaries (red and green lines) that delineate the SVP between the ILM and 9 mm above the junction between the IPL-INL. B. B-scan showing the boundaries (green and red lines) that delineate the DVC between 9 mm above the IPL-INL junction and 9 mm below the OPL-ONL; there is no overlap between the 2 previous slabs. C. B-scan showing the boundaries (green and red lines) that delineate the ICP between 9 mm above the IPL-INL junction and 6 mm below the INL-OPL junction, thus including parts of the IPL and OPL and all the INL. D. Bscan showing the boundaries (red lines) that delineate the DCP between 6 mm below the INL-OPL junction and 9 mm below the OPL-ONL junction, thus including the OPL. E. Bscan showing the retinal layer segmentation provided by AngioAnalytic software. From the inner retina to the outer retina: white line (ILM), yellow line (outer boundary of the nerve fiber layer), orange line (outer boundary of the IPL), red line (outer boundary of the INL), violet line (outer boundary of the OPL), and purple line (outer boundary of the retinal pigment epithelium).", "width": 1044, "height": 1052, "subcaptions": {"a": [49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80], "b": [81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125], "c": [126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174], "d": [175, 176, 177, 178, 179, 180, 181, 182, 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{"pdf_hash": "cb90aa5275b758acc7b5c49900f0b235bc0b687c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Brain magnetic resonance imaging show diffuse astrocytoma in the anterior third ventricle and hypothalamus. Sagittal FLAIR image (A), T2-weighted axial image (B), and T1-weighted axial image after administration of gadolinium (C) show an ill-defined lesion with nodular enhancement, which involves the anterior third ventricle and bilateral hypothalamis (arrowhead). The images before treatment also show compression and inferiorly displacement of the midbrain including the substantia nigra by the tumor mass and obstructive hydrocephalus secondary to the tumor (arrow). The images after treatment with surgical excision and cerebrospinal fluid drainage show significant decrease of the tumor and lateral ventricles, and consequent improvement of midbrain compression (D, E and F). 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{"pdf_hash": "b62211c2a3acc7e14397cdb2ead6accdaaad7c22", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Group A (Top): maximum amount of remaining coronal dentin located at the gingival margin before (left column) and after (right column) post cementation and preparation design \u2013 no ferrule effect. Buccal view. Group B: maximum amount of remaining coronal dentin located below the half of the preparation height before (left column) and after (right column) post cementation and preparation design. Buccal view. 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{"pdf_hash": "5277a9ea1485ecb6e571ffe33a3298c720848b74", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1. CT head showing enlarged right frontal scalp mass. A: axial view non-contrast, B: axial view with contrast, C: Coronal view with contrast.", "width": 1358, "height": 530, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26], "c": [27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "54449f9a-e586-40eb-886f-a25fec9d86af", "label": "a", "points": [[2.1, 6.4], [2.1, 527.8], [411.9, 527.8], [411.9, 6.4]], "color": "yellow"}, {"id": "ae9031fd-a6a5-4624-b3f8-ce22a17be025", "label": "b", "points": [[435.5, 0], [435.5, 529.9], [826, 529.9], [826, 0]], "color": "cyan"}, {"id": "7acec5eb-f6af-4800-af95-29ae583360f2", "label": "c", "points": [[847.4, 4.3], [847.4, 529.9], [1349.4, 529.9], [1349.4, 4.3]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "head", "start": 13, "end": 17, "id": 4}, {"text": "showing", "start": 18, "end": 25, "id": 5}, {"text": "enlarged", "start": 26, "end": 34, "id": 6}, {"text": "right", "start": 35, "end": 40, "id": 7}, {"text": "frontal", "start": 41, "end": 48, "id": 8}, {"text": "scalp", "start": 49, "end": 54, "id": 9}, {"text": "mass", "start": 55, "end": 59, "id": 10}, {"text": ".", "start": 59, "end": 60, "id": 11}, {"text": "A", "start": 61, "end": 62, "id": 12}, {"text": ":", "start": 62, "end": 63, "id": 13}, {"text": "axial", "start": 64, "end": 69, "id": 14}, {"text": "view", "start": 70, "end": 74, "id": 15}, {"text": "non", "start": 75, "end": 78, "id": 16}, {"text": "-", "start": 78, "end": 79, "id": 17}, {"text": "contrast", "start": 79, "end": 87, "id": 18}, {"text": ",", "start": 87, "end": 88, "id": 19}, {"text": "B", "start": 89, "end": 90, "id": 20}, {"text": ":", "start": 90, "end": 91, "id": 21}, {"text": "axial", "start": 92, "end": 97, "id": 22}, {"text": "view", "start": 98, "end": 102, "id": 23}, {"text": "with", "start": 103, "end": 107, "id": 24}, {"text": "contrast", "start": 108, "end": 116, "id": 25}, {"text": ",", "start": 116, "end": 117, "id": 26}, {"text": "C", "start": 118, "end": 119, "id": 27}, {"text": ":", "start": 119, "end": 120, "id": 28}, {"text": "Coronal", "start": 121, "end": 128, "id": 29}, {"text": "view", "start": 129, "end": 133, "id": 30}, {"text": "with", "start": 134, "end": 138, "id": 31}, {"text": "contrast", "start": 139, "end": 147, "id": 32}, {"text": ".", "start": 147, "end": 148, "id": 33}]}
{"pdf_hash": "b5807e434fa59c81ae7a5fa429ca4d98e69d6903", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Scanning electron microscopic image of a control limbal segment with Schlemm\u2019s canal (SC) untouched by a microstent. Trabecular meshwork (TM) tissue was removed leaving only a rim of tissue at the margins of the SC external wall. Single arrow points to collector channels (CC). (A) Double arrow spans across the external wall of SC where the upper head of the double arrow contacts the residual rim of trabecular meshwork. (B) Magnification of region outlined in (A). (C) Dotted rectangles outline areas of elongated somewhat spindle-shaped elevations oriented circumferentially in SC consistent with the presence of nuclear profiles typical of an intact endothelium of SC external wall. (D) Collector channel entrance has one sharply demarcated edge and one sloping edge consistent with an oblique entry to SC. 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{"pdf_hash": "f2e2a107e59ae19b5879773fa993e38fd76f84e7", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2 - Juvenile nasopharyngeal angiofibroma, case P5, Radkowski grade 2c. Axial CT (A) and MRI T2-weighted scans (B) showing a mass in the dorsal two thirds of the left nasal cavity and in the sphenoid sinus (marked by S) with a bulky extension to the pterygopalatine fossa and the ITF. Extensive anteroposterior widening of the sphenopalatine foramen is marked by arrows. 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{"pdf_hash": "d4acea1f2bce87668ebad354caeef000b57766c1", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Radiograph images. (A) Anteroposterior (AP) radiograph of 31-year-old woman showed posterior dislocation with acetabular fracture. (B) Acetabular was reducted and fixed with recon-plate. (C) AP radiograph showed a total hip replacement arthroplasty state using 36-mm femoral head with highly cross-linked polyethylene. 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{"pdf_hash": "aa3768dfa6ea35ce746ffd282d163a65320f37fc", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Initial computed tomography (CT) and [18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET). (A) CT scan showed multiple nodules and edema in the bilateral cerebral hemispheres. (B) CT scan showed swelling of the mediastinal lymph nodes (arrowhead). (C) CT scan showed upper abdominal lymph node swelling (arrowhead). 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{"pdf_hash": "4cc72fa76714db2add04dcc3c7f0046fa510b9e9", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. A pretreatment multimodal imaging study of a 32-year-old Caucasian woman who presented with multifocal choroiditis with panuveitis (MCP) in her right eye. (A) Ultra-wide field color fundus image. (B) Fluorescein angiography (FA). (C) Indocyanine green angiography (ICGA). (D) Fundus autofluorescence (FAF) ultrawide field image. 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{"pdf_hash": "8012bf6110419f2ddfbe5503582da38fad87a7a0", "fig_key": "Figure14", "fig_uri": "16-Figure14-1.png", "text": "Figure 14. Lipoma in a 77-year-old man with a foreign body sensation, episodes of suffocation, and change in voice quality. (a) Axial contrast-enhanced CT scan obtained at the supraglottic level shows a homogeneous, nonenhancing lesion isoattenuating to fat at the level of the right aryepiglottic fold (arrowhead). (b) Endoscopic image demonstrates a pedunculated mass covered by intact laryngeal mucosa arising from the right aryepiglottic fold (arrowhead). (c) Low-power photomicrograph (original magnification, x25; hematoxylin-eosin stain) shows intact overlying squamous epithelium (arrows). Lobulated laryngeal lipoma composed of mature adipocytes (*) and a fibrous pseudocapsule (arrowheads) are also seen. 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{"pdf_hash": "6fcf23b55c54b6341a44a01e66b7624101ad7b27", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Transmission electron microscopy (TEM) to reveal lipid droplets on colorectal cells. (A\u2013F): TEM images of the CR-CSCs, their differentiated forms (SDACs), CCCs, and NECCs. (A and B), parasagittal sections of (A) CR-CSCs and (B) SDACs belonging to human patient 1; (C and D), parasagittal sections of (C) CR-CSCs and (D) SDACs belonging to human patient 2; (E), parasagittal section of a CCC; (F), parasagittal section of a NECC. White arrowheads point to mitochondria; black arrowheads point to multivesicular bodies and late-endosome/lysosome hybrids. LDs are colored in red. n, nucleus. (G): TEM image of a LD in cross-section. The asterisk points to the endoplasmic reticulum. Inset: detail of the LD single membrane leaflet. (H): Volume fraction of LDs in the cytoplasm and in the whole cell. Error bars, SEM. Statistical significance is denoted by * (p .01, Student\u2019s t test). Scale bars are 4 mm for A\u2013F and 100 nm for G. 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{"pdf_hash": "dad1c7bb696e962fb8a8764d4873ac870bd337c2", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. (a) Oblique sagittal reformatted view of the pelvis CT scan (bone window, slice thickness 1 mm) acquired after osteosynthesis (first step of the procedure). The first screw was placed into the iliac bone from the posterior iliac crest to the anterior inferior iliac spine along the arcuate line. The cross section of the proximal part of the second screw inserted into the sacroiliac joint is visible (small arrow). (b) Oblique axial reformatted view of the pelvis CT scan after iliac screw fixation. (c) Oblique axial reformatted view of the pelvis CT scan after sacral screw fixation. 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{"pdf_hash": "ab8fdd5efb890e5b8bf2eeb807820bf46ce64329", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. (a) an axial view through the Presage dosimeter at a plane through one of the 4 target points. (b) the same image but with central beam line annotations to highlight the cone misalignment.", "width": 794, "height": 378, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "f2e6edd8-f4c4-458d-8f3c-25cdb774eea9", "label": "a", "points": [[11.5, 5.4], [11.5, 376.7], [377.8, 376.7], [377.8, 5.4]], "color": "yellow"}, {"id": "ce6ec871-ca03-4001-8b40-bb88a7eaebae", "label": "b", "points": [[410.4, 11.7], [410.4, 376.7], [786.7, 376.7], [786.7, 11.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "an", "start": 14, "end": 16, "id": 6}, {"text": "axial", "start": 17, "end": 22, "id": 7}, {"text": "view", "start": 23, "end": 27, "id": 8}, {"text": "through", "start": 28, "end": 35, "id": 9}, {"text": "the", "start": 36, "end": 39, "id": 10}, {"text": "Presage", "start": 40, "end": 47, "id": 11}, {"text": "dosimeter", "start": 48, "end": 57, "id": 12}, {"text": "at", "start": 58, "end": 60, "id": 13}, {"text": "a", "start": 61, "end": 62, "id": 14}, {"text": "plane", "start": 63, "end": 68, "id": 15}, {"text": "through", "start": 69, "end": 76, "id": 16}, {"text": "one", "start": 77, "end": 80, "id": 17}, {"text": "of", "start": 81, "end": 83, "id": 18}, {"text": "the", "start": 84, "end": 87, "id": 19}, {"text": "4", "start": 88, "end": 89, "id": 20}, {"text": "target", "start": 90, "end": 96, "id": 21}, {"text": "points", "start": 97, "end": 103, "id": 22}, {"text": ".", "start": 103, "end": 104, "id": 23}, {"text": "(", "start": 105, "end": 106, "id": 24}, {"text": "b", "start": 106, "end": 107, "id": 25}, {"text": ")", "start": 107, "end": 108, "id": 26}, {"text": "the", "start": 109, "end": 112, "id": 27}, {"text": "same", "start": 113, "end": 117, "id": 28}, {"text": "image", "start": 118, "end": 123, "id": 29}, {"text": "but", "start": 124, "end": 127, "id": 30}, {"text": "with", "start": 128, "end": 132, "id": 31}, {"text": "central", "start": 133, "end": 140, "id": 32}, {"text": "beam", "start": 141, "end": 145, "id": 33}, {"text": "line", "start": 146, "end": 150, "id": 34}, {"text": "annotations", "start": 151, "end": 162, "id": 35}, {"text": "to", "start": 163, "end": 165, "id": 36}, {"text": "highlight", "start": 166, "end": 175, "id": 37}, {"text": "the", "start": 176, "end": 179, "id": 38}, {"text": "cone", "start": 180, "end": 184, "id": 39}, {"text": "misalignment", "start": 185, "end": 197, "id": 40}, {"text": ".", "start": 197, "end": 198, "id": 41}]}
{"pdf_hash": "3515cc32a25d3f982bb4f332413e0a5b60e5c68c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Preoperative sagittal (A) and axial (B) T2-weighted magnetic resonance images reveal a heterogeneous ventral intradural 2.5 cm diameter lesion in the C1-2 region. Sagittal T1-weighted images without enhancement (C) and with enhancement (D) reveal a well enhanced tumor with iso-signal intensity. The preoperative diagnosis was meningioma or schwannoma.", "width": 630, "height": 746, "subcaptions": {"a": [5, 6, 7, 8, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "c": [34, 35, 36, 37, 38, 39, 40, 41, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "d": [34, 35, 36, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "1378be66-49ca-41ec-a38d-571a152dacb4", "label": "a", "points": [[1, -0.3], [1, 354.7], [313, 354.7], [313, -0.3]], "color": "yellow"}, {"id": "0a14ae6b-3d4d-4352-90f8-b80c05af7159", "label": "b", "points": [[320, 2.7], [320, 351.7], [628, 351.7], [628, 2.7]], "color": "cyan"}, {"id": "52d0eaeb-9b36-461b-9b9c-88610fc0b30d", "label": "c", "points": [[3, 362.7], [3, 716.7], [312, 716.7], [312, 362.7]], "color": "magenta"}, {"id": "98e34bde-2656-4324-a026-56152d967b88", "label": "d", "points": [[316, 359.7], [316, 716.7], [628, 716.7], [628, 359.7]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Preoperative", "start": 8, "end": 20, "id": 4}, {"text": "sagittal", "start": 21, "end": 29, "id": 5}, {"text": "(", "start": 30, "end": 31, "id": 6}, {"text": "A", "start": 31, "end": 32, "id": 7}, {"text": ")", "start": 32, "end": 33, "id": 8}, {"text": "and", "start": 34, "end": 37, "id": 9}, {"text": "axial", "start": 38, "end": 43, "id": 10}, {"text": "(", "start": 44, "end": 45, "id": 11}, {"text": "B", "start": 45, "end": 46, "id": 12}, {"text": ")", "start": 46, "end": 47, "id": 13}, {"text": "T2-weighted", "start": 48, "end": 59, "id": 14}, {"text": "magnetic", "start": 60, "end": 68, "id": 15}, {"text": "resonance", "start": 69, "end": 78, "id": 16}, {"text": "images", "start": 79, "end": 85, "id": 17}, {"text": "reveal", "start": 86, "end": 92, "id": 18}, {"text": "a", "start": 93, "end": 94, "id": 19}, {"text": "heterogeneous", "start": 95, "end": 108, "id": 20}, {"text": "ventral", "start": 109, "end": 116, "id": 21}, {"text": "intradural", "start": 117, "end": 127, "id": 22}, {"text": "2.5", "start": 128, "end": 131, "id": 23}, {"text": "cm", "start": 132, "end": 134, "id": 24}, {"text": "diameter", "start": 135, "end": 143, "id": 25}, {"text": "lesion", "start": 144, "end": 150, "id": 26}, {"text": "in", "start": 151, "end": 153, "id": 27}, {"text": "the", "start": 154, "end": 157, "id": 28}, {"text": "C1", "start": 158, "end": 160, "id": 29}, {"text": "-", "start": 160, "end": 161, "id": 30}, {"text": "2", "start": 161, "end": 162, "id": 31}, {"text": "region", "start": 163, "end": 169, "id": 32}, {"text": ".", "start": 169, "end": 170, "id": 33}, {"text": "Sagittal", "start": 171, "end": 179, "id": 34}, {"text": "T1-weighted", "start": 180, "end": 191, "id": 35}, {"text": "images", "start": 192, "end": 198, "id": 36}, {"text": "without", "start": 199, "end": 206, "id": 37}, {"text": "enhancement", "start": 207, "end": 218, "id": 38}, {"text": "(", "start": 219, "end": 220, "id": 39}, {"text": "C", "start": 220, "end": 221, "id": 40}, {"text": ")", "start": 221, "end": 222, "id": 41}, {"text": "and", "start": 223, "end": 226, "id": 42}, {"text": "with", "start": 227, "end": 231, "id": 43}, {"text": "enhancement", "start": 232, "end": 243, "id": 44}, {"text": "(", "start": 244, "end": 245, "id": 45}, {"text": "D", "start": 245, "end": 246, "id": 46}, {"text": ")", "start": 246, "end": 247, "id": 47}, {"text": "reveal", "start": 248, "end": 254, "id": 48}, {"text": "a", "start": 255, "end": 256, "id": 49}, {"text": "well", "start": 257, "end": 261, "id": 50}, {"text": "enhanced", "start": 262, "end": 270, "id": 51}, {"text": "tumor", "start": 271, "end": 276, "id": 52}, {"text": "with", "start": 277, "end": 281, "id": 53}, {"text": "iso", "start": 282, "end": 285, "id": 54}, {"text": "-", "start": 285, "end": 286, "id": 55}, {"text": "signal", "start": 286, "end": 292, "id": 56}, {"text": "intensity", "start": 293, "end": 302, "id": 57}, {"text": ".", "start": 302, "end": 303, "id": 58}, {"text": "The", "start": 304, "end": 307, "id": 59}, {"text": "preoperative", "start": 308, "end": 320, "id": 60}, {"text": "diagnosis", "start": 321, "end": 330, "id": 61}, {"text": "was", "start": 331, "end": 334, "id": 62}, {"text": "meningioma", "start": 335, "end": 345, "id": 63}, {"text": "or", "start": 346, "end": 348, "id": 64}, {"text": "schwannoma", "start": 349, "end": 359, "id": 65}, {"text": ".", "start": 359, "end": 360, "id": 66}]}
{"pdf_hash": "494b632346c666f88c8de4722fbdde5fdd7aa019", "fig_key": "Figure9", "fig_uri": "10-Figure9-1.png", "text": "Fig. 9 MTX myelopathy. This 7-year-old female treated for ALL 2 years earlier, developed an isolated CNS relapse treated with cranial irradiation and five doses of IT MTX. She subsequently developed lower extremity paraparesis with urinary incontinence. Initial MR study of the spine was normal. a Sagittal T2-weighted noncontrast-enhanced image obtained after 2 weeks of persistent symptoms shows T2 hyperintensity along the dorsal aspect of the thoracic spinal cord (thick arrow). b\u2013e Sagittal T2-weighted", "width": 1372, "height": 994, "subcaptions": {"a": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83], "b": [84, 85, 86, 87, 88]}, "subfigures": [{"id": "00a5d108-63b1-4541-8e68-a506cd764d52", "label": "a", "points": [[1.2, 27.8], [1.2, 983.6], [308.9, 983.6], [308.9, 27.8]], "color": "yellow"}, {"id": "67c584ae-ba2f-4744-aa33-496fa9c85812", "label": "b", "points": [[293.8, 30], [293.8, 983.6], [603.7, 983.6], [603.7, 30]], "color": "cyan"}, {"id": "354cbdef-0a93-40d2-90d4-3fc7cc9a3d4d", "label": "b", "points": [[592.9, 38.7], [592.9, 970.6], [913.6, 970.6], [913.6, 38.7]], "color": "magenta"}, {"id": "de292c64-7750-4a09-9c73-56bb3c0869e7", "label": "b", 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WT (A), WT/mdx (C) and WT/mdx:utr (D) diaphragm muscle display sarcolemmadystrobrevin (green staining); mdx (B) and WT/mdx (C) diaphragm muscle display sarcolemma-utrophin (red staining); blue: nuclear staining (DAPI); magnification: 2006. doi:10.1371/journal.pone.0020065.g003", "width": 1008, "height": 744, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 10, 11, 12, 13, 30, 31], "b": [39, 40, 41, 42, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59], "c": [15, 16, 17, 18, 19, 20, 30, 31, 32, 33, 34, 35, 36, 37, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "40f91edf-10d0-4045-ba97-ca6e683e99d5", "label": "a", "points": [[16.7, 84.4], [16.7, 407.7], [499.2, 407.7], [499.2, 84.4]], "color": "yellow"}, {"id": "c7502637-3969-4263-9ca0-9e9b9119b030", "label": "c", "points": [[16.7, 417.2], [16.7, 732.5], [507.2, 732.5], [507.2, 417.2]], "color": "cyan"}, {"id": "8feba51e-a2a4-4b9f-9b8b-d37b3a7c27f7", "label": "d", "points": [[515.2, 414], [515.2, 738.9], 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{"pdf_hash": "4c7a14bc64958c7a865c2da61bfa24daac2b1572", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig 1. The mediolateral dimension of the synovial fold in the coronal plane was defined as the distance between lateral cortical margin of the radial head and free edge of the synovial fold (A). In addition, the mediolateral dimension of the radial head was measured using the greatest distance between medial and lateral cortical margins on the coronal images (B).", "width": 1220, "height": 786, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67]}, "subfigures": [{"id": "8b836acc-de9d-4431-b1d5-f9b011c1dc48", "label": "a", "points": [[10, 0.6], [10, 752.3], [607.4, 752.3], [607.4, 0.6]], "color": "yellow"}, {"id": "e02aa9d3-f94c-4d10-a837-4253b1c2e991", "label": "b", "points": [[640.2, 8.4], [640.2, 773.5], [1216.5, 773.5], [1216.5, 8.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "1", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "The", "start": 7, "end": 10, "id": 3}, {"text": "mediolateral", "start": 11, "end": 23, "id": 4}, {"text": "dimension", "start": 24, "end": 33, "id": 5}, {"text": "of", "start": 34, "end": 36, "id": 6}, {"text": "the", "start": 37, "end": 40, "id": 7}, {"text": "synovial", "start": 41, "end": 49, "id": 8}, {"text": "fold", "start": 50, "end": 54, "id": 9}, {"text": "in", "start": 55, "end": 57, "id": 10}, {"text": "the", "start": 58, "end": 61, "id": 11}, {"text": "coronal", "start": 62, "end": 69, "id": 12}, {"text": "plane", "start": 70, "end": 75, "id": 13}, {"text": "was", "start": 76, "end": 79, "id": 14}, {"text": "defined", "start": 80, "end": 87, "id": 15}, {"text": "as", "start": 88, "end": 90, "id": 16}, {"text": "the", "start": 91, "end": 94, "id": 17}, {"text": "distance", "start": 95, "end": 103, "id": 18}, {"text": "between", "start": 104, "end": 111, "id": 19}, {"text": "lateral", "start": 112, "end": 119, "id": 20}, {"text": "cortical", "start": 120, "end": 128, "id": 21}, {"text": "margin", "start": 129, "end": 135, "id": 22}, {"text": "of", "start": 136, "end": 138, "id": 23}, {"text": "the", "start": 139, "end": 142, "id": 24}, {"text": "radial", "start": 143, "end": 149, "id": 25}, {"text": "head", "start": 150, "end": 154, "id": 26}, {"text": "and", "start": 155, "end": 158, "id": 27}, {"text": "free", "start": 159, "end": 163, "id": 28}, {"text": "edge", "start": 164, "end": 168, "id": 29}, {"text": "of", "start": 169, "end": 171, "id": 30}, {"text": "the", "start": 172, "end": 175, "id": 31}, {"text": "synovial", "start": 176, "end": 184, "id": 32}, {"text": "fold", "start": 185, "end": 189, "id": 33}, {"text": "(", "start": 190, "end": 191, "id": 34}, {"text": "A", "start": 191, "end": 192, "id": 35}, {"text": ")", "start": 192, "end": 193, "id": 36}, {"text": ".", "start": 193, "end": 194, "id": 37}, {"text": "In", "start": 195, "end": 197, "id": 38}, {"text": "addition", "start": 198, "end": 206, "id": 39}, {"text": ",", "start": 206, "end": 207, "id": 40}, {"text": "the", "start": 208, "end": 211, "id": 41}, {"text": "mediolateral", "start": 212, "end": 224, "id": 42}, {"text": "dimension", "start": 225, "end": 234, "id": 43}, {"text": "of", "start": 235, "end": 237, "id": 44}, {"text": "the", "start": 238, "end": 241, "id": 45}, {"text": "radial", "start": 242, "end": 248, "id": 46}, {"text": "head", "start": 249, "end": 253, "id": 47}, {"text": "was", "start": 254, "end": 257, "id": 48}, {"text": "measured", "start": 258, "end": 266, "id": 49}, {"text": "using", "start": 267, "end": 272, "id": 50}, {"text": "the", "start": 273, "end": 276, "id": 51}, {"text": "greatest", "start": 277, "end": 285, "id": 52}, {"text": "distance", "start": 286, "end": 294, "id": 53}, {"text": "between", "start": 295, "end": 302, "id": 54}, {"text": "medial", "start": 303, "end": 309, "id": 55}, {"text": "and", "start": 310, "end": 313, "id": 56}, {"text": "lateral", "start": 314, "end": 321, "id": 57}, {"text": "cortical", "start": 322, "end": 330, "id": 58}, {"text": "margins", "start": 331, "end": 338, "id": 59}, {"text": "on", "start": 339, "end": 341, "id": 60}, {"text": "the", "start": 342, "end": 345, "id": 61}, {"text": "coronal", "start": 346, "end": 353, "id": 62}, {"text": "images", "start": 354, "end": 360, "id": 63}, {"text": "(", "start": 361, "end": 362, "id": 64}, {"text": "B", "start": 362, "end": 363, "id": 65}, {"text": ")", "start": 363, "end": 364, "id": 66}, {"text": ".", "start": 364, "end": 365, "id": 67}]}
{"pdf_hash": "c56133bb09610281a64f80f62cef28140c629f46", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. X-ray film of right foot in 16-year-old girl. Preoperative imaging (A) is compared with postoperative imaging at time of surgery (B) and at follow-up evaluation\u201426 years (C).", "width": 1234, "height": 374, "subcaptions": {"a": [16, 17, 18, 19, 20], "b": [32, 24, 25, 26, 27, 28, 29, 30, 31], "c": [34, 35, 36, 37, 38, 39, 40, 41, 42, 25]}, "subfigures": [{"id": "dbb42911-d87d-4388-9609-f82a57fb10e6", "label": "a", "points": [[39, 9.7], [39, 337.3], [403.5, 337.3], [403.5, 9.7]], "color": "yellow"}, {"id": "e194ca3d-41ec-461d-a0dd-b28fe6ab4d96", "label": "b", "points": [[413.3, 3.9], [413.3, 339.2], [803.2, 339.2], [803.2, 3.9]], "color": "cyan"}, {"id": "c239f09f-4ff5-4ea4-a113-fddd9666b798", "label": "c", "points": [[812.9, 7.8], [812.9, 339.2], [1183.3, 339.2], [1183.3, 7.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "X", "start": 10, "end": 11, "id": 3}, {"text": "-", "start": 11, "end": 12, "id": 4}, {"text": "ray", "start": 12, "end": 15, "id": 5}, {"text": "film", "start": 16, "end": 20, "id": 6}, {"text": "of", "start": 21, "end": 23, "id": 7}, {"text": "right", "start": 24, "end": 29, "id": 8}, {"text": "foot", "start": 30, "end": 34, "id": 9}, {"text": "in", "start": 35, "end": 37, "id": 10}, {"text": "16-year", "start": 38, "end": 45, "id": 11}, {"text": "-", "start": 45, "end": 46, "id": 12}, {"text": "old", "start": 46, "end": 49, "id": 13}, {"text": "girl", "start": 50, "end": 54, "id": 14}, {"text": ".", "start": 54, "end": 55, "id": 15}, {"text": "Preoperative", "start": 56, "end": 68, "id": 16}, {"text": "imaging", "start": 69, "end": 76, "id": 17}, {"text": "(", "start": 77, "end": 78, "id": 18}, {"text": "A", "start": 78, "end": 79, "id": 19}, {"text": ")", "start": 79, "end": 80, "id": 20}, {"text": "is", "start": 81, "end": 83, "id": 21}, {"text": "compared", "start": 84, "end": 92, "id": 22}, {"text": "with", "start": 93, "end": 97, "id": 23}, {"text": "postoperative", "start": 98, "end": 111, "id": 24}, {"text": "imaging", "start": 112, "end": 119, "id": 25}, {"text": "at", "start": 120, "end": 122, "id": 26}, {"text": "time", "start": 123, "end": 127, "id": 27}, {"text": "of", "start": 128, "end": 130, "id": 28}, {"text": "surgery", "start": 131, "end": 138, "id": 29}, {"text": "(", "start": 139, "end": 140, "id": 30}, {"text": "B", "start": 140, "end": 141, "id": 31}, {"text": ")", "start": 141, "end": 142, "id": 32}, {"text": "and", "start": 143, "end": 146, "id": 33}, {"text": "at", "start": 147, "end": 149, "id": 34}, {"text": "follow", "start": 150, "end": 156, "id": 35}, {"text": "-", "start": 156, "end": 157, "id": 36}, {"text": "up", "start": 157, "end": 159, "id": 37}, {"text": "evaluation\u201426", "start": 160, "end": 173, "id": 38}, {"text": "years", "start": 174, "end": 179, "id": 39}, {"text": "(", "start": 180, "end": 181, "id": 40}, {"text": "C", "start": 181, "end": 182, "id": 41}, {"text": ")", "start": 182, "end": 183, "id": 42}, {"text": ".", "start": 183, "end": 184, "id": 43}]}
{"pdf_hash": "4a5ce0cd21f788028a627cba8440d706195d880d", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Fig. 3. Sagittal (A) and axial CT (B) view of the lumbar spine showing the typical vacuum phenomenon and profound water-like calcification with sparing of the central nucleus pulposus. A B", "width": 632, "height": 458, "subcaptions": {"a": [4, 5, 6, 7, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "eab8bdce-4a9e-4fb0-8c95-05316122c597", "label": "a", "points": [[-0.3, 2.3], [-0.3, 425.3], [228.7, 425.3], [228.7, 2.3]], "color": "yellow"}, {"id": "8473e696-88a1-4dbb-986e-cd53cb4d0834", "label": "b", "points": [[242.7, 2.3], [242.7, 425.3], [626.7, 425.3], [626.7, 2.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Sagittal", "start": 8, "end": 16, "id": 4}, {"text": "(", "start": 17, "end": 18, "id": 5}, {"text": "A", "start": 18, "end": 19, "id": 6}, {"text": ")", "start": 19, "end": 20, "id": 7}, {"text": "and", "start": 21, "end": 24, "id": 8}, {"text": "axial", "start": 25, "end": 30, "id": 9}, {"text": "CT", "start": 31, "end": 33, "id": 10}, {"text": "(", "start": 34, "end": 35, "id": 11}, {"text": "B", "start": 35, "end": 36, "id": 12}, {"text": ")", "start": 36, "end": 37, "id": 13}, {"text": "view", "start": 38, "end": 42, "id": 14}, {"text": "of", "start": 43, "end": 45, "id": 15}, {"text": "the", "start": 46, "end": 49, "id": 16}, {"text": "lumbar", "start": 50, "end": 56, "id": 17}, {"text": "spine", "start": 57, "end": 62, "id": 18}, {"text": "showing", "start": 63, "end": 70, "id": 19}, {"text": "the", "start": 71, "end": 74, "id": 20}, {"text": "typical", "start": 75, "end": 82, "id": 21}, {"text": "vacuum", "start": 83, "end": 89, "id": 22}, {"text": "phenomenon", "start": 90, "end": 100, "id": 23}, {"text": "and", "start": 101, "end": 104, "id": 24}, {"text": "profound", "start": 105, "end": 113, "id": 25}, {"text": "water", "start": 114, "end": 119, "id": 26}, {"text": "-", "start": 119, "end": 120, "id": 27}, {"text": "like", "start": 120, "end": 124, "id": 28}, {"text": "calcification", "start": 125, "end": 138, "id": 29}, {"text": "with", "start": 139, "end": 143, "id": 30}, {"text": "sparing", "start": 144, "end": 151, "id": 31}, {"text": "of", "start": 152, "end": 154, "id": 32}, {"text": "the", "start": 155, "end": 158, "id": 33}, {"text": "central", "start": 159, "end": 166, "id": 34}, {"text": "nucleus", "start": 167, "end": 174, "id": 35}, {"text": "pulposus", "start": 175, "end": 183, "id": 36}, {"text": ".", "start": 183, "end": 184, "id": 37}, {"text": "A", "start": 185, "end": 186, "id": 38}, {"text": "B", "start": 187, "end": 188, "id": 39}]}
{"pdf_hash": "0368679f50cc5619db33efeffacdd475a652773d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 The true lumen (T) and superior mesenteric artery (SMA) were compressed by the expanded false lumen (F). a Sagittal slice, b axial slice at the level of bronchial bifurcation, and c axial slice at the level of the SMA. T true lumen, F false lumen", "width": 850, "height": 640, "subcaptions": {"a": [27, 28, 29, 30], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "c": [42, 43, 44, 45, 46, 47, 48, 49, 50]}, "subfigures": [{"id": "020ea795-7200-474d-b689-7bd2b8871131", "label": "b", "points": [[420.3, 28.2], [420.3, 316.9], [816.4, 316.9], [816.4, 28.2]], "color": "cyan"}, {"id": "5b8fa82a-34c9-4926-8fd5-cfbdf0b275ab", "label": "c", "points": [[816.4, 320.9], [816.4, 605.6], [416.3, 605.6], [416.3, 320.9]], "color": "magenta"}, {"id": "70a9032a-6bd7-4d56-bf88-670a93020175", "label": "a", "points": [[38.9, 22.8], [38.9, 609.6], [409.6, 609.6], [409.6, 22.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "The", "start": 7, "end": 10, "id": 3}, {"text": "true", "start": 11, "end": 15, "id": 4}, {"text": "lumen", "start": 16, "end": 21, "id": 5}, {"text": "(", "start": 22, "end": 23, "id": 6}, {"text": "T", "start": 23, "end": 24, "id": 7}, {"text": ")", "start": 24, "end": 25, "id": 8}, {"text": "and", "start": 26, "end": 29, "id": 9}, {"text": "superior", "start": 30, "end": 38, "id": 10}, {"text": "mesenteric", "start": 39, "end": 49, "id": 11}, {"text": "artery", "start": 50, "end": 56, "id": 12}, {"text": "(", "start": 57, "end": 58, "id": 13}, {"text": "SMA", "start": 58, "end": 61, "id": 14}, {"text": ")", "start": 61, "end": 62, "id": 15}, {"text": "were", "start": 63, "end": 67, "id": 16}, {"text": "compressed", "start": 68, "end": 78, "id": 17}, {"text": "by", "start": 79, "end": 81, "id": 18}, {"text": "the", "start": 82, "end": 85, "id": 19}, {"text": "expanded", "start": 86, "end": 94, "id": 20}, {"text": "false", "start": 95, "end": 100, "id": 21}, {"text": "lumen", "start": 101, "end": 106, "id": 22}, {"text": "(", "start": 107, "end": 108, "id": 23}, {"text": "F", "start": 108, "end": 109, "id": 24}, {"text": ")", "start": 109, "end": 110, "id": 25}, {"text": ".", "start": 110, "end": 111, "id": 26}, {"text": "a", "start": 112, "end": 113, "id": 27}, {"text": "Sagittal", "start": 114, "end": 122, "id": 28}, {"text": "slice", "start": 123, "end": 128, "id": 29}, {"text": ",", "start": 128, "end": 129, "id": 30}, {"text": "b", "start": 130, "end": 131, "id": 31}, {"text": "axial", "start": 132, "end": 137, "id": 32}, {"text": "slice", "start": 138, "end": 143, "id": 33}, {"text": "at", "start": 144, "end": 146, "id": 34}, {"text": "the", "start": 147, "end": 150, "id": 35}, {"text": "level", "start": 151, "end": 156, "id": 36}, {"text": "of", "start": 157, "end": 159, "id": 37}, {"text": "bronchial", "start": 160, "end": 169, "id": 38}, {"text": "bifurcation", "start": 170, "end": 181, "id": 39}, {"text": ",", "start": 181, "end": 182, "id": 40}, {"text": "and", "start": 183, "end": 186, "id": 41}, {"text": "c", "start": 187, "end": 188, "id": 42}, {"text": "axial", "start": 189, "end": 194, "id": 43}, {"text": "slice", "start": 195, "end": 200, "id": 44}, {"text": "at", "start": 201, "end": 203, "id": 45}, {"text": "the", "start": 204, "end": 207, "id": 46}, {"text": "level", "start": 208, "end": 213, "id": 47}, {"text": "of", "start": 214, "end": 216, "id": 48}, {"text": "the", "start": 217, "end": 220, "id": 49}, {"text": "SMA", "start": 221, "end": 224, "id": 50}, {"text": ".", "start": 224, "end": 225, "id": 51}, {"text": "T", "start": 226, "end": 227, "id": 52}, {"text": "true", "start": 228, "end": 232, "id": 53}, {"text": "lumen", "start": 233, "end": 238, "id": 54}, {"text": ",", "start": 238, "end": 239, "id": 55}, {"text": "F", "start": 240, "end": 241, "id": 56}, {"text": "false", "start": 242, "end": 247, "id": 57}, {"text": "lumen", "start": 248, "end": 253, "id": 58}]}
{"pdf_hash": "b9761942d6fbb2929a3e99d1c0c30136ab37fc17", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. MRI of both temporal bones performed 18 days before cochlear implantation. a T1-weighted image. A hyperintense lesion was seen in the basal turn of both cochleae (arrows). b , c Postcontrast T1-weighted images. An enhancing lesion was seen in the basal turn of the right cochlea ( b ; arrow) and in the vestibule of the right ear ( c ; arrow). d T1-weighted image. 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{"pdf_hash": "e4fa837ffcce0939068cb24a3435d1e62432158c", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Photomicrographs of hematoxylin and eosin stained chicken spleen section. (A) shows the normal histological structure of control group; (B) shows that congestion of red pulp (*) is obvious in 100% group. 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{"pdf_hash": "0bbccf7ce7df39c541c3cd516332861c0be6db7f", "fig_key": "Figure5", "fig_uri": "9-Figure5-1.png", "text": "FIGURE 5 | In vivo and in vitro bioluminescence emission by Y. ruckeri acrR \u2212 and acrR + strains. (A) Fish imaged at 4 days post infection carried out by intraperitoneal injection with the acrR \u2212 strain. Bioluminescence imaging of acrR \u2212 (B) and acrR + (C) strains in presence of different fish tissues deposited on TSA plates previously inoculated with the corresponding strain. Brain (1), heart (2), liver (3), spleen (4), adipose tissue (5), gut (6), gills (7). 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{"pdf_hash": "356ae7bafa64fa91ecf437c62bd0a7614319d92c", "fig_key": "Figure5", "fig_uri": "8-Figure5-1.png", "text": "Fig. 5 PCNA and OCT-4 expression in bilaterally ovariectomized mouse endometrial section. a, b. PCNA expression was minimal in the epithelial cells lining the lumen and the glands. Stromal cells did not express PCNA. Please note that few cells show relatively intense expression compared to others (arrow). c, d. OCT-4 expression was cytoplasmic in nature however; few spherical cells (arrow) expressed nuclear OCT-4A. Thus the OCT-4 antibody used in the present study helps to clearly delineate the two alternatively spliced isoforms of OCT-4 including nuclear OCT-4A and cytoplasmic OCT-4B. 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{"pdf_hash": "561e8d00d77ea1169b6607ea0f0f3de5d8bfc85d", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3: Examples of the performance of different tools on the occipital lobe on a T1 scan. (A) The T1 scan without a segmentation. (B) The T1 scan with an example of a good regional delineation (MALP-EM). (C) The T1 scan with an example of a poor occipital lobe delineation with spillage into the dura in the medial section of the region (SPM 8 Unified Segment). (D) The T1 scan with an example of a poor occipital lobe delineation with spillage into the dura in the medial and superior sections of the region (SPM 8 New Segment). (E) The T1 scan with an example of a poor occipital lobe delineation with spillage into the dura in the medial and superior sections of the region (FSL FAST). The scans are viewed in FSLeyes with the T1 scan as a base image, and the GM region as an overlay. In this figure, the GM regions are viewed as red-yellow with an opacity of 0.4. 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{"pdf_hash": "13f70983037f4c5c4386a277d4ef4f76ea122663", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig 2 High resolution computed tomograms of two patients whose chest radiographs were normal: (above) ground glass opacification in the posterior segments of the left lower lobe (difficult to identify on a frontal chest radiograph because of location behind the heart); (below) ground glass opacification in the posterior segments of the right lower lobe (difficult to identify on a frontal chest radiograph because of location behind the diaphragm)", "width": 558, "height": 808, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "b": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77]}, "subfigures": [{"id": "27f5c44c-6c3a-4d25-86f1-cff5fb5ec56d", "label": "a", "points": [[0.8, 4.9], [0.8, 423.9], 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{"pdf_hash": "48dc5ceabd11f52186638e092a43a81cc9a7ec19", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. A CMB detected with SWI with postmortem 3T MRI (A) is compared with HE staining of the brain block (B) of subject C1. The rectangle in B is enlarged in C and shows accumulation of hemosiderin-laden macrophages around the small vessels (Inset). Scale bars in C: 200 m (inset: 20 m).", "width": 868, "height": 324, "subcaptions": {"a": [32, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 29, 30, 31], "b": [32, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "6aeb6cf8-fefa-4968-8981-0ee5fe3c8c8a", "label": "a", "points": [[3.4, 1.4], [3.4, 139.9], [435.4, 139.9], [435.4, 1.4]], "color": "yellow"}, {"id": "8597db83-6247-47e6-a379-0ae4e43cf51a", "label": "b", "points": [[7.5, 145.4], [7.5, 319.5], [432.7, 319.5], [432.7, 145.4]], "color": "cyan"}, {"id": "25afa797-ba1f-4196-81fa-2bd6cdc5aa81", "label": "c", "points": [[439.5, 2.7], [439.5, 316.8], [863.3, 316.8], [863.3, 2.7]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": "CMB", "start": 10, "end": 13, "id": 5}, {"text": "detected", "start": 14, "end": 22, "id": 6}, {"text": "with", "start": 23, "end": 27, "id": 7}, {"text": "SWI", "start": 28, "end": 31, "id": 8}, {"text": "with", "start": 32, "end": 36, "id": 9}, {"text": "postmortem", "start": 37, "end": 47, "id": 10}, {"text": "3", "start": 48, "end": 49, "id": 11}, {"text": "T", "start": 49, "end": 50, "id": 12}, {"text": "MRI", "start": 51, "end": 54, "id": 13}, {"text": "(", "start": 55, "end": 56, "id": 14}, {"text": "A", "start": 56, "end": 57, "id": 15}, {"text": ")", "start": 57, "end": 58, "id": 16}, {"text": "is", "start": 59, "end": 61, "id": 17}, {"text": "compared", "start": 62, "end": 70, "id": 18}, {"text": "with", "start": 71, "end": 75, "id": 19}, {"text": "HE", "start": 76, "end": 78, "id": 20}, {"text": "staining", "start": 79, "end": 87, "id": 21}, {"text": "of", "start": 88, "end": 90, "id": 22}, {"text": "the", "start": 91, "end": 94, "id": 23}, {"text": "brain", "start": 95, "end": 100, "id": 24}, {"text": "block", "start": 101, "end": 106, "id": 25}, {"text": "(", "start": 107, "end": 108, "id": 26}, {"text": "B", "start": 108, "end": 109, "id": 27}, {"text": ")", "start": 109, "end": 110, "id": 28}, {"text": "of", "start": 111, "end": 113, "id": 29}, {"text": "subject", "start": 114, "end": 121, "id": 30}, {"text": "C1", "start": 122, "end": 124, "id": 31}, {"text": ".", "start": 124, "end": 125, "id": 32}, {"text": "The", "start": 126, "end": 129, "id": 33}, {"text": "rectangle", "start": 130, "end": 139, "id": 34}, {"text": "in", "start": 140, "end": 142, "id": 35}, {"text": "B", "start": 143, "end": 144, "id": 36}, {"text": "is", "start": 145, "end": 147, "id": 37}, {"text": "enlarged", "start": 148, "end": 156, "id": 38}, {"text": "in", "start": 157, "end": 159, "id": 39}, {"text": "C", "start": 160, "end": 161, "id": 40}, {"text": "and", "start": 162, "end": 165, "id": 41}, {"text": "shows", "start": 166, "end": 171, "id": 42}, {"text": "accumulation", "start": 172, "end": 184, "id": 43}, {"text": "of", "start": 185, "end": 187, "id": 44}, {"text": "hemosiderin", "start": 188, "end": 199, "id": 45}, {"text": "-", "start": 199, "end": 200, "id": 46}, {"text": "laden", "start": 200, "end": 205, "id": 47}, {"text": "macrophages", "start": 206, "end": 217, "id": 48}, {"text": "around", "start": 218, "end": 224, "id": 49}, {"text": "the", "start": 225, "end": 228, "id": 50}, {"text": "small", "start": 229, "end": 234, "id": 51}, {"text": "vessels", "start": 235, "end": 242, "id": 52}, {"text": "(", "start": 243, "end": 244, "id": 53}, {"text": "Inset", "start": 244, "end": 249, "id": 54}, {"text": ")", "start": 249, "end": 250, "id": 55}, {"text": ".", "start": 250, "end": 251, "id": 56}, {"text": "Scale", "start": 252, "end": 257, "id": 57}, {"text": "bars", "start": 258, "end": 262, "id": 58}, {"text": "in", "start": 263, "end": 265, "id": 59}, {"text": "C", "start": 266, "end": 267, "id": 60}, {"text": ":", "start": 267, "end": 268, "id": 61}, {"text": "200", "start": 269, "end": 272, "id": 62}, {"text": "m", "start": 273, "end": 274, "id": 63}, {"text": "(", "start": 275, "end": 276, "id": 64}, {"text": "inset", "start": 276, "end": 281, "id": 65}, {"text": ":", "start": 281, "end": 282, "id": 66}, {"text": "20", "start": 283, "end": 285, "id": 67}, {"text": "m", "start": 286, "end": 287, "id": 68}, {"text": ")", "start": 287, "end": 288, "id": 69}, {"text": ".", "start": 288, "end": 289, "id": 70}]}
{"pdf_hash": "80d104184c3ef98e9a4566be2d7ce84d87662e4b", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "FIG. 5. EBNA-1 coexpression results in the increased nuclear accumulation of epitope-tagged p32(74-282). HeLa cells were cotransfected with pE1A-CMX/p32(74-282) and pCMX (A and B), pCMX/EBNA-1 (C and D), pCMX/EBNA-1\u232cgly-ala (E and F), pCMX/EBNA-1\u232cBox A (G and H), pCMX/EBNA-1\u232cBox B/C (I and J), or pCMX/EBNA-1\u232cBox A/B/C (K and L) and IF stains were performed 48 h later with mAb M45 to detect epitope-tagged p32(74-282) and an anti-EBNA-1 serum. Primary antibodies were detected with FITC-conjugated goat anti-mouse IgG and TRITC-conjugated goat anti-rabbit IgG. A and B show labeling of M45-p32(74-282) in two different fields of cells. 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{"pdf_hash": "f3a1542d898c981d7688b911b7fbefc8cc5e3e71", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 a Combined failure after insufficient correction of sagittal misaligment (improper distal foundation without pelvic fixation and inadequate lordosis). Failure with pullout at S1 and rod breakage. b Revision surgery with extension of fixation to pelvis, multiple SPOs to increase lordosis at L2\u2013L3\u2013L4 and anterior column reconstruction with XLIF at L3\u2013L4\u2013L5 and PLIF at L5\u2013S1", "width": 1016, "height": 644, "subcaptions": {"a": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "46f2f5b9-8552-4a8d-a23f-4cba2ebc7ead", "label": "a", "points": [[11.5, 8.6], [11.5, 642.6], [374.2, 642.6], [374.2, 8.6]], "color": "yellow"}, {"id": "69208522-da04-4c4a-b013-33deabb0cdc8", "label": "a", "points": [[390.3, 10.2], [390.3, 642.6], [817.2, 642.6], [817.2, 10.2]], "color": "cyan"}, {"id": "9af56c59-b9fb-41a3-bfe4-412e3d0d8ac2", "label": "b", "points": [[828.5, 8.6], [828.5, 642.6], [1013.1, 642.6], [1013.1, 8.6]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Combined", "start": 9, "end": 17, "id": 4}, {"text": "failure", "start": 18, "end": 25, "id": 5}, {"text": "after", "start": 26, "end": 31, "id": 6}, {"text": "insufficient", "start": 32, "end": 44, "id": 7}, {"text": "correction", "start": 45, "end": 55, "id": 8}, {"text": "of", "start": 56, "end": 58, "id": 9}, {"text": "sagittal", "start": 59, "end": 67, "id": 10}, {"text": "misaligment", "start": 68, "end": 79, "id": 11}, {"text": "(", "start": 80, "end": 81, "id": 12}, {"text": "improper", "start": 81, "end": 89, "id": 13}, {"text": "distal", "start": 90, "end": 96, "id": 14}, {"text": "foundation", "start": 97, "end": 107, "id": 15}, {"text": "without", "start": 108, "end": 115, "id": 16}, {"text": "pelvic", "start": 116, "end": 122, "id": 17}, {"text": "fixation", "start": 123, "end": 131, "id": 18}, {"text": "and", "start": 132, "end": 135, "id": 19}, {"text": "inadequate", "start": 136, "end": 146, "id": 20}, {"text": "lordosis", "start": 147, "end": 155, "id": 21}, {"text": ")", "start": 155, "end": 156, "id": 22}, {"text": ".", "start": 156, "end": 157, "id": 23}, {"text": "Failure", "start": 158, "end": 165, "id": 24}, {"text": "with", "start": 166, "end": 170, "id": 25}, {"text": "pullout", "start": 171, "end": 178, "id": 26}, {"text": "at", "start": 179, "end": 181, "id": 27}, {"text": "S1", "start": 182, "end": 184, "id": 28}, {"text": "and", "start": 185, "end": 188, "id": 29}, {"text": "rod", "start": 189, "end": 192, "id": 30}, {"text": "breakage", "start": 193, "end": 201, "id": 31}, {"text": ".", "start": 201, "end": 202, "id": 32}, {"text": "b", "start": 203, "end": 204, "id": 33}, {"text": "Revision", "start": 205, "end": 213, "id": 34}, {"text": "surgery", "start": 214, "end": 221, "id": 35}, {"text": "with", "start": 222, "end": 226, "id": 36}, {"text": "extension", "start": 227, "end": 236, "id": 37}, {"text": "of", "start": 237, "end": 239, "id": 38}, {"text": "fixation", "start": 240, "end": 248, "id": 39}, {"text": "to", "start": 249, "end": 251, "id": 40}, {"text": "pelvis", "start": 252, "end": 258, "id": 41}, {"text": ",", "start": 258, "end": 259, "id": 42}, {"text": "multiple", "start": 260, "end": 268, "id": 43}, {"text": "SPOs", "start": 269, "end": 273, "id": 44}, {"text": "to", "start": 274, "end": 276, "id": 45}, {"text": "increase", "start": 277, "end": 285, "id": 46}, {"text": "lordosis", "start": 286, "end": 294, "id": 47}, {"text": "at", "start": 295, "end": 297, "id": 48}, {"text": "L2\u2013L3\u2013L4", "start": 298, "end": 306, "id": 49}, {"text": "and", "start": 307, "end": 310, "id": 50}, {"text": "anterior", "start": 311, "end": 319, "id": 51}, {"text": "column", "start": 320, "end": 326, "id": 52}, {"text": "reconstruction", "start": 327, "end": 341, "id": 53}, {"text": "with", "start": 342, "end": 346, "id": 54}, {"text": "XLIF", "start": 347, "end": 351, "id": 55}, {"text": "at", "start": 352, "end": 354, "id": 56}, {"text": "L3\u2013L4\u2013L5", "start": 355, "end": 363, "id": 57}, {"text": "and", "start": 364, "end": 367, "id": 58}, {"text": "PLIF", "start": 368, "end": 372, "id": 59}, {"text": "at", "start": 373, "end": 375, "id": 60}, {"text": "L5\u2013S1", "start": 376, "end": 381, "id": 61}]}
{"pdf_hash": "244d4218dd971a206319803705dc66df7ebc9fc4", "fig_key": "Figure7", "fig_uri": "8-Figure7-1.png", "text": "FIG. 7. No obvious structures demarcate the pathways taken by growth cones extending towards the fin bud. Cross sections of the 57-hr embryo with diI-labeled growth cones shown in Fig. 6C and 6D. (A) Section showing labeled axons in the S2 nerve approximately 5 pm posterior to the most distal growth cones S, spinal cord; N, notochord; Ax, axial muscles; B, blood vessel; P, pronephros; F, fin bud. (B) Section at the level of the most distal growth cones and filopodia (arrowheads). (C) Section approximately 5 pm anterior to the most distal S2 growth cones. 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{"pdf_hash": "00e76b3c1fcdf31f6b440bda7865afa253cc1bcd", "fig_key": "Figure3", "fig_uri": "12-Figure3-1.png", "text": "Figure 3. Micro-CT graphs of Palaeonummulites venosus (upper row) and Operculina ammonoides (lower row). a micrograph showing all chambers; b equatorial section; c axial section cutting the final chamber; d areas of shell lumina in axial section.", "width": 1210, "height": 858, "subcaptions": {"a": [22, 23, 24, 25, 26], "b": [28, 29, 30], "c": [32, 33, 34, 35, 36, 37, 38], "d": [40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "0b1b73e7-b24c-4be8-95e7-3b85cd060c0d", "label": "a", "points": [[2.9, 3.8], [2.9, 854.5], [411.9, 854.5], [411.9, 3.8]], "color": "yellow"}, {"id": "02feb33b-8207-4ca2-a93a-34d09b470ffa", "label": "b", "points": [[427.2, 3.8], [427.2, 856.4], [763.7, 856.4], [763.7, 3.8]], "color": "cyan"}, {"id": "c8b000d7-43f2-45ae-bdab-1025a05029e3", "label": "c", "points": [[771.3, 5.7], [771.3, 852.6], [998.8, 852.6], [998.8, 5.7]], "color": "magenta"}, {"id": "311e8989-be23-4733-9599-1004d479f8ea", "label": "d", "points": [[1010.3, 7.6], [1010.3, 841.1], [1205.3, 841.1], [1205.3, 7.6]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Micro", "start": 10, "end": 15, "id": 3}, {"text": "-", "start": 15, "end": 16, "id": 4}, {"text": "CT", "start": 16, "end": 18, "id": 5}, {"text": "graphs", "start": 19, "end": 25, "id": 6}, {"text": "of", "start": 26, "end": 28, "id": 7}, {"text": "Palaeonummulites", "start": 29, "end": 45, "id": 8}, {"text": "venosus", "start": 46, "end": 53, "id": 9}, {"text": "(", "start": 54, "end": 55, "id": 10}, {"text": "upper", "start": 55, "end": 60, "id": 11}, {"text": "row", "start": 61, "end": 64, "id": 12}, {"text": ")", "start": 64, "end": 65, "id": 13}, {"text": "and", "start": 66, "end": 69, "id": 14}, {"text": "Operculina", "start": 70, "end": 80, "id": 15}, {"text": "ammonoides", "start": 81, "end": 91, "id": 16}, {"text": "(", "start": 92, "end": 93, "id": 17}, {"text": "lower", "start": 93, "end": 98, "id": 18}, {"text": "row", "start": 99, "end": 102, "id": 19}, {"text": ")", "start": 102, "end": 103, "id": 20}, {"text": ".", "start": 103, "end": 104, "id": 21}, {"text": "a", "start": 105, "end": 106, "id": 22}, {"text": "micrograph", "start": 107, "end": 117, "id": 23}, {"text": "showing", "start": 118, "end": 125, "id": 24}, {"text": "all", "start": 126, "end": 129, "id": 25}, {"text": "chambers", "start": 130, "end": 138, "id": 26}, {"text": ";", "start": 138, "end": 139, "id": 27}, {"text": "b", "start": 140, "end": 141, "id": 28}, {"text": "equatorial", "start": 142, "end": 152, "id": 29}, {"text": "section", "start": 153, "end": 160, "id": 30}, {"text": ";", "start": 160, "end": 161, "id": 31}, {"text": "c", "start": 162, "end": 163, "id": 32}, {"text": "axial", "start": 164, "end": 169, "id": 33}, {"text": "section", "start": 170, "end": 177, "id": 34}, {"text": "cutting", "start": 178, "end": 185, "id": 35}, {"text": "the", "start": 186, "end": 189, "id": 36}, {"text": "final", "start": 190, "end": 195, "id": 37}, {"text": "chamber", "start": 196, "end": 203, "id": 38}, {"text": ";", "start": 203, "end": 204, "id": 39}, {"text": "d", "start": 205, "end": 206, "id": 40}, {"text": "areas", "start": 207, "end": 212, "id": 41}, {"text": "of", "start": 213, "end": 215, "id": 42}, {"text": "shell", "start": 216, "end": 221, "id": 43}, {"text": "lumina", "start": 222, "end": 228, "id": 44}, {"text": "in", "start": 229, "end": 231, "id": 45}, {"text": "axial", "start": 232, "end": 237, "id": 46}, {"text": "section", "start": 238, "end": 245, "id": 47}, {"text": ".", "start": 245, "end": 246, "id": 48}]}
{"pdf_hash": "18a0a68860974fa2e0ed86810a27d48193e09048", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2: (a) Preoperative radiograph of right mandibular first molar with immature apices and necrotic pulp and apical radiolucencies. (b) Postoperative radiograph after root canal disinfection, treated dentin matrix fabrication, bleeding induction, and placement of calcium-enriched mixture cement over the blood clot. (c) Follow-up radiograph 6-month postoperation. 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{"pdf_hash": "24b71082377ad337e35ad35971bbfcd0cab583fd", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Brain MRI of the proband (A, B) and his nephew (C, D). (A) The T2 weighted image of the proband show bilateral striatal hyperintensities with necrosis. (B) The T1 weighted image of the proband show bilateral hypointensities with necrosis. (C) The T2 weighted image of his nephew shows bilateral putaminal hyperintensities without necrosis. 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{"pdf_hash": "4ff65eb0d6e6c57c689059418d7dcb04bec09538", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5. Group analysis of sign. (Upper half) SPMs of average neural activity within each group, deaf on the left and hearing on the right, during the sign-word discrimination and non-discrimination tasks compared with the rest period. The same format and statistical thresholds are used as in Figure 2. (Lower half) There was more prominent activation in the left PT in deaf subjects than in hearing subjects during the sign-word discrimination/non-discrimination tasks. The focus of activation on a pseudocolor fMRI is superimposed on a high-resolution anatomical MRI in the sagittal (upper left), coronal (upper right) and transaxial (lower left) planes, as indicated by the blue lines that cross at (--62, --20, 4) corresponding to the left PT (Brodmann area 42). The significance level of the activity is indicated by the color bar; this increases as red proceeds to white. The statistical threshold was P \\ 0.05, corrected for multiple comparisons at the cluster level. Lower right, percent signal change in the left PT (-- 62, --20, 4) of the deaf (open square) and hearing (closed square) during worddiscrimination and non-discrimination tasks, CLOSED, OPEN and O--C. *, ** and \u00fe indicate P\\ 0.001 (two-sample t-test), \u00fe\u00fe P 5 0.002 (two-sample t-test), 3 P 5 0.004 and 33 P\\ 0.001 (one-sample t-test).", "width": 678, "height": 1082, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "b": [61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92], "c": [93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 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{"pdf_hash": "4234e5e3cddddfb8a1d8035089f24e6da3d54545", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2: 63 year old female with gastric infarction. (a) Axial contrast-enhanced CT image demonstrates a distended stomach with gastric pneumatosis (red arrow). A moderate amount of perigastric fluid is noted (red arrowheads). (b) Coronal contrastenhanced CT image demonstrates a distended stomach with gastric pneumatosis (red arrow). Dilated small bowel loops (red open arrows), and a moderate amount of perigastric fluid (red arrowheads) are noted. (c) Sagittal contrast-enhanced CT image demonstrates a distended stomach with gastric pneumatosis (red arrow). Dilated small bowel loops with air-fluid levels (red open arrows) and a moderate amount of perigastric fluid (red arrowheads) are noted. 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{"pdf_hash": "4a83cf2bc8a8de6867717507165e5aa7990455df", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Axial (T2 weighted; a) and sagittal (T1 weighted; b) MRI image after 3 weeks epidural block through the interlaminar approach at L4\u2013L5. Hyperintense mass on T1\u2011weighted (white arrow) pushing on anterior aspect of the spinal cord at the L5\u2011S1 level (white arrow: epidural hematoma). Axial (T2 weighted; c) and sagittal (T1 weighted; d) MRI image after 10 months. The figure shows complete resolution of the hematoma shown in the previous images. 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{"pdf_hash": "a28f939f146b69624493d55bcd4c509fed5b9dea", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A: Annular measurement by cardiac computed tomography scan. The aortic annular size was 17.7 mm in area and 17.9 mm in circumference. B: Three-dimensional CT scan showing the relationship between the thoracotomy and the aortic root, and the difference between the thoracotomies. MIAVR is usually performed from the third intercostal space, so that the aortic valve, the aortotomy and the thoracotomy are located along a straight line. However, in the present case, surgery was performed through a right anterolateral thoracotomy at the fourth intercostal space in consideration of the access to the aortic root. 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{"pdf_hash": "584154ff9c088413dc7f0ba2d28b5e2ebf58ecf3", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. Discrepancy of capsule appearance assessment between readers. Axial contrast-enhanced MRI images in the delayed phase from a 57-year-old man (A) and a 66-year-old woman (B). Axial contrast-enhanced CT images also in the delayed phase from a 64-year-old man (C) and a 68-year-old man (D). 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{"pdf_hash": "653d6c43887abd0c082be7cf13c23618e6e7fd11", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (a) A radiograph of the right leg shows a cookie bite at the diaphysis of right proximal tibia indicating an eccentric osteolytic cortical lesion (arrow). (b) Posteroanterior radiograph of the chest shows a soft tissue mass (arrow) in the retrocardiac region of left lower lung.", "width": 942, "height": 628, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57]}, "subfigures": [{"id": "0abc42eb-6118-4d10-9100-b72cb059e99d", "label": "a", "points": [[6, 7.4], [6, 593.8], [386.9, 593.8], [386.9, 7.4]], "color": "yellow"}, {"id": "769346ff-9695-4874-8632-ddc0fd4f089b", "label": "b", "points": [[939, 6], [939, 595.3], [388.4, 595.3], [388.4, 6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "A", "start": 14, "end": 15, "id": 6}, {"text": "radiograph", "start": 16, "end": 26, "id": 7}, {"text": "of", "start": 27, "end": 29, "id": 8}, {"text": "the", "start": 30, "end": 33, "id": 9}, {"text": "right", "start": 34, "end": 39, "id": 10}, {"text": "leg", "start": 40, "end": 43, "id": 11}, {"text": "shows", "start": 44, "end": 49, "id": 12}, {"text": "a", "start": 50, "end": 51, "id": 13}, {"text": "cookie", "start": 52, "end": 58, "id": 14}, {"text": "bite", "start": 59, "end": 63, "id": 15}, {"text": "at", "start": 64, "end": 66, "id": 16}, {"text": "the", "start": 67, "end": 70, "id": 17}, {"text": "diaphysis", "start": 71, "end": 80, "id": 18}, {"text": "of", "start": 81, "end": 83, "id": 19}, {"text": "right", "start": 84, "end": 89, "id": 20}, {"text": "proximal", "start": 90, "end": 98, "id": 21}, {"text": "tibia", "start": 99, "end": 104, "id": 22}, {"text": "indicating", "start": 105, "end": 115, "id": 23}, {"text": "an", "start": 116, "end": 118, "id": 24}, {"text": "eccentric", "start": 119, "end": 128, "id": 25}, {"text": "osteolytic", "start": 129, "end": 139, "id": 26}, {"text": "cortical", "start": 140, "end": 148, "id": 27}, {"text": "lesion", "start": 149, "end": 155, "id": 28}, {"text": "(", "start": 156, "end": 157, "id": 29}, {"text": "arrow", "start": 157, "end": 162, "id": 30}, {"text": ")", "start": 162, "end": 163, "id": 31}, {"text": ".", "start": 163, "end": 164, "id": 32}, {"text": "(", "start": 165, "end": 166, "id": 33}, {"text": "b", "start": 166, "end": 167, "id": 34}, {"text": ")", "start": 167, "end": 168, "id": 35}, {"text": "Posteroanterior", "start": 169, "end": 184, "id": 36}, {"text": "radiograph", "start": 185, "end": 195, "id": 37}, {"text": "of", "start": 196, "end": 198, "id": 38}, {"text": "the", "start": 199, "end": 202, "id": 39}, {"text": "chest", "start": 203, "end": 208, "id": 40}, {"text": "shows", "start": 209, "end": 214, "id": 41}, {"text": "a", "start": 215, "end": 216, "id": 42}, {"text": "soft", "start": 217, "end": 221, "id": 43}, {"text": "tissue", "start": 222, "end": 228, "id": 44}, {"text": "mass", "start": 229, "end": 233, "id": 45}, {"text": "(", "start": 234, "end": 235, "id": 46}, {"text": "arrow", "start": 235, "end": 240, "id": 47}, {"text": ")", "start": 240, "end": 241, "id": 48}, {"text": "in", "start": 242, "end": 244, "id": 49}, {"text": "the", "start": 245, "end": 248, "id": 50}, {"text": "retrocardiac", "start": 249, "end": 261, "id": 51}, {"text": "region", "start": 262, "end": 268, "id": 52}, {"text": "of", "start": 269, "end": 271, "id": 53}, {"text": "left", "start": 272, "end": 276, "id": 54}, {"text": "lower", "start": 277, "end": 282, "id": 55}, {"text": "lung", "start": 283, "end": 287, "id": 56}, {"text": ".", "start": 287, "end": 288, "id": 57}]}
{"pdf_hash": "b5fc5c5069f8cc41aaaf7af94441d136c1c65a92", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Brain magnetic resonance imaging. (A) and (B) are MRIs taken before the thiamine treatment, while (C) and (D) are from 5 mo after the thiamine treatment. A: Symmetrical high T2 signal intensities in pons; B: Symmetrical high T2 signal intensities in paraventricular area; C: Reduction of abnormal signal in pons; D: Reduction of abnormal signal in paraventricular area. MRI: Magnetic resonance imaging.", "width": 1150, "height": 758, "subcaptions": {"a": [7, 8, 9, 39, 40, 41, 42, 14, 15, 16, 17, 18, 19, 20, 44, 45, 46, 47, 43], "b": [56, 58, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 49, 50, 51, 52, 53, 54, 55, 57], "c": [32, 33, 34, 35, 36, 37, 38, 64, 65, 66, 67, 63, 62, 23, 24, 25, 60, 61, 30, 31], "d": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78]}, "subfigures": [{"id": "6e6a6fb7-81c4-443c-adde-8490d98b3409", "label": "a", "points": [[3.7, 5.2], [3.7, 390.3], [352.5, 390.3], [352.5, 5.2]], "color": "yellow"}, {"id": "6fe317c9-8c4c-427b-9244-b92e6de43a68", "label": "b", "points": [[372.5, -0.3], [372.5, 395.7], [748.5, 395.7], [748.5, -0.3]], "color": "cyan"}, {"id": "e2388d0e-2a56-4951-bdc1-8e8463ff6874", "label": "c", "points": [[757.6, -0.3], [757.6, 393.9], [1146.4, 393.9], [1146.4, -0.3]], "color": "magenta"}, {"id": "b3aafc5a-cdb3-49d9-9a40-207955716703", "label": "d", "points": [[7.3, 403], [7.3, 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{"pdf_hash": "18cb9fa53960e3af9136146d4d65fc0b73e40f49", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4 Patient no. 2, 54-yearold man, presented with left hemiparesthesia and dysarthria after physical exercise. Coronal MIP reconstruction of 3D T1 FS SPACE (a) shows the subacute mural hematoma in the cervical right ICA (black arrowhead). MIP reconstruction of gadoliniumenhanced MR angiography of the head and neck vessels (b) shows a tapering stenosis of the ICA and two distal pseudoaneurysms (white arrow)", "width": 902, "height": 868, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "b": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76]}, "subfigures": [{"id": "15600f76-f015-4c3a-9352-459d36448865", "label": "a", "points": [[35.9, 41.8], [35.9, 866.9], [717, 866.9], [717, 41.8]], "color": "yellow"}, {"id": "1122d7e6-c1ac-44d2-bbc3-56b8d4072fc0", "label": "b", "points": [[719.9, 37.5], [719.9, 864], [896.6, 864], [896.6, 37.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Patient", "start": 7, "end": 14, "id": 3}, {"text": "no", "start": 15, "end": 17, "id": 4}, {"text": ".", "start": 17, "end": 18, "id": 5}, {"text": "2", "start": 19, "end": 20, "id": 6}, {"text": ",", "start": 20, "end": 21, "id": 7}, {"text": "54-yearold", "start": 22, "end": 32, "id": 8}, {"text": "man", "start": 33, "end": 36, "id": 9}, {"text": ",", "start": 36, "end": 37, "id": 10}, {"text": "presented", "start": 38, "end": 47, "id": 11}, {"text": "with", "start": 48, "end": 52, "id": 12}, {"text": "left", "start": 53, "end": 57, "id": 13}, {"text": "hemiparesthesia", "start": 58, "end": 73, "id": 14}, {"text": "and", "start": 74, "end": 77, "id": 15}, {"text": "dysarthria", "start": 78, "end": 88, "id": 16}, {"text": "after", "start": 89, "end": 94, "id": 17}, {"text": "physical", "start": 95, "end": 103, "id": 18}, {"text": "exercise", "start": 104, "end": 112, "id": 19}, {"text": ".", "start": 112, "end": 113, "id": 20}, {"text": "Coronal", "start": 114, "end": 121, "id": 21}, {"text": "MIP", "start": 122, "end": 125, "id": 22}, {"text": "reconstruction", "start": 126, "end": 140, "id": 23}, {"text": "of", "start": 141, "end": 143, "id": 24}, {"text": "3D", "start": 144, "end": 146, "id": 25}, {"text": "T1", "start": 147, "end": 149, "id": 26}, {"text": "FS", "start": 150, "end": 152, "id": 27}, {"text": "SPACE", "start": 153, "end": 158, "id": 28}, {"text": "(", "start": 159, "end": 160, "id": 29}, {"text": "a", "start": 160, "end": 161, "id": 30}, {"text": ")", "start": 161, "end": 162, "id": 31}, {"text": "shows", "start": 163, "end": 168, "id": 32}, {"text": "the", "start": 169, "end": 172, "id": 33}, {"text": "subacute", "start": 173, "end": 181, "id": 34}, {"text": "mural", "start": 182, "end": 187, "id": 35}, {"text": "hematoma", "start": 188, "end": 196, "id": 36}, {"text": "in", "start": 197, "end": 199, "id": 37}, {"text": "the", "start": 200, "end": 203, "id": 38}, {"text": "cervical", "start": 204, "end": 212, "id": 39}, {"text": "right", "start": 213, "end": 218, "id": 40}, {"text": "ICA", "start": 219, "end": 222, "id": 41}, {"text": "(", "start": 223, "end": 224, "id": 42}, {"text": "black", "start": 224, "end": 229, "id": 43}, {"text": "arrowhead", "start": 230, "end": 239, "id": 44}, {"text": ")", "start": 239, "end": 240, "id": 45}, {"text": ".", "start": 240, "end": 241, "id": 46}, {"text": "MIP", "start": 242, "end": 245, "id": 47}, {"text": "reconstruction", "start": 246, "end": 260, "id": 48}, {"text": "of", "start": 261, "end": 263, "id": 49}, {"text": "gadoliniumenhanced", "start": 264, "end": 282, "id": 50}, {"text": "MR", "start": 283, "end": 285, "id": 51}, {"text": "angiography", "start": 286, "end": 297, "id": 52}, {"text": "of", "start": 298, "end": 300, "id": 53}, {"text": "the", "start": 301, "end": 304, "id": 54}, {"text": "head", "start": 305, "end": 309, "id": 55}, {"text": "and", "start": 310, "end": 313, "id": 56}, {"text": "neck", "start": 314, "end": 318, "id": 57}, {"text": "vessels", "start": 319, "end": 326, "id": 58}, {"text": "(", "start": 327, "end": 328, "id": 59}, {"text": "b", "start": 328, "end": 329, "id": 60}, {"text": ")", "start": 329, "end": 330, "id": 61}, {"text": "shows", "start": 331, "end": 336, "id": 62}, {"text": "a", "start": 337, "end": 338, "id": 63}, {"text": "tapering", "start": 339, "end": 347, "id": 64}, {"text": "stenosis", "start": 348, "end": 356, "id": 65}, {"text": "of", "start": 357, "end": 359, "id": 66}, {"text": "the", "start": 360, "end": 363, "id": 67}, {"text": "ICA", "start": 364, "end": 367, "id": 68}, {"text": "and", "start": 368, "end": 371, "id": 69}, {"text": "two", "start": 372, "end": 375, "id": 70}, {"text": "distal", "start": 376, "end": 382, "id": 71}, {"text": "pseudoaneurysms", "start": 383, "end": 398, "id": 72}, {"text": "(", "start": 399, "end": 400, "id": 73}, {"text": "white", "start": 400, "end": 405, "id": 74}, {"text": "arrow", "start": 406, "end": 411, "id": 75}, {"text": ")", "start": 411, "end": 412, "id": 76}]}
{"pdf_hash": "9ab3b4060101329a1ace1eae6314447338a70671", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2 Ubiquitin C-terminal hydrolase-L1 protein (UCH-L1) and glial fibrillary acidic protein (GFAP) dynamics in human serum after acute injury. (a and b) Computed tomography scans demonstrating focal and diffuse brain injury in individual patients. (c and d) UCH-L1 (green circles) and GFAP (blue triangles) serum concentrations measured every six hours in corresponding individual patients. 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{"pdf_hash": "aca3c952330de703f7b01d296a395e77b79fb9a4", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 Photomicrographs of parasagittal sections of murine tongue illustrating protection from DXR-induced apoptosis. Mice were orally treated with unrelated antibody (A), or with anti-anthracycline antibody (B\u2013C), and 2 h later i.v. injected with 30 mg/kg of DXR. The tongues were evaluated 4 (A\u2013B) or 24 (C) h later. 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{"pdf_hash": "b092a75dcc051e0178c99b30881b2bb183c4141c", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1. Female patient, aged 63 years, with back pain for 3 months, who underwent percutaneous kyphoplasty (PKP). (A\u2013C) Preoperative lateral x-ray and CT scan showed L1 vertebral fracture with vacuum-like changes, MRI showed low signal of the necrotic area on T2-weighted images. 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{"pdf_hash": "478e9ffc8a9d2d11129c2ca039d0c5fac18eb153", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Figure 4 Longitudinal sections of flowers of Lacandonia brasiliana (LM). (A, B) Longitudinal sections of unopened buds showing central stamens at a pre-meiotic stage, with anther wall layers already visible surrounding sporogenous cells. The carpels have not yet begun to differentiate ovules. Filamentous appendages have begun to grow from the tips of the tepals. (C) Longitudinal section of inflorescence with three unopened buds at different stages, the youngest flower primordium lacking organs. (D) Longitudinal section of later stage; individual pollen grains visible in anther locules; ovules at megaspore mother stage with developing integuments. Filamentous tepal appendages have extended down between the anthers. (E) Transverse section of an apical tepal appendage showing central vasculature. Labels: ca,carpel; fta,filamentous tepal appendage; st,stamen; yp,young flower primordium. 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{"pdf_hash": "4bfc7715d03cbeb88da8a7442e8f74132049c06b", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure\u00a0 2: (a) T2 magnetic resonance (MR) weighted images showing the descent of cerebellar tonsils through the foramen magnum and the compression of the medulla oblongata, (b) T2-weighted postoperative MR in sagittal plane demonstrates the repositioning of cerebellar tonsils and the enlargement of subarachnoid spaces of posterior cranial fossa.", "width": 724, "height": 384, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "0b93fb89-d4a3-4e13-81cc-e92114fcd9aa", "label": "a", "points": [[31.1, 1.5], [31.1, 344.7], [379.9, 344.7], [379.9, 1.5]], "color": "yellow"}, {"id": "742b8b8e-382b-4ddd-89ea-4c39ca91ce71", "label": "b", "points": [[398.2, 6.1], [398.2, 345.8], [700.2, 345.8], [700.2, 6.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "\u00a0 ", "start": 6, "end": 8, "id": 1}, {"text": "2", "start": 8, "end": 9, "id": 2}, {"text": ":", "start": 9, "end": 10, "id": 3}, {"text": "(", "start": 11, "end": 12, "id": 4}, {"text": "a", "start": 12, "end": 13, "id": 5}, {"text": ")", "start": 13, "end": 14, "id": 6}, {"text": "T2", "start": 15, "end": 17, "id": 7}, {"text": "magnetic", "start": 18, "end": 26, "id": 8}, {"text": "resonance", "start": 27, "end": 36, "id": 9}, {"text": "(", "start": 37, "end": 38, "id": 10}, {"text": "MR", "start": 38, "end": 40, "id": 11}, {"text": ")", "start": 40, "end": 41, "id": 12}, {"text": "weighted", "start": 42, "end": 50, "id": 13}, {"text": "images", "start": 51, "end": 57, "id": 14}, {"text": "showing", "start": 58, "end": 65, "id": 15}, {"text": "the", "start": 66, "end": 69, "id": 16}, {"text": "descent", "start": 70, "end": 77, "id": 17}, {"text": "of", "start": 78, "end": 80, "id": 18}, {"text": "cerebellar", "start": 81, "end": 91, "id": 19}, {"text": "tonsils", "start": 92, "end": 99, "id": 20}, {"text": "through", "start": 100, "end": 107, "id": 21}, {"text": "the", "start": 108, "end": 111, "id": 22}, {"text": "foramen", "start": 112, "end": 119, "id": 23}, {"text": "magnum", "start": 120, "end": 126, "id": 24}, {"text": "and", "start": 127, "end": 130, "id": 25}, {"text": "the", "start": 131, "end": 134, "id": 26}, {"text": "compression", "start": 135, "end": 146, "id": 27}, {"text": "of", "start": 147, "end": 149, "id": 28}, {"text": "the", "start": 150, "end": 153, "id": 29}, {"text": "medulla", "start": 154, "end": 161, "id": 30}, {"text": "oblongata", "start": 162, "end": 171, "id": 31}, {"text": ",", "start": 171, "end": 172, "id": 32}, {"text": "(", "start": 173, "end": 174, "id": 33}, {"text": "b", "start": 174, "end": 175, "id": 34}, {"text": ")", "start": 175, "end": 176, "id": 35}, {"text": "T2-weighted", "start": 177, "end": 188, "id": 36}, {"text": "postoperative", "start": 189, "end": 202, "id": 37}, {"text": "MR", "start": 203, "end": 205, "id": 38}, {"text": "in", "start": 206, "end": 208, "id": 39}, {"text": "sagittal", "start": 209, "end": 217, "id": 40}, {"text": "plane", "start": 218, "end": 223, "id": 41}, {"text": "demonstrates", "start": 224, "end": 236, "id": 42}, {"text": "the", "start": 237, "end": 240, "id": 43}, {"text": "repositioning", "start": 241, "end": 254, "id": 44}, {"text": "of", "start": 255, "end": 257, "id": 45}, {"text": "cerebellar", "start": 258, "end": 268, "id": 46}, {"text": "tonsils", "start": 269, "end": 276, "id": 47}, {"text": "and", "start": 277, "end": 280, "id": 48}, {"text": "the", "start": 281, "end": 284, "id": 49}, {"text": "enlargement", "start": 285, "end": 296, "id": 50}, {"text": "of", "start": 297, "end": 299, "id": 51}, {"text": "subarachnoid", "start": 300, "end": 312, "id": 52}, {"text": "spaces", "start": 313, "end": 319, "id": 53}, {"text": "of", "start": 320, "end": 322, "id": 54}, {"text": "posterior", "start": 323, "end": 332, "id": 55}, {"text": "cranial", "start": 333, "end": 340, "id": 56}, {"text": "fossa", "start": 341, "end": 346, "id": 57}, {"text": ".", "start": 346, "end": 347, "id": 58}]}
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{"pdf_hash": "5ef8ec271dcd599b558b59961df55f5ba27c4508", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. Immunohistochemical localization of nuclear factor of activated T cells (NFAT) in rat testes. Asterisks indicate Leydig cells that were positively stained for NFAT. (A): NFAT2 expression in Leydig cells. (B): NFAT2 immunostainings were abolished by incubating with Phosphate-buffered saline (PBS) buffer instead of anti-NFAT antibody. Scale bar = 50 \u03bcm.", "width": 652, "height": 316, "subcaptions": {"a": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65]}, "subfigures": [{"id": "7fc9bb94-129c-420f-98be-cfae99ea2c5e", "label": "a", "points": [[23.7, 2.1], [23.7, 284.3], [307, 284.3], [307, 2.1]], "color": "yellow"}, {"id": "b037e605-9f13-4f4d-abe2-b065e0b37335", "label": "b", "points": [[343, 5.2], [343, 282.2], [624.2, 282.2], [624.2, 5.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Immunohistochemical", "start": 10, "end": 29, "id": 3}, {"text": "localization", "start": 30, "end": 42, "id": 4}, {"text": "of", "start": 43, "end": 45, "id": 5}, {"text": "nuclear", "start": 46, "end": 53, "id": 6}, {"text": "factor", "start": 54, "end": 60, "id": 7}, {"text": "of", "start": 61, "end": 63, "id": 8}, {"text": "activated", "start": 64, "end": 73, "id": 9}, {"text": "T", "start": 74, "end": 75, "id": 10}, {"text": "cells", "start": 76, "end": 81, "id": 11}, {"text": "(", "start": 82, "end": 83, "id": 12}, {"text": "NFAT", "start": 83, "end": 87, "id": 13}, {"text": ")", "start": 87, "end": 88, "id": 14}, {"text": "in", "start": 89, "end": 91, "id": 15}, {"text": "rat", "start": 92, "end": 95, "id": 16}, {"text": "testes", "start": 96, "end": 102, "id": 17}, {"text": ".", "start": 102, "end": 103, "id": 18}, {"text": "Asterisks", "start": 104, "end": 113, "id": 19}, {"text": "indicate", "start": 114, "end": 122, "id": 20}, {"text": "Leydig", "start": 123, "end": 129, "id": 21}, {"text": "cells", "start": 130, "end": 135, "id": 22}, {"text": "that", "start": 136, "end": 140, "id": 23}, {"text": "were", "start": 141, "end": 145, "id": 24}, {"text": "positively", "start": 146, "end": 156, "id": 25}, {"text": "stained", "start": 157, "end": 164, "id": 26}, {"text": "for", "start": 165, "end": 168, "id": 27}, {"text": "NFAT", "start": 169, "end": 173, "id": 28}, {"text": ".", "start": 173, "end": 174, "id": 29}, {"text": "(", "start": 175, "end": 176, "id": 30}, {"text": "A", "start": 176, "end": 177, "id": 31}, {"text": ")", "start": 177, "end": 178, "id": 32}, {"text": ":", "start": 178, "end": 179, "id": 33}, {"text": "NFAT2", "start": 180, "end": 185, "id": 34}, {"text": "expression", "start": 186, "end": 196, "id": 35}, {"text": "in", "start": 197, "end": 199, "id": 36}, {"text": "Leydig", "start": 200, "end": 206, "id": 37}, {"text": "cells", "start": 207, "end": 212, "id": 38}, {"text": ".", "start": 212, "end": 213, "id": 39}, {"text": "(", "start": 214, "end": 215, "id": 40}, {"text": "B", "start": 215, "end": 216, "id": 41}, {"text": ")", "start": 216, "end": 217, "id": 42}, {"text": ":", "start": 217, "end": 218, "id": 43}, {"text": "NFAT2", "start": 219, "end": 224, "id": 44}, {"text": "immunostainings", "start": 225, "end": 240, "id": 45}, {"text": "were", "start": 241, "end": 245, "id": 46}, {"text": "abolished", "start": 246, "end": 255, "id": 47}, {"text": "by", "start": 256, "end": 258, "id": 48}, {"text": "incubating", "start": 259, "end": 269, "id": 49}, {"text": "with", "start": 270, "end": 274, "id": 50}, {"text": "Phosphate", "start": 275, "end": 284, "id": 51}, {"text": "-", "start": 284, "end": 285, "id": 52}, {"text": "buffered", "start": 285, "end": 293, "id": 53}, {"text": "saline", "start": 294, "end": 300, "id": 54}, {"text": "(", "start": 301, "end": 302, "id": 55}, {"text": "PBS", "start": 302, "end": 305, "id": 56}, {"text": ")", "start": 305, "end": 306, "id": 57}, {"text": "buffer", "start": 307, "end": 313, "id": 58}, {"text": "instead", "start": 314, "end": 321, "id": 59}, {"text": "of", "start": 322, "end": 324, "id": 60}, {"text": "anti", "start": 325, "end": 329, "id": 61}, {"text": "-", "start": 329, "end": 330, "id": 62}, {"text": "NFAT", "start": 330, "end": 334, "id": 63}, {"text": "antibody", "start": 335, "end": 343, "id": 64}, {"text": ".", "start": 343, "end": 344, "id": 65}, {"text": "Scale", "start": 345, "end": 350, "id": 66}, {"text": "bar", "start": 351, "end": 354, "id": 67}, {"text": "=", "start": 355, "end": 356, "id": 68}, {"text": "50", "start": 357, "end": 359, "id": 69}, {"text": "\u03bcm", "start": 360, "end": 362, "id": 70}, {"text": ".", "start": 362, "end": 363, "id": 71}]}
{"pdf_hash": "4393e4e8a335a1760043fdb4e3cbb9e1829ff8c3", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Histology of the biopsy specimens. (A) A biopsy specimen of the duodenum with dilated villi. (B) Aggregation of foamy macrophages in the lamina propria. (C) Diastase-resistant-positive particles found in the cytoplasm of foamy macrophages. (D) High magnification of a PAS stain (D), a Warthin-Starry stain (E) and an acid-fast stain (F). (G-H) Histology of the biopsy specimens of the duodenum obtained during the follow-up endoscopic examination performed three months after treatment. (G) Duodenal mucosa with slightly swollen villi. (H) Diastase-resistant PAS-positive particles remaining in the cytoplasm of foamy macrophages. (Original magnification; A: \u00d710. B, C: \u00d7100. D-F: \u00d7400. G: \u00d740. 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{"pdf_hash": "dbfc8007645b8b52d3f5a317832177af851ac1a6", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4. Fate of mouse crest cells transplanted in ovo. (A) Macroscopic view of a mouse/chick chimera examined 3.5 days after implantation (10- somite stage) at unsegmented plate level with 9 dpc Rosa 26 mouse caudal neural tube. Mouse neural tube cells and their derivatives (arrows) expressing \u03b2-galactosidase are identified by LacZ staining. Transverse section of a mouse/chick chimera examined 4 days after implantation (17-somite stage) at the 13-17 somite level with 9 dpc mouse caudal neural tube. (B) Neurofilament immunostaining. Note the positive nerves emerging from the implanted tube (arrow). 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{"pdf_hash": "25fa108ae672e490cfb8833c16b846b0ad2be7b9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Axial fluid attenuated inversion recovery magnetic resonance imaging scan (top) and sagittal reconstruction T2-weighted magnetic resonance imaging scan (bottom) show an area of increased signal consistent with an ischemic stroke in the left paramedian dorsal pontine tegmentum, adjacent to the fourth ventricle.", "width": 634, "height": 964, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "b": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50]}, "subfigures": [{"id": "716a6c73-f0c8-4457-b576-51d69f1c2a18", "label": "a", "points": [[0, 2], [0, 478.8], [633, 478.8], [633, 2]], "color": "yellow"}, {"id": "3ab00555-80d9-4b0d-b974-ad0c86c59be5", "label": "b", "points": [[4, 490.8], [4, 930.5], [632, 930.5], [632, 490.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Axial", "start": 10, "end": 15, "id": 3}, {"text": "fluid", "start": 16, "end": 21, "id": 4}, {"text": "attenuated", "start": 22, "end": 32, "id": 5}, {"text": "inversion", "start": 33, "end": 42, "id": 6}, {"text": "recovery", "start": 43, "end": 51, "id": 7}, {"text": "magnetic", "start": 52, "end": 60, "id": 8}, {"text": "resonance", "start": 61, "end": 70, "id": 9}, {"text": "imaging", "start": 71, "end": 78, "id": 10}, {"text": "scan", "start": 79, "end": 83, "id": 11}, {"text": "(", "start": 84, "end": 85, "id": 12}, {"text": "top", "start": 85, "end": 88, "id": 13}, {"text": ")", "start": 88, "end": 89, "id": 14}, {"text": "and", "start": 90, "end": 93, "id": 15}, {"text": "sagittal", "start": 94, "end": 102, "id": 16}, {"text": "reconstruction", "start": 103, "end": 117, "id": 17}, {"text": "T2-weighted", "start": 118, "end": 129, "id": 18}, {"text": "magnetic", "start": 130, "end": 138, "id": 19}, {"text": "resonance", "start": 139, "end": 148, "id": 20}, {"text": "imaging", "start": 149, "end": 156, "id": 21}, {"text": "scan", "start": 157, "end": 161, "id": 22}, {"text": "(", "start": 162, "end": 163, "id": 23}, {"text": "bottom", "start": 163, "end": 169, "id": 24}, {"text": ")", "start": 169, "end": 170, "id": 25}, {"text": "show", "start": 171, "end": 175, "id": 26}, {"text": "an", "start": 176, "end": 178, "id": 27}, {"text": "area", "start": 179, "end": 183, "id": 28}, {"text": "of", "start": 184, "end": 186, "id": 29}, {"text": "increased", "start": 187, "end": 196, "id": 30}, {"text": "signal", "start": 197, "end": 203, "id": 31}, {"text": "consistent", "start": 204, "end": 214, "id": 32}, {"text": "with", "start": 215, "end": 219, "id": 33}, {"text": "an", "start": 220, "end": 222, "id": 34}, {"text": "ischemic", "start": 223, "end": 231, "id": 35}, {"text": "stroke", "start": 232, "end": 238, "id": 36}, {"text": "in", "start": 239, "end": 241, "id": 37}, {"text": "the", "start": 242, "end": 245, "id": 38}, {"text": "left", "start": 246, "end": 250, "id": 39}, {"text": "paramedian", "start": 251, "end": 261, "id": 40}, {"text": "dorsal", "start": 262, "end": 268, "id": 41}, {"text": "pontine", "start": 269, "end": 276, "id": 42}, {"text": "tegmentum", "start": 277, "end": 286, "id": 43}, {"text": ",", "start": 286, "end": 287, "id": 44}, {"text": "adjacent", "start": 288, "end": 296, "id": 45}, {"text": "to", "start": 297, "end": 299, "id": 46}, {"text": "the", "start": 300, "end": 303, "id": 47}, {"text": "fourth", "start": 304, "end": 310, "id": 48}, {"text": "ventricle", "start": 311, "end": 320, "id": 49}, {"text": ".", "start": 320, "end": 321, "id": 50}]}
{"pdf_hash": "807563ff52196cd80dcb27a71644d9a4cd00715c", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. Coronal (A) and sagittal (B) post-contrast magnetic resonance images 16 months after the cerebrospinal fluid (CSF) leak repair show resolution of the dural enhancement and subdural hygromas seen in Figure 1 (C-D). Note the presence of a vascularized septal flap (arrow, B) and return of the brainstem and cerebellum to a normal anatomic position in comparison to the inferior displacement noted in Figure 1 (D). These findings indicate full resolution of intracranial hypotension caused by the CSF leak.", "width": 654, "height": 874, "subcaptions": {"a": [3, 4, 5, 6, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86]}, "subfigures": [{"id": "24ce80ec-71ce-473d-b9d8-2ba46b30663e", "label": "a", "points": [[12.6, 17.9], [12.6, 442.6], [645.9, 442.6], [645.9, 17.9]], "color": "yellow"}, {"id": "47a91243-52ea-488d-b239-368d7352663c", "label": "b", "points": [[8.4, 445.3], [8.4, 855.5], [639.7, 855.5], [639.7, 445.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, 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{"pdf_hash": "d96523cd68944e4a24299f24d57f3800811b782c", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: Airway reconstructions from the chest CT. (A) Anterioposterior view of the trachea: a significant compression at the distal trachea (C: carina; T: trachea; white asteroid: external compression of the trachea). 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{"pdf_hash": "7acced6afc150bbb109d2433653fdec7aaa9e0dc", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Chest x-ray after fibrin glue injection. Chest x-ray at 30 min (a) and 12 h (b) after fibrin glue injection. A minimal PTX was appreciable in (a) and disappeared in (b). 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{"pdf_hash": "b3b4e33dba5237e725ffde81c2d50742ec6910b7", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A: Chest HRCT scan in January 2001, showing a nodular shadow in the cavity lesion in the right S3, and reticulonodular, cystic, and ground-grass opacities in the bilateral lung fields, predominantly in the subpleural areas with honeycombing in the bilateral lower zones. B: Chest HRCT scan in September 2002, showing exacerbation of the opacities.", "width": 668, "height": 630, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "b": [54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "247a0d57-9261-4fec-ae49-decdca7a0528", "label": "a", "points": [[1.2, 0.4], [1.2, 292.7], [667.1, 292.7], [667.1, 0.4]], "color": "yellow"}, {"id": "2def638f-88a5-43ea-8efd-5f5f59990254", "label": "b", "points": [[0.2, 333.8], [0.2, 627.2], [667.1, 627.2], [667.1, 333.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ":", "start": 11, "end": 12, "id": 4}, {"text": "Chest", "start": 13, "end": 18, "id": 5}, {"text": "HRCT", "start": 19, "end": 23, "id": 6}, {"text": "scan", "start": 24, "end": 28, "id": 7}, {"text": "in", "start": 29, "end": 31, "id": 8}, {"text": "January", "start": 32, "end": 39, "id": 9}, {"text": "2001", "start": 40, "end": 44, "id": 10}, {"text": ",", "start": 44, "end": 45, "id": 11}, {"text": "showing", "start": 46, "end": 53, "id": 12}, {"text": "a", "start": 54, "end": 55, "id": 13}, {"text": "nodular", "start": 56, "end": 63, "id": 14}, {"text": "shadow", "start": 64, "end": 70, "id": 15}, {"text": "in", "start": 71, "end": 73, "id": 16}, {"text": "the", "start": 74, "end": 77, "id": 17}, {"text": "cavity", "start": 78, "end": 84, "id": 18}, {"text": "lesion", "start": 85, "end": 91, "id": 19}, {"text": "in", "start": 92, "end": 94, "id": 20}, {"text": "the", "start": 95, "end": 98, "id": 21}, {"text": "right", "start": 99, "end": 104, "id": 22}, {"text": "S3", "start": 105, "end": 107, "id": 23}, {"text": ",", "start": 107, "end": 108, "id": 24}, {"text": "and", "start": 109, "end": 112, "id": 25}, {"text": "reticulonodular", "start": 113, "end": 128, "id": 26}, {"text": ",", "start": 128, "end": 129, "id": 27}, {"text": "cystic", "start": 130, "end": 136, "id": 28}, {"text": ",", "start": 136, "end": 137, "id": 29}, {"text": "and", "start": 138, "end": 141, "id": 30}, {"text": "ground", "start": 142, "end": 148, "id": 31}, {"text": "-", "start": 148, "end": 149, "id": 32}, {"text": "grass", "start": 149, "end": 154, "id": 33}, {"text": "opacities", "start": 155, "end": 164, "id": 34}, {"text": "in", "start": 165, "end": 167, "id": 35}, {"text": "the", "start": 168, "end": 171, "id": 36}, {"text": "bilateral", "start": 172, "end": 181, "id": 37}, {"text": "lung", "start": 182, "end": 186, "id": 38}, {"text": "fields", "start": 187, "end": 193, "id": 39}, {"text": ",", "start": 193, "end": 194, "id": 40}, {"text": "predominantly", "start": 195, "end": 208, "id": 41}, {"text": "in", "start": 209, "end": 211, "id": 42}, {"text": "the", "start": 212, "end": 215, "id": 43}, {"text": "subpleural", "start": 216, "end": 226, "id": 44}, {"text": "areas", "start": 227, "end": 232, "id": 45}, {"text": "with", "start": 233, "end": 237, "id": 46}, {"text": "honeycombing", "start": 238, "end": 250, "id": 47}, {"text": "in", "start": 251, "end": 253, "id": 48}, {"text": "the", "start": 254, "end": 257, "id": 49}, {"text": "bilateral", "start": 258, "end": 267, "id": 50}, {"text": "lower", "start": 268, "end": 273, "id": 51}, {"text": "zones", "start": 274, "end": 279, "id": 52}, {"text": ".", "start": 279, "end": 280, "id": 53}, {"text": "B", "start": 281, "end": 282, "id": 54}, {"text": ":", "start": 282, "end": 283, "id": 55}, {"text": "Chest", "start": 284, "end": 289, "id": 56}, {"text": "HRCT", "start": 290, "end": 294, "id": 57}, {"text": "scan", "start": 295, "end": 299, "id": 58}, {"text": "in", "start": 300, "end": 302, "id": 59}, {"text": "September", "start": 303, "end": 312, "id": 60}, {"text": "2002", "start": 313, "end": 317, "id": 61}, {"text": ",", "start": 317, "end": 318, "id": 62}, {"text": "showing", "start": 319, "end": 326, "id": 63}, {"text": "exacerbation", "start": 327, "end": 339, "id": 64}, {"text": "of", "start": 340, "end": 342, "id": 65}, {"text": "the", "start": 343, "end": 346, "id": 66}, {"text": "opacities", "start": 347, "end": 356, "id": 67}, {"text": ".", "start": 356, "end": 357, "id": 68}]}
{"pdf_hash": "59a50aa035dfc2df3d6d027e3a83b169631a4640", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. CT images of healthy lung tissue biopsies. (A) Healthy lung before biopsy. (B) Lung image after injection of 2\u20133 ml stroke-physiological saline solution. (C) CT-guided biopsy. White arrow = syringe, black arrow = exudative area after injecting 2\u20133 ml strokephysiological saline solution, white arrowhead = core needle.", "width": 640, "height": 264, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "c": [36, 37, 38, 39, 40, 41, 42, 43]}, "subfigures": [{"id": "7be31165-bde3-4bf9-a52d-71bc33cde89e", "label": "a", "points": [[8.6, 5.1], [8.6, 226.5], [213.8, 226.5], [213.8, 5.1]], "color": "yellow"}, {"id": "5302f0e6-6b7d-4cc1-bbbd-e1df4122e7bf", "label": "b", "points": [[220.9, 3], [220.9, 226.5], [430.2, 226.5], [430.2, 3]], "color": "cyan"}, {"id": "7c7e9626-4e4d-46b0-a4f7-5224031ff54d", "label": "c", "points": [[435.3, 0], [435.3, 227.5], [637.5, 227.5], [637.5, 0]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "CT", "start": 8, "end": 10, "id": 4}, {"text": "images", "start": 11, "end": 17, "id": 5}, {"text": "of", "start": 18, "end": 20, "id": 6}, {"text": "healthy", "start": 21, "end": 28, "id": 7}, {"text": "lung", "start": 29, "end": 33, "id": 8}, {"text": "tissue", "start": 34, "end": 40, "id": 9}, {"text": "biopsies", "start": 41, "end": 49, "id": 10}, {"text": ".", "start": 49, "end": 50, "id": 11}, {"text": "(", "start": 51, "end": 52, "id": 12}, {"text": "A", "start": 52, "end": 53, "id": 13}, {"text": ")", "start": 53, "end": 54, "id": 14}, {"text": "Healthy", "start": 55, "end": 62, "id": 15}, {"text": "lung", "start": 63, "end": 67, "id": 16}, {"text": "before", "start": 68, "end": 74, "id": 17}, {"text": "biopsy", "start": 75, "end": 81, "id": 18}, {"text": ".", "start": 81, "end": 82, "id": 19}, {"text": "(", "start": 83, "end": 84, "id": 20}, {"text": "B", "start": 84, "end": 85, "id": 21}, {"text": ")", "start": 85, "end": 86, "id": 22}, {"text": "Lung", "start": 87, "end": 91, "id": 23}, {"text": "image", "start": 92, "end": 97, "id": 24}, {"text": "after", "start": 98, "end": 103, "id": 25}, {"text": "injection", "start": 104, "end": 113, "id": 26}, {"text": "of", "start": 114, "end": 116, "id": 27}, {"text": "2\u20133", "start": 117, "end": 120, "id": 28}, {"text": "ml", "start": 121, "end": 123, "id": 29}, {"text": "stroke", "start": 124, "end": 130, "id": 30}, {"text": "-", "start": 130, "end": 131, "id": 31}, {"text": "physiological", "start": 131, "end": 144, "id": 32}, {"text": "saline", "start": 145, "end": 151, "id": 33}, {"text": "solution", "start": 152, "end": 160, "id": 34}, {"text": ".", "start": 160, "end": 161, "id": 35}, {"text": "(", "start": 162, "end": 163, "id": 36}, {"text": "C", "start": 163, "end": 164, "id": 37}, {"text": ")", "start": 164, "end": 165, "id": 38}, {"text": "CT", "start": 166, "end": 168, "id": 39}, {"text": "-", "start": 168, "end": 169, "id": 40}, {"text": "guided", "start": 169, "end": 175, "id": 41}, {"text": "biopsy", "start": 176, "end": 182, "id": 42}, {"text": ".", "start": 182, "end": 183, "id": 43}, {"text": "White", "start": 184, "end": 189, "id": 44}, {"text": "arrow", "start": 190, "end": 195, "id": 45}, {"text": "=", "start": 196, "end": 197, "id": 46}, {"text": "syringe", "start": 198, "end": 205, "id": 47}, {"text": ",", "start": 205, "end": 206, "id": 48}, {"text": "black", "start": 207, "end": 212, "id": 49}, {"text": "arrow", "start": 213, "end": 218, "id": 50}, {"text": "=", "start": 219, "end": 220, "id": 51}, {"text": "exudative", "start": 221, "end": 230, "id": 52}, {"text": "area", "start": 231, "end": 235, "id": 53}, {"text": "after", "start": 236, "end": 241, "id": 54}, {"text": "injecting", "start": 242, "end": 251, "id": 55}, {"text": "2\u20133", "start": 252, "end": 255, "id": 56}, {"text": "ml", "start": 256, "end": 258, "id": 57}, {"text": "strokephysiological", "start": 259, "end": 278, "id": 58}, {"text": "saline", "start": 279, "end": 285, "id": 59}, {"text": "solution", "start": 286, "end": 294, "id": 60}, {"text": ",", "start": 294, "end": 295, "id": 61}, {"text": "white", "start": 296, "end": 301, "id": 62}, {"text": "arrowhead", "start": 302, "end": 311, "id": 63}, {"text": "=", "start": 312, "end": 313, "id": 64}, {"text": "core", "start": 314, "end": 318, "id": 65}, {"text": "needle", "start": 319, "end": 325, "id": 66}, {"text": ".", "start": 325, "end": 326, "id": 67}]}
{"pdf_hash": "d0d5d2949929e09fc148886958c5c6fd963a63ba", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig. 3. Sonograms of equine superficial gluteal muscle at D0, D2 and D7 moments. (A) D0. Region that did not received UC-MSCs/HBSS injection. Note the arrangement of the muscle fibers of a healthy tissue. (B) Needle image (yellow arrow) being guided by ultrasound at a depth of about 2 cm. (C) D2. Muscles with heterogeneous aspect (red ellipse) and presence of hypo echogenic regions (yellow arrow), after UC-MSCs injection. (D) D7. 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{"pdf_hash": "b9a91d685162e265219dfa9c503a735f62fc7738", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A male, 36-year-old patient. Non contrast-enhanced axial CT image (A) showing spontaneously hyperdense lesion located in the Monro\u00b4s foramen and in the anterior portion of the third ventricle, determining left lateral ventricle ectasia. Coronal (B) MRI and contrastenhanced, axial T1-weighted image (C) demonstrate the presence of a solid lesion with no apparent contrast uptake. On axial T2-weighted images (D) the lesion presents with isosignal. anatomopathological study revealed colloid cyst.", "width": 1048, "height": 996, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "b": [64, 65, 66, 67, 68, 69, 70, 71, 72, 46, 47, 48, 49, 50, 60, 61, 62, 63], "c": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72], "d": [73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85]}, "subfigures": [{"id": "c32bed73-d92c-4e9d-8c70-11e451b76a70", "label": "a", "points": [[4.1, 1.8], [4.1, 478.6], [441.2, 478.6], [441.2, 1.8]], "color": "yellow"}, {"id": "5abc055b-0be8-49a3-84a9-6889da03acd0", "label": "b", "points": [[442.9, 0.1], [442.9, 478.6], [1037.3, 478.6], [1037.3, 0.1]], "color": "cyan"}, {"id": "8e2b2d03-fa03-4d78-94c7-fa0a7c968f1b", "label": "c", "points": [[4.1, 486.9], [4.1, 985.2], [484.3, 985.2], [484.3, 486.9]], "color": 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{"pdf_hash": "4870f38043b0b2fe21c1af1568b20ae4da0a0f5f", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Regions of interest for optic radiation tractography. (A) Seed regions of interest were defined on an axial slice and positioned immediately lateral to the lateral geniculate nuclei within the white matter of the optic radiations at the apex of the arc around the lateral ventricles. (B) Target regions of interest were placed on a coronal slice, designed to encompass the entire white matter cross-section of the optic radiations as they passed into the primary visual cortices. (C) Optic radiation white matter tracts of a very preterm 7-year-old. 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{"pdf_hash": "4de347856cf9b8bff7d313b677f03dacd5e810cb", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (a) Pinhole-like opening in the mucosal region with scar and convergence of intestinal folds observed at the front of the endoscope. (b) No pancreatic calculi or recurrence of intraductal papillary mucinous neoplasm was noted. (c) The anastomotic site was dilated to 3 mm at 6 atm using a 4 mm balloon dilator. 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{"pdf_hash": "5d39cc664a6e9e68cad70a202081f9307863b82d", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1 Photodocumentation of pretreatment phase of one patient (case 1). a Fundus photography showing a satellite lesion (yellow square) of activ\u2011 ity suggestive of retinochoroiditis toxoplasmosis in the macula region and a healed retinochoroiditis lesion (blue circle); b fluorescein angiography showing a satellite lesion suggestive of activity of toxoplasmosis (yellow rectangle) in the macula region and a healed retinochoroiditis lesion (blue circle); c increases in the thickness of the inner retinal layers in perimacular regions (arrows) seen by optical coherence tomography", "width": 1086, "height": 1062, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "b": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 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{"pdf_hash": "9fee4c70f93604eec66fcb24e57bafcedb5039bf", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3 Ki-67 nuclear expression in different groups. Notes: Most of the nuclei showed Ki-67 nuclear immunoreactivity in control and sildenafil-treated tumors (A and B). Nuclei of cisplatin-treated tumors and tumors treated with the combination therapy showed markedly reduced nuclear Ki-67 positivity (C and D). 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{"pdf_hash": "c694caac6807edf1b15adb6538b7d7239e86aef1", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: Poorly-differentiated squamous cell carcinoma lacking clear evidence of squamous differentiation (hematoxylin and eosin) (a). In the oropharynx, these are typically HPV-associated neoplasms. Immunohistochemical stain demonstrates diffuse nuclear and cytoplasmic staining for p16 (b), while in situ hybridization highlights the presence of HPV DNA.", "width": 1370, "height": 398, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "c": [0]}, "subfigures": [{"id": "e700968c-d3cf-4dc5-b16f-0293ce19abba", "label": "a", "points": [[19.6, 1.8], [19.6, 326.5], [448.1, 326.5], [448.1, 1.8]], "color": "yellow"}, {"id": "dc3a428b-257d-471d-8dad-f463242f4b1e", "label": "b", "points": [[474.1, 1.8], [474.1, 322.1], [909.1, 322.1], [909.1, 1.8]], "color": "cyan"}, {"id": "6c8776ec-31e8-4dfa-8a86-b54674d30bef", "label": "c", "points": [[937.2, 1.8], [937.2, 320], [1367.9, 320], [1367.9, 1.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Poorly", "start": 10, "end": 16, "id": 3}, {"text": "-", "start": 16, "end": 17, "id": 4}, {"text": "differentiated", "start": 17, "end": 31, "id": 5}, {"text": "squamous", "start": 32, "end": 40, "id": 6}, {"text": "cell", "start": 41, "end": 45, "id": 7}, {"text": "carcinoma", "start": 46, "end": 55, "id": 8}, {"text": "lacking", "start": 56, "end": 63, "id": 9}, {"text": "clear", "start": 64, "end": 69, "id": 10}, {"text": "evidence", "start": 70, "end": 78, "id": 11}, {"text": "of", "start": 79, "end": 81, "id": 12}, {"text": "squamous", "start": 82, "end": 90, "id": 13}, {"text": "differentiation", "start": 91, "end": 106, "id": 14}, {"text": "(", "start": 107, "end": 108, "id": 15}, {"text": "hematoxylin", "start": 108, "end": 119, "id": 16}, {"text": "and", "start": 120, "end": 123, "id": 17}, {"text": "eosin", "start": 124, "end": 129, "id": 18}, {"text": ")", "start": 129, "end": 130, "id": 19}, {"text": "(", "start": 131, "end": 132, "id": 20}, {"text": "a", "start": 132, "end": 133, "id": 21}, {"text": ")", "start": 133, "end": 134, "id": 22}, {"text": ".", "start": 134, "end": 135, "id": 23}, {"text": "In", "start": 136, "end": 138, "id": 24}, {"text": "the", "start": 139, "end": 142, "id": 25}, {"text": "oropharynx", "start": 143, "end": 153, "id": 26}, {"text": ",", "start": 153, "end": 154, "id": 27}, {"text": "these", "start": 155, "end": 160, "id": 28}, {"text": "are", "start": 161, "end": 164, "id": 29}, {"text": "typically", "start": 165, "end": 174, "id": 30}, {"text": "HPV", "start": 175, "end": 178, "id": 31}, {"text": "-", "start": 178, "end": 179, "id": 32}, {"text": "associated", "start": 179, "end": 189, "id": 33}, {"text": "neoplasms", "start": 190, "end": 199, "id": 34}, {"text": ".", "start": 199, "end": 200, "id": 35}, {"text": "Immunohistochemical", "start": 201, "end": 220, "id": 36}, {"text": "stain", "start": 221, "end": 226, "id": 37}, {"text": "demonstrates", "start": 227, "end": 239, "id": 38}, {"text": "diffuse", "start": 240, "end": 247, "id": 39}, {"text": "nuclear", "start": 248, "end": 255, "id": 40}, {"text": "and", "start": 256, "end": 259, "id": 41}, {"text": "cytoplasmic", "start": 260, "end": 271, "id": 42}, {"text": "staining", "start": 272, "end": 280, "id": 43}, {"text": "for", "start": 281, "end": 284, "id": 44}, {"text": "p16", "start": 285, "end": 288, "id": 45}, {"text": "(", "start": 289, "end": 290, "id": 46}, {"text": "b", "start": 290, "end": 291, "id": 47}, {"text": ")", "start": 291, "end": 292, "id": 48}, {"text": ",", "start": 292, "end": 293, "id": 49}, {"text": "while", "start": 294, "end": 299, "id": 50}, {"text": "in", "start": 300, "end": 302, "id": 51}, {"text": "situ", "start": 303, "end": 307, "id": 52}, {"text": "hybridization", "start": 308, "end": 321, "id": 53}, {"text": "highlights", "start": 322, "end": 332, "id": 54}, {"text": "the", "start": 333, "end": 336, "id": 55}, {"text": "presence", "start": 337, "end": 345, "id": 56}, {"text": "of", "start": 346, "end": 348, "id": 57}, {"text": "HPV", "start": 349, "end": 352, "id": 58}, {"text": "DNA", "start": 353, "end": 356, "id": 59}, {"text": ".", "start": 356, "end": 357, "id": 60}]}
{"pdf_hash": "93b7fdd08a4b2716d65ad135b04d13ec67951154", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 a, b Ewing sarcoma of the liver in a 10-year-old boy. a Axial abdominal CT shows a large, predominantly hypodense tumor involving the right lobe. The inferior vena cava (arrows) is compressed and displaced by the tumor and appears elongated in the anteroposterior direction. b Coronal reformatted abdominal CT image shows the spatial relationship between the tumor and adjacent structures such as the inferior vena cava (asterisks) and right kidney (arrows)", "width": 1042, "height": 478, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86]}, "subfigures": [{"id": "8488122f-c5df-4b89-81a1-9420ba28dec5", "label": "a", "points": [[29.6, 26.3], [29.6, 472.4], [541.6, 472.4], [541.6, 26.3]], "color": "yellow"}, {"id": "708e4414-d6cd-499f-a03d-f6f7f2a1d68b", "label": "b", "points": [[554.8, 28], [554.8, 472.4], [1033.8, 472.4], [1033.8, 28]], "color": "cyan"}], "tokens": [{"text": "Fig", 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{"pdf_hash": "9bc37668136348b58a6b07bc3e4a88dfc1f01fee", "fig_key": "Figure8", "fig_uri": "6-Figure8-1.png", "text": "Figure 8. Micro-computed tomography images of the cross-section of the magnesium pin (week 36). (A) Maximum inner diameter of the new bone loop (orange line, 2.34 mm) and (B) Diameter of the pin (orange line, 1.94 mm) at the same position. 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{"pdf_hash": "ee36b5d28724c2ba693b511e86d18d7875a0f757", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "FIG. 2. Sarcomeric organization of RyR clusters in developing mouse diaphragm. Immunofluorescence labeling of RyRs shows the first yR clusters at E15 at or close to the periphery of individual myotubes (arrows, A). Some clusters are also present internally (double arrows) ut show no regular organization. At E16, strings of RyRs clusters are detected throughout the myotubes (B). In some areas, the clusters re in doublets (double arrows) that have a two-per-sarcomere spacing and are transversely aligned across several adjacent myofibrillar undles. However, a less ordered arrangement is also often seen at this age. At E17, the majority of RyR clusters are arranged in doublets nd in obvious transverse bands (C). While this general arrangement persists throughout development, the doublets of RyR clusters become ore discrete, denser, and better aligned with age (D\u2013F). 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{"pdf_hash": "52b71a0bffd18d07134418ad88c8fcbc20a4256b", "fig_key": "Figure3", "fig_uri": "11-Figure3-1.png", "text": "FIG. 3. Color online Anatomopathological findings in asbestos related diseases. A Chest x ray in the case of asbestosis benign disease with plaques on diaphragmatic and mediastinal pleura. Pleural plaques are localized scars fibrosis consisting of collagen fiber deposits that form as a result of exposure to asbestos. They are the most common manifestation of exposure to asbestos. Normally, pleural plaque is found in the parietal pleura on the inside of the diaphragm , but in very rare cases, they can also be found near the ribcage. Asbestosis is a chronic inflammatory and fibrotic medical condition affecting the parenchymal tissue of the lungs caused by the inhalation and retention of asbestos fibers. It specifically refers to interstitial parenchymal fibrosis from asbestos, and not pleural fibrosis or plaguing. B Asbestos bodies found in sputum. Asbestos bodies are constituted of a central asbestos fiber surrounded by a lining of iron and proteins, which is often segmented. They have a median width of 2.5 m and a median length of 20\u201350 m and generally have a straight shape. C and D Thoracic CT scan\u2014trasversal C and coronal D sections in MPM, showing the thickening of both parietal and visceral pleural layers. E and F Proliferative epithelioid mesothelioma, chest x rays E and the corresponding thoracoscopy view F ; black arrow \u2192 indicates malignant areas, while the white one \u21d2 denotes an isolated hyaline plate. Hyaline pleural plaques generally occur as discrete elevated gray-white areas, usually involving the parietal layer and without associated effusions or adhesions. They are composed of laminated hyaline collagen; there is no suggestion of vasculature or granulation. They are usually detected in the case of asbestos exposure. Thoracoscopy is a medical procedure involving internal examination, biopsy, and/or resection of disease or masses within the pleural cavity and thoracic cavity. It is the golden standard procedure for MPM diagnosis. Courtesy of E. Pozzi and P. Cremaschi, Cardio-Thoraco Vascular Dept., Section of Pneumology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.", "width": 666, "height": 770, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138], "b": [139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190], "c": [191, 194, 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{"pdf_hash": "8deb3af20cf5b5b1381c74d3b72f635374fa8b0e", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 a Seven months after extraction of tooth #47, a panoramic radiograph showed new bone formation at the equivalent site of teeth #48 and #47 and a radiolucent region around the distal root of tooth #46. b, c Computed tomography showed continuous absorption from the alveolar bone of the distal root of tooth #46 to the lingual cortical bone at the equivalent of tooth #47 and some granulated hard tissues existing inside and outside the mandible (arrow). d Magnetic resonance imaging showed high intensity of the right lower molar region on an enhanced T2-weighted image (arrow). e The soft tissue located between interior to the mandibular angle and anterior to the submandibular gland was enhanced heterogeneously by gadolinium on magnetic resonance imaging (arrow). 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{"pdf_hash": "0b9f83f94b0d48d3013ea17926cabdb853308b84", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. In vivo assessment of renal perfusion by MRI 3 weeks following RAS surgery. (a) Representative axial cross sectional MR image of the stenotic and contralateral kidney. (b) Representative perfusion map of renal cortex and medulla. (c) Assessment of renal perfusion at baseline and following RAS surgery. 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{"pdf_hash": "b92a401116247679a580bd96b1ca588d5290d91e", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Magnetic resonance images of the thalamus representing 3 orthogonal orientations displayed with MEASURE software. A, Coronal plane; B, sagittal plane; and C, horizontal plane. Grid points falling within the anatomic boundaries of the thalamus are black instead of white.", "width": 634, "height": 1226, "subcaptions": {"a": [18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27], "c": [29, 30, 31, 32, 33]}, "subfigures": [{"id": "6657565c-5621-42b7-be75-05c9547d1a39", "label": "a", "points": [[4.5, 3.8], [4.5, 395.4], [629.5, 395.4], [629.5, 3.8]], "color": "yellow"}, {"id": "c0cffb5e-7106-43dc-891d-bc21916fc9df", "label": "b", "points": [[7.6, 414.5], [7.6, 780], [632.5, 780], [632.5, 414.5]], "color": "cyan"}, {"id": "89dee1b3-7db2-4daf-8b6a-c43e33cbba97", "label": "c", "points": [[3.5, 795], [3.5, 1199.7], [630.5, 1199.7], [630.5, 795]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Magnetic", "start": 10, "end": 18, "id": 3}, {"text": "resonance", "start": 19, "end": 28, "id": 4}, {"text": "images", "start": 29, "end": 35, "id": 5}, {"text": "of", "start": 36, "end": 38, "id": 6}, {"text": "the", "start": 39, "end": 42, "id": 7}, {"text": "thalamus", "start": 43, "end": 51, "id": 8}, {"text": "representing", "start": 52, "end": 64, "id": 9}, {"text": "3", "start": 65, "end": 66, "id": 10}, {"text": "orthogonal", "start": 67, "end": 77, "id": 11}, {"text": "orientations", "start": 78, "end": 90, "id": 12}, {"text": "displayed", "start": 91, "end": 100, "id": 13}, {"text": "with", "start": 101, "end": 105, "id": 14}, {"text": "MEASURE", "start": 106, "end": 113, "id": 15}, {"text": "software", "start": 114, "end": 122, "id": 16}, {"text": ".", "start": 122, "end": 123, "id": 17}, {"text": "A", "start": 124, "end": 125, "id": 18}, {"text": ",", "start": 125, "end": 126, "id": 19}, {"text": "Coronal", "start": 127, "end": 134, "id": 20}, {"text": "plane", "start": 135, "end": 140, "id": 21}, {"text": ";", "start": 140, "end": 141, "id": 22}, {"text": "B", "start": 142, "end": 143, "id": 23}, {"text": ",", "start": 143, "end": 144, "id": 24}, {"text": "sagittal", "start": 145, "end": 153, "id": 25}, {"text": "plane", "start": 154, "end": 159, "id": 26}, {"text": ";", "start": 159, "end": 160, "id": 27}, {"text": "and", "start": 161, "end": 164, "id": 28}, {"text": "C", "start": 165, "end": 166, "id": 29}, {"text": ",", "start": 166, "end": 167, "id": 30}, {"text": "horizontal", "start": 168, "end": 178, "id": 31}, {"text": "plane", "start": 179, "end": 184, "id": 32}, {"text": ".", "start": 184, "end": 185, "id": 33}, {"text": "Grid", "start": 186, "end": 190, "id": 34}, {"text": "points", "start": 191, "end": 197, "id": 35}, {"text": "falling", "start": 198, "end": 205, "id": 36}, {"text": "within", "start": 206, "end": 212, "id": 37}, {"text": "the", "start": 213, "end": 216, "id": 38}, {"text": "anatomic", "start": 217, "end": 225, "id": 39}, {"text": "boundaries", "start": 226, "end": 236, "id": 40}, {"text": "of", "start": 237, "end": 239, "id": 41}, {"text": "the", "start": 240, "end": 243, "id": 42}, {"text": "thalamus", "start": 244, "end": 252, "id": 43}, {"text": "are", "start": 253, "end": 256, "id": 44}, {"text": "black", "start": 257, "end": 262, "id": 45}, {"text": "instead", "start": 263, "end": 270, "id": 46}, {"text": "of", "start": 271, "end": 273, "id": 47}, {"text": "white", "start": 274, "end": 279, "id": 48}, {"text": ".", "start": 279, "end": 280, "id": 49}]}
{"pdf_hash": "cc3c2e3daf866357211e56a3140e6b58d40cda4a", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig 1. A segmental upper lobe consolidation: a) Chest X ray reveals an opacity in the right upper lobe (well delimited by horizontal fissure); b) Ultrasound performed at the level of the axilla shows a \u201ctissular\u201d pattern of the consolidated segment with vessels inside. In depth there is an irregular border (shred sign), the transition between consolidation and the normal aerated lung", "width": 632, "height": 348, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53]}, "subfigures": [{"id": "01b0ebfc-407b-4bb8-951e-6410ed0bc858", "label": "a", "points": [[2, 0.8], [2, 311.9], [322, 311.9], [322, 0.8]], "color": "yellow"}, {"id": "e334bd5f-bae0-4261-bcea-1d1b791834af", "label": "b", "points": [[330, 1.8], [330, 310.9], [630.1, 310.9], [630.1, 1.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "1", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "segmental", "start": 9, "end": 18, "id": 4}, {"text": "upper", "start": 19, "end": 24, "id": 5}, {"text": "lobe", "start": 25, "end": 29, "id": 6}, {"text": "consolidation", "start": 30, "end": 43, "id": 7}, {"text": ":", "start": 43, "end": 44, "id": 8}, {"text": "a", "start": 45, "end": 46, "id": 9}, {"text": ")", "start": 46, "end": 47, "id": 10}, {"text": "Chest", "start": 48, "end": 53, "id": 11}, {"text": "X", "start": 54, "end": 55, "id": 12}, {"text": "ray", "start": 56, "end": 59, "id": 13}, {"text": "reveals", "start": 60, "end": 67, "id": 14}, {"text": "an", "start": 68, "end": 70, "id": 15}, {"text": "opacity", "start": 71, "end": 78, "id": 16}, {"text": "in", "start": 79, "end": 81, "id": 17}, {"text": "the", "start": 82, "end": 85, "id": 18}, {"text": "right", "start": 86, "end": 91, "id": 19}, {"text": "upper", "start": 92, "end": 97, "id": 20}, {"text": "lobe", "start": 98, "end": 102, "id": 21}, {"text": "(", "start": 103, "end": 104, "id": 22}, {"text": "well", "start": 104, "end": 108, "id": 23}, {"text": "delimited", "start": 109, "end": 118, "id": 24}, {"text": "by", "start": 119, "end": 121, "id": 25}, {"text": "horizontal", "start": 122, "end": 132, "id": 26}, {"text": "fissure", "start": 133, "end": 140, "id": 27}, {"text": ")", "start": 140, "end": 141, "id": 28}, {"text": ";", "start": 141, "end": 142, "id": 29}, {"text": "b", "start": 143, "end": 144, "id": 30}, {"text": ")", "start": 144, "end": 145, "id": 31}, {"text": "Ultrasound", "start": 146, "end": 156, "id": 32}, {"text": "performed", "start": 157, "end": 166, "id": 33}, {"text": "at", "start": 167, "end": 169, "id": 34}, {"text": "the", "start": 170, "end": 173, "id": 35}, {"text": "level", "start": 174, "end": 179, "id": 36}, {"text": "of", "start": 180, "end": 182, "id": 37}, {"text": "the", "start": 183, "end": 186, "id": 38}, {"text": "axilla", "start": 187, "end": 193, "id": 39}, {"text": "shows", "start": 194, "end": 199, "id": 40}, {"text": "a", "start": 200, "end": 201, "id": 41}, {"text": "\u201c", "start": 202, "end": 203, "id": 42}, {"text": "tissular", "start": 203, "end": 211, "id": 43}, {"text": "\u201d", "start": 211, "end": 212, "id": 44}, {"text": "pattern", "start": 213, "end": 220, "id": 45}, {"text": "of", "start": 221, "end": 223, "id": 46}, {"text": "the", "start": 224, "end": 227, "id": 47}, {"text": "consolidated", "start": 228, "end": 240, "id": 48}, {"text": "segment", "start": 241, "end": 248, "id": 49}, {"text": "with", "start": 249, "end": 253, "id": 50}, {"text": "vessels", "start": 254, "end": 261, "id": 51}, {"text": "inside", "start": 262, "end": 268, "id": 52}, {"text": ".", "start": 268, "end": 269, "id": 53}, {"text": "In", "start": 270, "end": 272, "id": 54}, {"text": "depth", "start": 273, "end": 278, "id": 55}, {"text": "there", "start": 279, "end": 284, "id": 56}, {"text": "is", "start": 285, "end": 287, "id": 57}, {"text": "an", "start": 288, "end": 290, "id": 58}, {"text": "irregular", "start": 291, "end": 300, "id": 59}, {"text": "border", "start": 301, "end": 307, "id": 60}, {"text": "(", "start": 308, "end": 309, "id": 61}, {"text": "shred", "start": 309, "end": 314, "id": 62}, {"text": "sign", "start": 315, "end": 319, "id": 63}, {"text": ")", "start": 319, "end": 320, "id": 64}, {"text": ",", "start": 320, "end": 321, "id": 65}, {"text": "the", "start": 322, "end": 325, "id": 66}, {"text": "transition", "start": 326, "end": 336, "id": 67}, {"text": "between", "start": 337, "end": 344, "id": 68}, {"text": "consolidation", "start": 345, "end": 358, "id": 69}, {"text": "and", "start": 359, "end": 362, "id": 70}, {"text": "the", "start": 363, "end": 366, "id": 71}, {"text": "normal", "start": 367, "end": 373, "id": 72}, {"text": "aerated", "start": 374, "end": 381, "id": 73}, {"text": "lung", "start": 382, "end": 386, "id": 74}]}
{"pdf_hash": "c538055bc8f73f103a819e7785a297245e2e4997", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. The setting of different regions of interest (ROIs). Hounsfield value (HU) represent the CT value used to calculate the CNR and deviation (DEV) represent the standard deviation (SD) value also used in the same formula. Unilateral settings in the small FOV (A) and bilaterally in the large FOV (B).", "width": 612, "height": 1204, "subcaptions": {"a": [49, 50, 51, 52, 53, 54, 55, 56, 57], "b": [58, 59, 60, 61, 62, 63, 64, 65, 66, 67]}, "subfigures": [{"id": "4bf530d8-c919-45f8-8058-ee8357b55fb6", "label": "a", "points": [[13, 0.7], [13, 587.7], [611, 587.7], [611, 0.7]], "color": "yellow"}, {"id": "4cd1e444-761e-43fd-a49d-f50697bebb1a", "label": "b", "points": [[13, 611], [13, 1178], [610, 1178], [610, 611]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "The", "start": 8, "end": 11, "id": 4}, {"text": "setting", "start": 12, "end": 19, "id": 5}, {"text": "of", "start": 20, "end": 22, "id": 6}, {"text": "different", "start": 23, "end": 32, "id": 7}, {"text": "regions", "start": 33, "end": 40, "id": 8}, {"text": "of", "start": 41, "end": 43, "id": 9}, {"text": "interest", "start": 44, "end": 52, "id": 10}, {"text": "(", "start": 53, "end": 54, "id": 11}, {"text": "ROIs", "start": 54, "end": 58, "id": 12}, {"text": ")", "start": 58, "end": 59, "id": 13}, {"text": ".", "start": 59, "end": 60, "id": 14}, {"text": "Hounsfield", "start": 61, "end": 71, "id": 15}, {"text": "value", "start": 72, "end": 77, "id": 16}, {"text": "(", "start": 78, "end": 79, "id": 17}, {"text": "HU", "start": 79, "end": 81, "id": 18}, {"text": ")", "start": 81, "end": 82, "id": 19}, {"text": "represent", "start": 83, "end": 92, "id": 20}, {"text": "the", "start": 93, "end": 96, "id": 21}, {"text": "CT", "start": 97, "end": 99, "id": 22}, {"text": "value", "start": 100, "end": 105, "id": 23}, {"text": "used", "start": 106, "end": 110, "id": 24}, {"text": "to", "start": 111, "end": 113, "id": 25}, {"text": "calculate", "start": 114, "end": 123, "id": 26}, {"text": "the", "start": 124, "end": 127, "id": 27}, {"text": "CNR", "start": 128, "end": 131, "id": 28}, {"text": "and", "start": 132, "end": 135, "id": 29}, {"text": "deviation", "start": 136, "end": 145, "id": 30}, {"text": "(", "start": 146, "end": 147, "id": 31}, {"text": "DEV", "start": 147, "end": 150, "id": 32}, {"text": ")", "start": 150, "end": 151, "id": 33}, {"text": "represent", "start": 152, "end": 161, "id": 34}, {"text": "the", "start": 162, "end": 165, "id": 35}, {"text": "standard", "start": 166, "end": 174, "id": 36}, {"text": "deviation", "start": 175, "end": 184, "id": 37}, {"text": "(", "start": 185, "end": 186, "id": 38}, {"text": "SD", "start": 186, "end": 188, "id": 39}, {"text": ")", "start": 188, "end": 189, "id": 40}, {"text": "value", "start": 190, "end": 195, "id": 41}, {"text": "also", "start": 196, "end": 200, "id": 42}, {"text": "used", "start": 201, "end": 205, "id": 43}, {"text": "in", "start": 206, "end": 208, "id": 44}, {"text": "the", "start": 209, "end": 212, "id": 45}, {"text": "same", "start": 213, "end": 217, "id": 46}, {"text": "formula", "start": 218, "end": 225, "id": 47}, {"text": ".", "start": 225, "end": 226, "id": 48}, {"text": "Unilateral", "start": 227, "end": 237, "id": 49}, {"text": "settings", "start": 238, "end": 246, "id": 50}, {"text": "in", "start": 247, "end": 249, "id": 51}, {"text": "the", "start": 250, "end": 253, "id": 52}, {"text": "small", "start": 254, "end": 259, "id": 53}, {"text": "FOV", "start": 260, "end": 263, "id": 54}, {"text": "(", "start": 264, "end": 265, "id": 55}, {"text": "A", "start": 265, "end": 266, "id": 56}, {"text": ")", "start": 266, "end": 267, "id": 57}, {"text": "and", "start": 268, "end": 271, "id": 58}, {"text": "bilaterally", "start": 272, "end": 283, "id": 59}, {"text": "in", "start": 284, "end": 286, "id": 60}, {"text": "the", "start": 287, "end": 290, "id": 61}, {"text": "large", "start": 291, "end": 296, "id": 62}, {"text": "FOV", "start": 297, "end": 300, "id": 63}, {"text": "(", "start": 301, "end": 302, "id": 64}, {"text": "B", "start": 302, "end": 303, "id": 65}, {"text": ")", "start": 303, "end": 304, "id": 66}, {"text": ".", "start": 304, "end": 305, "id": 67}]}
{"pdf_hash": "f57dc1b91eb5b127a92761c6d9daef64bed9578f", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1 Epidermal thickness (ET) measurement procedure by HighDefinition Optical Coherence Tomography 3-D imaging: (a) Crosssectional (CS) mode and (b) En-face (EF) mode. Each voxel of the 3-D HD-OCT imaging is defined by a unique set of x, y, z coordinates. (1) First the basal cell layer at the suprapapillary plate will be searched for in the EF mode at the cross of green and red line (yellow arrow \u2018\u20181\u2019\u2019). (2) The exact position of the basal cell layer in the CS mode can be determined at the cross of green and blue line (yellow arrow \u2018\u20182\u2019\u2019). 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{"pdf_hash": "34e43c3905e6fac2ffc065f21079741ce569a09a", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Figure 6. Diverticulitis with a giant diverticulum mimicking a perisigmoid abscess: a, b: axial and sagittal slices: image of air content (star), with an air-fluid level (arrow), attached to the sigmoid colon; c: sagittal slice: after antibiotic treatment air persists (star) communicating with the lumen of the sigmoid colon (arrow).", "width": 1374, "height": 568, "subcaptions": {"a": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70]}, "subfigures": [{"id": "1a893acf-2f1d-481f-8a6d-13ba7b960164", "label": "a", "points": [[9, 9.4], [9, 530.4], [484.4, 530.4], [484.4, 9.4]], "color": "yellow"}, {"id": "befe1144-9e78-4e04-bb2e-60ad020e9c69", "label": "a", "points": [[501.8, 5.1], [501.8, 521.7], [883.8, 521.7], [883.8, 5.1]], "color": "magenta"}, {"id": "0586e0c0-8065-4198-8378-c61f9c59b503", "label": "b", "points": [[909.9, 11.6], [909.9, 521.7], [1370.1, 521.7], [1370.1, 11.6]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Diverticulitis", "start": 10, "end": 24, "id": 3}, {"text": "with", "start": 25, "end": 29, "id": 4}, {"text": "a", "start": 30, "end": 31, "id": 5}, {"text": "giant", "start": 32, "end": 37, "id": 6}, {"text": "diverticulum", "start": 38, "end": 50, "id": 7}, {"text": "mimicking", "start": 51, "end": 60, "id": 8}, {"text": "a", "start": 61, "end": 62, "id": 9}, {"text": "perisigmoid", "start": 63, "end": 74, "id": 10}, {"text": "abscess", "start": 75, "end": 82, "id": 11}, {"text": ":", "start": 82, "end": 83, "id": 12}, {"text": "a", "start": 84, "end": 85, "id": 13}, {"text": ",", "start": 85, "end": 86, "id": 14}, {"text": "b", "start": 87, "end": 88, "id": 15}, {"text": ":", "start": 88, "end": 89, "id": 16}, {"text": "axial", "start": 90, "end": 95, "id": 17}, {"text": "and", "start": 96, "end": 99, "id": 18}, {"text": "sagittal", "start": 100, "end": 108, "id": 19}, {"text": "slices", "start": 109, "end": 115, "id": 20}, {"text": ":", "start": 115, "end": 116, "id": 21}, {"text": "image", "start": 117, "end": 122, "id": 22}, {"text": "of", "start": 123, "end": 125, "id": 23}, {"text": "air", "start": 126, "end": 129, "id": 24}, {"text": "content", "start": 130, "end": 137, "id": 25}, {"text": "(", "start": 138, "end": 139, "id": 26}, {"text": "star", "start": 139, "end": 143, "id": 27}, {"text": ")", "start": 143, "end": 144, "id": 28}, {"text": ",", "start": 144, "end": 145, "id": 29}, {"text": "with", "start": 146, "end": 150, "id": 30}, {"text": "an", "start": 151, "end": 153, "id": 31}, {"text": "air", "start": 154, "end": 157, "id": 32}, {"text": "-", "start": 157, "end": 158, "id": 33}, {"text": "fluid", "start": 158, "end": 163, "id": 34}, {"text": "level", "start": 164, "end": 169, "id": 35}, {"text": "(", "start": 170, "end": 171, "id": 36}, {"text": "arrow", "start": 171, "end": 176, "id": 37}, {"text": ")", "start": 176, "end": 177, "id": 38}, {"text": ",", "start": 177, "end": 178, "id": 39}, {"text": "attached", "start": 179, "end": 187, "id": 40}, {"text": "to", "start": 188, "end": 190, "id": 41}, {"text": "the", "start": 191, "end": 194, "id": 42}, {"text": "sigmoid", "start": 195, "end": 202, "id": 43}, {"text": "colon", "start": 203, "end": 208, "id": 44}, {"text": ";", "start": 208, "end": 209, "id": 45}, {"text": "c", "start": 210, "end": 211, "id": 46}, {"text": ":", "start": 211, "end": 212, "id": 47}, {"text": "sagittal", "start": 213, "end": 221, "id": 48}, {"text": "slice", "start": 222, "end": 227, "id": 49}, {"text": ":", "start": 227, "end": 228, "id": 50}, {"text": "after", "start": 229, "end": 234, "id": 51}, {"text": "antibiotic", "start": 235, "end": 245, "id": 52}, {"text": "treatment", "start": 246, "end": 255, "id": 53}, {"text": "air", "start": 256, "end": 259, "id": 54}, {"text": "persists", "start": 260, "end": 268, "id": 55}, {"text": "(", "start": 269, "end": 270, "id": 56}, {"text": "star", "start": 270, "end": 274, "id": 57}, {"text": ")", "start": 274, "end": 275, "id": 58}, {"text": "communicating", "start": 276, "end": 289, "id": 59}, {"text": "with", "start": 290, "end": 294, "id": 60}, {"text": "the", "start": 295, "end": 298, "id": 61}, {"text": "lumen", "start": 299, "end": 304, "id": 62}, {"text": "of", "start": 305, "end": 307, "id": 63}, {"text": "the", "start": 308, "end": 311, "id": 64}, {"text": "sigmoid", "start": 312, "end": 319, "id": 65}, {"text": "colon", "start": 320, "end": 325, "id": 66}, {"text": "(", "start": 326, "end": 327, "id": 67}, {"text": "arrow", "start": 327, "end": 332, "id": 68}, {"text": ")", "start": 332, "end": 333, "id": 69}, {"text": ".", "start": 333, "end": 334, "id": 70}]}
{"pdf_hash": "d5c9d0eb9a3d107fedb0b5501976cb70322ad0ec", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Immunohistochemical staining in islets from patients with nesidioblastosis (a, c, e), and control islets (b, d, f ). (a) IGF2 staining shows 3 \u00fe immunostaining in a postgastric bypass nesidioblastosis case. The islet is irregular with hypertrophied cells. There is moderate nuclear pleomorphism. (b) IGF2 is in a control islet showing 1 \u00fe staining intensity. (c) IGF1Ra showing a postgastric bypass nesidioblastosis case. The islet cells are hypertrophied, and there is 2 \u00fe staining, which is predominantly cell membrane staining. (d) Control islet with 1 \u00fe staining in a control case. (e) TGFbR3 immunostaining in a postgastric bypass islet showing 2 \u00fe staining in the hypertrophied islet cells. The staining is predominantly cytoplasmic with focal cell membrane staining. (f) Control islet showing weaker 1 \u00fe staining for TGFbR3. 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{"pdf_hash": "a6262f4b46b9988dfab1e58060bdce6b6a66ae4e", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 CT and MRI images of the mandibular region (scale bar, 5 cm). a A CT image showing a solid mass in the medial mandibular gingiva with bone destruction. b An MRI image showing a heterogeneous signal on a T1-weighted image after gadolinium administration", "width": 856, "height": 440, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50]}, "subfigures": [{"id": "8f2f9af8-74e5-41b0-a3a7-4d47ca1b6380", "label": "a", "points": [[39.9, 20.3], [39.9, 408.4], [422.6, 408.4], [422.6, 20.3]], "color": "yellow"}, {"id": "ab8e9349-17a5-4446-b9cb-7186fd3d0c1a", "label": "b", "points": [[440.2, 24.3], [440.2, 407.1], [817.5, 407.1], [817.5, 24.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "CT", "start": 7, "end": 9, "id": 3}, {"text": "and", "start": 10, "end": 13, "id": 4}, {"text": "MRI", "start": 14, "end": 17, "id": 5}, {"text": "images", "start": 18, "end": 24, "id": 6}, {"text": "of", "start": 25, "end": 27, "id": 7}, {"text": "the", "start": 28, "end": 31, "id": 8}, {"text": "mandibular", "start": 32, "end": 42, "id": 9}, {"text": "region", "start": 43, "end": 49, "id": 10}, {"text": "(", "start": 50, "end": 51, "id": 11}, {"text": "scale", "start": 51, "end": 56, "id": 12}, {"text": "bar", "start": 57, "end": 60, "id": 13}, {"text": ",", "start": 60, "end": 61, "id": 14}, {"text": "5", "start": 62, "end": 63, "id": 15}, {"text": "cm", "start": 64, "end": 66, "id": 16}, {"text": ")", "start": 66, "end": 67, "id": 17}, {"text": ".", "start": 67, "end": 68, "id": 18}, {"text": "a", "start": 69, "end": 70, "id": 19}, {"text": "A", "start": 71, "end": 72, "id": 20}, {"text": "CT", "start": 73, "end": 75, "id": 21}, {"text": "image", "start": 76, "end": 81, "id": 22}, {"text": "showing", "start": 82, "end": 89, "id": 23}, {"text": "a", "start": 90, "end": 91, "id": 24}, {"text": "solid", "start": 92, "end": 97, "id": 25}, {"text": "mass", "start": 98, "end": 102, "id": 26}, {"text": "in", "start": 103, "end": 105, "id": 27}, {"text": "the", "start": 106, "end": 109, "id": 28}, {"text": "medial", "start": 110, "end": 116, "id": 29}, {"text": "mandibular", "start": 117, "end": 127, "id": 30}, {"text": "gingiva", "start": 128, "end": 135, "id": 31}, {"text": "with", "start": 136, "end": 140, "id": 32}, {"text": "bone", "start": 141, "end": 145, "id": 33}, {"text": "destruction", "start": 146, "end": 157, "id": 34}, {"text": ".", "start": 157, "end": 158, "id": 35}, {"text": "b", "start": 159, "end": 160, "id": 36}, {"text": "An", "start": 161, "end": 163, "id": 37}, {"text": "MRI", "start": 164, "end": 167, "id": 38}, {"text": "image", "start": 168, "end": 173, "id": 39}, {"text": "showing", "start": 174, "end": 181, "id": 40}, {"text": "a", "start": 182, "end": 183, "id": 41}, {"text": "heterogeneous", "start": 184, "end": 197, "id": 42}, {"text": "signal", "start": 198, "end": 204, "id": 43}, {"text": "on", "start": 205, "end": 207, "id": 44}, {"text": "a", "start": 208, "end": 209, "id": 45}, {"text": "T1-weighted", "start": 210, "end": 221, "id": 46}, {"text": "image", "start": 222, "end": 227, "id": 47}, {"text": "after", "start": 228, "end": 233, "id": 48}, {"text": "gadolinium", "start": 234, "end": 244, "id": 49}, {"text": "administration", "start": 245, "end": 259, "id": 50}]}
{"pdf_hash": "5f0fcae89018b0662084d33ac68d5deb733db12d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 This is a schematic depicting a typical workflow from imaging to physical part. A sample is imaged. The raw images need to be analyzed and a model needs to be created from them. The model can be edited using some of the software described in this paper before a final part is fabricated", "width": 1008, "height": 428, "subcaptions": {"a": [0]}, "subfigures": [{"id": "f23eb333-ef75-47c6-bdd3-fbb9a1aa2f36", "label": "a", "points": [[27.3, 38.7], [27.3, 180.5], [259.8, 180.5], [259.8, 38.7]], "color": "yellow"}, {"id": "aa2d4753-5408-4c17-b1c3-6e1d95effc7b", "label": "b", "points": [[25.7, 191.6], [25.7, 319], [263, 319], [263, 191.6]], "color": "cyan"}, {"id": "b5269d15-4399-4980-b160-73005973e791", "label": "c", "points": [[266.2, 186.8], [266.2, 320.6], [490.7, 320.6], [490.7, 186.8]], "color": "magenta"}, {"id": "49c81153-de5d-43e5-89ee-df2d2115ff53", "label": "d", "points": [[505.1, 186.8], [505.1, 322.2], [737.6, 322.2], [737.6, 186.8]], "color": "springgreen"}, {"id": "4b0ea32d-1512-46d6-82fd-d5c46ff999be", "label": "e", "points": [[743.9, 180.5], [743.9, 333.3], [968.5, 333.3], [968.5, 180.5]], "color": "tomato"}, {"id": "46f5b178-765a-4e2a-8a52-f32603cc0f5a", "label": "f", "points": [[745.5, 32.4], [745.5, 178.9], [968.5, 178.9], [968.5, 32.4]], "color": "deepskyblue"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "This", "start": 7, "end": 11, "id": 3}, {"text": "is", "start": 12, "end": 14, "id": 4}, {"text": "a", "start": 15, "end": 16, "id": 5}, {"text": "schematic", "start": 17, "end": 26, "id": 6}, {"text": "depicting", "start": 27, "end": 36, "id": 7}, {"text": "a", "start": 37, "end": 38, "id": 8}, {"text": "typical", "start": 39, "end": 46, "id": 9}, {"text": "workflow", "start": 47, "end": 55, "id": 10}, {"text": "from", "start": 56, "end": 60, "id": 11}, {"text": "imaging", "start": 61, "end": 68, "id": 12}, {"text": "to", "start": 69, "end": 71, "id": 13}, {"text": "physical", "start": 72, "end": 80, "id": 14}, {"text": "part", "start": 81, "end": 85, "id": 15}, {"text": ".", "start": 85, "end": 86, "id": 16}, {"text": "A", "start": 87, "end": 88, "id": 17}, {"text": "sample", "start": 89, "end": 95, "id": 18}, {"text": "is", "start": 96, "end": 98, "id": 19}, {"text": "imaged", "start": 99, "end": 105, "id": 20}, {"text": ".", "start": 105, "end": 106, "id": 21}, {"text": "The", "start": 107, "end": 110, "id": 22}, {"text": "raw", "start": 111, "end": 114, "id": 23}, {"text": "images", "start": 115, "end": 121, "id": 24}, {"text": "need", "start": 122, "end": 126, "id": 25}, {"text": "to", "start": 127, "end": 129, "id": 26}, {"text": "be", "start": 130, "end": 132, "id": 27}, {"text": "analyzed", "start": 133, "end": 141, "id": 28}, {"text": "and", "start": 142, "end": 145, "id": 29}, {"text": "a", "start": 146, "end": 147, "id": 30}, {"text": "model", "start": 148, "end": 153, "id": 31}, {"text": "needs", "start": 154, "end": 159, "id": 32}, {"text": "to", "start": 160, "end": 162, "id": 33}, {"text": "be", "start": 163, "end": 165, "id": 34}, {"text": "created", "start": 166, "end": 173, "id": 35}, {"text": "from", "start": 174, "end": 178, "id": 36}, {"text": "them", "start": 179, "end": 183, "id": 37}, {"text": ".", "start": 183, "end": 184, "id": 38}, {"text": "The", "start": 185, "end": 188, "id": 39}, {"text": "model", "start": 189, "end": 194, "id": 40}, {"text": "can", "start": 195, "end": 198, "id": 41}, {"text": "be", "start": 199, "end": 201, "id": 42}, {"text": "edited", "start": 202, "end": 208, "id": 43}, {"text": "using", "start": 209, "end": 214, "id": 44}, {"text": "some", "start": 215, "end": 219, "id": 45}, {"text": "of", "start": 220, "end": 222, "id": 46}, {"text": "the", "start": 223, "end": 226, "id": 47}, {"text": "software", "start": 227, "end": 235, "id": 48}, {"text": "described", "start": 236, "end": 245, "id": 49}, {"text": "in", "start": 246, "end": 248, "id": 50}, {"text": "this", "start": 249, "end": 253, "id": 51}, {"text": "paper", "start": 254, "end": 259, "id": 52}, {"text": "before", "start": 260, "end": 266, "id": 53}, {"text": "a", "start": 267, "end": 268, "id": 54}, {"text": "final", "start": 269, "end": 274, "id": 55}, {"text": "part", "start": 275, "end": 279, "id": 56}, {"text": "is", "start": 280, "end": 282, "id": 57}, {"text": "fabricated", "start": 283, "end": 293, "id": 58}]}
{"pdf_hash": "4bf27394e05d062e9dd06389ed5b1e412c24518f", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Intraoperative endoscopic views of the transsphenoidal approach. A, Coronal computed tomography section shows a vidian canal with canal floor type 1. B, The vidian canal can be visualized at the floor of the sphenoid sinus. C, A probe is used to transect the vidian canal. D, Successful transection of the vidian nerve is performed by direct vision. 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{"pdf_hash": "9d66a75d29694211facf38cb1219e54d54eb8a9d", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig. 5. Endoscopic view of the stent migrated to the bulb with a massive blood clot (a) and endoscopic view of the ulcerated choledochoduodenostomy ostium, identified after the removal of the stent and of the blood clot (a).", "width": 932, "height": 460, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "81df1903-6e45-43bc-9065-2bce88559711", "label": "a", "points": [[2.3, 2.7], [2.3, 456.2], [549.9, 456.2], [549.9, 2.7]], "color": "yellow"}, {"id": "34543722-2e52-4657-8bdc-a70b25304292", "label": "b", "points": [[563.2, 2.7], [563.2, 456.2], [926.8, 456.2], [926.8, 2.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Endoscopic", "start": 8, "end": 18, "id": 4}, {"text": "view", "start": 19, "end": 23, "id": 5}, {"text": "of", "start": 24, "end": 26, "id": 6}, {"text": "the", "start": 27, "end": 30, "id": 7}, {"text": "stent", "start": 31, "end": 36, "id": 8}, {"text": "migrated", "start": 37, "end": 45, "id": 9}, {"text": "to", "start": 46, "end": 48, "id": 10}, {"text": "the", "start": 49, "end": 52, "id": 11}, {"text": "bulb", "start": 53, "end": 57, "id": 12}, {"text": "with", "start": 58, "end": 62, "id": 13}, {"text": "a", "start": 63, "end": 64, "id": 14}, {"text": "massive", "start": 65, "end": 72, "id": 15}, {"text": "blood", "start": 73, "end": 78, "id": 16}, {"text": "clot", "start": 79, "end": 83, "id": 17}, {"text": "(", "start": 84, "end": 85, "id": 18}, {"text": "a", "start": 85, "end": 86, "id": 19}, {"text": ")", "start": 86, "end": 87, "id": 20}, {"text": "and", "start": 88, "end": 91, "id": 21}, {"text": "endoscopic", "start": 92, "end": 102, "id": 22}, {"text": "view", "start": 103, "end": 107, "id": 23}, {"text": "of", "start": 108, "end": 110, "id": 24}, {"text": "the", "start": 111, "end": 114, "id": 25}, {"text": "ulcerated", "start": 115, "end": 124, "id": 26}, {"text": "choledochoduodenostomy", "start": 125, "end": 147, "id": 27}, {"text": "ostium", "start": 148, "end": 154, "id": 28}, {"text": ",", "start": 154, "end": 155, "id": 29}, {"text": "identified", "start": 156, "end": 166, "id": 30}, {"text": "after", "start": 167, "end": 172, "id": 31}, {"text": "the", "start": 173, "end": 176, "id": 32}, {"text": "removal", "start": 177, "end": 184, "id": 33}, {"text": "of", "start": 185, "end": 187, "id": 34}, {"text": "the", "start": 188, "end": 191, "id": 35}, {"text": "stent", "start": 192, "end": 197, "id": 36}, {"text": "and", "start": 198, "end": 201, "id": 37}, {"text": "of", "start": 202, "end": 204, "id": 38}, {"text": "the", "start": 205, "end": 208, "id": 39}, {"text": "blood", "start": 209, "end": 214, "id": 40}, {"text": "clot", "start": 215, "end": 219, "id": 41}, {"text": "(", "start": 220, "end": 221, "id": 42}, {"text": "a", "start": 221, "end": 222, "id": 43}, {"text": ")", "start": 222, "end": 223, "id": 44}, {"text": ".", "start": 223, "end": 224, "id": 45}]}
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{"pdf_hash": "ab1cb24ac087fe41fbf4c6ce313a778eae2a817f", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Figure 5. DJANGOS emerge from atypical nuclear pores. HeLa cells over-expressing B12-HA were visualized by electron microscopy. A. A double-walled membrane body within the nucleus connects to a tube (arrow), which then intermingles with other tubes in various orientations. The cytoplasm is at the lower left. B. Double-membrane body in proximity to the nuclear envelope connects to a complex structure extending into the nucleus. Cytoplasm is at left. C. Simple double-membrane structure extending into the nucleus from an atypical nuclear pore (indicated by the arrow). Cytoplasm is at top. D. Complex double-membrane structure containing two atypical nuclear pores (indicated by the arrows) connected to tubular structures inside the nucleus. 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{"pdf_hash": "31bb22b7c627330b830db509d9ef07888bd56945", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) The left lower lip showed diffuse edema, and the left chin skin was red with hot temperature; (B) cobblestone formation was visible on the left buccal mucosa. Note that the mandibular molars developed black residual roots; (C) residual roots were present in the mandibular molars, and x-ray shadow around roots suggested apical periodontitis; (D and E) high-power magnification demonstrated granulomatous inflammation (E, arrow) beneath the cobblestone mucosa with multinucleated giant cells (D, arrow); (F and G) the swelling and redness disappeared on the lower lip and left chin, and cobblestone formation was invisible on the left buccal mucosa after treatment.", "width": 1330, "height": 438, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "c": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69], "d": [71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100], "e": [71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 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{"pdf_hash": "87dccdef123cdb58649ded5ee5701c4ef6d01de3", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Biopsy specimen of swollen left clavicular LN. Cells are poorly differentiated adenocarcinoma. (A) HE staining (original magnification, \u00d7 100). Immunostaining shows that cancerous cells have nuclear expression of Cdx2 protein (B), intense and widespread positivity for CK20 protein (C) and negative immunostaining for CK7 (D).", "width": 874, "height": 666, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 30, 31], "c": [32, 33, 34, 35, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 30, 31], "d": [33, 34, 35, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "fe43ab3e-ffde-4025-bca8-50b234862ebf", "label": "a", "points": [[25.6, 2.5], [25.6, 313.2], [442.6, 313.2], [442.6, 2.5]], "color": "yellow"}, {"id": "80758cbe-fab8-4c97-a70b-bfe478f72c14", "label": "b", "points": [[452.2, -0.2], [452.2, 317.3], [867.8, 317.3], [867.8, -0.2]], "color": "cyan"}, {"id": "7b4daa5e-c65a-458e-b159-8868fb28d5fa", "label": "c", "points": [[32.5, 318.7], [32.5, 636.3], [445.3, 636.3], [445.3, 318.7]], "color": "magenta"}, {"id": "fc70aafe-2169-4566-a30f-27f7887c1ce2", "label": "d", "points": [[452.2, 322.9], [452.2, 640.4], [870.6, 640.4], [870.6, 322.9]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Biopsy", "start": 10, "end": 16, "id": 3}, {"text": "specimen", "start": 17, "end": 25, "id": 4}, {"text": "of", "start": 26, "end": 28, "id": 5}, {"text": "swollen", "start": 29, "end": 36, "id": 6}, {"text": "left", "start": 37, "end": 41, "id": 7}, {"text": "clavicular", "start": 42, "end": 52, "id": 8}, {"text": "LN", "start": 53, "end": 55, "id": 9}, {"text": ".", "start": 55, "end": 56, "id": 10}, {"text": "Cells", "start": 57, "end": 62, "id": 11}, {"text": "are", "start": 63, "end": 66, "id": 12}, {"text": "poorly", "start": 67, "end": 73, "id": 13}, {"text": "differentiated", "start": 74, "end": 88, "id": 14}, {"text": "adenocarcinoma", "start": 89, "end": 103, "id": 15}, {"text": ".", "start": 103, "end": 104, "id": 16}, {"text": "(", "start": 105, "end": 106, "id": 17}, {"text": "A", "start": 106, "end": 107, "id": 18}, {"text": ")", "start": 107, "end": 108, "id": 19}, {"text": "HE", "start": 109, "end": 111, "id": 20}, {"text": "staining", "start": 112, "end": 120, "id": 21}, {"text": "(", "start": 121, "end": 122, "id": 22}, {"text": "original", "start": 122, "end": 130, "id": 23}, {"text": "magnification", "start": 131, "end": 144, "id": 24}, {"text": ",", "start": 144, "end": 145, "id": 25}, {"text": "\u00d7", "start": 146, "end": 147, "id": 26}, {"text": "100", "start": 148, "end": 151, "id": 27}, {"text": ")", "start": 151, "end": 152, "id": 28}, {"text": ".", "start": 152, "end": 153, "id": 29}, {"text": "Immunostaining", "start": 154, "end": 168, "id": 30}, {"text": "shows", "start": 169, "end": 174, "id": 31}, {"text": "that", "start": 175, "end": 179, "id": 32}, {"text": "cancerous", "start": 180, "end": 189, "id": 33}, {"text": "cells", "start": 190, "end": 195, "id": 34}, {"text": "have", "start": 196, "end": 200, "id": 35}, {"text": "nuclear", "start": 201, "end": 208, "id": 36}, {"text": "expression", "start": 209, "end": 219, "id": 37}, {"text": "of", "start": 220, "end": 222, "id": 38}, {"text": "Cdx2", "start": 223, "end": 227, "id": 39}, {"text": "protein", "start": 228, "end": 235, "id": 40}, {"text": "(", "start": 236, "end": 237, "id": 41}, {"text": "B", "start": 237, "end": 238, "id": 42}, {"text": ")", "start": 238, "end": 239, "id": 43}, {"text": ",", "start": 239, "end": 240, "id": 44}, {"text": "intense", "start": 241, "end": 248, "id": 45}, {"text": "and", "start": 249, "end": 252, "id": 46}, {"text": "widespread", "start": 253, "end": 263, "id": 47}, {"text": "positivity", "start": 264, "end": 274, "id": 48}, {"text": "for", "start": 275, "end": 278, "id": 49}, {"text": "CK20", "start": 279, "end": 283, "id": 50}, {"text": "protein", "start": 284, "end": 291, "id": 51}, {"text": "(", "start": 292, "end": 293, "id": 52}, {"text": "C", "start": 293, "end": 294, "id": 53}, {"text": ")", "start": 294, "end": 295, "id": 54}, {"text": "and", "start": 296, "end": 299, "id": 55}, {"text": "negative", "start": 300, "end": 308, "id": 56}, {"text": "immunostaining", "start": 309, "end": 323, "id": 57}, {"text": "for", "start": 324, "end": 327, "id": 58}, {"text": "CK7", "start": 328, "end": 331, "id": 59}, {"text": "(", "start": 332, "end": 333, "id": 60}, {"text": "D", "start": 333, "end": 334, "id": 61}, {"text": ")", "start": 334, "end": 335, "id": 62}, {"text": ".", "start": 335, "end": 336, "id": 63}]}
{"pdf_hash": "cb0d6e1c01e2825fa0042067a1a4e729d73cedc4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. These transverse histological sections of a human embryo with 10 pairs of somites (Carnegie stage 10) show the inner architecture of an S-shaped heart tube as seen in routine histological preparations. The heart was fixed in a systolic state so that its lumen is partially obliterated. (A) Section at the level of the proximal outflow (= OF) of the ventricular tube. (B) Section of at the level of the inflow (= IF) of the ventricular tube. (C) Section at the level of the developing\u2013right and left atrial appendages (= RAA, LAA). Note that the myocardium (= M) and endocardium (= E) are separated by an \u201cempty\u201d space, called the myoendocardial space. Note also: (1) The difference in the thickness of the myoendocardial space between the developing atria and ventricles; and (2) the paired character of the myoendocardial space, which reflects the origin of the heart from bilaterally paired heart fields. The dorsal mesocardium (= DM, and indicated by orange asterisks) and the obliterated endocardial tube can be used as anatomical landmarks for the original midsagittal fusion plane of the left- and right-sided heart fields (marked by the dotted line in section C). Light blue asterisks mark the original ventral midline of the heart tube. 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{"pdf_hash": "759b32f933dfc3a696fe269d77245d2ecf313b70", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Sagittal TSE T2-weighted image (July 2015) showing no abnormal findings in the L5-S1 foraminal space (a). Sagittal TSE T2-weighted image (b), axial TSE T2-weighted image (c) and sagittal fat-sat TSE T2-weighted image (d) showing a hyperintense round-shaped lesion involving the right L5-S1 foraminal space. Sagittal SE T1-weighted image (e) showing an hypointense mass in the L5-S1 foraminal space; coronal (f) and axial (g) fat-sat SE T1-weighted image after intravenous contrast administration showing avid enhancement of the lesion. 18F \u2013 FDG (18F-Fluorodeoxyglucose) CT-PET (Fig. 2h) showing focal hyperaccumulation within the sacral foramina of right S1 nerve root (SUV max. 5.2).", "width": 1004, "height": 1612, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "c": [33, 34, 35, 36, 37, 38, 39, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "d": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "e": [65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80], "f": [82, 83, 84, 85, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107], "g": [87, 88, 89, 90, 91, 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{"pdf_hash": "83ced8bd43ddc6c20ba4cd6c43e5d5271a1100a2", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Acetylcholinesterase histochemistry was used in a 91-year-old control brain to delineate Ch4 from other components of the forebrain. A\u2013D represent increasingly more caudal coronal sections and contain the anteromedial (am), anterolateral (al), anterointermediate (ai), intermediodorsal (id), intermedioventral (iv), and posterior (p) sectors of Ch4. Medial is to the left, dorsal toward the top. Section A is at approximately the same level as Figure 3. 35. ac, Anterior commissure; Am, amygdala; an, ansa lenticularis; ap, ansa peduncularis; bl, basolateral nucleus of the amygdala; GPe, GPi, GPv, external, internal, and medial sectors of the globus pallidus; hc, head of the caudate; Hp, hippocampal formation; ic, internal capsule; iml, internal medullary lamina of the globus pallidus; Nhl, nucleus of the horizontal limb; nst, nucleus of the stria terminalis; ot, optic tract; pt, putamen; son, supraoptic nucleus; st, striatal islands; tc, tail of caudate; vt, temporal horn of lateral ventricle. 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{"pdf_hash": "1fb78d794f8efbcae05436d0fd983d7729b7747f", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIGURE 2 Immunofluorescent localization of vinculin (A), talin (8), the 135-kD protein (C), and actin (D) in thin frozen sections of chicken gizzard smooth muscle. Notice the punctate labeling for vinculin and talin along the cell membranes and the apparent absence of labeling for the 135-kD protein. Actin was abundant throughout the cytoplasm of muscle cells with very little labeling of the connective tissue (ct). 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{"pdf_hash": "2681232e72e75ce3ec9aa7da3099c8c9f5ca3531", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A CT angiography slice from lower lobe in mediastinum window (A) and lung (B) window shows lobulated circumscribed mass connecting with curvilinear contrast enhancing structures suggesting pulmonary vessels.", "width": 1264, "height": 514, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [3, 4, 5, 6, 7, 8, 9, 10, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "1ec86ca1-6b07-4bfc-b393-5da518087f88", "label": "a", "points": [[6.3, 10.7], [6.3, 481.9], [631.4, 481.9], [631.4, 10.7]], "color": "yellow"}, {"id": "0a24a82a-97c4-4fda-8c50-452f4d98a930", "label": "b", "points": [[641.3, 10.7], [641.3, 491.9], [1262.4, 491.9], [1262.4, 10.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "CT", "start": 12, "end": 14, "id": 4}, {"text": "angiography", "start": 15, "end": 26, "id": 5}, {"text": "slice", "start": 27, "end": 32, "id": 6}, {"text": "from", "start": 33, "end": 37, "id": 7}, {"text": "lower", "start": 38, "end": 43, "id": 8}, {"text": "lobe", "start": 44, "end": 48, "id": 9}, {"text": "in", "start": 49, "end": 51, "id": 10}, {"text": "mediastinum", "start": 52, "end": 63, "id": 11}, {"text": "window", "start": 64, "end": 70, "id": 12}, {"text": "(", "start": 71, "end": 72, "id": 13}, {"text": "A", "start": 72, "end": 73, "id": 14}, {"text": ")", "start": 73, "end": 74, "id": 15}, {"text": "and", "start": 75, "end": 78, "id": 16}, {"text": "lung", "start": 79, "end": 83, "id": 17}, {"text": "(", "start": 84, "end": 85, "id": 18}, {"text": "B", "start": 85, "end": 86, "id": 19}, {"text": ")", "start": 86, "end": 87, "id": 20}, {"text": "window", "start": 88, "end": 94, "id": 21}, {"text": "shows", "start": 95, "end": 100, "id": 22}, {"text": "lobulated", "start": 101, "end": 110, "id": 23}, {"text": "circumscribed", "start": 111, "end": 124, "id": 24}, {"text": "mass", "start": 125, "end": 129, "id": 25}, {"text": "connecting", "start": 130, "end": 140, "id": 26}, {"text": "with", "start": 141, "end": 145, "id": 27}, {"text": "curvilinear", "start": 146, "end": 157, "id": 28}, {"text": "contrast", "start": 158, "end": 166, "id": 29}, {"text": "enhancing", "start": 167, "end": 176, "id": 30}, {"text": "structures", "start": 177, "end": 187, "id": 31}, {"text": "suggesting", "start": 188, "end": 198, "id": 32}, {"text": "pulmonary", "start": 199, "end": 208, "id": 33}, {"text": "vessels", "start": 209, "end": 216, "id": 34}, {"text": ".", "start": 216, "end": 217, "id": 35}]}
{"pdf_hash": "e1e9f87303c720e22f25803ddeb125ef3b3e8890", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. The process of measurement of total plaque volume (TPV) by manual planimetry. Three-dimensional ultrasound images of plaque volumes were acquired from the longitudinal and cross sectional carotid scans. Plaque boundaries were traced using a mouse driven cross-haired cursor and cross-sectional area of the plaque was delineated from 8-12 transverse sections of the image between the edges of the plaque, and the mean plaque volume value of 3 measurements of each plaque was used for analysis. 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{"pdf_hash": "fc78d36b3dabeee032dfeb21a425ad621c354812", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Parasagittal section through the tail of a 15-d embryo. (A) Antibodies to TGF-I~ incubated with uncoupled agarose (see Materials and Methods) stain connective tissue sheaths of muscle; (B) an equivalent aliquot of antibody incubated with agarose to which TGF-13 had been coupled gave no staining. Dilution of the anti-TGF-I~ IgG preparation was 1:390. 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{"pdf_hash": "1a166fe5d7d4a12d4ca096c14d4a80fd18269765", "fig_key": "Figure17", "fig_uri": "13-Figure17-1.png", "text": "Figure 17. Hydatid cyst. (a) Photograph of a resected hepatic hydatid cyst shows the fibrous pericyst (arrowheads) and the opened endocyst (arrow). (b) Portalvenous-phase contrast-enhanced CT scan obtained in a 45-year-old sheep raiser shows two cystic lesions in the liver with subtotally calcified walls (arrows). (c) Fast spin-echo T2-weighted MR image obtained in a 32- year-old man shows a solitary hyperintense lesion in the right lobe of the liver. 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{"pdf_hash": "5d9c72c8f227b467e7291156894dc69c51233d35", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5 LOVE - axial (panel a), \u2212 sagittal (panel b), - coronal (panel c), and 3D (panel d) reformations of a 72 year-old male patient who underwent cardiac CTA 9 months after implantation of a ACP\u00ae LAA occlusion device. Panels a, b, and c show optimal positioning of the device with no peri-device leak, complete lobe coverage as well as complete neo-endothelialization of the device suggested by the absence of contrast enhancement < 50 Hounsfield units in the LAA (* in B and C). 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{"pdf_hash": "6ac69c59617a3875536c3f0e44daab7f9d26c2e3", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Hematoxylin and eosin staining of retinal sections. (A) WT control animals reveal clearly defined nuclear and plexiform layers. (B) WT hypo mouse retinas reveal thin and highly disorganized cell and plexiform layers with numerous pyknotic cells (arrow).The ganglion cell layer appear thin and is populated by small cell bodies. The smaller picture shows a central section of a WT hypo specimen with almost no survival. (C) KO control mice display clearly defined nuclear and plexiform layers. (D) Hypoperfused Gal-3 knockout mouse retinas (KO hypo) show a clearly laminated architecture with well populated cell layers. 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{"pdf_hash": "a3ba4351342de31e045768d38954219e0ef62fdc", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Gadolinium-enhanced T1-weighted imaging. (A) Sagittal and (B, C) axial views. Partial enhancement was found in the posterior regions of the C4 (arrows) and C5 cord (arrowheads).", "width": 960, "height": 700, "subcaptions": {"a": [9, 10, 11, 12, 20, 21], "b": [14, 15, 16, 17, 18, 19, 20, 21]}, "subfigures": [{"id": "7051a8a9-5155-4fb7-8cce-01ef94042f66", "label": "a", "points": [[1.5, 0], [1.5, 665.8], [505, 665.8], [505, 0]], "color": "yellow"}, {"id": "93b41a85-21e1-462b-9ee5-942d9211f303", "label": "b", "points": [[944.8, 3], [944.8, 329.1], [517.2, 329.1], [517.2, 3]], "color": "cyan"}, {"id": "5a1cc0b1-9ae6-4b0f-b2f8-2964e721a7bd", "label": "b", "points": [[943.3, 338.2], [943.3, 670.3], [518.7, 670.3], [518.7, 338.2]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Gadolinium", "start": 10, "end": 20, "id": 3}, {"text": "-", "start": 20, "end": 21, "id": 4}, {"text": "enhanced", "start": 21, "end": 29, "id": 5}, {"text": "T1-weighted", "start": 30, "end": 41, "id": 6}, {"text": "imaging", "start": 42, "end": 49, "id": 7}, {"text": ".", "start": 49, "end": 50, "id": 8}, {"text": "(", "start": 51, "end": 52, "id": 9}, {"text": "A", "start": 52, "end": 53, "id": 10}, {"text": ")", "start": 53, "end": 54, "id": 11}, {"text": "Sagittal", "start": 55, "end": 63, "id": 12}, {"text": "and", "start": 64, "end": 67, "id": 13}, {"text": "(", "start": 68, "end": 69, "id": 14}, {"text": "B", "start": 69, "end": 70, "id": 15}, {"text": ",", "start": 70, "end": 71, "id": 16}, {"text": "C", "start": 72, "end": 73, "id": 17}, {"text": ")", "start": 73, "end": 74, "id": 18}, {"text": "axial", "start": 75, "end": 80, "id": 19}, {"text": "views", "start": 81, "end": 86, "id": 20}, {"text": ".", "start": 86, "end": 87, "id": 21}, {"text": "Partial", "start": 88, "end": 95, "id": 22}, {"text": "enhancement", "start": 96, "end": 107, "id": 23}, {"text": "was", "start": 108, "end": 111, "id": 24}, {"text": "found", "start": 112, "end": 117, "id": 25}, {"text": "in", "start": 118, "end": 120, "id": 26}, {"text": "the", "start": 121, "end": 124, "id": 27}, {"text": "posterior", "start": 125, "end": 134, "id": 28}, {"text": "regions", "start": 135, "end": 142, "id": 29}, {"text": "of", "start": 143, "end": 145, "id": 30}, {"text": "the", "start": 146, "end": 149, "id": 31}, {"text": "C4", "start": 150, "end": 152, "id": 32}, {"text": "(", "start": 153, "end": 154, "id": 33}, {"text": "arrows", "start": 154, "end": 160, "id": 34}, {"text": ")", "start": 160, "end": 161, "id": 35}, {"text": "and", "start": 162, "end": 165, "id": 36}, {"text": "C5", "start": 166, "end": 168, "id": 37}, {"text": "cord", "start": 169, "end": 173, "id": 38}, {"text": "(", "start": 174, "end": 175, "id": 39}, {"text": "arrowheads", "start": 175, "end": 185, "id": 40}, {"text": ")", "start": 185, "end": 186, "id": 41}, {"text": ".", "start": 186, "end": 187, "id": 42}]}
{"pdf_hash": "85a30596e6b162a018ca5045b980b77cec61f90c", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 Example of complete response to SBRT assessed by MRI. a The initial abdominal MRI scan with the primary HCC indicated by the arrow. b MRI scan of 6 months after SBRT. This patient was classified as CR at 6 months after SBRT. c MRI scan of 3 years after SBRT. The lesion in liver reveals changes after treatment and no activity", "width": 1014, "height": 1018, "subcaptions": {"a": [49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "140d9637-22ff-4c5a-87a7-a77d63deb65d", "label": "a", "points": [[36.8, 19.2], [36.8, 323.6], [338, 323.6], [338, 19.2]], "color": "yellow"}, {"id": "6abc8abf-76ee-4e4f-989f-97b8da320dc6", "label": "a", "points": [[352.4, 326.8], [352.4, 25.6], [653.6, 25.6], [653.6, 326.8]], "color": "cyan"}, {"id": "94a63d57-cf29-45e7-8f7b-82bc74837305", "label": "a", "points": [[672.8, 19.2], [672.8, 330], [980.4, 330], [980.4, 19.2]], "color": "magenta"}, {"id": "4e019af7-66d4-4a06-9539-511b5e0b93f3", "label": "b", "points": [[35.2, 647.2], [35.2, 352.4], [338, 352.4], [338, 647.2]], "color": "springgreen"}, {"id": "20cdd076-dbd3-4f08-8653-0a3bfa1f4112", "label": "b", "points": [[350.8, 352.4], [350.8, 658.4], [661.6, 658.4], [661.6, 352.4]], "color": "tomato"}, {"id": 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{"pdf_hash": "7ef58948e8ee077c57be59b5db9268e1de2b7995", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Expression of p21 waf1/cip1 protein in esophageal squamous cell carcinomas and normal esophageal epithelium. Acetone \u00aexed frozen tissue sections were incubated with 0.3% H 2 O 2 in methanol for 20 min to quench endogenous peroxidase activity followed by 3% BSA blocking at room temperature for 20 min. The anti p21 waf1/cip1 monoclonal antibody (187, Santa Cruz Biotechnology, CA, USA) was used as primary antibody. Sections were incubated with primary antibody for 16 h at 48C. Color was developed using Vectastain ABC Elite Kit and di-aminobenzidine as chromogen as described previously (Gaur et al., 1997). (a) H&E staining of a well dierentiated ESCC section. (b) Well dierentiated ESCC section showing intense p21 waf1/cip1 nuclear staining. (c) H&E staining of a poorly dierentiated ESCC section. (d) Poorly dierentiated ESCC section showing moderate p21 waf1/cip1 nuclear staining. (e) H&E staining of normal esophageal epithelium. 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{"pdf_hash": "ea9d2f6a1e9905c0979edb0d56d747bf45dc4732", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 T2-weighted, fat-suppressed sagittal magnetic resonance images showing a hyperintense (a) dot (arrow) and (b) line (arrowhead) at the interface between the fragment and the lesion.", "width": 652, "height": 566, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "500591d1-14d2-4240-85bc-f1c519a9e2e4", "label": "a", "points": [[2.1, 0.9], [2.1, 534.4], [294.6, 534.4], [294.6, 0.9]], "color": "yellow"}, {"id": "d75b751e-5e83-47a1-814b-b4cb37fbb80a", "label": "b", "points": [[299.8, 0.9], [299.8, 532.3], [645.8, 532.3], [645.8, 0.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "T2-weighted", "start": 9, "end": 20, "id": 2}, {"text": ",", "start": 20, "end": 21, "id": 3}, {"text": "fat", "start": 22, "end": 25, "id": 4}, {"text": "-", "start": 25, "end": 26, "id": 5}, {"text": "suppressed", "start": 26, "end": 36, "id": 6}, {"text": "sagittal", "start": 37, "end": 45, "id": 7}, {"text": "magnetic", "start": 46, "end": 54, "id": 8}, {"text": "resonance", "start": 55, "end": 64, "id": 9}, {"text": "images", "start": 65, "end": 71, "id": 10}, {"text": "showing", "start": 72, "end": 79, "id": 11}, {"text": "a", "start": 80, "end": 81, "id": 12}, {"text": "hyperintense", "start": 82, "end": 94, "id": 13}, {"text": "(", "start": 95, "end": 96, "id": 14}, {"text": "a", "start": 96, "end": 97, "id": 15}, {"text": ")", "start": 97, "end": 98, "id": 16}, {"text": "dot", "start": 99, "end": 102, "id": 17}, {"text": "(", "start": 103, "end": 104, "id": 18}, {"text": "arrow", "start": 104, "end": 109, "id": 19}, {"text": ")", "start": 109, "end": 110, "id": 20}, {"text": "and", "start": 111, "end": 114, "id": 21}, {"text": "(", "start": 115, "end": 116, "id": 22}, {"text": "b", "start": 116, "end": 117, "id": 23}, {"text": ")", "start": 117, "end": 118, "id": 24}, {"text": "line", "start": 119, "end": 123, "id": 25}, {"text": "(", "start": 124, "end": 125, "id": 26}, {"text": "arrowhead", "start": 125, "end": 134, "id": 27}, {"text": ")", "start": 134, "end": 135, "id": 28}, {"text": "at", "start": 136, "end": 138, "id": 29}, {"text": "the", "start": 139, "end": 142, "id": 30}, {"text": "interface", "start": 143, "end": 152, "id": 31}, {"text": "between", "start": 153, "end": 160, "id": 32}, {"text": "the", "start": 161, "end": 164, "id": 33}, {"text": "fragment", "start": 165, "end": 173, "id": 34}, {"text": "and", "start": 174, "end": 177, "id": 35}, {"text": "the", "start": 178, "end": 181, "id": 36}, {"text": "lesion", "start": 182, "end": 188, "id": 37}, {"text": ".", "start": 188, "end": 189, "id": 38}]}
{"pdf_hash": "64ae039bbbd4262e50af9de7612804128bf202c1", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Radiological and histopathological findings. a A chest radiograph showing a mass in the right upper lung field. b A chest computed tomography scan showing a mass with an irregular surface in the right upper lobe. c Gross examination showing a solid tumor (diameter, 5 cm) with internal bleeding. d-g Topographic presentation of the cut surface shows three different components; portion A: well-differentiated adenocarcinoma (e), portion B: poorly differentiated adenocarcinoma (f), and portion C: sarcomatoid cancer (g). The ratio of the area occupied by these 3 components, i.e. well-differentiated adenocarcinoma: poorly differentiated adenocarcinoma: sarcomatoid cancer, is 15: 80: 5. 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{"pdf_hash": "6a32e65cfc4a10e7838e75cc4f1e1a5403016dc0", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Immunofiuorescent staining of doubly infected BHK-21 cells. The cells were treated with antibody 11/4 (specific for Flo HA) followed by a rhodamine-conjugated goat anti-mouse antibody. After washing, the preparation was incubated with biotinylated antibody N1 (specific for Meg HA) followed by fluoresceinconjugated streptavidin. (Left) Rhodamine-stained cells demonstrating the presence of Flo HA at the plasma membrane. (Right) The corresponding fluorescein staining with the anti-Meg HA antibody. >95% of the cells expressed both HA types. 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{"pdf_hash": "8d214179b574df248a90ec9b06875fb73f9bdc98", "fig_key": "Figure3", "fig_uri": "20-Figure3-1.png", "text": "Figure 3. FUS-mediated gadolinium delivery in the rat brain is dependent on ultrasound pressure (A) MRgFUS-mediated BBB disruption, measured by gadolinium delivery, is enhanced at 0.6 MPa compared to 0.4 MPa, shown by high resolution T1-weighted MR images. Left column, pre-sonication coronal images. Middle column, post-sonication contrast enhanced coronal images. Right column, post-sonication contrast enhanced sagittal images. 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{"pdf_hash": "ebfe35bb99953a13ca7a5772ea2b7180878058f1", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Figure 3. Example of graft-versus-tumor response in a patient with mantle-cell lymphoma treated with allogeneic hematopoietic cell transplantation (HCT) after non-myeloablative conditioning with fludarabine and low-dose (2 Gy) total body irradiation (TBI). At the time of allogeneic HCT the patient had recurrent disease following treatment with high-dose radiolabeled antibodies and autologous peripheral-blood stem-cell support. (A) Pretransplantation computed tomography (CT) scan image (day e27) through the upper pelvis demonstrating a mass 8 cm \u00c2 7 cm extending through 12 0.5-cm cuts. (B) CT scan image through the same region demonstrating complete resolution of the mass on day \u00fe74 after non-myeloablative transplantation from an HLA-matched unrelated donor. The patient has remained in remission 30 months after transplantation with no evidence of graft-versus-host disease (GVHD). 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{"pdf_hash": "1883f3935343168b77c98bbd5e81506f499eddb6", "fig_key": "Figure12", "fig_uri": "13-Figure12-1.png", "text": "Figure 12 A 63-year-old female under evaluation for ovarian mass. (A) Sagittal T2W images showing a well-defined complex ovarian cyst showing hyperintense solid component which shows post contrast enhancement (black arrowhead-B) and restricted diffusion (black arrow-C) with low ADC values (white arrow-D). Restricted diffusion in the solid component was suggestive of this lesion to be a malignant ovarian mass. 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{"pdf_hash": "ab5085fe1c96134071aa95c584dfcbc62ed14690", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 Case 14 presented with a visual acuity of 40 letters at baseline according to the ETDRS chart. The patient was treated with 5 consecutive intravitreal ranibizumab injections. At the 12-month follow-up, the visual acuity of the patient had improved to 63 letters according to ETDRS. a Fundus photography at baseline. b Baseline fluorescein angiography and indocyanine green angiography showing complex vascular and polypoidal lesions. c Optical coherence tomography at baseline. d Fundus photography at the 12-month follow-up. e Fluorescein angiography and indocyanine green angiography showing complete polyp regression at the 12month follow-up. f Optical coherence tomography at the 12- month follow-up showing the resolution of PED and the return of the normal foveal depression", "width": 1014, "height": 890, "subcaptions": {"a": [54, 55, 56, 57, 58, 59], "b": [60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74], "d": [82, 83, 84, 85, 86, 87, 88, 89, 90, 91], "e": [92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109], "f": [110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 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{"pdf_hash": "6ca9bb25e81a9564abfe62775afb8d3ff35bd1b7", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Tumor response during sorafenib treatment. PET/CT showed multiple lesions in both lungs (a1), mediastinal lymph nodes (a2) and abdominal cavity (a3). No lesion was found in the liver by PET/CT (a3), abdominal MRI (d1-d3). 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{"pdf_hash": "9fbf47e149a689be57048da83ecbcf6f4ca2020b", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "Fig. 7 (A) Transverse section of an actually structuring osteon forming a tunnel of about 250 mm; it contains a central arteriole and two capillaries with a thin endothelial wall. Osteoblasts are present in the lower zone of the canal surface (between arrows), but no complete concentric lamellar system is yet evident. Haematoxylin-eosin stain (bar = 50 \u03bcm). (B) Longitudinal section of the cortex showing an actually structuring osteon with osteoclasts at the head of the cutting cone diverging to form a bifurcation. Haematoxylin-eosin stain (bar = 50 \u03bcm). (C) Vessel turning in a circle and closing a loop at short distance from a bifurcation (arrow). 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{"pdf_hash": "9116b9a0fc66537e030f55c2e1587a2ff3efe1c0", "fig_key": "Figure3", "fig_uri": "10-Figure3-1.png", "text": "FIGURE 3. Septic embolism. Lung infarction by a septic thrombus from the tricuspid valve in a 21-yr-old female with endocarditis. Repeated blood cultures and culture of the valve disclosed a positive culture for Staphylococcus aureus. a) A haematoxylin- and eosin-stained section of this infarcted lung specimen shows the obstructed large pulmonary artery branch and surrounding lung tissue with coagulation necrosis (original magnification 640). b) Chest computed tomography of this patient with endocarditis of the tricuspidal valve and pulmonary septic emboli. Axial computed tomography showing multiple irregular nodules of which some are cavitated. 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{"pdf_hash": "5fbf0084605114eaea3a120975c8cf9e371aa78b", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Fig. 2 Nasoseptal flap necrosis. Left: Intraoperative endoscopic view of a necrotic NSF (circle). Right: Normal NSF with CSF leak (arrow). (Adapted from Chabot et al, 2018 5 ). CSF, cerebrospinal fluid; NSF, nasoseptal flap.", "width": 984, "height": 426, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "1bc400b6-a216-4acb-9f49-fe2694db12bc", "label": "a", "points": [[28, 1.6], [28, 393.3], [478.8, 393.3], [478.8, 1.6]], "color": "yellow"}, {"id": "8d915eb7-b3a5-4395-a0d3-692b44423325", "label": "b", "points": [[491.2, 391.8], [491.2, 3.1], [956.1, 3.1], [956.1, 391.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Nasoseptal", "start": 7, "end": 17, "id": 3}, {"text": "flap", "start": 18, "end": 22, "id": 4}, {"text": "necrosis", "start": 23, "end": 31, "id": 5}, {"text": ".", "start": 31, "end": 32, "id": 6}, {"text": "Left", "start": 33, "end": 37, "id": 7}, {"text": ":", "start": 37, "end": 38, "id": 8}, {"text": "Intraoperative", "start": 39, "end": 53, "id": 9}, {"text": "endoscopic", "start": 54, "end": 64, "id": 10}, {"text": "view", "start": 65, "end": 69, "id": 11}, {"text": "of", "start": 70, "end": 72, "id": 12}, {"text": "a", "start": 73, "end": 74, "id": 13}, {"text": "necrotic", "start": 75, "end": 83, "id": 14}, {"text": "NSF", "start": 84, "end": 87, "id": 15}, {"text": "(", "start": 88, "end": 89, "id": 16}, {"text": "circle", "start": 89, "end": 95, "id": 17}, {"text": ")", "start": 95, "end": 96, "id": 18}, {"text": ".", "start": 96, "end": 97, "id": 19}, {"text": "Right", "start": 98, "end": 103, "id": 20}, {"text": ":", "start": 103, "end": 104, "id": 21}, {"text": "Normal", "start": 105, "end": 111, "id": 22}, {"text": "NSF", "start": 112, "end": 115, "id": 23}, {"text": "with", "start": 116, "end": 120, "id": 24}, {"text": "CSF", "start": 121, "end": 124, "id": 25}, {"text": "leak", "start": 125, "end": 129, "id": 26}, {"text": "(", "start": 130, "end": 131, "id": 27}, {"text": "arrow", "start": 131, "end": 136, "id": 28}, {"text": ")", "start": 136, "end": 137, "id": 29}, {"text": ".", "start": 137, "end": 138, "id": 30}, {"text": "(", "start": 139, "end": 140, "id": 31}, {"text": "Adapted", "start": 140, "end": 147, "id": 32}, {"text": "from", "start": 148, "end": 152, "id": 33}, {"text": "Chabot", "start": 153, "end": 159, "id": 34}, {"text": "et", "start": 160, "end": 162, "id": 35}, {"text": "al", "start": 163, "end": 165, "id": 36}, {"text": ",", "start": 165, "end": 166, "id": 37}, {"text": "2018", "start": 167, "end": 171, "id": 38}, {"text": "5", "start": 172, "end": 173, "id": 39}, {"text": ")", "start": 174, "end": 175, "id": 40}, {"text": ".", "start": 175, "end": 176, "id": 41}, {"text": "CSF", "start": 177, "end": 180, "id": 42}, {"text": ",", "start": 180, "end": 181, "id": 43}, {"text": "cerebrospinal", "start": 182, "end": 195, "id": 44}, {"text": "fluid", "start": 196, "end": 201, "id": 45}, {"text": ";", "start": 201, "end": 202, "id": 46}, {"text": "NSF", "start": 203, "end": 206, "id": 47}, {"text": ",", "start": 206, "end": 207, "id": 48}, {"text": "nasoseptal", "start": 208, "end": 218, "id": 49}, {"text": "flap", "start": 219, "end": 223, "id": 50}, {"text": ".", "start": 223, "end": 224, "id": 51}]}
{"pdf_hash": "805a90cc9192883f7322892dbc0f8902c67bd336", "fig_key": "Figure9", "fig_uri": "10-Figure9-1.png", "text": "Fig. 9 a Coronal scan shows obliteration of the external auditory canal with broad changes and osteolysis of the temporal bone. b Coronal scan post-op. shows involvement of the middle ear and stapes", "width": 652, "height": 770, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "89e1a06a-7790-4077-96ae-201e9154ee37", "label": "a", "points": [[31.9, 24.7], [31.9, 388.3], [627.3, 388.3], [627.3, 24.7]], "color": "yellow"}, {"id": "d7807c4a-2f14-47f1-8222-882ea5c935c9", "label": "b", "points": [[26.8, 738.5], [26.8, 391.4], [623.2, 391.4], [623.2, 738.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "9", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Coronal", "start": 9, "end": 16, "id": 4}, {"text": "scan", "start": 17, "end": 21, "id": 5}, {"text": "shows", "start": 22, "end": 27, "id": 6}, {"text": "obliteration", "start": 28, "end": 40, "id": 7}, {"text": "of", "start": 41, "end": 43, "id": 8}, {"text": "the", "start": 44, "end": 47, "id": 9}, {"text": "external", "start": 48, "end": 56, "id": 10}, {"text": "auditory", "start": 57, "end": 65, "id": 11}, {"text": "canal", "start": 66, "end": 71, "id": 12}, {"text": "with", "start": 72, "end": 76, "id": 13}, {"text": "broad", "start": 77, "end": 82, "id": 14}, {"text": "changes", "start": 83, "end": 90, "id": 15}, {"text": "and", "start": 91, "end": 94, "id": 16}, {"text": "osteolysis", "start": 95, "end": 105, "id": 17}, {"text": "of", "start": 106, "end": 108, "id": 18}, {"text": "the", "start": 109, "end": 112, "id": 19}, {"text": "temporal", "start": 113, "end": 121, "id": 20}, {"text": "bone", "start": 122, "end": 126, "id": 21}, {"text": ".", "start": 126, "end": 127, "id": 22}, {"text": "b", "start": 128, "end": 129, "id": 23}, {"text": "Coronal", "start": 130, "end": 137, "id": 24}, {"text": "scan", "start": 138, "end": 142, "id": 25}, {"text": "post", "start": 143, "end": 147, "id": 26}, {"text": "-", "start": 147, "end": 148, "id": 27}, {"text": "op", "start": 148, "end": 150, "id": 28}, {"text": ".", "start": 150, "end": 151, "id": 29}, {"text": "shows", "start": 152, "end": 157, "id": 30}, {"text": "involvement", "start": 158, "end": 169, "id": 31}, {"text": "of", "start": 170, "end": 172, "id": 32}, {"text": "the", "start": 173, "end": 176, "id": 33}, {"text": "middle", "start": 177, "end": 183, "id": 34}, {"text": "ear", "start": 184, "end": 187, "id": 35}, {"text": "and", "start": 188, "end": 191, "id": 36}, {"text": "stapes", "start": 192, "end": 198, "id": 37}]}
{"pdf_hash": "774c68596406600ca6ccff8020abace72883aeb6", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Pleomorphic adenoma (hematoxylin-eosin). A, Typical pleomorphic adenoma with a myxoid stroma and cellular myoepithelial area. Focal squamous metaplasia is present (arrows) (original magnification \u03eb100). B, Atypical pleomorphic adenoma with focal nuclear enlargement and prominent nucleoli within epithelial cells lining glands (original magnification \u03eb200). C, Atypical pleomorphic adenoma with moderate nuclear enlargement and pleomorphism and prominent nucleoli (original magnification \u03eb200). D, Focus of marked nuclear pleomorphism within a pleomorphic adenoma. In this tumor, myoepithelial cells, some with plasmacytoid or hyaline morphology, are the cells with pleomorphic nucleoli. 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{"pdf_hash": "89737f2e5ba9461212d221d9f027242d9cd9d771", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: Axial (a), sagittal (b) and coronal (c) contrast-enhanced T1-weighted MRI scans demonstrate the fourth ventricle lesion with intense enhancement c b a", "width": 1070, "height": 400, "subcaptions": {"a": [3, 4, 5, 6, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [8, 9, 10, 11, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "c": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "d0ab4749-ce77-4caa-aa12-f3ae6a826b6d", "label": "a", "points": [[28.7, 0], [28.7, 373.6], [333, 373.6], [333, 0]], "color": "yellow"}, {"id": "ff90a855-2800-4d82-9b4c-ded1a7d74caf", "label": "b", "points": [[346.5, 377], [346.5, 3.4], [667.7, 3.4], [667.7, 377]], "color": "cyan"}, {"id": "7c41cdcb-c9b3-49ea-8700-d0225bb4c427", "label": "c", "points": [[671.1, 3.4], [671.1, 377], [1036.2, 377], [1036.2, 3.4]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Axial", "start": 10, "end": 15, "id": 3}, {"text": "(", "start": 16, "end": 17, "id": 4}, {"text": "a", "start": 17, "end": 18, "id": 5}, {"text": ")", "start": 18, "end": 19, "id": 6}, {"text": ",", "start": 19, "end": 20, "id": 7}, {"text": "sagittal", "start": 21, "end": 29, "id": 8}, {"text": "(", "start": 30, "end": 31, "id": 9}, {"text": "b", "start": 31, "end": 32, "id": 10}, {"text": ")", "start": 32, "end": 33, "id": 11}, {"text": "and", "start": 34, "end": 37, "id": 12}, {"text": "coronal", "start": 38, "end": 45, "id": 13}, {"text": "(", "start": 46, "end": 47, "id": 14}, {"text": "c", "start": 47, "end": 48, "id": 15}, {"text": ")", "start": 48, "end": 49, "id": 16}, {"text": "contrast", "start": 50, "end": 58, "id": 17}, {"text": "-", "start": 58, "end": 59, "id": 18}, {"text": "enhanced", "start": 59, "end": 67, "id": 19}, {"text": "T1-weighted", "start": 68, "end": 79, "id": 20}, {"text": "MRI", "start": 80, "end": 83, "id": 21}, {"text": "scans", "start": 84, "end": 89, "id": 22}, {"text": "demonstrate", "start": 90, "end": 101, "id": 23}, {"text": "the", "start": 102, "end": 105, "id": 24}, {"text": "fourth", "start": 106, "end": 112, "id": 25}, {"text": "ventricle", "start": 113, "end": 122, "id": 26}, {"text": "lesion", "start": 123, "end": 129, "id": 27}, {"text": "with", "start": 130, "end": 134, "id": 28}, {"text": "intense", "start": 135, "end": 142, "id": 29}, {"text": "enhancement", "start": 143, "end": 154, "id": 30}, {"text": "c", "start": 155, "end": 156, "id": 31}, {"text": "b", "start": 157, "end": 158, "id": 32}, {"text": "a", "start": 159, "end": 160, "id": 33}]}
{"pdf_hash": "715824f25ba70050b767671ef10f7be3c0cc4d9e", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. (CT scan): (A and B) The multiloculated cystic retroperitoneal lesion (white arrows), at the level of the second portion of the duodenum in continuity with the pancreatic head which is displaced anteriorly and to the right.", "width": 622, "height": 712, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "1e493e86-9397-4d88-8933-6daba3f82278", "label": "a", "points": [[2.5, 0], [2.5, 349], [619.5, 349], [619.5, 0]], "color": "yellow"}, {"id": "ff3a86ac-d09c-45a0-a4c2-3f9f0a6e25ca", "label": "b", "points": [[0.5, 363], [0.5, 709], [621.5, 709], [621.5, 363]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "CT", "start": 11, "end": 13, "id": 4}, {"text": "scan", "start": 14, "end": 18, "id": 5}, {"text": ")", "start": 18, "end": 19, "id": 6}, {"text": ":", "start": 19, "end": 20, "id": 7}, {"text": "(", "start": 21, "end": 22, "id": 8}, {"text": "A", "start": 22, "end": 23, "id": 9}, {"text": "and", "start": 24, "end": 27, "id": 10}, {"text": "B", "start": 28, "end": 29, "id": 11}, {"text": ")", "start": 29, "end": 30, "id": 12}, {"text": "The", "start": 31, "end": 34, "id": 13}, {"text": "multiloculated", "start": 35, "end": 49, "id": 14}, {"text": "cystic", "start": 50, "end": 56, "id": 15}, {"text": "retroperitoneal", "start": 57, "end": 72, "id": 16}, {"text": "lesion", "start": 73, "end": 79, "id": 17}, {"text": "(", "start": 80, "end": 81, "id": 18}, {"text": "white", "start": 81, "end": 86, "id": 19}, {"text": "arrows", "start": 87, "end": 93, "id": 20}, {"text": ")", "start": 93, "end": 94, "id": 21}, {"text": ",", "start": 94, "end": 95, "id": 22}, {"text": "at", "start": 96, "end": 98, "id": 23}, {"text": "the", "start": 99, "end": 102, "id": 24}, {"text": "level", "start": 103, "end": 108, "id": 25}, {"text": "of", "start": 109, "end": 111, "id": 26}, {"text": "the", "start": 112, "end": 115, "id": 27}, {"text": "second", "start": 116, "end": 122, "id": 28}, {"text": "portion", "start": 123, "end": 130, "id": 29}, {"text": "of", "start": 131, "end": 133, "id": 30}, {"text": "the", "start": 134, "end": 137, "id": 31}, {"text": "duodenum", "start": 138, "end": 146, "id": 32}, {"text": "in", "start": 147, "end": 149, "id": 33}, {"text": "continuity", "start": 150, "end": 160, "id": 34}, {"text": "with", "start": 161, "end": 165, "id": 35}, {"text": "the", "start": 166, "end": 169, "id": 36}, {"text": "pancreatic", "start": 170, "end": 180, "id": 37}, {"text": "head", "start": 181, "end": 185, "id": 38}, {"text": "which", "start": 186, "end": 191, "id": 39}, {"text": "is", "start": 192, "end": 194, "id": 40}, {"text": "displaced", "start": 195, "end": 204, "id": 41}, {"text": "anteriorly", "start": 205, "end": 215, "id": 42}, {"text": "and", "start": 216, "end": 219, "id": 43}, {"text": "to", "start": 220, "end": 222, "id": 44}, {"text": "the", "start": 223, "end": 226, "id": 45}, {"text": "right", "start": 227, "end": 232, "id": 46}, {"text": ".", "start": 232, "end": 233, "id": 47}]}
{"pdf_hash": "491f9bad338dc751bafb3392d289325281056a8e", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A chest radiography revealed elevation of the diaphragm due to dilated and gaseous intestines (a). A radiograph of the abdomen revealed diffusely dilated intestines and multiple, small radiolucent linear bubbles lining the intestines (circle) (b). Abdominal computed tomography revealed dilated and gaseous small intestines, retention of gas in the intestinal wall (circle) (c), and intraperitoneal free air (arrows) (d). 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{"pdf_hash": "fdec31e6e6a136dbbcf2568f04b7c80ff064f52e", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. (a) Postoperative computed tomography (CT)-scan showing the good shape of the reconstructed aortic root and arch. (b) Three-dimensional CT-scan demonstrating optimal fitting of the stent-graft.", "width": 566, "height": 1022, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "3ce953f7-b9f5-4c7a-ad01-a3ff1d45bafb", "label": "a", "points": [[38.5, 0], [38.5, 486], [541.5, 486], [541.5, 0]], "color": "yellow"}, {"id": "4a655442-2823-4729-8b42-fa75732eaca9", "label": "b", "points": [[540.5, 503], [540.5, 1002], [35.5, 1002], [35.5, 503]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "a", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Postoperative", "start": 12, "end": 25, "id": 7}, {"text": "computed", "start": 26, "end": 34, "id": 8}, {"text": "tomography", "start": 35, "end": 45, "id": 9}, {"text": "(", "start": 46, "end": 47, "id": 10}, {"text": "CT)-scan", "start": 47, "end": 55, "id": 11}, {"text": "showing", "start": 56, "end": 63, "id": 12}, {"text": "the", "start": 64, "end": 67, "id": 13}, {"text": "good", "start": 68, "end": 72, "id": 14}, {"text": "shape", "start": 73, "end": 78, "id": 15}, {"text": "of", "start": 79, "end": 81, "id": 16}, {"text": "the", "start": 82, "end": 85, "id": 17}, {"text": "reconstructed", "start": 86, "end": 99, "id": 18}, {"text": "aortic", "start": 100, "end": 106, "id": 19}, {"text": "root", "start": 107, "end": 111, "id": 20}, {"text": "and", "start": 112, "end": 115, "id": 21}, {"text": "arch", "start": 116, "end": 120, "id": 22}, {"text": ".", "start": 120, "end": 121, "id": 23}, {"text": "(", "start": 122, "end": 123, "id": 24}, {"text": "b", "start": 123, "end": 124, "id": 25}, {"text": ")", "start": 124, "end": 125, "id": 26}, {"text": "Three", "start": 126, "end": 131, "id": 27}, {"text": "-", "start": 131, "end": 132, "id": 28}, {"text": "dimensional", "start": 132, "end": 143, "id": 29}, {"text": "CT", "start": 144, "end": 146, "id": 30}, {"text": "-", "start": 146, "end": 147, "id": 31}, {"text": "scan", "start": 147, "end": 151, "id": 32}, {"text": "demonstrating", "start": 152, "end": 165, "id": 33}, {"text": "optimal", "start": 166, "end": 173, "id": 34}, {"text": "fitting", "start": 174, "end": 181, "id": 35}, {"text": "of", "start": 182, "end": 184, "id": 36}, {"text": "the", "start": 185, "end": 188, "id": 37}, {"text": "stent", "start": 189, "end": 194, "id": 38}, {"text": "-", "start": 194, "end": 195, "id": 39}, {"text": "graft", "start": 195, "end": 200, "id": 40}, {"text": ".", "start": 200, "end": 201, "id": 41}]}
{"pdf_hash": "162ff4dd2d939a462c0abaa1c69b158a017a4a85", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Genetic Screen for Transfer of an Intron-Containing Plastid Gene to the Nuclear Genome (A) Isolation of putative gene transfer lines. Growth on kanamycin-containing medium suggests activation of the formerly silent nptII gene, presumably through functional transfer to the nuclear genome. Two typical selection plates (with one positive line each) were photographed after 18 days (left) and 40 days (right). Note that the sensitive seedlings are still slightly green after 18 days (which, at least in part, is due to the high sowing density) but nearly fully bleached after 40 days. Scale bars represent 20 mm. (B) Mendelian segregation of the activated kanamycin resistance gene confirms gene transfer to the nucleus. Shown are examples of inheritance assays performed by sowing seeds on kanamycin-containing medium (kanamycin concentration: 200 mg/L). The seeds from the cGTas-Kan lines used in these tests were generated by using the cGTas-Kan lines as pollen donors and crossing them to a WT maternal parent. Both putative gene transfer lines show the expected 1:1 segregation into kanamycin-resistant and kanamycin-sensitive progeny. The total segregation ratio determined was resistant: sensitive = 214: 203 for line cGTas-Kan1 (51.3% resistant seedlings) and resistant: sensitive = 279: 211 for line cGTas-Kan2 (56.9% resistant seedlings). 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{"pdf_hash": "9ce8eb72eef3178e4ea279e0c52d406956357a34", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Magnetic resonance imaging (MRI) from case one shows increased periventricular T2 signal on axial FLAIR sequences (a) with ependymal enhancement lining the ventricle (b). MRI from case two shows hydrocephalus with subtle ependymal enhancement lining the ventricles (c).", "width": 602, "height": 1622, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [32, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 24, 25, 26, 27, 28, 29, 30, 31], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "8257989d-b62d-47a0-8d0c-d198e960ee2c", "label": "a", "points": [[24.5, 4], [24.5, 562], [568.5, 562], [568.5, 4]], "color": "yellow"}, {"id": "be1dd539-8a91-4994-ad00-33f5e91e5b6f", "label": "b", "points": [[24.5, 565], [24.5, 947], [566.5, 947], [566.5, 565]], "color": "cyan"}, {"id": "c3397b88-8936-4bb1-886a-0712a13d0b9f", "label": "c", "points": [[25.5, 951], [25.5, 1589], [568.5, 1589], [568.5, 951]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Magnetic", "start": 9, "end": 17, "id": 2}, {"text": "resonance", "start": 18, "end": 27, "id": 3}, {"text": "imaging", "start": 28, "end": 35, "id": 4}, {"text": "(", "start": 36, "end": 37, "id": 5}, {"text": "MRI", "start": 37, "end": 40, "id": 6}, {"text": ")", "start": 40, "end": 41, "id": 7}, {"text": "from", "start": 42, "end": 46, "id": 8}, {"text": "case", "start": 47, "end": 51, "id": 9}, {"text": "one", "start": 52, "end": 55, "id": 10}, {"text": "shows", "start": 56, "end": 61, "id": 11}, {"text": "increased", "start": 62, "end": 71, "id": 12}, {"text": "periventricular", "start": 72, "end": 87, "id": 13}, {"text": "T2", "start": 88, "end": 90, "id": 14}, {"text": "signal", "start": 91, "end": 97, "id": 15}, {"text": "on", "start": 98, "end": 100, "id": 16}, {"text": "axial", "start": 101, "end": 106, "id": 17}, {"text": "FLAIR", "start": 107, "end": 112, "id": 18}, {"text": "sequences", "start": 113, "end": 122, "id": 19}, {"text": "(", "start": 123, "end": 124, "id": 20}, {"text": "a", "start": 124, "end": 125, "id": 21}, {"text": ")", "start": 125, "end": 126, "id": 22}, {"text": "with", "start": 127, "end": 131, "id": 23}, {"text": "ependymal", "start": 132, "end": 141, "id": 24}, {"text": "enhancement", "start": 142, "end": 153, "id": 25}, {"text": "lining", "start": 154, "end": 160, "id": 26}, {"text": "the", "start": 161, "end": 164, "id": 27}, {"text": "ventricle", "start": 165, "end": 174, "id": 28}, {"text": "(", "start": 175, "end": 176, "id": 29}, {"text": "b", "start": 176, "end": 177, "id": 30}, {"text": ")", "start": 177, "end": 178, "id": 31}, {"text": ".", "start": 178, "end": 179, "id": 32}, {"text": "MRI", "start": 180, "end": 183, "id": 33}, {"text": "from", "start": 184, "end": 188, "id": 34}, {"text": "case", "start": 189, "end": 193, "id": 35}, {"text": "two", "start": 194, "end": 197, "id": 36}, {"text": "shows", "start": 198, "end": 203, "id": 37}, {"text": "hydrocephalus", "start": 204, "end": 217, "id": 38}, {"text": "with", "start": 218, "end": 222, "id": 39}, {"text": "subtle", "start": 223, "end": 229, "id": 40}, {"text": "ependymal", "start": 230, "end": 239, "id": 41}, {"text": "enhancement", "start": 240, "end": 251, "id": 42}, {"text": "lining", "start": 252, "end": 258, "id": 43}, {"text": "the", "start": 259, "end": 262, "id": 44}, {"text": "ventricles", "start": 263, "end": 273, "id": 45}, {"text": "(", "start": 274, "end": 275, "id": 46}, {"text": "c", "start": 275, "end": 276, "id": 47}, {"text": ")", "start": 276, "end": 277, "id": 48}, {"text": ".", "start": 277, "end": 278, "id": 49}]}
{"pdf_hash": "a107e4febb16f5ac97e362df15bc16557e11797e", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig. 5 Contrast-enhanced 3-D CT images of a cervical spine injury with luxation of C3/4. Both CR (a) and VR (b) images show the anterior subluxation of the cervical vertebrae (arrows). The enhanced lightning of CR creates a high contrast between vessels and bone, making it easy to follow the course of the vertebral artery", "width": 894, "height": 528, "subcaptions": {"a": [19, 20, 21, 22, 23, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 19, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "bc483949-2ae0-4fc0-bf85-626443ba0402", "label": "b", "points": [[28.5, 52.7], [28.5, 527.3], [453.6, 527.3], [453.6, 52.7]], "color": "yellow"}, {"id": "2003b73e-bae0-4bf9-9e25-034a35d9541a", "label": "b", "points": [[467.7, 51.3], [467.7, 523.1], [887.2, 523.1], [887.2, 51.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": "Contrast", "start": 7, "end": 15, "id": 3}, {"text": "-", "start": 15, "end": 16, "id": 4}, {"text": "enhanced", "start": 16, "end": 24, "id": 5}, {"text": "3-D", "start": 25, "end": 28, "id": 6}, {"text": "CT", "start": 29, "end": 31, "id": 7}, {"text": "images", "start": 32, "end": 38, "id": 8}, {"text": "of", "start": 39, "end": 41, "id": 9}, {"text": "a", "start": 42, "end": 43, "id": 10}, {"text": "cervical", "start": 44, "end": 52, "id": 11}, {"text": "spine", "start": 53, "end": 58, "id": 12}, {"text": "injury", "start": 59, "end": 65, "id": 13}, {"text": "with", "start": 66, "end": 70, "id": 14}, {"text": "luxation", "start": 71, "end": 79, "id": 15}, {"text": "of", "start": 80, "end": 82, "id": 16}, {"text": "C3/4", "start": 83, "end": 87, "id": 17}, {"text": ".", "start": 87, "end": 88, "id": 18}, {"text": "Both", "start": 89, "end": 93, "id": 19}, {"text": "CR", "start": 94, "end": 96, "id": 20}, {"text": "(", "start": 97, "end": 98, "id": 21}, {"text": "a", "start": 98, "end": 99, "id": 22}, {"text": ")", "start": 99, "end": 100, "id": 23}, {"text": "and", "start": 101, "end": 104, "id": 24}, {"text": "VR", "start": 105, "end": 107, "id": 25}, {"text": "(", "start": 108, "end": 109, "id": 26}, {"text": "b", "start": 109, "end": 110, "id": 27}, {"text": ")", "start": 110, "end": 111, "id": 28}, {"text": "images", "start": 112, "end": 118, "id": 29}, {"text": "show", "start": 119, "end": 123, "id": 30}, {"text": "the", "start": 124, "end": 127, "id": 31}, {"text": "anterior", "start": 128, "end": 136, "id": 32}, {"text": "subluxation", "start": 137, "end": 148, "id": 33}, {"text": "of", "start": 149, "end": 151, "id": 34}, {"text": "the", "start": 152, "end": 155, "id": 35}, {"text": "cervical", "start": 156, "end": 164, "id": 36}, {"text": "vertebrae", "start": 165, "end": 174, "id": 37}, {"text": "(", "start": 175, "end": 176, "id": 38}, {"text": "arrows", "start": 176, "end": 182, "id": 39}, {"text": ")", "start": 182, "end": 183, "id": 40}, {"text": ".", "start": 183, "end": 184, "id": 41}, {"text": "The", "start": 185, "end": 188, "id": 42}, {"text": "enhanced", "start": 189, "end": 197, "id": 43}, {"text": "lightning", "start": 198, "end": 207, "id": 44}, {"text": "of", "start": 208, "end": 210, "id": 45}, {"text": "CR", "start": 211, "end": 213, "id": 46}, {"text": "creates", "start": 214, "end": 221, "id": 47}, {"text": "a", "start": 222, "end": 223, "id": 48}, {"text": "high", "start": 224, "end": 228, "id": 49}, {"text": "contrast", "start": 229, "end": 237, "id": 50}, {"text": "between", "start": 238, "end": 245, "id": 51}, {"text": "vessels", "start": 246, "end": 253, "id": 52}, {"text": "and", "start": 254, "end": 257, "id": 53}, {"text": "bone", "start": 258, "end": 262, "id": 54}, {"text": ",", "start": 262, "end": 263, "id": 55}, {"text": "making", "start": 264, "end": 270, "id": 56}, {"text": "it", "start": 271, "end": 273, "id": 57}, {"text": "easy", "start": 274, "end": 278, "id": 58}, {"text": "to", "start": 279, "end": 281, "id": 59}, {"text": "follow", "start": 282, "end": 288, "id": 60}, {"text": "the", "start": 289, "end": 292, "id": 61}, {"text": "course", "start": 293, "end": 299, "id": 62}, {"text": "of", "start": 300, "end": 302, "id": 63}, {"text": "the", "start": 303, "end": 306, "id": 64}, {"text": "vertebral", "start": 307, "end": 316, "id": 65}, {"text": "artery", "start": 317, "end": 323, "id": 66}]}
{"pdf_hash": "b3bddd5ca2f95c6c0830bcdbfc816074c40712b4", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: Computed tomography (CT) myelography images from a 73-year-old man (body weight 56 kg) with severe lumbar canal stenosis at the level of L1-L2 and multiple compression fractures (T10, T12, and L1). (a) Sagittal conventional CT myelography image. (b) Sagittal virtual monochromatic image (55 keV). (c) Sagittal virtual monochromatic image (40 keV). (d) Axial conventional CT myelography image at T6. (e) Axial virtual monochromatic image (55 keV). 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{"pdf_hash": "c623fc7ee67d555cabac501a0310b06dab01b86a", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. A 64-year-old man in whom ICC recurred 9 months after partial resection of right hepatic lobe. A: MRI showed an irregular tumor located at the edge of resection on the T2-weighted image. B: Intercostal sonograms showed a 4.2 cm tumor and it was treated by sonography-guided RFA. C: On 1-month CT, the margin of the ablation zone was obscure and coarse, without sufficient safety margin. D: A repeated RFA was performed for the unablated tumor area. E: CT scan 3 months after repeated RFA showed that ablated zone had clear margin and no enhancement. 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{"pdf_hash": "1e5d24e535c4ed3a3f958e191af8cd2ea439a539", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 (A) Preoperative lateral radiograph revealing an L1 severe osteoporotic compression fracture with marked kyphosis. (B) Postoperative lateral radiograph revealing the presence of cement within the vertebral body, and demonstrating slight regaining of anterior vertebral body height. (C) Axial CT scan at L1 revealing the radiopaque cement filling the vertebral body.", "width": 1332, "height": 568, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "c": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "4bc2afe7-ed14-42d7-85f7-f47941cdc175", "label": "a", "points": [[1.1, 1.4], [1.1, 542.2], [373.5, 542.2], [373.5, 1.4]], "color": "yellow"}, {"id": "a11d96d2-5d1e-41f4-8eb0-ed4b7c3dff15", "label": "b", "points": [[384, 1.4], [384, 544.3], [754.4, 544.3], [754.4, 1.4]], "color": "cyan"}, {"id": "d235dc42-9e86-4186-959b-b9db4237517d", "label": "c", "points": [[767, 540.1], [767, 3.5], [1326.8, 3.5], [1326.8, 540.1]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "(", "start": 7, "end": 8, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": ")", "start": 9, "end": 10, "id": 5}, {"text": "Preoperative", "start": 11, "end": 23, "id": 6}, {"text": "lateral", "start": 24, "end": 31, "id": 7}, {"text": "radiograph", "start": 32, "end": 42, "id": 8}, {"text": "revealing", "start": 43, "end": 52, "id": 9}, {"text": "an", "start": 53, "end": 55, "id": 10}, {"text": "L1", "start": 56, "end": 58, "id": 11}, {"text": "severe", "start": 59, "end": 65, "id": 12}, {"text": "osteoporotic", "start": 66, "end": 78, "id": 13}, {"text": "compression", "start": 79, "end": 90, "id": 14}, {"text": "fracture", "start": 91, "end": 99, "id": 15}, {"text": "with", "start": 100, "end": 104, "id": 16}, {"text": "marked", "start": 105, "end": 111, "id": 17}, {"text": "kyphosis", "start": 112, "end": 120, "id": 18}, {"text": ".", "start": 120, "end": 121, "id": 19}, {"text": "(", "start": 122, "end": 123, "id": 20}, {"text": "B", "start": 123, "end": 124, "id": 21}, {"text": ")", "start": 124, "end": 125, "id": 22}, {"text": "Postoperative", "start": 126, "end": 139, "id": 23}, {"text": "lateral", "start": 140, "end": 147, "id": 24}, {"text": "radiograph", "start": 148, "end": 158, "id": 25}, {"text": "revealing", "start": 159, "end": 168, "id": 26}, {"text": "the", "start": 169, "end": 172, "id": 27}, {"text": "presence", "start": 173, "end": 181, "id": 28}, {"text": "of", "start": 182, "end": 184, "id": 29}, {"text": "cement", "start": 185, "end": 191, "id": 30}, {"text": "within", "start": 192, "end": 198, "id": 31}, {"text": "the", "start": 199, "end": 202, "id": 32}, {"text": "vertebral", "start": 203, "end": 212, "id": 33}, {"text": "body", "start": 213, "end": 217, "id": 34}, {"text": ",", "start": 217, "end": 218, "id": 35}, {"text": "and", "start": 219, "end": 222, "id": 36}, {"text": "demonstrating", "start": 223, "end": 236, "id": 37}, {"text": "slight", "start": 237, "end": 243, "id": 38}, {"text": "regaining", "start": 244, "end": 253, "id": 39}, {"text": "of", "start": 254, "end": 256, "id": 40}, {"text": "anterior", "start": 257, "end": 265, "id": 41}, {"text": "vertebral", "start": 266, "end": 275, "id": 42}, {"text": "body", "start": 276, "end": 280, "id": 43}, {"text": "height", "start": 281, "end": 287, "id": 44}, {"text": ".", "start": 287, "end": 288, "id": 45}, {"text": "(", "start": 289, "end": 290, "id": 46}, {"text": "C", "start": 290, "end": 291, "id": 47}, {"text": ")", "start": 291, "end": 292, "id": 48}, {"text": "Axial", "start": 293, "end": 298, "id": 49}, {"text": "CT", "start": 299, "end": 301, "id": 50}, {"text": "scan", "start": 302, "end": 306, "id": 51}, {"text": "at", "start": 307, "end": 309, "id": 52}, {"text": "L1", "start": 310, "end": 312, "id": 53}, {"text": "revealing", "start": 313, "end": 322, "id": 54}, {"text": "the", "start": 323, "end": 326, "id": 55}, {"text": "radiopaque", "start": 327, "end": 337, "id": 56}, {"text": "cement", "start": 338, "end": 344, "id": 57}, {"text": "filling", "start": 345, "end": 352, "id": 58}, {"text": "the", "start": 353, "end": 356, "id": 59}, {"text": "vertebral", "start": 357, "end": 366, "id": 60}, {"text": "body", "start": 367, "end": 371, "id": 61}, {"text": ".", "start": 371, "end": 372, "id": 62}]}
{"pdf_hash": "c707a67740068adb5e87626384ae45c8ebda32c3", "fig_key": "Figure12", "fig_uri": "11-Figure12-1.png", "text": "Figure 12. Ultra structure of wild type and ms21 sperm axonemes. A, Schematic of an axial fiber of Drosophila sperm, adapted from Nielsen and Raff [72] showing the typical 9+9+2 arrangement of microtubules (see text for details). B, Wild type post-individualization axonemes, each wrapped in its own membrane showing the typical 9+9+2 architecture. Each axial fiber in a sperm is associated with two mitochondrial derivatives, a major (M) and a minor (m) one (long and short arrows in B, respectively). C, ms21 axonemes from unindividualized sperm bundle showing various defects: in the axoneme on the left, both the mitochondrial derivatives are of the same size while in the axoneme towards right, m is larger than M, and the two are not properly orientated, unlike in wild type, where M is always larger than m and they are oriented in a particular angle with respect to the axial fiber. The radial spokes and the secondary fibers (sf, long white arrow) in both the axonemes of ms21 are not uniformly organized. Some of the secondary fibers in the axoneme towards right are enlarged and appear as tubules. Outer and inner dynein arms associated with some of the peripheral doublets in both axonemes are normal (short white arrows) but are reduced in some doublets (black arrows). Since none of the sperm bundle completes individualization in the ms21 testes, distinct cell membranes between different axonemes were not identifiable. 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{"pdf_hash": "c186b9ad028d07c40b859e4afa53fe9d9a1cfe81", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Fig. 2. A 39-year-old female patient with ruptured right IC-ophthalmic aneurysm. (A) Brain CT scan revealed a diffuse IVH, and a large ICH in the left prefrontal area with an estimated volume of 56 mL. (B) Brain CTA and DSA revealed a 12 mm ruptured right-IC-Ophthalmic aneurysm. (C-E) She underwent endovascular coil embolization using 7 coils (C: preoperative, D: postoperative), which was followed by SRH and EVD (E: postoperative). (F) Seven days later, a brain CT scan revealed a significant decrease in ICH and IVH. 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{"pdf_hash": "dce2de8b87dd3421fe299e067e9eed8faab7529a", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. p16INK4a staining in a case of allograft nephropathy. (A) Zero biopsy from a 19-year-old donor with no p16INK4a staining. (B) Oneyear follow-up biopsy diagnosed with allograft nephropathy showing nuclear and cytoplasmic staining for p16INK4a in tubular cells. The amount of nuclear staining is compatible with what was found in normal kidneys from individuals in their eighties.", "width": 618, "height": 922, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "bc493707-349f-4126-8aab-b631b258905d", "label": "a", "points": [[3, 1.8], [3, 439.8], [615, 439.8], [615, 1.8]], "color": "yellow"}, {"id": "31071ce2-8905-4e78-a546-327db2206415", "label": "b", "points": [[5, 460.3], [5, 899.4], [614, 899.4], [614, 460.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "p16INK4a", "start": 8, "end": 16, "id": 4}, {"text": "staining", "start": 17, "end": 25, "id": 5}, {"text": "in", "start": 26, "end": 28, "id": 6}, {"text": "a", "start": 29, "end": 30, "id": 7}, {"text": "case", "start": 31, "end": 35, "id": 8}, {"text": "of", "start": 36, "end": 38, "id": 9}, {"text": "allograft", "start": 39, "end": 48, "id": 10}, {"text": "nephropathy", "start": 49, "end": 60, "id": 11}, {"text": ".", "start": 60, "end": 61, "id": 12}, {"text": "(", "start": 62, "end": 63, "id": 13}, {"text": "A", "start": 63, "end": 64, "id": 14}, {"text": ")", "start": 64, "end": 65, "id": 15}, {"text": "Zero", "start": 66, "end": 70, "id": 16}, {"text": "biopsy", "start": 71, "end": 77, "id": 17}, {"text": "from", "start": 78, "end": 82, "id": 18}, {"text": "a", "start": 83, "end": 84, "id": 19}, {"text": "19-year", "start": 85, "end": 92, "id": 20}, {"text": "-", "start": 92, "end": 93, "id": 21}, {"text": "old", "start": 93, "end": 96, "id": 22}, {"text": "donor", "start": 97, "end": 102, "id": 23}, {"text": "with", "start": 103, "end": 107, "id": 24}, {"text": "no", "start": 108, "end": 110, "id": 25}, {"text": "p16INK4a", "start": 111, "end": 119, "id": 26}, {"text": "staining", "start": 120, "end": 128, "id": 27}, {"text": ".", "start": 128, "end": 129, "id": 28}, {"text": "(", "start": 130, "end": 131, "id": 29}, {"text": "B", "start": 131, "end": 132, "id": 30}, {"text": ")", "start": 132, "end": 133, "id": 31}, {"text": "Oneyear", "start": 134, "end": 141, "id": 32}, {"text": "follow", "start": 142, "end": 148, "id": 33}, {"text": "-", "start": 148, "end": 149, "id": 34}, {"text": "up", "start": 149, "end": 151, "id": 35}, {"text": "biopsy", "start": 152, "end": 158, "id": 36}, {"text": "diagnosed", "start": 159, "end": 168, "id": 37}, {"text": "with", "start": 169, "end": 173, "id": 38}, {"text": "allograft", "start": 174, "end": 183, "id": 39}, {"text": "nephropathy", "start": 184, "end": 195, "id": 40}, {"text": "showing", "start": 196, "end": 203, "id": 41}, {"text": "nuclear", "start": 204, "end": 211, "id": 42}, {"text": "and", "start": 212, "end": 215, "id": 43}, {"text": "cytoplasmic", "start": 216, "end": 227, "id": 44}, {"text": "staining", "start": 228, "end": 236, "id": 45}, {"text": "for", "start": 237, "end": 240, "id": 46}, {"text": "p16INK4a", "start": 241, "end": 249, "id": 47}, {"text": "in", "start": 250, "end": 252, "id": 48}, {"text": "tubular", "start": 253, "end": 260, "id": 49}, {"text": "cells", "start": 261, "end": 266, "id": 50}, {"text": ".", "start": 266, "end": 267, "id": 51}, {"text": "The", "start": 268, "end": 271, "id": 52}, {"text": "amount", "start": 272, "end": 278, "id": 53}, {"text": "of", "start": 279, "end": 281, "id": 54}, {"text": "nuclear", "start": 282, "end": 289, "id": 55}, {"text": "staining", "start": 290, "end": 298, "id": 56}, {"text": "is", "start": 299, "end": 301, "id": 57}, {"text": "compatible", "start": 302, "end": 312, "id": 58}, {"text": "with", "start": 313, "end": 317, "id": 59}, {"text": "what", "start": 318, "end": 322, "id": 60}, {"text": "was", "start": 323, "end": 326, "id": 61}, {"text": "found", "start": 327, "end": 332, "id": 62}, {"text": "in", "start": 333, "end": 335, "id": 63}, {"text": "normal", "start": 336, "end": 342, "id": 64}, {"text": "kidneys", "start": 343, "end": 350, "id": 65}, {"text": "from", "start": 351, "end": 355, "id": 66}, {"text": "individuals", "start": 356, "end": 367, "id": 67}, {"text": "in", "start": 368, "end": 370, "id": 68}, {"text": "their", "start": 371, "end": 376, "id": 69}, {"text": "eighties", "start": 377, "end": 385, "id": 70}, {"text": ".", "start": 385, "end": 386, "id": 71}]}
{"pdf_hash": "9a682a0516ee0f74c451232cf8d22d7e660c5484", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1. In sonographic imaging, (A) there is an irregular shaped hypoechoic nodule with internal calcifications at the mid pole (white arrow) and (B) multiple enlarged lymph nodes, ranging from 0.5 to 1 cm along the jugular chain of the neck. In microscopic view of needle biopsy, a few bacilli are noted (inset: Ziehl Neelsen, \u00d71,000).", "width": 976, "height": 392, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71]}, "subfigures": [{"id": "0d373b01-3d52-43a0-91ab-499c4685eb5c", "label": "a", "points": [[1.2, -0.3], [1.2, 363.6], [477.6, 363.6], [477.6, -0.3]], "color": "yellow"}, {"id": "c3289e73-aa97-4b3b-92be-976f799070b9", "label": "b", "points": [[491.5, 2.8], [491.5, 359], [969.5, 359], [969.5, 2.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "In", "start": 10, "end": 12, "id": 3}, {"text": "sonographic", "start": 13, "end": 24, "id": 4}, {"text": "imaging", "start": 25, "end": 32, "id": 5}, {"text": ",", "start": 32, "end": 33, "id": 6}, {"text": "(", "start": 34, "end": 35, "id": 7}, {"text": "A", "start": 35, "end": 36, "id": 8}, {"text": ")", "start": 36, "end": 37, "id": 9}, {"text": "there", "start": 38, "end": 43, "id": 10}, {"text": "is", "start": 44, "end": 46, "id": 11}, {"text": "an", "start": 47, "end": 49, "id": 12}, {"text": "irregular", "start": 50, "end": 59, "id": 13}, {"text": "shaped", "start": 60, "end": 66, "id": 14}, {"text": "hypoechoic", "start": 67, "end": 77, "id": 15}, {"text": "nodule", "start": 78, "end": 84, "id": 16}, {"text": "with", "start": 85, "end": 89, "id": 17}, {"text": "internal", "start": 90, "end": 98, "id": 18}, {"text": "calcifications", "start": 99, "end": 113, "id": 19}, {"text": "at", "start": 114, "end": 116, "id": 20}, {"text": "the", "start": 117, "end": 120, "id": 21}, {"text": "mid", "start": 121, "end": 124, "id": 22}, {"text": "pole", "start": 125, "end": 129, "id": 23}, {"text": "(", "start": 130, "end": 131, "id": 24}, {"text": "white", "start": 131, "end": 136, "id": 25}, {"text": "arrow", "start": 137, "end": 142, "id": 26}, {"text": ")", "start": 142, "end": 143, "id": 27}, {"text": "and", "start": 144, "end": 147, "id": 28}, {"text": "(", "start": 148, "end": 149, "id": 29}, {"text": "B", "start": 149, "end": 150, "id": 30}, {"text": ")", "start": 150, "end": 151, "id": 31}, {"text": "multiple", "start": 152, "end": 160, "id": 32}, {"text": "enlarged", "start": 161, "end": 169, "id": 33}, {"text": "lymph", "start": 170, "end": 175, "id": 34}, {"text": "nodes", "start": 176, "end": 181, "id": 35}, {"text": ",", "start": 181, "end": 182, "id": 36}, {"text": "ranging", "start": 183, "end": 190, "id": 37}, {"text": "from", "start": 191, "end": 195, "id": 38}, {"text": "0.5", "start": 196, "end": 199, "id": 39}, {"text": "to", "start": 200, "end": 202, "id": 40}, {"text": "1", "start": 203, "end": 204, "id": 41}, {"text": "cm", "start": 205, "end": 207, "id": 42}, {"text": "along", "start": 208, "end": 213, "id": 43}, {"text": "the", "start": 214, "end": 217, "id": 44}, {"text": "jugular", "start": 218, "end": 225, "id": 45}, {"text": "chain", "start": 226, "end": 231, "id": 46}, {"text": "of", "start": 232, "end": 234, "id": 47}, {"text": "the", "start": 235, "end": 238, "id": 48}, {"text": "neck", "start": 239, "end": 243, "id": 49}, {"text": ".", "start": 243, "end": 244, "id": 50}, {"text": "In", "start": 245, "end": 247, "id": 51}, {"text": "microscopic", "start": 248, "end": 259, "id": 52}, {"text": "view", "start": 260, "end": 264, "id": 53}, {"text": "of", "start": 265, "end": 267, "id": 54}, {"text": "needle", "start": 268, "end": 274, "id": 55}, {"text": "biopsy", "start": 275, "end": 281, "id": 56}, {"text": ",", "start": 281, "end": 282, "id": 57}, {"text": "a", "start": 283, "end": 284, "id": 58}, {"text": "few", "start": 285, "end": 288, "id": 59}, {"text": "bacilli", "start": 289, "end": 296, "id": 60}, {"text": "are", "start": 297, "end": 300, "id": 61}, {"text": "noted", "start": 301, "end": 306, "id": 62}, {"text": "(", "start": 307, "end": 308, "id": 63}, {"text": "inset", "start": 308, "end": 313, "id": 64}, {"text": ":", "start": 313, "end": 314, "id": 65}, {"text": "Ziehl", "start": 315, "end": 320, "id": 66}, {"text": "Neelsen", "start": 321, "end": 328, "id": 67}, {"text": ",", "start": 328, "end": 329, "id": 68}, {"text": "\u00d71,000", "start": 330, "end": 336, "id": 69}, {"text": ")", "start": 336, "end": 337, "id": 70}, {"text": ".", "start": 337, "end": 338, "id": 71}]}
{"pdf_hash": "e079120de79e779a7498720b82b1c5e6b5d970f5", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIG. 2.-The effect of spermidine on the incorporation of H3-uridine and on the nuclear structure of salivary gland nuclei of D. melanogaster. (A) Nucleus from salivary gland preincubated in Medium 199 containing no additions, followed by incubation in the same medium containing H3-uridine (30 Mc/ml). 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{"pdf_hash": "5c0f662c961d965936d509ff44c51f56f92aca21", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Phenobarbital addition induced a widespread abnormal EEG slowing associated with diffuse triphasic sharp waves and left temporal-parietal paroxysms (A). One week later, phenobarbital withdrawal and lacosamide addition induced a prompt recovery of vigilance level, and EEG (B) showed rare interictal sharp waves in temporal-parietal-occipital regions and normal background activity. 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{"pdf_hash": "5c33a19b29c10b39293dabc227451348431be1df", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 \u2013 Volumetric model obtained from the original multislice computed tomography (MSCT) data. The left coronary artery is marked in red. The modeled segment of plaque free coronary artery bifurcation is marked with (a).", "width": 598, "height": 584, "subcaptions": {"a": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "a0d5bc4f-376f-43a2-b2aa-1aa90b40714c", "label": "a", "points": [[292, 125.8], [292, 235.8], [449, 235.8], [449, 125.8]], "color": "yellow"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "Volumetric", "start": 9, "end": 19, "id": 4}, {"text": "model", "start": 20, "end": 25, "id": 5}, {"text": "obtained", "start": 26, "end": 34, "id": 6}, {"text": "from", "start": 35, "end": 39, "id": 7}, {"text": "the", "start": 40, "end": 43, "id": 8}, {"text": "original", "start": 44, "end": 52, "id": 9}, {"text": "multislice", "start": 53, "end": 63, "id": 10}, {"text": "computed", "start": 64, "end": 72, "id": 11}, {"text": "tomography", "start": 73, "end": 83, "id": 12}, {"text": "(", "start": 84, "end": 85, "id": 13}, {"text": "MSCT", "start": 85, "end": 89, "id": 14}, {"text": ")", "start": 89, "end": 90, "id": 15}, {"text": "data", "start": 91, "end": 95, "id": 16}, {"text": ".", "start": 95, "end": 96, "id": 17}, {"text": "The", "start": 97, "end": 100, "id": 18}, {"text": "left", "start": 101, "end": 105, "id": 19}, {"text": "coronary", "start": 106, "end": 114, "id": 20}, {"text": "artery", "start": 115, "end": 121, "id": 21}, {"text": "is", "start": 122, "end": 124, "id": 22}, {"text": "marked", "start": 125, "end": 131, "id": 23}, {"text": "in", "start": 132, "end": 134, "id": 24}, {"text": "red", "start": 135, "end": 138, "id": 25}, {"text": ".", "start": 138, "end": 139, "id": 26}, {"text": "The", "start": 140, "end": 143, "id": 27}, {"text": "modeled", "start": 144, "end": 151, "id": 28}, {"text": "segment", "start": 152, "end": 159, "id": 29}, {"text": "of", "start": 160, "end": 162, "id": 30}, {"text": "plaque", "start": 163, "end": 169, "id": 31}, {"text": "free", "start": 170, "end": 174, "id": 32}, {"text": "coronary", "start": 175, "end": 183, "id": 33}, {"text": "artery", "start": 184, "end": 190, "id": 34}, {"text": "bifurcation", "start": 191, "end": 202, "id": 35}, {"text": "is", "start": 203, "end": 205, "id": 36}, {"text": "marked", "start": 206, "end": 212, "id": 37}, {"text": "with", "start": 213, "end": 217, "id": 38}, {"text": "(", "start": 218, "end": 219, "id": 39}, {"text": "a", "start": 219, "end": 220, "id": 40}, {"text": ")", "start": 220, "end": 221, "id": 41}, {"text": ".", "start": 221, "end": 222, "id": 42}]}
{"pdf_hash": "bb3a16e245c4ed94c9b687e5001443802e2e2a39", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Computed tomography (CT) revealed two huge tumors, tumor thrombi extended from the renal tumor and deep venous thrombosis in the right iliofemoral vein. (A) The white arrowheads indicate the tumor originating from the right kidney. (B) The black arrowheads show the tumor in the ascending colon. (C) Coronal view of CT demonstrated the tumor (white arrowheads) protruding from the right kidney and the renal vein cranially compressed by the tumor. The black arrows indicate the extensive tumor thrombus in the right renal vein. (D) Coronal view of CT demonstrated the two huge tumors. The white arrowheads indicate the renal tumor, and the black arrowheads show the colon carcinoma. The two tumors compressed the inferior vena cava (IVC) to the left side. 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{"pdf_hash": "3950772880657844119969bc8260530eb10f3a64", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. A) Ultrasound imaging of intramuscular lipoma showing hyperechoic (compared to adjacent muscle), relatively well-defined mass with fine internal echoes. Reproduced under the Creative Commons Attribution License from Chernev I, 2013. 71 B) Ultrasound imaging showing heterogeneous thenar intramuscular lipoma with irregular margins and interdigitations within skeletal muscle that create the typical striated appearance. Reproduced with permission of the American Institute of Ultrasound in Medicine (Zamora MA, 2005; Permission conveyed through Copyright Clearance Center, Inc). 92 C) MRI of intramuscular lipoma of the thenar eminence. Note the fat signal intensity and homogeneous appearance of the mass. Reproduced under the Creative Commons Attribution License from Chernev I, 2013. 71 D) MRI intramuscular lipoma of the tibialis anterior muscle. Note the heterogeneous appearance of the mass with streaky intralesional structures. Reproduced with permission (Nishida J, 2007; pending permission from Springer Science and Business Media). 17 E) MRI showing a mass with increased signal intensity infiltrating the thenar muscles. The lesion appears isointense relative to subcutaneous fat and is compatible with a deep infiltrating intramuscular lipoma. Reproduced with permission of the American Institute of Ultrasound in Medicine (Zamora MA, 2005; Permission conveyed through Copyright Clearance Center, Inc). 92 F) MRI of intramuscular lipoma of the thenar eminence. Note the bilobular appearance of the tumor. 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{"pdf_hash": "30400ffbbf287b5fa5f521e97f2c4a4145f0b377", "fig_key": "Figure9", "fig_uri": "6-Figure9-1.png", "text": "Fig 9. Short condyles in coronal (A), sagittal (B), and axial (C) images.", "width": 744, "height": 258, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 21, 22], "b": [3, 4, 5, 11, 12, 13, 14, 21, 22], "c": [3, 4, 5, 17, 18, 19, 20, 21, 22]}, "subfigures": [{"id": "2e479407-3a68-4e12-a1a7-b71a671faede", "label": "a", "points": [[6.1, 2.7], [6.1, 200.2], [245.9, 200.2], [245.9, 2.7]], "color": "yellow"}, {"id": "7d654aed-daf3-4f83-8313-345c2fe28218", "label": "b", "points": [[254.1, 0.4], [254.1, 200.2], [490.3, 200.2], [490.3, 0.4]], "color": "cyan"}, {"id": "0cc3e09f-3123-4e60-adec-d824c1de8daf", "label": "c", "points": [[498.6, 1.6], [498.6, 194.3], [741.9, 194.3], [741.9, 1.6]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "9", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Short", "start": 7, "end": 12, "id": 3}, {"text": "condyles", "start": 13, "end": 21, "id": 4}, {"text": "in", "start": 22, "end": 24, "id": 5}, {"text": "coronal", "start": 25, "end": 32, "id": 6}, {"text": "(", "start": 33, "end": 34, "id": 7}, {"text": "A", "start": 34, "end": 35, "id": 8}, {"text": ")", "start": 35, "end": 36, "id": 9}, {"text": ",", "start": 36, "end": 37, "id": 10}, {"text": "sagittal", "start": 38, "end": 46, "id": 11}, {"text": "(", "start": 47, "end": 48, "id": 12}, {"text": "B", "start": 48, "end": 49, "id": 13}, {"text": ")", "start": 49, "end": 50, "id": 14}, {"text": ",", "start": 50, "end": 51, "id": 15}, {"text": "and", "start": 52, "end": 55, "id": 16}, {"text": "axial", "start": 56, "end": 61, "id": 17}, {"text": "(", "start": 62, "end": 63, "id": 18}, {"text": "C", "start": 63, "end": 64, "id": 19}, {"text": ")", "start": 64, "end": 65, "id": 20}, {"text": "images", "start": 66, "end": 72, "id": 21}, {"text": ".", "start": 72, "end": 73, "id": 22}]}
{"pdf_hash": "81958ad1d888722b92588187d8ffaf76aa74a870", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (a) Oblique coronal reformatted contrast-enhanced computed tomography of the neck in the soft tissue window showing acute thrombosis of the left brachiocephalic vein (arrowheads) extending below into the brachiocephalic vein. (b) Extension of Figure 1a indicating the location of the thrombosis and lymphadenopathy", "width": 674, "height": 388, "subcaptions": {"b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "472938d8-c8a3-4702-84ad-02665f80d950", "label": "b", "points": [[2.7, 1.1], [2.7, 351.4], [311.5, 351.4], [311.5, 1.1]], "color": "yellow"}, {"id": "6c24f2f1-bc83-4428-9777-ce750134b847", "label": "b", "points": [[320, 1.1], [320, 351.4], [668.2, 351.4], [668.2, 1.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Oblique", "start": 14, "end": 21, "id": 6}, {"text": "coronal", "start": 22, "end": 29, "id": 7}, {"text": "reformatted", "start": 30, "end": 41, "id": 8}, {"text": "contrast", "start": 42, "end": 50, "id": 9}, {"text": "-", "start": 50, "end": 51, "id": 10}, {"text": "enhanced", "start": 51, "end": 59, "id": 11}, {"text": "computed", "start": 60, "end": 68, "id": 12}, {"text": "tomography", "start": 69, "end": 79, "id": 13}, {"text": "of", "start": 80, "end": 82, "id": 14}, {"text": "the", "start": 83, "end": 86, "id": 15}, {"text": "neck", "start": 87, "end": 91, "id": 16}, {"text": "in", "start": 92, "end": 94, "id": 17}, {"text": "the", "start": 95, "end": 98, "id": 18}, {"text": "soft", "start": 99, "end": 103, "id": 19}, {"text": "tissue", "start": 104, "end": 110, "id": 20}, {"text": "window", "start": 111, "end": 117, "id": 21}, {"text": "showing", "start": 118, "end": 125, "id": 22}, {"text": "acute", "start": 126, "end": 131, "id": 23}, {"text": "thrombosis", "start": 132, "end": 142, "id": 24}, {"text": "of", "start": 143, "end": 145, "id": 25}, {"text": "the", "start": 146, "end": 149, "id": 26}, {"text": "left", "start": 150, "end": 154, "id": 27}, {"text": "brachiocephalic", "start": 155, "end": 170, "id": 28}, {"text": "vein", "start": 171, "end": 175, "id": 29}, {"text": "(", "start": 176, "end": 177, "id": 30}, {"text": "arrowheads", "start": 177, "end": 187, "id": 31}, {"text": ")", "start": 187, "end": 188, "id": 32}, {"text": "extending", "start": 189, "end": 198, "id": 33}, {"text": "below", "start": 199, "end": 204, "id": 34}, {"text": "into", "start": 205, "end": 209, "id": 35}, {"text": "the", "start": 210, "end": 213, "id": 36}, {"text": "brachiocephalic", "start": 214, "end": 229, "id": 37}, {"text": "vein", "start": 230, "end": 234, "id": 38}, {"text": ".", "start": 234, "end": 235, "id": 39}, {"text": "(", "start": 236, "end": 237, "id": 40}, {"text": "b", "start": 237, "end": 238, "id": 41}, {"text": ")", "start": 238, "end": 239, "id": 42}, {"text": "Extension", "start": 240, "end": 249, "id": 43}, {"text": "of", "start": 250, "end": 252, "id": 44}, {"text": "Figure", "start": 253, "end": 259, "id": 45}, {"text": "1a", "start": 260, "end": 262, "id": 46}, {"text": "indicating", "start": 263, "end": 273, "id": 47}, {"text": "the", "start": 274, "end": 277, "id": 48}, {"text": "location", "start": 278, "end": 286, "id": 49}, {"text": "of", "start": 287, "end": 289, "id": 50}, {"text": "the", "start": 290, "end": 293, "id": 51}, {"text": "thrombosis", "start": 294, "end": 304, "id": 52}, {"text": "and", "start": 305, "end": 308, "id": 53}, {"text": "lymphadenopathy", "start": 309, "end": 324, "id": 54}]}
{"pdf_hash": "9abc45284da97842cb018a0578f9dd233f6c6dab", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5 E1B-55K nuclear export is a ected by overexpression of retroviral shuttle proteins but not vice versa. Overexpression of HIV-1 Rev (5 mg of plasmid-DNA) a ected the nuclear export of E1B-GFP (1 mg of plasmid-DNA) (a,b). In contrast, the shuttling of Rex-GFP (1 mg of plasmid-DNA) was not inhibited by overexpression of E1B-55K (5 mg of plasmid-DNA). Asterisks are indicating cells coexpressing E1B-GFP and Rev, whereas the arrow marks a cell expressing E1B-GFP only. 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{"pdf_hash": "671e4f8b3445a26eacb6b35ea97725db8c132057", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3: Fused axial positron emission tomography/computed tomography of the neck (a) and noncontrast computed tomography (b) of the neck showing normal appearing thyroid gland with physiological uptake. Fused axial positron emission tomography/computed tomography of the chest (c) and noncontrast computed tomography (d) of the chest showing a mildly active heterogeneous anterior mediastinal mass with calcifications abutting the posterior aspect of the left brachiocephalic vein and aortic arch. This was confirmed as ectopic thyroid on biopsy d c", "width": 600, "height": 522, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [32, 33, 34, 35, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90], "d": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90]}, "subfigures": [{"id": "1df29709-847e-4857-95d3-5625f340b881", "label": "a", "points": [[35.5, 0], [35.5, 239], [300.5, 239], [300.5, 0]], "color": "yellow"}, {"id": "250590c4-3322-49e2-b646-fb9a3813117e", "label": "b", "points": [[305.5, 2], [305.5, 240], [567.5, 240], [567.5, 2]], "color": "cyan"}, {"id": "4864bd03-af13-454a-9f46-d2d0702210bb", "label": "c", 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{"pdf_hash": "31ddf500dae4cdaeabcc8455b731c4a8e972dbf4", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Invading PT phenotypes in the feronia mutant. (A-C,H,J) Cleared whole-mount preparations. (D,E,I) Ovules stained with Aniline Blue to visualize the PT. (F,G) Crosses to PT marker line expressing the \u03b2-glucuronidase (GUS) gene. (A) Mature FGs of wild-type and feronia (fer/+) plants before fertilization are indistinguishable from each other and contain synergid cells (sc), egg cell (ec) and central cell (cc). (B) Fertilized wild-type ovules at 24 HAP that contain an elongated zygote (arrow) and free nuclear endosperm (arrowheads). (C) Unfertilized feronia (fer/+) ovule at 24 HAP. The secondary endosperm nucleus (sen) of the central cell and the egg cell nucleus (ecn) are visible. The pollen tube (arrow) enters the ovule but forms an entangled structure (arrowhead) within the FG. (D) Wild-type ovule after fertilization. The PT (arrow) terminated in the micropylar area (mi) of the embryo sac. (E) feronia mutant in which the PT invades the micropylar area (arrow). (F) In wild-type ovules the GUS-activity of the PT remains restricted to the micropylar area of the FG (arrow). (G) In mutant FG the GUS signal is observed in the entire micropylar part of the FG. Owing to the strong GUS activity, the stain diffused into the central cell. (H,I) The PT enters the central cell (arrowheads) after coiling in the micropylar area (arrow). (J) Formation of free nuclear endosperm (arrowheads) after the PT has invaded the FG (arrow). 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{"pdf_hash": "f65cf733ac265b40717e8d45beca2b36b745b1d8", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Fig. 2. Axial T2-weighted image. (A) No evidence of abnormality in patient no. 9. (B) Bilateral focal hyperintensities in the thalamus (white arrows) in patient no. 19. (C) Bilateral focal hyperintensities in the putamen (black arrows) in patient no. 17. (D) Bilateral focal hyperintensities in the putamen (black arrows) and thalamus (white arrows) in patient no. 21. (E-1) Bilateral focal hyperintensities in the putamen (black arrows) and thalamus (white arrows) in patient no. 1. 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{"pdf_hash": "42b3bfd48cbfb12cd6c2f3117855046d6ad922da", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 -The posterodorsal medial amygdala (MePD) in BALB/c mice. In these Nissl-stained coronal sections taken approximately in the middle of the rostrocaudal extent of the MePD, the wedge-shaped MePD (limits indicated by arrows) abuts the ventrolateral margin of the cell-body sparse optic tract (ot; running from lower left corner of photograph to upper right) and is more slender in female (upper) than male mice (lower), resulting in sexual dimorphism in overall volume of the nucleus. IM = intercalated mass; BMA = basal medial nucleus of the amygdala; MePV = posteroventral medial amygdala. 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{"pdf_hash": "1ab8d7a3a0115e3cd9d36960e727f48d01c12667", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 A contrast-enhanced CT scan showing multiple hypo dense lesions in both kidneys (white arrows), bulkiness of both ovaries (black arrows), and permeative osteolytic lesions in the bony pelvis (arrowhead)", "width": 1040, "height": 654, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [32, 33, 34, 3, 4, 5, 6, 7, 8, 9, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "5866e56b-139e-4d97-b005-8dc33a13dd94", "label": "a", "points": [[5.8, 1.4], [5.8, 651.9], [510.2, 651.9], [510.2, 1.4]], "color": "yellow"}, {"id": "2ca5deae-2fb6-46b2-b300-8ab37dd06275", "label": "b", "points": [[521.7, 3], [521.7, 643.7], [1032.6, 643.7], [1032.6, 3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "contrast", "start": 9, "end": 17, "id": 4}, {"text": "-", "start": 17, "end": 18, "id": 5}, {"text": "enhanced", "start": 18, "end": 26, "id": 6}, {"text": "CT", "start": 27, "end": 29, "id": 7}, {"text": "scan", "start": 30, "end": 34, "id": 8}, {"text": "showing", "start": 35, "end": 42, "id": 9}, {"text": "multiple", "start": 43, "end": 51, "id": 10}, {"text": "hypo", "start": 52, "end": 56, "id": 11}, {"text": "dense", "start": 57, "end": 62, "id": 12}, {"text": "lesions", "start": 63, "end": 70, "id": 13}, {"text": "in", "start": 71, "end": 73, "id": 14}, {"text": "both", "start": 74, "end": 78, "id": 15}, {"text": "kidneys", "start": 79, "end": 86, "id": 16}, {"text": "(", "start": 87, "end": 88, "id": 17}, {"text": "white", "start": 88, "end": 93, "id": 18}, {"text": "arrows", "start": 94, "end": 100, "id": 19}, {"text": ")", "start": 100, "end": 101, "id": 20}, {"text": ",", "start": 101, "end": 102, "id": 21}, {"text": "bulkiness", "start": 103, "end": 112, "id": 22}, {"text": "of", "start": 113, "end": 115, "id": 23}, {"text": "both", "start": 116, "end": 120, "id": 24}, {"text": "ovaries", "start": 121, "end": 128, "id": 25}, {"text": "(", "start": 129, "end": 130, "id": 26}, {"text": "black", "start": 130, "end": 135, "id": 27}, {"text": "arrows", "start": 136, "end": 142, "id": 28}, {"text": ")", "start": 142, "end": 143, "id": 29}, {"text": ",", "start": 143, "end": 144, "id": 30}, {"text": "and", "start": 145, "end": 148, "id": 31}, {"text": "permeative", "start": 149, "end": 159, "id": 32}, {"text": "osteolytic", "start": 160, "end": 170, "id": 33}, {"text": "lesions", "start": 171, "end": 178, "id": 34}, {"text": "in", "start": 179, "end": 181, "id": 35}, {"text": "the", "start": 182, "end": 185, "id": 36}, {"text": "bony", "start": 186, "end": 190, "id": 37}, {"text": "pelvis", "start": 191, "end": 197, "id": 38}, {"text": "(", "start": 198, "end": 199, "id": 39}, {"text": "arrowhead", "start": 199, "end": 208, "id": 40}, {"text": ")", "start": 208, "end": 209, "id": 41}]}
{"pdf_hash": "21d85f78a43128ed3d8169e87c2165659587c8f9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (a) Preoperative magnetic resonance (MRI) coronal T2-weighted imaging demonstrating sellar/suprasellar mass (diameter of 2 cm) with a heterogeneous signal, mainly hyperintense, compressing the optic chiasm and extended laterally toward the left cavernous sinus. (b and c) Preoperative magnetic resonance coronal and sagittal contrast-enhanced T1-weighted imaging showing an intense and diffuse enhancement. 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{"pdf_hash": "4fd976f697b82e21c04b86ba79120d984ec53601", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 A 4-week-old 3.5-kg boy. Imaging was performed using 6 ml of contrast medium and 3 ml saline by manual injection with 20 s scan delay. Volumetric imaging of an 8-cm chest range was acquired using a 320-MDCT scanner. Scan parameters were: tube voltage 80 kVp, tube current 60 mA, rotation time 0.35 s that resulted in 21 mAs. 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{"pdf_hash": "7bc12a0c91a48311422042176c622ef564a9799e", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Figure 4. A single slice of an OCT scan for different scan media. The dark region is the space above the surface of the agar plate. The red area is the agar. The yellow area is the mound as well as the bacteria on the surface. A) Dry Scan. B) Oil Immersion Scan of mound in (A). C) Dry Scan. D) Glycerol Immersed Scan of mound in (C). Brighter regions below mounds in (A) and (C) demonstrate lensing effects for dry scans. doi:10.1371/journal.pcbi.1002850.g004", "width": 984, "height": 334, "subcaptions": {"a": [89, 97, 98, 99, 100, 90, 101, 102, 103, 91, 51, 52, 53, 54, 55, 85, 86, 87, 88, 92], "b": [64, 65, 66, 67, 56, 57, 58, 59, 60, 61, 62, 63], "c": [96, 97, 98, 99, 68, 69, 70, 71, 72, 100, 101, 102, 103, 85, 86, 87, 88, 89, 94, 95], "d": [73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84]}, "subfigures": [{"id": "dc7e1254-9a21-4a82-a8e6-c39b252f96a6", "label": "a", "points": [[4.7, 6], [4.7, 329.3], [250.3, 329.3], [250.3, 6]], "color": "yellow"}, {"id": "72a14a8b-c43a-4c8e-8d24-d06304c1464f", "label": "b", "points": [[258.1, 7.5], [258.1, 326.2], [485, 326.2], [485, 7.5]], "color": "cyan"}, {"id": "0f3f6e8b-546e-416c-84ec-b0467fe93cc8", "label": "c", "points": [[491.2, 13.7], [491.2, 326.2], [730.6, 326.2], [730.6, 13.7]], "color": "magenta"}, {"id": "35d145d2-ef52-403f-8bbc-61c50638b714", "label": "d", "points": 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{"pdf_hash": "8012bf6110419f2ddfbe5503582da38fad87a7a0", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Figure 6. Chondrosarcoma of the cricoid cartilage in a 70-year-old man who presented with dyspnea and dysphagia. (a) Axial contrast-enhanced CT scan shows a large, hypoattenuating mass with coarse calcifications, characteristic of chondrosarcoma. The mass arises from the cricoid cartilage and leads to significant airway obstruction (arrow). (b) Endoscopic image (rotated so that the patient\u2019s right side is situated to the reader\u2019s right side) shows that the large tumor mass (arrowheads) is covered by intact mucosa. Note the significant airway obstruction (arrow). The mass arising from the cricoid cartilage is seen at the bottom of the image. E = epiglottis, F = false vocal cord. Histologic analysis revealed lowgrade chondrosarcoma.", "width": 610, "height": 930, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "b": [61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133]}, "subfigures": [{"id": "6d64cd1d-ef6e-488f-a0b1-9378cb1529d5", "label": "a", "points": [[570.6, 461.1], [570.6, 3.1], [3.6, 3.1], [3.6, 461.1]], "color": "yellow"}, {"id": "fcd08d9e-adea-4392-b6e9-f3e567ed6003", "label": "b", "points": [[8.6, 513.3], [8.6, 908.3], [570.6, 908.3], [570.6, 513.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", 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{"pdf_hash": "b3bff18eacf748379ba9d5b30eb43710453b978c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 CMR findings in wet beriberi. End-diastolic (A) and endsystolic (B) frames from short axis cine imaging demonstrate global hypokinesis of the left ventricle. (C.) LGE image shows borderline hyperenhancement of the basal lateral wall (arrow). (D) T2 mapping demonstrates significantly elevated myocardial T2 values suggestive of diffuse edema.", "width": 652, "height": 418, "subcaptions": {"a": [32, 8, 9, 10, 11, 12, 13, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "d": [64, 65, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "11a28845-5bb7-4462-b7fb-6fe066dda416", "label": "a", "points": [[24.7, 21.6], [24.7, 157.6], [323.4, 157.6], [323.4, 21.6]], "color": "yellow"}, {"id": "1952d83c-8cab-450a-a2b0-e8192e84bc1f", "label": "b", "points": [[335.8, 154.5], [335.8, 21.6], [633.5, 21.6], [633.5, 154.5]], "color": "cyan"}, {"id": "f4d41196-7b73-4164-a52b-ef6162f7b1a6", "label": "c", "points": [[326.5, 177.2], [326.5, 388.3], [25.8, 388.3], [25.8, 177.2]], "color": "magenta"}, {"id": "06267d72-61fa-4f4b-a3b7-f57c743247a7", "label": "d", "points": [[339.9, 382.1], [339.9, 180.3], [639.7, 180.3], [639.7, 382.1]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "CMR", "start": 9, "end": 12, "id": 2}, {"text": "findings", "start": 13, "end": 21, "id": 3}, {"text": "in", "start": 22, "end": 24, "id": 4}, {"text": "wet", "start": 25, "end": 28, "id": 5}, {"text": "beriberi", "start": 29, "end": 37, "id": 6}, {"text": ".", "start": 37, "end": 38, "id": 7}, {"text": "End", "start": 39, "end": 42, "id": 8}, {"text": "-", "start": 42, "end": 43, "id": 9}, {"text": "diastolic", "start": 43, "end": 52, "id": 10}, {"text": "(", "start": 53, "end": 54, "id": 11}, {"text": "A", "start": 54, "end": 55, "id": 12}, {"text": ")", "start": 55, "end": 56, "id": 13}, {"text": "and", "start": 57, "end": 60, "id": 14}, {"text": "endsystolic", "start": 61, "end": 72, "id": 15}, {"text": "(", "start": 73, "end": 74, "id": 16}, {"text": "B", "start": 74, "end": 75, "id": 17}, {"text": ")", "start": 75, "end": 76, "id": 18}, {"text": "frames", "start": 77, "end": 83, "id": 19}, {"text": "from", "start": 84, "end": 88, "id": 20}, {"text": "short", "start": 89, "end": 94, "id": 21}, {"text": "axis", "start": 95, "end": 99, "id": 22}, {"text": "cine", "start": 100, "end": 104, "id": 23}, {"text": "imaging", "start": 105, "end": 112, "id": 24}, {"text": "demonstrate", "start": 113, "end": 124, "id": 25}, {"text": "global", "start": 125, "end": 131, "id": 26}, {"text": "hypokinesis", "start": 132, "end": 143, "id": 27}, {"text": "of", "start": 144, "end": 146, "id": 28}, {"text": "the", "start": 147, "end": 150, "id": 29}, {"text": "left", "start": 151, "end": 155, "id": 30}, {"text": "ventricle", "start": 156, "end": 165, "id": 31}, {"text": ".", "start": 165, "end": 166, "id": 32}, {"text": "(", "start": 167, "end": 168, "id": 33}, {"text": "C.", "start": 168, "end": 170, "id": 34}, {"text": ")", "start": 170, "end": 171, "id": 35}, {"text": "LGE", "start": 172, "end": 175, "id": 36}, {"text": "image", "start": 176, "end": 181, "id": 37}, {"text": "shows", "start": 182, "end": 187, "id": 38}, {"text": "borderline", "start": 188, "end": 198, "id": 39}, {"text": "hyperenhancement", "start": 199, "end": 215, "id": 40}, {"text": "of", "start": 216, "end": 218, "id": 41}, {"text": "the", "start": 219, "end": 222, "id": 42}, {"text": "basal", "start": 223, "end": 228, "id": 43}, {"text": "lateral", "start": 229, "end": 236, "id": 44}, {"text": "wall", "start": 237, "end": 241, "id": 45}, {"text": "(", "start": 242, "end": 243, "id": 46}, {"text": "arrow", "start": 243, "end": 248, "id": 47}, {"text": ")", "start": 248, "end": 249, "id": 48}, {"text": ".", "start": 249, "end": 250, "id": 49}, {"text": "(", "start": 251, "end": 252, "id": 50}, {"text": "D", "start": 252, "end": 253, "id": 51}, {"text": ")", "start": 253, "end": 254, "id": 52}, {"text": "T2", "start": 255, "end": 257, "id": 53}, {"text": "mapping", "start": 258, "end": 265, "id": 54}, {"text": "demonstrates", "start": 266, "end": 278, "id": 55}, {"text": "significantly", "start": 279, "end": 292, "id": 56}, {"text": "elevated", "start": 293, "end": 301, "id": 57}, {"text": "myocardial", "start": 302, "end": 312, "id": 58}, {"text": "T2", "start": 313, "end": 315, "id": 59}, {"text": "values", "start": 316, "end": 322, "id": 60}, {"text": "suggestive", "start": 323, "end": 333, "id": 61}, {"text": "of", "start": 334, "end": 336, "id": 62}, {"text": "diffuse", "start": 337, "end": 344, "id": 63}, {"text": "edema", "start": 345, "end": 350, "id": 64}, {"text": ".", "start": 350, "end": 351, "id": 65}]}
{"pdf_hash": "a0049194c163d8142d5760b0d5cbfe55d82687c8", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Figure 6. (A, B) Images acquired with computed tomography using a slice thickness between 0.8 and 1.0 mm in 2 patients with dissecting aneurysms treated with stent-grafts. The stent wires measured between 1.71 and 2.05 mm; the voxel size was 0.68\u00d70.68\u00d70.68 mm3 and 0.78\u00d70.78\u00d70.78 mm3, respectively.", "width": 968, "height": 522, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "43867fd9-a84a-4d8b-a260-7bdd267172ec", "label": "a", "points": [[41.5, 24.5], [41.5, 497], [491.2, 497], [491.2, 24.5]], "color": "yellow"}, {"id": "459aac18-fffb-4c9c-ae20-8fffaafdffdd", "label": "a", "points": [[509.5, 29.1], [509.5, 506.2], [937.7, 506.2], [937.7, 29.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ",", "start": 12, "end": 13, "id": 5}, {"text": "B", "start": 14, "end": 15, "id": 6}, {"text": ")", "start": 15, "end": 16, "id": 7}, {"text": "Images", "start": 17, "end": 23, "id": 8}, {"text": "acquired", "start": 24, "end": 32, "id": 9}, {"text": "with", "start": 33, "end": 37, "id": 10}, {"text": "computed", "start": 38, "end": 46, "id": 11}, {"text": "tomography", "start": 47, "end": 57, "id": 12}, {"text": "using", "start": 58, "end": 63, "id": 13}, {"text": "a", "start": 64, "end": 65, "id": 14}, {"text": "slice", "start": 66, "end": 71, "id": 15}, {"text": "thickness", "start": 72, "end": 81, "id": 16}, {"text": "between", "start": 82, "end": 89, "id": 17}, {"text": "0.8", "start": 90, "end": 93, "id": 18}, {"text": "and", "start": 94, "end": 97, "id": 19}, {"text": "1.0", "start": 98, "end": 101, "id": 20}, {"text": "mm", "start": 102, "end": 104, "id": 21}, {"text": "in", "start": 105, "end": 107, "id": 22}, {"text": "2", "start": 108, "end": 109, "id": 23}, {"text": "patients", "start": 110, "end": 118, "id": 24}, {"text": "with", "start": 119, "end": 123, "id": 25}, {"text": "dissecting", "start": 124, "end": 134, "id": 26}, {"text": "aneurysms", "start": 135, "end": 144, "id": 27}, {"text": "treated", "start": 145, "end": 152, "id": 28}, {"text": "with", "start": 153, "end": 157, "id": 29}, {"text": "stent", "start": 158, "end": 163, "id": 30}, {"text": "-", "start": 163, "end": 164, "id": 31}, {"text": "grafts", "start": 164, "end": 170, "id": 32}, {"text": ".", "start": 170, "end": 171, "id": 33}, {"text": "The", "start": 172, "end": 175, "id": 34}, {"text": "stent", "start": 176, "end": 181, "id": 35}, {"text": "wires", "start": 182, "end": 187, "id": 36}, {"text": "measured", "start": 188, "end": 196, "id": 37}, {"text": "between", "start": 197, "end": 204, "id": 38}, {"text": "1.71", "start": 205, "end": 209, "id": 39}, {"text": "and", "start": 210, "end": 213, "id": 40}, {"text": "2.05", "start": 214, "end": 218, "id": 41}, {"text": "mm", "start": 219, "end": 221, "id": 42}, {"text": ";", "start": 221, "end": 222, "id": 43}, {"text": "the", "start": 223, "end": 226, "id": 44}, {"text": "voxel", "start": 227, "end": 232, "id": 45}, {"text": "size", "start": 233, "end": 237, "id": 46}, {"text": "was", "start": 238, "end": 241, "id": 47}, {"text": "0.68\u00d70.68\u00d70.68", "start": 242, "end": 256, "id": 48}, {"text": "mm3", "start": 257, "end": 260, "id": 49}, {"text": "and", "start": 261, "end": 264, "id": 50}, {"text": "0.78\u00d70.78\u00d70.78", "start": 265, "end": 279, "id": 51}, {"text": "mm3", "start": 280, "end": 283, "id": 52}, {"text": ",", "start": 283, "end": 284, "id": 53}, {"text": "respectively", "start": 285, "end": 297, "id": 54}, {"text": ".", "start": 297, "end": 298, "id": 55}]}
{"pdf_hash": "9ef1114e636c5b62f98923d4adfb086562270ca2", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "FIGURE 1. Statistical parametric maps of the effect of body size (lean compared with obese subjects) on regional cerebral blood flow in response to the consumption of a meal at the level of the left dorsolateral prefrontal cortex (peak voxel: x \u0483 \u048034, y \u0483 58, z \u0483 14; P \u0483 0.00009). Horizontal (bottom), coronal (upper right), and sagittal (upper left) sections. Coordinates (x, y, and z) were from the Montreal Neurological Institute standard brain, such that x is the distance in millimeters to the right (\u047f) or left (-) of midline, y is the distance in millimeters anterior (\u047f) or posterior (-) to the anterior commissure, and z is the distance in millimeters superior (\u047f) or inferior (-) to a horizontal plane through the anterior and posterior commissures. 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{"pdf_hash": "57e88ada41345f7d1607f8fdf892bba4107fc20e", "fig_key": "Figure8", "fig_uri": "5-Figure8-1.png", "text": "Fig. 8 (a) Axial MDCT image shows the fracture extending through the foramen transversarium (white arrow). (b) Coronal CT angiogram MIP image demonstrates sudden cutoff of the left vertebral artery consistent with dissection (black arrow), which is also seen on the axial T2-weighted image (c) as loss of flow void (white arrow)", "width": 1018, "height": 368, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "c": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "c9161148-ac98-4ac8-b615-f92ae4cd50d5", "label": "a", "points": [[0.9, 4.6], [0.9, 356.8], [327.3, 356.8], [327.3, 4.6]], "color": "yellow"}, {"id": "b3419600-0932-41aa-81e2-ce42cf8b967d", "label": "b", "points": [[341.8, -0.3], [341.8, 366.4], [513.9, 366.4], [513.9, -0.3]], "color": "cyan"}, {"id": "e0492a3a-df37-46ce-941e-b33777c87a11", "label": "c", "points": [[530, 3], [530, 361.6], [1010.8, 361.6], [1010.8, 3]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "8", "start": 5, "end": 6, "id": 2}, {"text": "(", "start": 7, "end": 8, "id": 3}, {"text": "a", "start": 8, "end": 9, "id": 4}, {"text": ")", "start": 9, "end": 10, "id": 5}, {"text": "Axial", "start": 11, "end": 16, "id": 6}, {"text": "MDCT", "start": 17, "end": 21, "id": 7}, {"text": "image", "start": 22, "end": 27, "id": 8}, {"text": "shows", "start": 28, "end": 33, "id": 9}, {"text": "the", "start": 34, "end": 37, "id": 10}, {"text": "fracture", "start": 38, "end": 46, "id": 11}, {"text": "extending", "start": 47, "end": 56, "id": 12}, {"text": "through", "start": 57, "end": 64, "id": 13}, {"text": "the", "start": 65, "end": 68, "id": 14}, {"text": "foramen", "start": 69, "end": 76, "id": 15}, {"text": "transversarium", "start": 77, "end": 91, "id": 16}, {"text": "(", "start": 92, "end": 93, "id": 17}, {"text": "white", "start": 93, "end": 98, "id": 18}, {"text": "arrow", "start": 99, "end": 104, "id": 19}, {"text": ")", "start": 104, "end": 105, "id": 20}, {"text": ".", "start": 105, "end": 106, "id": 21}, {"text": "(", "start": 107, "end": 108, "id": 22}, {"text": "b", "start": 108, "end": 109, "id": 23}, {"text": ")", "start": 109, "end": 110, "id": 24}, {"text": "Coronal", "start": 111, "end": 118, "id": 25}, {"text": "CT", "start": 119, "end": 121, "id": 26}, {"text": "angiogram", "start": 122, "end": 131, "id": 27}, {"text": "MIP", "start": 132, "end": 135, "id": 28}, {"text": "image", "start": 136, "end": 141, "id": 29}, {"text": "demonstrates", "start": 142, "end": 154, "id": 30}, {"text": "sudden", "start": 155, "end": 161, "id": 31}, {"text": "cutoff", "start": 162, "end": 168, "id": 32}, {"text": "of", "start": 169, "end": 171, "id": 33}, {"text": "the", "start": 172, "end": 175, "id": 34}, {"text": "left", "start": 176, "end": 180, "id": 35}, {"text": "vertebral", "start": 181, "end": 190, "id": 36}, {"text": "artery", "start": 191, "end": 197, "id": 37}, {"text": "consistent", "start": 198, "end": 208, "id": 38}, {"text": "with", "start": 209, "end": 213, "id": 39}, {"text": "dissection", "start": 214, "end": 224, "id": 40}, {"text": "(", "start": 225, "end": 226, "id": 41}, {"text": "black", "start": 226, "end": 231, "id": 42}, {"text": "arrow", "start": 232, "end": 237, "id": 43}, {"text": ")", "start": 237, "end": 238, "id": 44}, {"text": ",", "start": 238, "end": 239, "id": 45}, {"text": "which", "start": 240, "end": 245, "id": 46}, {"text": "is", "start": 246, "end": 248, "id": 47}, {"text": "also", "start": 249, "end": 253, "id": 48}, {"text": "seen", "start": 254, "end": 258, "id": 49}, {"text": "on", "start": 259, "end": 261, "id": 50}, {"text": "the", "start": 262, "end": 265, "id": 51}, {"text": "axial", "start": 266, "end": 271, "id": 52}, {"text": "T2-weighted", "start": 272, "end": 283, "id": 53}, {"text": "image", "start": 284, "end": 289, "id": 54}, {"text": "(", "start": 290, "end": 291, "id": 55}, {"text": "c", "start": 291, "end": 292, "id": 56}, {"text": ")", "start": 292, "end": 293, "id": 57}, {"text": "as", "start": 294, "end": 296, "id": 58}, {"text": "loss", "start": 297, "end": 301, "id": 59}, {"text": "of", "start": 302, "end": 304, "id": 60}, {"text": "flow", "start": 305, "end": 309, "id": 61}, {"text": "void", "start": 310, "end": 314, "id": 62}, {"text": "(", "start": 315, "end": 316, "id": 63}, {"text": "white", "start": 316, "end": 321, "id": 64}, {"text": "arrow", "start": 322, "end": 327, "id": 65}, {"text": ")", "start": 327, "end": 328, "id": 66}]}
{"pdf_hash": "82804cc5e58755165154740ab62ed8d4bbb64c85", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1 a AP Radiograph. The inferior vestigial ribs on the concave side appear too weak for VEPTR attachment. b 3D reconstruction of CT of chest and spine. The scan enables better visualization of the vestigial 11th and 12th ribs, which appear to be thick enough to carry the load of the VEPTR devices. c The coronal reconstruction of the CT scan. Note the anomalous insertion of the hemi-diaphragm proximally to the fused ribs on the concave side. This CT scan ruled out attachment of the hemidiaphragm to soft tissue below the fused ribs, a flail hemidiaphragm, which would have required a completely different operative strategy. d Supine lateral radiograph. Note kyphosis. It is not severe enough to warrant use of VEPTR II. 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{"pdf_hash": "48633b8749df9abbc7f7b5273ad0ca07f443042d", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Contrast enhanced computed tomography. Superior mesenteric vein (white arrow) was on the left side of the superior mesenteric artery on axial CT image (a). Axial CT images showing polysplenia (white arrow) (b). Coronal reformatted CT images showing dilated appendix (2 cm) and 2 cm fecalith (white arrow) and a few enlarged lymph node in mesentery (black arrows) (c), Free air and focal mesenteric stranding were around the proximal part of appendix on axial CT image (white arrow) (d).", "width": 650, "height": 564, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "c": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80], "d": [81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105]}, "subfigures": [{"id": "5eede57d-b9c5-4133-b0b0-0fbe826bf376", "label": "a", "points": [[-0.5, 1.9], [-0.5, 200.1], [311.7, 200.1], [311.7, 1.9]], "color": "yellow"}, {"id": "71b356d9-3322-4da8-af06-4eaba999db7d", "label": "b", "points": [[334.3, 1.9], 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{"pdf_hash": "8633e15628b8ba6f9dceb9778621acffa10eedc1", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Figure 6. Transverse cross sections of sciatic nerves, 12 weeks after injury. Observe the decreased number of myelinated fibers in the avulsion group as compared to reimplanted groups. (A) control; (B) avulsion; (C) avulsion + sealant; (D) avulsion + sealant + cells. Scale bar = 10 \u00b5m.", "width": 1162, "height": 908, "subcaptions": {"a": [32, 33, 34, 35, 36], "b": [37, 38, 39, 40, 41], "c": [42, 43, 44, 45, 46, 47, 48], "d": [49, 50, 51, 52, 53, 54, 55, 56, 57]}, "subfigures": [{"id": "5b3f95d2-c6f3-41c1-b825-08dff27cb852", "label": "a", "points": [[0.9, 36.7], [0.9, 460.8], [571.8, 460.8], [571.8, 36.7]], "color": "yellow"}, {"id": "8172caa2-394a-4721-be87-754b8284039c", "label": "b", "points": [[592, 34.9], [592, 466.3], [1159.3, 466.3], [1159.3, 34.9]], "color": "cyan"}, {"id": "453e43a4-c33e-4577-8800-656df1cdfdaf", "label": "c", "points": [[-0.9, 473.6], [-0.9, 903.2], [573.7, 903.2], [573.7, 473.6]], "color": "magenta"}, {"id": "2525b2aa-1049-4ad5-ac31-43e77f2a5e21", "label": "d", "points": [[588.4, 481], [588.4, 903.2], [1155.6, 903.2], [1155.6, 481]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Transverse", "start": 10, "end": 20, "id": 3}, {"text": "cross", "start": 21, "end": 26, "id": 4}, {"text": "sections", "start": 27, "end": 35, "id": 5}, {"text": "of", "start": 36, "end": 38, "id": 6}, {"text": "sciatic", "start": 39, "end": 46, "id": 7}, {"text": "nerves", "start": 47, "end": 53, "id": 8}, {"text": ",", "start": 53, "end": 54, "id": 9}, {"text": "12", "start": 55, "end": 57, "id": 10}, {"text": "weeks", "start": 58, "end": 63, "id": 11}, {"text": "after", "start": 64, "end": 69, "id": 12}, {"text": "injury", "start": 70, "end": 76, "id": 13}, {"text": ".", "start": 76, "end": 77, "id": 14}, {"text": "Observe", "start": 78, "end": 85, "id": 15}, {"text": "the", "start": 86, "end": 89, "id": 16}, {"text": "decreased", "start": 90, "end": 99, "id": 17}, {"text": "number", "start": 100, "end": 106, "id": 18}, {"text": "of", "start": 107, "end": 109, "id": 19}, {"text": "myelinated", "start": 110, "end": 120, "id": 20}, {"text": "fibers", "start": 121, "end": 127, "id": 21}, {"text": "in", "start": 128, "end": 130, "id": 22}, {"text": "the", "start": 131, "end": 134, "id": 23}, {"text": "avulsion", "start": 135, "end": 143, "id": 24}, {"text": "group", "start": 144, "end": 149, "id": 25}, {"text": "as", "start": 150, "end": 152, "id": 26}, {"text": "compared", "start": 153, "end": 161, "id": 27}, {"text": "to", "start": 162, "end": 164, "id": 28}, {"text": "reimplanted", "start": 165, "end": 176, "id": 29}, {"text": "groups", "start": 177, "end": 183, "id": 30}, {"text": ".", "start": 183, "end": 184, "id": 31}, {"text": "(", "start": 185, "end": 186, "id": 32}, {"text": "A", "start": 186, "end": 187, "id": 33}, {"text": ")", "start": 187, "end": 188, "id": 34}, {"text": "control", "start": 189, "end": 196, "id": 35}, {"text": ";", "start": 196, "end": 197, "id": 36}, {"text": "(", "start": 198, "end": 199, "id": 37}, {"text": "B", "start": 199, "end": 200, "id": 38}, {"text": ")", "start": 200, "end": 201, "id": 39}, {"text": "avulsion", "start": 202, "end": 210, "id": 40}, {"text": ";", "start": 210, "end": 211, "id": 41}, {"text": "(", "start": 212, "end": 213, "id": 42}, {"text": "C", "start": 213, "end": 214, "id": 43}, {"text": ")", "start": 214, "end": 215, "id": 44}, {"text": "avulsion", "start": 216, "end": 224, "id": 45}, {"text": "+", "start": 225, "end": 226, "id": 46}, {"text": "sealant", "start": 227, "end": 234, "id": 47}, {"text": ";", "start": 234, "end": 235, "id": 48}, {"text": "(", "start": 236, "end": 237, "id": 49}, {"text": "D", "start": 237, "end": 238, "id": 50}, {"text": ")", "start": 238, "end": 239, "id": 51}, {"text": "avulsion", "start": 240, "end": 248, "id": 52}, {"text": "+", "start": 249, "end": 250, "id": 53}, {"text": "sealant", "start": 251, "end": 258, "id": 54}, {"text": "+", "start": 259, "end": 260, "id": 55}, {"text": "cells", "start": 261, "end": 266, "id": 56}, {"text": ".", "start": 266, "end": 267, "id": 57}, {"text": "Scale", "start": 268, "end": 273, "id": 58}, {"text": "bar", "start": 274, "end": 277, "id": 59}, {"text": "=", "start": 278, "end": 279, "id": 60}, {"text": "10", "start": 280, "end": 282, "id": 61}, {"text": "\u00b5m", "start": 283, "end": 285, "id": 62}, {"text": ".", "start": 285, "end": 286, "id": 63}]}
{"pdf_hash": "a7eedfb56be5accf28dca7639c98a26d894c7301", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. Coronal (A) and axial (B) images incidentally show multiple spleniculi (*) seen through the left upper quadrant.", "width": 1294, "height": 728, "subcaptions": {"a": [3, 4, 5, 6, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26]}, "subfigures": [{"id": "29eec655-0454-42f0-ba42-ef7ff6dc6f4f", "label": "a", "points": [[7.2, 8.2], [7.2, 699.2], [583.7, 699.2], [583.7, 8.2]], "color": "yellow"}, {"id": "2fee537e-a20f-4a28-a930-a1ff42c9f7bf", "label": "b", "points": [[593.9, 8.2], [593.9, 703.2], [1286.9, 703.2], [1286.9, 8.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Coronal", "start": 10, "end": 17, "id": 3}, {"text": "(", "start": 18, "end": 19, "id": 4}, {"text": "A", "start": 19, "end": 20, "id": 5}, {"text": ")", "start": 20, "end": 21, "id": 6}, {"text": "and", "start": 22, "end": 25, "id": 7}, {"text": "axial", "start": 26, "end": 31, "id": 8}, {"text": "(", "start": 32, "end": 33, "id": 9}, {"text": "B", "start": 33, "end": 34, "id": 10}, {"text": ")", "start": 34, "end": 35, "id": 11}, {"text": "images", "start": 36, "end": 42, "id": 12}, {"text": "incidentally", "start": 43, "end": 55, "id": 13}, {"text": "show", "start": 56, "end": 60, "id": 14}, {"text": "multiple", "start": 61, "end": 69, "id": 15}, {"text": "spleniculi", "start": 70, "end": 80, "id": 16}, {"text": "(", "start": 81, "end": 82, "id": 17}, {"text": "*", "start": 82, "end": 83, "id": 18}, {"text": ")", "start": 83, "end": 84, "id": 19}, {"text": "seen", "start": 85, "end": 89, "id": 20}, {"text": "through", "start": 90, "end": 97, "id": 21}, {"text": "the", "start": 98, "end": 101, "id": 22}, {"text": "left", "start": 102, "end": 106, "id": 23}, {"text": "upper", "start": 107, "end": 112, "id": 24}, {"text": "quadrant", "start": 113, "end": 121, "id": 25}, {"text": ".", "start": 121, "end": 122, "id": 26}]}
{"pdf_hash": "415a1f12b7edfff1e381906dfbd0f9fe6c24cdb7", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Cytoplasmatic/nuclear expression of MT-I/II (A) and nuclear expression of Ki-67 antigen (B) in cells of BCC", "width": 632, "height": 870, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 25, 26, 27, 28], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "6102cc2a-088e-429e-bab6-b0ae4c3d927f", "label": "a", "points": [[1, 5.8], [1, 418.8], [631, 418.8], [631, 5.8]], "color": "yellow"}, {"id": "3c70f151-1cd3-4993-92ef-c1d62a881df8", "label": "b", "points": [[4, 439.8], [4, 866.9], [628, 866.9], [628, 439.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Cytoplasmatic", "start": 10, "end": 23, "id": 3}, {"text": "/", "start": 23, "end": 24, "id": 4}, {"text": "nuclear", "start": 24, "end": 31, "id": 5}, {"text": "expression", "start": 32, "end": 42, "id": 6}, {"text": "of", "start": 43, "end": 45, "id": 7}, {"text": "MT", "start": 46, "end": 48, "id": 8}, {"text": "-", "start": 48, "end": 49, "id": 9}, {"text": "I", "start": 49, "end": 50, "id": 10}, {"text": "/", "start": 50, "end": 51, "id": 11}, {"text": "II", "start": 51, "end": 53, "id": 12}, {"text": "(", "start": 54, "end": 55, "id": 13}, {"text": "A", "start": 55, "end": 56, "id": 14}, {"text": ")", "start": 56, "end": 57, "id": 15}, {"text": "and", "start": 58, "end": 61, "id": 16}, {"text": "nuclear", "start": 62, "end": 69, "id": 17}, {"text": "expression", "start": 70, "end": 80, "id": 18}, {"text": "of", "start": 81, "end": 83, "id": 19}, {"text": "Ki-67", "start": 84, "end": 89, "id": 20}, {"text": "antigen", "start": 90, "end": 97, "id": 21}, {"text": "(", "start": 98, "end": 99, "id": 22}, {"text": "B", "start": 99, "end": 100, "id": 23}, {"text": ")", "start": 100, "end": 101, "id": 24}, {"text": "in", "start": 102, "end": 104, "id": 25}, {"text": "cells", "start": 105, "end": 110, "id": 26}, {"text": "of", "start": 111, "end": 113, "id": 27}, {"text": "BCC", "start": 114, "end": 117, "id": 28}]}
{"pdf_hash": "67427faf0d8f556ee39700b9c0eb5fa278805b33", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5 Surgery of the retroperitoneal peripancreatic unicentric Castleman disease in Case 2. A: The lesion was located below and behind the transverse mesocolon with a volume of 3.5 cm \u00d7 3 cm \u00d7 3 cm. Intraoperative ultrasonography indicated that the tumor had an abundant blood supply, and its right side was close to the inferior mesenteric artery and vein; B: Image of the free tumor; C: The tumor was completely excised.", "width": 1278, "height": 260, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "b": [65, 66, 67, 68, 69, 70, 71, 72], "c": [73, 74, 75, 76, 77, 78, 79, 80]}, "subfigures": [{"id": "42987171-b28d-4c37-89a6-d372bc28b0a9", "label": "a", "points": [[4, 6.1], [4, 258.5], [424, 258.5], [424, 6.1]], "color": "yellow"}, {"id": "4e48d219-efc9-4771-8f4b-9636390a9ba2", "label": "b", "points": [[434.1, 2], [434.1, 256.4], [846, 256.4], [846, 2]], "color": "cyan"}, {"id": "e4700960-8e08-4c60-8501-4810d05a5903", "label": "c", "points": [[862.2, 0], [862.2, 258.5], [1276.1, 258.5], [1276.1, 0]], "color": 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{"pdf_hash": "be6ade7549b9dc979c3d1bbadf649e7b99484a96", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Fig 6. Kidney injury molecule 1 (KIM-1) immunohistochemical staining of sections from cats with various kidney diseases. (A) Cat with hypoperfusion, no prior kidney disease, positive KIM-1 urine, note tubular staining in the OSOM. Inset: Preincubation of antibody with KIM-1 peptide abrogates staining (12.59 magnification). (B) Cat with acute kidney injury because of bite wounds, sepsis and hypotension, positive urine KIM-1 result. Note staining of individual tubules. (C) Cat with acute exacerbation of chronic renal disease. Renal fibrosis and tubular necrosis were present at postmortem. Urine KIM-1 result was positive on admission. There is sparse KIM-1 staining in individual proximal tubular cells and lumen. (D) Cat with glomerulonephritis and interstitial nephritis because of chronic urolithiasis, negative urine KIM-1 result. 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{"pdf_hash": "9f5d29e4665cb2514cd26c23af52d95e11b45afb", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 (A) Horizontal view and (B) (frontal view): Chest CT showing anterior mediastinal tumor measuring 50 \u00d7 48 \u00d7 20 mm with ring calcification. (C) Type B1 thymoma (right side) outside the ring calcification (left side). (D) Horizontal view and (E) frontal view: Enhanced chest CT revealed the anterior mediastinal tumor measuring 50 \u00d7 40 \u00d7 20 mm with ring calcification, which was suspected to have invaded the superior vena cava (arrow). 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{"pdf_hash": "b314d5a973dce96333a2225fb11ff962562212d2", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Figure 6. (a) SEM backscattered electron micrograph and (b) energy dispersive X-ray spectroscopy (EDS) map of cubic carbide phases in composite 1 interruptedly sintered at 1345 \u2022 C.", "width": 630, "height": 666, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9], "b": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36]}, "subfigures": [{"id": "4691553a-074d-4322-bbec-4c879e504b47", "label": "a", "points": [[0, 2.7], [0, 472.7], [628, 472.7], [628, 2.7]], "color": "yellow"}, {"id": "e4b175f0-8afc-43f5-b424-fb399ebed905", "label": "b", "points": [[9, 512], [9, 665], [624, 665], [624, 512]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "SEM", "start": 14, "end": 17, "id": 6}, {"text": "backscattered", "start": 18, "end": 31, "id": 7}, {"text": "electron", "start": 32, "end": 40, "id": 8}, {"text": "micrograph", "start": 41, "end": 51, "id": 9}, {"text": "and", "start": 52, "end": 55, "id": 10}, {"text": "(", "start": 56, "end": 57, "id": 11}, {"text": "b", "start": 57, "end": 58, "id": 12}, {"text": ")", "start": 58, "end": 59, "id": 13}, {"text": "energy", "start": 60, "end": 66, "id": 14}, {"text": "dispersive", "start": 67, "end": 77, "id": 15}, {"text": "X", "start": 78, "end": 79, "id": 16}, {"text": "-", "start": 79, "end": 80, "id": 17}, {"text": "ray", "start": 80, "end": 83, "id": 18}, {"text": "spectroscopy", "start": 84, "end": 96, "id": 19}, {"text": "(", "start": 97, "end": 98, "id": 20}, {"text": "EDS", "start": 98, "end": 101, "id": 21}, {"text": ")", "start": 101, "end": 102, "id": 22}, {"text": "map", "start": 103, "end": 106, "id": 23}, {"text": "of", "start": 107, "end": 109, "id": 24}, {"text": "cubic", "start": 110, "end": 115, "id": 25}, {"text": "carbide", "start": 116, "end": 123, "id": 26}, {"text": "phases", "start": 124, "end": 130, "id": 27}, {"text": "in", "start": 131, "end": 133, "id": 28}, {"text": "composite", "start": 134, "end": 143, "id": 29}, {"text": "1", "start": 144, "end": 145, "id": 30}, {"text": "interruptedly", "start": 146, "end": 159, "id": 31}, {"text": "sintered", "start": 160, "end": 168, "id": 32}, {"text": "at", "start": 169, "end": 171, "id": 33}, {"text": "1345", "start": 172, "end": 176, "id": 34}, {"text": "\u2022", "start": 177, "end": 178, "id": 35}, {"text": "C.", "start": 179, "end": 181, "id": 36}]}
{"pdf_hash": "a4ad66f3046d34f63c0a9ea20dcaef633036ea14", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Fig. 4 Dynamic contrastenhanced CT (perfusion CT) blood flow parametric map (a); 2D image (b); segmented and thresholded image (c) for fractal analysis", "width": 898, "height": 518, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23], "c": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "9ef2a393-701a-4978-b7b9-793a7ddf7e2d", "label": "a", "points": [[33.3, 28.4], [33.3, 513.6], [589.5, 513.6], [589.5, 28.4]], "color": "yellow"}, {"id": "ad6bce11-6385-4f49-ad3d-0e5fbb39b238", "label": "b", "points": [[596.6, 31.2], [596.6, 266.7], [893.1, 266.7], [893.1, 31.2]], "color": "cyan"}, {"id": "0a9c4153-7bc2-40dd-871c-f4a6c83fbe92", "label": "c", "points": [[598, 269.6], [598, 510.7], [893.1, 510.7], [893.1, 269.6]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Dynamic", "start": 7, "end": 14, "id": 3}, {"text": "contrastenhanced", "start": 15, "end": 31, "id": 4}, {"text": "CT", "start": 32, "end": 34, "id": 5}, {"text": "(", "start": 35, "end": 36, "id": 6}, {"text": "perfusion", "start": 36, "end": 45, "id": 7}, {"text": "CT", "start": 46, "end": 48, "id": 8}, {"text": ")", "start": 48, "end": 49, "id": 9}, {"text": "blood", "start": 50, "end": 55, "id": 10}, {"text": "flow", "start": 56, "end": 60, "id": 11}, {"text": "parametric", "start": 61, "end": 71, "id": 12}, {"text": "map", "start": 72, "end": 75, "id": 13}, {"text": "(", "start": 76, "end": 77, "id": 14}, {"text": "a", "start": 77, "end": 78, "id": 15}, {"text": ")", "start": 78, "end": 79, "id": 16}, {"text": ";", "start": 79, "end": 80, "id": 17}, {"text": "2D", "start": 81, "end": 83, "id": 18}, {"text": "image", "start": 84, "end": 89, "id": 19}, {"text": "(", "start": 90, "end": 91, "id": 20}, {"text": "b", "start": 91, "end": 92, "id": 21}, {"text": ")", "start": 92, "end": 93, "id": 22}, {"text": ";", "start": 93, "end": 94, "id": 23}, {"text": "segmented", "start": 95, "end": 104, "id": 24}, {"text": "and", "start": 105, "end": 108, "id": 25}, {"text": "thresholded", "start": 109, "end": 120, "id": 26}, {"text": "image", "start": 121, "end": 126, "id": 27}, {"text": "(", "start": 127, "end": 128, "id": 28}, {"text": "c", "start": 128, "end": 129, "id": 29}, {"text": ")", "start": 129, "end": 130, "id": 30}, {"text": "for", "start": 131, "end": 134, "id": 31}, {"text": "fractal", "start": 135, "end": 142, "id": 32}, {"text": "analysis", "start": 143, "end": 151, "id": 33}]}
{"pdf_hash": "173931f4f2b5331e5fbe508ae2c94e600cdc190b", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 VOI delineation in a 77-year-old patient with a large HCC of the right lobe associated with two small lesions of the left lobe who underwent treatment intensification (boosted). a Initial CT slice shows heterogeneous HCC of 12.3 cm with a central area of necrosis. b, d MAA SPECT/CT with high uptake and a hypofixing area: b VOI delineation for the tumour; d VOI delineation for the injected liver. 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{"pdf_hash": "c51969784f7e564684103a6812c818915b2ef832", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Features of proheads. (A) Low-resolution image of proheads (derivative filtered). (B) Top view of the pseudoatomic structure of \u03a629. Dashed lines outline two complex pentameric features: (i) lines in blue connect the icosahedral vertices, (ii) the red pentamer is limited by the protruding domains of the monomers. The latter is similar in size to the former feature, but slightly rotated. (C) High-resolution image of a prohead lying on its side, imaging force 130 pN. (D) Same for upright prohead. The dotted line marks the cross-section shown in F. (E) Size distribution of observed pentamer sides including tip convolution (N \u00bc 12, SD \u00bc 1.6 nm). 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{"pdf_hash": "7fcef968229c779e00e69fa3ec432cb7a8442a44", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. MRI taken after initial radiograph. Coronal T1-weighted image (left), T2*-weighted image (middle), and T2-weighted image (right).", "width": 1270, "height": 402, "subcaptions": {"a": [10, 11, 12, 13, 14, 15], "b": [17, 18, 19, 20, 21, 22, 23, 24], "c": [25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "9c9078eb-bb21-434d-9f4b-4825d8e1e385", "label": "a", "points": [[14.6, 15.8], [14.6, 399], [399.8, 399], [399.8, 15.8]], "color": "yellow"}, {"id": "6ebd0cc9-6429-4459-b0d3-b8cdf2f922c6", "label": "b", "points": [[454, 9.8], [454, 389], [827.2, 389], [827.2, 9.8]], "color": "cyan"}, {"id": "9bee8a17-8305-406d-84f2-dbc6f41ea58e", "label": "c", "points": [[883.4, 9.8], [883.4, 389], [1266.6, 389], [1266.6, 9.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "MRI", "start": 8, "end": 11, "id": 4}, {"text": "taken", "start": 12, "end": 17, "id": 5}, {"text": "after", "start": 18, "end": 23, "id": 6}, {"text": "initial", "start": 24, "end": 31, "id": 7}, {"text": "radiograph", "start": 32, "end": 42, "id": 8}, {"text": ".", "start": 42, "end": 43, "id": 9}, {"text": "Coronal", "start": 44, "end": 51, "id": 10}, {"text": "T1-weighted", "start": 52, "end": 63, "id": 11}, {"text": "image", "start": 64, "end": 69, "id": 12}, {"text": "(", "start": 70, "end": 71, "id": 13}, {"text": "left", "start": 71, "end": 75, "id": 14}, {"text": ")", "start": 75, "end": 76, "id": 15}, {"text": ",", "start": 76, "end": 77, "id": 16}, {"text": "T2", "start": 78, "end": 80, "id": 17}, {"text": "*", "start": 80, "end": 81, "id": 18}, {"text": "-weighted", "start": 81, "end": 90, "id": 19}, {"text": "image", "start": 91, "end": 96, "id": 20}, {"text": "(", "start": 97, "end": 98, "id": 21}, {"text": "middle", "start": 98, "end": 104, "id": 22}, {"text": ")", "start": 104, "end": 105, "id": 23}, {"text": ",", "start": 105, "end": 106, "id": 24}, {"text": "and", "start": 107, "end": 110, "id": 25}, {"text": "T2-weighted", "start": 111, "end": 122, "id": 26}, {"text": "image", "start": 123, "end": 128, "id": 27}, {"text": "(", "start": 129, "end": 130, "id": 28}, {"text": "right", "start": 130, "end": 135, "id": 29}, {"text": ")", "start": 135, "end": 136, "id": 30}, {"text": ".", "start": 136, "end": 137, "id": 31}]}
{"pdf_hash": "cd91bd8771f0e442c44078e996fba140a9aa3087", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Fundus images from the left and right eyes taken 4 months after treatment. 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{"pdf_hash": "3dd0472b5e0484edaffb2e45dc1ed2b98ac50152", "fig_key": "Figure7", "fig_uri": "15-Figure7-1.png", "text": "Fig 7. One 2D slice reconstructed from one rat data scanned from a micro CT. (A): FDK with Ram-Lak Filter; (B): OSEM with linear interpolation based FSNP; (C): OSEM with blob based FSNP. 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{"pdf_hash": "2a1a08a69ed96b375d157ed8c1c5820a9721e3b7", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "FIG. 4. An example coronal slice (top) containing a cross-section of the left main shows that SENSE images with 6-fold uniform undersampling (right) suffers from noise amplification, whereas the left main is clearly visualized using B1-weighted LOST with 6-fold random undersampling (left). 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{"pdf_hash": "0eb5ca605a3442c9bad3c2f6482b530bcb87f265", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 18F-FDG PET-CT brain scan. a 3D fused PET-CT sagittal slice and MIP reconstruction show increased metabolism in both cerebellar hemispheres. b 3D fused PET-CT axial slices. c Whole-brain axial slices", "width": 1374, "height": 858, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39], "c": [40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "0114e768-60f7-46f2-9ee1-7abc42fbac14", "label": "a", "points": [[12, 30], [12, 425.1], [667.5, 425.1], [667.5, 30]], "color": "yellow"}, {"id": "5ed9e5d3-2fd1-49c8-a81a-0e241b07642a", "label": "b", "points": [[7.7, 444.6], [7.7, 850.5], [680.5, 850.5], [680.5, 444.6]], "color": "cyan"}, {"id": "4f6feff5-4e05-4193-9d30-5ee54e5b8f14", "label": "c", "points": [[708.8, 30], [708.8, 839.6], [1359.9, 839.6], [1359.9, 30]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "18F", "start": 7, "end": 10, "id": 3}, {"text": "-", "start": 10, "end": 11, "id": 4}, {"text": "FDG", "start": 11, "end": 14, "id": 5}, {"text": "PET", "start": 15, "end": 18, "id": 6}, {"text": "-", "start": 18, "end": 19, "id": 7}, {"text": "CT", "start": 19, "end": 21, "id": 8}, {"text": "brain", "start": 22, "end": 27, "id": 9}, {"text": "scan", "start": 28, "end": 32, "id": 10}, {"text": ".", "start": 32, "end": 33, "id": 11}, {"text": "a", "start": 34, "end": 35, "id": 12}, {"text": "3D", "start": 36, "end": 38, "id": 13}, {"text": "fused", "start": 39, "end": 44, "id": 14}, {"text": "PET", "start": 45, "end": 48, "id": 15}, {"text": "-", "start": 48, "end": 49, "id": 16}, {"text": "CT", "start": 49, "end": 51, "id": 17}, {"text": "sagittal", "start": 52, "end": 60, "id": 18}, {"text": "slice", "start": 61, "end": 66, "id": 19}, {"text": "and", "start": 67, "end": 70, "id": 20}, {"text": "MIP", "start": 71, "end": 74, "id": 21}, {"text": "reconstruction", "start": 75, "end": 89, "id": 22}, {"text": "show", "start": 90, "end": 94, "id": 23}, {"text": "increased", "start": 95, "end": 104, "id": 24}, {"text": "metabolism", "start": 105, "end": 115, "id": 25}, {"text": "in", "start": 116, "end": 118, "id": 26}, {"text": "both", "start": 119, "end": 123, "id": 27}, {"text": "cerebellar", "start": 124, "end": 134, "id": 28}, {"text": "hemispheres", "start": 135, "end": 146, "id": 29}, {"text": ".", "start": 146, "end": 147, "id": 30}, {"text": "b", "start": 148, "end": 149, "id": 31}, {"text": "3D", "start": 150, "end": 152, "id": 32}, {"text": "fused", "start": 153, "end": 158, "id": 33}, {"text": "PET", "start": 159, "end": 162, "id": 34}, {"text": "-", "start": 162, "end": 163, "id": 35}, {"text": "CT", "start": 163, "end": 165, "id": 36}, {"text": "axial", "start": 166, "end": 171, "id": 37}, {"text": "slices", "start": 172, "end": 178, "id": 38}, {"text": ".", "start": 178, "end": 179, "id": 39}, {"text": "c", "start": 180, "end": 181, "id": 40}, {"text": "Whole", "start": 182, "end": 187, "id": 41}, {"text": "-", "start": 187, "end": 188, "id": 42}, {"text": "brain", "start": 188, "end": 193, "id": 43}, {"text": "axial", "start": 194, "end": 199, "id": 44}, {"text": "slices", "start": 200, "end": 206, "id": 45}]}
{"pdf_hash": "e533aad3410ab346de8a53ff6dd8611430d9edf5", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1. (A) Magnetic resonance imaging of renal mass with no intravenous contrast, demonstrating approximately 5.7 cm 9 5.8 cm 9 6.6 cm renal mass in lower pole of the left kidney with peripheral nodularity and intermediate T2 signal intensity (arrow) concerning for renal cell carcinoma. (B) Biopsy of the lesion demonstrating necrotic tissue and fragments of inflamed kidney parenchyma with areas of fibrin deposition and no definitive evidence of carcinoma. 762", "width": 1160, "height": 530, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80]}, "subfigures": [{"id": "bd0e9bb0-ea2f-410f-91fa-758ac4cd8f82", "label": "a", "points": [[3.7, 3.4], [3.7, 527.5], [555.3, 527.5], [555.3, 3.4]], "color": "yellow"}, {"id": "5a57674c-0eeb-4717-acfa-6d5877f23d14", "label": "b", "points": [[562.7, 5.2], [562.7, 529.3], [1152.7, 529.3], [1152.7, 5.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, 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{"pdf_hash": "7b4891d7f025d4814623627dd4ba3d0b199555bd", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 27-year-old female, parosteal osteosarcoma left distal femur (a) Plain film images of both knees demonstrating bony mass extension from the posterior part of the distal femur. b Axial MRI reveals infiltrative intramedullary lesion and soft tissue component showing heterogenous enhancement with intralesional calcification, (c) sagittal CT scan reveals bony mass involving distal femoral metaphysis from the posterior aspect", "width": 1342, "height": 438, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "bf9c5d52-0f28-49e2-89d3-db944dae6a06", "label": "a", "points": [[24.5, 23], [24.5, 408.8], [505.7, 408.8], [505.7, 23]], "color": 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{"pdf_hash": "11781318965557b6162e6edb756cda571ec6a2b3", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. The location of each amygdala subregion (blue = LB; red = CM; and green = SF). A and B show the amygdala subregions of coronal slices y = 26 and y = 21 in Montreal Neurological Institute (MNI) standard space, respectively. C and D show the amygdala subregions of sagittal slices at x = 225 and x = 27 in MNI standard space, respectively. 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{"pdf_hash": "0901cf5a3032c455f569f4571cfa515f1cbd39d2", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A) Chest X-ray revealed perforation of myocardium by active lead of RV; B) Withdraw spiral tip of first lead and implant a new active lead into septum.", "width": 940, "height": 516, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "6be66a47-70af-4390-9913-97ffb8def62d", "label": "a", "points": [[5.3, 2.7], [5.3, 479.4], [406.2, 479.4], [406.2, 2.7]], "color": "yellow"}, {"id": "cee943ca-62b8-47e6-b5ff-a0ace09cc54a", "label": "b", "points": [[431.4, 2.7], [431.4, 480.9], [900.7, 480.9], [900.7, 2.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Chest", "start": 13, "end": 18, "id": 5}, {"text": "X", "start": 19, "end": 20, "id": 6}, {"text": "-", "start": 20, "end": 21, "id": 7}, {"text": "ray", "start": 21, "end": 24, "id": 8}, {"text": "revealed", "start": 25, "end": 33, "id": 9}, {"text": "perforation", "start": 34, "end": 45, "id": 10}, {"text": "of", "start": 46, "end": 48, "id": 11}, {"text": "myocardium", "start": 49, "end": 59, "id": 12}, {"text": "by", "start": 60, "end": 62, "id": 13}, {"text": "active", "start": 63, "end": 69, "id": 14}, {"text": "lead", "start": 70, "end": 74, "id": 15}, {"text": "of", "start": 75, "end": 77, "id": 16}, {"text": "RV", "start": 78, "end": 80, "id": 17}, {"text": ";", "start": 80, "end": 81, "id": 18}, {"text": "B", "start": 82, "end": 83, "id": 19}, {"text": ")", "start": 83, "end": 84, "id": 20}, {"text": "Withdraw", "start": 85, "end": 93, "id": 21}, {"text": "spiral", "start": 94, "end": 100, "id": 22}, {"text": "tip", "start": 101, "end": 104, "id": 23}, {"text": "of", "start": 105, "end": 107, "id": 24}, {"text": "first", "start": 108, "end": 113, "id": 25}, {"text": "lead", "start": 114, "end": 118, "id": 26}, {"text": "and", "start": 119, "end": 122, "id": 27}, {"text": "implant", "start": 123, "end": 130, "id": 28}, {"text": "a", "start": 131, "end": 132, "id": 29}, {"text": "new", "start": 133, "end": 136, "id": 30}, {"text": "active", "start": 137, "end": 143, "id": 31}, {"text": "lead", "start": 144, "end": 148, "id": 32}, {"text": "into", "start": 149, "end": 153, "id": 33}, {"text": "septum", "start": 154, "end": 160, "id": 34}, {"text": ".", "start": 160, "end": 161, "id": 35}]}
{"pdf_hash": "0f9ee07d73c5de8d41bff4e0248e77cba99151f9", "fig_key": "Figure1", "fig_uri": "13-Figure1-1.png", "text": "Figure 1. Peptidoglycan texture and density is homogenous in cross-sections in cryo-tomograms of both intact cells and purified sacculi (A) Tomographic slice through a live B. subtilis \u0394ponA mutant (a mutant that is thinner than wild-type B. subtilis and thus ammenable to ECT). Scalebar, 200 nm (B) Tomographic slice through an isolated wild-type B. subtilis sacculus. Scalebar, 250 nm (C) Two representative tomographic cross-sections across the wall of isolated B. subtilis sacculi perpendicular to the viewing plane reveal a globally straight sacculus side-wall with local variations in thickness. In both tomographic slices the sacculus interior is to the left. (D) Two representative top-down slices through tomograms parallel to the plane of the sacculus illustrating surface textures (red arrows) previously interpreted to be the surfaces of coiled cables composed of helical coils of peptidoglycan. In both tomography slices the long axis of the cell runs vertically. 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{"pdf_hash": "eb33c50b483bb33a4946f7425a51f967add15e9d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Left, [ 18 F]fluorodeoxyglucose positron emission tomographic scan of 52-year-old patient (patient 5) with alveolar echinococcosis in transaxial section. Patient had explorative surgery and had received albendazole for 2 months before PET. Image shows large focal defect without perilesional FDG uptake (arrow). Right, Corresponding CT scan shows hepatic defect with calcifications (arrows).", "width": 1376, "height": 494, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54], "b": [55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "d6e6c782-2483-4a77-856f-3adce7fd1eed", "label": "a", "points": [[6.9, 11.6], [6.9, 483.3], [661.2, 483.3], [661.2, 11.6]], "color": "yellow"}, {"id": "e7a0939e-234d-4ff1-93b8-2f66fb48469f", "label": "b", "points": [[724.2, 48.5], [724.2, 492], [1372, 492], [1372, 48.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Left", "start": 10, "end": 14, "id": 3}, {"text": ",", "start": 14, "end": 15, "id": 4}, {"text": "[", "start": 16, "end": 17, "id": 5}, {"text": "18", "start": 18, "end": 20, "id": 6}, {"text": "F]fluorodeoxyglucose", "start": 21, "end": 41, "id": 7}, {"text": "positron", "start": 42, "end": 50, "id": 8}, {"text": "emission", "start": 51, "end": 59, "id": 9}, {"text": "tomographic", "start": 60, "end": 71, "id": 10}, {"text": "scan", "start": 72, "end": 76, "id": 11}, {"text": "of", "start": 77, "end": 79, "id": 12}, {"text": "52-year", "start": 80, "end": 87, "id": 13}, {"text": "-", "start": 87, "end": 88, "id": 14}, {"text": "old", "start": 88, "end": 91, "id": 15}, {"text": "patient", "start": 92, "end": 99, "id": 16}, {"text": "(", "start": 100, "end": 101, "id": 17}, {"text": "patient", "start": 101, "end": 108, "id": 18}, {"text": "5", "start": 109, "end": 110, "id": 19}, {"text": ")", "start": 110, "end": 111, "id": 20}, {"text": "with", "start": 112, "end": 116, "id": 21}, {"text": "alveolar", "start": 117, "end": 125, "id": 22}, {"text": "echinococcosis", "start": 126, "end": 140, "id": 23}, {"text": "in", "start": 141, "end": 143, "id": 24}, {"text": "transaxial", "start": 144, "end": 154, "id": 25}, {"text": "section", "start": 155, "end": 162, "id": 26}, {"text": ".", "start": 162, "end": 163, "id": 27}, {"text": "Patient", "start": 164, "end": 171, "id": 28}, {"text": "had", "start": 172, "end": 175, "id": 29}, {"text": "explorative", "start": 176, "end": 187, "id": 30}, {"text": "surgery", "start": 188, "end": 195, "id": 31}, {"text": "and", "start": 196, "end": 199, "id": 32}, {"text": "had", "start": 200, "end": 203, "id": 33}, {"text": "received", "start": 204, "end": 212, "id": 34}, {"text": "albendazole", "start": 213, "end": 224, "id": 35}, {"text": "for", "start": 225, "end": 228, "id": 36}, {"text": "2", "start": 229, "end": 230, "id": 37}, {"text": "months", "start": 231, "end": 237, "id": 38}, {"text": "before", "start": 238, "end": 244, "id": 39}, {"text": "PET", "start": 245, "end": 248, "id": 40}, {"text": ".", "start": 248, "end": 249, "id": 41}, {"text": "Image", "start": 250, "end": 255, "id": 42}, {"text": "shows", "start": 256, "end": 261, "id": 43}, {"text": "large", "start": 262, "end": 267, "id": 44}, {"text": "focal", "start": 268, "end": 273, "id": 45}, {"text": "defect", "start": 274, "end": 280, "id": 46}, {"text": "without", "start": 281, "end": 288, "id": 47}, {"text": "perilesional", "start": 289, "end": 301, "id": 48}, {"text": "FDG", "start": 302, "end": 305, "id": 49}, {"text": "uptake", "start": 306, "end": 312, "id": 50}, {"text": "(", "start": 313, "end": 314, "id": 51}, {"text": "arrow", "start": 314, "end": 319, "id": 52}, {"text": ")", "start": 319, "end": 320, "id": 53}, {"text": ".", "start": 320, "end": 321, "id": 54}, {"text": "Right", "start": 322, "end": 327, "id": 55}, {"text": ",", "start": 327, "end": 328, "id": 56}, {"text": "Corresponding", "start": 329, "end": 342, "id": 57}, {"text": "CT", "start": 343, "end": 345, "id": 58}, {"text": "scan", "start": 346, "end": 350, "id": 59}, {"text": "shows", "start": 351, "end": 356, "id": 60}, {"text": "hepatic", "start": 357, "end": 364, "id": 61}, {"text": "defect", "start": 365, "end": 371, "id": 62}, {"text": "with", "start": 372, "end": 376, "id": 63}, {"text": "calcifications", "start": 377, "end": 391, "id": 64}, {"text": "(", "start": 392, "end": 393, "id": 65}, {"text": "arrows", "start": 393, "end": 399, "id": 66}, {"text": ")", "start": 399, "end": 400, "id": 67}, {"text": ".", "start": 400, "end": 401, "id": 68}]}
{"pdf_hash": "bc1ba0d9ea28e2db5358be4f8f11f97e32918ff7", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. The 3 anatomic sites and regions of interest (ROIs) analyzed. The colored ROIs are superimposed upon high-resolution gradient echo images (axial slices). A: right midforearm: extensor (F-Ext; red) and flexor (F-Flx; purple). B: right transmetatarsal foot: plantar flexors (PFlx; red) and dorsal extensors (D-Ext; purple). C: left midcalf: medial gastrocnemius (Gstrc-M; red) and lateral gastrocnemius (Gstrc-L; pink), soleus (Sol; blue), deep posterior compartment (DPC; yellow), and anterior (AC; light blue) and lateral (LC; green) compartments. 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{"pdf_hash": "f41d3bfbed1157264c9666508de0010aeba42610", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Typical representative axial MR images obtained from WT (A) and H40Y (C) hindlimb muscles and the corresponding automatic segmentation allowing the separation of subcutaneous fat (red), intermuscular fat (blue), skeletal muscle (yellow) and bone/vessels/connective tissues (purple) for WT (B) and H40Y (D) hindlimb. H40Y group showed large muscle atrophy as compared to WT group. doi:10.1371/journal.pone.0061517.g001", "width": 1104, "height": 1214, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 19, 20], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 67, 68], "c": [3, 4, 5, 6, 7, 8, 9, 15, 16, 17, 18, 19, 20], "d": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "a62f85e8-e24e-4276-9b68-44c9a3025498", "label": "a", "points": [[8.8, 32.1], [8.8, 558.8], [535.5, 558.8], [535.5, 32.1]], "color": "yellow"}, {"id": "cbe26751-791c-4d94-a887-78cd32b1b5fc", "label": "b", "points": [[579.1, 28.6], [579.1, 560.5], [1102.3, 560.5], [1102.3, 28.6]], "color": "cyan"}, {"id": "ab774853-41aa-4bed-895b-17adc2d03b8e", "label": "c", "points": [[8.8, 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{"pdf_hash": "21f63f216b5f53c01cbd0b197d2af32f7aa40c7d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (a) CT scan head; (b-d) T1-contrast enhanced MRI showing a left parietooccipital lesion with intraventricular extension. Both solid and cystic components can be appreciated with calcifications on the medial aspect", "width": 592, "height": 516, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9], "b": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26]}, "subfigures": [{"id": "99b804cc-e7bc-4fd8-a24e-faa43391b79b", "label": "a", "points": [[36.5, 5], [36.5, 212], [293.5, 212], [293.5, 5]], "color": "yellow"}, {"id": "53ccc6a7-ef76-46fc-bd0f-d22a73b4a9f7", "label": "b", "points": [[559.5, 1], [559.5, 213], [295.5, 213], [295.5, 1]], "color": "cyan"}, {"id": "263effe0-e001-4077-903e-62fdacfd0dc7", "label": "b", "points": [[289.5, 487], [289.5, 217], [36.5, 217], [36.5, 487]], "color": "magenta"}, {"id": "7f45a40a-8f54-45fd-ad96-67b751dd2545", "label": "b", "points": [[560.5, 217], [560.5, 487], [294.5, 487], [294.5, 217]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "CT", "start": 14, "end": 16, "id": 6}, {"text": "scan", "start": 17, "end": 21, "id": 7}, {"text": "head", "start": 22, "end": 26, "id": 8}, {"text": ";", "start": 26, "end": 27, "id": 9}, {"text": "(", "start": 28, "end": 29, "id": 10}, {"text": "b", "start": 29, "end": 30, "id": 11}, {"text": "-", "start": 30, "end": 31, "id": 12}, {"text": "d", "start": 31, "end": 32, "id": 13}, {"text": ")", "start": 32, "end": 33, "id": 14}, {"text": "T1-contrast", "start": 34, "end": 45, "id": 15}, {"text": "enhanced", "start": 46, "end": 54, "id": 16}, {"text": "MRI", "start": 55, "end": 58, "id": 17}, {"text": "showing", "start": 59, "end": 66, "id": 18}, {"text": "a", "start": 67, "end": 68, "id": 19}, {"text": "left", "start": 69, "end": 73, "id": 20}, {"text": "parietooccipital", "start": 74, "end": 90, "id": 21}, {"text": "lesion", "start": 91, "end": 97, "id": 22}, {"text": "with", "start": 98, "end": 102, "id": 23}, {"text": "intraventricular", "start": 103, "end": 119, "id": 24}, {"text": "extension", "start": 120, "end": 129, "id": 25}, {"text": ".", "start": 129, "end": 130, "id": 26}, {"text": "Both", "start": 131, "end": 135, "id": 27}, {"text": "solid", "start": 136, "end": 141, "id": 28}, {"text": "and", "start": 142, "end": 145, "id": 29}, {"text": "cystic", "start": 146, "end": 152, "id": 30}, {"text": "components", "start": 153, "end": 163, "id": 31}, {"text": "can", "start": 164, "end": 167, "id": 32}, {"text": "be", "start": 168, "end": 170, "id": 33}, {"text": "appreciated", "start": 171, "end": 182, "id": 34}, {"text": "with", "start": 183, "end": 187, "id": 35}, {"text": "calcifications", "start": 188, "end": 202, "id": 36}, {"text": "on", "start": 203, "end": 205, "id": 37}, {"text": "the", "start": 206, "end": 209, "id": 38}, {"text": "medial", "start": 210, "end": 216, "id": 39}, {"text": "aspect", "start": 217, "end": 223, "id": 40}]}
{"pdf_hash": "066625e757bf144e379bdf4d120c892fe85b2162", "fig_key": "Figure4", "fig_uri": "10-Figure4-1.png", "text": "Figure 4. A 23-year-old woman with a giant cell tumor of bone treated with en bloc resection. (a, b) The surgical specimen was dissected to examine its correlation with the coronal image, and pathological samples were taken from this coronal section. (c) Coronal T2-weighted image shows the \u2018\u2018paintbrush borders\u2019\u2019 sign at the upper aspect of the tumor (black arrows). 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{"pdf_hash": "271f9f2b765367515480b5d0765d18b2b111c8c8", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Chest radiography: a) preoperative PA view: mixed hydroaeric image located in the inferior mediastinum; b) postoperative PA view: ascended left hemidiaphragm and normal mediastinum; c) preoperative lateral view: mixed hidroaeric retrocardiac image; d) postoperative lateral view: normal mediastinum.", "width": 866, "height": 662, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "d": [46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "7ec6ebbe-58db-4300-8048-8639b5772501", "label": "a", "points": [[4.8, 1.1], [4.8, 304.8], [423.5, 304.8], [423.5, 1.1]], "color": "yellow"}, {"id": "8a3a18ad-d5af-467d-a079-519fdb83a649", "label": "b", "points": [[446.7, 3.9], [446.7, 308.9], [861.2, 308.9], [861.2, 3.9]], "color": "cyan"}, {"id": "1cb37562-d83d-4e7e-8ab0-e2e455afb78c", "label": "c", "points": [[2.1, 330.8], [2.1, 631.8], [424.8, 631.8], [424.8, 330.8]], "color": "magenta"}, {"id": "7ce1f42b-a73d-4c48-8144-87bab14c6d4f", "label": "d", "points": [[442.6, 328.1], [442.6, 625], [864, 625], [864, 328.1]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Chest", "start": 8, "end": 13, "id": 4}, {"text": "radiography", "start": 14, "end": 25, "id": 5}, {"text": ":", "start": 25, "end": 26, "id": 6}, {"text": "a", "start": 27, "end": 28, "id": 7}, {"text": ")", "start": 28, "end": 29, "id": 8}, {"text": "preoperative", "start": 30, "end": 42, "id": 9}, {"text": "PA", "start": 43, "end": 45, "id": 10}, {"text": "view", "start": 46, "end": 50, "id": 11}, {"text": ":", "start": 50, "end": 51, "id": 12}, {"text": "mixed", "start": 52, "end": 57, "id": 13}, {"text": "hydroaeric", "start": 58, "end": 68, "id": 14}, {"text": "image", "start": 69, "end": 74, "id": 15}, {"text": "located", "start": 75, "end": 82, "id": 16}, {"text": "in", "start": 83, "end": 85, "id": 17}, {"text": "the", "start": 86, "end": 89, "id": 18}, {"text": "inferior", "start": 90, "end": 98, "id": 19}, {"text": "mediastinum", "start": 99, "end": 110, "id": 20}, {"text": ";", "start": 110, "end": 111, "id": 21}, {"text": "b", "start": 112, "end": 113, "id": 22}, {"text": ")", "start": 113, "end": 114, "id": 23}, {"text": "postoperative", "start": 115, "end": 128, "id": 24}, {"text": "PA", "start": 129, "end": 131, "id": 25}, {"text": "view", "start": 132, "end": 136, "id": 26}, {"text": ":", "start": 136, "end": 137, "id": 27}, {"text": "ascended", "start": 138, "end": 146, "id": 28}, {"text": "left", "start": 147, "end": 151, "id": 29}, {"text": "hemidiaphragm", "start": 152, "end": 165, "id": 30}, {"text": "and", "start": 166, "end": 169, "id": 31}, {"text": "normal", "start": 170, "end": 176, "id": 32}, {"text": "mediastinum", "start": 177, "end": 188, "id": 33}, {"text": ";", "start": 188, "end": 189, "id": 34}, {"text": "c", "start": 190, "end": 191, "id": 35}, {"text": ")", "start": 191, "end": 192, "id": 36}, {"text": "preoperative", "start": 193, "end": 205, "id": 37}, {"text": "lateral", "start": 206, "end": 213, "id": 38}, {"text": "view", "start": 214, "end": 218, "id": 39}, {"text": ":", "start": 218, "end": 219, "id": 40}, {"text": "mixed", "start": 220, "end": 225, "id": 41}, {"text": "hidroaeric", "start": 226, "end": 236, "id": 42}, {"text": "retrocardiac", "start": 237, "end": 249, "id": 43}, {"text": "image", "start": 250, "end": 255, "id": 44}, {"text": ";", "start": 255, "end": 256, "id": 45}, {"text": "d", "start": 257, "end": 258, "id": 46}, {"text": ")", "start": 258, "end": 259, "id": 47}, {"text": "postoperative", "start": 260, "end": 273, "id": 48}, {"text": "lateral", "start": 274, "end": 281, "id": 49}, {"text": "view", "start": 282, "end": 286, "id": 50}, {"text": ":", "start": 286, "end": 287, "id": 51}, {"text": "normal", "start": 288, "end": 294, "id": 52}, {"text": "mediastinum", "start": 295, "end": 306, "id": 53}, {"text": ".", "start": 306, "end": 307, "id": 54}]}
{"pdf_hash": "e6320f0c8d6281791b5c71a958ca6e11bfe99e48", "fig_key": "Figure6", "fig_uri": "10-Figure6-1.png", "text": "Figure 6. Electron micrographs illustrating the process of cell death observed in oocysts of the DRep and DNDRep mutants. A. Low power of a DNDRep oocyst with a degenerating, undifferentiated central cytoplasmic mass. Bar is 10 mm. B. Detail from the degeneration of a DNDRep oocyst similar to that in A showing a dilated nuclear membrane containing a number of nuclei (N) exhibiting peripheral chromatin condensation. Bar is 100 nm. C. Low power of a DRep oocyst in which sporozoite formation had occurred but now exhibited features of cell degeneration. Bar is 10 mm. D. Detail of the nuclei observed in an intact DNDRep oocyst showing the absence of any peripheral nuclear condensation. Bar is 100 nm. E. Longitudinal section through a sporozoite showing the nucleus with peripheral chromatin condensation and dilatation of the nuclear membranes. N -nucleus. Bar is 500 nm. F. Low power of a DRep oocyst in which there is a cross section of a central mass of degenerating sporozoites (S). Bar is 10 mm. G. Histogram comparing the relative number of immature mature and degenerate oocysts at two time points (12-14 days and 18-21 days) for WT, DRep and DNDRep oocysts. 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{"pdf_hash": "bde90e3e9b0fa28a131fffa809ca49766e1e22b6", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5. Representative HRCT findings in a 37-year-old woman (case 5). (A) HRCT scan obtained 2 weeks after paraquat ingestion shows diffuse groundglass opacity in the left lung and focal ground-glass opacity in the right lung. (B) HRCT scan obtained 20 months after paraquat ingestion shows subpleural lines in the posterior portion of the left upper lobe, but bilateral consolidation is not evident.", "width": 932, "height": 690, "subcaptions": {"a": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77]}, "subfigures": [{"id": "9cad3fe4-22b0-4085-b950-5ca947bfd63d", "label": "a", "points": [[5.2, -0.9], [5.2, 296.5], [452.8, 296.5], [452.8, -0.9]], "color": "yellow"}, {"id": "17729ce7-7156-49a9-a118-f0fc53a72850", "label": "b", "points": [[474.9, -0.9], [474.9, 298], [923.9, 298], [923.9, -0.9]], "color": "cyan"}, {"id": "1cc9676b-0c45-480f-8b6b-4b9f4efd0260", "label": "a", "points": [[2.3, 393.7], [2.3, 688.2], [449.8, 688.2], [449.8, 393.7]], "color": "magenta"}, {"id": "3002bfaa-a040-482d-8807-70f9163a8395", "label": "b", "points": [[483.7, 393.7], [483.7, 682.3], [928.3, 682.3], [928.3, 393.7]], "color": "springgreen"}], "tokens": 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{"pdf_hash": "5d4ecce29b497679cb7fce7ca22baec398a62d54", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Spinal computed tomography of the patient. (A) Sagittal image and (B) axial image at the L4-5 intervertebral disc level. L4, 4th lumbar vertebra; L5, 5th lumbar vertebra.", "width": 1004, "height": 474, "subcaptions": {"a": [11, 12, 13, 14, 15, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "7aee73b4-3518-40e9-888c-0ea599c70973", "label": "a", "points": [[8.7, 11.1], [8.7, 467.9], [475, 467.9], [475, 11.1]], "color": "yellow"}, {"id": "c9162ccf-6d92-4cd6-b23e-9ef5a0ac4d7b", "label": "b", "points": [[498.8, 4.8], [498.8, 466.3], [969.9, 466.3], [969.9, 4.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Spinal", "start": 8, "end": 14, "id": 4}, {"text": "computed", "start": 15, "end": 23, "id": 5}, {"text": "tomography", "start": 24, "end": 34, "id": 6}, {"text": "of", "start": 35, "end": 37, "id": 7}, {"text": "the", "start": 38, "end": 41, "id": 8}, {"text": "patient", "start": 42, "end": 49, "id": 9}, {"text": ".", "start": 49, "end": 50, "id": 10}, {"text": "(", "start": 51, "end": 52, "id": 11}, {"text": "A", "start": 52, "end": 53, "id": 12}, {"text": ")", "start": 53, "end": 54, "id": 13}, {"text": "Sagittal", "start": 55, "end": 63, "id": 14}, {"text": "image", "start": 64, "end": 69, "id": 15}, {"text": "and", "start": 70, "end": 73, "id": 16}, {"text": "(", "start": 74, "end": 75, "id": 17}, {"text": "B", "start": 75, "end": 76, "id": 18}, {"text": ")", "start": 76, "end": 77, "id": 19}, {"text": "axial", "start": 78, "end": 83, "id": 20}, {"text": "image", "start": 84, "end": 89, "id": 21}, {"text": "at", "start": 90, "end": 92, "id": 22}, {"text": "the", "start": 93, "end": 96, "id": 23}, {"text": "L4", "start": 97, "end": 99, "id": 24}, {"text": "-", "start": 99, "end": 100, "id": 25}, {"text": "5", "start": 100, "end": 101, "id": 26}, {"text": "intervertebral", "start": 102, "end": 116, "id": 27}, {"text": "disc", "start": 117, "end": 121, "id": 28}, {"text": "level", "start": 122, "end": 127, "id": 29}, {"text": ".", "start": 127, "end": 128, "id": 30}, {"text": "L4", "start": 129, "end": 131, "id": 31}, {"text": ",", "start": 131, "end": 132, "id": 32}, {"text": "4th", "start": 133, "end": 136, "id": 33}, {"text": "lumbar", "start": 137, "end": 143, "id": 34}, {"text": "vertebra", "start": 144, "end": 152, "id": 35}, {"text": ";", "start": 152, "end": 153, "id": 36}, {"text": "L5", "start": 154, "end": 156, "id": 37}, {"text": ",", "start": 156, "end": 157, "id": 38}, {"text": "5th", "start": 158, "end": 161, "id": 39}, {"text": "lumbar", "start": 162, "end": 168, "id": 40}, {"text": "vertebra", "start": 169, "end": 177, "id": 41}, {"text": ".", "start": 177, "end": 178, "id": 42}]}
{"pdf_hash": "136d02a3d0ec26275b9fd1d4eac267f1bfe41050", "fig_key": "Figure2", "fig_uri": "1-Figure2-1.png", "text": "Figure 2 Arterial phase CT of a patient with paraoesophageal omental hernia in (A) axial, (B) sagittal and (C) coronal planes.", "width": 1116, "height": 400, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 27, 28], "b": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 18, 19, 20, 21, 27, 28], "c": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "c8968e7f-4f5f-44f5-81a9-43bb101b5c12", "label": "a", "points": [[21.5, 4.1], [21.5, 381.4], [479.9, 381.4], [479.9, 4.1]], "color": "yellow"}, {"id": "297b92ad-f5e4-429b-8d4b-7bd9fa1af593", "label": "b", "points": [[495.7, 2.4], [495.7, 370.8], [760.2, 370.8], [760.2, 2.4]], "color": "cyan"}, {"id": "975791e5-a3a0-46db-a49d-0d10dd9152e7", "label": "c", "points": [[776.1, 7.6], [776.1, 369.1], [1114.6, 369.1], [1114.6, 7.6]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Arterial", "start": 9, "end": 17, "id": 2}, {"text": "phase", "start": 18, "end": 23, "id": 3}, {"text": "CT", "start": 24, "end": 26, "id": 4}, {"text": "of", "start": 27, "end": 29, "id": 5}, {"text": "a", "start": 30, "end": 31, "id": 6}, {"text": "patient", "start": 32, "end": 39, "id": 7}, {"text": "with", "start": 40, "end": 44, "id": 8}, {"text": "paraoesophageal", "start": 45, "end": 60, "id": 9}, {"text": "omental", "start": 61, "end": 68, "id": 10}, {"text": "hernia", "start": 69, "end": 75, "id": 11}, {"text": "in", "start": 76, "end": 78, "id": 12}, {"text": "(", "start": 79, "end": 80, "id": 13}, {"text": "A", "start": 80, "end": 81, "id": 14}, {"text": ")", "start": 81, "end": 82, "id": 15}, {"text": "axial", "start": 83, "end": 88, "id": 16}, {"text": ",", "start": 88, "end": 89, "id": 17}, {"text": "(", "start": 90, "end": 91, "id": 18}, {"text": "B", "start": 91, "end": 92, "id": 19}, {"text": ")", "start": 92, "end": 93, "id": 20}, {"text": "sagittal", "start": 94, "end": 102, "id": 21}, {"text": "and", "start": 103, "end": 106, "id": 22}, {"text": "(", "start": 107, "end": 108, "id": 23}, {"text": "C", "start": 108, "end": 109, "id": 24}, {"text": ")", "start": 109, "end": 110, "id": 25}, {"text": "coronal", "start": 111, "end": 118, "id": 26}, {"text": "planes", "start": 119, "end": 125, "id": 27}, {"text": ".", "start": 125, "end": 126, "id": 28}]}
{"pdf_hash": "9dd5d2fced54396e5d34589aad480a6065a21299", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Sagittal cone-beam computed tomography sections. The level of the occlusal plane of the maxillary third molar is classified as high when the midpoint of the maxillary third molar (white dot) is at or above the cementoenamel junction of the maxillary second molar (gray line) (A), as medium when the midpoint of the maxillary third molar (white dot) is between the occlusal plane of the maxillary second molar (white line) and the cementoenamel junction (gray line) (B), and as low when the midpoint of the maxillary third molar (white dot) is at or below the occlusal plane of the maxillary second molar (white line) (C).", "width": 1338, "height": 492, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 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{"pdf_hash": "d24980f9de8c7460f2b11106307eb6d442da90a2", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Thorax CT demonstrated bilateral widespread infiltration in the lung extending to the apexes, which is not accompanied by cardiomegaly. a: Thorax CT apical level of lung. b: Thorax CT middle cardiac level.", "width": 654, "height": 896, "subcaptions": {"a": [25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "b5399559-0d3b-4cf9-9f71-8dfacf634fd9", "label": "a", "points": [[26.4, 16.4], [26.4, 420.3], [648.3, 420.3], [648.3, 16.4]], "color": "yellow"}, {"id": "c4cf2d60-d1cf-4286-ab12-dfa5ab800f46", "label": "b", "points": [[27.4, 466.3], [27.4, 894], [650.4, 894], [650.4, 466.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Thorax", "start": 8, "end": 14, "id": 4}, {"text": "CT", "start": 15, "end": 17, "id": 5}, {"text": "demonstrated", "start": 18, "end": 30, "id": 6}, {"text": "bilateral", "start": 31, "end": 40, "id": 7}, {"text": "widespread", "start": 41, "end": 51, "id": 8}, {"text": "infiltration", "start": 52, "end": 64, "id": 9}, {"text": "in", "start": 65, "end": 67, "id": 10}, {"text": "the", "start": 68, "end": 71, "id": 11}, {"text": "lung", "start": 72, "end": 76, "id": 12}, {"text": "extending", "start": 77, "end": 86, "id": 13}, {"text": "to", "start": 87, "end": 89, "id": 14}, {"text": "the", "start": 90, "end": 93, "id": 15}, {"text": "apexes", "start": 94, "end": 100, "id": 16}, {"text": ",", "start": 100, "end": 101, "id": 17}, {"text": "which", "start": 102, "end": 107, "id": 18}, {"text": "is", "start": 108, "end": 110, "id": 19}, {"text": "not", "start": 111, "end": 114, "id": 20}, {"text": "accompanied", "start": 115, "end": 126, "id": 21}, {"text": "by", "start": 127, "end": 129, "id": 22}, {"text": "cardiomegaly", "start": 130, "end": 142, "id": 23}, {"text": ".", "start": 142, "end": 143, "id": 24}, {"text": "a", "start": 144, "end": 145, "id": 25}, {"text": ":", "start": 145, "end": 146, "id": 26}, {"text": "Thorax", "start": 147, "end": 153, "id": 27}, {"text": "CT", "start": 154, "end": 156, "id": 28}, {"text": "apical", "start": 157, "end": 163, "id": 29}, {"text": "level", "start": 164, "end": 169, "id": 30}, {"text": "of", "start": 170, "end": 172, "id": 31}, {"text": "lung", "start": 173, "end": 177, "id": 32}, {"text": ".", "start": 177, "end": 178, "id": 33}, {"text": "b", "start": 179, "end": 180, "id": 34}, {"text": ":", "start": 180, "end": 181, "id": 35}, {"text": "Thorax", "start": 182, "end": 188, "id": 36}, {"text": "CT", "start": 189, "end": 191, "id": 37}, {"text": "middle", "start": 192, "end": 198, "id": 38}, {"text": "cardiac", "start": 199, "end": 206, "id": 39}, {"text": "level", "start": 207, "end": 212, "id": 40}, {"text": ".", "start": 212, "end": 213, "id": 41}]}
{"pdf_hash": "f75e066e4a395627b570510921d758990da81631", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3: Resolution of infectious scleritis lesion after a 3-week course of fortified tobramycin and fortified vancomycin, and moxifloxacin 0.05%, (a) External photograph, (b) Optical coherence tomography image showing resolution of serous retinal detachment", "width": 540, "height": 510, "subcaptions": {"a": [24, 25, 26, 27, 28], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "04def0e6-aaf3-4fbf-bd5f-be39b8c22d03", "label": "a", "points": [[33, -0.2], [33, 296.8], [513, 296.8], [513, -0.2]], "color": "yellow"}, {"id": "8589b82c-7287-4763-b254-e49c8071a507", "label": "b", "points": [[32, 302.8], [32, 483.8], [515, 483.8], [515, 302.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Resolution", "start": 10, "end": 20, "id": 3}, {"text": "of", "start": 21, "end": 23, "id": 4}, {"text": "infectious", "start": 24, "end": 34, "id": 5}, {"text": "scleritis", "start": 35, "end": 44, "id": 6}, {"text": "lesion", "start": 45, "end": 51, "id": 7}, {"text": "after", "start": 52, "end": 57, "id": 8}, {"text": "a", "start": 58, "end": 59, "id": 9}, {"text": "3-week", "start": 60, "end": 66, "id": 10}, {"text": "course", "start": 67, "end": 73, "id": 11}, {"text": "of", "start": 74, "end": 76, "id": 12}, {"text": "fortified", "start": 77, "end": 86, "id": 13}, {"text": "tobramycin", "start": 87, "end": 97, "id": 14}, {"text": "and", "start": 98, "end": 101, "id": 15}, {"text": "fortified", "start": 102, "end": 111, "id": 16}, {"text": "vancomycin", "start": 112, "end": 122, "id": 17}, {"text": ",", "start": 122, "end": 123, "id": 18}, {"text": "and", "start": 124, "end": 127, "id": 19}, {"text": "moxifloxacin", "start": 128, "end": 140, "id": 20}, {"text": "0.05", "start": 141, "end": 145, "id": 21}, {"text": "%", "start": 145, "end": 146, "id": 22}, {"text": ",", "start": 146, "end": 147, "id": 23}, {"text": "(", "start": 148, "end": 149, "id": 24}, {"text": "a", "start": 149, "end": 150, "id": 25}, {"text": ")", "start": 150, "end": 151, "id": 26}, {"text": "External", "start": 152, "end": 160, "id": 27}, {"text": "photograph", "start": 161, "end": 171, "id": 28}, {"text": ",", "start": 171, "end": 172, "id": 29}, {"text": "(", "start": 173, "end": 174, "id": 30}, {"text": "b", "start": 174, "end": 175, "id": 31}, {"text": ")", "start": 175, "end": 176, "id": 32}, {"text": "Optical", "start": 177, "end": 184, "id": 33}, {"text": "coherence", "start": 185, "end": 194, "id": 34}, {"text": "tomography", "start": 195, "end": 205, "id": 35}, {"text": "image", "start": 206, "end": 211, "id": 36}, {"text": "showing", "start": 212, "end": 219, "id": 37}, {"text": "resolution", "start": 220, "end": 230, "id": 38}, {"text": "of", "start": 231, "end": 233, "id": 39}, {"text": "serous", "start": 234, "end": 240, "id": 40}, {"text": "retinal", "start": 241, "end": 248, "id": 41}, {"text": "detachment", "start": 249, "end": 259, "id": 42}]}
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{"pdf_hash": "17f5ec1de3f69d037e78e6314ea0150b5348919c", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 (Continued) Case 2. G: Axial t 2 * MR image at the C4 level 24 days after the onset showing a low intensity lesion indicating hemorrhage. H: operative photograph showing intradural draining veins (white arrow) ascending along the right C4 ventral nerve root and the radiculomedullary artery (asterisk) connecting with the anterior spinal artery. I: post-operative angiography showing disappearance of the perimedullary venous drainage and faint residual fistula of the epidural space. J: t 2 -weighted MR imaging 1 month after the operation showing marked decrease of the spinal cord edema. 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{"pdf_hash": "ad871318fa531e6cf3dcef95999f3b4763fefdff", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Samples studied in this work. (a) \u2018Zebra rock\u2019 sample used for the computed tomography study. Crystal pseudomorphs are located in the bottom brown layer. (b) Thin section of the rock used for the microscopy and EDX studies. Note the pseudohexagonal outline of the crystals. 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{"pdf_hash": "e19831c465920e166a94a84d1bc0b5624eaf89d3", "fig_key": "Figure2", "fig_uri": "9-Figure2-1.png", "text": "Fig 2. 33-year-old woman with invasive ductal carcinoma in the left breast. Contrast-enhanced T1-weighted axial image (A), readout-segmented echo-planar DWI image (B), and ADC map (C). (A) Round", "width": 822, "height": 1722, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "c": [39, 40, 41, 42, 43]}, "subfigures": [{"id": "a5ba0be2-7704-47ec-9923-a32307faf2f7", "label": "a", "points": [[6.7, 3], [6.7, 532.9], [796.2, 532.9], [796.2, 3]], "color": "yellow"}, {"id": "9ea1aaf8-aeb3-40bc-9701-5fba6acb9f2e", "label": "b", "points": [[17.1, 543.7], [17.1, 1104.7], [789.8, 1104.7], [789.8, 543.7]], "color": "cyan"}, {"id": "ef4b3164-4a24-4766-8192-f5db50419a9b", "label": "c", "points": [[6.7, 1125], [6.7, 1684.7], [791.1, 1684.7], [791.1, 1125]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "33-year", "start": 7, "end": 14, "id": 3}, {"text": "-", "start": 14, "end": 15, "id": 4}, {"text": "old", "start": 15, "end": 18, "id": 5}, {"text": "woman", "start": 19, "end": 24, "id": 6}, {"text": "with", "start": 25, "end": 29, "id": 7}, {"text": "invasive", "start": 30, "end": 38, "id": 8}, {"text": "ductal", "start": 39, "end": 45, "id": 9}, {"text": "carcinoma", "start": 46, "end": 55, "id": 10}, {"text": "in", "start": 56, "end": 58, "id": 11}, {"text": "the", "start": 59, "end": 62, "id": 12}, {"text": "left", "start": 63, "end": 67, "id": 13}, {"text": "breast", "start": 68, "end": 74, "id": 14}, {"text": ".", "start": 74, "end": 75, "id": 15}, {"text": "Contrast", "start": 76, "end": 84, "id": 16}, {"text": "-", "start": 84, "end": 85, "id": 17}, {"text": "enhanced", "start": 85, "end": 93, "id": 18}, {"text": "T1-weighted", "start": 94, "end": 105, "id": 19}, {"text": "axial", "start": 106, "end": 111, "id": 20}, {"text": "image", "start": 112, "end": 117, "id": 21}, {"text": "(", "start": 118, "end": 119, "id": 22}, {"text": "A", "start": 119, "end": 120, "id": 23}, {"text": ")", "start": 120, "end": 121, "id": 24}, {"text": ",", "start": 121, "end": 122, "id": 25}, {"text": "readout", "start": 123, "end": 130, "id": 26}, {"text": "-", "start": 130, "end": 131, "id": 27}, {"text": "segmented", "start": 131, "end": 140, "id": 28}, {"text": "echo", "start": 141, "end": 145, "id": 29}, {"text": "-", "start": 145, "end": 146, "id": 30}, {"text": "planar", "start": 146, "end": 152, "id": 31}, {"text": "DWI", "start": 153, "end": 156, "id": 32}, {"text": "image", "start": 157, "end": 162, "id": 33}, {"text": "(", "start": 163, "end": 164, "id": 34}, {"text": "B", "start": 164, "end": 165, "id": 35}, {"text": ")", "start": 165, "end": 166, "id": 36}, {"text": ",", "start": 166, "end": 167, "id": 37}, {"text": "and", "start": 168, "end": 171, "id": 38}, {"text": "ADC", "start": 172, "end": 175, "id": 39}, {"text": "map", "start": 176, "end": 179, "id": 40}, {"text": "(", "start": 180, "end": 181, "id": 41}, {"text": "C", "start": 181, "end": 182, "id": 42}, {"text": ")", "start": 182, "end": 183, "id": 43}, {"text": ".", "start": 183, "end": 184, "id": 44}, {"text": "(", "start": 185, "end": 186, "id": 45}, {"text": "A", "start": 186, "end": 187, "id": 46}, {"text": ")", "start": 187, "end": 188, "id": 47}, {"text": "Round", "start": 189, "end": 194, "id": 48}]}
{"pdf_hash": "dd4cbf83217b1043b613e7d88057b03050a03c92", "fig_key": "Figure1", "fig_uri": "7-Figure1-1.png", "text": "Fig 1. Feasibility of contrast enhanced CT via i.o. access with very good enhancement of the major thoracic vessels (A) and parenchymatous upper abdominal organs (B).", "width": 980, "height": 1782, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 25, 26, 27, 28, 29, 30, 31, 32]}, "subfigures": [{"id": "b237a2e6-20bb-413a-97ed-ef2d388c21a6", "label": "a", "points": [[15.5, 60.1], [15.5, 855.8], [945.9, 855.8], [945.9, 60.1]], "color": "yellow"}, {"id": "d8f4c8f5-b516-4605-876e-d795d1e7b697", "label": "b", "points": [[15.5, 950.3], [15.5, 1747.5], [947.5, 1747.5], [947.5, 950.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "1", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Feasibility", "start": 7, "end": 18, "id": 3}, {"text": "of", "start": 19, "end": 21, "id": 4}, {"text": "contrast", "start": 22, "end": 30, "id": 5}, {"text": "enhanced", "start": 31, "end": 39, "id": 6}, {"text": "CT", "start": 40, "end": 42, "id": 7}, {"text": "via", "start": 43, "end": 46, "id": 8}, {"text": "i.o", "start": 47, "end": 50, "id": 9}, {"text": ".", "start": 50, "end": 51, "id": 10}, {"text": "access", "start": 52, "end": 58, "id": 11}, {"text": "with", "start": 59, "end": 63, "id": 12}, {"text": "very", "start": 64, "end": 68, "id": 13}, {"text": "good", "start": 69, "end": 73, "id": 14}, {"text": "enhancement", "start": 74, "end": 85, "id": 15}, {"text": "of", "start": 86, "end": 88, "id": 16}, {"text": "the", "start": 89, "end": 92, "id": 17}, {"text": "major", "start": 93, "end": 98, "id": 18}, {"text": "thoracic", "start": 99, "end": 107, "id": 19}, {"text": "vessels", "start": 108, "end": 115, "id": 20}, {"text": "(", "start": 116, "end": 117, "id": 21}, {"text": "A", "start": 117, "end": 118, "id": 22}, {"text": ")", "start": 118, "end": 119, "id": 23}, {"text": "and", "start": 120, "end": 123, "id": 24}, {"text": "parenchymatous", "start": 124, "end": 138, "id": 25}, {"text": "upper", "start": 139, "end": 144, "id": 26}, {"text": "abdominal", "start": 145, "end": 154, "id": 27}, {"text": "organs", "start": 155, "end": 161, "id": 28}, {"text": "(", "start": 162, "end": 163, "id": 29}, {"text": "B", "start": 163, "end": 164, "id": 30}, {"text": ")", "start": 164, "end": 165, "id": 31}, {"text": ".", "start": 165, "end": 166, "id": 32}]}
{"pdf_hash": "147cd60fdd957efe1f6e62d8167efb2798c375c1", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Abdominal CT scan of patient No. 6M, showing a right mesenterial metastasis: a, before treatment and b, after five cycles of IL-2 and INF alfa-2a.", "width": 668, "height": 664, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "739293e9-8160-476e-858f-70aede9af41b", "label": "a", "points": [[10.1, 85.3], [10.1, 660.4], [667.5, 660.4], [667.5, 85.3]], "color": "yellow"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Abdominal", "start": 9, "end": 18, "id": 2}, {"text": "CT", "start": 19, "end": 21, "id": 3}, {"text": "scan", "start": 22, "end": 26, "id": 4}, {"text": "of", "start": 27, "end": 29, "id": 5}, {"text": "patient", "start": 30, "end": 37, "id": 6}, {"text": "No", "start": 38, "end": 40, "id": 7}, {"text": ".", "start": 40, "end": 41, "id": 8}, {"text": "6", "start": 42, "end": 43, "id": 9}, {"text": "M", "start": 43, "end": 44, "id": 10}, {"text": ",", "start": 44, "end": 45, "id": 11}, {"text": "showing", "start": 46, "end": 53, "id": 12}, {"text": "a", "start": 54, "end": 55, "id": 13}, {"text": "right", "start": 56, "end": 61, "id": 14}, {"text": "mesenterial", "start": 62, "end": 73, "id": 15}, {"text": "metastasis", "start": 74, "end": 84, "id": 16}, {"text": ":", "start": 84, "end": 85, "id": 17}, {"text": "a", "start": 86, "end": 87, "id": 18}, {"text": ",", "start": 87, "end": 88, "id": 19}, {"text": "before", "start": 89, "end": 95, "id": 20}, {"text": "treatment", "start": 96, "end": 105, "id": 21}, {"text": "and", "start": 106, "end": 109, "id": 22}, {"text": "b", "start": 110, "end": 111, "id": 23}, {"text": ",", "start": 111, "end": 112, "id": 24}, {"text": "after", "start": 113, "end": 118, "id": 25}, {"text": "five", "start": 119, "end": 123, "id": 26}, {"text": "cycles", "start": 124, "end": 130, "id": 27}, {"text": "of", "start": 131, "end": 133, "id": 28}, {"text": "IL-2", "start": 134, "end": 138, "id": 29}, {"text": "and", "start": 139, "end": 142, "id": 30}, {"text": "INF", "start": 143, "end": 146, "id": 31}, {"text": "alfa-2a", "start": 147, "end": 154, "id": 32}, {"text": ".", "start": 154, "end": 155, "id": 33}]}
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{"pdf_hash": "7ad2bc3afc70323dcca2e066ed5739f880dc69a8", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. CT images of the abdomen. (A) The CT revealed the right hydronephrosis and (B) a thickening of the right distal ureter (illustrated by the white arrow). CT, computed tomography.", "width": 570, "height": 894, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [12, 13, 14, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36]}, "subfigures": [{"id": "c2773e52-4684-46af-99ed-ccf5c310791d", "label": "a", "points": [[25.4, 3.1], [25.4, 406.1], [534.4, 406.1], [534.4, 3.1]], "color": "yellow"}, {"id": "87763578-a97a-4aef-a07b-00b18ba8c115", "label": "b", "points": [[25.4, 449.1], [25.4, 855.1], [532.4, 855.1], [532.4, 449.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "images", "start": 13, "end": 19, "id": 4}, {"text": "of", "start": 20, "end": 22, "id": 5}, {"text": "the", "start": 23, "end": 26, "id": 6}, {"text": "abdomen", "start": 27, "end": 34, "id": 7}, {"text": ".", "start": 34, "end": 35, "id": 8}, {"text": "(", "start": 36, "end": 37, "id": 9}, {"text": "A", "start": 37, "end": 38, "id": 10}, {"text": ")", "start": 38, "end": 39, "id": 11}, {"text": "The", "start": 40, "end": 43, "id": 12}, {"text": "CT", "start": 44, "end": 46, "id": 13}, {"text": "revealed", "start": 47, "end": 55, "id": 14}, {"text": "the", "start": 56, "end": 59, "id": 15}, {"text": "right", "start": 60, "end": 65, "id": 16}, {"text": "hydronephrosis", "start": 66, "end": 80, "id": 17}, {"text": "and", "start": 81, "end": 84, "id": 18}, {"text": "(", "start": 85, "end": 86, "id": 19}, {"text": "B", "start": 86, "end": 87, "id": 20}, {"text": ")", "start": 87, "end": 88, "id": 21}, {"text": "a", "start": 89, "end": 90, "id": 22}, {"text": "thickening", "start": 91, "end": 101, "id": 23}, {"text": "of", "start": 102, "end": 104, "id": 24}, {"text": "the", "start": 105, "end": 108, "id": 25}, {"text": "right", "start": 109, "end": 114, "id": 26}, {"text": "distal", "start": 115, "end": 121, "id": 27}, {"text": "ureter", "start": 122, "end": 128, "id": 28}, {"text": "(", "start": 129, "end": 130, "id": 29}, {"text": "illustrated", "start": 130, "end": 141, "id": 30}, {"text": "by", "start": 142, "end": 144, "id": 31}, {"text": "the", "start": 145, "end": 148, "id": 32}, {"text": "white", "start": 149, "end": 154, "id": 33}, {"text": "arrow", "start": 155, "end": 160, "id": 34}, {"text": ")", "start": 160, "end": 161, "id": 35}, {"text": ".", "start": 161, "end": 162, "id": 36}, {"text": "CT", "start": 163, "end": 165, "id": 37}, {"text": ",", "start": 165, "end": 166, "id": 38}, {"text": "computed", "start": 167, "end": 175, "id": 39}, {"text": "tomography", "start": 176, "end": 186, "id": 40}, {"text": ".", "start": 186, "end": 187, "id": 41}]}
{"pdf_hash": "b06d06358577ab94c53fea5364bbdd0e01aad8f7", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2 A photomicrograph of a (a, b) coronal section taken through the orbitofrontal cortex (OFC) from a representative OFC-lesioned rat (a, arrowheads indicate lesion location) and sham-operated rat (b), and (c) a coronal section taken through the striatum of a representative cannulaimplanted rat showing the cannula tract (Experiment 2).", "width": 910, "height": 344, "subcaptions": {"a": [2, 3, 4, 5, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [2, 3, 4, 5, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 37, 38, 39, 40, 41, 42, 43], "c": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "d9d025cf-c3c9-4dda-b195-11ffb0874a70", "label": "a", "points": [[2.9, 1.4], [2.9, 322], [207, 322], [207, 1.4]], "color": "yellow"}, {"id": 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{"pdf_hash": "8bfbaf08f105fe21f30ca63c987a99b0b8de6748", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: Normal ulnar collateral ligament of the first metacarpal phalangeal joint in the right thumb. (a) Schematic drawing of the UCL in the first MCPJ shows the UCL (arrow) attaches to the ulnar aspect of the dorsal tubercle of the first metacarpal and inserts into the base of the proximal phalanx. The adductor aponeurosis (dotted arrow) lies superficial to the UCL. (b) A coronal image of the right thumb of a 40\u2011year\u2011old cadaver specimen. (c and d) T1 and PD FS coronal images of the right thumb in a 40\u2011year\u2011old cadaver specimen showed normal ulnar collateral ligament and adductor aponeurosis. 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{"pdf_hash": "41b290d8f9725117fe86212f47632bdad87cc10c", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. (A) 18 F-FDG-PET scan of patient UPN 1 at diagnosis of extramedullary AML. (B) Coronal and transversal 18 F-FDG-PET/CT fusion images of the EM in the left mammary gland at diagnosis. (C) 18 F-FDG-PET scan of the same patient after salvage chemotherapy (note: higher bone marrow 18 F-FDG uptake due to higher bone marrow activity). 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{"pdf_hash": "0eecbf2d1edfa0a58d2c5a24040e5560bce45e5f", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Source peaks for activity reconstruction. Left: Sources for which MEG field strength amplitude across all trialswas different from zero at an uncorrected significance threshold of p b 0.05 (shown with infinite search depth). Right: Source peaks at which activity was reconstructed and analyzed. Activity was reconstructed at a source peak if the field strength amplitude across all trials was different from zero at a significance threshold p b 0.05 (uncorrected for multiple comparisons) with a minimum peak-to-peak distance of 3 mm. This liberal criterion for source activation was selected to ensure a large number of sources (109) for subsequent multivariate analyses on which conclusions are based. Sources were grouped according to overall cortical position: Green = occipital lobe, cyan = temporal lobe, hot red/yellow = parietal lobe, blue = precentral/postcentral gyri, red = prefrontal areas. 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{"pdf_hash": "ed9a43ac0d00815569d96ec15e71106bd4ab9f96", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "FIG. 2. Scan of the logic area of an integrated circuit. (a) AFM topography and (b) tunneling current images. Metallic pins are visible in both images (bright dots); however, additionally, some features located on the nonconductive substrate are visible only in the AFM topography scan. 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{"pdf_hash": "fe366facc4eb38621c523712455496c6b9e89885", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 Three-dimensional multiplanar ultrasound image depicting the outlining of cyst content (a) for histogram calculation of the mean gray (MG) value (b).", "width": 660, "height": 1090, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "43fbd9fe-44ed-49dd-b6d3-aa976dfd5ae7", "label": "a", "points": [[-0.2, 32.1], [-0.2, 543], [657.7, 543], [657.7, 32.1]], "color": "yellow"}, {"id": "5294d1a4-e32d-4bf3-aacb-f9edacfb44b4", "label": "b", "points": [[-0.2, 578.5], [-0.2, 1086.2], [658.7, 1086.2], [658.7, 578.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Three", "start": 9, "end": 14, "id": 2}, {"text": "-", "start": 14, "end": 15, "id": 3}, {"text": "dimensional", "start": 15, "end": 26, "id": 4}, {"text": "multiplanar", "start": 27, "end": 38, "id": 5}, {"text": "ultrasound", "start": 39, "end": 49, "id": 6}, {"text": "image", "start": 50, "end": 55, "id": 7}, {"text": "depicting", "start": 56, "end": 65, "id": 8}, {"text": "the", "start": 66, "end": 69, "id": 9}, {"text": "outlining", "start": 70, "end": 79, "id": 10}, {"text": "of", "start": 80, "end": 82, "id": 11}, {"text": "cyst", "start": 83, "end": 87, "id": 12}, {"text": "content", "start": 88, "end": 95, "id": 13}, {"text": "(", "start": 96, "end": 97, "id": 14}, {"text": "a", "start": 97, "end": 98, "id": 15}, {"text": ")", "start": 98, "end": 99, "id": 16}, {"text": "for", "start": 100, "end": 103, "id": 17}, {"text": "histogram", "start": 104, "end": 113, "id": 18}, {"text": "calculation", "start": 114, "end": 125, "id": 19}, {"text": "of", "start": 126, "end": 128, "id": 20}, {"text": "the", "start": 129, "end": 132, "id": 21}, {"text": "mean", "start": 133, "end": 137, "id": 22}, {"text": "gray", "start": 138, "end": 142, "id": 23}, {"text": "(", "start": 143, "end": 144, "id": 24}, {"text": "MG", "start": 144, "end": 146, "id": 25}, {"text": ")", "start": 146, "end": 147, "id": 26}, {"text": "value", "start": 148, "end": 153, "id": 27}, {"text": "(", "start": 154, "end": 155, "id": 28}, {"text": "b", "start": 155, "end": 156, "id": 29}, {"text": ")", "start": 156, "end": 157, "id": 30}, {"text": ".", "start": 157, "end": 158, "id": 31}]}
{"pdf_hash": "a8399762c0a4860d7f5c0cdee6caff71ce1301a6", "fig_key": "Figure2", "fig_uri": "18-Figure2-1.png", "text": "Figure 2. Single nanotube imaging and tracking on cells on a plasmonic gold substrate at 37 \u00baC. (a) 2D trajectory of a single CNT (same as the one in Figure 1c and 1d) moving on the cell membrane during endocytosis at 37 \u00baC. (b-d) Photoluminescence images of this particular single CNT overlaid with optical images of a cell (outlined by the dashed line) at three time points: 20 s, 73.3 s and 263.3 s after the incubation temperature stabilized at 37 \u00baC. Rectangular red bar on the bottom left of each image indicates relative fluorescence intensity. Intensity scale bar on the right indicates red as the highest signal while", "width": 1268, "height": 766, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [48, 49, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 79, 80, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122], "c": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 82, 83, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122], "d": [48, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 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{"pdf_hash": "a582d7e0806f23bec48e5154ac06add1940a52ae", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1. A 58 year-old man with chronic hepatitis C related cirrhosis and multifocal HCC, evaluated with contrast-enhanced 3 T MRI using both gadopentetate dimeglumine and gadoxetic acid. Axial fat-suppressed 3D GRE T1W LAVA FLEX images through the liver before (PRE) and after injection of gadopentetate dimeglumine (top) and gadoxetic acid (bottom) at late arterial phase (AP2), portal venous phase (PVP), late venous phase (LVP), and hepatobiliary phase (HBP for gadoxetic acid). There are two adjacent hypervascular HCCs in the central liver, which demonstrate wash-in during AP2 and wash-out on PVP and LVP for both agents. 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{"pdf_hash": "f0c42fa70efaa3f8c9e778f5f2049c7fe4cc55f2", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. High-grade B-cell lymphoma in a 38-year-old human immunodeficiency virus (HIV)\u2013positive woman who presented with abdominal pain and distention. (a) Contrast material\u2013enhanced CT scan of the midabdomen shows a very large soft-tissue mass (arrows) infiltrating the mesentery and omentum and displacing the small bowel and colon. (b) Contrast-enhanced CT scan shows hypoenhancing soft-tissue masses (arrows) in both kidneys. Note also the retroperitoneal adenopathy (arrowhead). (c) Photomicrograph (original magnification, 200; Diff-Quik stain) of a specimen obtained at fine-needle aspiration biopsy shows hypercellularity with a uniform population of malignant lymphocytes. 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{"pdf_hash": "bec29ef23be220da53345cacc19c3cf953119a57", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Dynamic computed tomography reveal a mass measuring 3 cm in size in the pancreatic tail with a cystic lesion and a solid component located on the periphery that is enhanced in the arterial phase. The densities of the solid component and spleen are very similar (a: plain, b: arterial phase, c: portal phase, d: delayed phase).", "width": 1102, "height": 904, "subcaptions": {"a": [50, 51, 52, 53], "b": [54, 55, 56, 57, 58], "c": [59, 60, 61, 62], "d": [64, 65, 66, 67]}, "subfigures": [{"id": "76f521ab-0756-47bd-806e-3f670388f1f0", "label": "a", "points": [[0.3, 7.5], [0.3, 434.1], [555.7, 434.1], [555.7, 7.5]], "color": "yellow"}, {"id": "302e01e7-2bc7-4d39-b989-4db51f67a9bc", "label": "b", "points": [[569.6, 11], [569.6, 425.4], [1095.4, 425.4], [1095.4, 11]], "color": "cyan"}, {"id": "53973aad-709a-4001-8f28-22eaa9e9a65c", "label": "c", "points": [[2, 448], [2, 871.1], [550.4, 871.1], [550.4, 448]], "color": "magenta"}, {"id": "77691ec8-5e65-490c-8c0f-672b1b3cdabc", "label": "d", "points": [[564.4, 446.3], [564.4, 867.6], [1100.6, 867.6], [1100.6, 446.3]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Dynamic", "start": 10, "end": 17, "id": 3}, {"text": "computed", "start": 18, "end": 26, "id": 4}, {"text": "tomography", "start": 27, "end": 37, "id": 5}, {"text": "reveal", "start": 38, "end": 44, "id": 6}, {"text": "a", "start": 45, "end": 46, "id": 7}, {"text": "mass", "start": 47, "end": 51, "id": 8}, {"text": "measuring", "start": 52, "end": 61, "id": 9}, {"text": "3", "start": 62, "end": 63, "id": 10}, {"text": "cm", "start": 64, "end": 66, "id": 11}, {"text": "in", "start": 67, "end": 69, "id": 12}, {"text": "size", "start": 70, "end": 74, "id": 13}, {"text": "in", "start": 75, "end": 77, "id": 14}, {"text": "the", "start": 78, "end": 81, "id": 15}, {"text": "pancreatic", "start": 82, "end": 92, "id": 16}, {"text": "tail", "start": 93, "end": 97, "id": 17}, {"text": "with", "start": 98, "end": 102, "id": 18}, {"text": "a", "start": 103, "end": 104, "id": 19}, {"text": "cystic", "start": 105, "end": 111, "id": 20}, {"text": "lesion", "start": 112, "end": 118, "id": 21}, {"text": "and", "start": 119, "end": 122, "id": 22}, {"text": "a", "start": 123, "end": 124, "id": 23}, {"text": "solid", "start": 125, "end": 130, "id": 24}, {"text": "component", "start": 131, "end": 140, "id": 25}, {"text": "located", "start": 141, "end": 148, "id": 26}, {"text": "on", "start": 149, "end": 151, "id": 27}, {"text": "the", "start": 152, "end": 155, "id": 28}, {"text": "periphery", "start": 156, "end": 165, "id": 29}, {"text": "that", "start": 166, "end": 170, "id": 30}, {"text": "is", "start": 171, "end": 173, "id": 31}, {"text": "enhanced", "start": 174, "end": 182, "id": 32}, {"text": "in", "start": 183, "end": 185, "id": 33}, {"text": "the", "start": 186, "end": 189, "id": 34}, {"text": "arterial", "start": 190, "end": 198, "id": 35}, {"text": "phase", "start": 199, "end": 204, "id": 36}, {"text": ".", "start": 204, "end": 205, "id": 37}, {"text": "The", "start": 206, "end": 209, "id": 38}, {"text": "densities", "start": 210, "end": 219, "id": 39}, {"text": "of", "start": 220, "end": 222, "id": 40}, {"text": "the", "start": 223, "end": 226, "id": 41}, {"text": "solid", "start": 227, "end": 232, "id": 42}, {"text": "component", "start": 233, "end": 242, "id": 43}, {"text": "and", "start": 243, "end": 246, "id": 44}, {"text": "spleen", "start": 247, "end": 253, "id": 45}, {"text": "are", "start": 254, "end": 257, "id": 46}, {"text": "very", "start": 258, "end": 262, "id": 47}, {"text": "similar", "start": 263, "end": 270, "id": 48}, {"text": "(", "start": 271, "end": 272, "id": 49}, {"text": "a", "start": 272, "end": 273, "id": 50}, {"text": ":", "start": 273, "end": 274, "id": 51}, {"text": "plain", "start": 275, "end": 280, "id": 52}, {"text": ",", "start": 280, "end": 281, "id": 53}, {"text": "b", "start": 282, "end": 283, "id": 54}, {"text": ":", "start": 283, "end": 284, "id": 55}, {"text": "arterial", "start": 285, "end": 293, "id": 56}, {"text": "phase", "start": 294, "end": 299, "id": 57}, {"text": ",", "start": 299, "end": 300, "id": 58}, {"text": "c", "start": 301, "end": 302, "id": 59}, {"text": ":", "start": 302, "end": 303, "id": 60}, {"text": "portal", "start": 304, "end": 310, "id": 61}, {"text": "phase", "start": 311, "end": 316, "id": 62}, {"text": ",", "start": 316, "end": 317, "id": 63}, {"text": "d", "start": 318, "end": 319, "id": 64}, {"text": ":", "start": 319, "end": 320, "id": 65}, {"text": "delayed", "start": 321, "end": 328, "id": 66}, {"text": "phase", "start": 329, "end": 334, "id": 67}, {"text": ")", "start": 334, "end": 335, "id": 68}, {"text": ".", "start": 335, "end": 336, "id": 69}]}
{"pdf_hash": "2a1bfd0caa873d0999a52d3f13c940bbbace9f02", "fig_key": "Figure3", "fig_uri": "20-Figure3-1.png", "text": "Figure 3: The optical transfer functions O m . (A): The illumination projects, onto the back focal plane of each objective lens, three disk-like images of the multi-mode fiber's end face, corresponding to diffraction orders -1, 0, and +1 from the grating. Since the fiber end face is a spatially incoherent light source, any given point in one of the six fiber images is mutually coherent only with the corresponding point in the other images, and mutually incoherent with all other points (one example of a mutually coherent point triplet in one pupil plane is shown as yellow points in A). (B): The spatial frequency components of the light amplitude forms six circular disks (here shown in cross section), corresponding to the six fiber images, and to the six point-like dots that occur in the coherent case (Fig. 2 F). (C): The illumination intensity components, which represent difference vectors between mutually coherent amplitude components, and were point-like in the coherent case (Fig. 2 G), are broadened by the incoherence into axial line segments of differing length. (D): Experimentally measured transfer functions O m for m = 0, 1, 2. The image brightness represents the magnitude of O m (k) as function of k, with a nonlinear color scaling chosen to visualize both strong and weak regions clearly. The measured O m were rotationally averaged to suppress noise. 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{"pdf_hash": "a34a564709473806fddfa4cc07de700da8e56e34", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Rho-kinase accumulates at the apical\u2013lateral border of cells surrounding the wound. (A) Cells in a monolayer of MLC-RFP cells transiently expressing EGFP\u2013Rho-kinase were ablated, and XZ images were collected. (B and C) XY images were taken before (B) and after (C) XZ imaging. EGFP\u2013Rho-kinase and MLC-RFP coaccumulated simultaneously at the apical\u2013lateral border (open arrowheads). EGFP\u2013Rho-kinase did not accumulate at the basal\u2013lateral border (closed arrowheads). Asterisks indicate the ablated cells. 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{"pdf_hash": "2b79ca9d39297ac52f3442418e55f5d26079a1e9", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Representative 20-nm-thick slices within transverse sections. The XY slices (Left) are perpendicular to the electron beam, and the XZ slices (Right) are parallel to the beam at the location indicated by the red dashed line. In A and B where the XY slices show a collection of dots near the leading edge of the septum, the corresponding XZ slices reveal streak patterns, indicating the dots are cross-sections of filaments. In C where the cells were treated with LatA, the collection of dots and streak pattern are not seen in the XY and XZ slices, respectively. 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{"pdf_hash": "093c145e9649733e4cc088d456695fd503ac1a9a", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1: A. CT on admission shows high-density heterogeneous mass in the third ventricle and obstructive hydrocephalus. B. CT image two weeks after VP-shunt procedure shows improvement of hydrocephalus. C. CT image six months after VP-shunt surgery shows enlargement of tumor mass. D. 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{"pdf_hash": "cb332898a13e914f777c8d4c93116cee95bd667c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: MRI Brain shows a heterogeneously hyperintense mass extending from planum sphenoidale and compressing both frontal lobes on T2WI sagittal images (a) with surrounding edema. The lesion shows heterogeneous postcontrast enhancement and extends to the right frontal sinus and anterior cerebral artery on T1W1 image with contrast (b)", "width": 676, "height": 386, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "6db2ea01-fb37-476c-8bb5-87a03386a90c", "label": "b", "points": [[347.6, 1.1], [347.6, 356.7], [673.3, 356.7], [673.3, 1.1]], "color": "yellow"}, {"id": "64939990-e9dd-459f-83de-7dea4e025301", "label": "a", "points": [[0.5, 1.1], [0.5, 355.6], [339.1, 355.6], [339.1, 1.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "MRI", "start": 10, "end": 13, "id": 3}, {"text": "Brain", "start": 14, "end": 19, "id": 4}, {"text": "shows", "start": 20, "end": 25, "id": 5}, {"text": "a", "start": 26, "end": 27, "id": 6}, {"text": "heterogeneously", "start": 28, "end": 43, "id": 7}, {"text": "hyperintense", "start": 44, "end": 56, "id": 8}, {"text": "mass", "start": 57, "end": 61, "id": 9}, {"text": "extending", "start": 62, "end": 71, "id": 10}, {"text": "from", "start": 72, "end": 76, "id": 11}, {"text": "planum", "start": 77, "end": 83, "id": 12}, {"text": "sphenoidale", "start": 84, "end": 95, "id": 13}, {"text": "and", "start": 96, "end": 99, "id": 14}, {"text": "compressing", "start": 100, "end": 111, "id": 15}, {"text": "both", "start": 112, "end": 116, "id": 16}, {"text": "frontal", "start": 117, "end": 124, "id": 17}, {"text": "lobes", "start": 125, "end": 130, "id": 18}, {"text": "on", "start": 131, "end": 133, "id": 19}, {"text": "T2WI", "start": 134, "end": 138, "id": 20}, {"text": "sagittal", "start": 139, "end": 147, "id": 21}, {"text": "images", "start": 148, "end": 154, "id": 22}, {"text": "(", "start": 155, "end": 156, "id": 23}, {"text": "a", "start": 156, "end": 157, "id": 24}, {"text": ")", "start": 157, "end": 158, "id": 25}, {"text": "with", "start": 159, "end": 163, "id": 26}, {"text": "surrounding", "start": 164, "end": 175, "id": 27}, {"text": "edema", "start": 176, "end": 181, "id": 28}, {"text": ".", "start": 181, "end": 182, "id": 29}, {"text": "The", "start": 183, "end": 186, "id": 30}, {"text": "lesion", "start": 187, "end": 193, "id": 31}, {"text": "shows", "start": 194, "end": 199, "id": 32}, {"text": "heterogeneous", "start": 200, "end": 213, "id": 33}, {"text": "postcontrast", "start": 214, "end": 226, "id": 34}, {"text": "enhancement", "start": 227, "end": 238, "id": 35}, {"text": "and", "start": 239, "end": 242, "id": 36}, {"text": "extends", "start": 243, "end": 250, "id": 37}, {"text": "to", "start": 251, "end": 253, "id": 38}, {"text": "the", "start": 254, "end": 257, "id": 39}, {"text": "right", "start": 258, "end": 263, "id": 40}, {"text": "frontal", "start": 264, "end": 271, "id": 41}, {"text": "sinus", "start": 272, "end": 277, "id": 42}, {"text": "and", "start": 278, "end": 281, "id": 43}, {"text": "anterior", "start": 282, "end": 290, "id": 44}, {"text": "cerebral", "start": 291, "end": 299, "id": 45}, {"text": "artery", "start": 300, "end": 306, "id": 46}, {"text": "on", "start": 307, "end": 309, "id": 47}, {"text": "T1W1", "start": 310, "end": 314, "id": 48}, {"text": "image", "start": 315, "end": 320, "id": 49}, {"text": "with", "start": 321, "end": 325, "id": 50}, {"text": "contrast", "start": 326, "end": 334, "id": 51}, {"text": "(", "start": 335, "end": 336, "id": 52}, {"text": "b", "start": 336, "end": 337, "id": 53}, {"text": ")", "start": 337, "end": 338, "id": 54}]}
{"pdf_hash": "eade76b2af12ba0c041b4c12085cb6f4a5840563", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1 (A) Axial high-resolution CT image showing a characteristic reverse halo sign in the left lower lobe, with an annular consolidation and central presence of ground glass opacity. (B) Sagittal high-resolution CT image. The reversed halo sign in image A in this plane is present as a long-shaped opacity.", "width": 544, "height": 312, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 45, 46, 47, 48, 49, 50, 51], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "c3dc30b7-ad46-4646-bf70-37bb37bf3cd4", "label": "a", "points": [[3, 2], [3, 282], [331, 282], [331, 2]], "color": "yellow"}, {"id": "ceaf5bc3-3d44-416b-9ac0-b01b06430b59", "label": "b", "points": [[334, 3], [334, 277], [543, 277], [543, 3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Axial", "start": 13, "end": 18, "id": 5}, {"text": "high", "start": 19, "end": 23, "id": 6}, {"text": "-", "start": 23, "end": 24, "id": 7}, {"text": "resolution", "start": 24, "end": 34, "id": 8}, {"text": "CT", "start": 35, "end": 37, "id": 9}, {"text": "image", "start": 38, "end": 43, "id": 10}, {"text": "showing", "start": 44, "end": 51, "id": 11}, {"text": "a", "start": 52, "end": 53, "id": 12}, {"text": "characteristic", "start": 54, "end": 68, "id": 13}, {"text": "reverse", "start": 69, "end": 76, "id": 14}, {"text": "halo", "start": 77, "end": 81, "id": 15}, {"text": "sign", "start": 82, "end": 86, "id": 16}, {"text": "in", "start": 87, "end": 89, "id": 17}, {"text": "the", "start": 90, "end": 93, "id": 18}, {"text": "left", "start": 94, "end": 98, "id": 19}, {"text": "lower", "start": 99, "end": 104, "id": 20}, {"text": "lobe", "start": 105, "end": 109, "id": 21}, {"text": ",", "start": 109, "end": 110, "id": 22}, {"text": "with", "start": 111, "end": 115, "id": 23}, {"text": "an", "start": 116, "end": 118, "id": 24}, {"text": "annular", "start": 119, "end": 126, "id": 25}, {"text": "consolidation", "start": 127, "end": 140, "id": 26}, {"text": "and", "start": 141, "end": 144, "id": 27}, {"text": "central", "start": 145, "end": 152, "id": 28}, {"text": "presence", "start": 153, "end": 161, "id": 29}, {"text": "of", "start": 162, "end": 164, "id": 30}, {"text": "ground", "start": 165, "end": 171, "id": 31}, {"text": "glass", "start": 172, "end": 177, "id": 32}, {"text": "opacity", "start": 178, "end": 185, "id": 33}, {"text": ".", "start": 185, "end": 186, "id": 34}, {"text": "(", "start": 187, "end": 188, "id": 35}, {"text": "B", "start": 188, "end": 189, "id": 36}, {"text": ")", "start": 189, "end": 190, "id": 37}, {"text": "Sagittal", "start": 191, "end": 199, "id": 38}, {"text": "high", "start": 200, "end": 204, "id": 39}, {"text": "-", "start": 204, "end": 205, "id": 40}, {"text": "resolution", "start": 205, "end": 215, "id": 41}, {"text": "CT", "start": 216, "end": 218, "id": 42}, {"text": "image", "start": 219, "end": 224, "id": 43}, {"text": ".", "start": 224, "end": 225, "id": 44}, {"text": "The", "start": 226, "end": 229, "id": 45}, {"text": "reversed", "start": 230, "end": 238, "id": 46}, {"text": "halo", "start": 239, "end": 243, "id": 47}, {"text": "sign", "start": 244, "end": 248, "id": 48}, {"text": "in", "start": 249, "end": 251, "id": 49}, {"text": "image", "start": 252, "end": 257, "id": 50}, {"text": "A", "start": 258, "end": 259, "id": 51}, {"text": "in", "start": 260, "end": 262, "id": 52}, {"text": "this", "start": 263, "end": 267, "id": 53}, {"text": "plane", "start": 268, "end": 273, "id": 54}, {"text": "is", "start": 274, "end": 276, "id": 55}, {"text": "present", "start": 277, "end": 284, "id": 56}, {"text": "as", "start": 285, "end": 287, "id": 57}, {"text": "a", "start": 288, "end": 289, "id": 58}, {"text": "long", "start": 290, "end": 294, "id": 59}, {"text": "-", "start": 294, "end": 295, "id": 60}, {"text": "shaped", "start": 295, "end": 301, "id": 61}, {"text": "opacity", "start": 302, "end": 309, "id": 62}, {"text": ".", "start": 309, "end": 310, "id": 63}]}
{"pdf_hash": "9bdb95242c4daede893bdb47e5ce7db08f042b8f", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Computed tomography scans. (A) The arrow showed a soft tissue mass with obscure boundaries and moderate enhancement in the glans penis on the arterial phase. (C) The arrow showed an enlarged inguinal lymph node with ring-like enhancement. (B and D) The arrows showed the mass and the lymph node regressed following chemotherapy.", "width": 926, "height": 576, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "c": [49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "d13084e1-27fd-4ac5-bb67-30fa73f6c81a", "label": "a", "points": [[8.8, 8.8], [8.8, 278], [456.4, 278], [456.4, 8.8]], "color": "yellow"}, {"id": "71f5072b-8ef5-4614-b8fa-d945737313ab", "label": "b", "points": [[16.1, 294], [16.1, 572], [468.1, 572], [468.1, 294]], "color": "cyan"}, {"id": "f0bd606f-8f50-4b84-bf83-8a1eca4fe394", "label": "c", "points": [[481.3, 7.3], [481.3, 280.9], [924.6, 280.9], [924.6, 7.3]], "color": "magenta"}, {"id": "549792b7-9323-4e46-a788-0ba6efb0ac99", "label": "c", "points": [[481.3, 291.1], [481.3, 563.2], [915.8, 563.2], [915.8, 291.1]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomography", "start": 19, "end": 29, "id": 4}, {"text": "scans", "start": 30, "end": 35, "id": 5}, {"text": ".", "start": 35, "end": 36, "id": 6}, {"text": "(", "start": 37, "end": 38, "id": 7}, {"text": "A", "start": 38, "end": 39, "id": 8}, {"text": ")", "start": 39, "end": 40, "id": 9}, {"text": "The", "start": 41, "end": 44, "id": 10}, {"text": "arrow", "start": 45, "end": 50, "id": 11}, {"text": "showed", "start": 51, "end": 57, "id": 12}, {"text": "a", "start": 58, "end": 59, "id": 13}, {"text": "soft", "start": 60, "end": 64, "id": 14}, {"text": "tissue", "start": 65, "end": 71, "id": 15}, {"text": "mass", "start": 72, "end": 76, "id": 16}, {"text": "with", "start": 77, "end": 81, "id": 17}, {"text": "obscure", "start": 82, "end": 89, "id": 18}, {"text": "boundaries", "start": 90, "end": 100, "id": 19}, {"text": "and", "start": 101, "end": 104, "id": 20}, {"text": "moderate", "start": 105, "end": 113, "id": 21}, {"text": "enhancement", "start": 114, "end": 125, "id": 22}, {"text": "in", "start": 126, "end": 128, "id": 23}, {"text": "the", "start": 129, "end": 132, "id": 24}, {"text": "glans", "start": 133, "end": 138, "id": 25}, {"text": "penis", "start": 139, "end": 144, "id": 26}, {"text": "on", "start": 145, "end": 147, "id": 27}, {"text": "the", "start": 148, "end": 151, "id": 28}, {"text": "arterial", "start": 152, "end": 160, "id": 29}, {"text": "phase", "start": 161, "end": 166, "id": 30}, {"text": ".", "start": 166, "end": 167, "id": 31}, {"text": "(", "start": 168, "end": 169, "id": 32}, {"text": "C", "start": 169, "end": 170, "id": 33}, {"text": ")", "start": 170, "end": 171, "id": 34}, {"text": "The", "start": 172, "end": 175, "id": 35}, {"text": "arrow", "start": 176, "end": 181, "id": 36}, {"text": "showed", "start": 182, "end": 188, "id": 37}, {"text": "an", "start": 189, "end": 191, "id": 38}, {"text": "enlarged", "start": 192, "end": 200, "id": 39}, {"text": "inguinal", "start": 201, "end": 209, "id": 40}, {"text": "lymph", "start": 210, "end": 215, "id": 41}, {"text": "node", "start": 216, "end": 220, "id": 42}, {"text": "with", "start": 221, "end": 225, "id": 43}, {"text": "ring", "start": 226, "end": 230, "id": 44}, {"text": "-", "start": 230, "end": 231, "id": 45}, {"text": "like", "start": 231, "end": 235, "id": 46}, {"text": "enhancement", "start": 236, "end": 247, "id": 47}, {"text": ".", "start": 247, "end": 248, "id": 48}, {"text": "(", "start": 249, "end": 250, "id": 49}, {"text": "B", "start": 250, "end": 251, "id": 50}, {"text": "and", "start": 252, "end": 255, "id": 51}, {"text": "D", "start": 256, "end": 257, "id": 52}, {"text": ")", "start": 257, "end": 258, "id": 53}, {"text": "The", "start": 259, "end": 262, "id": 54}, {"text": "arrows", "start": 263, "end": 269, "id": 55}, {"text": "showed", "start": 270, "end": 276, "id": 56}, {"text": "the", "start": 277, "end": 280, "id": 57}, {"text": "mass", "start": 281, "end": 285, "id": 58}, {"text": "and", "start": 286, "end": 289, "id": 59}, {"text": "the", "start": 290, "end": 293, "id": 60}, {"text": "lymph", "start": 294, "end": 299, "id": 61}, {"text": "node", "start": 300, "end": 304, "id": 62}, {"text": "regressed", "start": 305, "end": 314, "id": 63}, {"text": "following", "start": 315, "end": 324, "id": 64}, {"text": "chemotherapy", "start": 325, "end": 337, "id": 65}, {"text": ".", "start": 337, "end": 338, "id": 66}]}
{"pdf_hash": "9a60020231da04d0fdb6a538cb4341aba9b2025b", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Fig. 2. CT images of the multipurpose chest phantom showing the 8 mm low-attenuation (anterior) and high-attenuation (posterior) simulated ground-glass opacities (GGOs). These images were acquired using (a) a clinical lung cancer screening protocol (51 effective mAs) and reconstructed with filtered back-projection (FBP), or (b) and (c) a reduced tube current protocol (20 effective mAs) and reconstructed with adaptive statistical iterative reconstruction (ASIR) or model-based iterative reconstruction (MBIR), respectively.", "width": 514, "height": 1284, "subcaptions": {"a": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65], "b": [37, 38, 39, 40, 41, 68, 69, 70, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 106], "c": [37, 38, 39, 40, 41, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 96, 97, 98, 99, 100, 101, 102, 103, 106]}, "subfigures": [{"id": "7333bc2c-3fb5-4485-973f-f69aebf7c1c5", "label": "a", "points": [[1, 1.8], [1, 403.9], [512, 403.9], [512, 1.8]], "color": "yellow"}, {"id": "1d27cc75-12a1-483a-9d36-9c641891be4a", "label": "b", "points": [[0, 438.4], [0, 842.4], [515, 842.4], [515, 438.4]], "color": "cyan"}, {"id": "ed7e140a-db2f-424c-afb5-53ef4eea41c2", "label": "b", "points": [[0, 882.4], [0, 1281.4], [509, 1281.4], [509, 882.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "CT", "start": 8, "end": 10, "id": 4}, {"text": "images", "start": 11, "end": 17, "id": 5}, {"text": "of", "start": 18, "end": 20, "id": 6}, {"text": "the", "start": 21, "end": 24, "id": 7}, {"text": "multipurpose", "start": 25, "end": 37, "id": 8}, {"text": "chest", "start": 38, "end": 43, "id": 9}, {"text": "phantom", "start": 44, "end": 51, "id": 10}, {"text": "showing", "start": 52, "end": 59, "id": 11}, {"text": "the", "start": 60, "end": 63, "id": 12}, {"text": "8", "start": 64, "end": 65, "id": 13}, {"text": "mm", "start": 66, "end": 68, "id": 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162, "end": 163, "id": 33}, {"text": "GGOs", "start": 163, "end": 167, "id": 34}, {"text": ")", "start": 167, "end": 168, "id": 35}, {"text": ".", "start": 168, "end": 169, "id": 36}, {"text": "These", "start": 170, "end": 175, "id": 37}, {"text": "images", "start": 176, "end": 182, "id": 38}, {"text": "were", "start": 183, "end": 187, "id": 39}, {"text": "acquired", "start": 188, "end": 196, "id": 40}, {"text": "using", "start": 197, "end": 202, "id": 41}, {"text": "(", "start": 203, "end": 204, "id": 42}, {"text": "a", "start": 204, "end": 205, "id": 43}, {"text": ")", "start": 205, "end": 206, "id": 44}, {"text": "a", "start": 207, "end": 208, "id": 45}, {"text": "clinical", "start": 209, "end": 217, "id": 46}, {"text": "lung", "start": 218, "end": 222, "id": 47}, {"text": "cancer", "start": 223, "end": 229, "id": 48}, {"text": "screening", "start": 230, "end": 239, "id": 49}, {"text": "protocol", "start": 240, "end": 248, "id": 50}, {"text": "(", "start": 249, "end": 250, "id": 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"end": 329, "id": 70}, {"text": "and", "start": 330, "end": 333, "id": 71}, {"text": "(", "start": 334, "end": 335, "id": 72}, {"text": "c", "start": 335, "end": 336, "id": 73}, {"text": ")", "start": 336, "end": 337, "id": 74}, {"text": "a", "start": 338, "end": 339, "id": 75}, {"text": "reduced", "start": 340, "end": 347, "id": 76}, {"text": "tube", "start": 348, "end": 352, "id": 77}, {"text": "current", "start": 353, "end": 360, "id": 78}, {"text": "protocol", "start": 361, "end": 369, "id": 79}, {"text": "(", "start": 370, "end": 371, "id": 80}, {"text": "20", "start": 371, "end": 373, "id": 81}, {"text": "effective", "start": 374, "end": 383, "id": 82}, {"text": "mAs", "start": 384, "end": 387, "id": 83}, {"text": ")", "start": 387, "end": 388, "id": 84}, {"text": "and", "start": 389, "end": 392, "id": 85}, {"text": "reconstructed", "start": 393, "end": 406, "id": 86}, {"text": "with", "start": 407, "end": 411, "id": 87}, {"text": "adaptive", "start": 412, "end": 420, "id": 88}, {"text": "statistical", "start": 421, "end": 432, "id": 89}, {"text": "iterative", "start": 433, "end": 442, "id": 90}, {"text": "reconstruction", "start": 443, "end": 457, "id": 91}, {"text": "(", "start": 458, "end": 459, "id": 92}, {"text": "ASIR", "start": 459, "end": 463, "id": 93}, {"text": ")", "start": 463, "end": 464, "id": 94}, {"text": "or", "start": 465, "end": 467, "id": 95}, {"text": "model", "start": 468, "end": 473, "id": 96}, {"text": "-", "start": 473, "end": 474, "id": 97}, {"text": "based", "start": 474, "end": 479, "id": 98}, {"text": "iterative", "start": 480, "end": 489, "id": 99}, {"text": "reconstruction", "start": 490, "end": 504, "id": 100}, {"text": "(", "start": 505, "end": 506, "id": 101}, {"text": "MBIR", "start": 506, "end": 510, "id": 102}, {"text": ")", "start": 510, "end": 511, "id": 103}, {"text": ",", "start": 511, "end": 512, "id": 104}, {"text": "respectively", "start": 513, "end": 525, "id": 105}, {"text": ".", "start": 525, "end": 526, "id": 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{"pdf_hash": "7254734a639af3034c7947f418da3d07e0654aeb", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "FIGURE 6. Computed tomographic (CT) images of a 67-yr-old female with fibrosing pulmonary sarcoidosis with honeycombing pattern and pulmonary hypertension. a) Honeycombing predominates in the upper and perihilar regions, and along the bronchovascular bundles. Note the various sizes of the cysts. b) Contrast-enhanced CT shows the widest diameter of the main pulmonary artery with a diameter superior to that of the ascending aorta and slight vascular compression by enlarged mediastinal lymph nodes.", "width": 684, "height": 878, "subcaptions": {"a": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "b": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85]}, "subfigures": [{"id": "75bdd5f7-9895-438b-8811-71457b847c34", "label": "a", "points": [[0.6, 0.9], [0.6, 434.2], [679.1, 434.2], [679.1, 0.9]], "color": "yellow"}, {"id": "9cbfb49d-e523-4d5e-bc1f-2af21a5e5d3f", "label": "b", "points": [[4.9, 450.4], [4.9, 872.9], [678.1, 872.9], [678.1, 450.4]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 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120, "end": 127, "id": 21}, {"text": "and", "start": 128, "end": 131, "id": 22}, {"text": "pulmonary", "start": 132, "end": 141, "id": 23}, {"text": "hypertension", "start": 142, "end": 154, "id": 24}, {"text": ".", "start": 154, "end": 155, "id": 25}, {"text": "a", "start": 156, "end": 157, "id": 26}, {"text": ")", "start": 157, "end": 158, "id": 27}, {"text": "Honeycombing", "start": 159, "end": 171, "id": 28}, {"text": "predominates", "start": 172, "end": 184, "id": 29}, {"text": "in", "start": 185, "end": 187, "id": 30}, {"text": "the", "start": 188, "end": 191, "id": 31}, {"text": "upper", "start": 192, "end": 197, "id": 32}, {"text": "and", "start": 198, "end": 201, "id": 33}, {"text": "perihilar", "start": 202, "end": 211, "id": 34}, {"text": "regions", "start": 212, "end": 219, "id": 35}, {"text": ",", "start": 219, "end": 220, "id": 36}, {"text": "and", "start": 221, "end": 224, "id": 37}, {"text": "along", "start": 225, "end": 230, "id": 38}, {"text": "the", "start": 231, "end": 234, "id": 39}, {"text": "bronchovascular", "start": 235, "end": 250, "id": 40}, {"text": "bundles", "start": 251, "end": 258, "id": 41}, {"text": ".", "start": 258, "end": 259, "id": 42}, {"text": "Note", "start": 260, "end": 264, "id": 43}, {"text": "the", "start": 265, "end": 268, "id": 44}, {"text": "various", "start": 269, "end": 276, "id": 45}, {"text": "sizes", "start": 277, "end": 282, "id": 46}, {"text": "of", "start": 283, "end": 285, "id": 47}, {"text": "the", "start": 286, "end": 289, "id": 48}, {"text": "cysts", "start": 290, "end": 295, "id": 49}, {"text": ".", "start": 295, "end": 296, "id": 50}, {"text": "b", "start": 297, "end": 298, "id": 51}, {"text": ")", "start": 298, "end": 299, "id": 52}, {"text": "Contrast", "start": 300, "end": 308, "id": 53}, {"text": "-", "start": 308, "end": 309, "id": 54}, {"text": "enhanced", "start": 309, "end": 317, "id": 55}, {"text": "CT", "start": 318, "end": 320, "id": 56}, {"text": "shows", "start": 321, "end": 326, "id": 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{"pdf_hash": "ba28e02b951fdc3a339bf0e09190294097e3bceb", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Gastroenterological endoscopy findings. Gastroenterological endoscopy revealed tumor lesion with widespread ulceration in the gastric cardia, a in October 2009 and b in June 2011. The stomach lesion decreased after 2 years of chemo-immunotherapy, preoperatively", "width": 1006, "height": 402, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 29], "b": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "33435e85-215f-4b6c-9760-60f21c2555c3", "label": "a", "points": [[34.2, 22], [34.2, 368.4], [493.5, 368.4], [493.5, 22]], "color": "yellow"}, {"id": "a1fbf96e-dcbc-4040-b298-6fee4240d33d", "label": "b", "points": [[504.6, 23.6], [504.6, 371.6], [970.3, 371.6], [970.3, 23.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Gastroenterological", "start": 7, "end": 26, "id": 3}, {"text": "endoscopy", "start": 27, "end": 36, "id": 4}, {"text": "findings", "start": 37, "end": 45, "id": 5}, {"text": ".", "start": 45, "end": 46, "id": 6}, {"text": "Gastroenterological", "start": 47, "end": 66, "id": 7}, {"text": "endoscopy", "start": 67, "end": 76, "id": 8}, {"text": "revealed", "start": 77, "end": 85, "id": 9}, {"text": "tumor", "start": 86, "end": 91, "id": 10}, {"text": "lesion", "start": 92, "end": 98, "id": 11}, {"text": "with", "start": 99, "end": 103, "id": 12}, {"text": "widespread", "start": 104, "end": 114, "id": 13}, {"text": "ulceration", "start": 115, "end": 125, "id": 14}, {"text": "in", "start": 126, "end": 128, "id": 15}, {"text": "the", "start": 129, "end": 132, "id": 16}, {"text": "gastric", "start": 133, "end": 140, "id": 17}, {"text": "cardia", "start": 141, "end": 147, "id": 18}, {"text": ",", "start": 147, "end": 148, "id": 19}, {"text": "a", "start": 149, "end": 150, "id": 20}, {"text": "in", "start": 151, "end": 153, "id": 21}, {"text": "October", "start": 154, "end": 161, "id": 22}, {"text": "2009", "start": 162, "end": 166, "id": 23}, {"text": "and", "start": 167, "end": 170, "id": 24}, {"text": "b", "start": 171, "end": 172, "id": 25}, {"text": "in", "start": 173, "end": 175, "id": 26}, {"text": "June", "start": 176, "end": 180, "id": 27}, {"text": "2011", "start": 181, "end": 185, "id": 28}, {"text": ".", "start": 185, "end": 186, "id": 29}, {"text": "The", "start": 187, "end": 190, "id": 30}, {"text": "stomach", "start": 191, "end": 198, "id": 31}, {"text": "lesion", "start": 199, "end": 205, "id": 32}, {"text": "decreased", "start": 206, "end": 215, "id": 33}, {"text": "after", "start": 216, "end": 221, "id": 34}, {"text": "2", "start": 222, "end": 223, "id": 35}, {"text": "years", "start": 224, "end": 229, "id": 36}, {"text": "of", "start": 230, "end": 232, "id": 37}, {"text": "chemo", "start": 233, "end": 238, "id": 38}, {"text": "-", "start": 238, "end": 239, "id": 39}, {"text": "immunotherapy", "start": 239, "end": 252, "id": 40}, {"text": ",", "start": 252, "end": 253, "id": 41}, {"text": "preoperatively", "start": 254, "end": 268, "id": 42}]}
{"pdf_hash": "c32e88045ccca1c276b5ac8e8343dcfbfd5052de", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Fig. 6 Time-spatial labeling inversion pulse (Time-SLIP) with pencil beam pulse dynamic images (the first\u2013third dynamic images) of a patient after endoscopic third ventriculostomy for cerebral aqueduct occlusion caused by a hematoma. The labeling pulses were applied to the posterior (a), middle (b), and anterior (c) portions of the third ventricle.", "width": 670, "height": 716, "subcaptions": {"a": [66, 67, 68, 69, 70, 71, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54], "b": [66, 67, 68, 69, 70, 71, 44, 45, 46, 47, 48, 49, 50, 56, 57, 58, 59], "c": [64, 65, 66, 67, 68, 69, 70, 71, 44, 45, 46, 47, 48, 49, 50, 62, 63]}, "subfigures": [{"id": "519b3bb1-485d-4318-9462-7e0b8d37284d", "label": "a", "points": [[5.9, 1.4], [5.9, 214.2], [223.9, 214.2], [223.9, 1.4]], "color": "yellow"}, {"id": "73827340-91be-406a-bb88-ba3a2e18d29f", "label": "a", "points": [[231.3, 4.6], [231.3, 215.2], [446.2, 215.2], [446.2, 4.6]], "color": "cyan"}, {"id": "b17514cc-7508-469d-9aba-0ee5c3c87f0d", "label": "a", "points": [[454.6, 3.5], [454.6, 214.2], [665.2, 214.2], [665.2, 3.5]], "color": "magenta"}, {"id": "5cb82c93-33a1-4874-890a-6b1968cdcbe1", "label": "b", "points": [[5.9, 219.4], [5.9, 434.3], [217.5, 434.3], [217.5, 219.4]], "color": 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{"pdf_hash": "8a2f7efe4dafd33617bd9a1ba9a0b12192689c10", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 Retinography (a) and fundus autofluorescence imaging (b) showing new lesions. The patient had initiated a second tapered course of prednisone. At this point, a dexamethasone intravitreal implant was indicated", "width": 846, "height": 344, "subcaptions": {"a": [3, 4, 5, 6, 14, 15, 16, 17], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17]}, "subfigures": [{"id": "c6e7cabd-4fdb-4015-87ac-1e09a2acdfea", "label": "a", "points": [[32.1, 5.3], [32.1, 308.7], [425, 308.7], [425, 5.3]], "color": "yellow"}, {"id": "657cce94-c30d-412a-8586-86307dc577b5", "label": "b", "points": [[427.7, 6.7], [427.7, 303.4], [812.6, 303.4], [812.6, 6.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Retinography", "start": 7, "end": 19, "id": 3}, {"text": "(", "start": 20, "end": 21, "id": 4}, {"text": "a", "start": 21, "end": 22, "id": 5}, {"text": ")", "start": 22, "end": 23, "id": 6}, {"text": "and", "start": 24, "end": 27, "id": 7}, {"text": "fundus", "start": 28, "end": 34, "id": 8}, {"text": "autofluorescence", "start": 35, "end": 51, "id": 9}, {"text": "imaging", "start": 52, "end": 59, "id": 10}, {"text": "(", "start": 60, "end": 61, "id": 11}, {"text": "b", "start": 61, "end": 62, "id": 12}, {"text": ")", "start": 62, "end": 63, "id": 13}, {"text": "showing", "start": 64, "end": 71, "id": 14}, {"text": "new", "start": 72, "end": 75, "id": 15}, {"text": "lesions", "start": 76, "end": 83, "id": 16}, {"text": ".", "start": 83, "end": 84, "id": 17}, {"text": "The", "start": 85, "end": 88, "id": 18}, {"text": "patient", "start": 89, "end": 96, "id": 19}, {"text": "had", "start": 97, "end": 100, "id": 20}, {"text": "initiated", "start": 101, "end": 110, "id": 21}, {"text": "a", "start": 111, "end": 112, "id": 22}, {"text": "second", "start": 113, "end": 119, "id": 23}, {"text": "tapered", "start": 120, "end": 127, "id": 24}, {"text": "course", "start": 128, "end": 134, "id": 25}, {"text": "of", "start": 135, "end": 137, "id": 26}, {"text": "prednisone", "start": 138, "end": 148, "id": 27}, {"text": ".", "start": 148, "end": 149, "id": 28}, {"text": "At", "start": 150, "end": 152, "id": 29}, {"text": "this", "start": 153, "end": 157, "id": 30}, {"text": "point", "start": 158, "end": 163, "id": 31}, {"text": ",", "start": 163, "end": 164, "id": 32}, {"text": "a", "start": 165, "end": 166, "id": 33}, {"text": "dexamethasone", "start": 167, "end": 180, "id": 34}, {"text": "intravitreal", "start": 181, "end": 193, "id": 35}, {"text": "implant", "start": 194, "end": 201, "id": 36}, {"text": "was", "start": 202, "end": 205, "id": 37}, {"text": "indicated", "start": 206, "end": 215, "id": 38}]}
{"pdf_hash": "37487bc4150fc0feb7a3006727345ad820fabb7e", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. (A) Lateral radiograph showing a notching of the anterior femoral cortex after total knee arthroplasty. (B) Lateral radiograph at postoperative 2 years showing a displaced supracondylar femoral fracture at the site of cortical notching.", "width": 680, "height": 468, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43]}, "subfigures": [{"id": "ffbe4642-c1dd-4a92-8927-812760cf61a1", "label": "a", "points": [[4.9, 4.1], [4.9, 464.9], [336.8, 464.9], [336.8, 4.1]], "color": "yellow"}, {"id": "5b89c4c3-d717-40b2-a038-c660a0a9c27f", "label": "b", "points": [[350.8, 0.9], [350.8, 462.8], [677.3, 462.8], [677.3, 0.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Lateral", "start": 12, "end": 19, "id": 7}, {"text": "radiograph", "start": 20, "end": 30, "id": 8}, {"text": "showing", "start": 31, "end": 38, "id": 9}, {"text": "a", "start": 39, "end": 40, "id": 10}, {"text": "notching", "start": 41, "end": 49, "id": 11}, {"text": "of", "start": 50, "end": 52, "id": 12}, {"text": "the", "start": 53, "end": 56, "id": 13}, {"text": "anterior", "start": 57, "end": 65, "id": 14}, {"text": "femoral", "start": 66, "end": 73, "id": 15}, {"text": "cortex", "start": 74, "end": 80, "id": 16}, {"text": "after", "start": 81, "end": 86, "id": 17}, {"text": "total", "start": 87, "end": 92, "id": 18}, {"text": "knee", "start": 93, "end": 97, "id": 19}, {"text": "arthroplasty", "start": 98, "end": 110, "id": 20}, {"text": ".", "start": 110, "end": 111, "id": 21}, {"text": "(", "start": 112, "end": 113, "id": 22}, {"text": "B", "start": 113, "end": 114, "id": 23}, {"text": ")", "start": 114, "end": 115, "id": 24}, {"text": "Lateral", "start": 116, "end": 123, "id": 25}, {"text": "radiograph", "start": 124, "end": 134, "id": 26}, {"text": "at", "start": 135, "end": 137, "id": 27}, {"text": "postoperative", "start": 138, "end": 151, "id": 28}, {"text": "2", "start": 152, "end": 153, "id": 29}, {"text": "years", "start": 154, "end": 159, "id": 30}, {"text": "showing", "start": 160, "end": 167, "id": 31}, {"text": "a", "start": 168, "end": 169, "id": 32}, {"text": "displaced", "start": 170, "end": 179, "id": 33}, {"text": "supracondylar", "start": 180, "end": 193, "id": 34}, {"text": "femoral", "start": 194, "end": 201, "id": 35}, {"text": "fracture", "start": 202, "end": 210, "id": 36}, {"text": "at", "start": 211, "end": 213, "id": 37}, {"text": "the", "start": 214, "end": 217, "id": 38}, {"text": "site", "start": 218, "end": 222, "id": 39}, {"text": "of", "start": 223, "end": 225, "id": 40}, {"text": "cortical", "start": 226, "end": 234, "id": 41}, {"text": "notching", "start": 235, "end": 243, "id": 42}, {"text": ".", "start": 243, "end": 244, "id": 43}]}
{"pdf_hash": "6e6144a1e3f0ea6145d8104aea41e05e38f133fe", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. No Evidence of Ependymal Enhancement on MRI (Group B). Axial (A) and coronal (B) gadolinium-enhanced T1-weighted images showing a left parietal ring enhancing lesion not contacting the ventricular wall.", "width": 772, "height": 498, "subcaptions": {"a": [15, 16, 17, 18, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "aef91b69-23ce-4592-8938-d66bada6b320", "label": "a", "points": [[33.1, 4.9], [33.1, 468.3], [369.7, 468.3], [369.7, 4.9]], "color": "yellow"}, {"id": "bfbe0b0c-74dd-4ccb-99c5-b4585f8089dc", "label": "b", "points": [[374.6, 6.1], [374.6, 468.3], [769.8, 468.3], [769.8, 6.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "No", "start": 10, "end": 12, "id": 3}, {"text": "Evidence", "start": 13, "end": 21, "id": 4}, {"text": "of", "start": 22, "end": 24, "id": 5}, {"text": "Ependymal", "start": 25, "end": 34, "id": 6}, {"text": "Enhancement", "start": 35, "end": 46, "id": 7}, {"text": "on", "start": 47, "end": 49, "id": 8}, {"text": "MRI", "start": 50, "end": 53, "id": 9}, {"text": "(", "start": 54, "end": 55, "id": 10}, {"text": "Group", "start": 55, "end": 60, "id": 11}, {"text": "B", "start": 61, "end": 62, "id": 12}, {"text": ")", "start": 62, "end": 63, "id": 13}, {"text": ".", "start": 63, "end": 64, "id": 14}, {"text": "Axial", "start": 65, "end": 70, "id": 15}, {"text": "(", "start": 71, "end": 72, "id": 16}, {"text": "A", "start": 72, "end": 73, "id": 17}, {"text": ")", "start": 73, "end": 74, "id": 18}, {"text": "and", "start": 75, "end": 78, "id": 19}, {"text": "coronal", "start": 79, "end": 86, "id": 20}, {"text": "(", "start": 87, "end": 88, "id": 21}, {"text": "B", "start": 88, "end": 89, "id": 22}, {"text": ")", "start": 89, "end": 90, "id": 23}, {"text": "gadolinium", "start": 91, "end": 101, "id": 24}, {"text": "-", "start": 101, "end": 102, "id": 25}, {"text": "enhanced", "start": 102, "end": 110, "id": 26}, {"text": "T1-weighted", "start": 111, "end": 122, "id": 27}, {"text": "images", "start": 123, "end": 129, "id": 28}, {"text": "showing", "start": 130, "end": 137, "id": 29}, {"text": "a", "start": 138, "end": 139, "id": 30}, {"text": "left", "start": 140, "end": 144, "id": 31}, {"text": "parietal", "start": 145, "end": 153, "id": 32}, {"text": "ring", "start": 154, "end": 158, "id": 33}, {"text": "enhancing", "start": 159, "end": 168, "id": 34}, {"text": "lesion", "start": 169, "end": 175, "id": 35}, {"text": "not", "start": 176, "end": 179, "id": 36}, {"text": "contacting", "start": 180, "end": 190, "id": 37}, {"text": "the", "start": 191, "end": 194, "id": 38}, {"text": "ventricular", "start": 195, "end": 206, "id": 39}, {"text": "wall", "start": 207, "end": 211, "id": 40}, {"text": ".", "start": 211, "end": 212, "id": 41}]}
{"pdf_hash": "006228c8600560d8717b56f5c22190b2dc1ac843", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3 Maximum intensity projection images and fusion images. a 18F-FDG, b 11CMET, and c 11C-4DST PET images obtained in a 63-yearold man (Patient 1) with MM (IgA-j). Numerous active lesions are visible in the three maximum intensity projection images. The fusion images are for the cross-section at the level of the red lines (d). The lesion in the right ischium (bold arrow) was positive on all three PET scans. 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{"pdf_hash": "19e337940874ea3b8f9d44a57a2eab684ee1e7e1", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 Brain magnetic resonance imaging at four weeks of treatment in axial multiple sequences. Decrease of the level of debris layering the occipital horns of the lateral ventricles in all sequences: axial diffusion b1000 (a), axial T1 gadolinium (b) and axial T2 fluid attenuated inversion recovery (FLAIR) gadolinium sequences (c). Clear decrease of the periventricular hyperintensities and ependymal enhancement in T1 with gadolinium (b) and T2 FLAIR gadolinium (c) sequences. Decrease of b1000 DWI hyperintensities. 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{"pdf_hash": "2a5141ddefe656cf6dcfd82f61dda1f55c91a844", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. A 59-year-old man with idiopathic synovial osteochondromatosis of the left hip. A. Anteoposterior radiograph of the left hip shows juxta-articular osteopenia and joint-space narrowing of the left hip joint (arrowhead). B. T1-weighted coronal MR image of the same patient depicts an iso-intense intra-articular lesion (arrows). C. T2-weighted image, obtained at the same level as in B, shows an intra-articular body of low signal intensity (curved arrow). 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{"pdf_hash": "ac5b9483a305ea3c32d06fc46435e955f82b567a", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Case 1. Preoperative axial (A), coronal (b), and sagittal (C) contrast-enhanced MR images showing a 38-mm multicystic lesion that extends into the third ventricle and hypothalamus, compatible with the diagnosis of recurrent craniopharyngioma and fusiform dilation of the right-sided supraclinoid segment of the ICA (arrows).", "width": 1400, "height": 580, "subcaptions": {"a": [7, 8, 9, 10, 11, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65], "b": [7, 13, 14, 15, 16, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65]}, "subfigures": [{"id": "6ed7ed15-ca05-4a36-aa41-ff66f5d5041b", "label": "a", "points": [[5.5, -0.7], [5.5, 547.8], [478.9, 547.8], [478.9, -0.7]], "color": "yellow"}, {"id": "c72a8919-0512-4ba8-9d31-7ba29e6ba29d", "label": "b", "points": [[489.9, 1.5], [489.9, 550], [930.1, 550], [930.1, 1.5]], "color": "cyan"}, {"id": "49a14491-a0b8-4aaa-af98-46bfa2cc82bc", "label": "c", "points": [[939.6, 8.9], [939.6, 545.8], [1394.5, 545.8], [1394.5, 8.9]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Case", "start": 8, "end": 12, "id": 4}, {"text": "1", "start": 13, "end": 14, "id": 5}, {"text": ".", "start": 14, "end": 15, "id": 6}, {"text": "Preoperative", "start": 16, "end": 28, "id": 7}, {"text": "axial", "start": 29, "end": 34, "id": 8}, {"text": "(", "start": 35, "end": 36, "id": 9}, {"text": "A", "start": 36, "end": 37, "id": 10}, {"text": ")", "start": 37, "end": 38, "id": 11}, {"text": ",", "start": 38, "end": 39, "id": 12}, {"text": "coronal", "start": 40, "end": 47, "id": 13}, {"text": "(", "start": 48, "end": 49, "id": 14}, {"text": "b", "start": 49, "end": 50, "id": 15}, {"text": ")", "start": 50, "end": 51, "id": 16}, {"text": ",", "start": 51, "end": 52, "id": 17}, {"text": "and", "start": 53, "end": 56, "id": 18}, {"text": "sagittal", "start": 57, "end": 65, "id": 19}, {"text": "(", "start": 66, "end": 67, "id": 20}, {"text": "C", "start": 67, "end": 68, "id": 21}, {"text": ")", "start": 68, "end": 69, "id": 22}, {"text": "contrast", "start": 70, "end": 78, "id": 23}, {"text": "-", "start": 78, "end": 79, "id": 24}, {"text": "enhanced", "start": 79, "end": 87, "id": 25}, {"text": "MR", "start": 88, "end": 90, "id": 26}, {"text": "images", "start": 91, "end": 97, "id": 27}, {"text": "showing", "start": 98, "end": 105, "id": 28}, {"text": "a", "start": 106, "end": 107, "id": 29}, {"text": "38-mm", "start": 108, "end": 113, "id": 30}, {"text": "multicystic", "start": 114, "end": 125, "id": 31}, {"text": "lesion", "start": 126, "end": 132, "id": 32}, {"text": "that", "start": 133, "end": 137, "id": 33}, {"text": "extends", "start": 138, "end": 145, "id": 34}, {"text": "into", "start": 146, "end": 150, "id": 35}, {"text": "the", "start": 151, "end": 154, "id": 36}, {"text": "third", "start": 155, "end": 160, "id": 37}, {"text": "ventricle", "start": 161, "end": 170, "id": 38}, {"text": "and", "start": 171, "end": 174, "id": 39}, {"text": "hypothalamus", "start": 175, "end": 187, "id": 40}, {"text": ",", "start": 187, "end": 188, "id": 41}, {"text": "compatible", "start": 189, "end": 199, "id": 42}, {"text": "with", "start": 200, "end": 204, "id": 43}, {"text": "the", "start": 205, "end": 208, "id": 44}, {"text": "diagnosis", "start": 209, "end": 218, "id": 45}, {"text": "of", "start": 219, "end": 221, "id": 46}, {"text": "recurrent", "start": 222, "end": 231, "id": 47}, {"text": "craniopharyngioma", "start": 232, "end": 249, "id": 48}, {"text": "and", "start": 250, "end": 253, "id": 49}, {"text": "fusiform", "start": 254, "end": 262, "id": 50}, {"text": "dilation", "start": 263, "end": 271, "id": 51}, {"text": "of", "start": 272, "end": 274, "id": 52}, {"text": "the", "start": 275, "end": 278, "id": 53}, {"text": "right", "start": 279, "end": 284, "id": 54}, {"text": "-", "start": 284, "end": 285, "id": 55}, {"text": "sided", "start": 285, "end": 290, "id": 56}, {"text": "supraclinoid", "start": 291, "end": 303, "id": 57}, {"text": "segment", "start": 304, "end": 311, "id": 58}, {"text": "of", "start": 312, "end": 314, "id": 59}, {"text": "the", "start": 315, "end": 318, "id": 60}, {"text": "ICA", "start": 319, "end": 322, "id": 61}, {"text": "(", "start": 323, "end": 324, "id": 62}, {"text": "arrows", "start": 324, "end": 330, "id": 63}, {"text": ")", "start": 330, "end": 331, "id": 64}, {"text": ".", "start": 331, "end": 332, "id": 65}]}
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{"pdf_hash": "f006811537506542abe2827beda11f105feefdae", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1. Computed tomography (CT) images in a 26-year-old woman before and after inferior vena cava (IVC) filter removal. a. Before IVC filter removal, CT image in the coronal plane using a maximum intensity projection reconstruction shows IVC filter (arrow). b. Before IVC filter removal, CT image in the transverse plane shows IVC filter and filter legs (arrowheads) protruding outside the IVC wall. c. 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{"pdf_hash": "59499474b5569e6aefeb5c11dc73925fd1aa4402", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Computed tomography scans with (A) axial, (B) coronal, and (C) sagittal views. Yellow arrow identifies lesion. Tumor has solid and cystic components with loss of fat plane between the mass and anus.", "width": 1060, "height": 896, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 21, 22], "b": [2, 3, 4, 5, 11, 12, 13, 14, 21, 22], "c": [2, 3, 4, 5, 17, 18, 19, 20, 21, 22]}, "subfigures": [{"id": "b145d4f8-3a34-443a-8c67-142193253c4b", "label": "a", "points": [[31, 0], [31, 420.3], [613.7, 420.3], [613.7, 0]], "color": "yellow"}, {"id": "49d853c2-96e4-43d8-bfd0-1bf356bfd744", "label": "b", "points": [[638.8, 0], [638.8, 418.6], [1022.3, 418.6], [1022.3, 0]], "color": "cyan"}, {"id": "f9b65431-a3d4-49f4-8549-a75e6ed5843a", "label": "c", "points": [[381, 442.1], [381, 864.1], [690.8, 864.1], [690.8, 442.1]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Computed", "start": 9, "end": 17, "id": 2}, {"text": "tomography", "start": 18, "end": 28, "id": 3}, {"text": "scans", "start": 29, "end": 34, "id": 4}, {"text": "with", "start": 35, "end": 39, "id": 5}, {"text": "(", "start": 40, "end": 41, "id": 6}, {"text": "A", "start": 41, "end": 42, "id": 7}, {"text": ")", "start": 42, "end": 43, "id": 8}, {"text": "axial", "start": 44, "end": 49, "id": 9}, {"text": ",", "start": 49, "end": 50, "id": 10}, {"text": "(", "start": 51, "end": 52, "id": 11}, {"text": "B", "start": 52, "end": 53, "id": 12}, {"text": ")", "start": 53, "end": 54, "id": 13}, {"text": "coronal", "start": 55, "end": 62, "id": 14}, {"text": ",", "start": 62, "end": 63, "id": 15}, {"text": "and", "start": 64, "end": 67, "id": 16}, {"text": "(", "start": 68, "end": 69, "id": 17}, {"text": "C", "start": 69, "end": 70, "id": 18}, {"text": ")", "start": 70, "end": 71, "id": 19}, {"text": "sagittal", "start": 72, "end": 80, "id": 20}, {"text": "views", "start": 81, "end": 86, "id": 21}, {"text": ".", "start": 86, "end": 87, "id": 22}, {"text": "Yellow", "start": 88, "end": 94, "id": 23}, {"text": "arrow", "start": 95, "end": 100, "id": 24}, {"text": "identifies", "start": 101, "end": 111, "id": 25}, {"text": "lesion", "start": 112, "end": 118, "id": 26}, {"text": ".", "start": 118, "end": 119, "id": 27}, {"text": "Tumor", "start": 120, "end": 125, "id": 28}, {"text": "has", "start": 126, "end": 129, "id": 29}, {"text": "solid", "start": 130, "end": 135, "id": 30}, {"text": "and", "start": 136, "end": 139, "id": 31}, {"text": "cystic", "start": 140, "end": 146, "id": 32}, {"text": "components", "start": 147, "end": 157, "id": 33}, {"text": "with", "start": 158, "end": 162, "id": 34}, {"text": "loss", "start": 163, "end": 167, "id": 35}, {"text": "of", "start": 168, "end": 170, "id": 36}, {"text": "fat", "start": 171, "end": 174, "id": 37}, {"text": "plane", "start": 175, "end": 180, "id": 38}, {"text": "between", "start": 181, "end": 188, "id": 39}, {"text": "the", "start": 189, "end": 192, "id": 40}, {"text": "mass", "start": 193, "end": 197, "id": 41}, {"text": "and", "start": 198, "end": 201, "id": 42}, {"text": "anus", "start": 202, "end": 206, "id": 43}, {"text": ".", "start": 206, "end": 207, "id": 44}]}
{"pdf_hash": "55681429c3ab076459080b6abdf56b6f52f0e8be", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Figure 2. Results from the traditional mass-univariate fMRI analysis. (a\u2013e) Brain regions stronger activated in response to chosen vs. not chosen packages: a) Left inferior parietal gyrus; b/c) left caudate/putamen/pallidum and right putamen; d/e) Border of right middle occipital gyrus and middle temporal gyrus. (f) Brain regions modulated by absolute attractiveness in the first product presentation period: a cluster stretching from the left superior frontal gyrus to the middle frontal gyrus. 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{"pdf_hash": "21170ab90672e89b35d4d58294061fed6d1e4d0d", "fig_key": "Figure18", "fig_uri": "8-Figure18-1.png", "text": "Fig. 18 Liver metastasis. Images (a) and (b), obtained from the standard ultrasound machine, show multiple hypoechoic lesions (arrows) scattered in both lobes of the liver, which is suggestive of metastasis. 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{"pdf_hash": "3c24715b8b44cd35521ed65a38c6398a40852f0f", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Localization of SNpr infusion sites in monkey. (A) Coronal planes from the public domain Rhesus Macaque \u201cRed\u201d Symmetrical Brain Atlas (Laboratory of Neuropsychology, National Insitute of Mental Health) showing SNpr (ventral dashed ellipses) as measured by distance from the interaural plane: anterior (+9.0 mm), central (+8.0 mm), and posterior (+7.0 mm). Solid symbols indicate infusion sites for each animal; dose of MUS administered was 9nmol per 1ul for all animals. The sites were reconstructed from in vivo MRI, postmortem MRI, or histology for all animals (SL, AB, TH, NO, and YO). (B) Three representative images (animals YO, TH, and AB) showing tungsten electrodes placed in SNpr during in vivo MRI, needle tracks indicating infusion sites in postmortem high-resolution MRI, and Nissl-stained histology. In the in vivo images, electrodes were placed dorsal to the SNpr and coordinates were adjusted prior to experimental drug infusions. Images correspond to their respective planes in A. The arrows point to the tips of cannula tracks in both postmortem and histological images. (C) MR image (animal YO) following infusion of gadolinium (5 mM, 1ul) into the medial SNpr. White area shows hypersignal (3 mm in diameter) indicating diffusion of the 1ul volume 60 min after infusion. MUS infused in this site in SNpr evoked motor response indicated in Table\u00a01. LGN, lateral geniculate nucleus; SNpr, substantia nigra pars reticulata; III, third ventricle. The scale bar shown for the photomicrograph in Panel B, (Animal AB) = 5 mm. 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{"pdf_hash": "4522e08b70ad0da74710ed3b7c4ac2d1e83ffed8", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Figure 5: (a) CT showed free air around the right lateral region (yellow arrows). (b) Intraoperative findings showed perforation of the cecum with no obvious masses (yellow arrow).", "width": 1132, "height": 556, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "5204d1fb-7980-407d-b7ed-0f171cabed46", "label": "a", "points": [[26.8, 0], [26.8, 518.6], [550.8, 518.6], [550.8, 0]], "color": "yellow"}, {"id": "b71a9c94-def5-4e8e-aac6-e5b32cdb42b3", "label": "b", "points": [[577.6, 8.9], [577.6, 518.6], [1098, 518.6], [1098, 8.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "CT", "start": 14, "end": 16, "id": 6}, {"text": "showed", "start": 17, "end": 23, "id": 7}, {"text": "free", "start": 24, "end": 28, "id": 8}, {"text": "air", "start": 29, "end": 32, "id": 9}, {"text": "around", "start": 33, "end": 39, "id": 10}, {"text": "the", "start": 40, "end": 43, "id": 11}, {"text": "right", "start": 44, "end": 49, "id": 12}, {"text": "lateral", "start": 50, "end": 57, "id": 13}, {"text": "region", "start": 58, "end": 64, "id": 14}, {"text": "(", "start": 65, "end": 66, "id": 15}, {"text": "yellow", "start": 66, "end": 72, "id": 16}, {"text": "arrows", "start": 73, "end": 79, "id": 17}, {"text": ")", "start": 79, "end": 80, "id": 18}, {"text": ".", "start": 80, "end": 81, "id": 19}, {"text": "(", "start": 82, "end": 83, "id": 20}, {"text": "b", "start": 83, "end": 84, "id": 21}, {"text": ")", "start": 84, "end": 85, "id": 22}, {"text": "Intraoperative", "start": 86, "end": 100, "id": 23}, {"text": "findings", "start": 101, "end": 109, "id": 24}, {"text": "showed", "start": 110, "end": 116, "id": 25}, {"text": "perforation", "start": 117, "end": 128, "id": 26}, {"text": "of", "start": 129, "end": 131, "id": 27}, {"text": "the", "start": 132, "end": 135, "id": 28}, {"text": "cecum", "start": 136, "end": 141, "id": 29}, {"text": "with", "start": 142, "end": 146, "id": 30}, {"text": "no", "start": 147, "end": 149, "id": 31}, {"text": "obvious", "start": 150, "end": 157, "id": 32}, {"text": "masses", "start": 158, "end": 164, "id": 33}, {"text": "(", "start": 165, "end": 166, "id": 34}, {"text": "yellow", "start": 166, "end": 172, "id": 35}, {"text": "arrow", "start": 173, "end": 178, "id": 36}, {"text": ")", "start": 178, "end": 179, "id": 37}, {"text": ".", "start": 179, "end": 180, "id": 38}]}
{"pdf_hash": "2516967c5cfdb7d43d00e2ad449dd7f36f97456d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Preoperative images of a patient with a rectal cancer involving S4 and S5. (A) Axial T1-WI magnetic resonance imaging (MRI) showing invasion of the low sacrum. (B) Axial computed tomography scan demonstrating sacral bone destruction. (C) Sagittal MRI depicting a rectal mass and the sacral segments affected. This image has been used as a scheme to demonstrate the transabdominal route, necessary to gain control of the internal iliac vessels, to dissect the superior and most of the anterior part of the tumor and to do the sacral osteotomy. 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{"pdf_hash": "9142156a5ea9d52c4861fc424e23aa99e362cfe7", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. (A) Preoperative cross-table X-ray. (B) Measurement of anterior femoral head-neck offset. (C) Measurement of the posterior femoral head-neck offset to obtain the relation anterior-posterior femoral head-neck offset. Line 1 follows the femoral neck direction, line 2 is parallel to line 1 and is tangential to the point in which the femoral head loses the anterior sphericity, and line 3 is parallel to 1 and 2 and is tangential to the most anterior point of the femoral head. The distance between line 2 and 3 is what we considered to be the anterior femoral head-neck offset. Line 4 is parallel to the described lines and is tangential to the point in which the femoral head loses the posterior sphericity, and line 5 is tangential to the most posterior point of the femoral head. 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{"pdf_hash": "0fb2cc83386b4369f743004ae5ea76914961c68a", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. Comparison of MRI axial images of the inflammatory area. Different MRI image types 12 hours after bacterial inoculation (ellipse). (A\u2013C) Representative images of a rat which received SPIOlabeled granulocytes. (D\u2013F) Representative images of a rat from the control group which received unlabeled granulocytes. (A, D) T2* weighted images; (B, E) computed susceptibility weighted images (SWI); (C, F) T2-mapping computed images. Maximal loss of signal intensity was detected in T2* weighted images (D). doi:10.1371/journal.pone.0051770.g004", "width": 554, "height": 630, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 64, 65, 66, 67, 68, 26, 27, 60, 61, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 70, 71, 74, 75, 76, 77, 78, 79, 80, 81, 31], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 90, 83, 84, 87, 88, 89, 26, 91, 29, 30, 31], "d": [41, 42, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 63, 64, 65, 66, 67, 68, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107], "e": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 70, 73, 74, 75, 76, 77, 78, 79, 80, 81], "f": [41, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 83, 86, 87, 88, 89, 90, 91]}, "subfigures": [{"id": "2ff0f3d7-d782-45bd-bd26-68b3a5fb58de", "label": "a", "points": [[2, 7], [2, 205], [270, 205], [270, 7]], "color": "yellow"}, {"id": "592e5800-440b-470e-a8fd-f56262ce1e5a", 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{"pdf_hash": "95594ac408c6ea2b9055ed259c4233ba929095dc", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5. Aged SynI\u2013/\u2013 and SynII\u2013/\u2013 mice have an increased neuronal loss in the neocortex. (A) Immunostaining with anti-NeuN antibody of 10-\u03bcm cryostat sections of the somatosensory cortex of aged WT, SynI\u2013/\u2013 and SynII\u2013/\u2013 brains (eight mice per group). Scale bar: 50 \u03bcm. (B) Schematic drawing of a coronal section of mouse brain at bregma level \u20131.55 mm (modified from the Allen Reference Atlas, http://www.brainmap.org/welcome.do), showing the sampled region of the somatosensory cortex that was analyzed (boxed area). (C) The number of NeuN-stained nuclei counted in the sampled area of young and aged mice, plotted as mean percent changes \u00b1 s.e.m. with respect to age-matched WT mice, showed a significant neuronal loss in aged mutant mice. The counts of NeuNstained nuclei/sampled area in WT mice were 946.7\u00b136.5 and 907.6\u00b137.5 for young and aged mice, respectively. Statistical analysis was performed by means of oneway ANOVA [F(2,20) = 12.94, P<0.001] followed by Bonferroni\u2019s multiple comparison test (**P<0.01, ***P<0.001 vs WT).", "width": 1000, "height": 790, "subcaptions": {"a": [105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212]}, "subfigures": [{"id": "a8932ca3-1cd0-48c1-8c5f-a2efd7fb984d", "label": "a", "points": [[2.4, 4.5], [2.4, 413.6], [305.7, 413.6], [305.7, 4.5]], "color": "yellow"}, {"id": "c633bd17-0d5d-497c-a833-bcaf42aea85f", "label": "a", 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{"pdf_hash": "80c5b06ea84b9da3ffc025cb4c9646fed80a3edf", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) The chest radiograph demonstrates diffuse reticulonodular opacities in both lungs. (B) A high resolution computed tomography (HRCT) scan reveals diffuse patchy ground glass opacity (black arrows), mosaic perfusion (black arrowheads) and traction bronchiectasis (white arrows) in both lungs. 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{"pdf_hash": "1498e3d8ec7039b27f36dfbeef4650cb7ac34f7a", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Chest computed tomography angiography of the child showing a minute space between the airway and the spine and the severe ovalization of the stent in the left mainstem bronchus: A) multiplanar coronal reconstruction; B) axial plane.", "width": 944, "height": 554, "subcaptions": {"a": [34, 35, 36, 37, 38], "b": [40, 41, 42, 43]}, "subfigures": [{"id": "758e8a9a-b35c-4b59-898a-23c1d9e186ce", "label": "a", "points": [[4.5, 2.7], [4.5, 548.5], [434, 548.5], [434, 2.7]], "color": "yellow"}, {"id": "ae96e9bb-6dbd-4cc5-ba03-fae314c3fe48", "label": "b", "points": [[463.8, 4.2], [463.8, 551.5], [939.5, 551.5], [939.5, 4.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Chest", "start": 8, "end": 13, "id": 4}, {"text": "computed", "start": 14, "end": 22, "id": 5}, {"text": "tomography", "start": 23, "end": 33, "id": 6}, {"text": "angiography", "start": 34, "end": 45, "id": 7}, {"text": "of", "start": 46, "end": 48, "id": 8}, {"text": "the", "start": 49, "end": 52, "id": 9}, {"text": "child", "start": 53, "end": 58, "id": 10}, {"text": "showing", "start": 59, "end": 66, "id": 11}, {"text": "a", "start": 67, "end": 68, "id": 12}, {"text": "minute", "start": 69, "end": 75, "id": 13}, {"text": "space", "start": 76, "end": 81, "id": 14}, {"text": "between", "start": 82, "end": 89, "id": 15}, {"text": "the", "start": 90, "end": 93, "id": 16}, {"text": "airway", "start": 94, "end": 100, "id": 17}, {"text": "and", "start": 101, "end": 104, "id": 18}, {"text": "the", "start": 105, "end": 108, "id": 19}, {"text": "spine", "start": 109, "end": 114, "id": 20}, {"text": "and", "start": 115, "end": 118, "id": 21}, {"text": "the", "start": 119, "end": 122, "id": 22}, {"text": "severe", "start": 123, "end": 129, "id": 23}, {"text": "ovalization", "start": 130, "end": 141, "id": 24}, {"text": "of", "start": 142, "end": 144, "id": 25}, {"text": "the", "start": 145, "end": 148, "id": 26}, {"text": "stent", "start": 149, "end": 154, "id": 27}, {"text": "in", "start": 155, "end": 157, "id": 28}, {"text": "the", "start": 158, "end": 161, "id": 29}, {"text": "left", "start": 162, "end": 166, "id": 30}, {"text": "mainstem", "start": 167, "end": 175, "id": 31}, {"text": "bronchus", "start": 176, "end": 184, "id": 32}, {"text": ":", "start": 184, "end": 185, "id": 33}, {"text": "A", "start": 186, "end": 187, "id": 34}, {"text": ")", "start": 187, "end": 188, "id": 35}, {"text": "multiplanar", "start": 189, "end": 200, "id": 36}, {"text": "coronal", "start": 201, "end": 208, "id": 37}, {"text": "reconstruction", "start": 209, "end": 223, "id": 38}, {"text": ";", "start": 223, "end": 224, "id": 39}, {"text": "B", "start": 225, "end": 226, "id": 40}, {"text": ")", "start": 226, "end": 227, "id": 41}, {"text": "axial", "start": 228, "end": 233, "id": 42}, {"text": "plane", "start": 234, "end": 239, "id": 43}, {"text": ".", "start": 239, "end": 240, "id": 44}]}
{"pdf_hash": "8b08f9495ed4bc531ef8594f69ead49dc724a783", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2.-Heterogeneous plaque. Transverse (A) and longitudinal (B) 10 MHz high-resolution sonagrams show heterogeneous plaque. Outer vessel wall (large arrows). Markers denote inner vessel wall. Anechoic areas are intermixed within echagenic plaque (small arrows). Presence of calcifications is ignored in this classification and does not place plaque in heterogeneous pattern. C, Corresponding pathologic specimens show subintimal hemorrhage (arrows) .", "width": 978, "height": 958, "subcaptions": {"a": [5, 6, 7, 8, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "b": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "c": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78]}, "subfigures": [{"id": "e7914179-6010-4e3f-8ff6-02071eb0f7df", "label": "a", "points": [[12.6, 25.2], [12.6, 477.9], [474.6, 477.9], [474.6, 25.2]], "color": "yellow"}, {"id": "29d45d7e-854a-4b64-9635-c2ed0f815471", "label": "b", "points": [[487, 26.8], [487, 476.4], [931.9, 476.4], [931.9, 26.8]], "color": "cyan"}, {"id": 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{"pdf_hash": "e022fdaee2b09f111334f08b594d7a37c4745c7b", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. (a) Sagittal T1-weighted magnetic resonance imaging (MRI) prior to surgery showing herniation of the cerebellar tonsils 15 mm below the foramen magnum (black line) into the cervical spinal cord. (b) Sagittal T1-weighted MRI a week after surgery showing slight improvement in the Chiari type 1 malformation. 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{"pdf_hash": "54dc620a9eb9451ba5f02806443ed35a7d595689", "fig_key": "Figure5", "fig_uri": "3-Figure5-1.png", "text": "Fig. 5. (a) Color fundus photograph of left eye post-IMRT showing a regressed lesion marked by reduced elevation of the lesion and resolved subretinal fluid; (b) SD-OCT of the lesion (corresponding line scan to that shown in Fig. 1b) post-IMRT demonstrating resolution of the subretinal fluid and decreased elevation of the lesion; (c) SD-OCT through the macula showing significant reduction in lesion size with corresponding improvement in foveal contour. 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{"pdf_hash": "53852788cc31fd28bf5db8d85a7012ffe5ee0fd9", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Original images from 3-mm slice abdominal CT scans obtained at 31 (a, b) and 32 (c) years of age (before OLT). a Note the multiple calcified stones in the head and body of the pancreas. Arrow indicates superior mesenteric vein. b Arrow indicates markedly atrophic pancreatic parenchyma without calcification in the tail of the gland. c Enhanced image showing atrophic parenchyma in the tail of the gland is more distinguishable (arrow). 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{"pdf_hash": "39de6f85ddefdd33e942b7f73f1bf8ac360cdbb4", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Fig. 2. A 61-year-old woman with newly diagnosed multiple myeloma. A lesion in the body of C7 is detected on whole-body 3T MRI only (arrows). No C7 lesion is detected on (a) whole-body X-ray, (b) FDG-PET/CT, or (c) NaF-PET/CT (circles). The C7 lesion is detected on all four MRI sequences with findings indicative of a myeloma bone lesions (arrows): (d) hypointense on coronal T1W imaging, (e) hyperintense on coronal STIR, (f) high signal intensity on DWI b1000, and (g) low signal intensity on axial ADC. 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{"pdf_hash": "1072d7271033f48164a52eccb2a76832fa7cdde4", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Figure 5. Resection using the magnetic anchor. (a) The mucosa is pulled to create sufficient space to show the line of resection. (b) The resection is performed using an electric knife through an endoscope. (c) The resection line can be clearly shown as a result of traction by the magnetic anchor. (d) The traction of the magnetic anchor is sufficient to allow the mucosal flap to be turned over. 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{"pdf_hash": "e1222a1f7b873737e8e3639d0b2d9ec05e7d823c", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 Case 4: T1 (A) and T2 (B) weighted spin echo axial magnetic resonance imaging at presentation, and T2 sequences at three months after presentation (C and D). Nodules of silicone are seen (large arrows), as are less well defined foci (arrowheads). Note that on the T2 sequences (and on short tau inversion recovery sequences [not pictured]), both the oedematous surrounding fat and the silicone, as well as the testes (asterisks), are of high signal, the silicone being most intense. On the T1 sequence, all of these components are of intermediate signal. However, a chemical shift artefact (seen best around the nodule indicated by the large arrows) is produced by the different resonant frequencies of the silicone and oedematous fat, resulting in an artefactually bright left border and dark right border to the silicone. At three months, most of the large lobules of silicone have been removed or have diffused but several small nodules are still visible (large arrows). 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{"pdf_hash": "5b898506e23d072d0b61243baf364d4e199c21df", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. A: Chest radiograph at initial presentation. The presence of a large right pneumothorax is identified (arrows). B: Axial image from the patient\u2019s chest computed tomography at presentation. Two cavitary lesions consistent with his Aspergillus pneumonia are present within the right lung parenchyma.", "width": 954, "height": 416, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "f4269bb8-b03a-46bd-98da-e6f3b7426765", "label": "a", "points": [[30.4, 6.5], [30.4, 386.3], [456.9, 386.3], [456.9, 6.5]], "color": "yellow"}, {"id": "95e9791b-4288-4172-bd52-cce076274c7e", "label": "b", "points": [[470.5, 6.5], [470.5, 392.4], [940.7, 392.4], [940.7, 6.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": ":", "start": 9, "end": 10, "id": 5}, {"text": "Chest", "start": 11, "end": 16, "id": 6}, {"text": "radiograph", "start": 17, "end": 27, "id": 7}, {"text": "at", "start": 28, "end": 30, "id": 8}, {"text": "initial", "start": 31, "end": 38, "id": 9}, {"text": "presentation", "start": 39, "end": 51, "id": 10}, {"text": ".", "start": 51, "end": 52, "id": 11}, {"text": "The", "start": 53, "end": 56, "id": 12}, {"text": "presence", "start": 57, "end": 65, "id": 13}, {"text": "of", "start": 66, "end": 68, "id": 14}, {"text": "a", "start": 69, "end": 70, "id": 15}, {"text": "large", "start": 71, "end": 76, "id": 16}, {"text": "right", "start": 77, "end": 82, "id": 17}, {"text": "pneumothorax", "start": 83, "end": 95, "id": 18}, {"text": "is", "start": 96, "end": 98, "id": 19}, {"text": "identified", "start": 99, "end": 109, "id": 20}, {"text": "(", "start": 110, "end": 111, "id": 21}, {"text": "arrows", "start": 111, "end": 117, "id": 22}, {"text": ")", "start": 117, "end": 118, "id": 23}, {"text": ".", "start": 118, "end": 119, "id": 24}, {"text": "B", "start": 120, "end": 121, "id": 25}, {"text": ":", "start": 121, "end": 122, "id": 26}, {"text": "Axial", "start": 123, "end": 128, "id": 27}, {"text": "image", "start": 129, "end": 134, "id": 28}, {"text": "from", "start": 135, "end": 139, "id": 29}, {"text": "the", "start": 140, "end": 143, "id": 30}, {"text": "patient", "start": 144, "end": 151, "id": 31}, {"text": "\u2019s", "start": 151, "end": 153, "id": 32}, {"text": "chest", "start": 154, "end": 159, "id": 33}, {"text": "computed", "start": 160, "end": 168, "id": 34}, {"text": "tomography", "start": 169, "end": 179, "id": 35}, {"text": "at", "start": 180, "end": 182, "id": 36}, {"text": "presentation", "start": 183, "end": 195, "id": 37}, {"text": ".", "start": 195, "end": 196, "id": 38}, {"text": "Two", "start": 197, "end": 200, "id": 39}, {"text": "cavitary", "start": 201, "end": 209, "id": 40}, {"text": "lesions", "start": 210, "end": 217, "id": 41}, {"text": "consistent", "start": 218, "end": 228, "id": 42}, {"text": "with", "start": 229, "end": 233, "id": 43}, {"text": "his", "start": 234, "end": 237, "id": 44}, {"text": "Aspergillus", "start": 238, "end": 249, "id": 45}, {"text": "pneumonia", "start": 250, "end": 259, "id": 46}, {"text": "are", "start": 260, "end": 263, "id": 47}, {"text": "present", "start": 264, "end": 271, "id": 48}, {"text": "within", "start": 272, "end": 278, "id": 49}, {"text": "the", "start": 279, "end": 282, "id": 50}, {"text": "right", "start": 283, "end": 288, "id": 51}, {"text": "lung", "start": 289, "end": 293, "id": 52}, {"text": "parenchyma", "start": 294, "end": 304, "id": 53}, {"text": ".", "start": 304, "end": 305, "id": 54}]}
{"pdf_hash": "06c044f0abedac43e5ab58383fc89d466aed247b", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 (A) Apical-long-axis view, angled posteriorly showing the extent of tumour. (B) Subcostal coronal view showing the tumour and small pericardial effusion. (C ) Parasternal short axis view showing the septal involvement and lack of line of demarcation between normal myocardium and tumour. LA, left atrium; LV, left ventricle; RV, right ventricle.", "width": 666, "height": 736, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "c": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "4be0e056-ce7b-4442-9227-37b0ffb55d3e", "label": "a", "points": [[12.1, 0.9], [12.1, 364.9], [348.8, 364.9], [348.8, 0.9]], "color": "yellow"}, {"id": "cec5f0b5-1125-45d3-b3fb-2b3c423afd64", "label": "b", "points": [[353, 1.9], [353, 366], [656, 366], [656, 1.9]], "color": "cyan"}, {"id": "beb79abe-b0c0-4d3d-b3fe-9ad864303bfd", "label": "c", "points": [[7.9, 371.2], [7.9, 698.4], [656, 698.4], [656, 371.2]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Apical", "start": 13, "end": 19, "id": 5}, {"text": "-", "start": 19, "end": 20, "id": 6}, {"text": "long", "start": 20, "end": 24, "id": 7}, {"text": "-", "start": 24, "end": 25, "id": 8}, {"text": "axis", "start": 25, "end": 29, "id": 9}, {"text": "view", "start": 30, "end": 34, "id": 10}, {"text": ",", "start": 34, "end": 35, "id": 11}, {"text": "angled", "start": 36, "end": 42, "id": 12}, {"text": "posteriorly", "start": 43, "end": 54, "id": 13}, {"text": "showing", "start": 55, "end": 62, "id": 14}, {"text": "the", "start": 63, "end": 66, "id": 15}, {"text": "extent", "start": 67, "end": 73, "id": 16}, {"text": "of", "start": 74, "end": 76, "id": 17}, {"text": "tumour", "start": 77, "end": 83, "id": 18}, {"text": ".", "start": 83, "end": 84, "id": 19}, {"text": "(", "start": 85, "end": 86, "id": 20}, {"text": "B", "start": 86, "end": 87, "id": 21}, {"text": ")", "start": 87, "end": 88, "id": 22}, {"text": "Subcostal", "start": 89, "end": 98, "id": 23}, {"text": "coronal", "start": 99, "end": 106, "id": 24}, {"text": "view", "start": 107, "end": 111, "id": 25}, {"text": "showing", "start": 112, "end": 119, "id": 26}, {"text": "the", "start": 120, "end": 123, "id": 27}, {"text": "tumour", "start": 124, "end": 130, "id": 28}, {"text": "and", "start": 131, "end": 134, "id": 29}, {"text": "small", "start": 135, "end": 140, "id": 30}, {"text": "pericardial", "start": 141, "end": 152, "id": 31}, {"text": "effusion", "start": 153, "end": 161, "id": 32}, {"text": ".", "start": 161, "end": 162, "id": 33}, {"text": "(", "start": 163, "end": 164, "id": 34}, {"text": "C", "start": 164, "end": 165, "id": 35}, {"text": ")", "start": 166, "end": 167, "id": 36}, {"text": "Parasternal", "start": 168, "end": 179, "id": 37}, {"text": "short", "start": 180, "end": 185, "id": 38}, {"text": "axis", "start": 186, "end": 190, "id": 39}, {"text": "view", "start": 191, "end": 195, "id": 40}, {"text": "showing", "start": 196, "end": 203, "id": 41}, {"text": "the", "start": 204, "end": 207, "id": 42}, {"text": "septal", "start": 208, "end": 214, "id": 43}, {"text": "involvement", "start": 215, "end": 226, "id": 44}, {"text": "and", "start": 227, "end": 230, "id": 45}, {"text": "lack", "start": 231, "end": 235, "id": 46}, {"text": "of", "start": 236, "end": 238, "id": 47}, {"text": "line", "start": 239, "end": 243, "id": 48}, {"text": "of", "start": 244, "end": 246, "id": 49}, {"text": "demarcation", "start": 247, "end": 258, "id": 50}, {"text": "between", "start": 259, "end": 266, "id": 51}, {"text": "normal", "start": 267, "end": 273, "id": 52}, {"text": "myocardium", "start": 274, "end": 284, "id": 53}, {"text": "and", "start": 285, "end": 288, "id": 54}, {"text": "tumour", "start": 289, "end": 295, "id": 55}, {"text": ".", "start": 295, "end": 296, "id": 56}, {"text": "LA", "start": 297, "end": 299, "id": 57}, {"text": ",", "start": 299, "end": 300, "id": 58}, {"text": "left", "start": 301, "end": 305, "id": 59}, {"text": "atrium", "start": 306, "end": 312, "id": 60}, {"text": ";", "start": 312, "end": 313, "id": 61}, {"text": "LV", "start": 314, "end": 316, "id": 62}, {"text": ",", "start": 316, "end": 317, "id": 63}, {"text": "left", "start": 318, "end": 322, "id": 64}, {"text": "ventricle", "start": 323, "end": 332, "id": 65}, {"text": ";", "start": 332, "end": 333, "id": 66}, {"text": "RV", "start": 334, "end": 336, "id": 67}, {"text": ",", "start": 336, "end": 337, "id": 68}, {"text": "right", "start": 338, "end": 343, "id": 69}, {"text": "ventricle", "start": 344, "end": 353, "id": 70}, {"text": ".", "start": 353, "end": 354, "id": 71}]}
{"pdf_hash": "2439e8cda594beee4051788e8f3358e45c49d579", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Fig. 3. Grades of pancreatic intraepithelial neoplasia (PanIN). (A) A duct involved by PanIN2 shows pseudostratification of nuclei with mild to mo derate cytologic abnormalities. (B) In PanIN3, budding of cellular tufts into the duct lumen and moderate to severe nuclear atypia are noted.", "width": 1324, "height": 474, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "9affefbb-709f-4581-90ca-15fc73f0d1b9", "label": "a", "points": [[9.5, 5.9], [9.5, 468.2], [660, 468.2], [660, 5.9]], "color": "yellow"}, {"id": "9b91449c-d6f6-43b2-855c-156962751848", "label": "b", "points": [[668.4, 10.1], [668.4, 472.4], [1318.9, 472.4], [1318.9, 10.1]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Grades", "start": 8, "end": 14, "id": 4}, {"text": "of", "start": 15, "end": 17, "id": 5}, {"text": "pancreatic", "start": 18, "end": 28, "id": 6}, {"text": "intraepithelial", "start": 29, "end": 44, "id": 7}, {"text": "neoplasia", "start": 45, "end": 54, "id": 8}, {"text": "(", "start": 55, "end": 56, "id": 9}, {"text": "PanIN", "start": 56, "end": 61, "id": 10}, {"text": ")", "start": 61, "end": 62, "id": 11}, {"text": ".", "start": 62, "end": 63, "id": 12}, {"text": "(", "start": 64, "end": 65, "id": 13}, {"text": "A", "start": 65, "end": 66, "id": 14}, {"text": ")", "start": 66, "end": 67, "id": 15}, {"text": "A", "start": 68, "end": 69, "id": 16}, {"text": "duct", "start": 70, "end": 74, "id": 17}, {"text": "involved", "start": 75, "end": 83, "id": 18}, {"text": "by", "start": 84, "end": 86, "id": 19}, {"text": "PanIN2", "start": 87, "end": 93, "id": 20}, {"text": "shows", "start": 94, "end": 99, "id": 21}, {"text": "pseudostratification", "start": 100, "end": 120, "id": 22}, {"text": "of", "start": 121, "end": 123, "id": 23}, {"text": "nuclei", "start": 124, "end": 130, "id": 24}, {"text": "with", "start": 131, "end": 135, "id": 25}, {"text": "mild", "start": 136, "end": 140, "id": 26}, {"text": "to", "start": 141, "end": 143, "id": 27}, {"text": "mo", "start": 144, "end": 146, "id": 28}, {"text": "derate", "start": 147, "end": 153, "id": 29}, {"text": "cytologic", "start": 154, "end": 163, "id": 30}, {"text": "abnormalities", "start": 164, "end": 177, "id": 31}, {"text": ".", "start": 177, "end": 178, "id": 32}, {"text": "(", "start": 179, "end": 180, "id": 33}, {"text": "B", "start": 180, "end": 181, "id": 34}, {"text": ")", "start": 181, "end": 182, "id": 35}, {"text": "In", "start": 183, "end": 185, "id": 36}, {"text": "PanIN3", "start": 186, "end": 192, "id": 37}, {"text": ",", "start": 192, "end": 193, "id": 38}, {"text": "budding", "start": 194, "end": 201, "id": 39}, {"text": "of", "start": 202, "end": 204, "id": 40}, {"text": "cellular", "start": 205, "end": 213, "id": 41}, {"text": "tufts", "start": 214, "end": 219, "id": 42}, {"text": "into", "start": 220, "end": 224, "id": 43}, {"text": "the", "start": 225, "end": 228, "id": 44}, {"text": "duct", "start": 229, "end": 233, "id": 45}, {"text": "lumen", "start": 234, "end": 239, "id": 46}, {"text": "and", "start": 240, "end": 243, "id": 47}, {"text": "moderate", "start": 244, "end": 252, "id": 48}, {"text": "to", "start": 253, "end": 255, "id": 49}, {"text": "severe", "start": 256, "end": 262, "id": 50}, {"text": "nuclear", "start": 263, "end": 270, "id": 51}, {"text": "atypia", "start": 271, "end": 277, "id": 52}, {"text": "are", "start": 278, "end": 281, "id": 53}, {"text": "noted", "start": 282, "end": 287, "id": 54}, {"text": ".", "start": 287, "end": 288, "id": 55}]}
{"pdf_hash": "5960bfefe3422c7cc15db81cd3c7e64d5d96202f", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3: Case 1 \u2013 CBCT. Axial image (a). Sagittal reformatted images (2 adjacent slices) (b). Note an expansile radiolucent lesion at the dorsal phalangeal cortex with sclerotic borders (arrows in a). The smaller intramedullary and a larger exophytic components of the lesion are clearly depicted. The cortex is thinned and partially destructed with overhanging edges (arrowheads in b).", "width": 1068, "height": 504, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "b": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75]}, "subfigures": [{"id": "fb405de9-9af4-48e6-aef3-7752c3eb4373", "label": "a", "points": [[1.7, 0], [1.7, 479.2], [551.7, 479.2], [551.7, 0]], "color": "yellow"}, {"id": "d669e5f5-ac49-4b63-9d98-2c73eb1a6b8d", "label": "b", "points": [[560.2, 479.2], [560.2, 5.1], [1062.9, 5.1], [1062.9, 479.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Case", "start": 10, "end": 14, "id": 3}, {"text": "1", "start": 15, "end": 16, "id": 4}, {"text": "\u2013", "start": 17, "end": 18, "id": 5}, {"text": "CBCT", "start": 19, "end": 23, "id": 6}, {"text": ".", "start": 23, "end": 24, "id": 7}, {"text": "Axial", "start": 25, "end": 30, "id": 8}, {"text": "image", "start": 31, "end": 36, "id": 9}, {"text": "(", "start": 37, "end": 38, "id": 10}, {"text": "a", "start": 38, "end": 39, "id": 11}, {"text": ")", "start": 39, "end": 40, "id": 12}, {"text": ".", "start": 40, "end": 41, "id": 13}, {"text": "Sagittal", "start": 42, "end": 50, "id": 14}, {"text": "reformatted", "start": 51, "end": 62, "id": 15}, {"text": "images", "start": 63, "end": 69, "id": 16}, {"text": "(", "start": 70, "end": 71, "id": 17}, {"text": "2", "start": 71, "end": 72, "id": 18}, {"text": "adjacent", "start": 73, "end": 81, "id": 19}, {"text": "slices", "start": 82, "end": 88, "id": 20}, {"text": ")", "start": 88, "end": 89, "id": 21}, {"text": "(", "start": 90, "end": 91, "id": 22}, {"text": "b", "start": 91, "end": 92, "id": 23}, {"text": ")", "start": 92, "end": 93, "id": 24}, {"text": ".", "start": 93, "end": 94, "id": 25}, {"text": "Note", "start": 95, "end": 99, "id": 26}, {"text": "an", "start": 100, "end": 102, "id": 27}, {"text": "expansile", "start": 103, "end": 112, "id": 28}, {"text": "radiolucent", "start": 113, "end": 124, "id": 29}, {"text": "lesion", "start": 125, "end": 131, "id": 30}, {"text": "at", "start": 132, "end": 134, "id": 31}, {"text": "the", "start": 135, "end": 138, "id": 32}, {"text": "dorsal", "start": 139, "end": 145, "id": 33}, {"text": "phalangeal", "start": 146, "end": 156, "id": 34}, {"text": "cortex", "start": 157, "end": 163, "id": 35}, {"text": "with", "start": 164, "end": 168, "id": 36}, {"text": "sclerotic", "start": 169, "end": 178, "id": 37}, {"text": "borders", "start": 179, "end": 186, "id": 38}, {"text": "(", "start": 187, "end": 188, "id": 39}, {"text": "arrows", "start": 188, "end": 194, "id": 40}, {"text": "in", "start": 195, "end": 197, "id": 41}, {"text": "a", "start": 198, "end": 199, "id": 42}, {"text": ")", "start": 199, "end": 200, "id": 43}, {"text": ".", "start": 200, "end": 201, "id": 44}, {"text": "The", "start": 202, "end": 205, "id": 45}, {"text": "smaller", "start": 206, "end": 213, "id": 46}, {"text": "intramedullary", "start": 214, "end": 228, "id": 47}, {"text": "and", "start": 229, "end": 232, "id": 48}, {"text": "a", "start": 233, "end": 234, "id": 49}, {"text": "larger", "start": 235, "end": 241, "id": 50}, {"text": "exophytic", "start": 242, "end": 251, "id": 51}, {"text": "components", "start": 252, "end": 262, "id": 52}, {"text": "of", "start": 263, "end": 265, "id": 53}, {"text": "the", "start": 266, "end": 269, "id": 54}, {"text": "lesion", "start": 270, "end": 276, "id": 55}, {"text": "are", "start": 277, "end": 280, "id": 56}, {"text": "clearly", "start": 281, "end": 288, "id": 57}, {"text": "depicted", "start": 289, "end": 297, "id": 58}, {"text": ".", "start": 297, "end": 298, "id": 59}, {"text": "The", "start": 299, "end": 302, "id": 60}, {"text": "cortex", "start": 303, "end": 309, "id": 61}, {"text": "is", "start": 310, "end": 312, "id": 62}, {"text": "thinned", "start": 313, "end": 320, "id": 63}, {"text": "and", "start": 321, "end": 324, "id": 64}, {"text": "partially", "start": 325, "end": 334, "id": 65}, {"text": "destructed", "start": 335, "end": 345, "id": 66}, {"text": "with", "start": 346, "end": 350, "id": 67}, {"text": "overhanging", "start": 351, "end": 362, "id": 68}, {"text": "edges", "start": 363, "end": 368, "id": 69}, {"text": "(", "start": 369, "end": 370, "id": 70}, {"text": "arrowheads", "start": 370, "end": 380, "id": 71}, {"text": "in", "start": 381, "end": 383, "id": 72}, {"text": "b", "start": 384, "end": 385, "id": 73}, {"text": ")", "start": 385, "end": 386, "id": 74}, {"text": ".", "start": 386, "end": 387, "id": 75}]}
{"pdf_hash": "b264f3237cd97981586ec7cb435e8bf154cbcc44", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Malignant transformation to HCC. HCCs of small (0.2-0.5 cm) (A,A 0 ), intermediate (B), or large (>2.5 cm) (C) size. Scale bar 5 1 cm. Histology of livers containing premalignant nodules (D) or mHCC tissue (E,F). Scale bars 5 (D,E) 100 lm, (F) 50 lm. Hyperproliferative nodules are composed of small, basophilic hepatocytes showing a microtrabecular growth (D, left), express the SRF target gene Egr1 (D, middle), and the polarization marker DPP IV (D, right). HCC tissue characterized by nuclear and architectural atypia in the form of pseudoglandular (black arrowhead) and irregular solid-trabecular growth patterns (red arrowhead) (E, left; F, left). 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{"pdf_hash": "c4ce18a8485bc52db4269365dfe81f6cdde32244", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "FIGURE 2. Total summed images (02120 min) of 11 C-dLop at baseline (A) and after P-gp blockade (B). At baseline, all regions of brain except pituitary (A, arrow) had low uptake. (C) MR image coregistered with P-gpblocked image of same monkey. 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{"pdf_hash": "ce1aea090fe754ee27e893869e2100cfffdafea0", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Primary tumor and pulmonary embolism. a Coronal chest MRI of a 36-year-old female with a recurrent right upper extremity myxofibrosarcoma. b Chest computed tomography of pulmonary artery saddle embolism (arrow)", "width": 652, "height": 838, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [32, 33, 34, 35, 36, 37, 38, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "acdcbe84-c0cd-4f9a-8630-e851b0a0d935", "label": "a", "points": [[30, 17.9], [30, 405.1], [621.3, 405.1], [621.3, 17.9]], "color": "yellow"}, {"id": "26357d03-f03e-4e1d-b87b-b556623a4a26", "label": "b", "points": [[29, 425.4], [29, 806.5], [621.3, 806.5], [621.3, 425.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Primary", "start": 7, "end": 14, "id": 3}, {"text": "tumor", "start": 15, "end": 20, "id": 4}, {"text": "and", "start": 21, "end": 24, "id": 5}, {"text": "pulmonary", "start": 25, "end": 34, "id": 6}, {"text": "embolism", "start": 35, "end": 43, "id": 7}, {"text": ".", "start": 43, "end": 44, "id": 8}, {"text": "a", "start": 45, "end": 46, "id": 9}, {"text": "Coronal", "start": 47, "end": 54, "id": 10}, {"text": "chest", "start": 55, "end": 60, "id": 11}, {"text": "MRI", "start": 61, "end": 64, "id": 12}, {"text": "of", "start": 65, "end": 67, "id": 13}, {"text": "a", "start": 68, "end": 69, "id": 14}, {"text": "36-year", "start": 70, "end": 77, "id": 15}, {"text": "-", "start": 77, "end": 78, "id": 16}, {"text": "old", "start": 78, "end": 81, "id": 17}, {"text": "female", "start": 82, "end": 88, "id": 18}, {"text": "with", "start": 89, "end": 93, "id": 19}, {"text": "a", "start": 94, "end": 95, "id": 20}, {"text": "recurrent", "start": 96, "end": 105, "id": 21}, {"text": "right", "start": 106, "end": 111, "id": 22}, {"text": "upper", "start": 112, "end": 117, "id": 23}, {"text": "extremity", "start": 118, "end": 127, "id": 24}, {"text": "myxofibrosarcoma", "start": 128, "end": 144, "id": 25}, {"text": ".", "start": 144, "end": 145, "id": 26}, {"text": "b", "start": 146, "end": 147, "id": 27}, {"text": "Chest", "start": 148, "end": 153, "id": 28}, {"text": "computed", "start": 154, "end": 162, "id": 29}, {"text": "tomography", "start": 163, "end": 173, "id": 30}, {"text": "of", "start": 174, "end": 176, "id": 31}, {"text": "pulmonary", "start": 177, "end": 186, "id": 32}, {"text": "artery", "start": 187, "end": 193, "id": 33}, {"text": "saddle", "start": 194, "end": 200, "id": 34}, {"text": "embolism", "start": 201, "end": 209, "id": 35}, {"text": "(", "start": 210, "end": 211, "id": 36}, {"text": "arrow", "start": 211, "end": 216, "id": 37}, {"text": ")", "start": 216, "end": 217, "id": 38}]}
{"pdf_hash": "9e92dbddaf3594888e2519105bb7fe3384c07d62", "fig_key": "Figure5", "fig_uri": "21-Figure5-1.png", "text": "Fig. 5. Micro-CT images showing a transverse section of the osteochondral defect in a medial femoral condyle (A), sections of a 6 week Both sample in the cortical (B) and trabecular (C) region, and sections of a 12 week BMP-2 sample in the cortical (D) and trabecular (E) region. (A) also demonstrates the two volumes of interest used, cartilage and cortical (C&C) and trabecular, when analyzing the subchondral bone. 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{"pdf_hash": "038546960b3677dc6249a904cd10e1deca5f4005", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Computed tomography features and histological characteristics of perivascular epithelioid cell tumors in the lung. (a, b) Contrast-enhanced computed tomography thorax-axial and coronal section showing a mass in the right lower lobe. (c) Gross pathological examination shows a mass >4 cm. (d) The tumor does not have a fibrous capsule and presents with a solid cellular growth pattern. (e) Abundant stroma with thin walled blood vessels. (f) The tumor is predominantly composed of spindle and histiocytoid shaped cells. (g) Perivascular epithelial cells are arranged around the vessels. (h) Hyaline degeneration. 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{"pdf_hash": "39c29468175302420af63583f68bbb17fa0b81eb", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Scan images of a 67-year-old male patient with pretreated adenocarcinoma (39x23 mm) in the right middle lobe of the lung. An 18 F-FLT PET/CT scan was performed 3 days after an 18 F-FDG scan. (A) 18 F-FDG PET/CT scan image. (B) 18 F-FLT PET/CT scan image. (C) CT scan providing additional anatomical information. (D) Enlarged 18 F-FDG scan image of the area indicated by the arrow. (E) Enlarged 18 F-FLT scan image of the area indicated by the arrow. (F) Hematoxylin and eosin staining indicated lung adenocarcinoma. 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{"pdf_hash": "08e28d95c229b97fecd3f41dc39643f648094ee9", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 (A) Immunostaining of normal lung parenchyma and lung cancer tissue on paraffin-embedded sections using an antiSkp2 monoclonal antibody (2C8D9, Zymed). (a) Absence of immunostaining in the columnar epithelium lining a normal bronchial structure (o1% of positive cells). (b) Negative immunostaining (class 0) in a typical carcinoid. (c and d) Strong positive nuclear immunostaining (class 2) on (c) most or (d) 50% of tumor cells in SCLCs. (e) Weak nuclear immunostaining (class 1) in a squamous cell carcinoma. (f) Negative immunostaining (class 0) in an adenocarcinoma. 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{"pdf_hash": "a5699cd3abf0bb183a4db58b8819cc9a840c7201", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Changes in nuclear (A-E) and dense granule (F-J) morphology of C. parvum sporozoites following gamma irradiation. (A, F) non-irradiated control; (B, G) 1 kGy; (C, H) 5 kGy; (D, I) 10 kGy; (E, J) 25 kGy. Bar = 0.2 \u03bcm. Asterisk in A; plastid-like organelle. 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{"pdf_hash": "9a8187021e5414dd0db438a25567ba32bcaee3ce", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. Tooth morphology of thymosin \u03b2 \u03b2 \u03b2 \u03b2 \u03b24 over-expressing mice. The teeth of the transgenic mice were blunter due to significant fragility and they appeared chalky in color, indicating enamel hypoplasia (A,B). 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{"pdf_hash": "386f2ecdd510a5beef89d69c1034efa710013b43", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5. Detection of phosphorylated SMAD1/5/8 proteins (pSMAD) on tissue sections. The brown precipitate reveals pSMAD-positive nuclei. All sections are counterstained with Hoechst 33258 (light blue fluorescence) to reveal nuclei lacking pSMADs. All sections are sagittal along the primary embryonic axis with ventral to the left and dorsal to the right. Sections shown are representative of the results obtained by analysing serial sections of at least three embryos per genotype. (A,C,E) Wild-type mouse embryos at E11.0 (40 somites; A); E11.25 (47 somites; C) and E11.5 (50 somites, enlargement of tip region; E). (B,D,F) Grem1-deficient embryos at E11.0 (42 somites; B) and E11.25 (48 somites; D), an enlargement of the ureteric bud area in D is shown in F. The area within the red dashed line contains many picnotic nuclei indicative of the onset of cellular apoptosis (D,F). cm, condensing metanephric mesenchyme; mm, metanephric mesenchyme; sm, stromal mesenchyme; ub, ureteric bud; ue, ureteric epithelium (first branch); us, ureteric stalk; wd, Wolffian duct.", "width": 792, "height": 622, "subcaptions": {"a": [96, 97, 98, 99, 100, 101, 102, 83, 84, 89, 90, 91, 92, 93, 94, 95], "b": [131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 125, 126], "c": [104, 105, 106, 107, 108, 109, 110, 83, 86, 89, 90, 91, 92, 93, 94, 95], "d": [128, 131, 132, 133, 134, 143, 144, 145, 146, 147, 148, 149, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 186, 187, 125], "e": [83, 88, 89, 90, 91, 92, 93, 94, 95, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123], "f": [130, 131, 132, 133, 134, 143, 144, 145, 146, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 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{"pdf_hash": "0451dbe4dcb1eff17e5ee08b5e944a9c9b7642eb", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1: 87 year old male with Crowned Dens Syndrome. Axial images of the cervical spine at the level of the dens, in bone (a) and soft tissue (b) windows, demonstrate erosion and posterior remodeling of the dens (dashed arrows) with a peripherally calcified soft tissue mass in a \"halo or crown-like\" appearance (solid arrows). Protocol: Siemens CT, mAs 376, KV 120, 3 mm slice thickness, without contrast.", "width": 1450, "height": 704, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71]}, "subfigures": [{"id": "c9b6f21b-ea29-4c71-8341-76c617cf7b92", "label": "a", "points": [[28.7, 50], [28.7, 689.1], [686.1, 689.1], [686.1, 50]], "color": "yellow"}, {"id": "c23effec-907b-4b6f-9667-ea32aa1f4da9", "label": "b", "points": [[704.5, 40.9], [704.5, 691.4], [1423.7, 691.4], [1423.7, 40.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, 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{"pdf_hash": "6e1e4152fee077a6a789f6db8b00ea62ba34da30", "fig_key": "Figure7", "fig_uri": "6-Figure7-1.png", "text": "Fig. 7. Endoscopic views of the extent of sellar opening. The sellar floor is opened from cavernous sinus to cavernous sinus and from the planum sphenoidale to the clivus. A small ledge of bone is left intact bilaterally. This allows a graft to be placed at the end of the operation to reconstruct the sellar floor. Left: Example of a sellar opening prior to resection of an intrasellar microadenoma. Note the excellent view of the intrasphenoidal anatomy. Right: Example of the sellar opening prior to resection of a macroadenoma with suprasellar extension. Note the disruption of the normal sphenoidal anatomy. PG = pituitary gland.", "width": 1400, "height": 550, "subcaptions": {"a": [62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85], "b": [86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111]}, "subfigures": [{"id": "55e39a11-0820-4dcd-bb76-190b8a8b2226", "label": "a", "points": [[4.4, 4.4], [4.4, 515.3], [707.8, 515.3], [707.8, 4.4]], "color": "yellow"}, {"id": "531156e5-13d4-485b-85e3-a442fffd73bf", "label": "b", "points": [[725.5, 6.6], [725.5, 517.5], [1395.6, 517.5], [1395.6, 6.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "7", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Endoscopic", "start": 8, "end": 18, "id": 4}, {"text": "views", "start": 19, "end": 24, "id": 5}, {"text": "of", "start": 25, "end": 27, "id": 6}, {"text": "the", "start": 28, 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{"pdf_hash": "cbe5236ff6193cafd3fa8073d1671fddbfff4079", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Fig. 1. (A) Cervical T2-weighted magnetic resonance imaging (MRI) showed serpentine vascular signal void (white arrow) at the C1-T1 region and diffuse edema in the spinal cord at C1-C4. (B) Abnormal perimedullary vascular enhancement (white arrow) noted on contrast enhanced MRI.", "width": 684, "height": 558, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "85dae546-29e0-4ea0-bc5a-5425d1d77a0e", "label": "a", "points": [[39.1, 2.5], [39.1, 523.4], [355.7, 523.4], [355.7, 2.5]], "color": "yellow"}, {"id": "f136be60-514a-47ac-94c4-239668dcd19f", "label": "b", "points": [[370.8, 4.7], [370.8, 525.5], [683.1, 525.5], [683.1, 4.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Cervical", "start": 12, "end": 20, "id": 7}, {"text": "T2-weighted", "start": 21, "end": 32, "id": 8}, {"text": "magnetic", "start": 33, "end": 41, "id": 9}, {"text": "resonance", "start": 42, "end": 51, "id": 10}, {"text": "imaging", "start": 52, "end": 59, "id": 11}, {"text": "(", "start": 60, "end": 61, "id": 12}, {"text": "MRI", "start": 61, "end": 64, "id": 13}, {"text": ")", "start": 64, "end": 65, "id": 14}, {"text": "showed", "start": 66, "end": 72, "id": 15}, {"text": "serpentine", "start": 73, "end": 83, "id": 16}, {"text": "vascular", "start": 84, "end": 92, "id": 17}, {"text": "signal", "start": 93, "end": 99, "id": 18}, {"text": "void", "start": 100, "end": 104, "id": 19}, {"text": "(", "start": 105, "end": 106, "id": 20}, {"text": "white", "start": 106, "end": 111, "id": 21}, {"text": "arrow", "start": 112, "end": 117, "id": 22}, {"text": ")", "start": 117, "end": 118, "id": 23}, {"text": "at", "start": 119, "end": 121, "id": 24}, {"text": "the", "start": 122, "end": 125, "id": 25}, {"text": "C1-T1", "start": 126, "end": 131, "id": 26}, {"text": "region", "start": 132, "end": 138, "id": 27}, {"text": "and", "start": 139, "end": 142, "id": 28}, {"text": "diffuse", "start": 143, "end": 150, "id": 29}, {"text": "edema", "start": 151, "end": 156, "id": 30}, {"text": "in", "start": 157, "end": 159, "id": 31}, {"text": "the", "start": 160, "end": 163, "id": 32}, {"text": "spinal", "start": 164, "end": 170, "id": 33}, {"text": "cord", "start": 171, "end": 175, "id": 34}, {"text": "at", "start": 176, "end": 178, "id": 35}, {"text": "C1-C4", "start": 179, "end": 184, "id": 36}, {"text": ".", "start": 184, "end": 185, "id": 37}, {"text": "(", "start": 186, "end": 187, "id": 38}, {"text": "B", "start": 187, "end": 188, "id": 39}, {"text": ")", "start": 188, "end": 189, "id": 40}, {"text": "Abnormal", "start": 190, "end": 198, "id": 41}, {"text": "perimedullary", "start": 199, "end": 212, "id": 42}, {"text": "vascular", "start": 213, "end": 221, "id": 43}, {"text": "enhancement", "start": 222, "end": 233, "id": 44}, {"text": "(", "start": 234, "end": 235, "id": 45}, {"text": "white", "start": 235, "end": 240, "id": 46}, {"text": "arrow", "start": 241, "end": 246, "id": 47}, {"text": ")", "start": 246, "end": 247, "id": 48}, {"text": "noted", "start": 248, "end": 253, "id": 49}, {"text": "on", "start": 254, "end": 256, "id": 50}, {"text": "contrast", "start": 257, "end": 265, "id": 51}, {"text": "enhanced", "start": 266, "end": 274, "id": 52}, {"text": "MRI", "start": 275, "end": 278, "id": 53}, {"text": ".", "start": 278, "end": 279, "id": 54}]}
{"pdf_hash": "d748c9bad3ae3e6d15cbd2d9c8526d374beb9f9a", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "FIG. 2. a-d. 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{"pdf_hash": "60c3a6fef6bcf8d11b2bcfe730241a1bd1c6436e", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Examination results on admission. (a) Positron emission tomography-computed tomography (PET)-CT scan showing a right superior lobe mass and metastases in mediastinal nodal stations. (b) Bronchoscopy demonstrating luminal narrowing of the upper bronchus of the right upper lobe. (c) PET-CT scan showing multiple metastases in the bilateral lung. (d) Magnetic resonance imaging demonstrating metastases in the pelvic bone. (e) Bronchoscopic biopsy specimen showing adenocarcinoma. 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{"pdf_hash": "f3050360e919c190c4b73f61d2761c7328496c76", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "FIGURE 3 Human skin morphology. Optical coronal sections of adult skin sample stained with CG5N allow us to identify different strata of the epidermis in living samples. (A) 0 mm, stratum corneum. (B) 40 mm, stratum granulosum. (C) 60 mm, stratum spinosum. (D) 80 mm, stratum basale. 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{"pdf_hash": "ef2bab6cbbab35c34b9ae136e42ff1a8532f697b", "fig_key": "Figure7", "fig_uri": "9-Figure7-1.png", "text": "Fig. 7 Progressions of ACL healing. 1 (a) MRI images of ACL for patient before receiving treatment. (b) ACL at 5 months post-treatment (medium\u2013 low signal intensity). (c) ACL at 9 months post-treatment (low signal intensity). 2 (a) MRI image of ACL pre-treatment. (b) ACL at 3 months post-treatment (medium signal intensity). (c) ACL at 6 months after stem cell procedure (medium\u2013low signal intensity). 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{"pdf_hash": "a823bfcfc1685a33000333c88d3e2e3f24a0bdb8", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig. 1 Common acquired melanocyt nevus, junctional nevus located on the back. a On dermoscopy, a wide irregular (atypical) pigment network (reticular pattern) can be observed. b Routine histopathology shows disarrangement of the rete ridges. Elongated and parallel oriented epidermal cristae are observed at the periphery of the lesion. Pigmented keratinocytes and transepidermal melanin loss is noticed. c The cross-sectional (cross-sectional) HD-OCT imaging demonstrates the pigmented rete ridges and bridging nests of melanocytic nests within the epidermis and papillary dermis as displayed in routine histopathology. d-e On the basic RCM images (Z = 30 lm left and Z = 72 lm right), a meshwork pattern is displayed with nonedged papillae. The dark dermal papillae are irregular in size and shape. No atypical cells are observed in these irregular junctional thickenings. Some compact, monomorphic dense nests are present. f-g On the corresponding en face HD-OCT images (Z = 25 lm and Z = 75 lm), the same features are seen despite the lower resolution. Z value = distance in lm from surface to focus location. Red square in HD-OCT image = corresponding field of view of RCM. 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{"pdf_hash": "6857288b700ceae6f6715fc2c15201b26fddac42", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. FDG PET of medial temporal lobe epilepsy. (A) A typical matching case with hippocampal atrophy and hypometabolism in the left temporal lobe. (B) A case with ambiguous ictal EEG but with definite hypometabolism in the right temporal lobe. (C) An example of bilateral hippocampal atrophy on MRI but unilateral hypometabolism in the right temporal lobe. (D) A non-lesional cryptogenic case on MRI but with mild hypometabolism in the right temporal lobe. 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{"pdf_hash": "bbd23dee0b2bf58b6013217e25074c740247e5d9", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 An example of optical imaging of cultured hippocampal neurons on the PDMS substrate and the CLEM procedure. (a\u2013c) Bright field (a), fluorescence (b), and overlaid (c) images of cultured neurons expressing PSD95-EGFP on the PDMS substrate. Arrows indicate neuropils growing over the square bars. (d) Zoomed-in view of the boxed area in (c). Arrows indicate PSD95-EGFP puncta along the dendrite. (e) Sequential EM images taken by the CLEM software. Overlap between images is preset for montaging. (f) Montaged image of the sequential EM images. (g) Warped LM image to correlate the EM image (f) by the circled patterns in the EM (f) and LM (d) images. 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{"pdf_hash": "111e34ca2fabb0f45d0c6ae657cb2c1d40ed854e", "fig_key": "Figure8", "fig_uri": "6-Figure8-1.png", "text": "Figure 8 Recurrent respiratory papillomatosis in a 27-year-old patient. Contrast-enhanced computed tomography, axial (A, B) and coronal (C) images. Numerous nodules and cystic lesion are seen in the bilateral lungs as well as a large lobulated mass partially obstructing the distal trachea (arrows).", "width": 1066, "height": 322, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 29, 30], "b": [12, 13, 14, 15, 16, 17, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "8ad78261-8a58-4788-ba24-337ffedc95e9", "label": "a", "points": [[5.1, 1.7], [5.1, 313.2], [377.2, 313.2], [377.2, 1.7]], "color": "yellow"}, {"id": "d3fae2e6-a6d9-4909-bb6a-065d95a91354", "label": "a", "points": [[390.7, 3.4], [390.7, 320], [735.9, 320], [735.9, 3.4]], "color": "cyan"}, {"id": "8984f585-6d33-48f6-b2e0-c745e53da8ea", "label": "b", "points": [[747.7, 320], [747.7, 5.1], [1061, 5.1], [1061, 320]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "8", "start": 7, "end": 8, "id": 1}, {"text": "Recurrent", "start": 9, "end": 18, "id": 2}, {"text": "respiratory", "start": 19, "end": 30, "id": 3}, {"text": "papillomatosis", "start": 31, "end": 45, "id": 4}, {"text": "in", "start": 46, "end": 48, "id": 5}, {"text": "a", "start": 49, "end": 50, "id": 6}, {"text": "27-year", "start": 51, "end": 58, "id": 7}, {"text": "-", "start": 58, "end": 59, "id": 8}, {"text": "old", "start": 59, "end": 62, "id": 9}, {"text": "patient", "start": 63, "end": 70, "id": 10}, {"text": ".", "start": 70, "end": 71, "id": 11}, {"text": "Contrast", "start": 72, "end": 80, "id": 12}, {"text": "-", "start": 80, "end": 81, "id": 13}, {"text": "enhanced", "start": 81, "end": 89, "id": 14}, {"text": "computed", "start": 90, "end": 98, "id": 15}, {"text": "tomography", "start": 99, "end": 109, "id": 16}, {"text": ",", "start": 109, "end": 110, "id": 17}, {"text": "axial", "start": 111, "end": 116, "id": 18}, {"text": "(", "start": 117, "end": 118, "id": 19}, {"text": "A", "start": 118, "end": 119, "id": 20}, {"text": ",", "start": 119, "end": 120, "id": 21}, {"text": "B", "start": 121, "end": 122, "id": 22}, {"text": ")", "start": 122, "end": 123, "id": 23}, {"text": "and", "start": 124, "end": 127, "id": 24}, {"text": "coronal", "start": 128, "end": 135, "id": 25}, {"text": "(", "start": 136, "end": 137, "id": 26}, {"text": "C", "start": 137, "end": 138, "id": 27}, {"text": ")", "start": 138, "end": 139, "id": 28}, {"text": "images", "start": 140, "end": 146, "id": 29}, {"text": ".", "start": 146, "end": 147, "id": 30}, {"text": "Numerous", "start": 148, "end": 156, "id": 31}, {"text": "nodules", "start": 157, "end": 164, "id": 32}, {"text": "and", "start": 165, "end": 168, "id": 33}, {"text": "cystic", "start": 169, "end": 175, "id": 34}, {"text": "lesion", "start": 176, "end": 182, "id": 35}, {"text": "are", "start": 183, "end": 186, "id": 36}, {"text": "seen", "start": 187, "end": 191, "id": 37}, {"text": "in", "start": 192, "end": 194, "id": 38}, {"text": "the", "start": 195, "end": 198, "id": 39}, {"text": "bilateral", "start": 199, "end": 208, "id": 40}, {"text": "lungs", "start": 209, "end": 214, "id": 41}, {"text": "as", "start": 215, "end": 217, "id": 42}, {"text": "well", "start": 218, "end": 222, "id": 43}, {"text": "as", "start": 223, "end": 225, "id": 44}, {"text": "a", "start": 226, "end": 227, "id": 45}, {"text": "large", "start": 228, "end": 233, "id": 46}, {"text": "lobulated", "start": 234, "end": 243, "id": 47}, {"text": "mass", "start": 244, "end": 248, "id": 48}, {"text": "partially", "start": 249, "end": 258, "id": 49}, {"text": "obstructing", "start": 259, "end": 270, "id": 50}, {"text": "the", "start": 271, "end": 274, "id": 51}, {"text": "distal", "start": 275, "end": 281, "id": 52}, {"text": "trachea", "start": 282, "end": 289, "id": 53}, {"text": "(", "start": 290, "end": 291, "id": 54}, {"text": "arrows", "start": 291, "end": 297, "id": 55}, {"text": ")", "start": 297, "end": 298, "id": 56}, {"text": ".", "start": 298, "end": 299, "id": 57}]}
{"pdf_hash": "1285e688d223ea593a8599da4a97c3f5389b0454", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. A, transparent rat lens. B, nuclear opacity (44 d). C, total opacification (60 d).", "width": 708, "height": 1416, "subcaptions": {"a": [4, 5, 6, 7, 8, 9], "b": [10, 11, 12, 13, 14, 15, 16, 17, 18], "c": [19, 20, 21, 22, 23, 24, 25, 26, 27]}, "subfigures": [{"id": "958a5cd7-f4b8-472d-ab3c-442f39f28c43", "label": "a", "points": [[11.7, 3], [11.7, 467.2], [706.3, 467.2], [706.3, 3]], "color": "yellow"}, {"id": "36007e7b-e041-4e32-b59f-f11f23dd6f68", "label": "b", "points": [[12.9, 478], [12.9, 929.8], [703, 929.8], [703, 478]], "color": "cyan"}, {"id": "09b02666-2e66-4544-a685-04800c79c4df", "label": "c", "points": [[11.7, 941.4], [11.7, 1397.7], [705.2, 1397.7], [705.2, 941.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": ",", "start": 9, "end": 10, "id": 5}, {"text": "transparent", "start": 11, "end": 22, "id": 6}, {"text": "rat", "start": 23, "end": 26, "id": 7}, {"text": "lens", "start": 27, "end": 31, "id": 8}, {"text": ".", "start": 31, "end": 32, "id": 9}, {"text": "B", "start": 33, "end": 34, "id": 10}, {"text": ",", "start": 34, "end": 35, "id": 11}, {"text": "nuclear", "start": 36, "end": 43, "id": 12}, {"text": "opacity", "start": 44, "end": 51, "id": 13}, {"text": "(", "start": 52, "end": 53, "id": 14}, {"text": "44", "start": 53, "end": 55, "id": 15}, {"text": "d", "start": 56, "end": 57, "id": 16}, {"text": ")", "start": 57, "end": 58, "id": 17}, {"text": ".", "start": 58, "end": 59, "id": 18}, {"text": "C", "start": 60, "end": 61, "id": 19}, {"text": ",", "start": 61, "end": 62, "id": 20}, {"text": "total", "start": 63, "end": 68, "id": 21}, {"text": "opacification", "start": 69, "end": 82, "id": 22}, {"text": "(", "start": 83, "end": 84, "id": 23}, {"text": "60", "start": 84, "end": 86, "id": 24}, {"text": "d", "start": 87, "end": 88, "id": 25}, {"text": ")", "start": 88, "end": 89, "id": 26}, {"text": ".", "start": 89, "end": 90, "id": 27}]}
{"pdf_hash": "29697ecaffd1d01e28f2f93b7b78d73456a767c1", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Fluorescence microscopy of transformed N. benthamiana epidermal cells transiently expressing GFP fusion of CFDV Rep. (A)\u2013(D), association of fluorescence with the nucleus and elements of the cell endomembrane system including the nuclear envelope in cells expressing the GFP\u2013Rep protein. (A, C), cell images reconstructed by superimposition of a series of confocal optical sections. (B), the central confocal optical section of the same cell as in (A). (D), the central confocal optical section of the same cell as in (C). (E), image of a cell expressing free GFP. 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{"pdf_hash": "688cf6f9b9f03e7dc00cfbf917518621ebc1b240", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Coronal fusion PET/CT (A) and PET (B) with 18F-NaF show osteogenic reaction at right femoral head and neck, suspicious for bone involvement secondary to the underlying disease. Pelvic MRI coronal section T1-weighted image with fat suppression after intravenous gadolinium injection (C) shows expansile lesion infiltrating the bone marrow of the right femoral head and neck, suggestive of secondary finding. 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{"pdf_hash": "acf4d20d8457bb95ac1e81e885c3710442b3a4be", "fig_key": "Figure19", "fig_uri": "14-Figure19-1.png", "text": "Fig. 19 Perineural spread of tumor. Patient with squamous carcinoma of the retromolar trigone. CT sagittal images at 0 (a), 6 (b), and 12 (c) months follow-up. Note the progressive infiltration (arrows) of the pterygopalatine fossa (asterisks) with obliteration of the normal fatty tissue. In (c), it is evident the invasion of Meckel\u2019s cave (empty arrow)", "width": 1014, "height": 498, "subcaptions": {"a": [36, 37, 38, 39, 40, 17, 18, 19, 20, 21, 22, 23, 24], "b": [36, 37, 38, 39, 40, 17, 18, 19, 20, 25, 26, 27, 28, 29], "c": [17, 18, 19, 20, 32, 33, 34, 35, 36, 37, 38, 39, 40, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80]}, "subfigures": [{"id": "62d6bc12-e9d8-44a0-b6b6-624196e1d634", "label": "a", "points": [[45.3, 20.6], [45.3, 477.1], [362.5, 477.1], [362.5, 20.6]], "color": "yellow"}, {"id": "d3ea952e-7d32-442f-83a9-a2df69f7d3fd", "label": "b", "points": [[376.9, 15.8], [376.9, 473.9], [666.8, 473.9], [666.8, 15.8]], "color": "cyan"}, {"id": "677177cf-6b02-4890-a109-b6bc00211858", "label": "c", "points": [[676.4, 22.2], [676.4, 467.5], [969.6, 467.5], [969.6, 22.2]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "19", "start": 5, "end": 7, "id": 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{"pdf_hash": "c4ef68734d1b59bb2885c10c742f8a44fa4bb0ac", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. A: Axial T1-weighted MR image of the right distal forearm demonstrates a mass with low signal intensity surrounding the flexor tendons. B: Axial T2-weighted MR image showed a mass with high signal intensity mass and many rice bodies with low signal intensity. C: Sagittal T2-weighted MR image of the right distal forearm showed enlarged tendon sheaths and many small bodies with low signal intensity. D: Axial T1-weighted MR images of the right distal forearm after the administration of gadolinium. The mass which surrounded the flexor tendons was moderately enhanced.", "width": 1024, "height": 1234, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "c": [49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72], "d": [73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100]}, "subfigures": [{"id": "e8d6fef5-b670-4e84-b79b-2b7969f5b92b", "label": "a", "points": [[7.3, 25.6], [7.3, 538.4], [502.3, 538.4], [502.3, 25.6]], "color": "yellow"}, {"id": "8b66f8d4-5fdc-43fd-b199-83a45d62ac5a", "label": "b", "points": [[533.1, 28.9], [533.1, 535.2], [1018.3, 535.2], [1018.3, 28.9]], "color": "cyan"}, {"id": "1dd5f92c-c5c6-4e51-bad2-b2e337e1a1b7", "label": "c", "points": [[5.7, 599.9], [5.7, 1227.5], [330.9, 1227.5], [330.9, 599.9]], "color": 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{"pdf_hash": "365e574e830da32241852876e7d976d60a221f2c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. MRI of patient 1 showing posterior column hyperintensity (white arrow and arrowhead) of cervical spinal cord in T2 axial (a) and T2 midsaggital (b) sections. 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{"pdf_hash": "d1e3455c7b9df76ea253f1c317e4e62f2331c317", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Evaluation of the maxillary teeth on the axial cut of the osteomeatal unit computed tomography: root filling material used in endodontic treatment showed hyperdense spots along the tooth root in the right first molar, second molar and left first molar (arrows, A); the right first premolar was extracted (arrows, B).", "width": 1378, "height": 518, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "b": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "ea4f14db-608c-4a38-b6f1-e6472222d736", "label": "a", "points": [[2.2, 32.7], [2.2, 489.8], [685.8, 489.8], [685.8, 32.7]], "color": "yellow"}, {"id": "6e38b3b0-5770-4293-be1e-1c1d8d4a0c5b", "label": "b", "points": [[692.3, 489.8], [692.3, 39.2], [1371.5, 39.2], [1371.5, 489.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Evaluation", "start": 8, "end": 18, "id": 4}, {"text": "of", "start": 19, "end": 21, "id": 5}, {"text": "the", "start": 22, "end": 25, "id": 6}, {"text": "maxillary", "start": 26, "end": 35, "id": 7}, {"text": "teeth", "start": 36, "end": 41, "id": 8}, {"text": "on", "start": 42, "end": 44, "id": 9}, {"text": "the", "start": 45, "end": 48, "id": 10}, {"text": "axial", "start": 49, "end": 54, "id": 11}, {"text": "cut", "start": 55, "end": 58, "id": 12}, {"text": "of", "start": 59, "end": 61, "id": 13}, {"text": "the", "start": 62, "end": 65, "id": 14}, {"text": "osteomeatal", "start": 66, "end": 77, "id": 15}, {"text": "unit", "start": 78, "end": 82, "id": 16}, {"text": "computed", "start": 83, "end": 91, "id": 17}, {"text": "tomography", "start": 92, "end": 102, "id": 18}, {"text": ":", "start": 102, "end": 103, "id": 19}, {"text": "root", "start": 104, "end": 108, "id": 20}, {"text": "filling", "start": 109, "end": 116, "id": 21}, {"text": "material", "start": 117, "end": 125, "id": 22}, {"text": "used", "start": 126, "end": 130, "id": 23}, {"text": "in", "start": 131, "end": 133, "id": 24}, {"text": "endodontic", "start": 134, "end": 144, "id": 25}, {"text": "treatment", "start": 145, "end": 154, "id": 26}, {"text": "showed", "start": 155, "end": 161, "id": 27}, {"text": "hyperdense", "start": 162, "end": 172, "id": 28}, {"text": "spots", "start": 173, "end": 178, "id": 29}, {"text": "along", "start": 179, "end": 184, "id": 30}, {"text": "the", "start": 185, "end": 188, "id": 31}, {"text": "tooth", "start": 189, "end": 194, "id": 32}, {"text": "root", "start": 195, "end": 199, "id": 33}, {"text": "in", "start": 200, "end": 202, "id": 34}, {"text": "the", "start": 203, "end": 206, "id": 35}, {"text": "right", "start": 207, "end": 212, "id": 36}, {"text": "first", "start": 213, "end": 218, "id": 37}, {"text": "molar", "start": 219, "end": 224, "id": 38}, {"text": ",", "start": 224, "end": 225, "id": 39}, {"text": "second", "start": 226, "end": 232, "id": 40}, {"text": "molar", "start": 233, "end": 238, "id": 41}, {"text": "and", "start": 239, "end": 242, "id": 42}, {"text": "left", "start": 243, "end": 247, "id": 43}, {"text": "first", "start": 248, "end": 253, "id": 44}, {"text": "molar", "start": 254, "end": 259, "id": 45}, {"text": "(", "start": 260, "end": 261, "id": 46}, {"text": "arrows", "start": 261, "end": 267, "id": 47}, {"text": ",", "start": 267, "end": 268, "id": 48}, {"text": "A", "start": 269, "end": 270, "id": 49}, {"text": ")", "start": 270, "end": 271, "id": 50}, {"text": ";", "start": 271, "end": 272, "id": 51}, {"text": "the", "start": 273, "end": 276, "id": 52}, {"text": "right", "start": 277, "end": 282, "id": 53}, {"text": "first", "start": 283, "end": 288, "id": 54}, {"text": "premolar", "start": 289, "end": 297, "id": 55}, {"text": "was", "start": 298, "end": 301, "id": 56}, {"text": "extracted", "start": 302, "end": 311, "id": 57}, {"text": "(", "start": 312, "end": 313, "id": 58}, {"text": "arrows", "start": 313, "end": 319, "id": 59}, {"text": ",", "start": 319, "end": 320, "id": 60}, {"text": "B", "start": 321, "end": 322, "id": 61}, {"text": ")", "start": 322, "end": 323, "id": 62}, {"text": ".", "start": 323, "end": 324, "id": 63}]}
{"pdf_hash": "fecb31ad9eecc57a338c2b6d882b4c77ee3f1e55", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Figure 6. Right abdominal compression image illustrating incidental ileocecal intussusception occurring coincidentally at the time of imaging in a 4-month-old patient with rotavirus infection. Transverse (left) and longitudinal (right) images at the level of the hepatic flexure outline the diagnostic bowel-within-bowel appearance. 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{"pdf_hash": "eaeb72b2f7deb4d1b8d77c45c573c7a051569966", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 A 46-year-old woman admitted for evaluation of venous bypasses. After occlusion of multiple visceral arteries 2 years previously, one bypass was connected from the inferior aorta to the celiac axis and superior mesenteric artery, and another from the right common iliac artery to branches of the superior mesenteric and common hepatic artery. Axial image (a) and axial MIP (b) show occlusion of the bypass (arrows). Lateral MIP (c) demonstrates the occluded bypass (arrow) and the unaltered occlusion of the celiac and superior mesenteric artery (arrowhead). VR image (d) depicts the occluded first bypass (arrow) and open second bypass (arrowhead). 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{"pdf_hash": "035205848a64ee5d4b81090463cc4e8b9f044f18", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. A lumbar spine MRI shows an irregular shaped right presacral mass (arrow) with (A) heterogeneous STIR hyperintensity and (B) T1 hypointensity. (C) CT of the pelvis shows a complex mass (arrow) with central necrosis and a thick enhancing wall extending into the right S2 neural foramen with lytic bone destruction. (D) Pelvic CT shows a 6x5x6 cm mass (arrow) compressing the right piriformis muscle posteriorly. 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{"pdf_hash": "6df41167b111c1a1aa12a380f800fc5ef87327bd", "fig_key": "Figure16", "fig_uri": "11-Figure16-1.png", "text": "FIGURE 16. Sacral chordoma. Forty-two-year-old male with lower back pain and pelvic fullness. A, Sagittal noncontrast CT image of the sacrum shows a large mass arising from the distal sacrum (yellow arrow), with internal coarse calcification (white arrow). B, Sagittal T1-W MR image shows the mass is isointense to muscle, with robust enhancement on postcontrast fat-saturated sagittal T1-W image C. The mass has hyperintense T2-W signal on sagittal fat-saturated T2-W imaging. Note the internal area of dark signal (D, black arrow), corresponding to the calcifications on the CT (A, white arrow). 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{"pdf_hash": "3499ace40ca69459ce8ea326baf13c4f9bffd015", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. A, Normal brainstem and cerebellum in a patient with a clinical diagnosis of Parkinson disease (sagittal section, 1.5 T, T1 weighting). B, Mild brainstem and cerebellar atrophy in a patient with a clinical diagnosis of multiple-system atrophy with predominant parkinsonism (sagittal section, 1.5 T, T1 weighting). 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{"pdf_hash": "da28152e17896d20743f9274a3a0a67a5a8208d0", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. (A) Magnetic resonance imaging-sagittal view of a 64-yearold male with flexion distraction injury at the C4-5 level. (B) Postoperative X-ray at 1 year showing reduction and fusion with trabecular continuity at the C4-5 level. A B", "width": 638, "height": 496, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "78b49a6a-2239-4130-9dd7-e2d63a987ee1", "label": "a", "points": [[4.3, 1.9], [4.3, 461.5], [312.7, 461.5], [312.7, 1.9]], "color": "yellow"}, {"id": "00534571-7866-4efb-904c-b3e64def4f36", "label": "b", "points": [[330.9, 4.9], [330.9, 463.5], [637.2, 463.5], [637.2, 4.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Magnetic", "start": 12, "end": 20, "id": 7}, {"text": "resonance", "start": 21, "end": 30, "id": 8}, {"text": "imaging", "start": 31, "end": 38, "id": 9}, {"text": "-", "start": 38, "end": 39, "id": 10}, {"text": "sagittal", "start": 39, "end": 47, "id": 11}, {"text": "view", "start": 48, "end": 52, "id": 12}, {"text": "of", "start": 53, "end": 55, "id": 13}, {"text": "a", "start": 56, "end": 57, "id": 14}, {"text": "64-yearold", "start": 58, "end": 68, "id": 15}, {"text": "male", "start": 69, "end": 73, "id": 16}, {"text": "with", "start": 74, "end": 78, "id": 17}, {"text": "flexion", "start": 79, "end": 86, "id": 18}, {"text": "distraction", "start": 87, "end": 98, "id": 19}, {"text": "injury", "start": 99, "end": 105, "id": 20}, {"text": "at", "start": 106, "end": 108, "id": 21}, {"text": "the", "start": 109, "end": 112, "id": 22}, {"text": "C4", "start": 113, "end": 115, "id": 23}, {"text": "-", "start": 115, "end": 116, "id": 24}, {"text": "5", "start": 116, "end": 117, "id": 25}, {"text": "level", "start": 118, "end": 123, "id": 26}, {"text": ".", "start": 123, "end": 124, "id": 27}, {"text": "(", "start": 125, "end": 126, "id": 28}, {"text": "B", "start": 126, "end": 127, "id": 29}, {"text": ")", "start": 127, "end": 128, "id": 30}, {"text": "Postoperative", "start": 129, "end": 142, "id": 31}, {"text": "X", "start": 143, "end": 144, "id": 32}, {"text": "-", "start": 144, "end": 145, "id": 33}, {"text": "ray", "start": 145, "end": 148, "id": 34}, {"text": "at", "start": 149, "end": 151, "id": 35}, {"text": "1", "start": 152, "end": 153, "id": 36}, {"text": "year", "start": 154, "end": 158, "id": 37}, {"text": "showing", "start": 159, "end": 166, "id": 38}, {"text": "reduction", "start": 167, "end": 176, "id": 39}, {"text": "and", "start": 177, "end": 180, "id": 40}, {"text": "fusion", "start": 181, "end": 187, "id": 41}, {"text": "with", "start": 188, "end": 192, "id": 42}, {"text": "trabecular", "start": 193, "end": 203, "id": 43}, {"text": "continuity", "start": 204, "end": 214, "id": 44}, {"text": "at", "start": 215, "end": 217, "id": 45}, {"text": "the", "start": 218, "end": 221, "id": 46}, {"text": "C4", "start": 222, "end": 224, "id": 47}, {"text": "-", "start": 224, "end": 225, "id": 48}, {"text": "5", "start": 225, "end": 226, "id": 49}, {"text": "level", "start": 227, "end": 232, "id": 50}, {"text": ".", "start": 232, "end": 233, "id": 51}, {"text": "A", "start": 234, "end": 235, "id": 52}, {"text": "B", "start": 236, "end": 237, "id": 53}]}
{"pdf_hash": "bb511a2088a6f08bc69bd3f756e6fbea679a0751", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "FIGURE 2 | Regions with smaller white matter volumes in 23 moderate nicotine dependence smokers and 30 severe nicotine dependence smokers than in non-smokers. This image shows the overlap (orange) regions of the smaller white matter in 23 moderate nicotine dependence smokers (red) and 30 severe nicotine dependence smokers (yellow) than in 53 non-smokers. Overall thresholds of significance were set at P < 0.05 (AlphaSim corrected). 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{"pdf_hash": "5fc0b617bcff4a9f6ee5ee9572e9b167b1de35ba", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 A 27-year-old professional hockey player was evaluated for right hip pain. a A pre-operative cross-table lateral radiograph demonstrated convexity at the anterior femoral head\u2013neck junction. b The presence of a cam lesion was verified arthroscopically. 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{"pdf_hash": "a023b8d02728d9517f7dd0c1cd19522e0081449b", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Coronal (A) and axial (B) Ce Se T1W MRI showing a large and heterogeneous sellar mass with lateral and anterior extension involving left orbital apex, orbital fissures, and optic canal. The arrow indicates the encasing of the optical nerve.", "width": 666, "height": 422, "subcaptions": {"a": [3, 4, 5, 6, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "13f2b10d-5a37-4b81-898c-458503bbe3d4", "label": "a", "points": [[2.4, 35.6], [2.4, 417.5], [308.6, 417.5], [308.6, 35.6]], "color": "yellow"}, {"id": "cec64796-4fb5-4226-9e24-a5f50475c4b2", "label": "b", "points": [[330.7, 30.4], [330.7, 417.5], [661, 417.5], [661, 30.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Coronal", "start": 10, "end": 17, "id": 3}, {"text": "(", "start": 18, "end": 19, "id": 4}, {"text": "A", "start": 19, "end": 20, "id": 5}, {"text": ")", "start": 20, "end": 21, "id": 6}, {"text": "and", "start": 22, "end": 25, "id": 7}, {"text": "axial", "start": 26, "end": 31, "id": 8}, {"text": "(", "start": 32, "end": 33, "id": 9}, {"text": "B", "start": 33, "end": 34, "id": 10}, {"text": ")", "start": 34, "end": 35, "id": 11}, {"text": "Ce", "start": 36, "end": 38, "id": 12}, {"text": "Se", "start": 39, "end": 41, "id": 13}, {"text": "T1W", "start": 42, "end": 45, "id": 14}, {"text": "MRI", "start": 46, "end": 49, "id": 15}, {"text": "showing", "start": 50, "end": 57, "id": 16}, {"text": "a", "start": 58, "end": 59, "id": 17}, {"text": "large", "start": 60, "end": 65, "id": 18}, {"text": "and", "start": 66, "end": 69, "id": 19}, {"text": "heterogeneous", "start": 70, "end": 83, "id": 20}, {"text": "sellar", "start": 84, "end": 90, "id": 21}, {"text": "mass", "start": 91, "end": 95, "id": 22}, {"text": "with", "start": 96, "end": 100, "id": 23}, {"text": "lateral", "start": 101, "end": 108, "id": 24}, {"text": "and", "start": 109, "end": 112, "id": 25}, {"text": "anterior", "start": 113, "end": 121, "id": 26}, {"text": "extension", "start": 122, "end": 131, "id": 27}, {"text": "involving", "start": 132, "end": 141, "id": 28}, {"text": "left", "start": 142, "end": 146, "id": 29}, {"text": "orbital", "start": 147, "end": 154, "id": 30}, {"text": "apex", "start": 155, "end": 159, "id": 31}, {"text": ",", "start": 159, "end": 160, "id": 32}, {"text": "orbital", "start": 161, "end": 168, "id": 33}, {"text": "fissures", "start": 169, "end": 177, "id": 34}, {"text": ",", "start": 177, "end": 178, "id": 35}, {"text": "and", "start": 179, "end": 182, "id": 36}, {"text": "optic", "start": 183, "end": 188, "id": 37}, {"text": "canal", "start": 189, "end": 194, "id": 38}, {"text": ".", "start": 194, "end": 195, "id": 39}, {"text": "The", "start": 196, "end": 199, "id": 40}, {"text": "arrow", "start": 200, "end": 205, "id": 41}, {"text": "indicates", "start": 206, "end": 215, "id": 42}, {"text": "the", "start": 216, "end": 219, "id": 43}, {"text": "encasing", "start": 220, "end": 228, "id": 44}, {"text": "of", "start": 229, "end": 231, "id": 45}, {"text": "the", "start": 232, "end": 235, "id": 46}, {"text": "optical", "start": 236, "end": 243, "id": 47}, {"text": "nerve", "start": 244, "end": 249, "id": 48}, {"text": ".", "start": 249, "end": 250, "id": 49}]}
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{"pdf_hash": "127604aaef721f247524084fb27eb82fb09fc8dd", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 (A) Axial T2 weighted magnetic resonance imaging sequence; solitary lesion (white arrow) in the right occipital lobe in a 3 year old boy. (B) Axial T2 weighted gradient echo sequence; multiple supratentorial cerebral cavernous malformations (black arrows) in a young adult.", "width": 634, "height": 412, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "ce9e9a32-d270-455d-bbfd-76b32f89c205", "label": "a", "points": [[7.2, 4.3], [7.2, 376.9], [281.6, 376.9], [281.6, 4.3]], "color": "yellow"}, {"id": "5c6ddf43-4c91-42a8-81ad-c23cba85be37", "label": "b", "points": [[292.6, 5.3], [292.6, 376.9], [629.2, 376.9], [629.2, 5.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Axial", "start": 13, "end": 18, "id": 5}, {"text": "T2", "start": 19, "end": 21, "id": 6}, {"text": "weighted", "start": 22, "end": 30, "id": 7}, {"text": "magnetic", "start": 31, "end": 39, "id": 8}, {"text": "resonance", "start": 40, "end": 49, "id": 9}, {"text": "imaging", "start": 50, "end": 57, "id": 10}, {"text": "sequence", "start": 58, "end": 66, "id": 11}, {"text": ";", "start": 66, "end": 67, "id": 12}, {"text": "solitary", "start": 68, "end": 76, "id": 13}, {"text": "lesion", "start": 77, "end": 83, "id": 14}, {"text": "(", "start": 84, "end": 85, "id": 15}, {"text": "white", "start": 85, "end": 90, "id": 16}, {"text": "arrow", "start": 91, "end": 96, "id": 17}, {"text": ")", "start": 96, "end": 97, "id": 18}, {"text": "in", "start": 98, "end": 100, "id": 19}, {"text": "the", "start": 101, "end": 104, "id": 20}, {"text": "right", "start": 105, "end": 110, "id": 21}, {"text": "occipital", "start": 111, "end": 120, "id": 22}, {"text": "lobe", "start": 121, "end": 125, "id": 23}, {"text": "in", "start": 126, "end": 128, "id": 24}, {"text": "a", "start": 129, "end": 130, "id": 25}, {"text": "3", "start": 131, "end": 132, "id": 26}, {"text": "year", "start": 133, "end": 137, "id": 27}, {"text": "old", "start": 138, "end": 141, "id": 28}, {"text": "boy", "start": 142, "end": 145, "id": 29}, {"text": ".", "start": 145, "end": 146, "id": 30}, {"text": "(", "start": 147, "end": 148, "id": 31}, {"text": "B", "start": 148, "end": 149, "id": 32}, {"text": ")", "start": 149, "end": 150, "id": 33}, {"text": "Axial", "start": 151, "end": 156, "id": 34}, {"text": "T2", "start": 157, "end": 159, "id": 35}, {"text": "weighted", "start": 160, "end": 168, "id": 36}, {"text": "gradient", "start": 169, "end": 177, "id": 37}, {"text": "echo", "start": 178, "end": 182, "id": 38}, {"text": "sequence", "start": 183, "end": 191, "id": 39}, {"text": ";", "start": 191, "end": 192, "id": 40}, {"text": "multiple", "start": 193, "end": 201, "id": 41}, {"text": "supratentorial", "start": 202, "end": 216, "id": 42}, {"text": "cerebral", "start": 217, "end": 225, "id": 43}, {"text": "cavernous", "start": 226, "end": 235, "id": 44}, {"text": "malformations", "start": 236, "end": 249, "id": 45}, {"text": "(", "start": 250, "end": 251, "id": 46}, {"text": "black", "start": 251, "end": 256, "id": 47}, {"text": "arrows", "start": 257, "end": 263, "id": 48}, {"text": ")", "start": 263, "end": 264, "id": 49}, {"text": "in", "start": 265, "end": 267, "id": 50}, {"text": "a", "start": 268, "end": 269, "id": 51}, {"text": "young", "start": 270, "end": 275, "id": 52}, {"text": "adult", "start": 276, "end": 281, "id": 53}, {"text": ".", "start": 281, "end": 282, "id": 54}]}
{"pdf_hash": "7a4c30b09259ac461fd12678e438211fe02f20a2", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Sagittal cartilage-sensitive, fast-spin echo magnetic resonance images of a TruFit bone graft substitute plug (BGS) at 6 months, 12 months, and 38 months postoperatively. The appearance of the plug parallels its biological incorporation, demonstrating unfavorable characteristics during the phase of resorption and early incorporation at intermediate postoperative follow-up. Resorption at the plug-native bone interface was seen in greater than 60% of TruFit BGS plugs at approximately 12 months.", "width": 660, "height": 1426, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 35, 36], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 29, 30, 35, 36, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88], "c": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 33, 34, 35, 36]}, "subfigures": [{"id": "374e84a9-6f95-44de-bea0-5e561f5722e2", "label": "a", "points": [[33.9, 21.5], [33.9, 462.6], [632.4, 462.6], [632.4, 21.5]], "color": "yellow"}, {"id": "edbd9914-0795-44b3-bfbe-0a4e6f54f7a3", "label": "b", "points": [[30.8, 483.5], [30.8, 926.6], [629.2, 926.6], [629.2, 483.5]], "color": "cyan"}, {"id": "d0e6de85-eb42-4e52-bd33-0b8ba81ea32b", "label": "c", "points": [[31.8, 944], 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{"pdf_hash": "1ca7145625f33ba2b06035389e6582cabcc9ab0d", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Acute ethanol-induced histopathological changes in the livers 6 h after intragastric administration of 6g/kg ethanol: A, control; B, zinc; C, ethanol; and D, zinc \u03e9 ethanol (E and F are higher magnifications of C and D, respectively). The treatment protocol was as the same as that described for Fig. 1. The major histopathological change induced by ethanol in mouse liver was microvesicular steatosis (arrows). In addition, ethanol administration caused hepatocyte enlargement with nuclear dissolution (indicative of necrosis; arrowheads). Zinc pretreatment suppressed these ethanol-induced alterations. CV, central vein. H&E staining, magnifications: A through D, 260\u03eb and E and F, 520\u03eb.", "width": 698, "height": 864, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 56], "b": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 28, 29, 30, 56], "c": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 32, 33, 34, 56], "d": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 37, 38, 39, 40, 41, 56], "e": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 32, 33, 34, 42, 43, 46, 47, 48, 49, 50, 55, 56], "f": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 37, 38, 39, 40, 41, 42, 45, 46, 47, 48, 49, 52, 55, 56]}, "subfigures": [{"id": "d54be645-1212-49b3-9f8c-0065ca6974fe", "label": "a", "points": [[7.9, 2.6], [7.9, 270.5], [340.9, 270.5], [340.9, 2.6]], "color": "yellow"}, {"id": "cc5ec3f6-83a7-48ee-80ca-4f3004745b59", 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{"pdf_hash": "ddd0409cf6643d42d61a07238a73c9f9fbdad752", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 \u2013 A: Axial T1-weighted image. The mass is almost isointense to the thoracic muscles (white asterisk). B: Coronal gradient-echo T2 image. The mass extends upward to the subcarinal region. The lesion exhibits a heterogeneous hypointensity (white asterisk), consistent with the presence of fibrous component. C: Axial T1-weighted image, post-gadolinium image. The mass (black asterisk) shows contrast uptake, more homogeneous in its anterior part. Note that the uptake is less homogeneous in its posterior part. 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{"pdf_hash": "27867a3cea6439c6a661ed1e1d9670f8ee02888c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 Probe placements in the amygdala. a A representative photomicrograph of a cresylstained coronal section showing the localization of the tip of the membrane of a microdialysis probe (arrowhead) within the BA/LA. b Schematic drawings of the localization of the microdialysis membranes (bold black lines) used in the present study within and outside of the BA/LA. BA basal amygdala, LA lateral amygdala. 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{"pdf_hash": "403bbf3d58a17982a3b2ee1e20c855f4b247dacc", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 Overview of workflow used to perform patient specific simulation for IRE treatment performed on a 70-year-old man with Gleason 9 recurrence after radiation therapy (patient 6). a T1 weighted post contrast MRI showed a tumor (center marked with an asterisk, boundary with solid line) in the right peripheral zone. b Intra-operative axial US guided needle placement to the tumor (5 IRE needles, white arrows). The intra-operative US image annotated to demarcate the ablation probes (dashed arrows), the outline of the prostate, the rectum, and the neurovascular bundles (NVB) (solid lines). Clinical treatment planning data were compiled and the MR images from the corresponding axial plane were used to identify critical structures for segmentation. c Follow-up axial enhanced T1w with fat saturation MR imaging performed 15 days after ablation was used to demarcate the ablation defect (solid line) and showed size and shape of the ablative zone (area: 701 mm2). d Simulation predicted ablation zone (white with blue boundary) at the electric field strength contour (700 V/cm; area 624 mm2, arrowhead). Image plotted using gradient shading with regions of highest field strength (700 V/cm and stronger) appearing light and lower field strengths appearing dark. 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{"pdf_hash": "94d44bad77ceebdc14dafee410e72ae4df639504", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. (a) A parasagittal overview of the proliferation zones in the brain of an adult zebrafish. The zebrafish was pulsed for 4 h with BrdU and whole mount stained. (b) A parasagittal overview of the zebrafish telencephalon stained with PSA-NCAM showing a chain of cells along the telencephalic ventricle immunopositive for the PSA-NCAM. (c) Cross-section and overview of the proliferative zones (red dots) in the everted fish telencephalon (arrow). Boxed region shows the field of view in (d ) and (e). (d ) A cross-section through the dorsal telencephalon of an adult zebrafish showing BrdU-labelled cells (green) along the lateral margin, as well as Hu-positive neurons (red) and S100b-positive glia (blue). The fish was pulsed for 2 days with BrdU. (e) A crosssection from a similar level to (e) showing PSA-NCAM-positive cells (red) along the lateral margin as well as S100b-positive glia (green). ( f, g) Cross-section of the pretectum of an adult zebrafish showing a newly generated tyrosine hydroxylase-positive neuron. (h, i ) Cross-section of the hypothalamus showing newly generated serotonin neurons (Grandel et al. 2006). DT, dorsal telencephalon; VT, ventral telencephalon; TV, tectal ventricle. ( f )\u2013(i ) is reprinted with kind permission from Grandel et al. 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{"pdf_hash": "1ee51d3e7ef7d530e6110361e8ec5fa13e76652b", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "Fig. 6 Overexpression of p60TRP in transgenic mice using a bioluminescence reporter gene. Transgene-vector: Map of the vector used for transgenic expression of p60TRP in mice. Schematic representation of plasmid pTGV.60TRP (TGV: transgenic vector), harbouring the synapsin 1 promoter (Syn1P), p60TRP cDNA, an IRES domain, the luciferase cDNA as a reporter gene to identify p60TRP expression using in vivo live bioluminescence imaging, the woodchuck hepatitis virus post-transcriptional regulatory element (WPRE), and the -globin 3 untranslated region containing its own polyadenylation signal ( -glob, 3 UTR and pA, respectively) (A). Bioluminescence luciferase activity imaging in live mice showing p60TRP expression in the brains of transgenic (tg) mice compared with their wild-type corresponding littermates (left: females, 3 months old, strain 31; right: females, 1 month old, strain 38) (B). Bioluminescence luciferase activity imaging of brain slices. Upper panel: mouse strain 38 (female, 1 month old), coronal brain section; lower panel: mouse strain 38 (male, 1 month old), coronal brain section (C). Brain imaging of mouse strain 38, sagittal brain section (left: female, 1 month old, right: wild-type female littermate) (D). Western blot analysis showing p60TRP overexpression in the cortex (Cx) and hippocampus (Hp) of transgenic mice (strain 38, female, 1 month old) compared to wild-type littermates (C) (E). Analysis of luciferase activity assay was performed as described in supplemental \u2018Materials and methods\u2019. Only p60TRP transgenic mice revealed luciferase activity. 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{"pdf_hash": "0c5c8c143055bba3c898a2bcf8d5b0e66b346562", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (a) Computed tomography (CT) angiography showing the left coronary artery (LC) from the pulmonary trunk (RCA: right coronary artery; AD: anterior descending artery; and Cx: circumflex artery). (b) CT angiotomography showing the coronary collateral network. (c) CT angiotomography showing the left coronary artery aneurysm.", "width": 990, "height": 962, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "b": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54], "c": [55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "2f892af4-9324-400d-94d0-7f6ff91b2302", "label": "a", "points": [[15.6, 3.1], [15.6, 389.4], [483.3, 389.4], [483.3, 3.1]], "color": "yellow"}, {"id": "42b812ca-d230-4693-9026-cfbc9387cfad", "label": "b", "points": [[516.1, 392.6], [516.1, 1.6], [955.6, 1.6], [955.6, 392.6]], "color": "cyan"}, {"id": "e4004440-bd13-46d9-995f-b30bc0a154bd", "label": "c", "points": [[248.7, 455.1], [248.7, 886.8], [724.1, 886.8], [724.1, 455.1]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Computed", "start": 14, "end": 22, "id": 6}, {"text": "tomography", "start": 23, "end": 33, "id": 7}, {"text": "(", "start": 34, "end": 35, "id": 8}, {"text": "CT", "start": 35, "end": 37, "id": 9}, {"text": ")", "start": 37, "end": 38, "id": 10}, {"text": "angiography", "start": 39, "end": 50, "id": 11}, {"text": "showing", "start": 51, "end": 58, "id": 12}, {"text": "the", "start": 59, "end": 62, "id": 13}, {"text": "left", "start": 63, "end": 67, "id": 14}, {"text": "coronary", "start": 68, "end": 76, "id": 15}, {"text": "artery", "start": 77, "end": 83, "id": 16}, {"text": "(", "start": 84, "end": 85, "id": 17}, {"text": "LC", "start": 85, "end": 87, "id": 18}, {"text": ")", "start": 87, "end": 88, "id": 19}, {"text": "from", "start": 89, "end": 93, "id": 20}, {"text": "the", "start": 94, "end": 97, "id": 21}, {"text": "pulmonary", "start": 98, "end": 107, "id": 22}, {"text": "trunk", "start": 108, "end": 113, "id": 23}, {"text": "(", "start": 114, "end": 115, "id": 24}, {"text": "RCA", "start": 115, "end": 118, "id": 25}, {"text": ":", "start": 118, "end": 119, "id": 26}, {"text": "right", "start": 120, "end": 125, "id": 27}, {"text": "coronary", "start": 126, "end": 134, "id": 28}, {"text": "artery", "start": 135, "end": 141, "id": 29}, {"text": ";", "start": 141, "end": 142, "id": 30}, {"text": "AD", "start": 143, "end": 145, "id": 31}, {"text": ":", "start": 145, "end": 146, "id": 32}, {"text": "anterior", "start": 147, "end": 155, "id": 33}, {"text": "descending", "start": 156, "end": 166, "id": 34}, {"text": "artery", "start": 167, "end": 173, "id": 35}, {"text": ";", "start": 173, "end": 174, "id": 36}, {"text": "and", "start": 175, "end": 178, "id": 37}, {"text": "Cx", "start": 179, "end": 181, "id": 38}, {"text": ":", "start": 181, "end": 182, "id": 39}, {"text": "circumflex", "start": 183, "end": 193, "id": 40}, {"text": "artery", "start": 194, "end": 200, "id": 41}, {"text": ")", "start": 200, "end": 201, "id": 42}, {"text": ".", "start": 201, "end": 202, "id": 43}, {"text": "(", "start": 203, "end": 204, "id": 44}, {"text": "b", "start": 204, "end": 205, "id": 45}, {"text": ")", "start": 205, "end": 206, "id": 46}, {"text": "CT", "start": 207, "end": 209, "id": 47}, {"text": "angiotomography", "start": 210, "end": 225, "id": 48}, {"text": "showing", "start": 226, "end": 233, "id": 49}, {"text": "the", "start": 234, "end": 237, "id": 50}, {"text": "coronary", "start": 238, "end": 246, "id": 51}, {"text": "collateral", "start": 247, "end": 257, "id": 52}, {"text": "network", "start": 258, "end": 265, "id": 53}, {"text": ".", "start": 265, "end": 266, "id": 54}, {"text": "(", "start": 267, "end": 268, "id": 55}, {"text": "c", "start": 268, "end": 269, "id": 56}, {"text": ")", "start": 269, "end": 270, "id": 57}, {"text": "CT", "start": 271, "end": 273, "id": 58}, {"text": "angiotomography", "start": 274, "end": 289, "id": 59}, {"text": "showing", "start": 290, "end": 297, "id": 60}, {"text": "the", "start": 298, "end": 301, "id": 61}, {"text": "left", "start": 302, "end": 306, "id": 62}, {"text": "coronary", "start": 307, "end": 315, "id": 63}, {"text": "artery", "start": 316, "end": 322, "id": 64}, {"text": "aneurysm", "start": 323, "end": 331, "id": 65}, {"text": ".", "start": 331, "end": 332, "id": 66}]}
{"pdf_hash": "3f0d19e2f7b2e9683955e2821a79190db62d41d7", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2 (a) CT scan showing enhanced right ureter suggestive of ureteritis (white arrow head and white arrow in magnified image). (b) Ultrasound scan (USS) showing right ureterocoele (dotted white arrow). (c) USS showing right hydronephrosis (dashed white arrow). 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{"pdf_hash": "abc6fe73fd34d39a72fc1deb4640a69727bf8f45", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Three-dimensional digital template software \u201cATHENA\u201d. Two X-ray images of the knee joint undertaken with a 3D marker attached to the surface of the patient\u2019s lower leg (a, b). The silhouette made by the marker on the images is used to couple the two X-ray images three dimensionally (c). Pre-operative CTwas further matched, thus making it possible to assess postoperative conditions in preoperative three-dimensional digital template software \u201cATHENA\u201d (d). 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{"pdf_hash": "39f201d4eafbbc07f8165bc045fa6b0597542b30", "fig_key": "Figure7", "fig_uri": "8-Figure7-1.png", "text": "Figure 7. RNA in situ hybridization of whole-mount mouse embryos. (a) Ventral view and (b) dorsal view of E9.5 embryo. Eya4 is expressed in the nasal placode (np), the otic vesicle (ov) and in two stripes flanking the dorsal midline above the level of the developing forelimb (arrowhead in b). (c) E10.5 embryo. Eya4 is expressed in the lateral nasal process (lnp), mandibular process (mb), forelimb (fl) and hindlimb (hl). The eye (ey) is negative. The signal in the hindbrain (hb) is due to trapping. (d) E11.5 embryos hybridized with antisense (left) and sense (right) probes. Eya4 is expressed in the craniofacial mesenchyme (cfm) above the nose and between the eyes, the future external auditory meatus (eam), the dermamyotome (dm), the forelimb and the hindlimb. Strong expression was also seen in a domain linking the dermamyotome with the limb (arrowhead). (e) Transverse vibratome section of an E11.5 whole-mount embryo at the level of the forelimb. Eya4 is expressed strongly in the dermamyotomal compartment of the somites but not in the neural tube (nt) or dorsal root ganglia (drg). Eya4 is also expressed in streams of cells which appear to be moving from the dermamyotome into the forelimb. (f) Transverse vibratome section through the head of an E11.5 whole-mount embryo. Eya4 expression is clearly visible in the craniofacial mesenchyme overlying the olfactory epithelium (oe). The eye, including the lens (l), is negative. (g) Whole-mount hybridization of hindlimb plate (left) and forelimb plate (right) at E12.5. Eya4 is expressed in the vicinity of the condensing digits. 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{"pdf_hash": "09601f39cd885da37c84b484d8a2e8a0649f4ee7", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Axon outgrowth and cytoskeletal organization, but neither neuronal specification nor early stages of cellular polarization, were severely compromised with hnRNP K knockdown. (A)\uf020Immunostained optical section of a stage 40 Xenopus tadpole demonstrates suppression of hnRNP K expression on the injected side by hnRNP K MO (below dots). SC (inside dashed lines), spinal cord; arrowheads, hnRNP K staining of muscle nuclei on the uninjected side. (B-Db) Suppression of axon outgrowth on the injected side of stage 40 tadpoles [B(bottom),Cb,Db] revealed by immunostaining for the indicated axonal markers. A and B are horizontal and Ca-Db parasagittal sections. Arrowheads in Cb and in Da and Db indicate examples of atrophied axons and neuronal perikarya, respectively. Arrowheads in B indicate normally projecting motor axons on the uninjected side. (Ea-Gc) Organization of the indicated cytoskeletal polymers was severely disrupted in neurons of bilaterally injected hnRNP K MO (PK MO) cultures compared with those of control MO (Ea,Fa,Ga), which appeared normal. With hnRNP K MO, Factin circumscribed perikarya, but was asymmetrically distributed (Eb,Ec); microtubules formed an anastomosing network (Fb,Fc); neuronal intermediate filaments were twisted and radiated outward in multiple directions (Gb,Gc). (Ha-Id) Double immunostaining for N-\uf062 tubulin and Par6 as indicated. With control MO (Ha,Hb), Par 6 staining was punctate and filled neuronal perikarya and axons (arrowheads, growth cone). With hnRNP K MO (Ia-Id), neuronal perikaryal microtubules (Ic,Id) were poorly organized and failed to correspond with an asymmetric hotspot of Par6 immunostaining (Ia,Ib). 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{"pdf_hash": "3fb5610279cb43826c416c01f391d7385517c917", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 a Radiography, b gastrografin enema examination, and c computed tomography (CT) revealed stenosis of the descending colon (arrows) and remarkable distention on the oral side of the descending colon. Barium nodules were detected in the peritoneal cavity, especially near the anastomosis", "width": 1364, "height": 480, "subcaptions": {"a": [32, 33, 34, 3, 4, 35, 36, 37, 38, 18, 19, 20, 21, 22, 23, 27, 28, 29, 30, 31], "b": [6, 7, 8, 9, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "c": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "575bf4e4-3581-4f26-af87-3297a6703f58", "label": "a", "points": [[11.9, 6.1], [11.9, 441.4], [445.1, 441.4], [445.1, 6.1]], "color": "yellow"}, {"id": "c496e5c3-7716-436d-8e4d-199c85a1360d", "label": "b", "points": [[466.6, 4], [466.6, 441.4], [897.6, 441.4], [897.6, 4]], "color": "cyan"}, {"id": "1b986dee-4206-43eb-920a-688ac95a40f0", "label": "c", "points": [[914.8, 1.8], [914.8, 445.7], [1350.1, 445.7], [1350.1, 1.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Radiography", "start": 9, "end": 20, "id": 4}, {"text": ",", "start": 20, "end": 21, "id": 5}, {"text": "b", "start": 22, "end": 23, "id": 6}, {"text": "gastrografin", "start": 24, "end": 36, "id": 7}, {"text": "enema", "start": 37, "end": 42, "id": 8}, {"text": "examination", "start": 43, "end": 54, "id": 9}, {"text": ",", "start": 54, "end": 55, "id": 10}, {"text": "and", "start": 56, "end": 59, "id": 11}, {"text": "c", "start": 60, "end": 61, "id": 12}, {"text": "computed", "start": 62, "end": 70, "id": 13}, {"text": "tomography", "start": 71, "end": 81, "id": 14}, {"text": "(", "start": 82, "end": 83, "id": 15}, {"text": "CT", "start": 83, "end": 85, "id": 16}, {"text": ")", "start": 85, "end": 86, "id": 17}, {"text": "revealed", "start": 87, "end": 95, "id": 18}, {"text": "stenosis", "start": 96, "end": 104, "id": 19}, {"text": "of", "start": 105, "end": 107, "id": 20}, {"text": "the", "start": 108, "end": 111, "id": 21}, {"text": "descending", "start": 112, "end": 122, "id": 22}, {"text": "colon", "start": 123, "end": 128, "id": 23}, {"text": "(", "start": 129, "end": 130, "id": 24}, {"text": "arrows", "start": 130, "end": 136, "id": 25}, {"text": ")", "start": 136, "end": 137, "id": 26}, {"text": "and", "start": 138, "end": 141, "id": 27}, {"text": "remarkable", "start": 142, "end": 152, "id": 28}, {"text": "distention", "start": 153, "end": 163, "id": 29}, {"text": "on", "start": 164, "end": 166, "id": 30}, {"text": "the", "start": 167, "end": 170, "id": 31}, {"text": "oral", "start": 171, "end": 175, "id": 32}, {"text": "side", "start": 176, "end": 180, "id": 33}, {"text": "of", "start": 181, "end": 183, "id": 34}, {"text": "the", "start": 184, "end": 187, "id": 35}, {"text": "descending", "start": 188, "end": 198, "id": 36}, {"text": "colon", "start": 199, "end": 204, "id": 37}, {"text": ".", "start": 204, "end": 205, "id": 38}, {"text": "Barium", "start": 206, "end": 212, "id": 39}, {"text": "nodules", "start": 213, "end": 220, "id": 40}, {"text": "were", "start": 221, "end": 225, "id": 41}, {"text": "detected", "start": 226, "end": 234, "id": 42}, {"text": "in", "start": 235, "end": 237, "id": 43}, {"text": "the", "start": 238, "end": 241, "id": 44}, {"text": "peritoneal", "start": 242, "end": 252, "id": 45}, {"text": "cavity", "start": 253, "end": 259, "id": 46}, {"text": ",", "start": 259, "end": 260, "id": 47}, {"text": "especially", "start": 261, "end": 271, "id": 48}, {"text": "near", "start": 272, "end": 276, "id": 49}, {"text": "the", "start": 277, "end": 280, "id": 50}, {"text": "anastomosis", "start": 281, "end": 292, "id": 51}]}
{"pdf_hash": "6fef8ba3e8a973129eaeac46c6356daf59e5e2ac", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5 TRIAD-specific changes in cortical neurons of Htt-KI mice. a Electron microscopy revealed numerous cytoplasmic vacuoles (asterisk) despite of normal nucleus (nuc). b Golgi apparatus was also enlarged, while mitochondria (mi) did not expand and the mitochondrial network structure remained. c A larger magnification of mitochondria and Golgi apparatus. d No subcellular organ was involved in the vacuole (asterisk) while ribosome was not confirmed throughout the cell. No autophagic vacuoles were observed at a high magnification. The image was identical to the change of TRIAD in primary cortical neurons, in which vacuoles turned out to be ER [3]. e A large part of neurons at 39 weeks seemed normal, while the space between inner and outer nuclear membranes were slightly dilated. f In 20\u201330% of neurons, invagination of nuclear membrane was observed (arrow). g-1 In such abnormal cells, loss of our nuclear membrane (arrowhead) and cytoplasmic vacuoles (squared area) were frequently observed. g-2 Larger magnification of the squared area is shown. h Mild ER dilatation was also observed in other cells without nuclear invagination. i A few neurons possessed intranuclear fibrils corresponding to nuclear inclusion body. j In the background mice (C57BL/6) at 68 weeks, neurons show no TRIAD-related morphological changes", "width": 1342, "height": 718, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 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{"pdf_hash": "bbca157296e4a12ef1780de30e8283156a4910a4", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "FIG. 4. (A and C) Portion of the MRI coronal cross sections that pass through the deduced locations of the source for the 100-ms component of the auditory-evoked response (dots), for subjects PF and TY, respectively. (B and D) Positions of field measurements and isofield contours for the subjects.", "width": 640, "height": 530, "subcaptions": {"a": [4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 46], "b": [41, 47, 48, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "c": [4, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 43, 46], "d": [43, 47, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "cb4de05c-d3ed-497c-ae71-d904e9e5ce96", "label": "a", "points": [[4.2, 4.4], [4.2, 243], [272.2, 243], [272.2, 4.4]], "color": "yellow"}, {"id": "faa66549-11bc-4344-bf0f-1de714e0ee40", "label": "b", "points": [[298.4, 6.4], [298.4, 245], [638.2, 245], [638.2, 6.4]], "color": "magenta"}, {"id": "5b0ca97e-06b6-42df-88c9-0c206d9e1655", "label": "c", "points": [[7.2, 253.1], [7.2, 499.8], [272.2, 499.8], [272.2, 253.1]], "color": "cyan"}, {"id": "456b7332-5ae9-49c8-aa4e-870b94f7ff6a", "label": "d", "points": [[300.5, 251.1], [300.5, 503.9], [632.1, 503.9], [632.1, 251.1]], "color": "springgreen"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": "and", "start": 11, "end": 14, "id": 6}, {"text": "C", "start": 15, "end": 16, "id": 7}, {"text": ")", "start": 16, "end": 17, "id": 8}, {"text": "Portion", "start": 18, "end": 25, "id": 9}, {"text": "of", "start": 26, "end": 28, "id": 10}, {"text": "the", "start": 29, "end": 32, "id": 11}, {"text": "MRI", "start": 33, "end": 36, "id": 12}, {"text": "coronal", "start": 37, "end": 44, "id": 13}, {"text": "cross", "start": 45, "end": 50, "id": 14}, {"text": "sections", "start": 51, "end": 59, "id": 15}, {"text": "that", "start": 60, "end": 64, "id": 16}, {"text": "pass", "start": 65, "end": 69, "id": 17}, {"text": "through", "start": 70, "end": 77, "id": 18}, {"text": "the", "start": 78, "end": 81, "id": 19}, {"text": "deduced", "start": 82, "end": 89, "id": 20}, {"text": "locations", "start": 90, "end": 99, "id": 21}, {"text": "of", "start": 100, "end": 102, "id": 22}, {"text": "the", "start": 103, "end": 106, "id": 23}, {"text": "source", "start": 107, "end": 113, "id": 24}, {"text": "for", "start": 114, "end": 117, "id": 25}, {"text": "the", "start": 118, "end": 121, "id": 26}, {"text": "100-ms", "start": 122, "end": 128, "id": 27}, {"text": "component", "start": 129, "end": 138, "id": 28}, {"text": "of", "start": 139, "end": 141, "id": 29}, {"text": "the", "start": 142, "end": 145, "id": 30}, {"text": "auditory", "start": 146, "end": 154, "id": 31}, {"text": "-", "start": 154, "end": 155, "id": 32}, {"text": "evoked", "start": 155, "end": 161, "id": 33}, {"text": "response", "start": 162, "end": 170, "id": 34}, {"text": "(", "start": 171, "end": 172, "id": 35}, {"text": "dots", "start": 172, "end": 176, "id": 36}, {"text": ")", "start": 176, "end": 177, "id": 37}, {"text": ",", "start": 177, "end": 178, "id": 38}, {"text": "for", "start": 179, "end": 182, "id": 39}, {"text": "subjects", "start": 183, "end": 191, "id": 40}, {"text": "PF", "start": 192, "end": 194, "id": 41}, {"text": "and", "start": 195, "end": 198, "id": 42}, {"text": "TY", "start": 199, "end": 201, "id": 43}, {"text": ",", "start": 201, "end": 202, "id": 44}, {"text": "respectively", "start": 203, "end": 215, "id": 45}, {"text": ".", "start": 215, "end": 216, "id": 46}, {"text": "(", "start": 217, "end": 218, "id": 47}, {"text": "B", "start": 218, "end": 219, "id": 48}, {"text": "and", "start": 220, "end": 223, "id": 49}, {"text": "D", "start": 224, "end": 225, "id": 50}, {"text": ")", "start": 225, "end": 226, "id": 51}, {"text": "Positions", "start": 227, "end": 236, "id": 52}, {"text": "of", "start": 237, "end": 239, "id": 53}, {"text": "field", "start": 240, "end": 245, "id": 54}, {"text": "measurements", "start": 246, "end": 258, "id": 55}, {"text": "and", "start": 259, "end": 262, "id": 56}, {"text": "isofield", "start": 263, "end": 271, "id": 57}, {"text": "contours", "start": 272, "end": 280, "id": 58}, {"text": "for", "start": 281, "end": 284, "id": 59}, {"text": "the", "start": 285, "end": 288, "id": 60}, {"text": "subjects", "start": 289, "end": 297, "id": 61}, {"text": ".", "start": 297, "end": 298, "id": 62}]}
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{"pdf_hash": "6d5fc48b912cca5f4d23cf9f08029a86bd2d2c1e", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Preoperative and postoperative 1-year chest X-ray. (A) Severe cardiomegaly is shown. (B) Cardiomegaly is improved after the operation.", "width": 1008, "height": 498, "subcaptions": {"a": [4, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [6, 7, 8, 9, 10, 11, 12, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "692401da-da90-4400-85ea-6610562aceed", "label": "a", "points": [[4.8, 2.9], [4.8, 493.4], [487.3, 493.4], [487.3, 2.9]], "color": "yellow"}, {"id": "da46440a-e1f1-485a-b647-b7df45c3c771", "label": "b", "points": [[496.9, 4.5], [496.9, 491.8], [974.6, 491.8], [974.6, 4.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Preoperative", "start": 8, "end": 20, "id": 4}, {"text": "and", "start": 21, "end": 24, "id": 5}, {"text": "postoperative", "start": 25, "end": 38, "id": 6}, {"text": "1-year", "start": 39, "end": 45, "id": 7}, {"text": "chest", "start": 46, "end": 51, "id": 8}, {"text": "X", "start": 52, "end": 53, "id": 9}, {"text": "-", "start": 53, "end": 54, "id": 10}, {"text": "ray", "start": 54, "end": 57, "id": 11}, {"text": ".", "start": 57, "end": 58, "id": 12}, {"text": "(", "start": 59, "end": 60, "id": 13}, {"text": "A", "start": 60, "end": 61, "id": 14}, {"text": ")", "start": 61, "end": 62, "id": 15}, {"text": "Severe", "start": 63, "end": 69, "id": 16}, {"text": "cardiomegaly", "start": 70, "end": 82, "id": 17}, {"text": "is", "start": 83, "end": 85, "id": 18}, {"text": "shown", "start": 86, "end": 91, "id": 19}, {"text": ".", "start": 91, "end": 92, "id": 20}, {"text": "(", "start": 93, "end": 94, "id": 21}, {"text": "B", "start": 94, "end": 95, "id": 22}, {"text": ")", "start": 95, "end": 96, "id": 23}, {"text": "Cardiomegaly", "start": 97, "end": 109, "id": 24}, {"text": "is", "start": 110, "end": 112, "id": 25}, {"text": "improved", "start": 113, "end": 121, "id": 26}, {"text": "after", "start": 122, "end": 127, "id": 27}, {"text": "the", "start": 128, "end": 131, "id": 28}, {"text": "operation", "start": 132, "end": 141, "id": 29}, {"text": ".", "start": 141, "end": 142, "id": 30}]}
{"pdf_hash": "f8856969519250ac1617eaa9424e2e6bd421fe53", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. The primary tumor sampled by endobronchial ultrasound fine\u2011needle aspiration. (A) Epithelial and spindle\u2011shaped tumor cells showed alveolar growth solid. (B) Immunohistochemical examination showed positive for c\u2011kit. Magnification, x200.", "width": 1098, "height": 410, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "40305420-67a7-4f2a-8240-76d684b4eb4f", "label": "a", "points": [[33.8, 6.9], [33.8, 378.2], [547.3, 378.2], [547.3, 6.9]], "color": "yellow"}, {"id": "f94ae476-19ca-48f4-a420-c7ddd2251f99", "label": "b", "points": [[554.2, 5.2], [554.2, 378.2], [1076.3, 378.2], [1076.3, 5.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "The", "start": 10, "end": 13, "id": 3}, {"text": "primary", "start": 14, "end": 21, "id": 4}, {"text": "tumor", "start": 22, "end": 27, "id": 5}, {"text": "sampled", "start": 28, "end": 35, "id": 6}, {"text": "by", "start": 36, "end": 38, "id": 7}, {"text": "endobronchial", "start": 39, "end": 52, "id": 8}, {"text": "ultrasound", "start": 53, "end": 63, "id": 9}, {"text": "fine\u2011needle", "start": 64, "end": 75, "id": 10}, {"text": "aspiration", "start": 76, "end": 86, "id": 11}, {"text": ".", "start": 86, "end": 87, "id": 12}, {"text": "(", "start": 88, "end": 89, "id": 13}, {"text": "A", "start": 89, "end": 90, "id": 14}, {"text": ")", "start": 90, "end": 91, "id": 15}, {"text": "Epithelial", "start": 92, "end": 102, "id": 16}, {"text": "and", "start": 103, "end": 106, "id": 17}, {"text": "spindle\u2011shaped", "start": 107, "end": 121, "id": 18}, {"text": "tumor", "start": 122, "end": 127, "id": 19}, {"text": "cells", "start": 128, "end": 133, "id": 20}, {"text": "showed", "start": 134, "end": 140, "id": 21}, {"text": "alveolar", "start": 141, "end": 149, "id": 22}, {"text": "growth", "start": 150, "end": 156, "id": 23}, {"text": "solid", "start": 157, "end": 162, "id": 24}, {"text": ".", "start": 162, "end": 163, "id": 25}, {"text": "(", "start": 164, "end": 165, "id": 26}, {"text": "B", "start": 165, "end": 166, "id": 27}, {"text": ")", "start": 166, "end": 167, "id": 28}, {"text": "Immunohistochemical", "start": 168, "end": 187, "id": 29}, {"text": "examination", "start": 188, "end": 199, "id": 30}, {"text": "showed", "start": 200, "end": 206, "id": 31}, {"text": "positive", "start": 207, "end": 215, "id": 32}, {"text": "for", "start": 216, "end": 219, "id": 33}, {"text": "c\u2011kit", "start": 220, "end": 225, "id": 34}, {"text": ".", "start": 225, "end": 226, "id": 35}, {"text": "Magnification", "start": 227, "end": 240, "id": 36}, {"text": ",", "start": 240, "end": 241, "id": 37}, {"text": "x200", "start": 242, "end": 246, "id": 38}, {"text": ".", "start": 246, "end": 247, "id": 39}]}
{"pdf_hash": "cf4f2cf13f1b4205853c9bf5f3d75bde2c489cfd", "fig_key": "Figure4", "fig_uri": "2-Figure4-1.png", "text": "Fig. 4. Postoperative brain MRI. A : On postoperative day 1, brain MRI shows a 18\u00d718 mm sized mass compressing the adjacent structures in the interpeduncular cistern. B : At 21 months postoperatively, most of the thrombosed aneurysm has disappeared and the interpeduncular cistern is clearly observed. MRI : magnetic resonance imaging.", "width": 630, "height": 378, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53]}, "subfigures": [{"id": "109e09da-a402-4117-ba23-4da4caf4f2b0", "label": "a", "points": [[1.5, 39], [1.5, 359], [310.5, 359], [310.5, 39]], "color": "yellow"}, {"id": "53fc9c8b-5735-4585-909f-b32077a40185", "label": "b", "points": [[319.5, 38], [319.5, 360], [629.5, 360], [629.5, 38]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Postoperative", "start": 8, "end": 21, "id": 4}, {"text": "brain", "start": 22, "end": 27, "id": 5}, {"text": "MRI", "start": 28, "end": 31, "id": 6}, {"text": ".", "start": 31, "end": 32, "id": 7}, {"text": "A", "start": 33, "end": 34, "id": 8}, {"text": ":", "start": 35, "end": 36, "id": 9}, {"text": "On", "start": 37, "end": 39, "id": 10}, {"text": "postoperative", "start": 40, "end": 53, "id": 11}, {"text": "day", "start": 54, "end": 57, "id": 12}, {"text": "1", "start": 58, "end": 59, "id": 13}, {"text": ",", "start": 59, "end": 60, "id": 14}, {"text": "brain", "start": 61, "end": 66, "id": 15}, {"text": "MRI", "start": 67, "end": 70, "id": 16}, {"text": "shows", "start": 71, "end": 76, "id": 17}, {"text": "a", "start": 77, "end": 78, "id": 18}, {"text": "18\u00d718", "start": 79, "end": 84, "id": 19}, {"text": "mm", "start": 85, "end": 87, "id": 20}, {"text": "sized", "start": 88, "end": 93, "id": 21}, {"text": "mass", "start": 94, "end": 98, "id": 22}, {"text": "compressing", "start": 99, "end": 110, "id": 23}, {"text": "the", "start": 111, "end": 114, "id": 24}, {"text": "adjacent", "start": 115, "end": 123, "id": 25}, {"text": "structures", "start": 124, "end": 134, "id": 26}, {"text": "in", "start": 135, "end": 137, "id": 27}, {"text": "the", "start": 138, "end": 141, "id": 28}, {"text": "interpeduncular", "start": 142, "end": 157, "id": 29}, {"text": "cistern", "start": 158, "end": 165, "id": 30}, {"text": ".", "start": 165, "end": 166, "id": 31}, {"text": "B", "start": 167, "end": 168, "id": 32}, {"text": ":", "start": 169, "end": 170, "id": 33}, {"text": "At", "start": 171, "end": 173, "id": 34}, {"text": "21", "start": 174, "end": 176, "id": 35}, {"text": "months", "start": 177, "end": 183, "id": 36}, {"text": "postoperatively", "start": 184, "end": 199, "id": 37}, {"text": ",", "start": 199, "end": 200, "id": 38}, {"text": "most", "start": 201, "end": 205, "id": 39}, {"text": "of", "start": 206, "end": 208, "id": 40}, {"text": "the", "start": 209, "end": 212, "id": 41}, {"text": "thrombosed", "start": 213, "end": 223, "id": 42}, {"text": "aneurysm", "start": 224, "end": 232, "id": 43}, {"text": "has", "start": 233, "end": 236, "id": 44}, {"text": "disappeared", "start": 237, "end": 248, "id": 45}, {"text": "and", "start": 249, "end": 252, "id": 46}, {"text": "the", "start": 253, "end": 256, "id": 47}, {"text": "interpeduncular", "start": 257, "end": 272, "id": 48}, {"text": "cistern", "start": 273, "end": 280, "id": 49}, {"text": "is", "start": 281, "end": 283, "id": 50}, {"text": "clearly", "start": 284, "end": 291, "id": 51}, {"text": "observed", "start": 292, "end": 300, "id": 52}, {"text": ".", "start": 300, "end": 301, "id": 53}, {"text": "MRI", "start": 302, "end": 305, "id": 54}, {"text": ":", "start": 306, "end": 307, "id": 55}, {"text": "magnetic", "start": 308, "end": 316, "id": 56}, {"text": "resonance", "start": 317, "end": 326, "id": 57}, {"text": "imaging", "start": 327, "end": 334, "id": 58}, {"text": ".", "start": 334, "end": 335, "id": 59}]}
{"pdf_hash": "c9bd2b7bce872e7ebb40f92d18adebc7c66b2b28", "fig_key": "Figure7", "fig_uri": "10-Figure7-1.png", "text": "Figure 7. Abnormal accumulation of interneurons in LI and SPP in Cdk5 \u00c0/\u00c0 and reeler mice, respectively. E18.5 coronal sections, of Cdk5 \u00c0/\u00c0 and reeler forebrain, stained with Nissl and labeled with antibodies against CB and LHX6. In the Cdk5 \u00c0/\u00c0 cortex, LI is wide and cell dense (A) and packed with numerous CB \u00fe (B) and LHX6 \u00fe (C) cells. In reeler mice, SPP, containing undivided (or mixed) LI and SP cells, is a thick cortical layer (D) containing an abundance of CB \u00fe (E) and LHX6 \u00fe (F) cells. Dashed lines represent the border between LI or SPP and the rest of the developing cortical layers. 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{"pdf_hash": "b08a0539d32e6df0a93eb611aea4fa314424b126", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Upper endoscopy. Upper endoscopy showed an elongated columnar epithelium from the squamocolumnar junction indicating BE (a) and a type 0-IIa + IIc elevated lesion adjacent to the BE lesion (b)", "width": 856, "height": 394, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "afe2dd2e-82e9-442d-953a-257e071d0146", "label": "a", "points": [[32.5, 14.9], [32.5, 361.1], [426, 361.1], [426, 14.9]], "color": "yellow"}, {"id": "96a57bb4-8033-4a06-8dd7-305b38bebc27", "label": "b", "points": [[428.7, 18.9], [428.7, 361.1], [819.5, 361.1], [819.5, 18.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Upper", "start": 7, "end": 12, "id": 3}, {"text": "endoscopy", "start": 13, "end": 22, "id": 4}, {"text": ".", "start": 22, "end": 23, "id": 5}, {"text": "Upper", "start": 24, "end": 29, "id": 6}, {"text": "endoscopy", "start": 30, "end": 39, "id": 7}, {"text": "showed", "start": 40, "end": 46, "id": 8}, {"text": "an", "start": 47, "end": 49, "id": 9}, {"text": "elongated", "start": 50, "end": 59, "id": 10}, {"text": "columnar", "start": 60, "end": 68, "id": 11}, {"text": "epithelium", "start": 69, "end": 79, "id": 12}, {"text": "from", "start": 80, "end": 84, "id": 13}, {"text": "the", "start": 85, "end": 88, "id": 14}, {"text": "squamocolumnar", "start": 89, "end": 103, "id": 15}, {"text": "junction", "start": 104, "end": 112, "id": 16}, {"text": "indicating", "start": 113, "end": 123, "id": 17}, {"text": "BE", "start": 124, "end": 126, "id": 18}, {"text": "(", "start": 127, "end": 128, "id": 19}, {"text": "a", "start": 128, "end": 129, "id": 20}, {"text": ")", "start": 129, "end": 130, "id": 21}, {"text": "and", "start": 131, "end": 134, "id": 22}, {"text": "a", "start": 135, "end": 136, "id": 23}, {"text": "type", "start": 137, "end": 141, "id": 24}, {"text": "0-IIa", "start": 142, "end": 147, "id": 25}, {"text": "+", "start": 148, "end": 149, "id": 26}, {"text": "IIc", "start": 150, "end": 153, "id": 27}, {"text": "elevated", "start": 154, "end": 162, "id": 28}, {"text": "lesion", "start": 163, "end": 169, "id": 29}, {"text": "adjacent", "start": 170, "end": 178, "id": 30}, {"text": "to", "start": 179, "end": 181, "id": 31}, {"text": "the", "start": 182, "end": 185, "id": 32}, {"text": "BE", "start": 186, "end": 188, "id": 33}, {"text": "lesion", "start": 189, "end": 195, "id": 34}, {"text": "(", "start": 196, "end": 197, "id": 35}, {"text": "b", "start": 197, "end": 198, "id": 36}, {"text": ")", "start": 198, "end": 199, "id": 37}]}
{"pdf_hash": "f2d2b77ca0725afac2df5f7e00fb0fef0e2718f7", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. PrP C distribution in a P37 opossum brain. (A-B) Coronal sections in the caudal diencephalon from a P37 opossum were stained for PrP C in the thalamus (Th) and in the parenchyma of the hippocampus. (A) In the ventral thalamus, a strong IR was observed in the reticular nucleus (Rt) and in the nucleus reuniens (Re). No IR was observed in the optic tract (Ot). In the hypothalamic area (H) the immunoreactivity was lower than in the thalamus. (B) A strong PrP C signal was observed in the stratum oriens (or) and in the stratum radiatum (rad) of the hippocampus. A low PrP C immunoreactivity was observed in the hilar region (h), while the pyramidal (pyr) and granule (gr) cell layers of the CA1-CA3 and DG were devoid of immunostaining (Bars: 1 mm). doi:10.1371/journal.pone.0050370.g004", "width": 1072, "height": 476, "subcaptions": {"a": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102], "b": [103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168]}, "subfigures": [{"id": "55c695c6-e030-418f-b125-df4b59774347", "label": "a", "points": [[-0.8, 6.5], [-0.8, 438.3], [595.3, 438.3], [595.3, 6.5]], 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{"pdf_hash": "87c074bbcf5a13b69212079a11505102df2b9b6d", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4. Sagittal unenhanced CT scan: the same heterogenous intracanal mass is found (black arrow) with erosions of C2 cortical bone and several osteocondensent zones (white circle). Enlargement of the medullary canal.", "width": 1120, "height": 664, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "53d52170-1817-41b4-8a80-ded6f3ac095e", "label": "a", "points": [[31, 0], [31, 629.9], [575.9, 629.9], [575.9, 0]], "color": "yellow"}, {"id": "0bfdc032-fa31-42f1-a9de-fcfef5d07cf2", "label": "b", "points": [[586.6, 0], [586.6, 631.7], [1085.5, 631.7], [1085.5, 0]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Sagittal", "start": 10, "end": 18, "id": 3}, {"text": "unenhanced", "start": 19, "end": 29, "id": 4}, {"text": "CT", "start": 30, "end": 32, "id": 5}, {"text": "scan", "start": 33, "end": 37, "id": 6}, {"text": ":", "start": 37, "end": 38, "id": 7}, {"text": "the", "start": 39, "end": 42, "id": 8}, {"text": "same", "start": 43, "end": 47, "id": 9}, {"text": "heterogenous", "start": 48, "end": 60, "id": 10}, {"text": "intracanal", "start": 61, "end": 71, "id": 11}, {"text": "mass", "start": 72, "end": 76, "id": 12}, {"text": "is", "start": 77, "end": 79, "id": 13}, {"text": "found", "start": 80, "end": 85, "id": 14}, {"text": "(", "start": 86, "end": 87, "id": 15}, {"text": "black", "start": 87, "end": 92, "id": 16}, {"text": "arrow", "start": 93, "end": 98, "id": 17}, {"text": ")", "start": 98, "end": 99, "id": 18}, {"text": "with", "start": 100, "end": 104, "id": 19}, {"text": "erosions", "start": 105, "end": 113, "id": 20}, {"text": "of", "start": 114, "end": 116, "id": 21}, {"text": "C2", "start": 117, "end": 119, "id": 22}, {"text": "cortical", "start": 120, "end": 128, "id": 23}, {"text": "bone", "start": 129, "end": 133, "id": 24}, {"text": "and", "start": 134, "end": 137, "id": 25}, {"text": "several", "start": 138, "end": 145, "id": 26}, {"text": "osteocondensent", "start": 146, "end": 161, "id": 27}, {"text": "zones", "start": 162, "end": 167, "id": 28}, {"text": "(", "start": 168, "end": 169, "id": 29}, {"text": "white", "start": 169, "end": 174, "id": 30}, {"text": "circle", "start": 175, "end": 181, "id": 31}, {"text": ")", "start": 181, "end": 182, "id": 32}, {"text": ".", "start": 182, "end": 183, "id": 33}, {"text": "Enlargement", "start": 184, "end": 195, "id": 34}, {"text": "of", "start": 196, "end": 198, "id": 35}, {"text": "the", "start": 199, "end": 202, "id": 36}, {"text": "medullary", "start": 203, "end": 212, "id": 37}, {"text": "canal", "start": 213, "end": 218, "id": 38}, {"text": ".", "start": 218, "end": 219, "id": 39}]}
{"pdf_hash": "8436e631cc662f75ffb2b928d61ac7a5b66ddad1", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2 Sagittal short tau inversion recovery images of the lower spine of two different patients. (A) At level L5\u2013 S1, disc space narrowing with a low signal intensity of the disc is seen, with concomitant high signal intensity of the endplates of L4 and L5 (arrows). This is consistent with disc degeneration with Modic endplate changes. (B) At L5\u2013S1, disc degeneration is present without endplate changes; the disc space narrowing is less pronounced than in (A). At level L3\u20134, however, the anterior corners of the endplates show focal high signal intensity despite a normal disc (arrows). 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{"pdf_hash": "2fb8c2e05054ca8195c670d63291cb69323ed0a2", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 Effusion in the biceps tendon sheath. (GT=greater tubercle, LT= lesser tubercle). Transverse (a, b) and longitudinal (c) ultrasound images of the long head of the biceps tendon (curved arrow) in its position in the bicipital groove are shown. Already before injection of fluid, a small edge (2 mm) of anechoic collection (joint effusion) is seen in the tendon sheath (arrowheads, a). After injection (b, c), no conspicuous increase of anechoic collection is detectable. d Correlative transverse trueFISP MR image after injection of fluid", "width": 902, "height": 830, "subcaptions": {"a": [21, 22, 23, 26, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87], "b": [21, 22, 25, 26, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 88, 89, 90, 91, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104], "c": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 88, 89, 90, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104], "d": [105, 106, 107, 108, 109, 110, 111, 112, 113, 114]}, "subfigures": [{"id": "e1e24203-1c64-4c36-9034-3a508f5b5269", "label": "a", "points": [[45.8, 31.8], [45.8, 419.4], [460.5, 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{"pdf_hash": "17dd8a457c9f2f7cecd1a48b1eb82f6bd36a16da", "fig_key": "Figure4", "fig_uri": "9-Figure4-1.png", "text": "Figure 4. Local tumor recurrence after transarterial chemoembolization (TACE) in a 63-year-old woman with hepatocellular carcinoma. (A) Enhanced magnetic resonance (MR) images show a 3.5-cm-sized hypervascular tumor at segment 6 of the right hepatic lobe (arrow). (B) Spot radiograph obtained after TACE shows a tumor stain (arrow) with prominent portal veins in the embolized area (arrowheads). (C) Cone-beam computed tomography (CT) scan obtained immediately after TACE shows dense iodized oil accumulation in the tumor (arrow). The anterolateral tumor aspect was not completely covered by parenchymal iodized oil deposition (arrowheads), which was classified as grade B. (D) Unenhanced CT scan obtained 1 month after TACE shows dense iodized oil accumulation in the tumor (arrow). 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{"pdf_hash": "8bb28626313c0a2147f3b509e8f6b485c5fb26ba", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "FIGURE 6 Imaging melanophores. Comparison between brightfield (A) and two-photon excitation fluorescence (B) images of a melanophore revealed that melanosomes are observed under two-photon excitation. The excitation wavelength was 780 nm. (Scale bars, 5 mm).", "width": 666, "height": 276, "subcaptions": {"a": [32, 33, 34, 7, 8, 9, 10, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34]}, "subfigures": [{"id": "a83b8e67-1df6-4929-ba8e-8d6188bb9d5b", "label": "a", "points": [[337.2, 242], [337.2, -1.1], [1.6, -1.1], [1.6, 242]], "color": "yellow"}, {"id": "c0779e62-d0ed-46d9-8c0f-6539fbe3d482", "label": "b", "points": [[343.5, 0], [343.5, 236.7], [663.4, 236.7], [663.4, 0]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": "Imaging", "start": 9, "end": 16, "id": 2}, {"text": "melanophores", "start": 17, "end": 29, "id": 3}, {"text": ".", "start": 29, "end": 30, "id": 4}, {"text": "Comparison", "start": 31, "end": 41, "id": 5}, {"text": "between", "start": 42, "end": 49, "id": 6}, {"text": "brightfield", "start": 50, "end": 61, "id": 7}, {"text": "(", "start": 62, "end": 63, "id": 8}, {"text": "A", "start": 63, "end": 64, "id": 9}, {"text": ")", "start": 64, "end": 65, "id": 10}, {"text": "and", "start": 66, "end": 69, "id": 11}, {"text": "two", "start": 70, "end": 73, "id": 12}, {"text": "-", "start": 73, "end": 74, "id": 13}, {"text": "photon", "start": 74, "end": 80, "id": 14}, {"text": "excitation", "start": 81, "end": 91, "id": 15}, {"text": "fluorescence", "start": 92, "end": 104, "id": 16}, {"text": "(", "start": 105, "end": 106, "id": 17}, {"text": "B", "start": 106, "end": 107, "id": 18}, {"text": ")", "start": 107, "end": 108, "id": 19}, {"text": "images", "start": 109, "end": 115, "id": 20}, {"text": "of", "start": 116, "end": 118, "id": 21}, {"text": "a", "start": 119, "end": 120, "id": 22}, {"text": "melanophore", "start": 121, "end": 132, "id": 23}, {"text": "revealed", "start": 133, "end": 141, "id": 24}, {"text": "that", "start": 142, "end": 146, "id": 25}, {"text": "melanosomes", "start": 147, "end": 158, "id": 26}, {"text": "are", "start": 159, "end": 162, "id": 27}, {"text": "observed", "start": 163, "end": 171, "id": 28}, {"text": "under", "start": 172, "end": 177, "id": 29}, {"text": "two", "start": 178, "end": 181, "id": 30}, {"text": "-", "start": 181, "end": 182, "id": 31}, {"text": "photon", "start": 182, "end": 188, "id": 32}, {"text": "excitation", "start": 189, "end": 199, "id": 33}, {"text": ".", "start": 199, "end": 200, "id": 34}, {"text": "The", "start": 201, "end": 204, "id": 35}, {"text": "excitation", "start": 205, "end": 215, "id": 36}, {"text": "wavelength", "start": 216, "end": 226, "id": 37}, {"text": "was", "start": 227, "end": 230, "id": 38}, {"text": "780", "start": 231, "end": 234, "id": 39}, {"text": "nm", "start": 235, "end": 237, "id": 40}, {"text": ".", "start": 237, "end": 238, "id": 41}, {"text": "(", "start": 239, "end": 240, "id": 42}, {"text": "Scale", "start": 240, "end": 245, "id": 43}, {"text": "bars", "start": 246, "end": 250, "id": 44}, {"text": ",", "start": 250, "end": 251, "id": 45}, {"text": "5", "start": 252, "end": 253, "id": 46}, {"text": "mm", "start": 254, "end": 256, "id": 47}, {"text": ")", "start": 256, "end": 257, "id": 48}, {"text": ".", "start": 257, "end": 258, "id": 49}]}
{"pdf_hash": "f2e2a107e59ae19b5879773fa993e38fd76f84e7", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3 - Schwannoma of V2, case P11. Coronal (A) and axial CT (B) scans showing considerable deformation of the splanchno and neurocranium on the right side. A mass (74 x 65 x 61 mm) arising from V2 in the pterygopalatine fossa with bulky extension to the ITF, cheek, and middle cranial fossa via the foramen rotundum, which is extremely enlarged (long arrow) \u2013 see side difference. The schwannoma pushed the posterior wall of the maxillary sinus forward (short arrow) and the pterygoid process backward (dashed arrow) \u2013 also see side differences. (C) An axial T1-weighted MRI scan with gadolinium contrast showing the margin between the tumor and soft tissue. (D) A sagittal T2-weighted MRI scan showing that the tumor is pressing on the orbital apex via the infraorbital fissure (long arrow) with an intracranial portion (24 x 21 x 20 mm) in the middle cranial fossa (dotted line). Postoperative T2-weighted MRI scans in the sagittal (E) and axial (F) planes demonstrate no evidence of disease 21 months after surgery. A nasoseptal flap (long arrow) was used to cover exposed dura mater of the middle cranial fossa, although no clear leakage of cerebrospinal fluid was observed intraoperatively. 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{"pdf_hash": "050d3afcc181d34830a54ccaf7d7f88197bc56af", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. The findings of magnetic resonance imaging are consistent with acute disseminated encephalomyelitis (A and B) and then suggestive of aggressive tumor (C). A, Initial fluid-attenuated inversion recovery magnetic resonance imaging demonstrates involvement of the left internal capsule and caudate. B, Subsequent fluid-attenuated inversion recovery magnetic resonance imaging 3 months later demonstrates increased involvement. 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{"pdf_hash": "a6b7c284e3761f3ff5e6651968747a2c7af85016", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Preoperative CT images: (A) Transverse image of the 5th lumbar vertebra and (B) sagittal image indicating a large mass with an irregular surface (12 \u00d7 8 \u00d7 6 cm in size) extending from the cecum. (C) Photograph of the surgically resected area showing the main tumor and multiple disseminated masses (arrows) in the omentum. 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{"pdf_hash": "76e985e6066e4db14c8a96f3a505c1d379ac404f", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. A 59-year-old woman with known right breast cancer (4-o\u2019clock position) who underwent preoperative breast magnetic resonance imaging (MRI). (A) Subtraction axial MR image shows unexpected oval shaped enhancing lesion (arrow) at 3-o\u2019clock position in the right breast. It was classified as malignant. (B) On second-look ultrasound, 0.7 cm sized, oval, ill defined, and hypoechoic lesion was found at the identical location. Sonographic findings suggest BI-RADS 4C and pathologic result was invasive ductal carcinoma.", "width": 1272, "height": 458, "subcaptions": {"a": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "b": [58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100]}, "subfigures": [{"id": "f183a585-4836-4de1-8e3b-2f56cd4c9332", "label": "a", "points": [[7, 114.5], [7, 426], [674.2, 426], [674.2, 114.5]], "color": "yellow"}, {"id": "b737a891-1a78-4b8e-8238-e3c4eba6d3cd", "label": "b", "points": [[684.3, 8], [684.3, 422], [1244.9, 422], [1244.9, 8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "59-year", "start": 12, "end": 19, 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{"pdf_hash": "b52fce7c0bc6a9846c854800ee439ad0fd85cd84", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Hematoxylin-eosin (HE) staining in gray matter of injured spinal cord specimens on the third day postoperatively. (a) Control group: round swollen neurons (white arrow), nuclear concentration, nuclear fragmentation and a great deal of neutrophil infiltration (white arrowhead) were seen. (b) Soluble complement receptor type 1 group. A little neutrophil infiltration in reparative tissue was seen, whereas a lot of polygon-shaped neurons (arrow) were observed (HE, magnification: \u00c2 200).", "width": 662, "height": 1010, "subcaptions": {"a": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88]}, "subfigures": [{"id": "b6cf3272-599e-4c06-8062-f98a0bdd543a", "label": "a", "points": [[3.7, 5.1], [3.7, 471.5], [655.2, 471.5], [655.2, 5.1]], "color": "yellow"}, {"id": "a1f16d54-c1f7-4efd-b739-44a8300d1451", "label": "b", "points": [[4.7, 495.5], [4.7, 981.8], [655.2, 981.8], [655.2, 495.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Hematoxylin", "start": 9, "end": 20, "id": 2}, {"text": "-", "start": 20, "end": 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{"pdf_hash": "1fc0f9ca548b634f6a59b541db02e69c5767a55d", "fig_key": "Figure14", "fig_uri": "8-Figure14-1.png", "text": "FIG. 14. Transmission ultrasound images of a dense breast quantitative breast density (QBD = 62.4%). Top row, speed of sound (SOS). L to R: coronal, axial, sagittal. Middle row, segmentation with skin. Bottom row, corresponding total breast volume. There is clear correlation between the total breast volume, the segmentation, and the high-speed tissue. 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{"pdf_hash": "a280695a9a9f0a9fb477d7fb0e40b70741518584", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Chest X-ray (a) and computed tomography (b) images obtained at the second admission. Superior mediastinum expansion was recognized (a). The lymph node of #4R exhibited swelling, and a low-density area was recognized inside this lymph node (b).", "width": 946, "height": 420, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "42e09170-641b-4db3-938a-b75646c6a538", "label": "a", "points": [[7.7, 0.5], [7.7, 378.6], [399.3, 378.6], [399.3, 0.5]], "color": "yellow"}, {"id": "d3b19eca-bead-4d52-88a0-1973290ff0b8", "label": "b", "points": [[412.7, 0.5], [412.7, 383.1], [940.3, 383.1], [940.3, 0.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Chest", "start": 10, "end": 15, "id": 3}, {"text": "X", "start": 16, "end": 17, "id": 4}, {"text": "-", "start": 17, "end": 18, "id": 5}, {"text": "ray", "start": 18, "end": 21, "id": 6}, {"text": "(", "start": 22, "end": 23, "id": 7}, {"text": "a", "start": 23, "end": 24, "id": 8}, {"text": ")", "start": 24, "end": 25, "id": 9}, {"text": "and", "start": 26, "end": 29, "id": 10}, {"text": "computed", "start": 30, "end": 38, "id": 11}, {"text": "tomography", "start": 39, "end": 49, "id": 12}, {"text": "(", "start": 50, "end": 51, "id": 13}, {"text": "b", "start": 51, "end": 52, "id": 14}, {"text": ")", "start": 52, "end": 53, "id": 15}, {"text": "images", "start": 54, "end": 60, "id": 16}, {"text": "obtained", "start": 61, "end": 69, "id": 17}, {"text": "at", "start": 70, "end": 72, "id": 18}, {"text": "the", "start": 73, "end": 76, "id": 19}, {"text": "second", "start": 77, "end": 83, "id": 20}, {"text": "admission", "start": 84, "end": 93, "id": 21}, {"text": ".", "start": 93, "end": 94, "id": 22}, {"text": "Superior", "start": 95, "end": 103, "id": 23}, {"text": "mediastinum", "start": 104, "end": 115, "id": 24}, {"text": "expansion", "start": 116, "end": 125, "id": 25}, {"text": "was", "start": 126, "end": 129, "id": 26}, {"text": "recognized", "start": 130, "end": 140, "id": 27}, {"text": "(", "start": 141, "end": 142, "id": 28}, {"text": "a", "start": 142, "end": 143, "id": 29}, {"text": ")", "start": 143, "end": 144, "id": 30}, {"text": ".", "start": 144, "end": 145, "id": 31}, {"text": "The", "start": 146, "end": 149, "id": 32}, {"text": "lymph", "start": 150, "end": 155, "id": 33}, {"text": "node", "start": 156, "end": 160, "id": 34}, {"text": "of", "start": 161, "end": 163, "id": 35}, {"text": "#", "start": 164, "end": 165, "id": 36}, {"text": "4R", "start": 165, "end": 167, "id": 37}, {"text": "exhibited", "start": 168, "end": 177, "id": 38}, {"text": "swelling", "start": 178, "end": 186, "id": 39}, {"text": ",", "start": 186, "end": 187, "id": 40}, {"text": "and", "start": 188, "end": 191, "id": 41}, {"text": "a", "start": 192, "end": 193, "id": 42}, {"text": "low", "start": 194, "end": 197, "id": 43}, {"text": "-", "start": 197, "end": 198, "id": 44}, {"text": "density", "start": 198, "end": 205, "id": 45}, {"text": "area", "start": 206, "end": 210, "id": 46}, {"text": "was", "start": 211, "end": 214, "id": 47}, {"text": "recognized", "start": 215, "end": 225, "id": 48}, {"text": "inside", "start": 226, "end": 232, "id": 49}, {"text": "this", "start": 233, "end": 237, "id": 50}, {"text": "lymph", "start": 238, "end": 243, "id": 51}, {"text": "node", "start": 244, "end": 248, "id": 52}, {"text": "(", "start": 249, "end": 250, "id": 53}, {"text": "b", "start": 250, "end": 251, "id": 54}, {"text": ")", "start": 251, "end": 252, "id": 55}, {"text": ".", "start": 252, "end": 253, "id": 56}]}
{"pdf_hash": "81e2c87eda4bb5bd08c11d9af73a63e6c4262aed", "fig_key": "Figure10", "fig_uri": "8-Figure10-1.png", "text": "Figure 10 18F-FDG PET/CT\u2014FDG-avid, morphologically benign appearing lymph nodes. A 73-year-old woman presented with hematuria and was found to have invasive high-grade papillary urothelial carcinoma on cystoscopy. One year following cystectomy and local lymph node dissection, a PET-CT was performed and demonstrated foci of increased radiotracer uptake at multiple locations including the left periaortic (A, black arrow) and left common iliac (C) stations, corresponding to morphologically normal lymph nodes on the associated non-contrast CT (B,D; white arrows). 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{"pdf_hash": "3a966a999fca5b6b75960650cc52ae854870d084", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Examples of current usages of cardiac MRI for tissue characterization in children [7]. A. Mid-ventricular short-axis T1 mapping of a 7-year-old boy with Duchenne myopathy. In the inferior and inferolateral segments, higher T1 values before injection and lower T1 values after injection reveal the presence of diffuse fibrosis. B. Late gadolinium enhancement image of the same heart. The presence of fibrosis is shown by the red contouring. C. Post-gadolinium four-chamber SSFP view (T1/T2-weighed image) very clearly revealing the extension of fibrosis in the lateral wall of the same heart (red outline). 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{"pdf_hash": "09bc97c3dca3a8937522e02b312a5b6ee5365f2b", "fig_key": "Figure1", "fig_uri": "7-Figure1-1.png", "text": "Fig. 1 Morphology and composition of renal tubular crystal deposits in stone formers (SFs) and non-stone formers (NSFs). a Crystal attachment to the tubular walls detected by polarized light optical microphotography of hematoxylin and eosin-stained renal cortex sections (magnification, \u00d7 800). b Crystal attachment to the tubular walls detected by scanning electron microscopy (SEM) of the crystal ultrastructure. c Energy-dispersive X-ray spectroscopy (EDX) of the mineral components on the surface of SEM-detected crystal deposits. 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{"pdf_hash": "53a62f8a929dce5d03e38746c9ce46fa50080b0c", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4. (a) Bedside chest radiograph showing the inadequate positioning of the hemodialysis catheter in the ipsilateral right internal jugular vein after catheter insertion in the right subclavian vein (black arrow). (b) Ultrasound subxiphoid view showing right atrium (RA) and ventricle (RV) before the administration of microbubbles through the distal lumen of the catheter. (c) Ultrasound subxiphoid view showing the absence of microbubbles in RA and RV 4 seconds after their flush through the distal lumen of the catheter. 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{"pdf_hash": "b821ea30e7157d5a851894219a7e202024cac61b", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Figure 1. Naked mole-rat. Representative photomicrographs of Nissl-stained coronal hemisections (A,F) and the corresponding film autoradiographs (B,G, left/right reversed to facilitate comparisons) showing CRF1 binding (B) and CRF2 binding (G) at the rostrocaudal midrostrocaudal level of the rostral nucleus accumbens in a male naked mole-rat. Representative darkfield and brightfield photomicrographs showing CRF-ir processes (C,D1/2,E1/2) and Ucn 3-ir processes (H,I1/2) at the rostrocaudal level of the rostral nucleus accumbens in a male naked mole-rat. Boxed regions containing CRF-ir processes (D1,E1) or Ucn 3-ir processes (I1) are shown at higher magnification (D2,E2,I2, each of which contains a further magnification from a smaller to a larger boxed region). Cg, cingulate cortex; NAc, nucleus accumbens; PC, piriform cortex; TT, taenia tecta. 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{"pdf_hash": "212a56a82ee7c014b5b2d41a171793a9f7193335", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. Ultrasonography (US) findings of cardiac rhbdomyomas in a 34-week fetus with tuberous sclerosis. A. Four chamber view of fetal heart shows echogenic masses at the interventricular sepum (arrow) and in the left and right ventricles (arrowheads). B. 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{"pdf_hash": "a39b8cdd74efd9b1d0d205756653ce8f788be6fb", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4. Nuclear capsids localize to enlarged nuclear corrals. PtK2 cells were left noninfected (noninf) or infected with mEGFP-VP26 tagged PRV at an MOI of 100 (inf). At 4 h postinfection, cells were fixed and stained with 0.5 \u03bcg/mL Hoechst 33342 Abs imaged with spinning-disk microscopy. After infection, chromatin structure becomes more porous and capsids can be found in large and small (white arrow) corrals. 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{"pdf_hash": "1be3ce22b7d72174cba532ab162a11f92dd66e14", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Imaging studies of the lung nodule at the time of hospitalisation (a, b) and 6 months after disease onset (c, d). a. Computed tomography (CT) at the time of hospitalisation. The white arrow indicates a nodule with a cavity in the upper lobe of the left lung. b. Gallium scintigraphy (67Ga-citrate) at the time of hospitalisation. The white arrow indicates high accumulation of gallium at the same location as the lung lesion. c. CT 6 months after disease onset. The lung lesion has disappeared, and a small scar remains. d. Somatostatin scintigraphy (111In-Pentetreotide) 6 months after disease onset. There is no accumulation in the left upper lobe (white arrow). 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{"pdf_hash": "81c0206a9d333959f4625c0f6af00cd06883e183", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Postoperative magnetic resonance imaging (MRI). No residul tumor is found on the (A) saggital postcontrast T1-weighted, as well as the coronal (B) postcontrast T1-weighted and (C) T2-weighted MRI.", "width": 1404, "height": 534, "subcaptions": {"a": [40, 41, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [32, 33, 34, 40, 41, 11, 12, 13, 14, 15, 16, 17, 29, 30, 31], "c": [36, 37, 38, 39, 40, 41, 11, 12, 13, 14, 15, 16, 17]}, "subfigures": [{"id": "98fd8e20-d37d-4706-8e9e-b2f95e556193", "label": "a", "points": [[37.8, 24], [37.8, 500.9], [468.1, 500.9], [468.1, 24]], "color": "yellow"}, {"id": "5d7f049d-a697-4159-b5c9-fc9c0be4c273", "label": "b", "points": [[490.2, 19.6], [490.2, 503.1], [907.2, 503.1], [907.2, 19.6]], "color": "cyan"}, {"id": "3df1feff-d952-4b15-9f5f-a81d957be792", "label": "c", "points": [[936, 26.3], [936, 503.1], [1368.5, 503.1], [1368.5, 26.3]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Postoperative", "start": 10, "end": 23, "id": 3}, {"text": "magnetic", "start": 24, "end": 32, "id": 4}, {"text": "resonance", "start": 33, "end": 42, "id": 5}, {"text": "imaging", "start": 43, "end": 50, "id": 6}, {"text": "(", "start": 51, "end": 52, "id": 7}, {"text": "MRI", "start": 52, "end": 55, "id": 8}, {"text": ")", "start": 55, "end": 56, "id": 9}, {"text": ".", "start": 56, "end": 57, "id": 10}, {"text": "No", "start": 58, "end": 60, "id": 11}, {"text": "residul", "start": 61, "end": 68, "id": 12}, {"text": "tumor", "start": 69, "end": 74, "id": 13}, {"text": "is", "start": 75, "end": 77, "id": 14}, {"text": "found", "start": 78, "end": 83, "id": 15}, {"text": "on", "start": 84, "end": 86, "id": 16}, {"text": "the", "start": 87, "end": 90, "id": 17}, {"text": "(", "start": 91, "end": 92, "id": 18}, {"text": "A", "start": 92, "end": 93, "id": 19}, {"text": ")", "start": 93, "end": 94, "id": 20}, {"text": "saggital", "start": 95, "end": 103, "id": 21}, {"text": "postcontrast", "start": 104, "end": 116, "id": 22}, {"text": "T1-weighted", "start": 117, "end": 128, "id": 23}, {"text": ",", "start": 128, "end": 129, "id": 24}, {"text": "as", "start": 130, "end": 132, "id": 25}, {"text": "well", "start": 133, "end": 137, "id": 26}, {"text": "as", "start": 138, "end": 140, "id": 27}, {"text": "the", "start": 141, "end": 144, "id": 28}, {"text": "coronal", "start": 145, "end": 152, "id": 29}, {"text": "(", "start": 153, "end": 154, "id": 30}, {"text": "B", "start": 154, "end": 155, "id": 31}, {"text": ")", "start": 155, "end": 156, "id": 32}, {"text": "postcontrast", "start": 157, "end": 169, "id": 33}, {"text": "T1-weighted", "start": 170, "end": 181, "id": 34}, {"text": "and", "start": 182, "end": 185, "id": 35}, {"text": "(", "start": 186, "end": 187, "id": 36}, {"text": "C", "start": 187, "end": 188, "id": 37}, {"text": ")", "start": 188, "end": 189, "id": 38}, {"text": "T2-weighted", "start": 190, "end": 201, "id": 39}, {"text": "MRI", "start": 202, "end": 205, "id": 40}, {"text": ".", "start": 205, "end": 206, "id": 41}]}
{"pdf_hash": "8c38ff175f66d9634b6b8fb40ea333720954a741", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. (A) Magnetic resonance imaging was performed. The red arrow indicates the absence of uterine myometrium between the bladder and placenta. The white arrow indicates the placenta invades into the uterine myometrium but not deep enough to invade into the bladder muscle. (B) A laparotomy revealed multiple large blood vessels and the placenta present throughout the anterior uterine wall in the lower uterine segment. From the operative findings, we suspected placenta percreta. (C) A transverse uterine fundal incision was performed. We were careful to avoid rupturing the fetal membrane. Minimal bleeding was observed from the incision site.", "width": 1378, "height": 350, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "b": [50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84], "c": [85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114]}, "subfigures": [{"id": "d95e28d1-abbe-4b2b-8ba5-74d7e61edc42", "label": "a", "points": [[2.2, 0], [2.2, 320], [444.1, 320], [444.1, 0]], "color": "yellow"}, {"id": "03614ca4-6fc5-4e08-8271-03bdcf72c783", "label": "b", "points": [[455, 320], [455, 0], [916.6, 0], [916.6, 320]], "color": "cyan"}, {"id": "d2103fb2-c1c8-4bc3-8d73-7ff4cd93900a", "label": "c", "points": [[929.6, 0], [929.6, 311.3], [1375.9, 311.3], [1375.9, 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{"pdf_hash": "2b3bb0091a40331d9715b19bdcaf1f71249eca61", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig. 5 Early diagnosed group. a X-ray shows a fracture of the waist of the diagnosis. Thumb spica cast installed. b Three months after cast immobiliza treatment initiated. c After a month of LIPUS treatment, complete healing", "width": 1014, "height": 384, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "324fc307-d772-433b-9c5b-91e281372109", "label": "a", "points": [[35.7, 17.4], [35.7, 363.4], [383.3, 363.4], [383.3, 17.4]], "color": "yellow"}, {"id": "4d9247ed-3885-4a1e-8b9a-dc08e49e9c71", "label": "b", "points": [[431.4, 17.4], [431.4, 363.4], [689.3, 363.4], [689.3, 17.4]], "color": "cyan"}, {"id": "380d4b8e-6aac-4cc3-b1b9-1a5836324b5c", "label": "c", "points": [[722.9, 20.6], [722.9, 353.8], [984, 353.8], [984, 20.6]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": "Early", "start": 7, "end": 12, "id": 3}, {"text": "diagnosed", "start": 13, "end": 22, "id": 4}, {"text": "group", "start": 23, "end": 28, "id": 5}, {"text": ".", "start": 28, "end": 29, "id": 6}, {"text": "a", "start": 30, "end": 31, "id": 7}, {"text": "X", "start": 32, "end": 33, "id": 8}, {"text": "-", "start": 33, "end": 34, "id": 9}, {"text": "ray", "start": 34, "end": 37, "id": 10}, {"text": "shows", "start": 38, "end": 43, "id": 11}, {"text": "a", "start": 44, "end": 45, "id": 12}, {"text": "fracture", "start": 46, "end": 54, "id": 13}, {"text": "of", "start": 55, "end": 57, "id": 14}, {"text": "the", "start": 58, "end": 61, "id": 15}, {"text": "waist", "start": 62, "end": 67, "id": 16}, {"text": "of", "start": 68, "end": 70, "id": 17}, {"text": "the", "start": 71, "end": 74, "id": 18}, {"text": "diagnosis", "start": 75, "end": 84, "id": 19}, {"text": ".", "start": 84, "end": 85, "id": 20}, {"text": "Thumb", "start": 86, "end": 91, "id": 21}, {"text": "spica", "start": 92, "end": 97, "id": 22}, {"text": "cast", "start": 98, "end": 102, "id": 23}, {"text": "installed", "start": 103, "end": 112, "id": 24}, {"text": ".", "start": 112, "end": 113, "id": 25}, {"text": "b", "start": 114, "end": 115, "id": 26}, {"text": "Three", "start": 116, "end": 121, "id": 27}, {"text": "months", "start": 122, "end": 128, "id": 28}, {"text": "after", "start": 129, "end": 134, "id": 29}, {"text": "cast", "start": 135, "end": 139, "id": 30}, {"text": "immobiliza", "start": 140, "end": 150, "id": 31}, {"text": "treatment", "start": 151, "end": 160, "id": 32}, {"text": "initiated", "start": 161, "end": 170, "id": 33}, {"text": ".", "start": 170, "end": 171, "id": 34}, {"text": "c", "start": 172, "end": 173, "id": 35}, {"text": "After", "start": 174, "end": 179, "id": 36}, {"text": "a", "start": 180, "end": 181, "id": 37}, {"text": "month", "start": 182, "end": 187, "id": 38}, {"text": "of", "start": 188, "end": 190, "id": 39}, {"text": "LIPUS", "start": 191, "end": 196, "id": 40}, {"text": "treatment", "start": 197, "end": 206, "id": 41}, {"text": ",", "start": 206, "end": 207, "id": 42}, {"text": "complete", "start": 208, "end": 216, "id": 43}, {"text": "healing", "start": 217, "end": 224, "id": 44}]}
{"pdf_hash": "0ea6d4daf66af0712819e19b77cd5dba9c358d9f", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 The clinicopathological findings of Case 2. a The preoperative findings: Abdominal CT showed an enlarged left adrenal gland (black arrow). b The macroscopic appearance: The cross-section of the adrenal tumor was solid and grayish white. c, d The histopathological findings: The histopathological examination of the adrenal tumor showed adenocarcinoma, which was compatible with metastasis of primary colon cancer", "width": 1014, "height": 684, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "c": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72]}, "subfigures": [{"id": "b26eb982-de3f-43de-b7ff-f10fc627cf18", "label": "a", "points": [[39.3, 15.1], [39.3, 337.1], [503.8, 337.1], [503.8, 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{"pdf_hash": "d6121ed4d25c2ac4a87ffcd6ae4604325c977fe8", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Reconstructed midsagittal postmortem computed tomography images of finless porpoise diagnosed with atlanto-occipital dissociation (AOD) in dorsal-ventral dimension, (a) dorsally displaced AOD and (b) ventrally displaced AOD.", "width": 534, "height": 710, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 40], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 34, 35, 36, 37, 38, 39, 40]}, "subfigures": [{"id": "27b8add3-3d12-4774-bf40-a8b39523e54d", "label": "a", "points": [[5, 0.8], [5, 351.8], [530, 351.8], [530, 0.8]], "color": "yellow"}, {"id": "9c8f9805-80e6-44c2-b267-789c945f3f7c", "label": "b", "points": [[5, 359.8], [5, 706.8], [528, 706.8], [528, 359.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Reconstructed", "start": 10, "end": 23, "id": 3}, {"text": "midsagittal", "start": 24, "end": 35, "id": 4}, {"text": "postmortem", "start": 36, "end": 46, "id": 5}, {"text": "computed", "start": 47, "end": 55, "id": 6}, {"text": "tomography", "start": 56, "end": 66, "id": 7}, {"text": "images", "start": 67, "end": 73, "id": 8}, {"text": "of", "start": 74, "end": 76, "id": 9}, {"text": "finless", "start": 77, "end": 84, "id": 10}, {"text": "porpoise", "start": 85, "end": 93, "id": 11}, {"text": "diagnosed", "start": 94, "end": 103, "id": 12}, {"text": "with", "start": 104, "end": 108, "id": 13}, {"text": "atlanto", "start": 109, "end": 116, "id": 14}, {"text": "-", "start": 116, "end": 117, "id": 15}, {"text": "occipital", "start": 117, "end": 126, "id": 16}, {"text": "dissociation", "start": 127, "end": 139, "id": 17}, {"text": "(", "start": 140, "end": 141, "id": 18}, {"text": "AOD", "start": 141, "end": 144, "id": 19}, {"text": ")", "start": 144, "end": 145, "id": 20}, {"text": "in", "start": 146, "end": 148, "id": 21}, {"text": "dorsal", "start": 149, "end": 155, "id": 22}, {"text": "-", "start": 155, "end": 156, "id": 23}, {"text": "ventral", "start": 156, "end": 163, "id": 24}, {"text": "dimension", "start": 164, "end": 173, "id": 25}, {"text": ",", "start": 173, "end": 174, "id": 26}, {"text": "(", "start": 175, "end": 176, "id": 27}, {"text": "a", "start": 176, "end": 177, "id": 28}, {"text": ")", "start": 177, "end": 178, "id": 29}, {"text": "dorsally", "start": 179, "end": 187, "id": 30}, {"text": "displaced", "start": 188, "end": 197, "id": 31}, {"text": "AOD", "start": 198, "end": 201, "id": 32}, {"text": "and", "start": 202, "end": 205, "id": 33}, {"text": "(", "start": 206, "end": 207, "id": 34}, {"text": "b", "start": 207, "end": 208, "id": 35}, {"text": ")", "start": 208, "end": 209, "id": 36}, {"text": "ventrally", "start": 210, "end": 219, "id": 37}, {"text": "displaced", "start": 220, "end": 229, "id": 38}, {"text": "AOD", "start": 230, "end": 233, "id": 39}, {"text": ".", "start": 233, "end": 234, "id": 40}]}
{"pdf_hash": "874779283391886b33e52ac183ffb56f189511cd", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Panel A. 2D Echocardiogram. Parasternal long axis view showing aneurysmal left venticular outflow tract (arrows). Panel B. TEE showing gross displacement of bioprosthetic aortic valve (asterisk) with aneurysmal dilatation pressing into the left atrium (arrow: mitral valve). Panel C. Aneurysm expanded with left ventricular contraction; aortic valve (asterisk). 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{"pdf_hash": "08f0b9ba303d0f34347178201fe7cece9b3533ab", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "FIG. 6. Excitation profiles and TSE images obtained without (left columns) and with (right columns) the use of 3 kT-points on the PTx system. Raw TSE images are presented in the second and third rows. Solid boxes: Zooms over the top-right area of the axial profiles presented in the second row. Improved GM-WM contrast is clearly observed in the temporal lobe in the inset corresponding to the anatomical image acquired by using 3 kT-points. Dashed boxes: Sagittal and coronal views of the raw TSE images for slices different from the ones presented in the second row. Blue arrows highlight brain parts for which signal homogeneity was highly improved, whereas green arrows point out the fact that structures known to be iron rich are clearly distinguishable on the TSE images acquired using kT-points. 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{"pdf_hash": "7591aa9c76b8e0f99f1b57c6b9bdf11c2a3c5cca", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Case 17: An 18-year-old female had a right parietal glioblastoma partially removed in a hospital in May 2005 (A). We performed re-craniotomy to remove the additional tumor and settled the Ommaya\u2019s reservoir to fill the cavity with air before neutron irradiation (B). MRI taken 26 months after BNCT is shown in C. The white arrow shows a newly appearing Gd-enhanced lesion, which was judged to be radiation necrosis. 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{"pdf_hash": "44994b477c3299657ac5f69b57cece360242d36b", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2 In situ hybridisation detection of K light chain mRNA and IgA by immunofluorescence. (2A) Kappa light chain mRNA (red) and immunofluorescence for cytoplasmic IgA (green). Double labelled cells are seen with red nuclear andgreen cytoplasmic signal, (viewed before counterstaining). (2B) Bright field counterpart of (2A). 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{"pdf_hash": "5c70db84356e37cf7bcf3a3eabded90b3656365d", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Fig. 6. Colocalisation studies of Tat-TPP versus LysoTracker Green or MitoTracker Green in HN5 cells by confocal microscopy. Cells were incubated 2.5 \u03bcM Tat-TPP for 18 h. 50 nM of LysoTracker Green or MitoTracker Green was applied to cells 30 min before imaging. A and D: Tat-TPP; B: LysoTracker Green; C: merged A and B; E: MitoTracker Green; F: merged D and E. 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{"pdf_hash": "40345a3f284846279918160165b438b66823ff8a", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Molar enamel organs from K14-Cre p120-cKO mice are dysplastic and are adjacent to blood filled sinusoids. Wild-type mouse molars with identified tissue structures are presented (A) as a comparison to the molars from the cKO mice (B\u2013D). Note that the enamel space (resulting from the demineralization of enamel) in the cKO mouse molars was greatly reduced in width (B) when compared to wild-type molars. Unusual large, blood-filled sinusoids were present, such as the one between the first (M1) and second (M2) molars in this section. The enamel organ morphology became dysplastic in the p120 ablated mice (C) and a high magnification (D) of an enamel organ between two cusp tips (CT) revealed the presence of clear vacuoles (Vac) where tissues were separated. With few exceptions, the ameloblasts, stratum intermedium, and stellate reticulum layers could not be definitively identified. A thick normal appearing layer of dentin was present in the cKO mouse molar teeth. 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{"pdf_hash": "576b8edfcf328f7c382399ad627d1f1491a68a47", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 DEDD requires a nuclear localization to be proapoptotic. (A) Localization of FLAG tagged DEDD NLS mutants in transiently transfected 293T cells. Arrows point to subnuclear structures that are enriched in transfected DEDD. (B) The degree of DNA fragmentation in 293T cells transiently transfected with DEDD or DEDD without a functional NLS (DNLS1-3). The experiment shown is representative of three independent experiments. 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{"pdf_hash": "5d3b970e94390bff19e07fa68a91fd0e96e46078", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Computed tomography of the abdomen and pelvis showing a large-sized mesenteric cyst. A: Coronal plane-craniocadual diameter of 21.7 cm; B: Transverse plane - transverse diameter of 11.8 cm; C: Sagittal plane - antero-posterior diameter of 14 cm.", "width": 1076, "height": 396, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "c": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "57879e78-f766-4aa1-8741-b5a188ea5a15", "label": "a", "points": [[0.9, 6.5], [0.9, 390.7], [344.3, 390.7], [344.3, 6.5]], "color": "yellow"}, {"id": "3b83e363-7d8f-4e45-946c-61450fc32af3", "label": "b", "points": [[357.9, 1.4], [357.9, 394.1], [794.7, 394.1], [794.7, 1.4]], "color": "cyan"}, {"id": "e1f885e9-62e4-46ae-b25f-5638fb0dc486", "label": "c", "points": [[815.1, 6.5], [815.1, 392.4], [1073.5, 392.4], [1073.5, 6.5]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Computed", "start": 9, "end": 17, "id": 2}, {"text": "tomography", "start": 18, "end": 28, "id": 3}, {"text": "of", "start": 29, "end": 31, "id": 4}, {"text": "the", "start": 32, "end": 35, "id": 5}, {"text": "abdomen", "start": 36, "end": 43, "id": 6}, {"text": "and", "start": 44, "end": 47, "id": 7}, {"text": "pelvis", "start": 48, "end": 54, "id": 8}, {"text": "showing", "start": 55, "end": 62, "id": 9}, {"text": "a", "start": 63, "end": 64, "id": 10}, {"text": "large", "start": 65, "end": 70, "id": 11}, {"text": "-", "start": 70, "end": 71, "id": 12}, {"text": "sized", "start": 71, "end": 76, "id": 13}, {"text": "mesenteric", "start": 77, "end": 87, "id": 14}, {"text": "cyst", "start": 88, "end": 92, "id": 15}, {"text": ".", "start": 92, "end": 93, "id": 16}, {"text": "A", "start": 94, "end": 95, "id": 17}, {"text": ":", "start": 95, "end": 96, "id": 18}, {"text": "Coronal", "start": 97, "end": 104, "id": 19}, {"text": "plane", "start": 105, "end": 110, "id": 20}, {"text": "-", "start": 110, "end": 111, "id": 21}, {"text": "craniocadual", "start": 111, "end": 123, "id": 22}, {"text": "diameter", "start": 124, "end": 132, "id": 23}, {"text": "of", "start": 133, "end": 135, "id": 24}, {"text": "21.7", "start": 136, "end": 140, "id": 25}, {"text": "cm", "start": 141, "end": 143, "id": 26}, {"text": ";", "start": 143, "end": 144, "id": 27}, {"text": "B", "start": 145, "end": 146, "id": 28}, {"text": ":", "start": 146, "end": 147, "id": 29}, {"text": "Transverse", "start": 148, "end": 158, "id": 30}, {"text": "plane", "start": 159, "end": 164, "id": 31}, {"text": "-", "start": 165, "end": 166, "id": 32}, {"text": "transverse", "start": 167, "end": 177, "id": 33}, {"text": "diameter", "start": 178, "end": 186, "id": 34}, {"text": "of", "start": 187, "end": 189, "id": 35}, {"text": "11.8", "start": 190, "end": 194, "id": 36}, {"text": "cm", "start": 195, "end": 197, "id": 37}, {"text": ";", "start": 197, "end": 198, "id": 38}, {"text": "C", "start": 199, "end": 200, "id": 39}, {"text": ":", "start": 200, "end": 201, "id": 40}, {"text": "Sagittal", "start": 202, "end": 210, "id": 41}, {"text": "plane", "start": 211, "end": 216, "id": 42}, {"text": "-", "start": 217, "end": 218, "id": 43}, {"text": "antero", "start": 219, "end": 225, "id": 44}, {"text": "-", "start": 225, "end": 226, "id": 45}, {"text": "posterior", "start": 226, "end": 235, "id": 46}, {"text": "diameter", "start": 236, "end": 244, "id": 47}, {"text": "of", "start": 245, "end": 247, "id": 48}, {"text": "14", "start": 248, "end": 250, "id": 49}, {"text": "cm", "start": 251, "end": 253, "id": 50}, {"text": ".", "start": 253, "end": 254, "id": 51}]}
{"pdf_hash": "958a52f23c3375f417332fccf0c9b94bbe2fd1d8", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Magnetic resonance images (MRI) of the head prior to initiation of anti-Toxoplasma therapy. The axial T1- and T2-weighted MRI images show high intensity in the marginal lesions and low intensity in the lesions in the cerebrum. 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{"pdf_hash": "bb4eeb3f7abe27080460c6e0107caa5c2427a488", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Magnetic resonance imaging (MRI) scan of the brain. (A) Postcontrast T1WI image showed a lesion in the right frontal lobe with ring-like enhancement (empty arrow). (B) T2 FLAIR showed a lesion with isointensity or slightly high signal intensity in the right frontal lobe with surrounding edema (empty arrow). (C) Postcontrast T1WI image showed the lesion in the right parietal lobe was strongly enhanced (white arrow). 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{"pdf_hash": "7f81354f0737a8a2b370e8a0b5dea68b3d704870", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 \u2013 (Case 1) (A) Positron emission tomography (PET)\u2013computed tomography (CT) (PET\u2013CT) shows avid uptake in the left breast mass with standardized uptake value (SUV) of 38.3. (B) Mild uptake seen in the left axillary nodes (yellow circle) with maximum SUV of 3.8. No evidence of metastatic disease was seen elsewhere on the PET. 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{"pdf_hash": "19cf2aae3ea17ebe18f40f4846670081217d4ea3", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 A 17-year-old patient, diagnosed with Ewing sarcoma in the distal third of the left tibia, which invaded the growth cartilage. A. Clinical aspects. B. Preoperative radiological examination. C. Whole body scintigraphy scan - replacement process space well vascularized to the left tibia D. MRI \u2013 fusiform heterogeneous tumor mass confined to tibia", "width": 644, "height": 1160, "subcaptions": {"a": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "b": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "1d4c4245-72dd-460b-a61f-8f35f1b595d8", "label": "a", "points": [[0.5, 3.9], [0.5, 467.8], [641.5, 467.8], [641.5, 3.9]], "color": "yellow"}, {"id": "62fbab30-1f23-4259-a392-e3b73d1c537b", "label": "b", "points": [[6.7, 505.9], [6.7, 1156], [635.4, 1156], [635.4, 505.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "17-year", "start": 9, "end": 16, "id": 4}, {"text": "-", "start": 16, "end": 17, "id": 5}, {"text": "old", "start": 17, "end": 20, "id": 6}, {"text": "patient", "start": 21, "end": 28, "id": 7}, {"text": ",", "start": 28, "end": 29, "id": 8}, {"text": "diagnosed", "start": 30, "end": 39, "id": 9}, {"text": "with", "start": 40, "end": 44, "id": 10}, {"text": "Ewing", "start": 45, "end": 50, "id": 11}, {"text": "sarcoma", "start": 51, "end": 58, "id": 12}, {"text": "in", "start": 59, "end": 61, "id": 13}, {"text": "the", "start": 62, "end": 65, "id": 14}, {"text": "distal", "start": 66, "end": 72, "id": 15}, {"text": "third", "start": 73, "end": 78, "id": 16}, {"text": "of", "start": 79, "end": 81, "id": 17}, {"text": "the", "start": 82, "end": 85, "id": 18}, {"text": "left", "start": 86, "end": 90, "id": 19}, {"text": "tibia", "start": 91, "end": 96, "id": 20}, {"text": ",", "start": 96, "end": 97, "id": 21}, {"text": "which", "start": 98, "end": 103, "id": 22}, {"text": "invaded", "start": 104, "end": 111, "id": 23}, {"text": "the", "start": 112, "end": 115, "id": 24}, {"text": "growth", "start": 116, "end": 122, "id": 25}, {"text": "cartilage", "start": 123, "end": 132, "id": 26}, {"text": ".", "start": 132, "end": 133, "id": 27}, {"text": "A.", "start": 134, "end": 136, "id": 28}, {"text": "Clinical", "start": 137, "end": 145, "id": 29}, {"text": "aspects", "start": 146, "end": 153, "id": 30}, {"text": ".", "start": 153, "end": 154, "id": 31}, {"text": "B.", "start": 155, "end": 157, "id": 32}, {"text": "Preoperative", "start": 158, "end": 170, "id": 33}, {"text": "radiological", "start": 171, "end": 183, "id": 34}, {"text": "examination", "start": 184, "end": 195, "id": 35}, {"text": ".", "start": 195, "end": 196, "id": 36}, {"text": "C.", "start": 197, "end": 199, "id": 37}, {"text": "Whole", "start": 200, "end": 205, "id": 38}, {"text": "body", "start": 206, "end": 210, "id": 39}, {"text": "scintigraphy", "start": 211, "end": 223, "id": 40}, {"text": "scan", "start": 224, "end": 228, "id": 41}, {"text": "-", "start": 229, "end": 230, "id": 42}, {"text": "replacement", "start": 231, "end": 242, "id": 43}, {"text": "process", "start": 243, "end": 250, "id": 44}, {"text": "space", "start": 251, "end": 256, "id": 45}, {"text": "well", "start": 257, "end": 261, "id": 46}, {"text": "vascularized", "start": 262, "end": 274, "id": 47}, {"text": "to", "start": 275, "end": 277, "id": 48}, {"text": "the", "start": 278, "end": 281, "id": 49}, {"text": "left", "start": 282, "end": 286, "id": 50}, {"text": "tibia", "start": 287, "end": 292, "id": 51}, {"text": "D.", "start": 293, "end": 295, "id": 52}, {"text": "MRI", "start": 296, "end": 299, "id": 53}, {"text": "\u2013", "start": 300, "end": 301, "id": 54}, {"text": "fusiform", "start": 302, "end": 310, "id": 55}, {"text": "heterogeneous", "start": 311, "end": 324, "id": 56}, {"text": "tumor", "start": 325, "end": 330, "id": 57}, {"text": "mass", "start": 331, "end": 335, "id": 58}, {"text": "confined", "start": 336, "end": 344, "id": 59}, {"text": "to", "start": 345, "end": 347, "id": 60}, {"text": "tibia", "start": 348, "end": 353, "id": 61}]}
{"pdf_hash": "820f0e9fb04cc7dcb5ca2c2bcd45481be7dbec08", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "FIGURE 3 | Intravital imaging of iNKT cells in the lymph node and spleen of Cxcr6 Gfp/+ mice. (A) Still image demonstrating distribution of iNKT cells (bright green) in different regions of a lymph node. Vasculature of the lymph node is labelled with PECAM-1 (blue). The medullar and interfollicular regions are outlined in yellow while the paracortex is outlined in white. 10\u00d7 objective, scale bar 210 \u00b5m. (B) Still snapshot of splenic iNKT cells (bright green) in red pulp of spleen reveals that these cells are located outside the vasculature (blue). 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{"pdf_hash": "0bcf7c2cd7d6f0188eddcbc53a98731a2497f3ce", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4 Patient 4. Sagittal T 1 -weighted image (A) showing the flat brainstem (white arrow). Axial T 2 -weighted image (B) showing supratentorial absence of myelination (white arrow) and dilatation of the lateral ventricles, particularly the posterior horns (black arrow). 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{"pdf_hash": "d75d39c91f56584ee5e2e212ccc505ec6075d4ce", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. Echocardiogram in patient 3 at the time of admission to neurology department due to stroke. Although dominant rhythm during the admission was atrial fibrillation, sinus rhythm was occasionally noted and even in the sinus rhythm, patient showed restrictive physiology. (A) Apical 4 chamber view showing marked left atrial enlargement. (B, C) Mitral inflow and mitral annulus velocity profiles. 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{"pdf_hash": "bdaad99d47f3f8bd02114e9252b98154a2ae065a", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Fig. 2 Double aortic arch. a Illustration showing the appearances of a double aortic arch, with a dominant right arch. The right arch gives off the right subclavian (RSC) and right common carotid (RCC) branches, while the left arch gives off the left subclavian (LSC) and left common carotid (LCC) arteries. Both the trachea and oesophagus are completely encircled and compressed by the vascular ring. b Axial CT scan shows the fourvessel sign. The first branch is the right subclavian (RSC) artery, the second is the right common carotid artery (RCC), the third is the left common carotid (LCC) artery and the fourth is the left subclavian (LSC) artery. c Axial MIP image shows bilateral aortic arches encircling the trachea and oesophagus. 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{"pdf_hash": "2f4e8a58131a6853f404a03463aad711c03b610f", "fig_key": "Figure5", "fig_uri": "12-Figure5-1.png", "text": "Figure 5. 64 Cu-fluorescent magnetic NPs facilitate PET-CT imaging of inflammatory atherosclerosis in apoE \u2212/\u2212 mice. Fused PET-CT images of the (A) aortic root, (B) arch, and (C) carotid artery of aged apoE \u2212/\u2212 mice show a strong PET signal in these vascular territories with high plaque burden, whereas no activity is observed in the same vasculature of wild-type mice (D)-(F). (G)-(H) Hematoxylin and eosin histology of respective vascular regions, which carry a high plaque burden in apoE \u2212/\u2212 but not in wild-type mice (I)-(K) (magnification: 400\u00d7 for (G) and (I), 200\u00d7 for (H) and (K); bar = 0.4 mm). The three-dimensional maximum intensity reconstruction of the fused data set (L) demonstrates the focal PET signal area surrounded by dashed white line in the proximal thoracic aorta area surrounded by solid white line of an apoE \u2212/\u2212 mouse but not in a wild-type mouse (M). 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{"pdf_hash": "49754cd774609b85eb766c33128fffed12da9916", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 (a) MRI of patient 2 in March 2005. (b) MRI of patient 2 in June 2007. MRI, magnetic resonance imaging.", "width": 936, "height": 592, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12], "b": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23]}, "subfigures": [{"id": "f52071a0-ab6b-4663-8bdd-6c8fb6e8c20b", "label": "a", "points": [[45.9, 1.2], [45.9, 557.2], [430.3, 557.2], [430.3, 1.2]], "color": "yellow"}, {"id": "4c0a46cf-9224-40a3-b3d9-57e5b3643822", "label": "b", "points": [[471.7, 1.2], [471.7, 561.6], [924.2, 561.6], [924.2, 1.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "MRI", "start": 13, "end": 16, "id": 5}, {"text": "of", "start": 17, "end": 19, "id": 6}, {"text": "patient", "start": 20, "end": 27, "id": 7}, {"text": "2", "start": 28, "end": 29, "id": 8}, {"text": "in", "start": 30, "end": 32, "id": 9}, {"text": "March", "start": 33, "end": 38, "id": 10}, {"text": "2005", "start": 39, "end": 43, "id": 11}, {"text": ".", "start": 43, "end": 44, "id": 12}, {"text": "(", "start": 45, "end": 46, "id": 13}, {"text": "b", "start": 46, "end": 47, "id": 14}, {"text": ")", "start": 47, "end": 48, "id": 15}, {"text": "MRI", "start": 49, "end": 52, "id": 16}, {"text": "of", "start": 53, "end": 55, "id": 17}, {"text": "patient", "start": 56, "end": 63, "id": 18}, {"text": "2", "start": 64, "end": 65, "id": 19}, {"text": "in", "start": 66, "end": 68, "id": 20}, {"text": "June", "start": 69, "end": 73, "id": 21}, {"text": "2007", "start": 74, "end": 78, "id": 22}, {"text": ".", "start": 78, "end": 79, "id": 23}, {"text": "MRI", "start": 80, "end": 83, "id": 24}, {"text": ",", "start": 83, "end": 84, "id": 25}, {"text": "magnetic", "start": 85, "end": 93, "id": 26}, {"text": "resonance", "start": 94, "end": 103, "id": 27}, {"text": "imaging", "start": 104, "end": 111, "id": 28}, {"text": ".", "start": 111, "end": 112, "id": 29}]}
{"pdf_hash": "ca460bfba7e77c3a270492e2d76e089fcf660824", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: Magnetic resonance imaging scans of the left elbow of an eight year-old boy from the axial view showing an ill-defined and multilobulated lesion, including (A) T1-weighted, (B) T2-weighted, (C) T1-weighted fat-saturated and (D) T1-weighted postgadolinium contrast images. The epicentre of the mass was located in the proximal intramedullary region involving the supinator muscle in the posteromedial compartment of the left proximal forearm. The lesion was slightly hyperintense on T1-weighted imaging and hyperintense on T2-weighted imaging, with internal linear and punctate hypodensities. The signal intensity was not suppressed on fat saturation. Post-gadolinium administration, the lesion demonstrated avid yet heterogeneous enhancement (arrow) with a well-defined oval calcification (arrowhead).", "width": 584, "height": 588, "subcaptions": {"a": [32, 33, 34, 35, 56, 57, 84, 85, 86, 87, 88, 89, 90, 91, 97, 98, 99, 100, 101, 102, 103, 104], "b": [37, 38, 39, 40, 56, 57, 84, 85, 86, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104], "c": [105, 42, 43, 44, 45, 46, 47, 48, 106, 107, 108, 109, 110, 111, 112, 56, 57, 113, 114], "d": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 50, 51, 52, 53, 54, 55, 56, 57, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "39997eb9-0a87-4f4d-b69a-bbd1fe00b167", "label": "a", "points": [[18.5, 17], [18.5, 287], [288.5, 287], [288.5, 17]], "color": "yellow"}, {"id": "8dcf25a4-54e3-46c7-b409-9e0c74b1f464", "label": "b", "points": [[295.5, 18], [295.5, 288], [563.5, 288], [563.5, 18]], "color": "cyan"}, {"id": 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{"pdf_hash": "b0a7d1278253d46081bbd36c1e09844de492a562", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. 64-year-old woman with pancreatic cancer. Patient had dysfunction of endoscopic metallic stent and subsequently inserted plastic stent. A. Cholangiogram shows multifocal filling defects in bile duct and dysfunction of endoscopic metallic and plastic stent. B. After removal of plastic stent, bile duct and metallic stent were irrigated through drainage catheter. C. Cholangiogram after placement of double stents (10 mm x 23 cm) shows fluent passage of contrast medium through stent into jejunum. Note inner covered stent (arrows) and outer uncovered stent (arrowheads).", "width": 1378, "height": 550, "subcaptions": {"a": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "c": [61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100]}, "subfigures": [{"id": "f36f64fc-e7ea-439e-ac76-544e05e7b9ed", "label": "a", "points": [[0, 4.4], [0, 470.2], [448.5, 470.2], [448.5, 4.4]], "color": "yellow"}, {"id": "c1bf4caf-3631-44d9-a505-5f5d1d9865ae", "label": "b", "points": [[455, 2.2], [455, 472.4], [918.7, 472.4], [918.7, 2.2]], "color": "cyan"}, {"id": "c7299132-1220-46bd-8f62-6964e67d9b2e", "label": "c", "points": [[925.2, 4.4], [925.2, 472.4], [1375.9, 472.4], [1375.9, 4.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, 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{"pdf_hash": "ef3d423e9d10e9e2f80f2a55ff334a505fbf8be8", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Fig. 4 Perineurioma of the right posteromedial thigh. a, b Axial T2 SPAIR and sagittal STIR images reveal a mass (arrows) with honeycomb pattern, classic for perineurioma. c DWI (b = 400 s/mm2) and d colored ADC maps reveal high ADC = 1.9\u2013 2.0 \u00d7 10-3 mm2/s, consistent with a benign lesion. Surgical histology revealed a myxoid perineurioma", "width": 1048, "height": 1442, "subcaptions": {"a": [32, 33, 10, 13, 14, 15, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 12, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69], "d": [45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "4e7fae82-d86c-4aa6-9217-12064aeb8340", "label": "a", "points": [[39, 34.5], [39, 552.7], [596.9, 552.7], [596.9, 34.5]], "color": "yellow"}, {"id": "99213554-a583-463c-8e0c-8a16f72c5641", "label": "b", "points": [[605.2, 34.5], [605.2, 559.3], [1038.9, 559.3], [1038.9, 34.5]], "color": "cyan"}, {"id": "9e4cbdb7-8593-4ca4-bdaa-b8189b251338", "label": "c", "points": [[34, 562.6], [34, 1435.1], [442.9, 1435.1], [442.9, 562.6]], "color": "magenta"}, {"id": 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{"pdf_hash": "e6552a10f22240a7e47ba734dd4ddf1df6af8038", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Case 2. (A) Computed tomography showing the lesion in the sacrum. (B) 99 mTc HYNIC TOC SPECT/CT scans showing uptake in the same area. (C) The back wall of the S1 vertebral body was deficient and the cement leaked into the canal. (D) Hematoxylin and eosin-stained histological sections from the biopsy specimen confirmed extraadrenal pheochromocytoma. 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{"pdf_hash": "84ba8221635b489d2448824164ee36e48c79997d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Morphological changes of cells mashed by an ultrasonic processor. (A) Normal chondrocytes and (B) cells mashed by an ultrasonic processor showed no structure (original magnification, x200).", "width": 516, "height": 872, "subcaptions": {"a": [13, 14, 15, 16, 17], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "2aff912f-6987-4256-bd15-a9c02f85803f", "label": "a", "points": [[61.7, 6.3], [61.7, 401.3], [496.7, 401.3], [496.7, 6.3]], "color": "yellow"}, {"id": "1d6f1fd5-ae3d-4518-be82-de6e1942ae7a", "label": "b", "points": [[64.7, 445.7], [64.7, 830.7], [496.7, 830.7], [496.7, 445.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Morphological", "start": 10, "end": 23, "id": 3}, {"text": "changes", "start": 24, "end": 31, "id": 4}, {"text": "of", "start": 32, "end": 34, "id": 5}, {"text": "cells", "start": 35, "end": 40, "id": 6}, {"text": "mashed", "start": 41, "end": 47, "id": 7}, {"text": "by", "start": 48, "end": 50, "id": 8}, {"text": "an", "start": 51, "end": 53, "id": 9}, {"text": "ultrasonic", "start": 54, "end": 64, "id": 10}, {"text": "processor", "start": 65, "end": 74, "id": 11}, {"text": ".", "start": 74, "end": 75, "id": 12}, {"text": "(", "start": 76, "end": 77, "id": 13}, {"text": "A", "start": 77, "end": 78, "id": 14}, {"text": ")", "start": 78, "end": 79, "id": 15}, {"text": "Normal", "start": 80, "end": 86, "id": 16}, {"text": "chondrocytes", "start": 87, "end": 99, "id": 17}, {"text": "and", "start": 100, "end": 103, "id": 18}, {"text": "(", "start": 104, "end": 105, "id": 19}, {"text": "B", "start": 105, "end": 106, "id": 20}, {"text": ")", "start": 106, "end": 107, "id": 21}, {"text": "cells", "start": 108, "end": 113, "id": 22}, {"text": "mashed", "start": 114, "end": 120, "id": 23}, {"text": "by", "start": 121, "end": 123, "id": 24}, {"text": "an", "start": 124, "end": 126, "id": 25}, {"text": "ultrasonic", "start": 127, "end": 137, "id": 26}, {"text": "processor", "start": 138, "end": 147, "id": 27}, {"text": "showed", "start": 148, "end": 154, "id": 28}, {"text": "no", "start": 155, "end": 157, "id": 29}, {"text": "structure", "start": 158, "end": 167, "id": 30}, {"text": "(", "start": 168, "end": 169, "id": 31}, {"text": "original", "start": 169, "end": 177, "id": 32}, {"text": "magnification", "start": 178, "end": 191, "id": 33}, {"text": ",", "start": 191, "end": 192, "id": 34}, {"text": "x200", "start": 193, "end": 197, "id": 35}, {"text": ")", "start": 197, "end": 198, "id": 36}, {"text": ".", "start": 198, "end": 199, "id": 37}]}
{"pdf_hash": "3919f0b38ca6a9db57e351e687950f212c5118ea", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Computed tomography(CT) scan head showing foreign body passing from frontal to occipital region with metallic artifacts;(A) Parenchymal window and (B) bone window.", "width": 1028, "height": 1030, "subcaptions": {"a": [20, 21, 22, 23], "b": [25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "861fcaf5-cfd6-498e-bbf9-25d0654f1b83", "label": "a", "points": [[4.9, 6.5], [4.9, 349.2], [1026.4, 349.2], [1026.4, 6.5]], "color": "yellow"}, {"id": "452bbb79-8922-48e9-b3bc-572d2362c19d", "label": "b", "points": [[6.5, 352.4], [6.5, 1028], [1024.8, 1028], [1024.8, 352.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Computed", "start": 8, "end": 16, "id": 4}, {"text": "tomography(CT", "start": 17, "end": 30, "id": 5}, {"text": ")", "start": 30, "end": 31, "id": 6}, {"text": "scan", "start": 32, "end": 36, "id": 7}, {"text": "head", "start": 37, "end": 41, "id": 8}, {"text": "showing", "start": 42, "end": 49, "id": 9}, {"text": "foreign", "start": 50, "end": 57, "id": 10}, {"text": "body", "start": 58, "end": 62, "id": 11}, {"text": "passing", "start": 63, "end": 70, "id": 12}, {"text": "from", "start": 71, "end": 75, "id": 13}, {"text": "frontal", "start": 76, "end": 83, "id": 14}, {"text": "to", "start": 84, "end": 86, "id": 15}, {"text": "occipital", "start": 87, "end": 96, "id": 16}, {"text": "region", "start": 97, "end": 103, "id": 17}, {"text": "with", "start": 104, "end": 108, "id": 18}, {"text": "metallic", "start": 109, "end": 117, "id": 19}, {"text": "artifacts;(A", "start": 118, "end": 130, "id": 20}, {"text": ")", "start": 130, "end": 131, "id": 21}, {"text": "Parenchymal", "start": 132, "end": 143, "id": 22}, {"text": "window", "start": 144, "end": 150, "id": 23}, {"text": "and", "start": 151, "end": 154, "id": 24}, {"text": "(", "start": 155, "end": 156, "id": 25}, {"text": "B", "start": 156, "end": 157, "id": 26}, {"text": ")", "start": 157, "end": 158, "id": 27}, {"text": "bone", "start": 159, "end": 163, "id": 28}, {"text": "window", "start": 164, "end": 170, "id": 29}, {"text": ".", "start": 170, "end": 171, "id": 30}]}
{"pdf_hash": "9e0545577185b6adef3f46def99500660ffc06f5", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. CTHA, CTAP, and DSA before and after the DEB-TACE procedure on first angiography. A: The tumors showed enhancement on CTHA. B: The tumors showed no enhancement on CTAP. C: DSA of the PHA demonstrated two hypervascular tumors. D: DSA after DEB-TACE showed tumor blush (arrowheads). CTHA: CT during hepatic arteriography, CTAP: CT during arterial portography, DSA: digital subtraction angiography, DEB-TACE: drug-eluting bead transarterial chemoembolization, PHA: proper hepatic artery, MHA: middle hepatic artery, RHA: right hepatic artery, LHA: left hepatic artery", "width": 960, "height": 896, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "c": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "d": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "82c2abef-9cb0-40ae-8178-7f462cd5e758", "label": "a", "points": [[6.3, 0.5], [6.3, 388.8], [471.9, 388.8], [471.9, 0.5]], "color": "yellow"}, {"id": "85beaca3-3deb-42e3-9f22-5480d57c3598", "label": "b", "points": [[485.6, 2], [485.6, 378.1], [942.1, 378.1], [942.1, 2]], "color": "cyan"}, {"id": "f6029edd-64bd-4dc1-bb4a-d43dd2d83e7a", "label": "c", "points": [[1.8, 391.8], [1.8, 861.9], [465.9, 861.9], [465.9, 391.8]], "color": "magenta"}, {"id": "be326407-6b30-46df-a468-9f33a434136b", "label": "d", "points": [[478, 391.8], [478, 861.9], [946.6, 861.9], [946.6, 391.8]], "color": "springgreen"}, {"id": "41fe8cbc-0364-4058-b532-59410b333e67", "label": "d", "points": [[892.3, 789.6], [892.3, 789.6], [899.9, 789.6], [899.9, 789.6]], "color": "tomato"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CTHA", "start": 10, "end": 14, "id": 3}, {"text": ",", "start": 14, "end": 15, "id": 4}, {"text": "CTAP", "start": 16, "end": 20, "id": 5}, {"text": ",", "start": 20, "end": 21, "id": 6}, {"text": "and", "start": 22, "end": 25, "id": 7}, {"text": "DSA", "start": 26, "end": 29, "id": 8}, {"text": "before", "start": 30, "end": 36, "id": 9}, {"text": "and", "start": 37, "end": 40, "id": 10}, {"text": "after", "start": 41, "end": 46, "id": 11}, {"text": "the", "start": 47, "end": 50, "id": 12}, {"text": "DEB", "start": 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{"pdf_hash": "84087ae7f8545ce58eb6ba51419db20ecaab0ae4", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Examples of lesions detected using 7-T T2*-weighted magnetic resonance imaging (MRI). A, one patient who received a diagnosis of multiple sclerosis (MS) had an MRI brain scan that shows a lesion that appears to have a vein coursing through it. B, another patient who did not receive a diagnosis of MS had an MRI brain scan that shows a microangiopathic lesion that does not have a vein passing through its center.", "width": 634, "height": 966, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "b": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84]}, "subfigures": [{"id": "3d9b6b01-b563-4778-8cf7-59b8f29f06c7", "label": "a", "points": [[3.5, 2], [3.5, 463.7], [628.5, 463.7], [628.5, 2]], "color": "yellow"}, {"id": "bd74d2db-8c0e-45f0-b7a7-f87719dc20e3", "label": "b", "points": [[4.5, 475.8], [4.5, 930.5], [629.5, 930.5], [629.5, 475.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Examples", "start": 10, 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{"pdf_hash": "9b62adba58680bc462725896b2ff3ae5705bc811", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Fig. 6 OFDI imaging of thrombus within a coronary stent implanted into a cadaveric coronary artery. The stent contains NIR fluorescent fibrin. A. OFDI Cross-sectional image with thrombus (yellow). B. OFDI cross sectional image with stent struts and micro-thrombi (yellow). C. NIRF cylindrical rendering of fibrin signal acquired by the dual-modality imaging catheter. D. Matching NIR FRI with Cy7 filter set confirms the in vivo findings. 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{"pdf_hash": "bc9726c35f317797001d0d1f559d5efbbe89383c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "FIG. 1. Results of DTA and reconstruction procedure on image of vertebral trabecular bone sample (3.2 \u00d7 3.2 \u00d7 2.1 mm 3 ). (A) An original CT image (full voxel model) of a trabecular bone sample. (B) Skeletonized image (skeleton model) of A. (C) Results of topological classification of B. Plate voxels are shown as dark gray, rod voxels in lighter shading. (D) Reconstructed structures with the trabecular type labeled for each voxel. (E) Rod-reconstructed model. 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{"pdf_hash": "9f6b37ee6504733e4dc4c52a12ff658d1a14335c", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Double-staining immunofluorescence of wt-MDCK cells: comparison between localization of reductase and mitochondria. Cells expressing wt-reductase were doubly stained with a goat polyclonal antibody against rat cyt b 5 reductase and a rabbit polyclonal antibody against bovine complex III. Reductase and complex III were revealed with biotinylated monoclonal anti-goat IgG, followed by Texas red-conjugated streptavidin (A) and FITC-conjugated donkey anti-rabbit IgG (B), respectively. The figure shows the same field of ceils viewed under the rhodamine (A) or FITC (B) filter. Reductase (A) shows a punctate pattern superimposed on a more diffuse reticular stain. The punctate pattern is in great part coincident with the pattern obtained with the anti-complex III antibody. Arrowheads in A and B indicate some of the points of coincidence. In addition, the anti-reductase antibody clearly stains the nuclear envelope (A, arrow), which is not stained by the anti-complex III antibody (B): Asterisks in both panels indicate cells that express low levels of reductase. 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{"pdf_hash": "0f96687ea13a57143a821b53417881e65fd7a292", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "Fig. 7 a\u2013g Ductal adenocarcinoma. Axial T2-weighted (a, b) and axial post-contrast T1-weighted images (c, d) show a small lesion at the level of the pancreatic body with an abrupt cut-off of the main pancreatic duct, better visualised on MRCP (e). After secretin stimulation (f, g) there is a persistent stenosis, without the duct-penetrating sign", "width": 1370, "height": 1174, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "e": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "f": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "6cce1a2b-d365-41cc-bec5-9a964dc4367e", "label": "a", "points": [[217.5, 6.7], [217.5, 355.1], [680.7, 355.1], [680.7, 6.7]], "color": "yellow"}, {"id": "2b82fa5f-a61a-4895-ac04-1a6d98c6ea64", "label": "a", "points": [[691.5, 6.7], [691.5, 368.1], [1128.7, 368.1], [1128.7, 6.7]], "color": "cyan"}, {"id": "2d614e7a-c447-4366-a109-b93018280962", 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{"pdf_hash": "e4c71fd906a172018848a05f486d5c4ef4a61170", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4 A 49-year-old woman with a known left adrenal adenoma, who developed right breast carcinoma that subsequently, metastasized to the left adrenal gland, resulting in the development of an ACT. Axial T1-weighted in-phase (A) and opposed-phase (B) magnetic resonance (MR) images show a nodule in the left adrenal gland, which is isointense on in-phase image and demonstrates signal drop on opposed-phase image (black arrow), consistent with an adrenal adenoma. (C) Axial contrast-enhanced CT image after 5 years demonstrates interval enlargement and heterogeneous enhancement of the left adrenal mass (white arrow), concerning for metastases from patient s known breast carcinoma. This lesion was proved to be an ACT on histopathologic examination. (D) Axial T1-weighted opposed-phase MR image depicts heterogeneous left adrenal mass with foci of mixed high and low signal intensity, consistent with ACT (black arrowhead), which was proved subsequently on histopathologic examination.", "width": 1292, "height": 1002, "subcaptions": {"a": [37, 38, 39, 40, 41, 42, 43, 44, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94], "b": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94], "c": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "d": [145, 146, 147, 148, 149, 150, 151, 152, 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{"pdf_hash": "1c1fe070d3ad47218fcbab1313791c73a755d823", "fig_key": "Figure11", "fig_uri": "9-Figure11-1.png", "text": "Figure 11 CT (A) and 2D TTE (B) slices crossing the region of membranous septum (MS). The septal leaflet (SL) of tricuspid valve is inserted on the right side of MS dividing it into atrioventricular (AVMS) and interventricular components (IVMS). (C) 3D TOE image showing a long axis view perspective. The area in red box is magnified in (D) showing in en face view the MB from a ventricular perspective (arrow). 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{"pdf_hash": "d87bfab1b64aad7b687ea9ffc15bb8c044c05b75", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3 Patient 15. There is a large erosion of the dorsal navicular bone, seen on the coronal and sagittal CT images (panels (a) and (b), red arrows) but no corresponding green-coded (MSU) deposits in or around the erosion on the DECT images (panels (c-d))", "width": 1010, "height": 864, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 23, 24, 25, 26, 27, 28, 29, 37], "b": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 22, 23, 24, 25, 26, 31, 32, 33, 37], "c": [20, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 63, 64], "d": [22, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 62, 63, 64]}, "subfigures": [{"id": "f36203f3-e6bc-4105-99eb-4233fa44018d", "label": "a", "points": [[35.1, 19.1], [35.1, 408.5], [343.1, 408.5], [343.1, 19.1]], "color": "yellow"}, {"id": "ebfa06cf-1879-4091-bad3-949bd252e689", "label": "b", "points": [[362.2, 414.9], [362.2, 23.9], [978.1, 23.9], [978.1, 414.9]], "color": "cyan"}, {"id": "f8b2ff87-b1e9-45af-9af5-2f756ccef11e", "label": "c", "points": [[38.3, 435.6], [38.3, 831.3], [346.2, 831.3], [346.2, 435.6]], "color": "magenta"}, {"id": "157ad200-6782-4d06-9f28-2c278cdfb756", "label": "d", "points": [[365.4, 828.1], [365.4, 437.2], [978.1, 437.2], [978.1, 828.1]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Patient", "start": 7, "end": 14, "id": 3}, {"text": "15", "start": 15, "end": 17, "id": 4}, {"text": ".", "start": 17, "end": 18, "id": 5}, {"text": "There", "start": 19, "end": 24, "id": 6}, {"text": "is", "start": 25, "end": 27, "id": 7}, {"text": "a", "start": 28, "end": 29, "id": 8}, {"text": "large", "start": 30, "end": 35, "id": 9}, {"text": "erosion", "start": 36, "end": 43, "id": 10}, {"text": "of", "start": 44, "end": 46, "id": 11}, {"text": "the", "start": 47, "end": 50, "id": 12}, {"text": "dorsal", "start": 51, "end": 57, "id": 13}, {"text": "navicular", "start": 58, "end": 67, "id": 14}, {"text": "bone", "start": 68, "end": 72, "id": 15}, {"text": ",", "start": 72, "end": 73, "id": 16}, {"text": "seen", "start": 74, "end": 78, "id": 17}, {"text": "on", "start": 79, "end": 81, "id": 18}, {"text": "the", "start": 82, "end": 85, "id": 19}, {"text": "coronal", "start": 86, "end": 93, "id": 20}, {"text": "and", "start": 94, "end": 97, "id": 21}, {"text": "sagittal", "start": 98, "end": 106, "id": 22}, {"text": "CT", "start": 107, "end": 109, "id": 23}, {"text": "images", "start": 110, "end": 116, "id": 24}, {"text": "(", "start": 117, "end": 118, "id": 25}, {"text": "panels", "start": 118, "end": 124, "id": 26}, {"text": "(", "start": 125, "end": 126, "id": 27}, {"text": "a", "start": 126, "end": 127, "id": 28}, {"text": ")", "start": 127, "end": 128, "id": 29}, {"text": "and", "start": 129, "end": 132, "id": 30}, {"text": "(", "start": 133, "end": 134, "id": 31}, {"text": "b", "start": 134, "end": 135, "id": 32}, {"text": ")", "start": 135, "end": 136, "id": 33}, {"text": ",", "start": 136, "end": 137, "id": 34}, {"text": "red", "start": 138, "end": 141, "id": 35}, {"text": "arrows", "start": 142, "end": 148, "id": 36}, {"text": ")", "start": 148, "end": 149, "id": 37}, {"text": "but", "start": 150, "end": 153, "id": 38}, {"text": "no", "start": 154, "end": 156, "id": 39}, {"text": "corresponding", "start": 157, "end": 170, "id": 40}, {"text": "green", "start": 171, "end": 176, "id": 41}, {"text": "-", "start": 176, "end": 177, "id": 42}, {"text": "coded", "start": 177, "end": 182, "id": 43}, {"text": "(", "start": 183, "end": 184, "id": 44}, {"text": "MSU", "start": 184, "end": 187, "id": 45}, {"text": ")", "start": 187, "end": 188, "id": 46}, {"text": "deposits", "start": 189, "end": 197, "id": 47}, {"text": "in", "start": 198, "end": 200, "id": 48}, {"text": "or", "start": 201, "end": 203, "id": 49}, {"text": "around", "start": 204, "end": 210, "id": 50}, {"text": "the", "start": 211, "end": 214, "id": 51}, {"text": "erosion", "start": 215, "end": 222, "id": 52}, {"text": "on", "start": 223, "end": 225, "id": 53}, {"text": "the", "start": 226, "end": 229, "id": 54}, {"text": "DECT", "start": 230, "end": 234, "id": 55}, {"text": "images", "start": 235, "end": 241, "id": 56}, {"text": "(", "start": 242, "end": 243, "id": 57}, {"text": "panels", "start": 243, "end": 249, "id": 58}, {"text": "(", "start": 250, "end": 251, "id": 59}, {"text": "c", "start": 251, "end": 252, "id": 60}, {"text": "-", "start": 252, "end": 253, "id": 61}, {"text": "d", "start": 253, "end": 254, "id": 62}, {"text": ")", "start": 254, "end": 255, "id": 63}, {"text": ")", "start": 255, "end": 256, "id": 64}]}
{"pdf_hash": "4a719e04e25ab39f2afa1c6f3467d01017d9ce56", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. Pre- and post-operative images of a\u00a0patient who received UPSFC. A\u00a0\u2013 The preoperative image of CT scan for huge disc herniation at right side. B \u2013 Preoperative T2 WI MRI scanning for protrusion of intervertebral disc at L5/S1. C \u2013 X-ray image of lateral projection detected 1 week after operation. No alteration in the position of nail stick and cage was detected. 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{"pdf_hash": "c08561bd40b1d1c2d6e80240731082551c493210", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 a Gross feature of gastric-type adenocarcinoma (GAS). The cervix was partially or entirely replaced by a firm indurated mass imparting a barrel-shaped enlargement. b-c, Well-differentiated GAS showed haphazardly arranged and irregularly shaped neoplastic glands, which were usually associated with a desmoplastic stromal reaction. 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{"pdf_hash": "d3edd139a3bf74c41da91fb691c732d043d19dff", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2: Brain MRI of patient no. 13. T2WI (a and b) showed symmetrical lesions in the bilateral basal ganglia, thalamus, and periventricular white matter; MRS (c) showed raised lactate peak in lesion of the basal ganglia. MRI: Magnetic resonance imaging; T2WI: T2\u2011weighted images; MRS: Magnetic resonance spectroscopy.", "width": 1058, "height": 390, "subcaptions": {"a": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "c9f6f71b-f4af-40d9-ad92-51f49ec7f9bf", "label": "a", "points": [[356.9, 357.7], [356.9, 5], [35.9, 5], [35.9, 357.7]], "color": "yellow"}, {"id": "1b21f9d1-86dd-4ce2-b1ca-57f9e11b5e5f", "label": "a", "points": [[366.9, 1.7], [366.9, 362.7], [687.8, 362.7], [687.8, 1.7]], "color": "cyan"}, {"id": "f0a160d5-845c-44f1-a986-192a3c714284", "label": "c", "points": [[692.8, 1.7], [692.8, 359.4], [1023.8, 359.4], [1023.8, 1.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Brain", "start": 10, "end": 15, "id": 3}, {"text": "MRI", "start": 16, "end": 19, "id": 4}, {"text": "of", "start": 20, "end": 22, "id": 5}, {"text": "patient", "start": 23, "end": 30, "id": 6}, {"text": "no", "start": 31, "end": 33, "id": 7}, {"text": ".", "start": 33, "end": 34, "id": 8}, {"text": "13", "start": 35, "end": 37, "id": 9}, {"text": ".", "start": 37, "end": 38, "id": 10}, {"text": "T2WI", "start": 39, "end": 43, "id": 11}, {"text": "(", "start": 44, "end": 45, "id": 12}, {"text": "a", "start": 45, "end": 46, "id": 13}, {"text": "and", "start": 47, "end": 50, "id": 14}, {"text": "b", "start": 51, "end": 52, "id": 15}, {"text": ")", "start": 52, "end": 53, "id": 16}, {"text": "showed", "start": 54, "end": 60, "id": 17}, {"text": "symmetrical", "start": 61, "end": 72, "id": 18}, {"text": "lesions", "start": 73, "end": 80, "id": 19}, {"text": "in", "start": 81, "end": 83, "id": 20}, {"text": "the", "start": 84, "end": 87, "id": 21}, {"text": "bilateral", "start": 88, "end": 97, "id": 22}, {"text": "basal", "start": 98, "end": 103, "id": 23}, {"text": "ganglia", "start": 104, "end": 111, "id": 24}, {"text": ",", "start": 111, "end": 112, "id": 25}, {"text": "thalamus", "start": 113, "end": 121, "id": 26}, {"text": ",", "start": 121, "end": 122, "id": 27}, {"text": "and", "start": 123, "end": 126, "id": 28}, {"text": "periventricular", "start": 127, "end": 142, "id": 29}, {"text": "white", "start": 143, "end": 148, "id": 30}, {"text": "matter", "start": 149, "end": 155, "id": 31}, {"text": ";", "start": 155, "end": 156, "id": 32}, {"text": "MRS", "start": 157, "end": 160, "id": 33}, {"text": "(", "start": 161, "end": 162, "id": 34}, {"text": "c", "start": 162, "end": 163, "id": 35}, {"text": ")", "start": 163, "end": 164, "id": 36}, {"text": "showed", "start": 165, "end": 171, "id": 37}, {"text": "raised", "start": 172, "end": 178, "id": 38}, {"text": "lactate", "start": 179, "end": 186, "id": 39}, {"text": "peak", "start": 187, "end": 191, "id": 40}, {"text": "in", "start": 192, "end": 194, "id": 41}, {"text": "lesion", "start": 195, "end": 201, "id": 42}, {"text": "of", "start": 202, "end": 204, "id": 43}, {"text": "the", "start": 205, "end": 208, "id": 44}, {"text": "basal", "start": 209, "end": 214, "id": 45}, {"text": "ganglia", "start": 215, "end": 222, "id": 46}, {"text": ".", "start": 222, "end": 223, "id": 47}, {"text": "MRI", "start": 224, "end": 227, "id": 48}, {"text": ":", "start": 227, "end": 228, "id": 49}, {"text": "Magnetic", "start": 229, "end": 237, "id": 50}, {"text": "resonance", "start": 238, "end": 247, "id": 51}, {"text": "imaging", "start": 248, "end": 255, "id": 52}, {"text": ";", "start": 255, "end": 256, "id": 53}, {"text": "T2WI", "start": 257, "end": 261, "id": 54}, {"text": ":", "start": 261, "end": 262, "id": 55}, {"text": "T2\u2011weighted", "start": 263, "end": 274, "id": 56}, {"text": "images", "start": 275, "end": 281, "id": 57}, {"text": ";", "start": 281, "end": 282, "id": 58}, {"text": "MRS", "start": 283, "end": 286, "id": 59}, {"text": ":", "start": 286, "end": 287, "id": 60}, {"text": "Magnetic", "start": 288, "end": 296, "id": 61}, {"text": "resonance", "start": 297, "end": 306, "id": 62}, {"text": "spectroscopy", "start": 307, "end": 319, "id": 63}, {"text": ".", "start": 319, "end": 320, "id": 64}]}
{"pdf_hash": "7d3b018fbbe0a904c0feae0dd5e8cd337d434566", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. 70 keV contrast-enhanced monochromatic and GSI images in a 22-year-old woman with papillary throid carcinoma. GSI images show that IC and \u03bb HU in metastatic lymph nodes are significantly higher than those of SC, SCC and lymphoma groups. (a) An axial CT image shows a right level II metastatic enlarged lymph node (white arrow). (b) An iodine-based material-decomposition image shows that the IC of the metastatic lymph nodes was 45.05 \u00d7 10 2 \u03bc g/cm 3 (L2: area, 42.52 mm 2 ). 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{"pdf_hash": "0e14ca2143ff55e09c1def0d8c378da61628837e", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4 - Sagittal reconstruction of soft tissue window and bone window computed tomography scans (A and B, respectively) of the thoracic spine showing hypertrophied and calcified ligamenta flava causing spinal canal narrowing, which is most evident at T6, T10, and T11.", "width": 948, "height": 656, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 12, 13, 14, 15, 16, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "b": [3, 4, 5, 10, 11, 12, 13, 14, 15, 18, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "e0489721-1832-476c-b33e-0faabd4eb35c", "label": "a", "points": [[4.7, 3.5], [4.7, 655], [469, 655], [469, 3.5]], "color": "yellow"}, {"id": "e633a43b-cd78-465e-b209-7b3e6d95f135", "label": "b", "points": [[472, 0.5], [472, 650.5], [945.3, 650.5], [945.3, 0.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "-", "start": 9, "end": 10, "id": 2}, {"text": "Sagittal", "start": 11, "end": 19, "id": 3}, {"text": "reconstruction", "start": 20, "end": 34, "id": 4}, {"text": "of", "start": 35, "end": 37, "id": 5}, {"text": "soft", "start": 38, "end": 42, "id": 6}, {"text": "tissue", "start": 43, "end": 49, "id": 7}, {"text": "window", "start": 50, "end": 56, "id": 8}, {"text": "and", "start": 57, "end": 60, "id": 9}, {"text": "bone", "start": 61, "end": 65, "id": 10}, {"text": "window", "start": 66, "end": 72, "id": 11}, {"text": "computed", "start": 73, "end": 81, "id": 12}, {"text": "tomography", "start": 82, "end": 92, "id": 13}, {"text": "scans", "start": 93, "end": 98, "id": 14}, {"text": "(", "start": 99, "end": 100, "id": 15}, {"text": "A", "start": 100, "end": 101, "id": 16}, {"text": "and", "start": 102, "end": 105, "id": 17}, {"text": "B", "start": 106, "end": 107, "id": 18}, {"text": ",", "start": 107, "end": 108, "id": 19}, {"text": "respectively", "start": 109, "end": 121, "id": 20}, {"text": ")", "start": 121, "end": 122, "id": 21}, {"text": "of", "start": 123, "end": 125, "id": 22}, {"text": "the", "start": 126, "end": 129, "id": 23}, {"text": "thoracic", "start": 130, "end": 138, "id": 24}, {"text": "spine", "start": 139, "end": 144, "id": 25}, {"text": "showing", "start": 145, "end": 152, "id": 26}, {"text": "hypertrophied", "start": 153, "end": 166, "id": 27}, {"text": "and", "start": 167, "end": 170, "id": 28}, {"text": "calcified", "start": 171, "end": 180, "id": 29}, {"text": "ligamenta", "start": 181, "end": 190, "id": 30}, {"text": "flava", "start": 191, "end": 196, "id": 31}, {"text": "causing", "start": 197, "end": 204, "id": 32}, {"text": "spinal", "start": 205, "end": 211, "id": 33}, {"text": "canal", "start": 212, "end": 217, "id": 34}, {"text": "narrowing", "start": 218, "end": 227, "id": 35}, {"text": ",", "start": 227, "end": 228, "id": 36}, {"text": "which", "start": 229, "end": 234, "id": 37}, {"text": "is", "start": 235, "end": 237, "id": 38}, {"text": "most", "start": 238, "end": 242, "id": 39}, {"text": "evident", "start": 243, "end": 250, "id": 40}, {"text": "at", "start": 251, "end": 253, "id": 41}, {"text": "T6", "start": 254, "end": 256, "id": 42}, {"text": ",", "start": 256, "end": 257, "id": 43}, {"text": "T10", "start": 258, "end": 261, "id": 44}, {"text": ",", "start": 261, "end": 262, "id": 45}, {"text": "and", "start": 263, "end": 266, "id": 46}, {"text": "T11", "start": 267, "end": 270, "id": 47}, {"text": ".", "start": 270, "end": 271, "id": 48}]}
{"pdf_hash": "3f772e3eb010709c28105873af0d14c80e9f9a34", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. a, b. A 72-year-old man with a history of coronary artery bypass grafts. Axial CT in 2006 (a) demonstrated a 15-mm lymph node in station 4R (arrows). No other lymphadenopathy was identified. No underlying etiology was elucidated. Axial CT in 2010 (b) demonstrated no change in the mediastinal lymphadenopathy over a four-year period.", "width": 936, "height": 460, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "b": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71]}, "subfigures": [{"id": "01da0457-791c-4e7c-9766-19a3901735f3", "label": "a", "points": [[0.1, 32.3], [0.1, 430], [448.1, 430], [448.1, 32.3]], "color": "yellow"}, {"id": "36713c3f-8aac-45af-972f-f326d3e35c21", "label": "b", "points": [[486.5, 32.3], [486.5, 428.5], [928.6, 428.5], [928.6, 32.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "b.", "start": 13, "end": 15, "id": 5}, {"text": "A", "start": 16, "end": 17, "id": 6}, {"text": "72-year", "start": 18, "end": 25, "id": 7}, {"text": "-", "start": 25, "end": 26, "id": 8}, {"text": "old", "start": 26, "end": 29, "id": 9}, {"text": "man", "start": 30, "end": 33, "id": 10}, {"text": "with", "start": 34, "end": 38, "id": 11}, {"text": "a", "start": 39, "end": 40, "id": 12}, {"text": "history", "start": 41, "end": 48, "id": 13}, {"text": "of", "start": 49, "end": 51, "id": 14}, {"text": "coronary", "start": 52, "end": 60, "id": 15}, {"text": "artery", "start": 61, "end": 67, "id": 16}, {"text": "bypass", "start": 68, "end": 74, "id": 17}, {"text": "grafts", "start": 75, "end": 81, "id": 18}, {"text": ".", "start": 81, "end": 82, "id": 19}, {"text": "Axial", "start": 83, "end": 88, "id": 20}, {"text": "CT", "start": 89, "end": 91, "id": 21}, {"text": "in", "start": 92, "end": 94, "id": 22}, {"text": "2006", "start": 95, "end": 99, "id": 23}, {"text": "(", "start": 100, "end": 101, "id": 24}, {"text": "a", "start": 101, "end": 102, "id": 25}, {"text": ")", "start": 102, "end": 103, "id": 26}, {"text": "demonstrated", "start": 104, "end": 116, "id": 27}, {"text": "a", "start": 117, "end": 118, "id": 28}, {"text": "15-mm", "start": 119, "end": 124, "id": 29}, {"text": "lymph", "start": 125, "end": 130, "id": 30}, {"text": "node", "start": 131, "end": 135, "id": 31}, {"text": "in", "start": 136, "end": 138, "id": 32}, {"text": "station", "start": 139, "end": 146, "id": 33}, {"text": "4R", "start": 147, "end": 149, "id": 34}, {"text": "(", "start": 150, "end": 151, "id": 35}, {"text": "arrows", "start": 151, "end": 157, "id": 36}, {"text": ")", "start": 157, "end": 158, "id": 37}, {"text": ".", "start": 158, "end": 159, "id": 38}, {"text": "No", "start": 160, "end": 162, "id": 39}, {"text": "other", "start": 163, "end": 168, "id": 40}, {"text": "lymphadenopathy", "start": 169, "end": 184, "id": 41}, {"text": "was", "start": 185, "end": 188, "id": 42}, {"text": "identified", "start": 189, "end": 199, "id": 43}, {"text": ".", "start": 199, "end": 200, "id": 44}, {"text": "No", "start": 201, "end": 203, "id": 45}, {"text": "underlying", "start": 204, "end": 214, "id": 46}, {"text": "etiology", "start": 215, "end": 223, "id": 47}, {"text": "was", "start": 224, "end": 227, "id": 48}, {"text": "elucidated", "start": 228, "end": 238, "id": 49}, {"text": ".", "start": 238, "end": 239, "id": 50}, {"text": "Axial", "start": 240, "end": 245, "id": 51}, {"text": "CT", "start": 246, "end": 248, "id": 52}, {"text": "in", "start": 249, "end": 251, "id": 53}, {"text": "2010", "start": 252, "end": 256, "id": 54}, {"text": "(", "start": 257, "end": 258, "id": 55}, {"text": "b", "start": 258, "end": 259, "id": 56}, {"text": ")", "start": 259, "end": 260, "id": 57}, {"text": "demonstrated", "start": 261, "end": 273, "id": 58}, {"text": "no", "start": 274, "end": 276, "id": 59}, {"text": "change", "start": 277, "end": 283, "id": 60}, {"text": "in", "start": 284, "end": 286, "id": 61}, {"text": "the", "start": 287, "end": 290, "id": 62}, {"text": "mediastinal", "start": 291, "end": 302, "id": 63}, {"text": "lymphadenopathy", "start": 303, "end": 318, "id": 64}, {"text": "over", "start": 319, "end": 323, "id": 65}, {"text": "a", "start": 324, "end": 325, "id": 66}, {"text": "four", "start": 326, "end": 330, "id": 67}, {"text": "-", "start": 330, "end": 331, "id": 68}, {"text": "year", "start": 331, "end": 335, "id": 69}, {"text": "period", "start": 336, "end": 342, "id": 70}, {"text": ".", "start": 342, "end": 343, "id": 71}]}
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{"pdf_hash": "5802de4b39127c2f84bd8e67855cc9b1600f2af4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A: Ultrasound showing a septated cystic mass in the left hypochondrium without vascularity on the Doppler flow study (arrow). B: CT of the abdomen, showing a mass in the stomach wall (arrowhead). Stomach filled with contrast material (asterisk).", "width": 1076, "height": 388, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52]}, "subfigures": [{"id": "cd0a8410-2886-492b-9304-ac545bc9fde4", "label": "a", "points": [[6, 3.1], [6, 383.9], [527.9, 383.9], [527.9, 3.1]], "color": "yellow"}, {"id": "ba776901-2791-4899-a98a-c19da4ba4007", "label": "b", "points": [[538.1, 3.1], [538.1, 380.5], [1042.9, 380.5], [1042.9, 3.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ":", "start": 11, "end": 12, "id": 4}, {"text": "Ultrasound", "start": 13, "end": 23, "id": 5}, {"text": "showing", "start": 24, "end": 31, "id": 6}, {"text": "a", "start": 32, "end": 33, "id": 7}, {"text": "septated", "start": 34, "end": 42, "id": 8}, {"text": "cystic", "start": 43, "end": 49, "id": 9}, {"text": "mass", "start": 50, "end": 54, "id": 10}, {"text": "in", "start": 55, "end": 57, "id": 11}, {"text": "the", "start": 58, "end": 61, "id": 12}, {"text": "left", "start": 62, "end": 66, "id": 13}, {"text": "hypochondrium", "start": 67, "end": 80, "id": 14}, {"text": "without", "start": 81, "end": 88, "id": 15}, {"text": "vascularity", "start": 89, "end": 100, "id": 16}, {"text": "on", "start": 101, "end": 103, "id": 17}, {"text": "the", "start": 104, "end": 107, "id": 18}, {"text": "Doppler", "start": 108, "end": 115, "id": 19}, {"text": "flow", "start": 116, "end": 120, "id": 20}, {"text": "study", "start": 121, "end": 126, "id": 21}, {"text": "(", "start": 127, "end": 128, "id": 22}, {"text": "arrow", "start": 128, "end": 133, "id": 23}, {"text": ")", "start": 133, "end": 134, "id": 24}, {"text": ".", "start": 134, "end": 135, "id": 25}, {"text": "B", "start": 136, "end": 137, "id": 26}, {"text": ":", "start": 137, "end": 138, "id": 27}, {"text": "CT", "start": 139, "end": 141, "id": 28}, {"text": "of", "start": 142, "end": 144, "id": 29}, {"text": "the", "start": 145, "end": 148, "id": 30}, {"text": "abdomen", "start": 149, "end": 156, "id": 31}, {"text": ",", "start": 156, "end": 157, "id": 32}, {"text": "showing", "start": 158, "end": 165, "id": 33}, {"text": "a", "start": 166, "end": 167, "id": 34}, {"text": "mass", "start": 168, "end": 172, "id": 35}, {"text": "in", "start": 173, "end": 175, "id": 36}, {"text": "the", "start": 176, "end": 179, "id": 37}, {"text": "stomach", "start": 180, "end": 187, "id": 38}, {"text": "wall", "start": 188, "end": 192, "id": 39}, {"text": "(", "start": 193, "end": 194, "id": 40}, {"text": "arrowhead", "start": 194, "end": 203, "id": 41}, {"text": ")", "start": 203, "end": 204, "id": 42}, {"text": ".", "start": 204, "end": 205, "id": 43}, {"text": "Stomach", "start": 206, "end": 213, "id": 44}, {"text": "filled", "start": 214, "end": 220, "id": 45}, {"text": "with", "start": 221, "end": 225, "id": 46}, {"text": "contrast", "start": 226, "end": 234, "id": 47}, {"text": "material", "start": 235, "end": 243, "id": 48}, {"text": "(", "start": 244, "end": 245, "id": 49}, {"text": "asterisk", "start": 245, "end": 253, "id": 50}, {"text": ")", "start": 253, "end": 254, "id": 51}, {"text": ".", "start": 254, "end": 255, "id": 52}]}
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{"pdf_hash": "c7ba19aa42e60be89aa59de044f24038789ddc95", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5 (A) Sagittal slices showing the eight ROIs masks generated from cortical endpoints of tracked fiber pathways from analysis shown in Figure 4. These ROIs were used as masks for resting state functional connectivity analysis on the subset of the sample (N \u00bc 110) that had viable resting state fMRI data. Variation in FA within the SNI (Div) related cluster correlated with variation in functional connectivity between a region on the right medial wall of the SFG and a region near the right NAcc (lower row). ACC, anterior cingulate cortex; PCC, posterior cingulate cortex; NAcc, nucleus accumbens; vmPFC, ventromedial prefrontal cortex; SFG, superior frontal gyrus; R, right; L, left. (B) Mediation analysis showing how FA and RD served as indirect pathways linking SNI (Div) to functional connectivity of the significant corticostriatal pathway identified in A. 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{"pdf_hash": "0f072ea4d56f80f61233fc47ffd47637c46922da", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Computed tomography of an intramuscular hemorrhage of the right quadriceps femoris muscle in a 53-year-old male patient with a spontaneous right-thigh hematoma and mild hemophilia A. An image taken at admission (A) and an image taken on day 5, which shows the worsening of the hemorrhage (B).", "width": 1102, "height": 478, "subcaptions": {"a": [33, 34, 35, 36, 37, 38, 39, 40], "b": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "0b2085fe-b25a-4dff-9b7b-76434255c65e", "label": "a", "points": [[9.2, 69.4], [9.2, 445.4], [524.5, 445.4], [524.5, 69.4]], "color": "yellow"}, {"id": "d31935bb-3cf4-4850-bd80-779d07cc2004", "label": "b", "points": [[535, 74.6], [535, 436.7], [1100.8, 436.7], [1100.8, 74.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomography", "start": 19, "end": 29, "id": 4}, {"text": "of", "start": 30, "end": 32, "id": 5}, {"text": "an", "start": 33, "end": 35, "id": 6}, {"text": "intramuscular", "start": 36, "end": 49, "id": 7}, {"text": "hemorrhage", "start": 50, "end": 60, "id": 8}, {"text": "of", "start": 61, "end": 63, "id": 9}, {"text": "the", "start": 64, "end": 67, "id": 10}, {"text": "right", "start": 68, "end": 73, "id": 11}, {"text": "quadriceps", "start": 74, "end": 84, "id": 12}, {"text": "femoris", "start": 85, "end": 92, "id": 13}, {"text": "muscle", "start": 93, "end": 99, "id": 14}, {"text": "in", "start": 100, "end": 102, "id": 15}, {"text": "a", "start": 103, "end": 104, "id": 16}, {"text": "53-year", "start": 105, "end": 112, "id": 17}, {"text": "-", "start": 112, "end": 113, "id": 18}, {"text": "old", "start": 113, "end": 116, "id": 19}, {"text": "male", "start": 117, "end": 121, "id": 20}, {"text": "patient", "start": 122, "end": 129, "id": 21}, {"text": "with", "start": 130, "end": 134, "id": 22}, {"text": "a", "start": 135, "end": 136, "id": 23}, {"text": "spontaneous", "start": 137, "end": 148, "id": 24}, {"text": "right", "start": 149, "end": 154, "id": 25}, {"text": "-", "start": 154, "end": 155, "id": 26}, {"text": "thigh", "start": 155, "end": 160, "id": 27}, {"text": "hematoma", "start": 161, "end": 169, "id": 28}, {"text": "and", "start": 170, "end": 173, "id": 29}, {"text": "mild", "start": 174, "end": 178, "id": 30}, {"text": "hemophilia", "start": 179, "end": 189, "id": 31}, {"text": "A.", "start": 190, "end": 192, "id": 32}, {"text": "An", "start": 193, "end": 195, "id": 33}, {"text": "image", "start": 196, "end": 201, "id": 34}, {"text": "taken", "start": 202, "end": 207, "id": 35}, {"text": "at", "start": 208, "end": 210, "id": 36}, {"text": "admission", "start": 211, "end": 220, "id": 37}, {"text": "(", "start": 221, "end": 222, "id": 38}, {"text": "A", "start": 222, "end": 223, "id": 39}, {"text": ")", "start": 223, "end": 224, "id": 40}, {"text": "and", "start": 225, "end": 228, "id": 41}, {"text": "an", "start": 229, "end": 231, "id": 42}, {"text": "image", "start": 232, "end": 237, "id": 43}, {"text": "taken", "start": 238, "end": 243, "id": 44}, {"text": "on", "start": 244, "end": 246, "id": 45}, {"text": "day", "start": 247, "end": 250, "id": 46}, {"text": "5", "start": 251, "end": 252, "id": 47}, {"text": ",", "start": 252, "end": 253, "id": 48}, {"text": "which", "start": 254, "end": 259, "id": 49}, {"text": "shows", "start": 260, "end": 265, "id": 50}, {"text": "the", "start": 266, "end": 269, "id": 51}, {"text": "worsening", "start": 270, "end": 279, "id": 52}, {"text": "of", "start": 280, "end": 282, "id": 53}, {"text": "the", "start": 283, "end": 286, "id": 54}, {"text": "hemorrhage", "start": 287, "end": 297, "id": 55}, {"text": "(", "start": 298, "end": 299, "id": 56}, {"text": "B", "start": 299, "end": 300, "id": 57}, {"text": ")", "start": 300, "end": 301, "id": 58}, {"text": ".", "start": 301, "end": 302, "id": 59}]}
{"pdf_hash": "443f96a18ea71ff24c65cb4ccaf7b0b7508b8c2f", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 a Lateral radiograph of the lumbar spine of a 6-year-old girl with a painful osteolytic lesion of the L2 vertebral body with vertebral plana deformity. CT-guided frozen section biopsy showed eosinophilic granuloma; intralesional methylprednisolone injection was performed. b Lateral radiograph of the lumbar spine shows complete reconstitution of the lesion 7 years after diagnosis and treatment", "width": 1182, "height": 886, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "b": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65]}, "subfigures": [{"id": "8b6dc095-6434-4250-9710-a957aa458834", "label": "a", "points": [[10.3, 5.3], [10.3, 879.1], [622.8, 879.1], [622.8, 5.3]], "color": "yellow"}, {"id": "c6236d88-1f4d-414d-85f7-5873f589eb57", "label": "b", "points": [[637.7, 3.4], [637.7, 879.1], [1173.6, 879.1], [1173.6, 3.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Lateral", "start": 9, "end": 16, "id": 4}, {"text": "radiograph", "start": 17, "end": 27, "id": 5}, {"text": "of", "start": 28, "end": 30, "id": 6}, {"text": "the", "start": 31, "end": 34, "id": 7}, {"text": "lumbar", "start": 35, "end": 41, "id": 8}, {"text": "spine", "start": 42, "end": 47, "id": 9}, {"text": "of", "start": 48, "end": 50, "id": 10}, {"text": "a", "start": 51, "end": 52, "id": 11}, {"text": "6-year", "start": 53, "end": 59, "id": 12}, {"text": "-", "start": 59, "end": 60, "id": 13}, {"text": "old", "start": 60, "end": 63, "id": 14}, {"text": "girl", "start": 64, "end": 68, "id": 15}, {"text": "with", "start": 69, "end": 73, "id": 16}, {"text": "a", "start": 74, "end": 75, "id": 17}, {"text": "painful", "start": 76, "end": 83, "id": 18}, {"text": "osteolytic", "start": 84, "end": 94, "id": 19}, {"text": "lesion", "start": 95, "end": 101, "id": 20}, {"text": "of", "start": 102, "end": 104, "id": 21}, {"text": "the", "start": 105, "end": 108, "id": 22}, {"text": "L2", "start": 109, "end": 111, "id": 23}, {"text": "vertebral", "start": 112, "end": 121, "id": 24}, {"text": "body", "start": 122, "end": 126, "id": 25}, {"text": "with", "start": 127, "end": 131, "id": 26}, {"text": "vertebral", "start": 132, "end": 141, "id": 27}, {"text": "plana", "start": 142, "end": 147, "id": 28}, {"text": "deformity", "start": 148, "end": 157, "id": 29}, {"text": ".", "start": 157, "end": 158, "id": 30}, {"text": "CT", "start": 159, "end": 161, "id": 31}, {"text": "-", "start": 161, "end": 162, "id": 32}, {"text": "guided", "start": 162, "end": 168, "id": 33}, {"text": "frozen", "start": 169, "end": 175, "id": 34}, {"text": "section", "start": 176, "end": 183, "id": 35}, {"text": "biopsy", "start": 184, "end": 190, "id": 36}, {"text": "showed", "start": 191, "end": 197, "id": 37}, {"text": "eosinophilic", "start": 198, "end": 210, "id": 38}, {"text": "granuloma", "start": 211, "end": 220, "id": 39}, {"text": ";", "start": 220, "end": 221, "id": 40}, {"text": "intralesional", "start": 222, "end": 235, "id": 41}, {"text": "methylprednisolone", "start": 236, "end": 254, "id": 42}, {"text": "injection", "start": 255, "end": 264, "id": 43}, {"text": "was", "start": 265, "end": 268, "id": 44}, {"text": "performed", "start": 269, "end": 278, "id": 45}, {"text": ".", "start": 278, "end": 279, "id": 46}, {"text": "b", "start": 280, "end": 281, "id": 47}, {"text": "Lateral", "start": 282, "end": 289, "id": 48}, {"text": "radiograph", "start": 290, "end": 300, "id": 49}, {"text": "of", "start": 301, "end": 303, "id": 50}, {"text": "the", "start": 304, "end": 307, "id": 51}, {"text": "lumbar", "start": 308, "end": 314, "id": 52}, {"text": "spine", "start": 315, "end": 320, "id": 53}, {"text": "shows", "start": 321, "end": 326, "id": 54}, {"text": "complete", "start": 327, "end": 335, "id": 55}, {"text": "reconstitution", "start": 336, "end": 350, "id": 56}, {"text": "of", "start": 351, "end": 353, "id": 57}, {"text": "the", "start": 354, "end": 357, "id": 58}, {"text": "lesion", "start": 358, "end": 364, "id": 59}, {"text": "7", "start": 365, "end": 366, "id": 60}, {"text": "years", "start": 367, "end": 372, "id": 61}, {"text": "after", "start": 373, "end": 378, "id": 62}, {"text": "diagnosis", "start": 379, "end": 388, "id": 63}, {"text": "and", "start": 389, "end": 392, "id": 64}, {"text": "treatment", "start": 393, "end": 402, "id": 65}]}
{"pdf_hash": "9ce38b595df5dba0c81bc406eaa94bcce6c69b56", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. A, Coronal ultrasound view of the parieto -occipital area posterior to the lateral ventricles of a 6 - day -old infant showing minimal, bilateral increase in periventricular echodensity. B, Same ultrasound view of the same patient at 73 days of age, showing the development of bilateral cystic PVL.", "width": 648, "height": 1164, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "b5ce9097-da14-44de-aafc-808de8c1ac5c", "label": "a", "points": [[1, 4.1], [1, 567.1], [644.9, 567.1], [644.9, 4.1]], "color": "yellow"}, {"id": "0cc93396-2e4b-4092-9c68-59bc68f1ec8f", "label": "b", "points": [[644.9, 601.9], [644.9, 1158.8], [2, 1158.8], [2, 601.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "Coronal", "start": 13, "end": 20, "id": 5}, {"text": "ultrasound", "start": 21, "end": 31, "id": 6}, {"text": "view", "start": 32, "end": 36, "id": 7}, {"text": "of", "start": 37, "end": 39, "id": 8}, {"text": "the", "start": 40, "end": 43, "id": 9}, {"text": "parieto", "start": 44, "end": 51, "id": 10}, {"text": "-occipital", "start": 52, "end": 62, "id": 11}, {"text": "area", "start": 63, "end": 67, "id": 12}, {"text": "posterior", "start": 68, "end": 77, "id": 13}, {"text": "to", "start": 78, "end": 80, "id": 14}, {"text": "the", "start": 81, "end": 84, "id": 15}, {"text": "lateral", "start": 85, "end": 92, "id": 16}, {"text": "ventricles", "start": 93, "end": 103, "id": 17}, {"text": "of", "start": 104, "end": 106, "id": 18}, {"text": "a", "start": 107, "end": 108, "id": 19}, {"text": "6", "start": 109, "end": 110, "id": 20}, {"text": "-", "start": 111, "end": 112, "id": 21}, {"text": "day", "start": 113, "end": 116, "id": 22}, {"text": "-old", "start": 117, "end": 121, "id": 23}, {"text": "infant", "start": 122, "end": 128, "id": 24}, {"text": "showing", "start": 129, "end": 136, "id": 25}, {"text": "minimal", "start": 137, "end": 144, "id": 26}, {"text": ",", "start": 144, "end": 145, "id": 27}, {"text": "bilateral", "start": 146, "end": 155, "id": 28}, {"text": "increase", "start": 156, "end": 164, "id": 29}, {"text": "in", "start": 165, "end": 167, "id": 30}, {"text": "periventricular", "start": 168, "end": 183, "id": 31}, {"text": "echodensity", "start": 184, "end": 195, "id": 32}, {"text": ".", "start": 195, "end": 196, "id": 33}, {"text": "B", "start": 197, "end": 198, "id": 34}, {"text": ",", "start": 198, "end": 199, "id": 35}, {"text": "Same", "start": 200, "end": 204, "id": 36}, {"text": "ultrasound", "start": 205, "end": 215, "id": 37}, {"text": "view", "start": 216, "end": 220, "id": 38}, {"text": "of", "start": 221, "end": 223, "id": 39}, {"text": "the", "start": 224, "end": 227, "id": 40}, {"text": "same", "start": 228, "end": 232, "id": 41}, {"text": "patient", "start": 233, "end": 240, "id": 42}, {"text": "at", "start": 241, "end": 243, "id": 43}, {"text": "73", "start": 244, "end": 246, "id": 44}, {"text": "days", "start": 247, "end": 251, "id": 45}, {"text": "of", "start": 252, "end": 254, "id": 46}, {"text": "age", "start": 255, "end": 258, "id": 47}, {"text": ",", "start": 258, "end": 259, "id": 48}, {"text": "showing", "start": 260, "end": 267, "id": 49}, {"text": "the", "start": 268, "end": 271, "id": 50}, {"text": "development", "start": 272, "end": 283, "id": 51}, {"text": "of", "start": 284, "end": 286, "id": 52}, {"text": "bilateral", "start": 287, "end": 296, "id": 53}, {"text": "cystic", "start": 297, "end": 303, "id": 54}, {"text": "PVL", "start": 304, "end": 307, "id": 55}, {"text": ".", "start": 307, "end": 308, "id": 56}]}
{"pdf_hash": "e7d0e52999c4c3520e570baf5a71ca297bd1f706", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5. Diffusion weighted imaging and diffusion tensor imaging scans from stroke patient (62-year-old man with right extremity weakness). A, B. Axial diffusion weighted imaging (A) and apparent diffusion coefficient (B) showed small hyperintense lesion on left thalamus and internal capsule. Lesion volume was 3.12 cm 3 . C, D. Fiber tracts reconstructed in 3-dimensional space were superimposed on fractional anisotrophy map (C) and directional encoded color map (D). E. 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{"pdf_hash": "ef036cddd44c24c35f8c68ddd7e03139685fe679", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Three-dimensional (3D) image of a master implant in a unilateral cranial defect. Preoperative axial 1-mm CT data are converted to 3D images (A). The image of the implant is generated by a digital subtraction mirror-image process (B) and developed into the 3D implant model (C). A B C", "width": 868, "height": 318, "subcaptions": {"a": [32, 33, 34, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [35, 36, 37, 38, 39, 40, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "3d516588-072a-40f7-b116-c27aca483e02", "label": "a", "points": [[4.8, 0.1], [4.8, 288.1], [280.4, 288.1], [280.4, 0.1]], "color": "yellow"}, {"id": "3e8dbc34-f5e5-4df6-be1a-f38c59f9cdd8", "label": "b", "points": [[294.2, 0.1], [294.2, 288.1], [578, 288.1], [578, 0.1]], "color": "cyan"}, {"id": "6bf37b2f-a6f6-46b9-8218-4f93309c3508", "label": "c", "points": [[586.2, 2.8], [586.2, 288.1], [864.6, 288.1], [864.6, 2.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Three", "start": 8, "end": 13, "id": 4}, {"text": "-", "start": 13, "end": 14, "id": 5}, {"text": "dimensional", "start": 14, "end": 25, "id": 6}, {"text": "(", "start": 26, "end": 27, "id": 7}, {"text": "3D", "start": 27, "end": 29, "id": 8}, {"text": ")", "start": 29, "end": 30, "id": 9}, {"text": "image", "start": 31, "end": 36, "id": 10}, {"text": "of", "start": 37, "end": 39, "id": 11}, {"text": "a", "start": 40, "end": 41, "id": 12}, {"text": "master", "start": 42, "end": 48, "id": 13}, {"text": "implant", "start": 49, "end": 56, "id": 14}, {"text": "in", "start": 57, "end": 59, "id": 15}, {"text": "a", "start": 60, "end": 61, "id": 16}, {"text": "unilateral", "start": 62, "end": 72, "id": 17}, {"text": "cranial", "start": 73, "end": 80, "id": 18}, {"text": "defect", "start": 81, "end": 87, "id": 19}, {"text": ".", "start": 87, "end": 88, "id": 20}, {"text": "Preoperative", "start": 89, "end": 101, "id": 21}, {"text": "axial", "start": 102, "end": 107, "id": 22}, {"text": "1-mm", "start": 108, "end": 112, "id": 23}, {"text": "CT", "start": 113, "end": 115, "id": 24}, {"text": "data", "start": 116, "end": 120, "id": 25}, {"text": "are", "start": 121, "end": 124, "id": 26}, {"text": "converted", "start": 125, "end": 134, "id": 27}, {"text": "to", "start": 135, "end": 137, "id": 28}, {"text": "3D", "start": 138, "end": 140, "id": 29}, {"text": "images", "start": 141, "end": 147, "id": 30}, {"text": "(", "start": 148, "end": 149, "id": 31}, {"text": "A", "start": 149, "end": 150, "id": 32}, {"text": ")", "start": 150, "end": 151, "id": 33}, {"text": ".", "start": 151, "end": 152, "id": 34}, {"text": "The", "start": 153, "end": 156, "id": 35}, {"text": "image", "start": 157, "end": 162, "id": 36}, {"text": "of", "start": 163, "end": 165, "id": 37}, {"text": "the", "start": 166, "end": 169, "id": 38}, {"text": "implant", "start": 170, "end": 177, "id": 39}, {"text": "is", "start": 178, "end": 180, "id": 40}, {"text": "generated", "start": 181, "end": 190, "id": 41}, {"text": "by", "start": 191, "end": 193, "id": 42}, {"text": "a", "start": 194, "end": 195, "id": 43}, {"text": "digital", "start": 196, "end": 203, "id": 44}, {"text": "subtraction", "start": 204, "end": 215, "id": 45}, {"text": "mirror", "start": 216, "end": 222, "id": 46}, {"text": "-", "start": 222, "end": 223, "id": 47}, {"text": "image", "start": 223, "end": 228, "id": 48}, {"text": "process", "start": 229, "end": 236, "id": 49}, {"text": "(", "start": 237, "end": 238, "id": 50}, {"text": "B", "start": 238, "end": 239, "id": 51}, {"text": ")", "start": 239, "end": 240, "id": 52}, {"text": "and", "start": 241, "end": 244, "id": 53}, {"text": "developed", "start": 245, "end": 254, "id": 54}, {"text": "into", "start": 255, "end": 259, "id": 55}, {"text": "the", "start": 260, "end": 263, "id": 56}, {"text": "3D", "start": 264, "end": 266, "id": 57}, {"text": "implant", "start": 267, "end": 274, "id": 58}, {"text": "model", "start": 275, "end": 280, "id": 59}, {"text": "(", "start": 281, "end": 282, "id": 60}, {"text": "C", "start": 282, "end": 283, "id": 61}, {"text": ")", "start": 283, "end": 284, "id": 62}, {"text": ".", "start": 284, "end": 285, "id": 63}, {"text": "A", "start": 286, "end": 287, "id": 64}, {"text": "B", "start": 288, "end": 289, "id": 65}, {"text": "C", "start": 290, "end": 291, "id": 66}]}
{"pdf_hash": "745166c44b8f358e448c8265343100c7bf055358", "fig_key": "Figure13", "fig_uri": "6-Figure13-1.png", "text": "Figure 13. (A} Electron micrograph of mine-dust quartz-based particle. (B,C} Elemental X-ray maps of same particle.", "width": 1436, "height": 442, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "873cfea8-24c6-4918-8def-e17e342c4de2", "label": "a", "points": [[9.5, 3], [9.5, 420.4], [451.8, 420.4], [451.8, 3]], "color": "yellow"}, {"id": "c1882aa4-6e83-41c9-b4d6-f90edd8a565a", "label": "b", "points": [[508.5, 3], [508.5, 431.8], [928.2, 431.8], [928.2, 3]], "color": "cyan"}, {"id": "3841eb23-1e03-4f5f-8e14-5ff76db72588", "label": "b", "points": [[1000.8, 12.1], [1000.8, 411.4], [1431.9, 411.4], [1431.9, 12.1]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "13", "start": 7, "end": 9, "id": 1}, {"text": ".", "start": 9, "end": 10, "id": 2}, {"text": "(", "start": 11, "end": 12, "id": 3}, {"text": "A", "start": 12, "end": 13, "id": 4}, {"text": "}", "start": 13, "end": 14, "id": 5}, {"text": "Electron", "start": 15, "end": 23, "id": 6}, {"text": "micrograph", "start": 24, "end": 34, "id": 7}, {"text": "of", "start": 35, "end": 37, "id": 8}, {"text": "mine", "start": 38, "end": 42, "id": 9}, {"text": "-", "start": 42, "end": 43, "id": 10}, {"text": "dust", "start": 43, "end": 47, "id": 11}, {"text": "quartz", "start": 48, "end": 54, "id": 12}, {"text": "-", "start": 54, "end": 55, "id": 13}, {"text": "based", "start": 55, "end": 60, "id": 14}, {"text": "particle", "start": 61, "end": 69, "id": 15}, {"text": ".", "start": 69, "end": 70, "id": 16}, {"text": "(", "start": 71, "end": 72, "id": 17}, {"text": "B", "start": 72, "end": 73, "id": 18}, {"text": ",", "start": 73, "end": 74, "id": 19}, {"text": "C", "start": 74, "end": 75, "id": 20}, {"text": "}", "start": 75, "end": 76, "id": 21}, {"text": "Elemental", "start": 77, "end": 86, "id": 22}, {"text": "X", "start": 87, "end": 88, "id": 23}, {"text": "-", "start": 88, "end": 89, "id": 24}, {"text": "ray", "start": 89, "end": 92, "id": 25}, {"text": "maps", "start": 93, "end": 97, "id": 26}, {"text": "of", "start": 98, "end": 100, "id": 27}, {"text": "same", "start": 101, "end": 105, "id": 28}, {"text": "particle", "start": 106, "end": 114, "id": 29}, {"text": ".", "start": 114, "end": 115, "id": 30}]}
{"pdf_hash": "bb2f23308a7e55bd7e3bfdb544e15b6c26ffb125", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 Chest computed tomography scans after trastuzumab therapy showing improvements of (a) consolidations in both the lower lobes and (b) the mediastinal mass.", "width": 846, "height": 296, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [23, 24, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "21243ab1-039c-4c4c-b7be-900e3e7fdc16", "label": "a", "points": [[31, 17.8], [31, 274.4], [417.2, 274.4], [417.2, 17.8]], "color": "yellow"}, {"id": "a9f69a70-0c0e-4769-b0db-cd1eb87a59ad", "label": "b", "points": [[423.9, 19.2], [423.9, 269.1], [816.9, 269.1], [816.9, 19.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Chest", "start": 7, "end": 12, "id": 3}, {"text": "computed", "start": 13, "end": 21, "id": 4}, {"text": "tomography", "start": 22, "end": 32, "id": 5}, {"text": "scans", "start": 33, "end": 38, "id": 6}, {"text": "after", "start": 39, "end": 44, "id": 7}, {"text": "trastuzumab", "start": 45, "end": 56, "id": 8}, {"text": "therapy", "start": 57, "end": 64, "id": 9}, {"text": "showing", "start": 65, "end": 72, "id": 10}, {"text": "improvements", "start": 73, "end": 85, "id": 11}, {"text": "of", "start": 86, "end": 88, "id": 12}, {"text": "(", "start": 89, "end": 90, "id": 13}, {"text": "a", "start": 90, "end": 91, "id": 14}, {"text": ")", "start": 91, "end": 92, "id": 15}, {"text": "consolidations", "start": 93, "end": 107, "id": 16}, {"text": "in", "start": 108, "end": 110, "id": 17}, {"text": "both", "start": 111, "end": 115, "id": 18}, {"text": "the", "start": 116, "end": 119, "id": 19}, {"text": "lower", "start": 120, "end": 125, "id": 20}, {"text": "lobes", "start": 126, "end": 131, "id": 21}, {"text": "and", "start": 132, "end": 135, "id": 22}, {"text": "(", "start": 136, "end": 137, "id": 23}, {"text": "b", "start": 137, "end": 138, "id": 24}, {"text": ")", "start": 138, "end": 139, "id": 25}, {"text": "the", "start": 140, "end": 143, "id": 26}, {"text": "mediastinal", "start": 144, "end": 155, "id": 27}, {"text": "mass", "start": 156, "end": 160, "id": 28}, {"text": ".", "start": 160, "end": 161, "id": 29}]}
{"pdf_hash": "b05c1943586a29c42cbf2ee7cc76ab23233e8757", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5 MRI images one and half months after the first debridement. T1-weighted sagittal image (left) shows hypointensity of L4 and L5 vertebral bodies with involvement of posterior elements. T2-weighted image shows heterogenous density similar to the preoperative image (right)", "width": 784, "height": 820, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46]}, "subfigures": [{"id": "36a27085-e9c7-4247-8c48-db35e37ea70d", "label": "a", "points": [[3.1, 1.2], [3.1, 817.4], [364.8, 817.4], [364.8, 1.2]], "color": "yellow"}, {"id": "f4bd3a60-2b1c-4186-9671-c880c779878e", "label": "b", "points": [[374.7, 3.7], [374.7, 816.2], [779.7, 816.2], [779.7, 3.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": "MRI", "start": 7, "end": 10, "id": 3}, {"text": "images", "start": 11, "end": 17, "id": 4}, {"text": "one", "start": 18, "end": 21, "id": 5}, {"text": "and", "start": 22, "end": 25, "id": 6}, {"text": "half", "start": 26, "end": 30, "id": 7}, {"text": "months", "start": 31, "end": 37, "id": 8}, {"text": "after", "start": 38, "end": 43, "id": 9}, {"text": "the", "start": 44, "end": 47, "id": 10}, {"text": "first", "start": 48, "end": 53, "id": 11}, {"text": "debridement", "start": 54, "end": 65, "id": 12}, {"text": ".", "start": 65, "end": 66, "id": 13}, {"text": "T1-weighted", "start": 67, "end": 78, "id": 14}, {"text": "sagittal", "start": 79, "end": 87, "id": 15}, {"text": "image", "start": 88, "end": 93, "id": 16}, {"text": "(", "start": 94, "end": 95, "id": 17}, {"text": "left", "start": 95, "end": 99, "id": 18}, {"text": ")", "start": 99, "end": 100, "id": 19}, {"text": "shows", "start": 101, "end": 106, "id": 20}, {"text": "hypointensity", "start": 107, "end": 120, "id": 21}, {"text": "of", "start": 121, "end": 123, "id": 22}, {"text": "L4", "start": 124, "end": 126, "id": 23}, {"text": "and", "start": 127, "end": 130, "id": 24}, {"text": "L5", "start": 131, "end": 133, "id": 25}, {"text": "vertebral", "start": 134, "end": 143, "id": 26}, {"text": "bodies", "start": 144, "end": 150, "id": 27}, {"text": "with", "start": 151, "end": 155, "id": 28}, {"text": "involvement", "start": 156, "end": 167, "id": 29}, {"text": "of", "start": 168, "end": 170, "id": 30}, {"text": "posterior", "start": 171, "end": 180, "id": 31}, {"text": "elements", "start": 181, "end": 189, "id": 32}, {"text": ".", "start": 189, "end": 190, "id": 33}, {"text": "T2-weighted", "start": 191, "end": 202, "id": 34}, {"text": "image", "start": 203, "end": 208, "id": 35}, {"text": "shows", "start": 209, "end": 214, "id": 36}, {"text": "heterogenous", "start": 215, "end": 227, "id": 37}, {"text": "density", "start": 228, "end": 235, "id": 38}, {"text": "similar", "start": 236, "end": 243, "id": 39}, {"text": "to", "start": 244, "end": 246, "id": 40}, {"text": "the", "start": 247, "end": 250, "id": 41}, {"text": "preoperative", "start": 251, "end": 263, "id": 42}, {"text": "image", "start": 264, "end": 269, "id": 43}, {"text": "(", "start": 270, "end": 271, "id": 44}, {"text": "right", "start": 271, "end": 276, "id": 45}, {"text": ")", "start": 276, "end": 277, "id": 46}]}
{"pdf_hash": "97d87ade9634700abb6f0197bac559def15cf40b", "fig_key": "Figure3", "fig_uri": "10-Figure3-1.png", "text": "Fig. 3. (a) High magnification of a longitudinal section of a phase II emu spermatid showing a nuclear constriction with an accumulation of microtubules and granular material (arrow) in the adjacent cytoplasm. Nucleus (N). (b) Late phase II rhea spermatid. The main morphological features include a cup-shaped acrosome (A), cytoplasmic collar (C) with a cranial extension of the circular manchette (thin arrows), post-acrosomal perinuclear theca (block arrows) showing localized concentration of finger-like elaborations (dashed oval) and shrinkage of the chromatin away from the inner nuclear membrane (stars). Endonuclear canal with perforatorium (En). (c) Phase II ostrich spermatid displaying the typical dumb-bell-shaped forming acrosome (thin arrow). The spermatid plasmalemma has been drawn over the acrosome (block arrows). (d) Phase II rhea spermatid displaying a crescent-shaped acrosome (thin arrows), translucent sub-acrosomal layer (white arrows) and the forming endonuclear canal (block arrow). 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{"pdf_hash": "ebcae7f2dc6f570e1266803f788a61b5485df985", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Chest X-ray (A), Chest CT (B), and 18 F-FDG PET-CT (C) scans at the initial presentation. Right pleural effusion with thickening in the right front pleura is observed. The increased uptake of FDG in the right front pleura, mediastinal organs, and metastases in the mediastinal lymph nodes was observed.", "width": 1182, "height": 364, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9], "b": [11, 12, 13, 14, 15], "c": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33]}, "subfigures": [{"id": "b40e18a9-af06-4d38-b8bd-219a8dbc713c", "label": "a", "points": [[4.7, 38.9], [4.7, 332.1], [322.2, 332.1], [322.2, 38.9]], "color": "yellow"}, {"id": "ac35e945-e433-43c8-9111-477ea4f37d48", "label": "b", "points": [[339, 46.4], [339, 330.2], [744.2, 330.2], [744.2, 46.4]], "color": "cyan"}, {"id": "5d26d970-65da-4ce8-8e78-0a2766729f7a", "label": "c", "points": [[761, 40.8], [761, 330.2], [1173.7, 330.2], [1173.7, 40.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Chest", "start": 10, "end": 15, "id": 3}, {"text": "X", "start": 16, "end": 17, "id": 4}, {"text": "-", "start": 17, "end": 18, "id": 5}, {"text": "ray", "start": 18, "end": 21, "id": 6}, {"text": "(", "start": 22, "end": 23, "id": 7}, {"text": "A", "start": 23, "end": 24, "id": 8}, {"text": ")", "start": 24, "end": 25, "id": 9}, {"text": ",", "start": 25, "end": 26, "id": 10}, {"text": "Chest", "start": 27, "end": 32, "id": 11}, {"text": "CT", "start": 33, "end": 35, "id": 12}, {"text": "(", "start": 36, "end": 37, "id": 13}, {"text": "B", "start": 37, "end": 38, "id": 14}, {"text": ")", "start": 38, "end": 39, "id": 15}, {"text": ",", "start": 39, "end": 40, "id": 16}, {"text": "and", "start": 41, "end": 44, "id": 17}, {"text": "18", "start": 45, "end": 47, "id": 18}, {"text": "F", "start": 48, "end": 49, "id": 19}, {"text": "-", "start": 49, "end": 50, "id": 20}, {"text": "FDG", "start": 50, "end": 53, "id": 21}, {"text": "PET", "start": 54, "end": 57, "id": 22}, {"text": "-", "start": 57, "end": 58, "id": 23}, {"text": "CT", "start": 58, "end": 60, "id": 24}, {"text": "(", "start": 61, "end": 62, "id": 25}, {"text": "C", "start": 62, "end": 63, "id": 26}, {"text": ")", "start": 63, "end": 64, "id": 27}, {"text": "scans", "start": 65, "end": 70, "id": 28}, {"text": "at", "start": 71, "end": 73, "id": 29}, {"text": "the", "start": 74, "end": 77, "id": 30}, {"text": "initial", "start": 78, "end": 85, "id": 31}, {"text": "presentation", "start": 86, "end": 98, "id": 32}, {"text": ".", "start": 98, "end": 99, "id": 33}, {"text": "Right", "start": 100, "end": 105, "id": 34}, {"text": "pleural", "start": 106, "end": 113, "id": 35}, {"text": "effusion", "start": 114, "end": 122, "id": 36}, {"text": "with", "start": 123, "end": 127, "id": 37}, {"text": "thickening", "start": 128, "end": 138, "id": 38}, {"text": "in", "start": 139, "end": 141, "id": 39}, {"text": "the", "start": 142, "end": 145, "id": 40}, {"text": "right", "start": 146, "end": 151, "id": 41}, {"text": "front", "start": 152, "end": 157, "id": 42}, {"text": "pleura", "start": 158, "end": 164, "id": 43}, {"text": "is", "start": 165, "end": 167, "id": 44}, {"text": "observed", "start": 168, "end": 176, "id": 45}, {"text": ".", "start": 176, "end": 177, "id": 46}, {"text": "The", "start": 178, "end": 181, "id": 47}, {"text": "increased", "start": 182, "end": 191, "id": 48}, {"text": "uptake", "start": 192, "end": 198, "id": 49}, {"text": "of", "start": 199, "end": 201, "id": 50}, {"text": "FDG", "start": 202, "end": 205, "id": 51}, {"text": "in", "start": 206, "end": 208, "id": 52}, {"text": "the", "start": 209, "end": 212, "id": 53}, {"text": "right", "start": 213, "end": 218, "id": 54}, {"text": "front", "start": 219, "end": 224, "id": 55}, {"text": "pleura", "start": 225, "end": 231, "id": 56}, {"text": ",", "start": 231, "end": 232, "id": 57}, {"text": "mediastinal", "start": 233, "end": 244, "id": 58}, {"text": "organs", "start": 245, "end": 251, "id": 59}, {"text": ",", "start": 251, "end": 252, "id": 60}, {"text": "and", "start": 253, "end": 256, "id": 61}, {"text": "metastases", "start": 257, "end": 267, "id": 62}, {"text": "in", "start": 268, "end": 270, "id": 63}, {"text": "the", "start": 271, "end": 274, "id": 64}, {"text": "mediastinal", "start": 275, "end": 286, "id": 65}, {"text": "lymph", "start": 287, "end": 292, "id": 66}, {"text": "nodes", "start": 293, "end": 298, "id": 67}, {"text": "was", "start": 299, "end": 302, "id": 68}, {"text": "observed", "start": 303, "end": 311, "id": 69}, {"text": ".", "start": 311, "end": 312, "id": 70}]}
{"pdf_hash": "443f52f6afefb08b34be9ed29e08baec9b1f887a", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 a, b Preoperative ultrasound biomicroscopy of the right eye. Preoperative ultrasound biomicroscopy of the right eye showing the cloudy cataractous lens suspended to the small ciliary processes (indicated with yellow arrowhead) by the apparently elongated suspensory ligaments (indicated with green arrowheads) caused by congenital enlargement of the anterior segment. The pectinate ligament (indicated with red arrowhead) was also observed at some places of anterior chamber angle by ultrasound biomicroscopy", "width": 1342, "height": 466, "subcaptions": {"a": [32, 33, 34, 35, 36, 37], "b": [59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80]}, "subfigures": [{"id": "2b3b9a0b-163c-43ed-a078-b42d767ae574", "label": "a", "points": [[20.2, 23], [20.2, 438.5], [656.2, 438.5], [656.2, 23]], "color": "yellow"}, {"id": "3fe79f55-d0ac-4142-910a-41eb0379c3f8", "label": "b", "points": [[671, 23], [671, 440.6], [1321.8, 440.6], [1321.8, 23]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": ",", "start": 8, "end": 9, "id": 4}, {"text": "b", "start": 10, "end": 11, "id": 5}, {"text": "Preoperative", "start": 12, "end": 24, "id": 6}, {"text": "ultrasound", 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The lesions involving T6 and T12 vertebral body shows slightly high signal intensity in T2- weighted MR images (B: sagittal, C: axial of T6, D: axial of T12) and homogenous enhancement in T1-weighted MR images after the administration of gadolinium (E: sagittal, F: axial of T6, G: axial of T12), Increased tracer activity is shown at the T6, T12 vertebra and epiphysis in whole body bone scan (H).", "width": 1336, "height": 720, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 69], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 58, 59, 60, 61, 62, 69], "d": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 64, 65, 66, 67, 68, 69], "e": [35, 36, 37, 38, 39, 40, 41, 42, 43, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 98], "f": 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{"pdf_hash": "21396e6a7f4d140e115d672e47ce367013304994", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig 1. Genetic ablation of GFAP and vimentin does not alter volume of ischemic lesion following dMCAO. (A) Location of ischemic injury at 9 weeks after dMCAO, covering most of the somatosensory cortex, as shown by NeuN-immunostaining in coronal sections from WT and GFAP -/-Vim -/-mice. Scale bar = 1 mm. (B) Mean volume of ischemic lesion in WT (n = 9) and GFAP -/-Vim -/-(n = 6) mice. Means \u00b1 SEM. 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{"pdf_hash": "f08f4302de74dd20f0d649b721e2b268ea60e164", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Fig. 3. Examples of C5\u20136 and C6\u20137 hard-disc herniations. Upper Left: Preoperative sagittal MR image. Upper Right: Axial CT scan obtained at C6\u20137, revealing a midline bone spur. Lower Left: Anteroposterior postoperative radiograph demonstrating cage position. Lower Right: Lateral postoperative radiograph.", "width": 668, "height": 792, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "c": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "d": [48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "417dfb2e-9642-44d6-986a-dda4be14c895", "label": "a", "points": [[1.6, -0.2], [1.6, 333.3], [268.6, 333.3], [268.6, -0.2]], "color": "yellow"}, {"id": "75564d7d-5857-42a6-91b4-c63a2344ce18", "label": "b", "points": [[274.9, 4], [274.9, 332.2], [666.4, 332.2], [666.4, 4]], "color": "cyan"}, {"id": "f15225cf-22a2-4b70-98f8-4bc668b8b91c", "label": "c", "points": [[1.6, 340.7], [1.6, 763.8], [323.5, 763.8], [323.5, 340.7]], "color": "magenta"}, {"id": "fcc3ca78-0606-4a90-9a8e-4d31162ad729", "label": "d", "points": [[330.9, 339.6], [330.9, 763.8], [661.2, 763.8], [661.2, 339.6]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Examples", "start": 8, "end": 16, "id": 4}, {"text": "of", "start": 17, "end": 19, "id": 5}, {"text": "C5\u20136", "start": 20, "end": 24, "id": 6}, {"text": "and", "start": 25, "end": 28, "id": 7}, {"text": "C6\u20137", "start": 29, "end": 33, "id": 8}, {"text": "hard", "start": 34, "end": 38, "id": 9}, {"text": "-", "start": 38, "end": 39, "id": 10}, {"text": "disc", "start": 39, "end": 43, "id": 11}, {"text": "herniations", "start": 44, "end": 55, "id": 12}, {"text": ".", "start": 55, "end": 56, "id": 13}, {"text": "Upper", "start": 57, "end": 62, "id": 14}, {"text": "Left", "start": 63, "end": 67, "id": 15}, {"text": ":", "start": 67, "end": 68, "id": 16}, {"text": "Preoperative", "start": 69, "end": 81, "id": 17}, {"text": "sagittal", "start": 82, "end": 90, "id": 18}, {"text": "MR", "start": 91, "end": 93, "id": 19}, {"text": "image", "start": 94, "end": 99, "id": 20}, {"text": ".", "start": 99, "end": 100, "id": 21}, {"text": "Upper", "start": 101, "end": 106, "id": 22}, {"text": "Right", "start": 107, "end": 112, "id": 23}, {"text": ":", "start": 112, "end": 113, "id": 24}, {"text": "Axial", "start": 114, "end": 119, "id": 25}, {"text": "CT", "start": 120, "end": 122, "id": 26}, {"text": "scan", "start": 123, "end": 127, "id": 27}, {"text": "obtained", "start": 128, "end": 136, "id": 28}, {"text": "at", "start": 137, "end": 139, "id": 29}, {"text": "C6\u20137", "start": 140, "end": 144, "id": 30}, {"text": ",", "start": 144, "end": 145, "id": 31}, {"text": "revealing", "start": 146, "end": 155, "id": 32}, {"text": "a", "start": 156, "end": 157, "id": 33}, {"text": "midline", "start": 158, "end": 165, "id": 34}, {"text": "bone", "start": 166, "end": 170, "id": 35}, {"text": "spur", "start": 171, "end": 175, "id": 36}, {"text": ".", "start": 175, "end": 176, "id": 37}, {"text": "Lower", "start": 177, "end": 182, "id": 38}, {"text": "Left", "start": 183, "end": 187, "id": 39}, {"text": ":", "start": 187, "end": 188, "id": 40}, {"text": "Anteroposterior", "start": 189, "end": 204, "id": 41}, {"text": "postoperative", "start": 205, "end": 218, "id": 42}, {"text": "radiograph", "start": 219, "end": 229, "id": 43}, {"text": "demonstrating", "start": 230, "end": 243, "id": 44}, {"text": "cage", "start": 244, "end": 248, "id": 45}, {"text": "position", "start": 249, "end": 257, "id": 46}, {"text": ".", "start": 257, "end": 258, "id": 47}, {"text": "Lower", "start": 259, "end": 264, "id": 48}, {"text": "Right", "start": 265, "end": 270, "id": 49}, {"text": ":", "start": 270, "end": 271, "id": 50}, {"text": "Lateral", "start": 272, "end": 279, "id": 51}, {"text": "postoperative", "start": 280, "end": 293, "id": 52}, {"text": "radiograph", "start": 294, "end": 304, "id": 53}, {"text": ".", "start": 304, "end": 305, "id": 54}]}
{"pdf_hash": "3756de862e8887cfed160527f60975832f178f1e", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "FIGURE 4 | Axial view centered on overlapping contrast images: green; (4) = (Post Real \u2212 Pre Real) > (Post Sham \u2212 Pre Sham) red-yellow; (Real) = Post Real > Pre Real, and blue-light blue; (Sham) = Post Sham < Pre Sham. (A) Parietal lobule/primary motor cortex (M1) activation (MNI: X = 2.16 mm, Y = \u221243.3 mm, Z = 61.8 mm) and (B) occipital cortex activation changes (MNI: X = \u221240.0 mm, Y = \u221280.0 mm, Z = 40.0 mm) are primarily a result of significant activation changes following real stimulation (red-yellow colormap). 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{"pdf_hash": "5df0b608463bc9dc1fe00c94551648310d6c7a7b", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Fig. 6. Comparison of beam-hardening artifacts between 165 mg/mL and 60 mg/mL iodine concentration for 72 keV virtual monochromatic spectral (VMS) images. Reconstructed coronal images from 72 keV VMS images. A. Iodine concentration was 165 mg/mL. Difference in CT number between iodinated contrast media and tendon ranged from 2950 to 3050 Hounsfield units (HU). Beam hardening artifacts was 27.5. B. Iodine concentration was 60 mg/mL. Difference in CT number between iodinated contrast media and tendon ranged from 1280 to 1380 HU. Beam hardening artifacts was 8.0. Window width was 400 and window level was 40 for both images.", "width": 1234, "height": 558, "subcaptions": {"a": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76], "b": [77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107]}, "subfigures": [{"id": "f67d347e-fda5-4957-90e7-950217317fb6", "label": "a", "points": [[28.3, 3.9], [28.3, 499.1], [607.3, 499.1], [607.3, 3.9]], "color": "yellow"}, {"id": "64a7368a-87a8-4f6b-950b-1564525e03c4", "label": "b", "points": [[622.8, 1.9], [622.8, 495.2], [1199.9, 495.2], [1199.9, 1.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "6", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Comparison", "start": 8, "end": 18, "id": 4}, {"text": "of", "start": 19, 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{"pdf_hash": "4be38abb25d0992f4af8df9fc87c76a110185f6c", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 Consecutive ultrasound scans, showing gradual thickening of vitreous exudate and posterior vitreous detachment (a\u2013c) and clear vitreous chamber after pars plana vitrectomy (d)", "width": 1244, "height": 286, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [32, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "37622731-3839-4382-9011-6ef9229871db", "label": "a", "points": [[0, 0], [0, 283], [300.7, 283], [300.7, 0]], "color": "yellow"}, {"id": "172b9ea1-35cf-4768-b464-0240badc98e6", "label": "a", "points": [[316.4, 2], [316.4, 281.1], [619.1, 281.1], [619.1, 2]], "color": "cyan"}, {"id": "e763e62d-9677-48d3-83c9-93a546b5165f", "label": "a", "points": [[634.8, 3.9], [634.8, 281.1], [929.6, 281.1], [929.6, 3.9]], "color": "magenta"}, {"id": "c4cf68ed-2ecf-4877-b034-47ec8711e4b8", "label": "b", "points": [[945.4, 0], [945.4, 285], [1240.2, 285], [1240.2, 0]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Consecutive", "start": 7, "end": 18, "id": 3}, {"text": "ultrasound", "start": 19, "end": 29, "id": 4}, {"text": "scans", "start": 30, "end": 35, "id": 5}, {"text": ",", "start": 35, "end": 36, "id": 6}, {"text": "showing", "start": 37, "end": 44, "id": 7}, {"text": "gradual", "start": 45, "end": 52, "id": 8}, {"text": "thickening", "start": 53, "end": 63, "id": 9}, {"text": "of", "start": 64, "end": 66, "id": 10}, {"text": "vitreous", "start": 67, "end": 75, "id": 11}, {"text": "exudate", "start": 76, "end": 83, "id": 12}, {"text": "and", "start": 84, "end": 87, "id": 13}, {"text": "posterior", "start": 88, "end": 97, "id": 14}, {"text": "vitreous", "start": 98, "end": 106, "id": 15}, {"text": "detachment", "start": 107, "end": 117, "id": 16}, {"text": "(", "start": 118, "end": 119, "id": 17}, {"text": "a", "start": 119, "end": 120, "id": 18}, {"text": "\u2013", "start": 120, "end": 121, "id": 19}, {"text": "c", "start": 121, "end": 122, "id": 20}, {"text": ")", "start": 122, "end": 123, "id": 21}, {"text": "and", "start": 124, "end": 127, "id": 22}, {"text": "clear", "start": 128, "end": 133, "id": 23}, {"text": "vitreous", "start": 134, "end": 142, "id": 24}, {"text": "chamber", "start": 143, "end": 150, "id": 25}, {"text": "after", "start": 151, "end": 156, "id": 26}, {"text": "pars", "start": 157, "end": 161, "id": 27}, {"text": "plana", "start": 162, "end": 167, "id": 28}, {"text": "vitrectomy", "start": 168, "end": 178, "id": 29}, {"text": "(", "start": 179, "end": 180, "id": 30}, {"text": "d", "start": 180, "end": 181, "id": 31}, {"text": ")", "start": 181, "end": 182, "id": 32}]}
{"pdf_hash": "e437498aab4e4281dcf0154c4c21f922aaf355b7", "fig_key": "Figure7", "fig_uri": "9-Figure7-1.png", "text": "Figure 7 Bilioenteric anastomosis between the jejuneum and biliary branches for hepatic segments 2-3 after right trisectionectomy associating liver partition and portal vein ligation for staged hepatectomy performed for hilar colangiocarcinoma showing. A, B: Magnetic resonance imaging single-shot turbo spin echo T2 weighted images acquired on transverse (A) and coronal planes (B) show absence of biliary dilatation; C: This finding was confirmed on thick maximum intensity projection coronally-reformatted image acquired on the hepatobiliary phase after gadoxetic acid administration, demonstrating regular flow of hyperintense bile.", "width": 1338, "height": 314, "subcaptions": {"a": [35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 59, 63, 64, 65, 66, 67], "b": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67], "c": [69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100]}, "subfigures": [{"id": "85615538-c38c-4bad-adad-549cd924d3b4", "label": "a", "points": [[-1, 1.8], [-1, 310.4], [415.4, 310.4], [415.4, 1.8]], "color": "yellow"}, {"id": "6b5619cf-79c9-455c-b400-ee56fb5f0ef1", 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{"pdf_hash": "5e8de3fd54d72d0051f75ae52ba82e1ed2ca63b2", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4. Fundus photographs and optical coherence tomography (OCT) scans of patient C-3. A, B: Bilateral vitelliform discs in the vitelliruptive stage with retinal pigment epithelium (RPE) dystrophy inferiorly to the macula. C, D: Macular optically empty lesions containing partially reabsorbed hyperreflective material. OD represents the right eye; OS represents the left eye.", "width": 1400, "height": 826, "subcaptions": {"a": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "4e36ff08-3d18-4b11-8ca9-a9214545b99e", "label": "a", "points": [[7, 44.2], [7, 592.8], [697.1, 592.8], [697.1, 44.2]], "color": "yellow"}, {"id": "1d723305-1573-47ce-90ce-deeb279d44d9", "label": "a", "points": [[714.8, 50.9], [714.8, 583.9], [1396, 583.9], [1396, 50.9]], "color": "cyan"}, {"id": "ed811d89-c69e-4061-b994-599cc858b784", "label": "b", "points": [[18.1, 610.4], [18.1, 789.6], [697.1, 789.6], [697.1, 610.4]], "color": "magenta"}, {"id": "008728c1-ab95-4306-841b-1ace5d1e8f4b", "label": "b", "points": [[717, 601.6], [717, 789.6], [1396, 789.6], [1396, 601.6]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Fundus", "start": 10, "end": 16, "id": 3}, {"text": "photographs", "start": 17, "end": 28, "id": 4}, {"text": "and", "start": 29, "end": 32, "id": 5}, {"text": "optical", "start": 33, "end": 40, "id": 6}, {"text": "coherence", "start": 41, "end": 50, "id": 7}, {"text": "tomography", "start": 51, "end": 61, "id": 8}, {"text": "(", "start": 62, "end": 63, "id": 9}, {"text": "OCT", "start": 63, "end": 66, "id": 10}, {"text": ")", "start": 66, "end": 67, "id": 11}, {"text": "scans", "start": 68, "end": 73, "id": 12}, {"text": "of", "start": 74, "end": 76, "id": 13}, {"text": "patient", "start": 77, "end": 84, "id": 14}, {"text": "C-3", "start": 85, "end": 88, "id": 15}, {"text": ".", "start": 88, "end": 89, "id": 16}, {"text": "A", "start": 90, "end": 91, "id": 17}, {"text": ",", "start": 91, "end": 92, "id": 18}, {"text": "B", "start": 93, "end": 94, "id": 19}, {"text": ":", "start": 94, "end": 95, "id": 20}, {"text": "Bilateral", "start": 96, "end": 105, "id": 21}, {"text": "vitelliform", "start": 106, "end": 117, "id": 22}, {"text": "discs", "start": 118, "end": 123, "id": 23}, {"text": "in", "start": 124, "end": 126, "id": 24}, {"text": "the", "start": 127, "end": 130, "id": 25}, {"text": "vitelliruptive", "start": 131, "end": 145, "id": 26}, {"text": "stage", "start": 146, "end": 151, "id": 27}, {"text": "with", "start": 152, "end": 156, "id": 28}, {"text": "retinal", "start": 157, "end": 164, "id": 29}, {"text": "pigment", "start": 165, "end": 172, "id": 30}, {"text": "epithelium", "start": 173, "end": 183, "id": 31}, {"text": "(", "start": 184, "end": 185, "id": 32}, {"text": "RPE", "start": 185, "end": 188, "id": 33}, {"text": ")", "start": 188, "end": 189, "id": 34}, {"text": "dystrophy", "start": 190, "end": 199, "id": 35}, {"text": "inferiorly", "start": 200, "end": 210, "id": 36}, {"text": "to", "start": 211, "end": 213, "id": 37}, {"text": "the", "start": 214, "end": 217, "id": 38}, {"text": "macula", "start": 218, "end": 224, "id": 39}, {"text": ".", "start": 224, "end": 225, "id": 40}, {"text": "C", "start": 226, "end": 227, "id": 41}, {"text": ",", "start": 227, "end": 228, "id": 42}, {"text": "D", "start": 229, "end": 230, "id": 43}, {"text": ":", "start": 230, "end": 231, "id": 44}, {"text": "Macular", "start": 232, "end": 239, "id": 45}, {"text": "optically", "start": 240, "end": 249, "id": 46}, {"text": "empty", "start": 250, "end": 255, "id": 47}, {"text": "lesions", "start": 256, "end": 263, "id": 48}, {"text": "containing", "start": 264, "end": 274, "id": 49}, {"text": "partially", "start": 275, "end": 284, "id": 50}, {"text": "reabsorbed", "start": 285, "end": 295, "id": 51}, {"text": "hyperreflective", "start": 296, "end": 311, "id": 52}, {"text": "material", "start": 312, "end": 320, "id": 53}, {"text": ".", "start": 320, "end": 321, "id": 54}, {"text": "OD", "start": 322, "end": 324, "id": 55}, {"text": "represents", "start": 325, "end": 335, "id": 56}, {"text": "the", "start": 336, "end": 339, "id": 57}, {"text": "right", "start": 340, "end": 345, "id": 58}, {"text": "eye", "start": 346, "end": 349, "id": 59}, {"text": ";", "start": 349, "end": 350, "id": 60}, {"text": "OS", "start": 351, "end": 353, "id": 61}, {"text": "represents", "start": 354, "end": 364, "id": 62}, {"text": "the", "start": 365, "end": 368, "id": 63}, {"text": "left", "start": 369, "end": 373, "id": 64}, {"text": "eye", "start": 374, "end": 377, "id": 65}, {"text": ".", "start": 377, "end": 378, "id": 66}]}
{"pdf_hash": "9d9f6d541d416e02d3a2805827b197b7994947c0", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Images from a 26-year-old female with type D femoral trochlear dysplasia. (A-D) Continuous sectional magnetic resonance images from the same patient (cross-sectional fat-suppressed fast spin-echo T2 weighted image sequence). (E-H) Computed tomography plain scan cross-sectional images with corresponding femoral trochlear joint facet bone morphologies. 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{"pdf_hash": "3586499f11363b670a799a3f3eb82efccdfcb9ee", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Figure 1 Different views of a 3-dimensional MRI reconstruction of the whole fragile X mouse brain (a\u2013c) and the cerebellum (d).", "width": 654, "height": 1278, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26]}, "subfigures": [{"id": "25f9810b-2160-458b-86cb-effb8cf11f77", "label": "a", "points": [[73.1, 3.1], [73.1, 296.4], [633.8, 296.4], [633.8, 3.1]], "color": "cyan"}, {"id": "b95c912f-faf3-4c74-9152-f1efda0ba904", "label": "a", "points": [[73.1, 300.6], [73.1, 580.4], [630.7, 580.4], [630.7, 300.6]], "color": "magenta"}, {"id": "1232967b-43a6-4843-9bce-5ddac5a73493", "label": "a", "points": [[71, 584.6], [71, 945.3], [635.9, 945.3], [635.9, 584.6]], "color": "springgreen"}, {"id": "85fccfbd-85ef-4cfa-b4ad-dff56f44e9e4", "label": "b", "points": [[75.4, 948.5], [75.4, 1248.1], [637.5, 1248.1], [637.5, 948.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Different", "start": 9, "end": 18, "id": 2}, {"text": "views", "start": 19, "end": 24, "id": 3}, {"text": "of", "start": 25, "end": 27, "id": 4}, {"text": "a", "start": 28, "end": 29, "id": 5}, {"text": "3-dimensional", "start": 30, "end": 43, "id": 6}, {"text": "MRI", "start": 44, "end": 47, "id": 7}, {"text": "reconstruction", "start": 48, "end": 62, "id": 8}, {"text": "of", "start": 63, "end": 65, "id": 9}, {"text": "the", "start": 66, "end": 69, "id": 10}, {"text": "whole", "start": 70, "end": 75, "id": 11}, {"text": "fragile", "start": 76, "end": 83, "id": 12}, {"text": "X", "start": 84, "end": 85, "id": 13}, {"text": "mouse", "start": 86, "end": 91, "id": 14}, {"text": "brain", "start": 92, "end": 97, "id": 15}, {"text": "(", "start": 98, "end": 99, "id": 16}, {"text": "a", "start": 99, "end": 100, "id": 17}, {"text": "\u2013", "start": 100, "end": 101, "id": 18}, {"text": "c", "start": 101, "end": 102, "id": 19}, {"text": ")", "start": 102, "end": 103, "id": 20}, {"text": "and", "start": 104, "end": 107, "id": 21}, {"text": "the", "start": 108, "end": 111, "id": 22}, {"text": "cerebellum", "start": 112, "end": 122, "id": 23}, {"text": "(", "start": 123, "end": 124, "id": 24}, {"text": "d", "start": 124, "end": 125, "id": 25}, {"text": ")", "start": 125, "end": 126, "id": 26}, {"text": ".", "start": 126, "end": 127, "id": 27}]}
{"pdf_hash": "192576abc3c2e3a84b46fdac3dba56c0375c6522", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Fig. 6. Case 2. Preoperative radiographs. Both condylar fragments were displaced to the medio-inferior position and overlapped with ramus. A, B. Panoramic view (arrows). C, D. Axial view of computed tomography. Il-Kyu Kim et al: Intracorporeal reduction of condylar fracture using both pedicled condylar and seperated ramal fragments after vertical ramal osteotomy. J Korean Assoc Oral Maxillofac Surg 2017", "width": 1006, "height": 508, "subcaptions": {"a": [35, 36, 37, 38, 39, 40, 41, 42, 43]}, "subfigures": [{"id": "2adb9535-a7a5-40ae-af9c-917b4db593b8", "label": "a", "points": [[0, 1.6], [0, 505.4], [265.4, 505.4], [265.4, 1.6]], "color": "yellow"}, {"id": "290f360d-d894-486a-96e4-aeef1e252943", "label": "a", "points": [[274.9, 505.4], [274.9, 4.8], [534, 4.8], [534, 505.4]], "color": "cyan"}, {"id": "3c8a4dcf-f218-4404-a989-20614eb47588", "label": "b", "points": [[761.3, 503.8], [761.3, 4.8], [977.4, 4.8], [977.4, 503.8]], "color": "springgreen"}, {"id": "3cc73d34-72ba-42d8-860b-b04266980d5b", "label": "b", "points": [[541.9, 6.4], [541.9, 503.8], [758.1, 503.8], [758.1, 6.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "6", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Case", "start": 8, "end": 12, "id": 4}, {"text": "2", "start": 13, "end": 14, "id": 5}, {"text": ".", "start": 14, "end": 15, "id": 6}, {"text": "Preoperative", "start": 16, "end": 28, "id": 7}, {"text": "radiographs", "start": 29, "end": 40, "id": 8}, {"text": ".", "start": 40, "end": 41, "id": 9}, {"text": "Both", "start": 42, "end": 46, "id": 10}, {"text": "condylar", "start": 47, "end": 55, "id": 11}, {"text": "fragments", "start": 56, "end": 65, "id": 12}, {"text": "were", "start": 66, "end": 70, "id": 13}, {"text": "displaced", "start": 71, "end": 80, "id": 14}, {"text": "to", "start": 81, "end": 83, "id": 15}, {"text": "the", "start": 84, "end": 87, "id": 16}, {"text": "medio", "start": 88, "end": 93, "id": 17}, {"text": "-", "start": 93, "end": 94, "id": 18}, {"text": "inferior", "start": 94, "end": 102, "id": 19}, {"text": "position", "start": 103, "end": 111, "id": 20}, {"text": "and", "start": 112, "end": 115, "id": 21}, {"text": "overlapped", "start": 116, "end": 126, "id": 22}, {"text": "with", "start": 127, "end": 131, "id": 23}, {"text": "ramus", "start": 132, "end": 137, "id": 24}, {"text": ".", "start": 137, "end": 138, "id": 25}, {"text": "A", "start": 139, "end": 140, "id": 26}, {"text": ",", "start": 140, "end": 141, "id": 27}, {"text": "B.", "start": 142, "end": 144, "id": 28}, {"text": "Panoramic", "start": 145, "end": 154, "id": 29}, {"text": "view", "start": 155, "end": 159, "id": 30}, {"text": "(", "start": 160, "end": 161, "id": 31}, {"text": "arrows", "start": 161, "end": 167, "id": 32}, {"text": ")", "start": 167, "end": 168, "id": 33}, {"text": ".", "start": 168, "end": 169, "id": 34}, {"text": "C", "start": 170, "end": 171, "id": 35}, {"text": ",", "start": 171, "end": 172, "id": 36}, {"text": "D.", "start": 173, "end": 175, "id": 37}, {"text": "Axial", "start": 176, "end": 181, "id": 38}, {"text": "view", "start": 182, "end": 186, "id": 39}, {"text": "of", "start": 187, "end": 189, "id": 40}, {"text": "computed", "start": 190, "end": 198, "id": 41}, {"text": "tomography", "start": 199, "end": 209, "id": 42}, {"text": ".", "start": 209, "end": 210, "id": 43}, {"text": "Il", "start": 211, "end": 213, "id": 44}, {"text": "-", "start": 213, "end": 214, "id": 45}, {"text": "Kyu", "start": 214, "end": 217, "id": 46}, {"text": "Kim", "start": 218, "end": 221, "id": 47}, {"text": "et", "start": 222, "end": 224, "id": 48}, {"text": "al", "start": 225, "end": 227, "id": 49}, {"text": ":", "start": 227, "end": 228, "id": 50}, {"text": "Intracorporeal", "start": 229, "end": 243, "id": 51}, {"text": "reduction", "start": 244, "end": 253, "id": 52}, {"text": "of", "start": 254, "end": 256, "id": 53}, {"text": "condylar", "start": 257, "end": 265, "id": 54}, {"text": "fracture", "start": 266, "end": 274, "id": 55}, {"text": "using", "start": 275, "end": 280, "id": 56}, {"text": "both", "start": 281, "end": 285, "id": 57}, {"text": "pedicled", "start": 286, "end": 294, "id": 58}, {"text": "condylar", "start": 295, "end": 303, "id": 59}, {"text": "and", "start": 304, "end": 307, "id": 60}, {"text": "seperated", "start": 308, "end": 317, "id": 61}, {"text": "ramal", "start": 318, "end": 323, "id": 62}, {"text": "fragments", "start": 324, "end": 333, "id": 63}, {"text": "after", "start": 334, "end": 339, "id": 64}, {"text": "vertical", "start": 340, "end": 348, "id": 65}, {"text": "ramal", "start": 349, "end": 354, "id": 66}, {"text": "osteotomy", "start": 355, "end": 364, "id": 67}, {"text": ".", "start": 364, "end": 365, "id": 68}, {"text": "J", "start": 366, "end": 367, "id": 69}, {"text": "Korean", "start": 368, "end": 374, "id": 70}, {"text": "Assoc", "start": 375, "end": 380, "id": 71}, {"text": "Oral", "start": 381, "end": 385, "id": 72}, {"text": "Maxillofac", "start": 386, "end": 396, "id": 73}, {"text": "Surg", "start": 397, "end": 401, "id": 74}, {"text": "2017", "start": 402, "end": 406, "id": 75}]}
{"pdf_hash": "6182c7e53f5f4932151da9b454fda22438465cca", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. (Left) in patient CEUS-006, grayscale conventional ultrasound image demonstrating moderate hydronephrosis of the left kidney. (Right) contrast-enhanced ultrasound image taken at the same time and in the same plane as the grayscale image. Arrows highlight areas of parenchymal thinning and demonstrate the collecting system to apparently extend to the renal capsule with no intervening parenchyma between the surrounding soft tissue and collecting system.", "width": 682, "height": 386, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75]}, "subfigures": [{"id": "a8dd47b9-ee6f-47ef-818a-8128d675d5dc", "label": "a", "points": [[12, 5.7], [12, 368.9], [340.7, 368.9], [340.7, 5.7]], "color": "yellow"}, {"id": "16f1b63e-9238-4ac6-aef5-ab1e63caab15", "label": "b", "points": [[348.2, 4.7], [348.2, 351.6], [672.5, 351.6], [672.5, 4.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", 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{"pdf_hash": "20e3c59bee338f512419d4a1b0c5a74a5d474408", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3 (a) Axial computed tomography and (b) magnetic resonance imaging showing a foreign body in the anterior spinal canal of L5/S1 (arrows), whereas (c) sagittal computed tomography showing a foreign body in the posterior spinal canal.", "width": 652, "height": 934, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "1292cdf2-695e-46d7-8362-230e36338ce9", "label": "a", "points": [[1.6, 1.9], [1.6, 387.1], [325, 387.1], [325, 1.9]], "color": "yellow"}, {"id": "bd392aea-b7bf-4e17-9db2-80a60eeb444b", "label": "b", "points": [[332.2, 0.9], [332.2, 389.2], [648.4, 389.2], [648.4, 0.9]], "color": "cyan"}, {"id": "43e4c259-aaa0-44a6-91e2-361658d3e2a9", "label": "c", "points": [[4.7, 394.3], [4.7, 903.1], [645.3, 903.1], [645.3, 394.3]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Axial", "start": 13, "end": 18, "id": 5}, {"text": "computed", "start": 19, "end": 27, "id": 6}, {"text": "tomography", "start": 28, "end": 38, "id": 7}, {"text": "and", "start": 39, "end": 42, "id": 8}, {"text": "(", "start": 43, "end": 44, "id": 9}, {"text": "b", "start": 44, "end": 45, "id": 10}, {"text": ")", "start": 45, "end": 46, "id": 11}, {"text": "magnetic", "start": 47, "end": 55, "id": 12}, {"text": "resonance", "start": 56, "end": 65, "id": 13}, {"text": "imaging", "start": 66, "end": 73, "id": 14}, {"text": "showing", "start": 74, "end": 81, "id": 15}, {"text": "a", "start": 82, "end": 83, "id": 16}, {"text": "foreign", "start": 84, "end": 91, "id": 17}, {"text": "body", "start": 92, "end": 96, "id": 18}, {"text": "in", "start": 97, "end": 99, "id": 19}, {"text": "the", "start": 100, "end": 103, "id": 20}, {"text": "anterior", "start": 104, "end": 112, "id": 21}, {"text": "spinal", "start": 113, "end": 119, "id": 22}, {"text": "canal", "start": 120, "end": 125, "id": 23}, {"text": "of", "start": 126, "end": 128, "id": 24}, {"text": "L5", "start": 129, "end": 131, "id": 25}, {"text": "/", "start": 131, "end": 132, "id": 26}, {"text": "S1", "start": 132, "end": 134, "id": 27}, {"text": "(", "start": 135, "end": 136, "id": 28}, {"text": "arrows", "start": 136, "end": 142, "id": 29}, {"text": ")", "start": 142, "end": 143, "id": 30}, {"text": ",", "start": 143, "end": 144, "id": 31}, {"text": "whereas", "start": 145, "end": 152, "id": 32}, {"text": "(", "start": 153, "end": 154, "id": 33}, {"text": "c", "start": 154, "end": 155, "id": 34}, {"text": ")", "start": 155, "end": 156, "id": 35}, {"text": "sagittal", "start": 157, "end": 165, "id": 36}, {"text": "computed", "start": 166, "end": 174, "id": 37}, {"text": "tomography", "start": 175, "end": 185, "id": 38}, {"text": "showing", "start": 186, "end": 193, "id": 39}, {"text": "a", "start": 194, "end": 195, "id": 40}, {"text": "foreign", "start": 196, "end": 203, "id": 41}, {"text": "body", "start": 204, "end": 208, "id": 42}, {"text": "in", "start": 209, "end": 211, "id": 43}, {"text": "the", "start": 212, "end": 215, "id": 44}, {"text": "posterior", "start": 216, "end": 225, "id": 45}, {"text": "spinal", "start": 226, "end": 232, "id": 46}, {"text": "canal", "start": 233, "end": 238, "id": 47}, {"text": ".", "start": 238, "end": 239, "id": 48}]}
{"pdf_hash": "f3241622853191f2591f0921f0f1cc9794b73cc1", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. 64-year-old female for initial staging of gastric cancer. The PET-MRI transaxial fusion image shows intense hypermetabolic activity in the gastric cancer with SUV 29.2 and a hypermetabolic enlarged gastrohepatic lymph node (top left). T1 radial vibe transaxial image with fat suppression shows the gastric cancer to be of low to isointense signal and the metastatic lesion to be hyperintense (bottom left). T2 haste transaxial image shows a hyperintense liver lesion that was not active on the PET images which is consistent with a hemangioma (top right). 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{"pdf_hash": "3e29d896a5563c2d2fc8ecae871c0b13864be8d2", "fig_key": "Figure10", "fig_uri": "8-Figure10-1.png", "text": "Fig. 10. Horner syndrome after RF ablation of left thyroid nodule. On transverse (A) and longitudinal (B) ultrasonography, middle cervical sympathetic ganglion (arrowheads) are seen abutting lateral margin of ablated thyroid nodule. Horner syndrome was developed immediately after RF ablation in this patient. RF = radiofrequency", "width": 1210, "height": 454, "subcaptions": {"a": [15, 16, 17, 18], "b": [20, 21, 22, 23]}, "subfigures": [{"id": "5c661366-357e-4bca-894c-1fad068a053c", "label": "a", "points": [[36.6, 2.5], [36.6, 402.1], [610.1, 402.1], [610.1, 2.5]], "color": "yellow"}, {"id": "7eb1dea2-974b-4421-b758-dcc918065bb6", "label": "b", "points": [[629.2, 0.6], [629.2, 407.8], [1206.5, 407.8], [1206.5, 0.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "10", "start": 5, "end": 7, "id": 2}, {"text": ".", "start": 7, "end": 8, "id": 3}, {"text": "Horner", "start": 9, "end": 15, "id": 4}, {"text": "syndrome", "start": 16, "end": 24, "id": 5}, {"text": "after", "start": 25, "end": 30, "id": 6}, {"text": "RF", "start": 31, "end": 33, "id": 7}, {"text": "ablation", "start": 34, "end": 42, "id": 8}, {"text": "of", "start": 43, "end": 45, "id": 9}, {"text": "left", "start": 46, "end": 50, "id": 10}, {"text": "thyroid", "start": 51, "end": 58, "id": 11}, {"text": "nodule", "start": 59, "end": 65, "id": 12}, {"text": ".", "start": 65, "end": 66, "id": 13}, {"text": "On", "start": 67, "end": 69, "id": 14}, {"text": "transverse", "start": 70, "end": 80, "id": 15}, {"text": "(", "start": 81, "end": 82, "id": 16}, {"text": "A", "start": 82, "end": 83, "id": 17}, {"text": ")", "start": 83, "end": 84, "id": 18}, {"text": "and", "start": 85, "end": 88, "id": 19}, {"text": "longitudinal", "start": 89, "end": 101, "id": 20}, {"text": "(", "start": 102, "end": 103, "id": 21}, {"text": "B", "start": 103, "end": 104, "id": 22}, {"text": ")", "start": 104, "end": 105, "id": 23}, {"text": "ultrasonography", "start": 106, "end": 121, "id": 24}, {"text": ",", "start": 121, "end": 122, "id": 25}, {"text": "middle", "start": 123, "end": 129, "id": 26}, {"text": "cervical", "start": 130, "end": 138, "id": 27}, {"text": "sympathetic", "start": 139, "end": 150, "id": 28}, {"text": "ganglion", "start": 151, "end": 159, "id": 29}, {"text": "(", "start": 160, "end": 161, "id": 30}, {"text": "arrowheads", "start": 161, "end": 171, "id": 31}, {"text": ")", "start": 171, "end": 172, "id": 32}, {"text": "are", "start": 173, "end": 176, "id": 33}, {"text": "seen", "start": 177, "end": 181, "id": 34}, {"text": "abutting", "start": 182, "end": 190, "id": 35}, {"text": "lateral", "start": 191, "end": 198, "id": 36}, {"text": "margin", "start": 199, "end": 205, "id": 37}, {"text": "of", "start": 206, "end": 208, "id": 38}, {"text": "ablated", "start": 209, "end": 216, "id": 39}, {"text": "thyroid", "start": 217, "end": 224, "id": 40}, {"text": "nodule", "start": 225, "end": 231, "id": 41}, {"text": ".", "start": 231, "end": 232, "id": 42}, {"text": "Horner", "start": 233, "end": 239, "id": 43}, {"text": "syndrome", "start": 240, "end": 248, "id": 44}, {"text": "was", "start": 249, "end": 252, "id": 45}, {"text": "developed", "start": 253, "end": 262, "id": 46}, {"text": "immediately", "start": 263, "end": 274, "id": 47}, {"text": "after", "start": 275, "end": 280, "id": 48}, {"text": "RF", "start": 281, "end": 283, "id": 49}, {"text": "ablation", "start": 284, "end": 292, "id": 50}, {"text": "in", "start": 293, "end": 295, "id": 51}, {"text": "this", "start": 296, "end": 300, "id": 52}, {"text": "patient", "start": 301, "end": 308, "id": 53}, {"text": ".", "start": 308, "end": 309, "id": 54}, {"text": "RF", "start": 310, "end": 312, "id": 55}, {"text": "=", "start": 313, "end": 314, "id": 56}, {"text": "radiofrequency", "start": 315, "end": 329, "id": 57}]}
{"pdf_hash": "d4dfefd4371c19c86c540a2597078a889882423e", "fig_key": "Figure5", "fig_uri": "3-Figure5-1.png", "text": "Figure 5. Left panel: Sagittal view. Right panel: Horizontal view. Hypoperfusion was found in the frontal lobe (dotted circle).", "width": 1010, "height": 478, "subcaptions": {"a": [3, 4, 5, 6, 7, 8], "b": [9, 10, 11, 12, 13, 14]}, "subfigures": [{"id": "75ae7c71-2418-4e55-be06-94e832a5f5f4", "label": "a", "points": [[38.4, 1.3], [38.4, 443.3], [584, 443.3], [584, 1.3]], "color": "yellow"}, {"id": "82f8d8f0-d5ce-4e67-8fa9-056a39d57dff", "label": "b", "points": [[593.6, 1.3], [593.6, 443.3], [981.3, 443.3], [981.3, 1.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Left", "start": 10, "end": 14, "id": 3}, {"text": "panel", "start": 15, "end": 20, "id": 4}, {"text": ":", "start": 20, "end": 21, "id": 5}, {"text": "Sagittal", "start": 22, "end": 30, "id": 6}, {"text": "view", "start": 31, "end": 35, "id": 7}, {"text": ".", "start": 35, "end": 36, "id": 8}, {"text": "Right", "start": 37, "end": 42, "id": 9}, {"text": "panel", "start": 43, "end": 48, "id": 10}, {"text": ":", "start": 48, "end": 49, "id": 11}, {"text": "Horizontal", "start": 50, "end": 60, "id": 12}, {"text": "view", "start": 61, "end": 65, "id": 13}, {"text": ".", "start": 65, "end": 66, "id": 14}, {"text": "Hypoperfusion", "start": 67, "end": 80, "id": 15}, {"text": "was", "start": 81, "end": 84, "id": 16}, {"text": "found", "start": 85, "end": 90, "id": 17}, {"text": "in", "start": 91, "end": 93, "id": 18}, {"text": "the", "start": 94, "end": 97, "id": 19}, {"text": "frontal", "start": 98, "end": 105, "id": 20}, {"text": "lobe", "start": 106, "end": 110, "id": 21}, {"text": "(", "start": 111, "end": 112, "id": 22}, {"text": "dotted", "start": 112, "end": 118, "id": 23}, {"text": "circle", "start": 119, "end": 125, "id": 24}, {"text": ")", "start": 125, "end": 126, "id": 25}, {"text": ".", "start": 126, "end": 127, "id": 26}]}
{"pdf_hash": "8108cacad7574b2c780666bcd552d5bd729dee07", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Computed tomography: A, coronal image demonstrating a large superior semicircular canal dehiscence (arrow); B, sagittal image showing calcification of the anterior mallear ligament (arrow).", "width": 962, "height": 448, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "a45b703e-2ca3-48ce-a7e7-6415aed26f38", "label": "a", "points": [[30.4, 0], [30.4, 416.4], [498.5, 416.4], [498.5, 0]], "color": "yellow"}, {"id": "3424e54f-f393-4279-8e63-73a9c387dae4", "label": "b", "points": [[509.1, 417.9], [509.1, 3], [931.6, 3], [931.6, 417.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomography", "start": 19, "end": 29, "id": 4}, {"text": ":", "start": 29, "end": 30, "id": 5}, {"text": "A", "start": 31, "end": 32, "id": 6}, {"text": ",", "start": 32, "end": 33, "id": 7}, {"text": "coronal", "start": 34, "end": 41, "id": 8}, {"text": "image", "start": 42, "end": 47, "id": 9}, {"text": "demonstrating", "start": 48, "end": 61, "id": 10}, {"text": "a", "start": 62, "end": 63, "id": 11}, {"text": "large", "start": 64, "end": 69, "id": 12}, {"text": "superior", "start": 70, "end": 78, "id": 13}, {"text": "semicircular", "start": 79, "end": 91, "id": 14}, {"text": "canal", "start": 92, "end": 97, "id": 15}, {"text": "dehiscence", "start": 98, "end": 108, "id": 16}, {"text": "(", "start": 109, "end": 110, "id": 17}, {"text": "arrow", "start": 110, "end": 115, "id": 18}, {"text": ")", "start": 115, "end": 116, "id": 19}, {"text": ";", "start": 116, "end": 117, "id": 20}, {"text": "B", "start": 118, "end": 119, "id": 21}, {"text": ",", "start": 119, "end": 120, "id": 22}, {"text": "sagittal", "start": 121, "end": 129, "id": 23}, {"text": "image", "start": 130, "end": 135, "id": 24}, {"text": "showing", "start": 136, "end": 143, "id": 25}, {"text": "calcification", "start": 144, "end": 157, "id": 26}, {"text": "of", "start": 158, "end": 160, "id": 27}, {"text": "the", "start": 161, "end": 164, "id": 28}, {"text": "anterior", "start": 165, "end": 173, "id": 29}, {"text": "mallear", "start": 174, "end": 181, "id": 30}, {"text": "ligament", "start": 182, "end": 190, "id": 31}, {"text": "(", "start": 191, "end": 192, "id": 32}, {"text": "arrow", "start": 192, "end": 197, "id": 33}, {"text": ")", "start": 197, "end": 198, "id": 34}, {"text": ".", "start": 198, "end": 199, "id": 35}]}
{"pdf_hash": "8e31d2879da7fa35e63d7029c8900f4aa7b103e6", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5. Imaging of a fixed mouse ear embedded in agar. Total (a) A color photograph of the ear; (b) MAP of the 3D reconstructed optoacoustic image of mouse ear. Scale bar: 1 mm. 3D rendering can be found in Media 2.", "width": 558, "height": 354, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "94896843-804f-4a77-9f81-b6a5ad5b1851", "label": "a", "points": [[32, 2.8], [32, 316.8], [267, 316.8], [267, 2.8]], "color": "yellow"}, {"id": "f0f23d47-a398-41e3-a888-b688eadd452c", "label": "b", "points": [[280, 2.8], [280, 316.8], [527, 316.8], [527, 2.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Imaging", "start": 8, "end": 15, "id": 4}, {"text": "of", "start": 16, "end": 18, "id": 5}, {"text": "a", "start": 19, "end": 20, "id": 6}, {"text": "fixed", "start": 21, "end": 26, "id": 7}, {"text": "mouse", "start": 27, "end": 32, "id": 8}, {"text": "ear", "start": 33, "end": 36, "id": 9}, {"text": "embedded", "start": 37, "end": 45, "id": 10}, {"text": "in", "start": 46, "end": 48, "id": 11}, {"text": "agar", "start": 49, "end": 53, "id": 12}, {"text": ".", "start": 53, "end": 54, "id": 13}, {"text": "Total", "start": 55, "end": 60, "id": 14}, {"text": "(", "start": 61, "end": 62, "id": 15}, {"text": "a", "start": 62, "end": 63, "id": 16}, {"text": ")", "start": 63, "end": 64, "id": 17}, {"text": "A", "start": 65, "end": 66, "id": 18}, {"text": "color", "start": 67, "end": 72, "id": 19}, {"text": "photograph", "start": 73, "end": 83, "id": 20}, {"text": "of", "start": 84, "end": 86, "id": 21}, {"text": "the", "start": 87, "end": 90, "id": 22}, {"text": "ear", "start": 91, "end": 94, "id": 23}, {"text": ";", "start": 94, "end": 95, "id": 24}, {"text": "(", "start": 96, "end": 97, "id": 25}, {"text": "b", "start": 97, "end": 98, "id": 26}, {"text": ")", "start": 98, "end": 99, "id": 27}, {"text": "MAP", "start": 100, "end": 103, "id": 28}, {"text": "of", "start": 104, "end": 106, "id": 29}, {"text": "the", "start": 107, "end": 110, "id": 30}, {"text": "3D", "start": 111, "end": 113, "id": 31}, {"text": "reconstructed", "start": 114, "end": 127, "id": 32}, {"text": "optoacoustic", "start": 128, "end": 140, "id": 33}, {"text": "image", "start": 141, "end": 146, "id": 34}, {"text": "of", "start": 147, "end": 149, "id": 35}, {"text": "mouse", "start": 150, "end": 155, "id": 36}, {"text": "ear", "start": 156, "end": 159, "id": 37}, {"text": ".", "start": 159, "end": 160, "id": 38}, {"text": "Scale", "start": 161, "end": 166, "id": 39}, {"text": "bar", "start": 167, "end": 170, "id": 40}, {"text": ":", "start": 170, "end": 171, "id": 41}, {"text": "1", "start": 172, "end": 173, "id": 42}, {"text": "mm", "start": 174, "end": 176, "id": 43}, {"text": ".", "start": 176, "end": 177, "id": 44}, {"text": "3D", "start": 178, "end": 180, "id": 45}, {"text": "rendering", "start": 181, "end": 190, "id": 46}, {"text": "can", "start": 191, "end": 194, "id": 47}, {"text": "be", "start": 195, "end": 197, "id": 48}, {"text": "found", "start": 198, "end": 203, "id": 49}, {"text": "in", "start": 204, "end": 206, "id": 50}, {"text": "Media", "start": 207, "end": 212, "id": 51}, {"text": "2", "start": 213, "end": 214, "id": 52}, {"text": ".", "start": 214, "end": 215, "id": 53}]}
{"pdf_hash": "7f7e93aebe934c00394007bf9acd79b7b37d40c8", "fig_key": "Figure13", "fig_uri": "11-Figure13-1.png", "text": "Fig. 13 PASL images acquired with ss-FSE readout: a proton density; b control image; c labelling d perfusion-weighted imaging normalized to proton density (Li et al. [50])", "width": 1354, "height": 176, "subcaptions": {"a": [12, 13, 14, 15], "b": [16, 17, 18, 19], "c": [20, 21], "d": [22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "eb9fe4f1-c8a1-4048-a6d6-90caea6603a7", "label": "a", "points": [[5.4, 6.1], [5.4, 168.7], [324.2, 168.7], [324.2, 6.1]], "color": "yellow"}, {"id": "7f5bea3e-2124-47b3-bdf3-cfa378ad3679", "label": "b", "points": [[341.3, 3.9], [341.3, 170.8], [636.6, 170.8], [636.6, 3.9]], "color": "cyan"}, {"id": "e8e7d571-f6d6-4216-8952-5c4642705898", "label": "c", "points": [[655.8, 8.2], [655.8, 168.7], [966, 168.7], [966, 8.2]], "color": "magenta"}, {"id": "1e97b1ca-b6b3-4f6f-b138-e51c3bd8fff0", "label": "d", "points": [[983.1, -0.4], [983.1, 168.7], [1314.8, 168.7], [1314.8, -0.4]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "13", "start": 5, "end": 7, "id": 2}, {"text": "PASL", "start": 8, "end": 12, "id": 3}, {"text": "images", "start": 13, "end": 19, "id": 4}, {"text": "acquired", "start": 20, "end": 28, "id": 5}, {"text": "with", "start": 29, "end": 33, "id": 6}, {"text": "ss", "start": 34, "end": 36, "id": 7}, {"text": "-", "start": 36, "end": 37, "id": 8}, {"text": "FSE", "start": 37, "end": 40, "id": 9}, {"text": "readout", "start": 41, "end": 48, "id": 10}, {"text": ":", "start": 48, "end": 49, "id": 11}, {"text": "a", "start": 50, "end": 51, "id": 12}, {"text": "proton", "start": 52, "end": 58, "id": 13}, {"text": "density", "start": 59, "end": 66, "id": 14}, {"text": ";", "start": 66, "end": 67, "id": 15}, {"text": "b", "start": 68, "end": 69, "id": 16}, {"text": "control", "start": 70, "end": 77, "id": 17}, {"text": "image", "start": 78, "end": 83, "id": 18}, {"text": ";", "start": 83, "end": 84, "id": 19}, {"text": "c", "start": 85, "end": 86, "id": 20}, {"text": "labelling", "start": 87, "end": 96, "id": 21}, {"text": "d", "start": 97, "end": 98, "id": 22}, {"text": "perfusion", "start": 99, "end": 108, "id": 23}, {"text": "-", "start": 108, "end": 109, "id": 24}, {"text": "weighted", "start": 109, "end": 117, "id": 25}, {"text": "imaging", "start": 118, "end": 125, "id": 26}, {"text": "normalized", "start": 126, "end": 136, "id": 27}, {"text": "to", "start": 137, "end": 139, "id": 28}, {"text": "proton", "start": 140, "end": 146, "id": 29}, {"text": "density", "start": 147, "end": 154, "id": 30}, {"text": "(", "start": 155, "end": 156, "id": 31}, {"text": "Li", "start": 156, "end": 158, "id": 32}, {"text": "et", "start": 159, "end": 161, "id": 33}, {"text": "al", "start": 162, "end": 164, "id": 34}, {"text": ".", "start": 164, "end": 165, "id": 35}, {"text": "[", "start": 166, "end": 167, "id": 36}, {"text": "50", "start": 167, "end": 169, "id": 37}, {"text": "]", "start": 169, "end": 170, "id": 38}, {"text": ")", "start": 170, "end": 171, "id": 39}]}
{"pdf_hash": "5485f40319b5f3b8123f135155cf8da921d1e728", "fig_key": "Figure13", "fig_uri": "11-Figure13-1.png", "text": "Figure 13: Mixed subtype adenocarcinoma, progression of GGO to a nodule with mixed solid component and GGO. (a) Magnified 1-mm CT section shows a discrete GGO (arrows). (b) Follow-up CT scan obtained 1 year later shows clear progression of the disease, with the development of a central solid component, although there is no appreciable enlargement of the lesion (arrows).", "width": 946, "height": 590, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75]}, "subfigures": [{"id": "5f6213c3-8824-4d88-b382-15c31c41141b", "label": "a", "points": [[35.9, 43.3], [35.9, 517.1], [478.2, 517.1], [478.2, 43.3]], "color": "yellow"}, {"id": "cde14e4f-3c86-4d4c-8bef-ea3b40298b08", "label": "b", "points": [[497.7, 511.1], [497.7, 38.9], [941.5, 38.9], [941.5, 511.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "13", "start": 7, "end": 9, "id": 1}, {"text": ":", "start": 9, "end": 10, "id": 2}, {"text": "Mixed", "start": 11, "end": 16, "id": 3}, {"text": "subtype", "start": 17, "end": 24, "id": 4}, {"text": "adenocarcinoma", "start": 25, "end": 39, "id": 5}, {"text": ",", "start": 39, "end": 40, "id": 6}, {"text": "progression", "start": 41, "end": 52, "id": 7}, {"text": "of", "start": 53, "end": 55, "id": 8}, {"text": "GGO", "start": 56, "end": 59, "id": 9}, {"text": "to", "start": 60, "end": 62, "id": 10}, {"text": "a", "start": 63, "end": 64, "id": 11}, {"text": "nodule", "start": 65, "end": 71, "id": 12}, {"text": "with", "start": 72, "end": 76, "id": 13}, {"text": "mixed", "start": 77, "end": 82, "id": 14}, {"text": "solid", "start": 83, "end": 88, "id": 15}, {"text": "component", "start": 89, "end": 98, "id": 16}, {"text": "and", "start": 99, "end": 102, "id": 17}, {"text": "GGO", "start": 103, "end": 106, "id": 18}, {"text": ".", "start": 106, "end": 107, "id": 19}, {"text": "(", "start": 108, "end": 109, "id": 20}, {"text": "a", "start": 109, "end": 110, "id": 21}, {"text": ")", "start": 110, "end": 111, "id": 22}, {"text": "Magnified", "start": 112, "end": 121, "id": 23}, {"text": "1-mm", "start": 122, "end": 126, "id": 24}, {"text": "CT", "start": 127, "end": 129, "id": 25}, {"text": "section", "start": 130, "end": 137, "id": 26}, {"text": "shows", "start": 138, "end": 143, "id": 27}, {"text": "a", "start": 144, "end": 145, "id": 28}, {"text": "discrete", "start": 146, "end": 154, "id": 29}, {"text": "GGO", "start": 155, "end": 158, "id": 30}, {"text": "(", "start": 159, "end": 160, "id": 31}, {"text": "arrows", "start": 160, "end": 166, "id": 32}, {"text": ")", "start": 166, "end": 167, "id": 33}, {"text": ".", "start": 167, "end": 168, "id": 34}, {"text": "(", "start": 169, "end": 170, "id": 35}, {"text": "b", "start": 170, "end": 171, "id": 36}, {"text": ")", "start": 171, "end": 172, "id": 37}, {"text": "Follow", "start": 173, "end": 179, "id": 38}, {"text": "-", "start": 179, "end": 180, "id": 39}, {"text": "up", "start": 180, "end": 182, "id": 40}, {"text": "CT", "start": 183, "end": 185, "id": 41}, {"text": "scan", "start": 186, "end": 190, "id": 42}, {"text": "obtained", "start": 191, "end": 199, "id": 43}, {"text": "1", "start": 200, "end": 201, "id": 44}, {"text": "year", "start": 202, "end": 206, "id": 45}, {"text": "later", "start": 207, "end": 212, "id": 46}, {"text": "shows", "start": 213, "end": 218, "id": 47}, {"text": "clear", "start": 219, "end": 224, "id": 48}, {"text": "progression", "start": 225, "end": 236, "id": 49}, {"text": "of", "start": 237, "end": 239, "id": 50}, {"text": "the", "start": 240, "end": 243, "id": 51}, {"text": "disease", "start": 244, "end": 251, "id": 52}, {"text": ",", "start": 251, "end": 252, "id": 53}, {"text": "with", "start": 253, "end": 257, "id": 54}, {"text": "the", "start": 258, "end": 261, "id": 55}, {"text": "development", "start": 262, "end": 273, "id": 56}, {"text": "of", "start": 274, "end": 276, "id": 57}, {"text": "a", "start": 277, "end": 278, "id": 58}, {"text": "central", "start": 279, "end": 286, "id": 59}, {"text": "solid", "start": 287, "end": 292, "id": 60}, {"text": "component", "start": 293, "end": 302, "id": 61}, {"text": ",", "start": 302, "end": 303, "id": 62}, {"text": "although", "start": 304, "end": 312, "id": 63}, {"text": "there", "start": 313, "end": 318, "id": 64}, {"text": "is", "start": 319, "end": 321, "id": 65}, {"text": "no", "start": 322, "end": 324, "id": 66}, {"text": "appreciable", "start": 325, "end": 336, "id": 67}, {"text": "enlargement", "start": 337, "end": 348, "id": 68}, {"text": "of", "start": 349, "end": 351, "id": 69}, {"text": "the", "start": 352, "end": 355, "id": 70}, {"text": "lesion", "start": 356, "end": 362, "id": 71}, {"text": "(", "start": 363, "end": 364, "id": 72}, {"text": "arrows", "start": 364, "end": 370, "id": 73}, {"text": ")", "start": 370, "end": 371, "id": 74}, {"text": ".", "start": 371, "end": 372, "id": 75}]}
{"pdf_hash": "c6a58fae9c1e4f1919f21ea04be71d11976906f9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Immunohistochemical analysis of B cells in NPMc \u00fe AML. Top, left: bone marrow biopsy (paraffin section) from an NPMc \u00fe AML patient with FAB-M5 morphology (hematoxylin-eosin; \u00c2 800). Top, right: the same case showing the characteristic nuclear and aberrant cytoplasmic expression of NPM (arrow) (APAAP; hematoxylin counterstain; \u00c2 800). Bottom, left: paraffin section from the same case showing the presence of scattered CD20-positive cells (arrow), as expected leukaemic cells are CD20-negative (APAAP; hematoxylin counterstain; \u00c2 800). Bottom, right: double staining for CD20 by immunoperoxidase (brown) and for mutated NPM (NPMm) by the APAAP technique with Sil-A antibody (blue). As expected, leukaemic cells are CD20-negative and show aberrant cytoplasmicrestricted positivity for mutated NPM (blue) (double arrows); in contrast, CD20 cells display surface CD20-positivity (brown), but are negative for Sil-A (single arrow), indicating absence of NPM mutated protein (no counterstaining; \u00c2 800).", "width": 652, "height": 500, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72], "c": [73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109], "d": [110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 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{"pdf_hash": "61771af46acef77fb463198f263efb31bc6d67c0", "fig_key": "Figure8", "fig_uri": "9-Figure8-1.png", "text": "Fig. 8. Gastric intestinal metaplasia. (A) White light imaging shows an irregular depressed lesion, suggesting advanced gastric cancer or mucosa-associated lymphoid tissue lymphoma on the greater curvature. However, (B) linked color imaging shows a purple lesion homogenously spreading in the depressed area, suggesting intestinal metaplasia. (C) Blue laser imaging shows a regular surface pattern with green circle lines corresponding to the marginal crypt epithelium, suggesting intestinal metaplasia. 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{"pdf_hash": "0ea709b79629449c32470ab5a2455108c0d47fe8", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 A 9.6-mm hemorrhagic lesion in the right cerebellar hemisphere. a T2-weighted gradient-echo cranial magnetic resonance image in the axial plane shows low signal intensity in the right cerebellar hemisphere. b Axial T1-weighted sequence shows no abnormally enhancing lesion following administration of intravenous gadolinium", "width": 856, "height": 442, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "f9a8dd5a-d1c5-4b5c-a921-ca2a820375aa", "label": "a", "points": [[39.6, 17.4], [39.6, 406.9], [423.6, 406.9], [423.6, 17.4]], "color": "yellow"}, {"id": "444e4143-9e99-4316-9b1d-8ec2bfe16498", "label": "b", "points": [[435.8, 18.8], [435.8, 408.2], [825.3, 408.2], [825.3, 18.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "9.6-mm", "start": 9, "end": 15, "id": 4}, {"text": "hemorrhagic", "start": 16, "end": 27, "id": 5}, {"text": "lesion", "start": 28, "end": 34, "id": 6}, {"text": "in", "start": 35, "end": 37, "id": 7}, {"text": "the", "start": 38, "end": 41, "id": 8}, {"text": "right", "start": 42, "end": 47, "id": 9}, {"text": "cerebellar", "start": 48, "end": 58, "id": 10}, {"text": "hemisphere", "start": 59, "end": 69, "id": 11}, {"text": ".", "start": 69, "end": 70, "id": 12}, {"text": "a", "start": 71, "end": 72, "id": 13}, {"text": "T2-weighted", "start": 73, "end": 84, "id": 14}, {"text": "gradient", "start": 85, "end": 93, "id": 15}, {"text": "-", "start": 93, "end": 94, "id": 16}, {"text": "echo", "start": 94, "end": 98, "id": 17}, {"text": "cranial", "start": 99, "end": 106, "id": 18}, {"text": "magnetic", "start": 107, "end": 115, "id": 19}, {"text": "resonance", "start": 116, "end": 125, "id": 20}, {"text": "image", "start": 126, "end": 131, "id": 21}, {"text": "in", "start": 132, "end": 134, "id": 22}, {"text": "the", "start": 135, "end": 138, "id": 23}, {"text": "axial", "start": 139, "end": 144, "id": 24}, {"text": "plane", "start": 145, "end": 150, "id": 25}, {"text": "shows", "start": 151, "end": 156, "id": 26}, {"text": "low", "start": 157, "end": 160, "id": 27}, {"text": "signal", "start": 161, "end": 167, "id": 28}, {"text": "intensity", "start": 168, "end": 177, "id": 29}, {"text": "in", "start": 178, "end": 180, "id": 30}, {"text": "the", "start": 181, "end": 184, "id": 31}, {"text": "right", "start": 185, "end": 190, "id": 32}, {"text": "cerebellar", "start": 191, "end": 201, "id": 33}, {"text": "hemisphere", "start": 202, "end": 212, "id": 34}, {"text": ".", "start": 212, "end": 213, "id": 35}, {"text": "b", "start": 214, "end": 215, "id": 36}, {"text": "Axial", "start": 216, "end": 221, "id": 37}, {"text": "T1-weighted", "start": 222, "end": 233, "id": 38}, {"text": "sequence", "start": 234, "end": 242, "id": 39}, {"text": "shows", "start": 243, "end": 248, "id": 40}, {"text": "no", "start": 249, "end": 251, "id": 41}, {"text": "abnormally", "start": 252, "end": 262, "id": 42}, {"text": "enhancing", "start": 263, "end": 272, "id": 43}, {"text": "lesion", "start": 273, "end": 279, "id": 44}, {"text": "following", "start": 280, "end": 289, "id": 45}, {"text": "administration", "start": 290, "end": 304, "id": 46}, {"text": "of", "start": 305, "end": 307, "id": 47}, {"text": "intravenous", "start": 308, "end": 319, "id": 48}, {"text": "gadolinium", "start": 320, "end": 330, "id": 49}]}
{"pdf_hash": "a62ea96aba070de3685c365a119833da108bf1ad", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "FIGURE 1. A, synovial sarcoma of biphasic type (hematoxylin and eosin stain; original magnification, 380). B, synovial sarcoma of monophasic type showing many mitotic figures (arrowheads) (hematoxylin and eosin stain; original magnification, 3100). C, distinct nuclear staining of Ki-67 antigen is detected in many tumor cells, monophasic type (original magnification, 3100).", "width": 632, "height": 1456, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "c": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71]}, "subfigures": [{"id": "b8f69fdc-0986-40b8-aaa0-33de383817e6", "label": "a", "points": [[11, 1.8], [11, 466.8], [627, 466.8], [627, 1.8]], "color": "yellow"}, {"id": "fc5f5864-1774-4ab7-abb6-fd0a8c3ea174", "label": "b", "points": [[10, 479.3], [10, 945.4], [630, 945.4], [630, 479.3]], "color": "cyan"}, {"id": "c438f7dd-0fd7-4a25-866e-52488c6ac97f", "label": "c", "points": [[10, 957.9], [10, 1422.9], [629, 1422.9], [629, 957.9]], "color": "magenta"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "synovial", "start": 13, "end": 21, "id": 5}, {"text": "sarcoma", "start": 22, "end": 29, "id": 6}, {"text": "of", "start": 30, "end": 32, "id": 7}, {"text": "biphasic", "start": 33, "end": 41, "id": 8}, {"text": "type", "start": 42, "end": 46, "id": 9}, {"text": "(", "start": 47, "end": 48, "id": 10}, {"text": "hematoxylin", "start": 48, "end": 59, "id": 11}, {"text": "and", "start": 60, "end": 63, "id": 12}, {"text": "eosin", "start": 64, "end": 69, "id": 13}, {"text": "stain", "start": 70, "end": 75, "id": 14}, {"text": ";", "start": 75, "end": 76, "id": 15}, {"text": "original", "start": 77, "end": 85, "id": 16}, {"text": "magnification", "start": 86, "end": 99, "id": 17}, {"text": ",", "start": 99, "end": 100, "id": 18}, {"text": "380", "start": 101, "end": 104, "id": 19}, {"text": ")", "start": 104, "end": 105, "id": 20}, {"text": ".", "start": 105, "end": 106, "id": 21}, {"text": "B", "start": 107, "end": 108, "id": 22}, {"text": ",", "start": 108, "end": 109, "id": 23}, {"text": "synovial", "start": 110, "end": 118, "id": 24}, {"text": "sarcoma", "start": 119, "end": 126, "id": 25}, {"text": "of", "start": 127, "end": 129, "id": 26}, {"text": "monophasic", "start": 130, "end": 140, "id": 27}, {"text": "type", "start": 141, "end": 145, "id": 28}, {"text": "showing", "start": 146, "end": 153, "id": 29}, {"text": "many", "start": 154, "end": 158, "id": 30}, {"text": "mitotic", "start": 159, "end": 166, "id": 31}, {"text": "figures", "start": 167, "end": 174, "id": 32}, {"text": "(", "start": 175, "end": 176, "id": 33}, {"text": "arrowheads", "start": 176, "end": 186, "id": 34}, {"text": ")", "start": 186, "end": 187, "id": 35}, {"text": "(", "start": 188, "end": 189, "id": 36}, {"text": "hematoxylin", "start": 189, "end": 200, "id": 37}, {"text": "and", "start": 201, "end": 204, "id": 38}, {"text": "eosin", "start": 205, "end": 210, "id": 39}, {"text": "stain", "start": 211, "end": 216, "id": 40}, {"text": ";", "start": 216, "end": 217, "id": 41}, {"text": "original", "start": 218, "end": 226, "id": 42}, {"text": "magnification", "start": 227, "end": 240, "id": 43}, {"text": ",", "start": 240, "end": 241, "id": 44}, {"text": "3100", "start": 242, "end": 246, "id": 45}, {"text": ")", "start": 246, "end": 247, "id": 46}, {"text": ".", "start": 247, "end": 248, "id": 47}, {"text": "C", "start": 249, "end": 250, "id": 48}, {"text": ",", "start": 250, "end": 251, "id": 49}, {"text": "distinct", "start": 252, "end": 260, "id": 50}, {"text": "nuclear", "start": 261, "end": 268, "id": 51}, {"text": "staining", "start": 269, "end": 277, "id": 52}, {"text": "of", "start": 278, "end": 280, "id": 53}, {"text": "Ki-67", "start": 281, "end": 286, "id": 54}, {"text": "antigen", "start": 287, "end": 294, "id": 55}, {"text": "is", "start": 295, "end": 297, "id": 56}, {"text": "detected", "start": 298, "end": 306, "id": 57}, {"text": "in", "start": 307, "end": 309, "id": 58}, {"text": "many", "start": 310, "end": 314, "id": 59}, {"text": "tumor", "start": 315, "end": 320, "id": 60}, {"text": "cells", "start": 321, "end": 326, "id": 61}, {"text": ",", "start": 326, "end": 327, "id": 62}, {"text": "monophasic", "start": 328, "end": 338, "id": 63}, {"text": "type", "start": 339, "end": 343, "id": 64}, {"text": "(", "start": 344, "end": 345, "id": 65}, {"text": "original", "start": 345, "end": 353, "id": 66}, {"text": "magnification", "start": 354, "end": 367, "id": 67}, {"text": ",", "start": 367, "end": 368, "id": 68}, {"text": "3100", "start": 369, "end": 373, "id": 69}, {"text": ")", "start": 373, "end": 374, "id": 70}, {"text": ".", "start": 374, "end": 375, "id": 71}]}
{"pdf_hash": "45d9bc1d7359c7a51f48bc09f1e6e0bf3a06039a", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. A \u2013 52-year-old man, CT showed single vertebral metastasis in the right vertebral sector of T12 (indicated by arrow; B \u2013 39-yearold man, CT showed single bone destruction in the appendix sector of T2, with no penetration into the vertebral body, soft tissue mass encysted the spinous process (indicated by arrow); C \u2013 The same patient CT showed bone destruction in the left appendix sector of T11, where soft tissue mass extended from the appendix sector to the posterior edge of the left vertebra (indicated by arrow); D \u2013 Patient with separate metastases in vertebral body and appendix in L5 (indicated by arrow); soft tissue mass formed at the posterior edge of the left vertebra, a separate metastasis observed at the posterior edge of the left vertebral body", "width": 1296, "height": 896, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 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{"pdf_hash": "390b53b4991c60e6101ada79268621153486a19d", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4. feSEM and TEM of lamin B2-induced intranuclear membrane arrays. FLAG-tagged lamin B2 was expressed by nuclear injection of plasmid DNA. (A) Nuclear envelope of an oocyte overexpressing lamin B2, shown at low magnification. (B) Membrane arrays covered by irregular wavy lamin B2 filaments. (C) A more-ordered package of lamin B2 filaments on a membrane array. Note the more-or-less parallel alignment of B2 filaments. (D) TEM section of an isolated oocyte nucleus expressing lamin B2. (E,F) Immuno-feSEM detection of lamin B2 on membrane arrays using the mAb L7-8C6 that is specific for Xenopus lamin B2 (E) and antibodies against the FLAG epitope (F). 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{"pdf_hash": "56e3c9bfad970423af13890fe04e9f81f0860750", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "FIGURE 1. A 79-year-old man (case 5, SCC, stage 2) with complaints of otorrhea and otalgia for 12 months. HRCT and MRI were done (A-C). Axial HRCT revealed a soft tissue mass and stenosis of right EAC and (A). The lesion is iso-intense on T1WI (B) and hyper-intense on fat suppression T2WI (C). The lesion reaches the bony part of the EAC and involves the inferior wall of the EAC. A 65-year-old woman (case 35, cystic adenocarcinoma, stage 1) with complaints of otalgia and mass in her right ear for 1 month. HRCT and MRI were done (D-F). Axial HRCT (D) shows a focal mass locating at cartilage part of the EAC without bone changes. The lesion shows homogeneous signal intensity on both T1WI (E) and T2WI (F). 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{"pdf_hash": "0fc628cd06ea9b15a64bcd1c64656255ec629729", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig 3. An abnormality detected during screening mammography in a 69-year-old asymptomatic woman. (A) Left craniocaudal magnification and compression views show segmental pleomorphic microcalcifications that correlate with the ultrasound (US)-detected lesion (mammography skin marking). (B) US shows ductal dilatation with internal microcalcification (arrows). (C) Photomicrography of a 13-gauge vacuum-assisted biopsy (original magnification, \u00d740; hematoxylin and eosin [H&E] stain) shows tumor cell infiltration into the stroma; this case was confirmed as an invasive ductal carcinoma (arrows). (D) Only ductal carcinoma in situ (DCIS; 5.6-cm extent) remained in the mastectomy specimen. 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{"pdf_hash": "e74ea13bf15f9fdf86ee06317da7e93e78af6271", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Percentage of facet joint preservation, measured on axial computed tomography images at L4\u2013L5 preoperatively (A) and immediately postoperatively (B). Percentage of facet joint preservation= b/a\u00d7100.", "width": 640, "height": 334, "subcaptions": {"a": [18, 19, 20, 21], "b": [23, 24, 25, 26, 27]}, "subfigures": [{"id": "70a64344-be17-46b7-bf68-5199239c65fe", "label": "a", "points": [[4.2, 1.3], [4.2, 315.8], [308.6, 315.8], [308.6, 1.3]], "color": "yellow"}, {"id": "c9c1d70f-5238-4e6d-ad47-e25c7ce04173", "label": "b", "points": [[320.7, 6.4], [320.7, 313.8], [638.2, 313.8], [638.2, 6.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Percentage", "start": 8, "end": 18, "id": 4}, {"text": "of", "start": 19, "end": 21, "id": 5}, {"text": "facet", "start": 22, "end": 27, "id": 6}, {"text": "joint", "start": 28, "end": 33, "id": 7}, {"text": "preservation", "start": 34, "end": 46, "id": 8}, {"text": ",", "start": 46, "end": 47, "id": 9}, {"text": "measured", "start": 48, "end": 56, "id": 10}, {"text": "on", "start": 57, "end": 59, "id": 11}, {"text": "axial", "start": 60, "end": 65, "id": 12}, {"text": "computed", "start": 66, "end": 74, "id": 13}, {"text": "tomography", "start": 75, "end": 85, "id": 14}, {"text": "images", "start": 86, "end": 92, "id": 15}, {"text": "at", "start": 93, "end": 95, "id": 16}, {"text": "L4\u2013L5", "start": 96, "end": 101, "id": 17}, {"text": "preoperatively", "start": 102, "end": 116, "id": 18}, {"text": "(", "start": 117, "end": 118, "id": 19}, {"text": "A", "start": 118, "end": 119, "id": 20}, {"text": ")", "start": 119, "end": 120, "id": 21}, {"text": "and", "start": 121, "end": 124, "id": 22}, {"text": "immediately", "start": 125, "end": 136, "id": 23}, {"text": "postoperatively", "start": 137, "end": 152, "id": 24}, {"text": "(", "start": 153, "end": 154, "id": 25}, {"text": "B", "start": 154, "end": 155, "id": 26}, {"text": ")", "start": 155, "end": 156, "id": 27}, {"text": ".", "start": 156, "end": 157, "id": 28}, {"text": "Percentage", "start": 158, "end": 168, "id": 29}, {"text": "of", "start": 169, "end": 171, "id": 30}, {"text": "facet", "start": 172, "end": 177, "id": 31}, {"text": "joint", "start": 178, "end": 183, "id": 32}, {"text": "preservation=", "start": 184, "end": 197, "id": 33}, {"text": "b", "start": 198, "end": 199, "id": 34}, {"text": "/", "start": 199, "end": 200, "id": 35}, {"text": "a\u00d7100", "start": 200, "end": 205, "id": 36}, {"text": ".", "start": 205, "end": 206, "id": 37}]}
{"pdf_hash": "7865f97e27403a615b0e8edfb793d2cf0d6d5426", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Typical X-ray photographic image of the patellar movement Left side: before movement, Right side: after movement", "width": 630, "height": 320, "subcaptions": {"a": [14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24]}, "subfigures": [{"id": "edeafe93-66cb-4156-853a-4de27342d554", "label": "a", "points": [[7.5, 11], [7.5, 316], [307.5, 316], [307.5, 11]], "color": "yellow"}, {"id": "1e920723-a43d-484c-a0e1-37c2b0027f31", "label": "b", "points": [[312.5, 316], [312.5, 4], [622.5, 4], [622.5, 316]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Typical", "start": 8, "end": 15, "id": 4}, {"text": "X", "start": 16, "end": 17, "id": 5}, {"text": "-", "start": 17, "end": 18, "id": 6}, {"text": "ray", "start": 18, "end": 21, "id": 7}, {"text": "photographic", "start": 22, "end": 34, "id": 8}, {"text": "image", "start": 35, "end": 40, "id": 9}, {"text": "of", "start": 41, "end": 43, "id": 10}, {"text": "the", "start": 44, "end": 47, "id": 11}, {"text": "patellar", "start": 48, "end": 56, "id": 12}, {"text": "movement", "start": 57, "end": 65, "id": 13}, {"text": "Left", "start": 66, "end": 70, "id": 14}, {"text": "side", "start": 71, "end": 75, "id": 15}, {"text": ":", "start": 75, "end": 76, "id": 16}, {"text": "before", "start": 77, "end": 83, "id": 17}, {"text": "movement", "start": 84, "end": 92, "id": 18}, {"text": ",", "start": 92, "end": 93, "id": 19}, {"text": "Right", "start": 94, "end": 99, "id": 20}, {"text": "side", "start": 100, "end": 104, "id": 21}, {"text": ":", "start": 104, "end": 105, "id": 22}, {"text": "after", "start": 106, "end": 111, "id": 23}, {"text": "movement", "start": 112, "end": 120, "id": 24}]}
{"pdf_hash": "d9630a4181f10f097c2173d7d2baf3f81fa30b85", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Abdominal CT shows the complex congenital umbilical AVM. (A) Umbilical drainage vein (arrow), (B and C) nidus is showed (asterisk), and (D) multiple efferent arteries coming from hypogastric and external iliac. AVM, arteriovenous malformation; CT, computed tomography.", "width": 1144, "height": 836, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "2976e5c1-96af-4e8c-94ba-166a13ef7c02", "label": "a", "points": [[28.1, -0.3], [28.1, 395.5], [568.4, 395.5], [568.4, -0.3]], "color": "yellow"}, {"id": "d66794ad-f8cf-4b0a-889f-a45cc1b2607e", "label": "b", "points": [[1114.2, 391.9], [1114.2, 6.9], [577.5, 6.9], [577.5, 391.9]], "color": "cyan"}, {"id": "02c1ae13-c551-4a39-95d7-ef8b8248f1e0", "label": "b", "points": [[31.7, 406.3], [31.7, 805.7], [550.3, 805.7], [550.3, 406.3]], "color": "magenta"}, {"id": "bf10870a-5d0d-4c9e-a417-74c6063ff7ee", "label": "c", "points": [[570.2, 406.3], [570.2, 802.1], [1110.6, 802.1], [1110.6, 406.3]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Abdominal", "start": 7, "end": 16, "id": 3}, {"text": "CT", "start": 17, "end": 19, "id": 4}, {"text": "shows", "start": 20, "end": 25, "id": 5}, {"text": "the", "start": 26, "end": 29, "id": 6}, {"text": "complex", "start": 30, "end": 37, "id": 7}, {"text": "congenital", "start": 38, "end": 48, "id": 8}, {"text": "umbilical", "start": 49, "end": 58, "id": 9}, {"text": "AVM", "start": 59, "end": 62, "id": 10}, {"text": ".", "start": 62, "end": 63, "id": 11}, {"text": "(", "start": 64, "end": 65, "id": 12}, {"text": "A", "start": 65, "end": 66, "id": 13}, {"text": ")", "start": 66, "end": 67, "id": 14}, {"text": "Umbilical", "start": 68, "end": 77, "id": 15}, {"text": "drainage", "start": 78, "end": 86, "id": 16}, {"text": "vein", "start": 87, "end": 91, "id": 17}, {"text": "(", "start": 92, "end": 93, "id": 18}, {"text": "arrow", "start": 93, "end": 98, "id": 19}, {"text": ")", "start": 98, "end": 99, "id": 20}, {"text": ",", "start": 99, "end": 100, "id": 21}, {"text": "(", "start": 101, "end": 102, "id": 22}, {"text": "B", "start": 102, "end": 103, "id": 23}, {"text": "and", "start": 104, "end": 107, "id": 24}, {"text": "C", "start": 108, "end": 109, "id": 25}, {"text": ")", "start": 109, "end": 110, "id": 26}, {"text": "nidus", "start": 111, "end": 116, "id": 27}, {"text": "is", "start": 117, "end": 119, "id": 28}, {"text": "showed", "start": 120, "end": 126, "id": 29}, {"text": "(", "start": 127, "end": 128, "id": 30}, {"text": "asterisk", "start": 128, "end": 136, "id": 31}, {"text": ")", "start": 136, "end": 137, "id": 32}, {"text": ",", "start": 137, "end": 138, "id": 33}, {"text": "and", "start": 139, "end": 142, "id": 34}, {"text": "(", "start": 143, "end": 144, "id": 35}, {"text": "D", "start": 144, "end": 145, "id": 36}, {"text": ")", "start": 145, "end": 146, "id": 37}, {"text": "multiple", "start": 147, "end": 155, "id": 38}, {"text": "efferent", "start": 156, "end": 164, "id": 39}, {"text": "arteries", "start": 165, "end": 173, "id": 40}, {"text": "coming", "start": 174, "end": 180, "id": 41}, {"text": "from", "start": 181, "end": 185, "id": 42}, {"text": "hypogastric", "start": 186, "end": 197, "id": 43}, {"text": "and", "start": 198, "end": 201, "id": 44}, {"text": "external", "start": 202, "end": 210, "id": 45}, {"text": "iliac", "start": 211, "end": 216, "id": 46}, {"text": ".", "start": 216, "end": 217, "id": 47}, {"text": "AVM", "start": 218, "end": 221, "id": 48}, {"text": ",", "start": 221, "end": 222, "id": 49}, {"text": "arteriovenous", "start": 223, "end": 236, "id": 50}, {"text": "malformation", "start": 237, "end": 249, "id": 51}, {"text": ";", "start": 249, "end": 250, "id": 52}, {"text": "CT", "start": 251, "end": 253, "id": 53}, {"text": ",", "start": 253, "end": 254, "id": 54}, {"text": "computed", "start": 255, "end": 263, "id": 55}, {"text": "tomography", "start": 264, "end": 274, "id": 56}, {"text": ".", "start": 274, "end": 275, "id": 57}]}
{"pdf_hash": "582a4132e66955dc7dffbac2771be954c9a101ba", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig 3. Radiologic appearance of myxoid liposarcoma of the proximal thigh. (A) Coronal T2-weighted magnetic resonance image of 80-mm tumor (arrow) with characteristic high signal intensity. T1-weighted fat-suppressed axial magnetic resonance images of (B) pregadolinium and (C) postgadolinium contrast show avid and heterogeneous enhancement of tumor (arrow).", "width": 1026, "height": 964, "subcaptions": {"a": [32, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "c8c442b5-b6b8-4cb4-a67a-bc2bbe51e12e", "label": "a", "points": [[18.3, 17.6], [18.3, 954.4], [538.6, 954.4], [538.6, 17.6]], "color": "yellow"}, {"id": "a5f2c84f-def2-4c89-8df8-4a77d03b0181", "label": "b", "points": [[546.7, 20.9], [546.7, 479.5], [1008.6, 479.5], [1008.6, 20.9]], "color": "cyan"}, {"id": "1c6ef2c9-5aa1-4e62-88b1-f75a3dd4713d", "label": "c", "points": [[553.2, 487.6], [553.2, 941.5], [1003.7, 941.5], [1003.7, 487.6]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "3", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Radiologic", "start": 7, "end": 17, "id": 3}, {"text": "appearance", "start": 18, "end": 28, "id": 4}, {"text": "of", "start": 29, "end": 31, "id": 5}, {"text": "myxoid", "start": 32, "end": 38, "id": 6}, {"text": "liposarcoma", "start": 39, "end": 50, "id": 7}, {"text": "of", "start": 51, "end": 53, "id": 8}, {"text": "the", "start": 54, "end": 57, "id": 9}, {"text": "proximal", "start": 58, "end": 66, "id": 10}, {"text": "thigh", "start": 67, "end": 72, "id": 11}, {"text": ".", "start": 72, "end": 73, "id": 12}, {"text": "(", "start": 74, "end": 75, "id": 13}, {"text": "A", "start": 75, "end": 76, "id": 14}, {"text": ")", "start": 76, "end": 77, "id": 15}, {"text": "Coronal", "start": 78, "end": 85, "id": 16}, {"text": "T2-weighted", "start": 86, "end": 97, "id": 17}, {"text": "magnetic", "start": 98, "end": 106, "id": 18}, {"text": "resonance", "start": 107, "end": 116, "id": 19}, {"text": "image", "start": 117, "end": 122, "id": 20}, {"text": "of", "start": 123, "end": 125, "id": 21}, {"text": "80-mm", "start": 126, "end": 131, "id": 22}, {"text": "tumor", "start": 132, "end": 137, "id": 23}, {"text": "(", "start": 138, "end": 139, "id": 24}, {"text": "arrow", "start": 139, "end": 144, "id": 25}, {"text": ")", "start": 144, "end": 145, "id": 26}, {"text": "with", "start": 146, "end": 150, "id": 27}, {"text": "characteristic", "start": 151, "end": 165, "id": 28}, {"text": "high", "start": 166, "end": 170, "id": 29}, {"text": "signal", "start": 171, "end": 177, "id": 30}, {"text": "intensity", "start": 178, "end": 187, "id": 31}, {"text": ".", "start": 187, "end": 188, "id": 32}, {"text": "T1-weighted", "start": 189, "end": 200, "id": 33}, {"text": "fat", "start": 201, "end": 204, "id": 34}, {"text": "-", "start": 204, "end": 205, "id": 35}, {"text": "suppressed", "start": 205, "end": 215, "id": 36}, {"text": "axial", "start": 216, "end": 221, "id": 37}, {"text": "magnetic", "start": 222, "end": 230, "id": 38}, {"text": "resonance", "start": 231, "end": 240, "id": 39}, {"text": "images", "start": 241, "end": 247, "id": 40}, {"text": "of", "start": 248, "end": 250, "id": 41}, {"text": "(", "start": 251, "end": 252, "id": 42}, {"text": "B", "start": 252, "end": 253, "id": 43}, {"text": ")", "start": 253, "end": 254, "id": 44}, {"text": "pregadolinium", "start": 255, "end": 268, "id": 45}, {"text": "and", "start": 269, "end": 272, "id": 46}, {"text": "(", "start": 273, "end": 274, "id": 47}, {"text": "C", "start": 274, "end": 275, "id": 48}, {"text": ")", "start": 275, "end": 276, "id": 49}, {"text": "postgadolinium", "start": 277, "end": 291, "id": 50}, {"text": "contrast", "start": 292, "end": 300, "id": 51}, {"text": "show", "start": 301, "end": 305, "id": 52}, {"text": "avid", "start": 306, "end": 310, "id": 53}, {"text": "and", "start": 311, "end": 314, "id": 54}, {"text": "heterogeneous", "start": 315, "end": 328, "id": 55}, {"text": "enhancement", "start": 329, "end": 340, "id": 56}, {"text": "of", "start": 341, "end": 343, "id": 57}, {"text": "tumor", "start": 344, "end": 349, "id": 58}, {"text": "(", "start": 350, "end": 351, "id": 59}, {"text": "arrow", "start": 351, "end": 356, "id": 60}, {"text": ")", "start": 356, "end": 357, "id": 61}, {"text": ".", "start": 357, "end": 358, "id": 62}]}
{"pdf_hash": "36a15b2edce2d7bbc6f658f2da872998b85a2b1a", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2 (A-C): Pseudotumour in diseased kidney in a 45-year-old female patient, not diagnosed on CT or MR but correctly interpreted on DWI. (A) Coronal unenhanced CT image shows ill-defined, mildly hypodense, exophytic mass lesion (asterisk) in the lower pole of the right kidney. Contrast could not be administered because of renal dysfunction. (B) Axial T2-weighted MR image shows that the lesion is hyperintense (asterisk). Solid \"ball-type\" morphology and hyperintensity on T2-weighted image raised the suspicion of malignant mass on CT and MRI. (C) Axial ADC map (generated from DWI) demonstrates the lesion to be hyperintense (asterisk) suggesting no diffusion restriction within the lesion. Absence of diffusion restriction within a solid mass lesion ruled out malignancy. 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{"pdf_hash": "dfece165150c6ff5f497ef90a3937c6670f3d387", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. An X-ray diffraction pattern of an isolated human stratum corneum (SC) sheet obtained using the sample holder described in (a) and the enlarged image of the small angle region (b). Angular spread of the reflection corresponds to the extent of the orientation of the intercellular lipid layers (see text).", "width": 874, "height": 512, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40]}, "subfigures": [{"id": "688fd8a1-3f95-46f4-b5da-8f60b0196cec", "label": "a", "points": [[0.7, 5.3], [0.7, 509.2], [507.5, 509.2], [507.5, 5.3]], "color": "yellow"}, {"id": "9cee612d-e565-4674-943d-54713ec00492", "label": "b", "points": [[529.5, 82.6], [529.5, 427.8], [872, 427.8], [872, 82.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "An", "start": 10, "end": 12, "id": 3}, {"text": "X", "start": 13, "end": 14, "id": 4}, {"text": "-", "start": 14, "end": 15, "id": 5}, {"text": "ray", "start": 15, "end": 18, "id": 6}, {"text": "diffraction", "start": 19, "end": 30, "id": 7}, {"text": "pattern", "start": 31, "end": 38, "id": 8}, {"text": "of", "start": 39, "end": 41, "id": 9}, {"text": "an", "start": 42, "end": 44, "id": 10}, {"text": "isolated", "start": 45, "end": 53, "id": 11}, {"text": "human", "start": 54, "end": 59, "id": 12}, {"text": "stratum", "start": 60, "end": 67, "id": 13}, {"text": "corneum", "start": 68, "end": 75, "id": 14}, {"text": "(", "start": 76, "end": 77, "id": 15}, {"text": "SC", "start": 77, "end": 79, "id": 16}, {"text": ")", "start": 79, "end": 80, "id": 17}, {"text": "sheet", "start": 81, "end": 86, "id": 18}, {"text": "obtained", "start": 87, "end": 95, "id": 19}, {"text": "using", "start": 96, "end": 101, "id": 20}, {"text": "the", "start": 102, "end": 105, "id": 21}, {"text": "sample", "start": 106, "end": 112, "id": 22}, {"text": "holder", "start": 113, "end": 119, "id": 23}, {"text": "described", "start": 120, "end": 129, "id": 24}, {"text": "in", "start": 130, "end": 132, "id": 25}, {"text": "(", "start": 133, "end": 134, "id": 26}, {"text": "a", "start": 134, "end": 135, "id": 27}, {"text": ")", "start": 135, "end": 136, "id": 28}, {"text": "and", "start": 137, "end": 140, "id": 29}, {"text": "the", "start": 141, "end": 144, "id": 30}, {"text": "enlarged", "start": 145, "end": 153, "id": 31}, {"text": "image", "start": 154, "end": 159, "id": 32}, {"text": "of", "start": 160, "end": 162, "id": 33}, {"text": "the", "start": 163, "end": 166, "id": 34}, {"text": "small", "start": 167, "end": 172, "id": 35}, {"text": "angle", "start": 173, "end": 178, "id": 36}, {"text": "region", "start": 179, "end": 185, "id": 37}, {"text": "(", "start": 186, "end": 187, "id": 38}, {"text": "b", "start": 187, "end": 188, "id": 39}, {"text": ")", "start": 188, "end": 189, "id": 40}, {"text": ".", "start": 189, "end": 190, "id": 41}, {"text": "Angular", "start": 191, "end": 198, "id": 42}, {"text": "spread", "start": 199, "end": 205, "id": 43}, {"text": "of", "start": 206, "end": 208, "id": 44}, {"text": "the", "start": 209, "end": 212, "id": 45}, {"text": "reflection", "start": 213, "end": 223, "id": 46}, {"text": "corresponds", "start": 224, "end": 235, "id": 47}, {"text": "to", "start": 236, "end": 238, "id": 48}, {"text": "the", "start": 239, "end": 242, "id": 49}, {"text": "extent", "start": 243, "end": 249, "id": 50}, {"text": "of", "start": 250, "end": 252, "id": 51}, {"text": "the", "start": 253, "end": 256, "id": 52}, {"text": "orientation", "start": 257, "end": 268, "id": 53}, {"text": "of", "start": 269, "end": 271, "id": 54}, {"text": "the", "start": 272, "end": 275, "id": 55}, {"text": "intercellular", "start": 276, "end": 289, "id": 56}, {"text": "lipid", "start": 290, "end": 295, "id": 57}, {"text": "layers", "start": 296, "end": 302, "id": 58}, {"text": "(", "start": 303, "end": 304, "id": 59}, {"text": "see", "start": 304, "end": 307, "id": 60}, {"text": "text", "start": 308, "end": 312, "id": 61}, {"text": ")", "start": 312, "end": 313, "id": 62}, {"text": ".", "start": 313, "end": 314, "id": 63}]}
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{"pdf_hash": "a981f3e6814241f1d54935f24cc5b7b181d7cc53", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. (A) Endoscopic view of the protruding tumor in the gastric antrum. (B) Endoscopic ultrasound image of a 1.5x2.0-cm hypoechoic mass emanating from the muscularis propria with the typical appearance of gastrointestinal stromal tumor.", "width": 1014, "height": 480, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "18feab6c-0ed1-4ada-8018-24d3feb462cf", "label": "a", "points": [[9.6, 11.2], [9.6, 474.2], [477.4, 474.2], [477.4, 11.2]], "color": "yellow"}, {"id": "e57a3693-a3bb-45c8-9aba-83de034b52b8", "label": "b", "points": [[549.5, 474.2], [549.5, 9.6], [1009.2, 9.6], [1009.2, 474.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Endoscopic", "start": 14, "end": 24, "id": 6}, {"text": "view", "start": 25, "end": 29, "id": 7}, {"text": "of", "start": 30, "end": 32, "id": 8}, {"text": "the", "start": 33, "end": 36, "id": 9}, {"text": "protruding", "start": 37, "end": 47, "id": 10}, {"text": "tumor", "start": 48, "end": 53, "id": 11}, {"text": "in", "start": 54, "end": 56, "id": 12}, {"text": "the", "start": 57, "end": 60, "id": 13}, {"text": "gastric", "start": 61, "end": 68, "id": 14}, {"text": "antrum", "start": 69, "end": 75, "id": 15}, {"text": ".", "start": 75, "end": 76, "id": 16}, {"text": "(", "start": 77, "end": 78, "id": 17}, {"text": "B", "start": 78, "end": 79, "id": 18}, {"text": ")", "start": 79, "end": 80, "id": 19}, {"text": "Endoscopic", "start": 81, "end": 91, "id": 20}, {"text": "ultrasound", "start": 92, "end": 102, "id": 21}, {"text": "image", "start": 103, "end": 108, "id": 22}, {"text": "of", "start": 109, "end": 111, "id": 23}, {"text": "a", "start": 112, "end": 113, "id": 24}, {"text": "1.5x2.0-cm", "start": 114, "end": 124, "id": 25}, {"text": "hypoechoic", "start": 125, "end": 135, "id": 26}, {"text": "mass", "start": 136, "end": 140, "id": 27}, {"text": "emanating", "start": 141, "end": 150, "id": 28}, {"text": "from", "start": 151, "end": 155, "id": 29}, {"text": "the", "start": 156, "end": 159, "id": 30}, {"text": "muscularis", "start": 160, "end": 170, "id": 31}, {"text": "propria", "start": 171, "end": 178, "id": 32}, {"text": "with", "start": 179, "end": 183, "id": 33}, {"text": "the", "start": 184, "end": 187, "id": 34}, {"text": "typical", "start": 188, "end": 195, "id": 35}, {"text": "appearance", "start": 196, "end": 206, "id": 36}, {"text": "of", "start": 207, "end": 209, "id": 37}, {"text": "gastrointestinal", "start": 210, "end": 226, "id": 38}, {"text": "stromal", "start": 227, "end": 234, "id": 39}, {"text": "tumor", "start": 235, "end": 240, "id": 40}, {"text": ".", "start": 240, "end": 241, "id": 41}]}
{"pdf_hash": "1afef8d69d3fca677c91e34df13d1166327252f1", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 A\u2013D Coronal and sagittal sections of CT scans of the head post craniectomy, revealing the large calvarial defect. 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{"pdf_hash": "6c890e132e785de95fcd221bf941bcb3a18fe146", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Case No 1. (A) Sagittal MR image showing a cavernous malformation of the pons after the first haemorrhage. (B) and (C) Sagittal MR images after the second and third haemorrage shows an enlarging haematoma. (D-F) Intraoperative photographs. (D) After exposure the bulging aspect of the right lateral pons and subpial haemosiderin staining is visible (arrow). (E) The haematoma is removed and the cavernous malformation is identified. (F) After resection of the lesion the cavity is collapsed. 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{"pdf_hash": "b7bdd72cbe0d007be8dd8f9644f2c5be80a8fa4d", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Fig. 6. Massage-induced changes of intra-facial structures of a 39-year-old woman. (a) Distribution of FMCR changes. (b) Sagittal 3D-CT before facial massage. (c) Sagittal 3D-CT after facial massage. (d) Axial CT image before facial massage. (e) Axial CT image after facial massage. (1) Levator anguli oris muscle, (2) Zygomaticus minor muscle, (3) Orbicularis oris muscle, (4) Top of the cheek, (5) Levator labil superioris muscle, (6) Zygomaticus major muscle. Sagittal 3D-CT images show that the cheek top is moved upward by facial massage, and subcutaneous changes are seen. The thickness of the adipose tissue in the cheek is increased, and the configuration of the facial expression muscles is also changed. Axial CT images: Auxiliary lines are drawn in the same locations on both axial images. The skin surface has moved to the ventral side of the auxiliary lines (arrowheads) due to increase in thickness of the soft tissue after massage. The configuration of the facial expression muscles is also changed. 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{"pdf_hash": "5ae67e144907ca2bbca8ff631472daaab34832a7", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. A 42-year old male with right pyriform sinus carcinoma. The left panel is a coronal computed tomography scan of the larynx showing erosions of thyroid and cricoid cartilages. The intraoperative view is presented in the right panel, which indicates residual epiglottis, thyroid cartilage and cricoid cartilage following tailored vertical hemilaryngopharyngectomy with resection including a segment of the cricoid ring. 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{"pdf_hash": "67170eafb2d75019758267464be4f14df9bbfabd", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5. (A-C) Representative postcontrast T 1 -weighted M RIs of IDH1 WT , vector-control, and IDH1 R132 flank tumors. Notice areas void of contrast agent enhancement in all 3 tumor types. (D-F) Representative perfusion images (color scale represents different perfusion values, mL/ 100 mg tissue/ min) with DSC signal intensity bolus curve. Areas of reduced perfusion were present in all 3 tumor types, usually matched with areas of poor contrast enhancement. Some of the geometric distortion is due to use of echo planar imaging sequence for DSC perfusion. 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{"pdf_hash": "446dd7d9ff7d3f795cb973789405fc35ec52eab5", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Plain chest X-rays of the patient. a Deep inspiration. b Expiration. His chest X-ray showed almost no movement of the diaphragm at deep inspiration and expiration, indicating bilateral phrenic nerve palsy.", "width": 938, "height": 430, "subcaptions": {"a": [13, 14, 15, 16], "b": [17, 18, 19]}, "subfigures": [{"id": "36e1d248-0ec4-41b5-bab2-53d00e857cc6", "label": "a", "points": [[5.2, 4.2], [5.2, 425], [466.1, 425], [466.1, 4.2]], "color": "yellow"}, {"id": "26c0f2c4-e011-407e-82e3-b3a750556eea", "label": "b", "points": [[475, 2.7], [475, 426.5], [931.4, 426.5], [931.4, 2.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Plain", "start": 8, "end": 13, "id": 4}, {"text": "chest", "start": 14, "end": 19, "id": 5}, {"text": "X", "start": 20, "end": 21, "id": 6}, {"text": "-", "start": 21, "end": 22, "id": 7}, {"text": "rays", "start": 22, "end": 26, "id": 8}, {"text": "of", "start": 27, "end": 29, "id": 9}, {"text": "the", "start": 30, "end": 33, "id": 10}, {"text": "patient", "start": 34, "end": 41, "id": 11}, {"text": ".", "start": 41, "end": 42, "id": 12}, {"text": "a", "start": 43, "end": 44, "id": 13}, {"text": "Deep", "start": 45, "end": 49, "id": 14}, {"text": "inspiration", "start": 50, "end": 61, "id": 15}, {"text": ".", "start": 61, "end": 62, "id": 16}, {"text": "b", "start": 63, "end": 64, "id": 17}, {"text": "Expiration", "start": 65, "end": 75, "id": 18}, {"text": ".", "start": 75, "end": 76, "id": 19}, {"text": "His", "start": 77, "end": 80, "id": 20}, {"text": "chest", "start": 81, "end": 86, "id": 21}, {"text": "X", "start": 87, "end": 88, "id": 22}, {"text": "-", "start": 88, "end": 89, "id": 23}, {"text": "ray", "start": 89, "end": 92, "id": 24}, {"text": "showed", "start": 93, "end": 99, "id": 25}, {"text": "almost", "start": 100, "end": 106, "id": 26}, {"text": "no", "start": 107, "end": 109, "id": 27}, {"text": "movement", "start": 110, "end": 118, "id": 28}, {"text": "of", "start": 119, "end": 121, "id": 29}, {"text": "the", "start": 122, "end": 125, "id": 30}, {"text": "diaphragm", "start": 126, "end": 135, "id": 31}, {"text": "at", "start": 136, "end": 138, "id": 32}, {"text": "deep", "start": 139, "end": 143, "id": 33}, {"text": "inspiration", "start": 144, "end": 155, "id": 34}, {"text": "and", "start": 156, "end": 159, "id": 35}, {"text": "expiration", "start": 160, "end": 170, "id": 36}, {"text": ",", "start": 170, "end": 171, "id": 37}, {"text": "indicating", "start": 172, "end": 182, "id": 38}, {"text": "bilateral", "start": 183, "end": 192, "id": 39}, {"text": "phrenic", "start": 193, "end": 200, "id": 40}, {"text": "nerve", "start": 201, "end": 206, "id": 41}, {"text": "palsy", "start": 207, "end": 212, "id": 42}, {"text": ".", "start": 212, "end": 213, "id": 43}]}
{"pdf_hash": "0ce9db126816615c4675ace49cd0e049a8375f56", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Integration of MEG data into the frameless database. The locations of the MEG current dipoles representing the motor cortex (circles) and the sensory cortex (squares) are shown on an axial slice in the imaging database prior to (upper) and during (lower) the process of image registration.", "width": 666, "height": 818, "subcaptions": {"a": [44, 45, 46, 47, 48], "b": [50, 51, 52, 53]}, "subfigures": [{"id": "1955165b-3e39-43d1-b10f-69446f0134e7", "label": "a", "points": [[0, 1.1], [0, 414.5], [663.9, 414.5], [663.9, 1.1]], "color": "yellow"}, {"id": "a8bfb34a-a781-47dd-a1aa-034646019357", "label": "b", "points": [[1.1, 797.5], [1.1, 417.7], [661.8, 417.7], [661.8, 797.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Integration", "start": 8, "end": 19, "id": 4}, {"text": "of", "start": 20, "end": 22, "id": 5}, {"text": "MEG", "start": 23, "end": 26, "id": 6}, {"text": "data", "start": 27, "end": 31, "id": 7}, {"text": "into", "start": 32, "end": 36, "id": 8}, {"text": "the", "start": 37, "end": 40, "id": 9}, {"text": "frameless", "start": 41, "end": 50, "id": 10}, {"text": "database", "start": 51, "end": 59, "id": 11}, {"text": ".", "start": 59, "end": 60, "id": 12}, {"text": "The", "start": 61, "end": 64, "id": 13}, {"text": "locations", "start": 65, "end": 74, "id": 14}, {"text": "of", "start": 75, "end": 77, "id": 15}, {"text": "the", "start": 78, "end": 81, "id": 16}, {"text": "MEG", "start": 82, "end": 85, "id": 17}, {"text": "current", "start": 86, "end": 93, "id": 18}, {"text": "dipoles", "start": 94, "end": 101, "id": 19}, {"text": "representing", "start": 102, "end": 114, "id": 20}, {"text": "the", "start": 115, "end": 118, "id": 21}, {"text": "motor", "start": 119, "end": 124, "id": 22}, {"text": "cortex", "start": 125, "end": 131, "id": 23}, {"text": "(", "start": 132, "end": 133, "id": 24}, {"text": "circles", "start": 133, "end": 140, "id": 25}, {"text": ")", "start": 140, "end": 141, "id": 26}, {"text": "and", "start": 142, "end": 145, "id": 27}, {"text": "the", "start": 146, "end": 149, "id": 28}, {"text": "sensory", "start": 150, "end": 157, "id": 29}, {"text": "cortex", "start": 158, "end": 164, "id": 30}, {"text": "(", "start": 165, "end": 166, "id": 31}, {"text": "squares", "start": 166, "end": 173, "id": 32}, {"text": ")", "start": 173, "end": 174, "id": 33}, {"text": "are", "start": 175, "end": 178, "id": 34}, {"text": "shown", "start": 179, "end": 184, "id": 35}, {"text": "on", "start": 185, "end": 187, "id": 36}, {"text": "an", "start": 188, "end": 190, "id": 37}, {"text": "axial", "start": 191, "end": 196, "id": 38}, {"text": "slice", "start": 197, "end": 202, "id": 39}, {"text": "in", "start": 203, "end": 205, "id": 40}, {"text": "the", "start": 206, "end": 209, "id": 41}, {"text": "imaging", "start": 210, "end": 217, "id": 42}, {"text": "database", "start": 218, "end": 226, "id": 43}, {"text": "prior", "start": 227, "end": 232, "id": 44}, {"text": "to", "start": 233, "end": 235, "id": 45}, {"text": "(", "start": 236, "end": 237, "id": 46}, {"text": "upper", "start": 237, "end": 242, "id": 47}, {"text": ")", "start": 242, "end": 243, "id": 48}, {"text": "and", "start": 244, "end": 247, "id": 49}, {"text": "during", "start": 248, "end": 254, "id": 50}, {"text": "(", "start": 255, "end": 256, "id": 51}, {"text": "lower", "start": 256, "end": 261, "id": 52}, {"text": ")", "start": 261, "end": 262, "id": 53}, {"text": "the", "start": 263, "end": 266, "id": 54}, {"text": "process", "start": 267, "end": 274, "id": 55}, {"text": "of", "start": 275, "end": 277, "id": 56}, {"text": "image", "start": 278, "end": 283, "id": 57}, {"text": "registration", "start": 284, "end": 296, "id": 58}, {"text": ".", "start": 296, "end": 297, "id": 59}]}
{"pdf_hash": "08f5dcd4776de4d2a482f9d4f3516eb41cdbbb0f", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 (A) Three-dimensional image of CBCT revealing a fenestration alveolar bone defect at the #25 region. (B) Clinical photograph showing a fenestration alveolar bone defect at the #25 region. (C) Clinical photograph for platelet-rich fibrin application over #25 alveolar bone defect. (D) After 6 months, the socket was completely filled with a hard material, which on probing exhibited the consistency of bone. The CBCT images demonstrated the changes of bone density (E) immediately after #25 extraction and (F) 2 months, (G) 4 months, and (H) 6 months after platelet-rich fibrin application. 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{"pdf_hash": "6fc64af39e6534968ac6bcd26aadeb208ec681ce", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "FIGURE 5. Survival motor neuron (SMN) staining of developing ([A], arrowheads; TL antibody) and mature ([B]; 1137 antibody) pyramidal neurons. Note the preferential SMN nuclear staining of the developing cortical plate (A) and the SMN immunoreactivity at the axon hillock of mature layer V pyramidal neurons ([B], arrowheads). 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{"pdf_hash": "35765b32636421c7e219e0cd23e1c8e28e04d311", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. (A) Axial diffusion-weight (DW) and (B) axial apparent diffusion coefficient (ADC) brain MRI images.", "width": 554, "height": 1146, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13], "b": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24]}, "subfigures": [{"id": "3b60f965-a9d5-44f4-8c28-30ee060f1086", "label": "a", "points": [[6, 4.8], [6, 547.8], [541, 547.8], [541, 4.8]], "color": "yellow"}, {"id": "d18d25e5-f157-4401-82a5-82de92c956f7", "label": "b", "points": [[7, 554.3], [7, 1137.9], [548, 1137.9], [548, 554.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Axial", "start": 12, "end": 17, "id": 7}, {"text": "diffusion", "start": 18, "end": 27, "id": 8}, {"text": "-", "start": 27, "end": 28, "id": 9}, {"text": "weight", "start": 28, "end": 34, "id": 10}, {"text": "(", "start": 35, "end": 36, "id": 11}, {"text": "DW", "start": 36, "end": 38, "id": 12}, {"text": ")", "start": 38, "end": 39, "id": 13}, {"text": "and", "start": 40, "end": 43, "id": 14}, {"text": "(", "start": 44, "end": 45, "id": 15}, {"text": "B", "start": 45, "end": 46, "id": 16}, {"text": ")", "start": 46, "end": 47, "id": 17}, {"text": "axial", "start": 48, "end": 53, "id": 18}, {"text": "apparent", "start": 54, "end": 62, "id": 19}, {"text": "diffusion", "start": 63, "end": 72, "id": 20}, {"text": "coefficient", "start": 73, "end": 84, "id": 21}, {"text": "(", "start": 85, "end": 86, "id": 22}, {"text": "ADC", "start": 86, "end": 89, "id": 23}, {"text": ")", "start": 89, "end": 90, "id": 24}, {"text": "brain", "start": 91, "end": 96, "id": 25}, {"text": "MRI", "start": 97, "end": 100, "id": 26}, {"text": "images", "start": 101, "end": 107, "id": 27}, {"text": ".", "start": 107, "end": 108, "id": 28}]}
{"pdf_hash": "b4959598d4957f43fb8bfa51756c2be35930e878", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Figure 5. Cross-sections (z slices) taken from 3D maps of mforrn and dform NPCs after refinement by POCs/solvent flattening, a and c are slices cut along the putative spoke twofold axes; b and d are slices cut along along the putative radial arm twofold axes. b and d are related to a and c by a rotation of 22.5 \u00b0 around the central eightfold axis. (a) A z slice which bisects the spokes of the membrane-associated form is shown. Domains within the spokes are labeled including: inner spoke domain (IS), central domain (CS), lumenal domain (LS), the inner vertical domain (V/), and the outer vertical domain (I6). An area of weak interaction between the inner spoke domain and the central spoke domain is labeled (h). (b) A z slice which bisects the radial arms is shown. 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{"pdf_hash": "0854c957ec5b96f40789c9cc45cb591b07f66b62", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. High-power field of a serrated adenoma with high-grade dysplasia (A) in which there is aberrant nuclear expression of p53 (B) and loss of nuclear expression of O-6-methylguanine DNA methyltransferase (C).", "width": 1338, "height": 584, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 11]}, "subfigures": [{"id": "67cc0bd6-6281-41a5-ae64-f9b6b4bcba11", "label": "a", "points": [[430.2, 574.6], [430.2, 1.8], [5.4, 1.8], [5.4, 574.6]], "color": "yellow"}, {"id": "a7287e3a-e0bc-4565-877c-91087c8b4472", "label": "b", "points": [[457.7, 6], [457.7, 580.9], [880.4, 580.9], [880.4, 6]], "color": "cyan"}, {"id": "fd13b705-7b63-478e-b550-911a5ec29a57", "label": "c", "points": [[907.9, 3.9], [907.9, 578.8], [1330.6, 578.8], [1330.6, 3.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "High", "start": 10, "end": 14, "id": 3}, {"text": "-", "start": 14, "end": 15, "id": 4}, {"text": "power", "start": 15, "end": 20, "id": 5}, {"text": "field", "start": 21, "end": 26, "id": 6}, {"text": "of", "start": 27, "end": 29, "id": 7}, {"text": "a", "start": 30, "end": 31, "id": 8}, {"text": "serrated", "start": 32, "end": 40, "id": 9}, {"text": "adenoma", "start": 41, "end": 48, "id": 10}, {"text": "with", "start": 49, "end": 53, "id": 11}, {"text": "high", "start": 54, "end": 58, "id": 12}, {"text": "-", "start": 58, "end": 59, "id": 13}, {"text": "grade", "start": 59, "end": 64, "id": 14}, {"text": "dysplasia", "start": 65, "end": 74, "id": 15}, {"text": "(", "start": 75, "end": 76, "id": 16}, {"text": "A", "start": 76, "end": 77, "id": 17}, {"text": ")", "start": 77, "end": 78, "id": 18}, {"text": "in", "start": 79, "end": 81, "id": 19}, {"text": "which", "start": 82, "end": 87, "id": 20}, {"text": "there", "start": 88, "end": 93, "id": 21}, {"text": "is", "start": 94, "end": 96, "id": 22}, {"text": "aberrant", "start": 97, "end": 105, "id": 23}, {"text": "nuclear", "start": 106, "end": 113, "id": 24}, {"text": "expression", "start": 114, "end": 124, "id": 25}, {"text": "of", "start": 125, "end": 127, "id": 26}, {"text": "p53", "start": 128, "end": 131, "id": 27}, {"text": "(", "start": 132, "end": 133, "id": 28}, {"text": "B", "start": 133, "end": 134, "id": 29}, {"text": ")", "start": 134, "end": 135, "id": 30}, {"text": "and", "start": 136, "end": 139, "id": 31}, {"text": "loss", "start": 140, "end": 144, "id": 32}, {"text": "of", "start": 145, "end": 147, "id": 33}, {"text": "nuclear", "start": 148, "end": 155, "id": 34}, {"text": "expression", "start": 156, "end": 166, "id": 35}, {"text": "of", "start": 167, "end": 169, "id": 36}, {"text": "O-6-methylguanine", "start": 170, "end": 187, "id": 37}, {"text": "DNA", "start": 188, "end": 191, "id": 38}, {"text": "methyltransferase", "start": 192, "end": 209, "id": 39}, {"text": "(", "start": 210, "end": 211, "id": 40}, {"text": "C", "start": 211, "end": 212, "id": 41}, {"text": ")", "start": 212, "end": 213, "id": 42}, {"text": ".", "start": 213, "end": 214, "id": 43}]}
{"pdf_hash": "389c9b93a5030e99996e82291f2746b9f01832dc", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Patient 1. Comparison of the MR image of the brain and neuropathological examination. A) Second MRI, FSE/T2WI/coronal plane. Radiating pattern with normal signal intensity along the perivascular spaces in the white matter of both cerebral hemispheres. The cavitary lesions in the internal capsules. Lesions in the cerebral peduncles. Cerebral and cerebellar atrophy. B) Macroscopic coronal section of the hemispheres. Damage of white matter of corona radiata. Bilateral symmetrical cavities in the posterior limb of the internal capsule and in corpus callosum. 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{"pdf_hash": "810cbbe03a9e6c420d9ce6cd61222f9079ca194f", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4 Schematic drawing (a) and ultrasound image (b) demonstrating our proposed ultrasound definition of the rectovaginal septum (RVS). (a) The RVS is denoted by the double-headed green arrow, below (anatomically) the blue line passing along the lower border of the posterior lip of the cervix. The posterior vaginal fornix lies between the blue line and the red line (the latter passing along the caudal end of the peritoneum of the lower margin of the rectouterine peritoneal pouch (cul-de-sac of Douglas)). 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{"pdf_hash": "096950a8b829610bf35a0ed02a5de1f7fad9b3c8", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig. 3. Testicular ultrasound with bilateral color flow. (A) Right testicle. (B) Left testicle.", "width": 888, "height": 472, "subcaptions": {"a": [11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22]}, "subfigures": [{"id": "f0035912-4c95-441a-97d3-d85166c3e80c", "label": "a", "points": [[27.4, 19.4], [27.4, 440.3], [399.2, 440.3], [399.2, 19.4]], "color": "yellow"}, {"id": "2d8184db-e6e5-4953-930b-5ccaa01f6078", "label": "b", "points": [[410.4, 29.2], [410.4, 447.3], [884.5, 447.3], [884.5, 29.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Testicular", "start": 8, "end": 18, "id": 4}, {"text": "ultrasound", "start": 19, "end": 29, "id": 5}, {"text": "with", "start": 30, "end": 34, "id": 6}, {"text": "bilateral", "start": 35, "end": 44, "id": 7}, {"text": "color", "start": 45, "end": 50, "id": 8}, {"text": "flow", "start": 51, "end": 55, "id": 9}, {"text": ".", "start": 55, "end": 56, "id": 10}, {"text": "(", "start": 57, "end": 58, "id": 11}, {"text": "A", "start": 58, "end": 59, "id": 12}, {"text": ")", "start": 59, "end": 60, "id": 13}, {"text": "Right", "start": 61, "end": 66, "id": 14}, {"text": "testicle", "start": 67, "end": 75, "id": 15}, {"text": ".", "start": 75, "end": 76, "id": 16}, {"text": "(", "start": 77, "end": 78, "id": 17}, {"text": "B", "start": 78, "end": 79, "id": 18}, {"text": ")", "start": 79, "end": 80, "id": 19}, {"text": "Left", "start": 81, "end": 85, "id": 20}, {"text": "testicle", "start": 86, "end": 94, "id": 21}, {"text": ".", "start": 94, "end": 95, "id": 22}]}
{"pdf_hash": "5508e52e7e4e9695410cc9ad73a6d9af75375d92", "fig_key": "Figure18", "fig_uri": "13-Figure18-1.png", "text": "Fig. 18.\u2014 Sagittal (A), axial (B), coronal (C) and oblique (D) MPR views of the epigastric area obtained in a 54-year-old patient presenting with unusual epigastric pain amplified during deep inspiration. Ultrasonography (not illustrated) was uncontributive but unenhanced MDCT revealed oedema and inflammatory changes of the anteroinferior portion of the lesser omentum. A segmental infarction of the lesser omentum was diagnosed. The evolution was sponteanously resolutive in a few weeks.", "width": 908, "height": 846, "subcaptions": {"a": [5, 6, 7, 8], "b": [10, 11, 12, 13], "c": [15, 16, 17, 18], "d": [20, 21, 22, 23]}, "subfigures": [{"id": "aafc79a6-99ca-4e79-9ebc-03fe9fb95f61", "label": "a", "points": [[-0.7, 5.5], [-0.7, 411.4], [454, 411.4], [454, 5.5]], "color": "yellow"}, {"id": "af8c4245-9c19-44af-98bc-03a9fbc66f38", "label": "b", "points": [[469.8, 5.5], [469.8, 401.4], [904.4, 401.4], [904.4, 5.5]], "color": "cyan"}, {"id": "973674b4-07eb-40f8-b7cd-5149148052cd", "label": "c", "points": [[5.1, 428.6], [5.1, 843.2], [454, 843.2], [454, 428.6]], "color": "magenta"}, {"id": "a665c223-6a33-4934-be76-647c927266db", "label": "d", "points": [[475.6, 425.8], [475.6, 838.9], [900.1, 838.9], [900.1, 425.8]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "18", "start": 5, "end": 7, "id": 2}, {"text": ".", "start": 7, 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{"pdf_hash": "ceceb80730e02ebec807061ace6346109b7a6a4d", "fig_key": "Figure15", "fig_uri": "9-Figure15-1.png", "text": "Fig. 15. Habermeyer group 3 lesion in 38-year-old woman. A, B. Consecutive axial fat-saturated T1-weighted MR arthrographic images show superior GHL lesion (white arrow) with partial tear on articularside of subscapularis tendon (white arrowheads). LHBT (white dotted arrow) shows slight medial subluxation. C. Oblique sagittal fat-saturated T1-weighted MR arthrographic image shows contrast agent entering defect (arrowhead) of superior subscapularis tendon (SSC), consistent with partial tear. LHBT (white dotted arrow) shows contact with superior border of SSC on midsection through lesser tuberosity. 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{"pdf_hash": "620aedd8b05602fd2cfe1a4e7ea6f9027401ef1f", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Analysis of the expression and knockdown efficiency of a5b1 integrin in the developing murine neocortex. (A) In situ hybridization of coronal brain sections at E14.5 revealed a signal in the VZ \u2044 SVZ for the a5 subunit; the signal for the b1 subunit was widespread throughout the laminar structure of the cerebral cortex and visible in the VZ and SVZ in some areas. Scale bar, 500 lm. (B, C) pcDNA3.1 vector containing an a5 (B) or a6 (C) integrin murine cDNA was cotransfected into HeLa cells with pRNAT-U6.1 \u2044Neo empty vector, the control construct (Ctr), or two different shRNA constructs targeting mouse a5 integrin (R1 and R7). Forty-eight hours after transfection, cells were lysed and were subjected to immunoblotting for a5 integrin or a6 integrin. GAPDH and GFP are, respectively, loading and transfection efficiency controls. a5-shRNA constructs were able to decrease a5 integrin expression by 80% (R1) and 40% (R7) but had no detectable effect on expression of the a6 integrin subunit. (D) High magnification of the VZ of E18.5 brain sections after electroporation with R1 a5-shRNA. Immunostaining for a5 integrin (red) and GFP (green) showed a reduction of endogenous a5 integrin expression in the cortical neuronal progenitors compared with the control brain. Scale bar, 50 lm. 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{"pdf_hash": "3bb1c1f3a470bfa81aeeb221ef94022ff1509a5c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (A) Computed tomography (CT) and (B) PET-CT images of a FDG-avid (SUV = 26) typical bronchogenic carcinoid.", "width": 676, "height": 862, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10], "b": [12, 13, 14, 15, 16, 17]}, "subfigures": [{"id": "5a746350-2962-4cf0-91f7-17c0177ff9aa", "label": "a", "points": [[23.8, 4.1], [23.8, 459], [658.1, 459], [658.1, 4.1]], "color": "yellow"}, {"id": "f301db51-e6b0-4067-a49f-385a4b08128b", "label": "b", "points": [[28.1, 469.7], [28.1, 828.5], [659.2, 828.5], [659.2, 469.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Computed", "start": 14, "end": 22, "id": 6}, {"text": "tomography", "start": 23, "end": 33, "id": 7}, {"text": "(", "start": 34, "end": 35, "id": 8}, {"text": "CT", "start": 35, "end": 37, "id": 9}, {"text": ")", "start": 37, "end": 38, "id": 10}, {"text": "and", "start": 39, "end": 42, "id": 11}, {"text": "(", "start": 43, "end": 44, "id": 12}, {"text": "B", "start": 44, "end": 45, "id": 13}, {"text": ")", "start": 45, "end": 46, "id": 14}, {"text": "PET", "start": 47, "end": 50, "id": 15}, {"text": "-", "start": 50, "end": 51, "id": 16}, {"text": "CT", "start": 51, "end": 53, "id": 17}, {"text": "images", "start": 54, "end": 60, "id": 18}, {"text": "of", "start": 61, "end": 63, "id": 19}, {"text": "a", "start": 64, "end": 65, "id": 20}, {"text": "FDG", "start": 66, "end": 69, "id": 21}, {"text": "-", "start": 69, "end": 70, "id": 22}, {"text": "avid", "start": 70, "end": 74, "id": 23}, {"text": "(", "start": 75, "end": 76, "id": 24}, {"text": "SUV", "start": 76, "end": 79, "id": 25}, {"text": "=", "start": 80, "end": 81, "id": 26}, {"text": "26", "start": 82, "end": 84, "id": 27}, {"text": ")", "start": 84, "end": 85, "id": 28}, {"text": "typical", "start": 86, "end": 93, "id": 29}, {"text": "bronchogenic", "start": 94, "end": 106, "id": 30}, {"text": "carcinoid", "start": 107, "end": 116, "id": 31}, {"text": ".", "start": 116, "end": 117, "id": 32}]}
{"pdf_hash": "51a70d51e617750e238ed8810c32b2dbea9a12c4", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Figure 6. A 21-years old man with bilateral hand muscles weakness, neutral MRI sagittal T2WI (a) showed focal lower cervical cord atrophy without cord hyperintensities. Axial T2WI (b, c) showed anterior flattening of lower cervical cord (arrow), postgadolinium sagittal flexion MRI T1WI (d) showed anterior displacement of posterior dura matter with enhancing posterior epidural lesion and T1 hypointense cerebrospinal fluid flow voids within (block arrow)", "width": 620, "height": 448, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [32, 33, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 30, 31], "c": [32, 35, 36, 37, 38, 39, 40, 41, 42, 43, 30, 31], "d": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79]}, "subfigures": [{"id": "677d2ed1-e03d-47db-b2e0-3d293e7d2f1f", "label": "a", "points": [[5.5, 2], [5.5, 428], [161.5, 428], [161.5, 2]], "color": "yellow"}, {"id": "b8e00dda-1562-4ace-bb0f-54563566d20b", "label": "b", "points": [[353.5, 3], [353.5, 214], [163.5, 214], [163.5, 3]], "color": "cyan"}, {"id": 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{"pdf_hash": "f6a3c62774c40f84be3415cbadf94dc2febfd297", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Classification of the orbitofrontal cortex sulcogyral patterns with magnetic resonance imaging. Examples of the four major sulcogyral patterns from four different participants. Patterns were classified into four subtypes (Types I\u2013IV) according to the continuity of the lateral and medial orbital sulci (LOS and MOS, respectively) in the rostrocaudal direction (r rostral, c caudal). Type I refers to continuous LOS and discontinuous MOS (a), Type II refers to continuous LOS and MOS (b), Type III refers to discontinuous LOS and MOS (c), and Type IV refers to continuous MOS and discontinuous LOS (d). Sulcal continuities of the MOS and LOS were determined by evaluating several consecutive axial slices rather than just a single slice. TOS transverse orbital sulcus", "width": 1342, "height": 588, "subcaptions": {"a": [69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80], "b": [82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92], "c": [94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104], "d": [107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118]}, "subfigures": [{"id": "85d65715-af3f-4dea-a059-6dc2f5b9171b", "label": "a", "points": [[26.6, 65.4], [26.6, 559.3], [319.1, 559.3], [319.1, 65.4]], "color": "yellow"}, {"id": "4a37734a-ca65-4d0c-a1c9-8620ac7644cc", "label": "b", "points": [[357.3, 63.3], [357.3, 555.1], [660.5, 555.1], [660.5, 63.3]], "color": "cyan"}, {"id": "f2367290-a086-41d9-9c6e-184bebe34482", "label": "c", "points": [[688, 63.3], [688, 555.1], [999.7, 555.1], [999.7, 63.3]], "color": "magenta"}, {"id": "2565da11-a187-4df2-9542-18ec24a33245", "label": "d", "points": [[1012.4, 69.6], [1012.4, 569.9], [1324, 569.9], [1324, 69.6]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, 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{"pdf_hash": "eda0c71dd0a0ef5a9a811f71b1cfa035b829bdf4", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 Lateral trochlear inclination measurement on axial MRI. It is the angle between a line tangential to the subchondral bone of the posterior aspect of the femoral condyles and a line along the lateral trochlear facet. a Normal trochlea. b Trochlear dysplasia (9\u00b0 inclination)", "width": 856, "height": 468, "subcaptions": {"a": [40, 41, 42, 43], "b": [44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "954da126-2698-4ee7-a821-654b304eac70", "label": "a", "points": [[39.4, 22.1], [39.4, 433.2], [437, 433.2], [437, 22.1]], "color": "yellow"}, {"id": "168be620-a220-4f75-8063-f287ba52a2d3", "label": "b", "points": [[439.7, 16.7], [439.7, 435.9], [821.1, 435.9], [821.1, 16.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Lateral", "start": 7, "end": 14, "id": 3}, {"text": "trochlear", "start": 15, "end": 24, "id": 4}, {"text": "inclination", "start": 25, "end": 36, "id": 5}, {"text": "measurement", "start": 37, "end": 48, "id": 6}, {"text": "on", "start": 49, "end": 51, "id": 7}, {"text": "axial", "start": 52, "end": 57, "id": 8}, {"text": "MRI", "start": 58, "end": 61, "id": 9}, {"text": ".", "start": 61, "end": 62, "id": 10}, {"text": "It", "start": 63, "end": 65, "id": 11}, {"text": "is", "start": 66, "end": 68, "id": 12}, {"text": "the", "start": 69, "end": 72, "id": 13}, {"text": "angle", "start": 73, "end": 78, "id": 14}, {"text": "between", "start": 79, "end": 86, "id": 15}, {"text": "a", "start": 87, "end": 88, "id": 16}, {"text": "line", "start": 89, "end": 93, "id": 17}, {"text": "tangential", "start": 94, "end": 104, "id": 18}, {"text": "to", "start": 105, "end": 107, "id": 19}, {"text": "the", "start": 108, "end": 111, "id": 20}, {"text": "subchondral", "start": 112, "end": 123, "id": 21}, {"text": "bone", "start": 124, "end": 128, "id": 22}, {"text": "of", "start": 129, "end": 131, "id": 23}, {"text": "the", "start": 132, "end": 135, "id": 24}, {"text": "posterior", "start": 136, "end": 145, "id": 25}, {"text": "aspect", "start": 146, "end": 152, "id": 26}, {"text": "of", "start": 153, "end": 155, "id": 27}, {"text": "the", "start": 156, "end": 159, "id": 28}, {"text": "femoral", "start": 160, "end": 167, "id": 29}, {"text": "condyles", "start": 168, "end": 176, "id": 30}, {"text": "and", "start": 177, "end": 180, "id": 31}, {"text": "a", "start": 181, "end": 182, "id": 32}, {"text": "line", "start": 183, "end": 187, "id": 33}, {"text": "along", "start": 188, "end": 193, "id": 34}, {"text": "the", "start": 194, "end": 197, "id": 35}, {"text": "lateral", "start": 198, "end": 205, "id": 36}, {"text": "trochlear", "start": 206, "end": 215, "id": 37}, {"text": "facet", "start": 216, "end": 221, "id": 38}, {"text": ".", "start": 221, "end": 222, "id": 39}, {"text": "a", "start": 223, "end": 224, "id": 40}, {"text": "Normal", "start": 225, "end": 231, "id": 41}, {"text": "trochlea", "start": 232, "end": 240, "id": 42}, {"text": ".", "start": 240, "end": 241, "id": 43}, {"text": "b", "start": 242, "end": 243, "id": 44}, {"text": "Trochlear", "start": 244, "end": 253, "id": 45}, {"text": "dysplasia", "start": 254, "end": 263, "id": 46}, {"text": "(", "start": 264, "end": 265, "id": 47}, {"text": "9", "start": 265, "end": 266, "id": 48}, {"text": "\u00b0", "start": 266, "end": 267, "id": 49}, {"text": "inclination", "start": 268, "end": 279, "id": 50}, {"text": ")", "start": 279, "end": 280, "id": 51}]}
{"pdf_hash": "180244a49ca58e6e42d3da49277b864a9e927197", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig 2. Dimensions of the MF. (A) Long diameter (1), Short diameter (2). (B) CBCT sagittal reconstructed slices of the mandible to show the long and short diameters of the MF. https://doi.org/10.1371/journal.pone.0179704.g002", "width": 848, "height": 1414, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43]}, "subfigures": [{"id": "6b649155-bbff-446d-8ff0-2095b7418e15", "label": "a", "points": [[3.4, 6.5], [3.4, 670.9], [825.9, 670.9], [825.9, 6.5]], "color": "yellow"}, {"id": "d7f0a151-f373-4fc1-b1d9-0097329f3176", "label": "b", "points": [[4.7, 678.9], [4.7, 1386.2], [827.2, 1386.2], [827.2, 678.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Dimensions", "start": 7, "end": 17, "id": 3}, {"text": "of", "start": 18, "end": 20, "id": 4}, {"text": "the", "start": 21, "end": 24, "id": 5}, {"text": "MF", "start": 25, "end": 27, "id": 6}, {"text": ".", "start": 27, "end": 28, "id": 7}, {"text": "(", "start": 29, "end": 30, "id": 8}, {"text": "A", "start": 30, "end": 31, "id": 9}, {"text": ")", "start": 31, "end": 32, "id": 10}, {"text": "Long", "start": 33, "end": 37, "id": 11}, {"text": "diameter", "start": 38, "end": 46, "id": 12}, {"text": "(", "start": 47, "end": 48, "id": 13}, {"text": "1", "start": 48, "end": 49, "id": 14}, {"text": ")", "start": 49, "end": 50, "id": 15}, {"text": ",", "start": 50, "end": 51, "id": 16}, {"text": "Short", "start": 52, "end": 57, "id": 17}, {"text": "diameter", "start": 58, "end": 66, "id": 18}, {"text": "(", "start": 67, "end": 68, "id": 19}, {"text": "2", "start": 68, "end": 69, "id": 20}, {"text": ")", "start": 69, "end": 70, "id": 21}, {"text": ".", "start": 70, "end": 71, "id": 22}, {"text": "(", "start": 72, "end": 73, "id": 23}, {"text": "B", "start": 73, "end": 74, "id": 24}, {"text": ")", "start": 74, "end": 75, "id": 25}, {"text": "CBCT", "start": 76, "end": 80, "id": 26}, {"text": "sagittal", "start": 81, "end": 89, "id": 27}, {"text": "reconstructed", "start": 90, "end": 103, "id": 28}, {"text": "slices", "start": 104, "end": 110, "id": 29}, {"text": "of", "start": 111, "end": 113, "id": 30}, {"text": "the", "start": 114, "end": 117, "id": 31}, {"text": "mandible", "start": 118, "end": 126, "id": 32}, {"text": "to", "start": 127, "end": 129, "id": 33}, {"text": "show", "start": 130, "end": 134, "id": 34}, {"text": "the", "start": 135, "end": 138, "id": 35}, {"text": "long", "start": 139, "end": 143, "id": 36}, {"text": "and", "start": 144, "end": 147, "id": 37}, {"text": "short", "start": 148, "end": 153, "id": 38}, {"text": "diameters", "start": 154, "end": 163, "id": 39}, {"text": "of", "start": 164, "end": 166, "id": 40}, {"text": "the", "start": 167, "end": 170, "id": 41}, {"text": "MF", "start": 171, "end": 173, "id": 42}, {"text": ".", "start": 173, "end": 174, "id": 43}, {"text": "https://doi.org/10.1371/journal.pone.0179704.g002", "start": 175, "end": 224, "id": 44}]}
{"pdf_hash": "662e68c945a5305bb042fed753cfa03932725395", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. StructuralMRI brain scans of the patient. Top panels show coronal sections through the brain of patient AMat the level of themid-temporal lobe for each year. Running vertically below each year\u2019s coronal section are further axial and coronal sections from that year\u2019s MRI scan superimposed on which are the results of the VBM analysis for t ppare a and Ta", "width": 912, "height": 1156, "subcaptions": {"a": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "e2d4bc5b-b379-4181-a92a-0b40b1e0de6a", "label": "a", "points": [[6.5, 4.8], [6.5, 297.3], [306.2, 297.3], [306.2, 4.8]], "color": "yellow"}, {"id": "fab56580-c949-4b32-a46f-0a5df267fdea", "label": "d", "points": [[-0.7, 382.3], [-0.7, 620], [277.4, 620], [277.4, 382.3]], "color": "springgreen"}, {"id": "0356324c-774a-4ae6-a003-01c9601c34c6", "label": "a", "points": [[316.3, 4.8], [316.3, 304.5], [608.7, 304.5], [608.7, 4.8]], "color": "cyan"}, {"id": "a9ec1a72-036e-4fdb-9369-7a85c2f5aeb2", "label": "a", "points": [[620.3, 7.7], [620.3, 301.6], [907, 301.6], [907, 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{"pdf_hash": "216841e27a25fab4a52410b040010094ecc56808", "fig_key": "Figure2", "fig_uri": "1-Figure2-1.png", "text": "Figure 2 MRI, T2-weighted axial (A) and coronal (B) views of the right foot. Note the increased signal intensity at the second metatarsal head.", "width": 542, "height": 1166, "subcaptions": {"a": [5, 6, 7, 8], "b": [10, 11, 12, 13]}, "subfigures": [{"id": "35acd439-1cdf-49c7-a421-e5a848efc525", "label": "a", "points": [[8, 23.8], [8, 438.8], [538, 438.8], [538, 23.8]], "color": "yellow"}, {"id": "d117e071-172a-403f-88f3-c1950e1e7213", "label": "b", "points": [[11, 508.8], [11, 1135.9], [539, 1135.9], [539, 508.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "MRI", "start": 9, "end": 12, "id": 2}, {"text": ",", "start": 12, "end": 13, "id": 3}, {"text": "T2-weighted", "start": 14, "end": 25, "id": 4}, {"text": "axial", "start": 26, "end": 31, "id": 5}, {"text": "(", "start": 32, "end": 33, "id": 6}, {"text": "A", "start": 33, "end": 34, "id": 7}, {"text": ")", "start": 34, "end": 35, "id": 8}, {"text": "and", "start": 36, "end": 39, "id": 9}, {"text": "coronal", "start": 40, "end": 47, "id": 10}, {"text": "(", "start": 48, "end": 49, "id": 11}, {"text": "B", "start": 49, "end": 50, "id": 12}, {"text": ")", "start": 50, "end": 51, "id": 13}, {"text": "views", "start": 52, "end": 57, "id": 14}, {"text": "of", "start": 58, "end": 60, "id": 15}, {"text": "the", "start": 61, "end": 64, "id": 16}, {"text": "right", "start": 65, "end": 70, "id": 17}, {"text": "foot", "start": 71, "end": 75, "id": 18}, {"text": ".", "start": 75, "end": 76, "id": 19}, {"text": "Note", "start": 77, "end": 81, "id": 20}, {"text": "the", "start": 82, "end": 85, "id": 21}, {"text": "increased", "start": 86, "end": 95, "id": 22}, {"text": "signal", "start": 96, "end": 102, "id": 23}, {"text": "intensity", "start": 103, "end": 112, "id": 24}, {"text": "at", "start": 113, "end": 115, "id": 25}, {"text": "the", "start": 116, "end": 119, "id": 26}, {"text": "second", "start": 120, "end": 126, "id": 27}, {"text": "metatarsal", "start": 127, "end": 137, "id": 28}, {"text": "head", "start": 138, "end": 142, "id": 29}, {"text": ".", "start": 142, "end": 143, "id": 30}]}
{"pdf_hash": "5a0991ca19c17d54ed6673e61bb6d27da3eb4d94", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Serial ultrasonic images of the medial gastrocnemius muscle under CM conditions The muscle belly of the medial gastrocnemius was scanned (top). The fascicles of the gastrocnemius (the line in each image was drawn along the fascicle in the centre of image) can be seen between the superficial (proximal) and deep (distal) aponeuroses (white horizontal echoes). The images were recorded at 65 Hz. In this figure, serial images were curtailed and arranged sequentially, the value to the right of each image shows the time before toe-off (end of movement). To the far right images of the foot position in relation to the recordings are also shown. It can be seen that fascicle length is longest at transition from dorsiflexion to plantar flexion.", "width": 750, "height": 1274, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110], "c": [111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128]}, "subfigures": [{"id": "749ca0d0-f95c-48e2-b963-ae60e431a055", "label": "a", "points": [[439, 216.6], [439, 3.4], [5.4, 3.4], [5.4, 216.6]], "color": "yellow"}, {"id": "be4bb112-3034-4915-b260-29bc224eddaa", "label": "b", "points": [[17.2, 229.9], [17.2, 1269], [521.9, 1269], [521.9, 229.9]], "color": "cyan"}, {"id": 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{"pdf_hash": "fda83a13078ff19642d5d2d89e150c38ac044d50", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Magnetic resonance imaging findings of accessory breast tissue in a 42-year-old woman with invasive ductal carcinoma of the left breast. A, Sonogram showing accessory breast tissue in the right axilla. B and C, Axial T1-weighted (B) and T2-weighted (C) MRI showing accessory breast tissue (arrows) with a signal intensity similar to that of the rest of the breast parenchyma. D and E, Axial contrast-enhanced fat-suppressed subtraction T1-weighted MRI showing the accessory breast tissue (arrow) with contrast enhancement similar to the background parenchymal enhancement of the breast. A biopsy-confirmed malignancy (arrowhead) is shown in the left breast.", "width": 1068, "height": 450, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 26, 27, 28, 29, 30, 31], "b": [38, 42, 43, 44, 45, 46, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74], "c": [40, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74], "d": [75, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108], "e": [77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124]}, "subfigures": [{"id": "96552816-b742-420b-8785-8ade938eca7f", "label": "a", "points": [[8.9, 31.8], [8.9, 244.4], [326.1, 244.4], [326.1, 31.8]], "color": "yellow"}, {"id": "7d0062e5-7c29-4628-9ce6-af4f23c4c133", "label": "b", 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{"pdf_hash": "4e84c59206a645887ad0fa8bc7171785f18cbd54", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. A: Electrocardiogram demonstrating normal sinus rhythm with left deviation of the heart axis. B: Bulging contour of the left superior cardiac border. C: Apical four chamber view: echocardiography showed a laterally displaced left ventricular apex. 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{"pdf_hash": "8a7ffd49b25a26fe23c17b5680d918ca0ebb332d", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. 53-year-old man with paraaortic lesion. A. Diagnostic axial contrast enhanced CT scan that was obtained prior to biopsy procedure with patient in supine position shows 2-cm paraaortic mass lesion (arrow). B. Initial axial CT scan obtained with patient in prone position shows tracking scale crossing retrocaval mass lesion. Distance from skin to leading edge of lesion was 10 cm. C. CT fluoroscopic image obtained during biopsy procedure shows safe insertion of biopsy needle (arrow) into lesion. Pathologic diagnosis was nodular sclerosis of Hodgkin\u2019s disease. D. 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{"pdf_hash": "d91d2876a581f99b8c631e819073ddceecc65be2", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Patient presenting with a swelling of the first digit inter-phalangeal joint. Late phase bone scintigraphy (a): increased fixation centered on the extremity of the first digit. Standard radiograph (b): demineralization of the phalanx, thinning of the external border of the proximal cortex of the first pharynx indicating early dactylitis.", "width": 1284, "height": 664, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "b707941d-80e3-4d3a-91bb-5245fa5c1ad9", "label": "a", "points": [[2.6, 1.8], [2.6, 652.9], [454.9, 652.9], [454.9, 1.8]], "color": "yellow"}, {"id": "a7841434-174c-4985-88e2-4f0d57bcf3ae", "label": "b", "points": [[465.1, 3.8], [465.1, 661], [1270.4, 661], [1270.4, 3.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Patient", "start": 10, "end": 17, "id": 3}, {"text": "presenting", "start": 18, "end": 28, "id": 4}, {"text": "with", "start": 29, "end": 33, "id": 5}, {"text": "a", "start": 34, "end": 35, "id": 6}, {"text": "swelling", "start": 36, "end": 44, "id": 7}, {"text": "of", "start": 45, "end": 47, "id": 8}, {"text": "the", "start": 48, "end": 51, "id": 9}, {"text": "first", "start": 52, "end": 57, "id": 10}, {"text": "digit", "start": 58, "end": 63, "id": 11}, {"text": "inter", "start": 64, "end": 69, "id": 12}, {"text": "-", "start": 69, "end": 70, "id": 13}, {"text": "phalangeal", "start": 70, "end": 80, "id": 14}, {"text": "joint", "start": 81, "end": 86, "id": 15}, {"text": ".", "start": 86, "end": 87, "id": 16}, {"text": "Late", "start": 88, "end": 92, "id": 17}, {"text": "phase", "start": 93, "end": 98, "id": 18}, {"text": "bone", "start": 99, "end": 103, "id": 19}, {"text": "scintigraphy", "start": 104, "end": 116, "id": 20}, {"text": "(", "start": 117, "end": 118, "id": 21}, {"text": "a", "start": 118, "end": 119, "id": 22}, {"text": ")", "start": 119, "end": 120, "id": 23}, {"text": ":", "start": 120, "end": 121, "id": 24}, {"text": "increased", "start": 122, "end": 131, "id": 25}, {"text": "fixation", "start": 132, "end": 140, "id": 26}, {"text": "centered", "start": 141, "end": 149, "id": 27}, {"text": "on", "start": 150, "end": 152, "id": 28}, {"text": "the", "start": 153, "end": 156, "id": 29}, {"text": "extremity", "start": 157, "end": 166, "id": 30}, {"text": "of", "start": 167, "end": 169, "id": 31}, {"text": "the", "start": 170, "end": 173, "id": 32}, {"text": "first", "start": 174, "end": 179, "id": 33}, {"text": "digit", "start": 180, "end": 185, "id": 34}, {"text": ".", "start": 185, "end": 186, "id": 35}, {"text": "Standard", "start": 187, "end": 195, "id": 36}, {"text": "radiograph", "start": 196, "end": 206, "id": 37}, {"text": "(", "start": 207, "end": 208, "id": 38}, {"text": "b", "start": 208, "end": 209, "id": 39}, {"text": ")", "start": 209, "end": 210, "id": 40}, {"text": ":", "start": 210, "end": 211, "id": 41}, {"text": "demineralization", "start": 212, "end": 228, "id": 42}, {"text": "of", "start": 229, "end": 231, "id": 43}, {"text": "the", "start": 232, "end": 235, "id": 44}, {"text": "phalanx", "start": 236, "end": 243, "id": 45}, {"text": ",", "start": 243, "end": 244, "id": 46}, {"text": "thinning", "start": 245, "end": 253, "id": 47}, {"text": "of", "start": 254, "end": 256, "id": 48}, {"text": "the", "start": 257, "end": 260, "id": 49}, {"text": "external", "start": 261, "end": 269, "id": 50}, {"text": "border", "start": 270, "end": 276, "id": 51}, {"text": "of", "start": 277, "end": 279, "id": 52}, {"text": "the", "start": 280, "end": 283, "id": 53}, {"text": "proximal", "start": 284, "end": 292, "id": 54}, {"text": "cortex", "start": 293, "end": 299, "id": 55}, {"text": "of", "start": 300, "end": 302, "id": 56}, {"text": "the", "start": 303, "end": 306, "id": 57}, {"text": "first", "start": 307, "end": 312, "id": 58}, {"text": "pharynx", "start": 313, "end": 320, "id": 59}, {"text": "indicating", "start": 321, "end": 331, "id": 60}, {"text": "early", "start": 332, "end": 337, "id": 61}, {"text": "dactylitis", "start": 338, "end": 348, "id": 62}, {"text": ".", "start": 348, "end": 349, "id": 63}]}
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{"pdf_hash": "40e3e22ed7a28d203ccbc5e6e2e3949400655de2", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Transthoracic echocardiogram without and with definity contrast demonstrated absence of thrombus. A: Parasternal short axis of transthoracic echocardiogram; B: Apical 4-chamber of transthoracic echocardiogram; C: Apical 2-chamber of transthoracic echocardiogram; D: Parasternal short axis transthoracic echocardiogram with definity contrast; E: Apical 4-chamber transthoracic echocardiogram with definity contrast; F: Apical 2-chamber transthoracic echocardiogram with definity contrast. There is an inferior wall aneurysm (red star). 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{"pdf_hash": "34bd8a5aae092013a7d9a162b4098b6d8705d1b9", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2 Test results of a 60-year-old Hispanic female on Plaquenil for 6 years for treatment of dermatomyositis (maximum daily dose of 4.63 mg/kg/day and cumulative dose of 876 g, BCVA 20/20 \u00c0 1 ). (a) Microperimetry Polar 3 test grid superimposed on the scanning laser ophthalmoscope infrared image showing reduced mean retinal sensitivity (13.4 dB). Small white crosses indicate fixation. (b) Corresponding spectral-domain optical coherence tomography thickness at each of the 28 Polar 3 tested points shows no retinal thinning. (c)Automated 10-2 Humphrey visual field shows a normal pattern deviation. (d) Fundus autofluorescence shows no retinal pigment epithelium abnormalities. 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{"pdf_hash": "9d20b3e762ccc67ddee37ccfb8344d6e88b389dc", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3: Four years postoperative axial (a and b), sagittal (c and d), a coronal (e) T1\u2011weighted MR images with gadolinium demonstrating further slow growth of both lesions described in Figure 2", "width": 674, "height": 534, "subcaptions": {"a": [13, 14, 15, 16, 17, 18], "b": [20, 21, 22, 23, 24]}, "subfigures": [{"id": "37b7958e-6840-46a2-8a3e-decf9c1a50cc", "label": "a", "points": [[1.6, 3.2], [1.6, 252.4], [227.3, 252.4], [227.3, 3.2]], "color": "yellow"}, {"id": "00e915fd-a837-4875-8b3c-ce2806569a34", "label": "a", "points": [[231.6, 1.1], [231.6, 254.5], [455.2, 254.5], [455.2, 1.1]], "color": "cyan"}, {"id": "5f6fc945-07ae-45fc-b5cb-fc982d42ea88", "label": "b", "points": [[458.4, 2.1], [458.4, 254.5], [671.4, 254.5], [671.4, 2.1]], "color": "magenta"}, {"id": "baaab418-60dc-4433-8dcd-1078d69ee386", "label": "b", "points": [[108.1, 257.7], [108.1, 506.8], [335.9, 506.8], [335.9, 257.7]], "color": "springgreen"}, {"id": "f8656f24-1ce2-464d-9f3f-f9c67aee3930", "label": "c", "points": [[341.3, 257.7], [341.3, 504.7], [565.9, 504.7], [565.9, 257.7]], "color": "tomato"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Four", "start": 10, "end": 14, "id": 3}, {"text": "years", "start": 15, "end": 20, "id": 4}, {"text": "postoperative", "start": 21, "end": 34, "id": 5}, {"text": "axial", "start": 35, "end": 40, "id": 6}, {"text": "(", "start": 41, "end": 42, "id": 7}, {"text": "a", "start": 42, "end": 43, "id": 8}, {"text": "and", "start": 44, "end": 47, "id": 9}, {"text": "b", "start": 48, "end": 49, "id": 10}, {"text": ")", "start": 49, "end": 50, "id": 11}, {"text": ",", "start": 50, "end": 51, "id": 12}, {"text": "sagittal", "start": 52, "end": 60, "id": 13}, {"text": "(", "start": 61, "end": 62, "id": 14}, {"text": "c", "start": 62, "end": 63, "id": 15}, {"text": "and", "start": 64, "end": 67, "id": 16}, {"text": "d", "start": 68, "end": 69, "id": 17}, {"text": ")", "start": 69, "end": 70, "id": 18}, {"text": ",", "start": 70, "end": 71, "id": 19}, {"text": "a", "start": 72, "end": 73, "id": 20}, {"text": "coronal", "start": 74, "end": 81, "id": 21}, {"text": "(", "start": 82, "end": 83, "id": 22}, {"text": "e", "start": 83, "end": 84, "id": 23}, {"text": ")", "start": 84, "end": 85, "id": 24}, {"text": "T1\u2011weighted", "start": 86, "end": 97, "id": 25}, {"text": "MR", "start": 98, "end": 100, "id": 26}, {"text": "images", "start": 101, "end": 107, "id": 27}, {"text": "with", "start": 108, "end": 112, "id": 28}, {"text": "gadolinium", "start": 113, "end": 123, "id": 29}, {"text": "demonstrating", "start": 124, "end": 137, "id": 30}, {"text": "further", "start": 138, "end": 145, "id": 31}, {"text": "slow", "start": 146, "end": 150, "id": 32}, {"text": "growth", "start": 151, "end": 157, "id": 33}, {"text": "of", "start": 158, "end": 160, "id": 34}, {"text": "both", "start": 161, "end": 165, "id": 35}, {"text": "lesions", "start": 166, "end": 173, "id": 36}, {"text": "described", "start": 174, "end": 183, "id": 37}, {"text": "in", "start": 184, "end": 186, "id": 38}, {"text": "Figure", "start": 187, "end": 193, "id": 39}, {"text": "2", "start": 194, "end": 195, "id": 40}]}
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{"pdf_hash": "15eecbc40b76c2dcaa502f8791889f9ad0e05f7f", "fig_key": "Figure21", "fig_uri": "20-Figure21-1.png", "text": "Fig. 21 Chronic anaemia. Sagittal head CT (a) depicts widening of the diploic space (thick arrows). 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{"pdf_hash": "05f98b64ff028b99fbea0c241352fe1e2dbed977", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3: Follow-up MRI Cervical Spine with Contrast: Three month follow-up MRI (T1 and T2-weighted) of cervical spine demonstrating complete resolution of hematoma with moderate stenosis from pre-existing osteophyte complexes emanating from the vertebral bodies of C2-C4. (a) Follow-up Sagittal T2-Weighted MRI, (b) Followup Sagittal T1-Weighted MRI", "width": 676, "height": 702, "subcaptions": {"a": [58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "3027901d-cd1d-4a3b-ab50-32194f6f9526", "label": "a", "points": [[3.4, 21], [3.4, 347.8], [227.7, 347.8], [227.7, 21]], "color": "yellow"}, {"id": "91530780-52ea-4ae6-950d-c6c53c7ad73d", "label": "a", "points": [[229.8, 24.2], [229.8, 347.8], [453, 347.8], [453, 24.2]], "color": "cyan"}, {"id": "25ee8575-bbbe-4677-85cc-adcf8e50e565", "label": "a", "points": [[454.1, 21], [454.1, 340.3], [669.8, 340.3], [669.8, 21]], "color": "magenta"}, {"id": "9e98dc2b-e82a-4d60-b834-7916b36056eb", "label": "b", "points": [[3.4, 353.1], [3.4, 681], [217, 681], [217, 353.1]], "color": "springgreen"}, {"id": "20feb3ac-eb68-4b87-92ee-3b368b1a3d72", "label": "b", "points": [[217, 349.9], [217, 682.1], [454.1, 682.1], [454.1, 349.9]], "color": "tomato"}, {"id": "fd261940-ffc0-4781-9d74-ab17964b940d", "label": "b", "points": [[457.3, 345.7], [457.3, 681], [670.9, 681], [670.9, 345.7]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Follow", "start": 10, "end": 16, "id": 3}, {"text": "-", "start": 16, "end": 17, "id": 4}, {"text": "up", "start": 17, "end": 19, "id": 5}, {"text": "MRI", "start": 20, "end": 23, "id": 6}, {"text": "Cervical", "start": 24, "end": 32, "id": 7}, {"text": "Spine", "start": 33, "end": 38, "id": 8}, {"text": "with", "start": 39, "end": 43, "id": 9}, {"text": "Contrast", "start": 44, "end": 52, "id": 10}, {"text": ":", "start": 52, "end": 53, "id": 11}, {"text": "Three", "start": 54, "end": 59, "id": 12}, {"text": "month", "start": 60, "end": 65, "id": 13}, {"text": "follow", "start": 66, "end": 72, "id": 14}, {"text": "-", "start": 72, "end": 73, "id": 15}, {"text": "up", "start": 73, "end": 75, "id": 16}, {"text": "MRI", "start": 76, "end": 79, "id": 17}, {"text": "(", "start": 80, "end": 81, "id": 18}, {"text": "T1", "start": 81, "end": 83, "id": 19}, {"text": "and", "start": 84, "end": 87, "id": 20}, {"text": "T2-weighted", "start": 88, "end": 99, "id": 21}, {"text": ")", "start": 99, "end": 100, "id": 22}, {"text": "of", "start": 101, "end": 103, "id": 23}, {"text": "cervical", "start": 104, "end": 112, "id": 24}, {"text": "spine", "start": 113, "end": 118, "id": 25}, {"text": "demonstrating", "start": 119, "end": 132, "id": 26}, {"text": "complete", "start": 133, "end": 141, "id": 27}, {"text": "resolution", "start": 142, "end": 152, "id": 28}, {"text": "of", "start": 153, "end": 155, "id": 29}, {"text": "hematoma", "start": 156, "end": 164, "id": 30}, {"text": "with", "start": 165, "end": 169, "id": 31}, {"text": "moderate", "start": 170, "end": 178, "id": 32}, {"text": "stenosis", "start": 179, "end": 187, "id": 33}, {"text": "from", "start": 188, "end": 192, "id": 34}, {"text": "pre", "start": 193, "end": 196, "id": 35}, {"text": "-", "start": 196, "end": 197, "id": 36}, {"text": "existing", "start": 197, "end": 205, "id": 37}, {"text": "osteophyte", "start": 206, "end": 216, "id": 38}, {"text": "complexes", "start": 217, "end": 226, "id": 39}, {"text": "emanating", "start": 227, "end": 236, "id": 40}, {"text": "from", "start": 237, "end": 241, "id": 41}, {"text": "the", "start": 242, "end": 245, "id": 42}, {"text": "vertebral", "start": 246, "end": 255, "id": 43}, {"text": "bodies", "start": 256, "end": 262, "id": 44}, {"text": "of", "start": 263, "end": 265, "id": 45}, {"text": "C2-C4", "start": 266, "end": 271, "id": 46}, {"text": ".", "start": 271, "end": 272, "id": 47}, {"text": "(", "start": 273, "end": 274, "id": 48}, {"text": "a", "start": 274, "end": 275, "id": 49}, {"text": ")", "start": 275, "end": 276, "id": 50}, {"text": "Follow", "start": 277, "end": 283, "id": 51}, {"text": "-", "start": 283, "end": 284, "id": 52}, {"text": "up", "start": 284, "end": 286, "id": 53}, {"text": "Sagittal", "start": 287, "end": 295, "id": 54}, {"text": "T2-Weighted", "start": 296, "end": 307, "id": 55}, {"text": "MRI", "start": 308, "end": 311, "id": 56}, {"text": ",", "start": 311, "end": 312, "id": 57}, {"text": "(", "start": 313, "end": 314, "id": 58}, {"text": "b", "start": 314, "end": 315, "id": 59}, {"text": ")", "start": 315, "end": 316, "id": 60}, {"text": "Followup", "start": 317, "end": 325, "id": 61}, {"text": "Sagittal", "start": 326, "end": 334, "id": 62}, {"text": "T1-Weighted", "start": 335, "end": 346, "id": 63}, {"text": "MRI", "start": 347, "end": 350, "id": 64}]}
{"pdf_hash": "31d2f05908f3e855e56986572afd3930c9be24ed", "fig_key": "Figure2", "fig_uri": "8-Figure2-1.png", "text": "Fig. 2 This 49-year-old lady presented with a 6-week history of reduced vision in the left eye. Visual acuity at presentation was 6/12 in the affected eye, which also showed a chorioretinal scar from a past toxoplasmosis-related chorioretinitis. Fluoresceine angiography revealed a parafoveal spot of active leakage from early- (a) through mid- (b) to late-phase (c). Optical coherence tomography angiography (OCTA) confirmed the presence of a vascular network (d) between the retinal pigment epithelium and Bruch\u2019s membrane (e). 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{"pdf_hash": "8396bb8706cfa237d9fbbffe339c348f450acabc", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. (A) Arthroscopic view of a stifle documenting the measurement of the distance between the medial femoral condyle (mFC) and the tibial articular cartilage. Visualization was scored by using the tip of the probe. (B and C) Digital imaging and a computer software program were used to trace the entire surface of the articular cartilage, the area of damaged articular cartilage (which was stained with India ink), and to calculate the percentage area of cartilage damage for both the femoral and tibial surfaces. mM, medial meniscus; MP, meniscal probe; pTAC, proximal tibial articular cartilage.", "width": 660, "height": 292, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98]}, "subfigures": [{"id": "4fc573d5-0405-4197-a93d-d694c08c735a", "label": "a", "points": [[4.1, 0.2], [4.1, 263], [218.9, 263], [218.9, 0.2]], "color": "yellow"}, {"id": 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542, "id": 105}, {"text": "meniscal", "start": 543, "end": 551, "id": 106}, {"text": "probe", "start": 552, "end": 557, "id": 107}, {"text": ";", "start": 557, "end": 558, "id": 108}, {"text": "pTAC", "start": 559, "end": 563, "id": 109}, {"text": ",", "start": 563, "end": 564, "id": 110}, {"text": "proximal", "start": 565, "end": 573, "id": 111}, {"text": "tibial", "start": 574, "end": 580, "id": 112}, {"text": "articular", "start": 581, "end": 590, "id": 113}, {"text": "cartilage", "start": 591, "end": 600, "id": 114}, {"text": ".", "start": 600, "end": 601, "id": 115}]}
{"pdf_hash": "833b00a4a9328f40f0b773ad8ab039c08e77778d", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig. 3 Assignment of tissue values. ROIs were delineated in a clinical MR (a). Similar contrast values were imposed to the tissues in the attenuation image generated with the XCAT phantom. Panes b, c and d represent the sagittal, transaxial and axial views of the XCAT phantom, respectively, after conversion to MR-like contrast values", "width": 660, "height": 1108, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [64, 65, 37, 38, 43, 44, 45, 50, 51, 52, 53, 54, 58, 59, 60, 61, 62, 63], "c": [64, 65, 37, 40, 43, 44, 47, 50, 51, 52, 53, 54, 58, 59, 60, 61, 62, 63], "d": [64, 65, 37, 42, 43, 44, 49, 50, 51, 52, 53, 54, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "d1f4741c-a187-493a-bcf3-17d9acbbdf43", "label": "a", "points": [[32.2, 22.1], [32.2, 579.9], [629.7, 579.9], [629.7, 22.1]], "color": "yellow"}, {"id": "41ef949d-8025-432b-94ac-19cbed545805", "label": "b", "points": [[36.4, 596.6], [36.4, 963.6], [626.5, 963.6], [626.5, 596.6]], "color": "cyan"}, {"id": "ca95ee25-12f9-472b-bf27-84fe7901a93e", "label": "c", "points": [[32.2, 982.4], [32.2, 1080.4], [234.5, 1080.4], [234.5, 982.4]], "color": "magenta"}, {"id": "a9c64adb-5e9c-459a-b55c-8ba477074137", "label": "d", "points": [[263.7, 979.3], [263.7, 1077.3], [628.6, 1077.3], [628.6, 979.3]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Assignment", "start": 7, "end": 17, "id": 3}, {"text": "of", "start": 18, "end": 20, "id": 4}, {"text": "tissue", "start": 21, "end": 27, "id": 5}, {"text": "values", "start": 28, "end": 34, "id": 6}, {"text": ".", "start": 34, "end": 35, "id": 7}, {"text": "ROIs", "start": 36, "end": 40, "id": 8}, {"text": "were", "start": 41, "end": 45, "id": 9}, {"text": "delineated", "start": 46, "end": 56, "id": 10}, {"text": "in", "start": 57, "end": 59, "id": 11}, {"text": "a", "start": 60, "end": 61, "id": 12}, {"text": "clinical", "start": 62, "end": 70, "id": 13}, {"text": "MR", "start": 71, "end": 73, "id": 14}, {"text": "(", "start": 74, "end": 75, "id": 15}, {"text": "a", "start": 75, "end": 76, "id": 16}, {"text": ")", "start": 76, "end": 77, "id": 17}, {"text": ".", "start": 77, "end": 78, "id": 18}, {"text": "Similar", "start": 79, "end": 86, "id": 19}, {"text": "contrast", "start": 87, "end": 95, "id": 20}, {"text": "values", "start": 96, "end": 102, "id": 21}, {"text": "were", "start": 103, "end": 107, "id": 22}, {"text": "imposed", "start": 108, "end": 115, "id": 23}, {"text": "to", "start": 116, "end": 118, "id": 24}, {"text": "the", "start": 119, "end": 122, "id": 25}, {"text": "tissues", "start": 123, "end": 130, "id": 26}, {"text": "in", "start": 131, "end": 133, "id": 27}, {"text": "the", "start": 134, "end": 137, "id": 28}, {"text": "attenuation", "start": 138, "end": 149, "id": 29}, {"text": "image", "start": 150, "end": 155, "id": 30}, {"text": "generated", "start": 156, "end": 165, "id": 31}, {"text": "with", "start": 166, "end": 170, "id": 32}, {"text": "the", "start": 171, "end": 174, "id": 33}, {"text": "XCAT", "start": 175, "end": 179, "id": 34}, {"text": "phantom", "start": 180, "end": 187, "id": 35}, {"text": ".", "start": 187, "end": 188, "id": 36}, {"text": "Panes", "start": 189, "end": 194, "id": 37}, {"text": "b", "start": 195, "end": 196, "id": 38}, {"text": ",", "start": 196, "end": 197, "id": 39}, {"text": "c", "start": 198, "end": 199, "id": 40}, {"text": "and", "start": 200, "end": 203, "id": 41}, {"text": "d", "start": 204, "end": 205, "id": 42}, {"text": "represent", "start": 206, "end": 215, "id": 43}, {"text": "the", "start": 216, "end": 219, "id": 44}, {"text": "sagittal", "start": 220, "end": 228, "id": 45}, {"text": ",", "start": 228, "end": 229, "id": 46}, {"text": "transaxial", "start": 230, "end": 240, "id": 47}, {"text": "and", "start": 241, "end": 244, "id": 48}, {"text": "axial", "start": 245, "end": 250, "id": 49}, {"text": "views", "start": 251, "end": 256, "id": 50}, {"text": "of", "start": 257, "end": 259, "id": 51}, {"text": "the", "start": 260, "end": 263, "id": 52}, {"text": "XCAT", "start": 264, "end": 268, "id": 53}, {"text": "phantom", "start": 269, "end": 276, "id": 54}, {"text": ",", "start": 276, "end": 277, "id": 55}, {"text": "respectively", "start": 278, "end": 290, "id": 56}, {"text": ",", "start": 290, "end": 291, "id": 57}, {"text": "after", "start": 292, "end": 297, "id": 58}, {"text": "conversion", "start": 298, "end": 308, "id": 59}, {"text": "to", "start": 309, "end": 311, "id": 60}, {"text": "MR", "start": 312, "end": 314, "id": 61}, {"text": "-", "start": 314, "end": 315, "id": 62}, {"text": "like", "start": 315, "end": 319, "id": 63}, {"text": "contrast", "start": 320, "end": 328, "id": 64}, {"text": "values", "start": 329, "end": 335, "id": 65}]}
{"pdf_hash": "cc6ece4bdf09ffd88126a306cf95f4af8d337c0d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. (A) Photomicrographs showing a lesion composed of nodules of hyaline cartilage with overlying flattened synovial lining (arrow) (H&E, \u00d750). (B) The chondrocytes are clustered and exhibit nuclear atypia with binucleation and hyperchromatic nuclei (H&E, \u00d7100). (C) Histological features are characteristic of synovial chondromatosis (arrowhead) (H&E, \u00d7200).", "width": 1060, "height": 384, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71]}, "subfigures": [{"id": "2f7808f8-c683-4fda-9136-79bcee6f045b", "label": "a", "points": [[2.6, 3.1], [2.6, 348], [344.2, 348], [344.2, 3.1]], "color": "yellow"}, {"id": "801f6ae7-dc87-4d63-acf7-5999a6b975d8", "label": "b", "points": [[364.3, 4.7], [364.3, 354.7], [702.5, 354.7], [702.5, 4.7]], "color": "cyan"}, {"id": "4ec16d39-3b14-40f6-9fc6-0b19cacf8340", "label": "c", "points": [[717.6, -0.3], [717.6, 354.7], [1052.5, 354.7], [1052.5, -0.3]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Photomicrographs", "start": 12, "end": 28, "id": 7}, {"text": "showing", "start": 29, "end": 36, "id": 8}, {"text": "a", "start": 37, "end": 38, "id": 9}, {"text": "lesion", "start": 39, "end": 45, "id": 10}, {"text": "composed", "start": 46, "end": 54, "id": 11}, {"text": "of", "start": 55, "end": 57, "id": 12}, {"text": "nodules", "start": 58, "end": 65, "id": 13}, {"text": "of", "start": 66, "end": 68, "id": 14}, {"text": "hyaline", "start": 69, "end": 76, "id": 15}, {"text": "cartilage", "start": 77, "end": 86, "id": 16}, {"text": "with", "start": 87, "end": 91, "id": 17}, {"text": "overlying", "start": 92, "end": 101, "id": 18}, {"text": "flattened", "start": 102, "end": 111, "id": 19}, {"text": "synovial", "start": 112, "end": 120, "id": 20}, {"text": "lining", "start": 121, "end": 127, "id": 21}, {"text": "(", "start": 128, "end": 129, "id": 22}, {"text": "arrow", "start": 129, "end": 134, "id": 23}, {"text": ")", "start": 134, "end": 135, "id": 24}, {"text": "(", "start": 136, "end": 137, "id": 25}, {"text": "H&E", "start": 137, "end": 140, "id": 26}, {"text": ",", "start": 140, "end": 141, "id": 27}, {"text": "\u00d750", "start": 142, "end": 145, "id": 28}, {"text": ")", "start": 145, "end": 146, "id": 29}, {"text": ".", "start": 146, "end": 147, "id": 30}, {"text": "(", "start": 148, "end": 149, "id": 31}, {"text": "B", "start": 149, "end": 150, "id": 32}, {"text": ")", "start": 150, "end": 151, "id": 33}, {"text": "The", "start": 152, "end": 155, "id": 34}, {"text": "chondrocytes", "start": 156, "end": 168, "id": 35}, {"text": "are", "start": 169, "end": 172, "id": 36}, {"text": "clustered", "start": 173, "end": 182, "id": 37}, {"text": "and", "start": 183, "end": 186, "id": 38}, {"text": "exhibit", "start": 187, "end": 194, "id": 39}, {"text": "nuclear", "start": 195, "end": 202, "id": 40}, {"text": "atypia", "start": 203, "end": 209, "id": 41}, {"text": "with", "start": 210, "end": 214, "id": 42}, {"text": "binucleation", "start": 215, "end": 227, "id": 43}, {"text": "and", "start": 228, "end": 231, "id": 44}, {"text": "hyperchromatic", "start": 232, "end": 246, "id": 45}, {"text": "nuclei", "start": 247, "end": 253, "id": 46}, {"text": "(", "start": 254, "end": 255, "id": 47}, {"text": "H&E", "start": 255, "end": 258, "id": 48}, {"text": ",", "start": 258, "end": 259, "id": 49}, {"text": "\u00d7100", "start": 260, "end": 264, "id": 50}, {"text": ")", "start": 264, "end": 265, "id": 51}, {"text": ".", "start": 265, "end": 266, "id": 52}, {"text": "(", "start": 267, "end": 268, "id": 53}, {"text": "C", "start": 268, "end": 269, "id": 54}, {"text": ")", "start": 269, "end": 270, "id": 55}, {"text": "Histological", "start": 271, "end": 283, "id": 56}, {"text": "features", "start": 284, "end": 292, "id": 57}, {"text": "are", "start": 293, "end": 296, "id": 58}, {"text": "characteristic", "start": 297, "end": 311, "id": 59}, {"text": "of", "start": 312, "end": 314, "id": 60}, {"text": "synovial", "start": 315, "end": 323, "id": 61}, {"text": "chondromatosis", "start": 324, "end": 338, "id": 62}, {"text": "(", "start": 339, "end": 340, "id": 63}, {"text": "arrowhead", "start": 340, "end": 349, "id": 64}, {"text": ")", "start": 349, "end": 350, "id": 65}, {"text": "(", "start": 351, "end": 352, "id": 66}, {"text": "H&E", "start": 352, "end": 355, "id": 67}, {"text": ",", "start": 355, "end": 356, "id": 68}, {"text": "\u00d7200", "start": 357, "end": 361, "id": 69}, {"text": ")", "start": 361, "end": 362, "id": 70}, {"text": ".", "start": 362, "end": 363, "id": 71}]}
{"pdf_hash": "0f1dd80d119ef90b9fd38f89d63fd8263a04e6f1", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4. Transmission electron microscopy of vehicle-treated and extract-treated Jurkat cells. Treatment with D. seychellarum extract induces morphological changes characteristic of apoptosis. (A) Vehicle-treated cells show typical cell morphology with (B) intact mitochondria and, (C) intact nuclear membrane bilayer (arrow). (D) Cells treated with 250 \u03bcg/mL of extract for 18 hr show an increase in electron rich chromatin condensation compared to vehicle treated cells (arrowhead), (E) swollen mitochondria with disrupted cristae, and (F) a loss of the nuclear membrane bilayer. 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{"pdf_hash": "c02cc0b2d97ff0dc396590793356ffd976ba731f", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1 Color Doppler ultrasound and anterior segment photograph of a 36-month-old child with congenital cataract and anterior PHPV in Case 4 A: A retrolental vascular fibrous membrane is found using color Doppler ultrasound; B: The remnant fetal vessels that integrate with the anterior and posterior capsule and iris have formed the retrolental vascular fibrous membrane; C: Some neovascularization integrated with the anterior and posterior capsule or iris is being cauterized using underwater electric coagulation; D: Continuous curvilinear capsulorhexis of 6.0 mm and 4.0 mm respectively, have been made in the anterior and posterior capsule; E: A posterior chamber IOL has been implanted into the double capsulorhexis capsular bag; F: The anterior segment photograph of the slip-lamp after implantation of the IOL, taken 90d after the surgery.", "width": 1092, "height": 704, 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{"pdf_hash": "cde11a44116a8a5ee4825734394fc1dc5f55e0b8", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. (A), The lack of hair (alopecia) in the left parieto-temporal area; (B), The lack of hair (alopecia) in the right parietotemporal area, the head alongated in the vertical axis and the low-set ears; (C), The head elongated in the vertical axis and deformed corpus callosum - CC (MRI, sagittal plane). CC deformation is expressed in arching of the middle part of the CC.", "width": 1298, "height": 424, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90]}, "subfigures": [{"id": "a83adf23-1c0b-4e2c-bde9-47439b3badd8", "label": "a", "points": [[10.8, 1.8], [10.8, 416], [429.2, 416], [429.2, 1.8]], "color": "yellow"}, {"id": "3bb3b5dd-4374-4383-b633-24fd148c3e25", "label": "b", "points": [[441.5, 7.9], [441.5, 420.1], [859.8, 420.1], [859.8, 7.9]], "color": "cyan"}, {"id": "e9a91272-f122-4824-a052-41e5fd9892ee", "label": "c", "points": [[882.4, 1.8], [882.4, 420.1], [1296.6, 420.1], [1296.6, 1.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 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{"pdf_hash": "1cf8df1a963f2383bcc6b05eab6659affb37be89", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5. Expression pattern of PPEF, as revealed by in situ hybridization in a 13.5 day old mouse embryo. (A) Autoradiography of a sagittal section shows expression restricted to the trigeminal ganglion and the dorsal root ganglia. Sagittal sections through the head show PPEF expression in the trigeminal ganglion ( B). A strong hybridization signal is present in the dorsal root ganglia, as displayed in a sagittal section (C) and in a transverse section (D). Ppef positive signal is also present in the inner ear (E) and in a group of neurons located at the pons/midbrain junction (arrow in F). 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{"pdf_hash": "e46a8c3f51a216de8d3258aedaf8bba18cf731e9", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Abdominal CT scan following administration of oral contrast. (A) The adrenal mass was enhanced by oral contrast material shortly after staining the stomach and duodenum, and a bubble/shadow was observed within the mass (arrow). (B) Another CT image showed a connection between the adrenal mass and the stomach (arrow). (C) Transverse view following administration of oral contrast agent shortly after staining the stomach and duodenum. 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{"pdf_hash": "f666bd581790d58094d9127b9afbff3688bae1b0", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Insula activation in migraine. (A) Resting state: Group comparison maps showing higher default mode network connectivity in migraine versus healthy controls in the right and left anterior insula respectively. Adapted from (Xue and others 2012) with permission. (B) Chronicity: Functional connections with affective pain regions have been shown to differ between patients with chronic migraine (CM) and healthy controls. The connectivity strength of the anterior insula was correlated with the number of years of CM ((from Schwedt and others 2013) with permission). (C) Interictal noxious heat: fMRI contrast analysis of high-frequency versus low-frequency migraineurs in response to a +1\u00b0C pain threshold shows significant differences in the contralateral anterior insula in addition and bilateral inferior circular insula. These findings were co-localized with observed structural differences in the inferior circular insula (shown in green). Adapted from (Maleki and others 2012a) with permission. (D) Sex differences: Maps illustrating sex differences between male and female migraineurs in the insula. (Left) Males have higher fMRI activation in response to painful heat in the insula compared with females; whereas (right) insula cortical thickness is increased in females compared with males. Adapted from (Maleki and others 2012b) with permission. (E) Ictal state: PET measures of spontaneous migraine show right insula activation. Adapted from Afridi and others (2005a) with permission. (F) Salience network: fMRI resting state functional connectivity using the left anterior insula (aINS) as a seed region. Teal represents resting state functional connectivity for healthy controls and purple for migraine subjects. Light violet represents the areas showing overlap. Shows connectivity patterns consistent with the salience network (SN). Results indicate an increased connection to the SN in migraine subjects. 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{"pdf_hash": "c003e1cad9c5e7d00e060e7b728fd39ab24e0112", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Retained deciduous teeth and multiple impacted permanent teeth in cleidocranial displasia patient. (a) Intraoral photograph pre-treatment. (b) Periapical film of retained primary maxillary incisors and their successors. (c) Unerupted maxillary central incisors covered by dental follicle were surgically exposed. 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{"pdf_hash": "3d200286e87a4fc17a142652bb71020dc40b9b82", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIGURE 1 Human sperm treated with alkaline thiogycolate and followed by phase-contrast microscopy . Fig . 1 a shows an early stage of treatment . The sperm head membranes are relatively intact. Fig. 1 b, the head membranes have ruptured and the exposed nucleus begins to expand . A portion of the acrosomal cap is attached to the nucleus tip . Fig . 1 c, the nucleus becomes diffuse with the acrosomal cap still adhering to the tip. Fig . 1 d, the final stage of nuclear exposure showing the head cap expelled and the nucleus in an expanded state. Scale marker, 5 ,u. 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{"pdf_hash": "c0f01893a1f87067cf1ebf9ad94632754a6b83aa", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Plain abdominal computed tomography scan. a. the mass in the sigmoid colon cancer (arrow) and dilated small bowel (arrowhead), b. dilation of the colon proximal to the tumor (arrow).", "width": 1032, "height": 442, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "e08c7c4e-5cda-454e-bfc3-8e6b5f4b2291", "label": "a", "points": [[37.3, 0.3], [37.3, 365.5], [559.1, 365.5], [559.1, 0.3]], "color": "yellow"}, {"id": "6be9269b-fd7c-4ed5-bf9f-100ccacbe5f4", "label": "b", "points": [[1028.6, 5.2], [1028.6, 365.5], [580.3, 365.5], [580.3, 5.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Plain", "start": 8, "end": 13, "id": 4}, {"text": "abdominal", "start": 14, "end": 23, "id": 5}, {"text": "computed", "start": 24, "end": 32, "id": 6}, {"text": "tomography", "start": 33, "end": 43, "id": 7}, {"text": "scan", "start": 44, "end": 48, "id": 8}, {"text": ".", "start": 48, "end": 49, "id": 9}, {"text": "a.", "start": 50, "end": 52, "id": 10}, {"text": "the", "start": 53, "end": 56, "id": 11}, {"text": "mass", "start": 57, "end": 61, "id": 12}, {"text": "in", "start": 62, "end": 64, "id": 13}, {"text": "the", "start": 65, "end": 68, "id": 14}, {"text": "sigmoid", "start": 69, "end": 76, "id": 15}, {"text": "colon", "start": 77, "end": 82, "id": 16}, {"text": "cancer", "start": 83, "end": 89, "id": 17}, {"text": "(", "start": 90, "end": 91, "id": 18}, {"text": "arrow", "start": 91, "end": 96, "id": 19}, {"text": ")", "start": 96, "end": 97, "id": 20}, {"text": "and", "start": 98, "end": 101, "id": 21}, {"text": "dilated", "start": 102, "end": 109, "id": 22}, {"text": "small", "start": 110, "end": 115, "id": 23}, {"text": "bowel", "start": 116, "end": 121, "id": 24}, {"text": "(", "start": 122, "end": 123, "id": 25}, {"text": "arrowhead", "start": 123, "end": 132, "id": 26}, {"text": ")", "start": 132, "end": 133, "id": 27}, {"text": ",", "start": 133, "end": 134, "id": 28}, {"text": "b.", "start": 135, "end": 137, "id": 29}, {"text": "dilation", "start": 138, "end": 146, "id": 30}, {"text": "of", "start": 147, "end": 149, "id": 31}, {"text": "the", "start": 150, "end": 153, "id": 32}, {"text": "colon", "start": 154, "end": 159, "id": 33}, {"text": "proximal", "start": 160, "end": 168, "id": 34}, {"text": "to", "start": 169, "end": 171, "id": 35}, {"text": "the", "start": 172, "end": 175, "id": 36}, {"text": "tumor", "start": 176, "end": 181, "id": 37}, {"text": "(", "start": 182, "end": 183, "id": 38}, {"text": "arrow", "start": 183, "end": 188, "id": 39}, {"text": ")", "start": 188, "end": 189, "id": 40}, {"text": ".", "start": 189, "end": 190, "id": 41}]}
{"pdf_hash": "54cf2a0f830198498fd822c92c077afb571e184d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. The gametosome plays a critical role in spindle orientation. (A) Timelapse imaging of mCherry\u2013\u03b1-tubulin during the first division of the gametophore initial. Images were recorded every 15 s. Time 0 corresponds to the timing of NEBD. MTs emanated from the gametosome penetrate into the nucleus upon NEBD. Subsequent MT amplification and bipolarization leads to metaphase spindle formation (300 s). (B) Time-lapse imaging of mCherry\u2013 \u03b1-tubulin in a cell transiently treated with oryzalin. Before the first division in the gametophore initial, cells were treated with 20 \u03bcM oryzalin (\u221222 min), which destabilized the gametosome. Oryzalin was washed out upon NEBD (time 0), and images were recorded every 15 s. MTs were nucleated in a", "width": 650, "height": 1598, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75], "b": [0]}, "subfigures": [{"id": "74a1f3e9-8c1b-4715-b079-74c0733354bd", "label": "a", "points": [[8.2, 39], [8.2, 244.4], [635.6, 244.4], [635.6, 39]], "color": "yellow"}, {"id": "a5ab3106-6e68-4c63-aff3-333dc2cc53b6", "label": "b", "points": [[4.1, 335.8], [4.1, 540.1], [642.8, 540.1], [642.8, 335.8]], "color": "cyan"}, {"id": "1b91efaf-c1fd-462b-98ff-70c61dc85050", "label": "b", "points": [[4.1, 589.4], [4.1, 793.8], [635.6, 793.8], [635.6, 589.4]], "color": "magenta"}, {"id": "6b3d781e-1d2f-4493-ba7c-245fc2345bc6", "label": "b", "points": [[5.1, 844.1], [5.1, 1049.4], [640.8, 1049.4], [640.8, 844.1]], "color": "springgreen"}, {"id": 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{"pdf_hash": "95ae2c2c1c0ea18c22269305716bce7aac7ffc49", "fig_key": "Figure7", "fig_uri": "8-Figure7-1.png", "text": "Fig. 7 Spondylosis in the upper lumbar spine (35-year-old male with back pain). Plain radiography of the lumbar spine: a AP view, b lateral view, c right posterior oblique view, d left posterior oblique view. a A defect runs obliquely below the pedicle (arrow). The spinous process at L2 is slightly deviated (arrow head). 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{"pdf_hash": "29fd4c5eafc3a60d9a17b8b03407fb156e911e70", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 (a) A radiograph and (b) 3-dimensional computed tomographic scans showing an expansile lytic lesion in the right femorotrochanteric region with a patchy area of ground glass haze in the upper metadiaphyseal and femoral neck. The severe varus deformity and retroversion of the femoral neck and head is seen in the axial view.", "width": 1352, "height": 406, "subcaptions": {"a": [2, 3, 4, 5, 6, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "c": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "540c18a4-af61-41cc-9b09-43d1ba0bb953", "label": "a", "points": [[2.8, 1.9], [2.8, 399.1], [299.7, 399.1], [299.7, 1.9]], "color": "yellow"}, {"id": "be6125b2-fdb1-48c4-8934-cf2170eabfc5", "label": "b", "points": [[316.7, 4], [316.7, 401.3], [810.1, 401.3], [810.1, 4]], "color": "cyan"}, {"id": "968858bd-ed3c-4e49-a0ba-dc92eed09b90", "label": "c", "points": [[816.6, 1.9], [816.6, 401.3], [1350.5, 401.3], [1350.5, 1.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "A", "start": 13, "end": 14, "id": 5}, {"text": "radiograph", "start": 15, "end": 25, "id": 6}, {"text": "and", "start": 26, "end": 29, "id": 7}, {"text": "(", "start": 30, "end": 31, "id": 8}, {"text": "b", "start": 31, "end": 32, "id": 9}, {"text": ")", "start": 32, "end": 33, "id": 10}, {"text": "3-dimensional", "start": 34, "end": 47, "id": 11}, {"text": "computed", "start": 48, "end": 56, "id": 12}, {"text": "tomographic", "start": 57, "end": 68, "id": 13}, {"text": "scans", "start": 69, "end": 74, "id": 14}, {"text": "showing", "start": 75, "end": 82, "id": 15}, {"text": "an", "start": 83, "end": 85, "id": 16}, {"text": "expansile", "start": 86, "end": 95, "id": 17}, {"text": "lytic", "start": 96, "end": 101, "id": 18}, {"text": "lesion", "start": 102, "end": 108, "id": 19}, {"text": "in", "start": 109, "end": 111, "id": 20}, {"text": "the", "start": 112, "end": 115, "id": 21}, {"text": "right", "start": 116, "end": 121, "id": 22}, {"text": "femorotrochanteric", "start": 122, "end": 140, "id": 23}, {"text": "region", "start": 141, "end": 147, "id": 24}, {"text": "with", "start": 148, "end": 152, "id": 25}, {"text": "a", "start": 153, "end": 154, "id": 26}, {"text": "patchy", "start": 155, "end": 161, "id": 27}, {"text": "area", "start": 162, "end": 166, "id": 28}, {"text": "of", "start": 167, "end": 169, "id": 29}, {"text": "ground", "start": 170, "end": 176, "id": 30}, {"text": "glass", "start": 177, "end": 182, "id": 31}, {"text": "haze", "start": 183, "end": 187, "id": 32}, {"text": "in", "start": 188, "end": 190, "id": 33}, {"text": "the", "start": 191, "end": 194, "id": 34}, {"text": "upper", "start": 195, "end": 200, "id": 35}, {"text": "metadiaphyseal", "start": 201, "end": 215, "id": 36}, {"text": "and", "start": 216, "end": 219, "id": 37}, {"text": "femoral", "start": 220, "end": 227, "id": 38}, {"text": "neck", "start": 228, "end": 232, "id": 39}, {"text": ".", "start": 232, "end": 233, "id": 40}, {"text": "The", "start": 234, "end": 237, "id": 41}, {"text": "severe", "start": 238, "end": 244, "id": 42}, {"text": "varus", "start": 245, "end": 250, "id": 43}, {"text": "deformity", "start": 251, "end": 260, "id": 44}, {"text": "and", "start": 261, "end": 264, "id": 45}, {"text": "retroversion", "start": 265, "end": 277, "id": 46}, {"text": "of", "start": 278, "end": 280, "id": 47}, {"text": "the", "start": 281, "end": 284, "id": 48}, {"text": "femoral", "start": 285, "end": 292, "id": 49}, {"text": "neck", "start": 293, "end": 297, "id": 50}, {"text": "and", "start": 298, "end": 301, "id": 51}, {"text": "head", "start": 302, "end": 306, "id": 52}, {"text": "is", "start": 307, "end": 309, "id": 53}, {"text": "seen", "start": 310, "end": 314, "id": 54}, {"text": "in", "start": 315, "end": 317, "id": 55}, {"text": "the", "start": 318, "end": 321, "id": 56}, {"text": "axial", "start": 322, "end": 327, "id": 57}, {"text": "view", "start": 328, "end": 332, "id": 58}, {"text": ".", "start": 332, "end": 333, "id": 59}]}
{"pdf_hash": "09154974fdfa9c393f515bbc1a781117369416dc", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig 5. (A) With the patient placed in a supine position, the right knee at 30 flexion, and at neutral rotation, the medial collateral ligament (dashed white arrows) and the prospective site for the tibial anchor (solid white arrow) are identified. (NOTE. The green line is the midline function on the ultrasound machine. The green dot corresponds to the orientation of the ultrasound transducer.) (B) With the patient placed in a supine position, the right knee at 30 flexion, and at neutral rotation, the spinal needle (solid black arrow) is seen being placed at the site for the tibial anchor from an exterior view, corresponding with the ultrasound view. 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{"pdf_hash": "a7fae6766eccc04bdc814856283a388785e747bc", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Dcx KO CA3 layers show heterogeneous and disorganized cells compared to WT. Electron micrographs of the hippocampus from WT (A\u2013B) and KO mice (C\u2013E). (A) In WT, the broad layer of pyramidal neurons (delimited by dashed black lines) shows a more regular arrangement of adjacent columns of neurons (marked by circles). A layer bordering the stratum oriens (SO) displays neurons with occasional oval elongated shaped nuclei. All nuclei are surrounded by a light cytoplasm. (B) High magnification of pyramidal neurons displaying rounded or oval nuclei, with a homogeneous aspect of the nuclear membrane. (C) In the KO, the SPE bounds the SO (lower dashed black line) and the SPI is limited by the stratum radiatum (SR) (upper dashed black line). In both the SPE and SPI layers two types of cells are shown. One exhibits a clear cytoplasm and large nuclei (black asterisks) with round, elongated or lobulated shapes, enclosing light chromatin with peripherally located nucleoli, similar in aspect to the neuronal chromatin observed in WT. The second type of cell (white asterisks) has a darker cytoplasm, occasional tapered processes and encloses nuclei with dense chromatin. They are intermingled and often closely juxtaposed with neuronal-like cells. (D) In the SPI, two types of cells are shown, pyramidal neuronal-like cells with a clear cytoplasm and peripheral nucleoli (black asterisk) and a second cell type with a darker cytoplasm whose nucleoli are rarely peripheral (white asterisk). (E) In the SPE similar cell types with light (black asterisk) and dark cytoplasm (white asterisks) are also identified. Arrows in D and E indicate the irregular shape of the nuclear membrane. 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{"pdf_hash": "a1b4026d06d1111db38e031241f8221d6a622555", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. Coronal thionin-stained sections located immediately caudal to the fomix transections in cases FXI and FX2. A similar level is shown in a third animal (C), in which the lesion unilaterally involved the septal nuclei but did not transect the fomix. SmaN arrows are placed above the fomix approximately 5 mm lateral to the midline in each case. Note that there is marked shrinkage and gliosis of the fomix in the top 2 panels. Scale bar, 1 mm.", "width": 1308, "height": 1738, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 20, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 19, 20, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84], "c": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "d0be58a0-06cc-4afb-b646-2255a6ed3161", "label": "a", "points": [[23.3, 20.4], [23.3, 574.1], [1279.6, 574.1], [1279.6, 20.4]], "color": "yellow"}, {"id": "9e7f0934-fd3a-4141-95d7-d8062244b876", "label": "b", "points": [[29.5, 586.5], [29.5, 1144.4], [1281.7, 1144.4], [1281.7, 586.5]], "color": "cyan"}, {"id": "a9a73904-87ff-4551-8a50-6337f30bf066", "label": "c", "points": [[21.3, 1160.9], [21.3, 1706.4], [1279.6, 1706.4], [1279.6, 1160.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, 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{"pdf_hash": "3371b6c35cb1b08886da9c92f039a9e8f20b1309", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Figure 6. a\u2013d. Intraventricular cavernoma as an incidental finding in an 18-year-old male patient. Axial CT scan (a) shows an oval, wellcircumscribed, hyperdense mass lesion in the left frontal horn of lateral ventricle (arrow). The lesion shows heterogeneous hyperintense and hypointense signals on axial T1-weighted MR image (b, arrow). There is a typical peripheral hemosiderin rim of low signal intensity on coronal T2-weighted MR image (c, arrow). 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{"pdf_hash": "ef86d2bc0d42f31946a7d56bb2a152eb0f0031af", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 Findings on imaging. Computed tomography (CT) of the patient\u2019s abdomen (A\u2014abdominal view, and B\u2014liver view) revealed a prominent Riedel lobe of the liver, with no evidence of obstruction, thrombosis, or malignancy. Mild changes of sigmoid diverticulosis were seen, with no evidence of acute diverticulitis. A repeat CT revealed mild ascites localized to the right upper quadrant, and the liver edge appeared to have a slightly nodular contour, a non-specific finding in this particular case, but which in general may suggest cirrhosis. Abdominal ultrasound (C, D) revealed a heterogeneous echotexture of the liver with regions of increased echogenicity in the right lobe, a non-specific finding which may be seen in hepatitis", "width": 1340, "height": 1002, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106], "b": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 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{"pdf_hash": "1951b85d81ede3684754f25492a3922ce4f5ffbe", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Flair-weighted axial section (A), T2-weighted sagittal section (B) and T1-weighted coronal section (C) of cranial MR images show diffuse cerebral, cerebellar atrophy and ventricular enlargement secondary to atrophy.", "width": 1340, "height": 470, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11], "b": [12, 13, 14, 15, 16, 17], "c": [19, 20, 21, 22, 23, 24]}, "subfigures": [{"id": "9e5db96e-386e-496e-844b-8282c51301e4", "label": "a", "points": [[1.1, -0.3], [1.1, 399.7], [377.9, 399.7], [377.9, -0.3]], "color": "yellow"}, {"id": "bfce3bae-23b9-4c0d-b729-d175f7fd9796", "label": "b", "points": [[394.9, 1.8], [394.9, 399.7], [907.2, 399.7], [907.2, 1.8]], "color": "cyan"}, {"id": "c42eee3c-8d6a-4968-a444-d435ac06dfa1", "label": "c", "points": [[930.5, 1.8], [930.5, 404], [1332.7, 404], [1332.7, 1.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Flair", "start": 10, "end": 15, "id": 3}, {"text": "-", "start": 15, "end": 16, "id": 4}, {"text": "weighted", "start": 16, "end": 24, "id": 5}, {"text": "axial", "start": 25, "end": 30, "id": 6}, {"text": "section", "start": 31, "end": 38, "id": 7}, {"text": "(", "start": 39, "end": 40, "id": 8}, {"text": "A", "start": 40, "end": 41, "id": 9}, {"text": ")", "start": 41, "end": 42, "id": 10}, {"text": ",", "start": 42, "end": 43, "id": 11}, {"text": "T2-weighted", "start": 44, "end": 55, "id": 12}, {"text": "sagittal", "start": 56, "end": 64, "id": 13}, {"text": "section", "start": 65, "end": 72, "id": 14}, {"text": "(", "start": 73, "end": 74, "id": 15}, {"text": "B", "start": 74, "end": 75, "id": 16}, {"text": ")", "start": 75, "end": 76, "id": 17}, {"text": "and", "start": 77, "end": 80, "id": 18}, {"text": "T1-weighted", "start": 81, "end": 92, "id": 19}, {"text": "coronal", "start": 93, "end": 100, "id": 20}, {"text": "section", "start": 101, "end": 108, "id": 21}, {"text": "(", "start": 109, "end": 110, "id": 22}, {"text": "C", "start": 110, "end": 111, "id": 23}, {"text": ")", "start": 111, "end": 112, "id": 24}, {"text": "of", "start": 113, "end": 115, "id": 25}, {"text": "cranial", "start": 116, "end": 123, "id": 26}, {"text": "MR", "start": 124, "end": 126, "id": 27}, {"text": "images", "start": 127, "end": 133, "id": 28}, {"text": "show", "start": 134, "end": 138, "id": 29}, {"text": "diffuse", "start": 139, "end": 146, "id": 30}, {"text": "cerebral", "start": 147, "end": 155, "id": 31}, {"text": ",", "start": 155, "end": 156, "id": 32}, {"text": "cerebellar", "start": 157, "end": 167, "id": 33}, {"text": "atrophy", "start": 168, "end": 175, "id": 34}, {"text": "and", "start": 176, "end": 179, "id": 35}, {"text": "ventricular", "start": 180, "end": 191, "id": 36}, {"text": "enlargement", "start": 192, "end": 203, "id": 37}, {"text": "secondary", "start": 204, "end": 213, "id": 38}, {"text": "to", "start": 214, "end": 216, "id": 39}, {"text": "atrophy", "start": 217, "end": 224, "id": 40}, {"text": ".", "start": 224, "end": 225, "id": 41}]}
{"pdf_hash": "4688a9034873154b20cec78d4ea933326ce3b05d", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Forty-four year-old man with a desmoid tumor arising in the left posterior neck region. Evaluation for efficacy of meloxicam according to RECIST criteria was PR. This tumor had T41A mutation. (A) A T2-weighed axial MRI of desmoid (arrows) at the first visit. 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{"pdf_hash": "7ddf338db5b6cef1a53965159e515d82e3045aa2", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 (a) Axial section of CT scan at the level of ethmoid sinuses and orbits showing, left intra-orbital mass with extensive AFS involving bilateral ethmoid sinuses. (b) Axial section of T2-weighted MRI scan showing AFS at the level of ethmoid sinuses and involved left orbit. (c) Axial section of contrast CT scan showing a large left frontal lobe mass, with extensive peri-lesional edema, indicating aspergilloma of left frontal lobe. (d) Axial section of T2 weighted MRI scan, showing massive cerebral edema around left frontal aspergilloma. (e) Coronal section of contrast-enhanced MRI scan showing extension of PNS disease (AFS) into intracranial compartment (InIA). 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{"pdf_hash": "24116e64c1cc44dab8e413e434575af5dc4f93cc", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4. Abdominopelvic CT findings. (A) Typical intussusceptions in the proximal jejunum. (B) Prominent large fungating polyps (white arrows) and intussusceptions (black arrows) in the jejunum. (C) Intussusceptions containing mesenteric vessels and fat. 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{"pdf_hash": "9ff5da14174c1b0abde2eef8d8d096c2c0438e95", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Axial T1-weighted MR image shows an intramedullary bone mass (arrow) with intermediate signal in the greater tuberosity of the proximal right humerus. (B) Axial T2-weighted fat-saturated MR image shows corresponding T2-bright signal in the mass (arrow). (C) Axial unenhanced CT image shows an osteosclerotic intramedullary bone mass (arrow) in the proximal right humerus. (D) 18 F-FDG PET/CT fused image shows increased FDG avidity in the mass with an SUV of 7.4. (E) 18 F-FDG PET image shows a FDG-avid intramedullary bone mass (arrow) in the proximal right humerus before treatment. 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{"pdf_hash": "42527780de2d65a4a4c328745d4d27fbc715cde7", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig. 3. A 78-year-old man with M. kansasii infection. A. Chest radiograph reveals the presence of reticulonodular lesions in both upper lobes, which have decreased in volume. Also note right apical pleural thickening and emphysematous overinflation in remaining lung areas. B. High-resolution (1.0-mm collimation) CT scan obtained at the level of the aortic arch shows consolidation containing the open bronchus sign in the right upper lobe and thin-walled cavity (small arrows), and some areas of consolidation (arrows) in the left upper lobe. 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{"pdf_hash": "6481c282b184fb8423ad629d434b8e4ab7d9fa68", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Figure 5. Inflamed bowel in an 18-year-old male patient with Crohn disease and GI tract bleeding. (a-d) Selected anterior images from 99m Tc-labeled RBC scintigraphy, acquired at 16 seconds (a) and 56 seconds (b) (during flow imaging) and at 10 minutes (c) and 60 minutes (d) (during functional imaging) after injection of the radiotracer, show a region of increased activity in the upper abdomen (arrow), a finding that does not move over time. The persistent radiotracer activity represents increased perfusion and hyperemia in an inflamed small bowel loop. 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{"pdf_hash": "103fb260f74283e6215b84b433637a370bf139a2", "fig_key": "Figure8", "fig_uri": "10-Figure8-1.png", "text": "FIG 8. (a) Guinea pig epidermis, 5 days after the labelling of melanosome complexes. There is no diffuse tracer within the granular cell and even in the str. corneum the tracer forms well defined aggregates some of which still contain identifiable melanosomes (M). K: keratohyalin. X26000. (b) Higher magnification of a melanosome complex within the str. corneum, 4 days after labelling. Partly degraded melanosomes (M) can be recognized which are associated with the tracer. 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{"pdf_hash": "f0597817168826c53933d54b9af8b4526d45884f", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Fig 4. Corneal polarimetric interferometry of type A pattern. Frames of representative raw sequence (A-E) in a case in which the isogyre maintains its corneal cross-shaped pattern with the rotating scan of the LCP. (F) The final summary static image (SUM image) is characterized by a single \"pear shaped\" dark area with the major axis along the horizontal meridians. 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{"pdf_hash": "90ee22d7b5da6c191a72feb2c41ef6c2e123ecc3", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4 a, b.Ganglion cyst in the volar aspect of the wrist in a 55-year-old woman presenting with pain during volar flexion and paresthesia. Axial FS PD-weightedMRI (a) shows a smooth,multiloculated, homogeneously hyperintense lesion located deep and medial to the radial artery (arrow) and lateral to the flexor pollicis longus (dashed arrow) and the flexor carpi radialis (arrowhead) tendons. 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{"pdf_hash": "6e84d4bc77fbc3b642029144ff7c60a6f8b0d669", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Is speckle noise or a feature? (a) Original B-mode image of a breast mass. (b) Speckle reduction applied to the original image. Note that the texture has been removed from the image but major structures remain well-defined. (c) Elastography image of the same mass derived from RF data. Speckle tracking is an implicit or explicit part of elastography. 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{"pdf_hash": "accc16ff8026fcafeb59d5b8c52b8c4a0a20b38e", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1. Locations of the seed regions used for extracting the arcuate fasciculus. (A) The coronal section showing the middle of the internal capsule posterior limb used to identify the core of the arcuate fasciculus (intense triangular shaped area), (B) fiber tracts projecting from A, (C) fiber tracts selected from the level of the anterior commissure in the axial plane that project laterally to the sagittal striatum, and (D) fiber bundles crossing both A and C.", "width": 3158, "height": 1166, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "b": [46, 47, 48, 49, 50, 51, 52, 53], "c": [55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78], "d": [81, 82, 83, 84, 85, 86, 87, 88, 89, 90]}, "subfigures": [{"id": "7ac5c5d8-5434-42e3-9e3c-8d4c555d9705", "label": "a", "points": [[17.7, 94], [17.7, 857.3], [731.1, 857.3], [731.1, 94]], "color": "yellow"}, {"id": "373bf7ae-ef0c-4243-b941-ecbea3a2d2aa", "label": "b", "points": [[771, 99], 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{"pdf_hash": "17ff44a5f38d714fc23ad820df28de26db34efb4", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2: 16-year-old female with an intra-abdominal cystic lymphangioma. T2 weighted single-shot fast spin echo axial (a) and coronal (b) abdominal MRI demonstrates the cystic nature of the 12.8 x 8.9 x 11.3 cm mass with multiple thin septa (solid black arrows) along the lesser curvature of the stomach (broken white arrow). Cyst contents are of uniform hyperintenstity. 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{"pdf_hash": "2a744e76e2fc224b0b2ee00d085b1c02f297a811", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. (A) An example case: a 54-year-old man was diagnosed with advanced hepatocellular carcinoma (HCC) with lung metastasis and treated with metronomic chemotherapy; (a) and (b) are initial abdominal computed tomography scans, which showed a mass in the caudate lobe (a) and multiple hematogenous metastatic nodules in both lungs (b). After three cycles of metronomic chemotherapy, the size of the tumor (c) and pulmonary metastatic lesions (d) had decreased markedly on follow-up computed tomography. (B) Serum vascular endothelial growth factor (VEGF) and alpha-fetoprotein (AFP) levels before and after metronomic chemotherapy in this sample case. 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{"pdf_hash": "2f11fe4ad8567b81a5887cac9f6c8c9e95d3d686", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Contrasted CT scan of the neck; multiple hypoechoic nodules in both lobes of thyroid gland, with the largest nodules containing cystic component at lower pole of the left lobe (red arrow). (B) Multiple enlarged/matted lymph nodes (white arrow) of various sizes occupying along the left cervical level II-V, left supraclavicular region and left-sided superior mediastinum. 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{"pdf_hash": "24b04dc7c71aaae86ad4df2e646e04892ac9aff3", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Examples of piecewise linear fitting. The measured height signal along non-raster scan paths. (a) The recorded height h(t) (top) is split into N segments onto which linear fitting is used to correct the drift component. A corrected height (bottom) results from subtracting the piecewise linear fit from the original data. Because of tilt flattening distorts many of the topographic features. (b) 500 nm diameter Archimedean Spiral showing the grains of evaporated gold where drift data results in rings (raw). Piecewise linear fitting can flatten these artifacts (N \u00bc 300). However, drift related artifacts remain present when too few segments are chosen (N \u00bc 30). 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{"pdf_hash": "f2c9991500eb789422133981c99b40630e8b957d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Chest radiographs. (a) A chest radiograph taken 3 years prior to presentation. (b) A chest radiograph taken on the consultation day. Compared with Panel B, chest radiograph after the completion of treatment with amoxicillin clavulanate (c) shows improvements in infiltrations of the left middle and lower lung fields.", "width": 1322, "height": 502, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "695ac9c5-467e-41a0-be37-45ad8b7be70f", "label": "a", "points": [[18.6, 15], [18.6, 476.6], [455.1, 476.6], [455.1, 15]], "color": "yellow"}, {"id": "8d0744fd-e6b3-40c7-9bba-52b1f10751c0", "label": "b", "points": [[467.6, 474.5], [467.6, 2.5], [883.2, 2.5], [883.2, 474.5]], "color": "cyan"}, {"id": "8544d3d3-d651-413b-9f3c-f884dfd4d3de", "label": "c", "points": [[891.6, 0.4], [891.6, 470.3], [1280, 470.3], [1280, 0.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Chest", "start": 8, "end": 13, "id": 4}, {"text": "radiographs", "start": 14, "end": 25, "id": 5}, {"text": ".", "start": 25, "end": 26, "id": 6}, {"text": "(", "start": 27, "end": 28, "id": 7}, {"text": "a", "start": 28, "end": 29, "id": 8}, {"text": ")", "start": 29, "end": 30, "id": 9}, {"text": "A", "start": 31, "end": 32, "id": 10}, {"text": "chest", "start": 33, "end": 38, "id": 11}, {"text": "radiograph", "start": 39, "end": 49, "id": 12}, {"text": "taken", "start": 50, "end": 55, "id": 13}, {"text": "3", "start": 56, "end": 57, "id": 14}, {"text": "years", "start": 58, "end": 63, "id": 15}, {"text": "prior", "start": 64, "end": 69, "id": 16}, {"text": "to", "start": 70, "end": 72, "id": 17}, {"text": "presentation", "start": 73, "end": 85, "id": 18}, {"text": ".", "start": 85, "end": 86, "id": 19}, {"text": "(", "start": 87, "end": 88, "id": 20}, {"text": "b", "start": 88, "end": 89, "id": 21}, {"text": ")", "start": 89, "end": 90, "id": 22}, {"text": "A", "start": 91, "end": 92, "id": 23}, {"text": "chest", "start": 93, "end": 98, "id": 24}, {"text": "radiograph", "start": 99, "end": 109, "id": 25}, {"text": "taken", "start": 110, "end": 115, "id": 26}, {"text": "on", "start": 116, "end": 118, "id": 27}, {"text": "the", "start": 119, "end": 122, "id": 28}, {"text": "consultation", "start": 123, "end": 135, "id": 29}, {"text": "day", "start": 136, "end": 139, "id": 30}, {"text": ".", "start": 139, "end": 140, "id": 31}, {"text": "Compared", "start": 141, "end": 149, "id": 32}, {"text": "with", "start": 150, "end": 154, "id": 33}, {"text": "Panel", "start": 155, "end": 160, "id": 34}, {"text": "B", "start": 161, "end": 162, "id": 35}, {"text": ",", "start": 162, "end": 163, "id": 36}, {"text": "chest", "start": 164, "end": 169, "id": 37}, {"text": "radiograph", "start": 170, "end": 180, "id": 38}, {"text": "after", "start": 181, "end": 186, "id": 39}, {"text": "the", "start": 187, "end": 190, "id": 40}, {"text": "completion", "start": 191, "end": 201, "id": 41}, {"text": "of", "start": 202, "end": 204, "id": 42}, {"text": "treatment", "start": 205, "end": 214, "id": 43}, {"text": "with", "start": 215, "end": 219, "id": 44}, {"text": "amoxicillin", "start": 220, "end": 231, "id": 45}, {"text": "clavulanate", "start": 232, "end": 243, "id": 46}, {"text": "(", "start": 244, "end": 245, "id": 47}, {"text": "c", "start": 245, "end": 246, "id": 48}, {"text": ")", "start": 246, "end": 247, "id": 49}, {"text": "shows", "start": 248, "end": 253, "id": 50}, {"text": "improvements", "start": 254, "end": 266, "id": 51}, {"text": "in", "start": 267, "end": 269, "id": 52}, {"text": "infiltrations", "start": 270, "end": 283, "id": 53}, {"text": "of", "start": 284, "end": 286, "id": 54}, {"text": "the", "start": 287, "end": 290, "id": 55}, {"text": "left", "start": 291, "end": 295, "id": 56}, {"text": "middle", "start": 296, "end": 302, "id": 57}, {"text": "and", "start": 303, "end": 306, "id": 58}, {"text": "lower", "start": 307, "end": 312, "id": 59}, {"text": "lung", "start": 313, "end": 317, "id": 60}, {"text": "fields", "start": 318, "end": 324, "id": 61}, {"text": ".", "start": 324, "end": 325, "id": 62}]}
{"pdf_hash": "718fc3e1d810114984dc22d924566e6f359e2b2a", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Fig 2. Autoradiographs from the same sample of rat lung macrophages after inhalation of PuO 2 . Nuclear track emulsion (a), plastic detector TASTRAK\u2122 (b) and iQID autoradiographs (c). Exposure time is displayed on the lower left corner of each image. w: week; h: hours. Nuclear track emulsion technique was done last as it is a destructive endpoint. Three points of origin for appreciation of the spatial relationships and resolution of the tracks via each system are circled together in each frame. Emulsion-and plastic-based autoradiographs were observed with objective 2. 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{"pdf_hash": "58e081c223a695207a92390dadbb68885dee7b90", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3 CT images of response to first-line palliative chemotherapy for inoperable and metastatic pulmonary artery sarcoma. (a) A 57-yearold woman with intimal sarcoma after three cycles of pegylated liposomal doxorubicin hydrochloride. (b) A 64-year-old man with intimal sarcoma with rhabdomyosarcomatous differentiation after six cycles of vincristine, ifosfamide and doxorubicin chemotherapy.", "width": 850, "height": 666, "subcaptions": {"a": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "5232433a-3c5f-440e-8e68-db532698a82a", "label": "a", "points": [[34.3, 52.1], [34.3, 324.7], [411.6, 324.7], [411.6, 52.1]], "color": "yellow"}, {"id": "cbd9f36a-45ff-44bb-8656-c679f497c440", "label": "a", "points": [[426.4, 53.5], [426.4, 326.1], [814.4, 326.1], [814.4, 53.5]], "color": "cyan"}, {"id": "5deb3f99-4c21-45af-9d46-56a0c76d98b5", "label": "b", "points": [[28.9, 361], [28.9, 636.2], [407.6, 636.2], [407.6, 361]], "color": "magenta"}, {"id": "bfadefed-236f-48fb-9e3f-da75283bb54d", "label": "b", "points": [[427.7, 365], [427.7, 637.6], [815.8, 637.6], [815.8, 365]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "CT", "start": 9, "end": 11, "id": 2}, {"text": "images", "start": 12, "end": 18, "id": 3}, {"text": "of", "start": 19, "end": 21, "id": 4}, {"text": "response", "start": 22, "end": 30, "id": 5}, {"text": "to", "start": 31, "end": 33, "id": 6}, {"text": "first", "start": 34, "end": 39, "id": 7}, {"text": "-", "start": 39, "end": 40, "id": 8}, {"text": "line", "start": 40, "end": 44, "id": 9}, {"text": "palliative", "start": 45, "end": 55, "id": 10}, {"text": "chemotherapy", "start": 56, "end": 68, "id": 11}, {"text": "for", "start": 69, "end": 72, "id": 12}, {"text": "inoperable", "start": 73, "end": 83, "id": 13}, {"text": "and", "start": 84, "end": 87, "id": 14}, {"text": "metastatic", "start": 88, "end": 98, "id": 15}, {"text": "pulmonary", "start": 99, "end": 108, "id": 16}, {"text": "artery", "start": 109, "end": 115, "id": 17}, {"text": "sarcoma", "start": 116, "end": 123, "id": 18}, {"text": ".", "start": 123, "end": 124, "id": 19}, {"text": "(", "start": 125, "end": 126, "id": 20}, {"text": "a", "start": 126, "end": 127, "id": 21}, {"text": ")", "start": 127, "end": 128, "id": 22}, {"text": "A", "start": 129, "end": 130, "id": 23}, {"text": "57-yearold", "start": 131, "end": 141, "id": 24}, {"text": "woman", "start": 142, "end": 147, "id": 25}, {"text": "with", "start": 148, "end": 152, "id": 26}, {"text": "intimal", "start": 153, "end": 160, "id": 27}, {"text": "sarcoma", "start": 161, "end": 168, "id": 28}, {"text": "after", "start": 169, "end": 174, "id": 29}, {"text": "three", "start": 175, "end": 180, "id": 30}, {"text": "cycles", "start": 181, "end": 187, "id": 31}, {"text": "of", "start": 188, "end": 190, "id": 32}, {"text": "pegylated", "start": 191, "end": 200, "id": 33}, {"text": "liposomal", "start": 201, "end": 210, "id": 34}, {"text": "doxorubicin", "start": 211, "end": 222, "id": 35}, {"text": "hydrochloride", "start": 223, "end": 236, "id": 36}, {"text": ".", "start": 236, "end": 237, "id": 37}, {"text": "(", "start": 238, "end": 239, "id": 38}, {"text": "b", "start": 239, "end": 240, "id": 39}, {"text": ")", "start": 240, "end": 241, "id": 40}, {"text": "A", "start": 242, "end": 243, "id": 41}, {"text": "64-year", "start": 244, "end": 251, "id": 42}, {"text": "-", "start": 251, "end": 252, "id": 43}, {"text": "old", "start": 252, "end": 255, "id": 44}, {"text": "man", "start": 256, "end": 259, "id": 45}, {"text": "with", "start": 260, "end": 264, "id": 46}, {"text": "intimal", "start": 265, "end": 272, "id": 47}, {"text": "sarcoma", "start": 273, "end": 280, "id": 48}, {"text": "with", "start": 281, "end": 285, "id": 49}, {"text": "rhabdomyosarcomatous", "start": 286, "end": 306, "id": 50}, {"text": "differentiation", "start": 307, "end": 322, "id": 51}, {"text": "after", "start": 323, "end": 328, "id": 52}, {"text": "six", "start": 329, "end": 332, "id": 53}, {"text": "cycles", "start": 333, "end": 339, "id": 54}, {"text": "of", "start": 340, "end": 342, "id": 55}, {"text": "vincristine", "start": 343, "end": 354, "id": 56}, {"text": ",", "start": 354, "end": 355, "id": 57}, {"text": "ifosfamide", "start": 356, "end": 366, "id": 58}, {"text": "and", "start": 367, "end": 370, "id": 59}, {"text": "doxorubicin", "start": 371, "end": 382, "id": 60}, {"text": "chemotherapy", "start": 383, "end": 395, "id": 61}, {"text": ".", "start": 395, "end": 396, "id": 62}]}
{"pdf_hash": "6f1d3c5881626b171863340022f00fd368eb07c2", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 13-year-old boy with corrected TGA and EF 40 %. MRI (bSSFP sequences) in a coronal oblique projection (a) shows a finger-like projection of the IVMS (arrows) into the RVOT; in the sagittal oblique projection (b) through the RV shows the round tip of the IVMS aneurysm in the RV cavity", "width": 1044, "height": 474, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "59dcbbaa-0fd5-4c01-b680-8a6e7135db42", "label": "b", "points": [[551.3, 31.1], [551.3, 471.4], [1037.8, 471.4], [1037.8, 31.1]], "color": "cyan"}, {"id": "d049aea1-165e-45a3-8546-32c4983b1af6", "label": "a", "points": [[26.9, 32.8], [26.9, 471.4], [523.3, 471.4], [523.3, 32.8]], "color": "yellow"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "13-year", "start": 7, "end": 14, "id": 3}, {"text": "-", "start": 14, "end": 15, "id": 4}, {"text": "old", "start": 15, "end": 18, "id": 5}, {"text": "boy", "start": 19, "end": 22, "id": 6}, {"text": "with", "start": 23, "end": 27, "id": 7}, {"text": "corrected", "start": 28, "end": 37, "id": 8}, {"text": "TGA", "start": 38, "end": 41, "id": 9}, {"text": "and", "start": 42, "end": 45, "id": 10}, {"text": "EF", "start": 46, "end": 48, "id": 11}, {"text": "40", "start": 49, "end": 51, "id": 12}, {"text": "%", "start": 52, "end": 53, "id": 13}, {"text": ".", "start": 53, "end": 54, "id": 14}, {"text": "MRI", "start": 55, "end": 58, "id": 15}, {"text": "(", "start": 59, "end": 60, "id": 16}, {"text": "bSSFP", "start": 60, "end": 65, "id": 17}, {"text": "sequences", "start": 66, "end": 75, "id": 18}, {"text": ")", "start": 75, "end": 76, "id": 19}, {"text": "in", "start": 77, "end": 79, "id": 20}, {"text": "a", "start": 80, "end": 81, "id": 21}, {"text": "coronal", "start": 82, "end": 89, "id": 22}, {"text": "oblique", "start": 90, "end": 97, "id": 23}, {"text": "projection", "start": 98, "end": 108, "id": 24}, {"text": "(", "start": 109, "end": 110, "id": 25}, {"text": "a", "start": 110, "end": 111, "id": 26}, {"text": ")", "start": 111, "end": 112, "id": 27}, {"text": "shows", "start": 113, "end": 118, "id": 28}, {"text": "a", "start": 119, "end": 120, "id": 29}, {"text": "finger", "start": 121, "end": 127, "id": 30}, {"text": "-", "start": 127, "end": 128, "id": 31}, {"text": "like", "start": 128, "end": 132, "id": 32}, {"text": "projection", "start": 133, "end": 143, "id": 33}, {"text": "of", "start": 144, "end": 146, "id": 34}, {"text": "the", "start": 147, "end": 150, "id": 35}, {"text": "IVMS", "start": 151, "end": 155, "id": 36}, {"text": "(", "start": 156, "end": 157, "id": 37}, {"text": "arrows", "start": 157, "end": 163, "id": 38}, {"text": ")", "start": 163, "end": 164, "id": 39}, {"text": "into", "start": 165, "end": 169, "id": 40}, {"text": "the", "start": 170, "end": 173, "id": 41}, {"text": "RVOT", "start": 174, "end": 178, "id": 42}, {"text": ";", "start": 178, "end": 179, "id": 43}, {"text": "in", "start": 180, "end": 182, "id": 44}, {"text": "the", "start": 183, "end": 186, "id": 45}, {"text": "sagittal", "start": 187, "end": 195, "id": 46}, {"text": "oblique", "start": 196, "end": 203, "id": 47}, {"text": "projection", "start": 204, "end": 214, "id": 48}, {"text": "(", "start": 215, "end": 216, "id": 49}, {"text": "b", "start": 216, "end": 217, "id": 50}, {"text": ")", "start": 217, "end": 218, "id": 51}, {"text": "through", "start": 219, "end": 226, "id": 52}, {"text": "the", "start": 227, "end": 230, "id": 53}, {"text": "RV", "start": 231, "end": 233, "id": 54}, {"text": "shows", "start": 234, "end": 239, "id": 55}, {"text": "the", "start": 240, "end": 243, "id": 56}, {"text": "round", "start": 244, "end": 249, "id": 57}, {"text": "tip", "start": 250, "end": 253, "id": 58}, {"text": "of", "start": 254, "end": 256, "id": 59}, {"text": "the", "start": 257, "end": 260, "id": 60}, {"text": "IVMS", "start": 261, "end": 265, "id": 61}, {"text": "aneurysm", "start": 266, "end": 274, "id": 62}, {"text": "in", "start": 275, "end": 277, "id": 63}, {"text": "the", "start": 278, "end": 281, "id": 64}, {"text": "RV", "start": 282, "end": 284, "id": 65}, {"text": "cavity", "start": 285, "end": 291, "id": 66}]}
{"pdf_hash": "08c3701de96c47e047702805dcae5b32b2eaebb4", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Case 1, 47-year-old woman with wandering spleen. (A-C) Coronal CT and (D-F) coronal fused PET/CT images. The normal splenic bed in the left upper quadrant is empty. There is a large soft tissue mass in the left lower abdomen representing an ectopic spleen. 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{"pdf_hash": "c35df1bf71e138770aac08140713644e2e5a529f", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Initial ankle X-rays Figure 2: Initial computed tomography scan (coronal and axial views)", "width": 740, "height": 310, "subcaptions": {"a": [0, 1, 2, 3, 4, 5, 6, 7], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20]}, "subfigures": [{"id": "dd577c11-c654-4d28-b03e-618c7f1c7f22", "label": "a", "points": [[2.7, 30.2], [2.7, 302.6], [360.4, 302.6], [360.4, 30.2]], "color": "yellow"}, {"id": "b97c02db-077c-4ae0-b80b-daa4463e10de", "label": "b", "points": [[363.9, 22.1], [363.9, 309.6], [704, 309.6], [704, 22.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Initial", "start": 10, "end": 17, "id": 3}, {"text": "ankle", "start": 18, "end": 23, "id": 4}, {"text": "X", "start": 24, "end": 25, "id": 5}, {"text": "-", "start": 25, "end": 26, "id": 6}, {"text": "rays", "start": 26, "end": 30, "id": 7}, {"text": "Figure", "start": 31, "end": 37, "id": 8}, {"text": "2", "start": 38, "end": 39, "id": 9}, {"text": ":", "start": 39, "end": 40, "id": 10}, {"text": "Initial", "start": 41, "end": 48, "id": 11}, {"text": "computed", "start": 49, "end": 57, "id": 12}, {"text": "tomography", "start": 58, "end": 68, "id": 13}, {"text": "scan", "start": 69, "end": 73, "id": 14}, {"text": "(", "start": 74, "end": 75, "id": 15}, {"text": "coronal", "start": 75, "end": 82, "id": 16}, {"text": "and", "start": 83, "end": 86, "id": 17}, {"text": "axial", "start": 87, "end": 92, "id": 18}, {"text": "views", "start": 93, "end": 98, "id": 19}, {"text": ")", "start": 98, "end": 99, "id": 20}]}
{"pdf_hash": "df7adaabffa4eff128572302e0444adf6d4465b6", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Figure 4. Antitumor effects and distribution kinetics of infused cells. (A) Serial CT scans of gallium avid tumor in a patient with diffuse large B cell lymphoma who remained in complete remission 60 months after haploidentical immunotherapy in the absence of any additional therapy. Note the slow tumor regression over time. The most recent restaging with PET/CT scan performed in May 2007 was negative for recurrent disease (data not shown). (B) Transient response to haplo immunotherapy as demonstrated by representative serial bone marrow results in a patient with AML. At 3 days after cell infusion, a marked response to therapy is evident, with loss of myeloblasts and some edema. 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{"pdf_hash": "bcbfaa39ed30d402991649d2ab10d4bc54ef7b63", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Two-dimensional echocardiography of the proband. (a) The left ventricular chamber size of the proband is normal, but the left ventricular wall is thickened, measuring between 13 and 18 mm (arrow). (b) There is no abnormality of the left ventricular systolic activity. The left ventricular ejection fraction is 57%. The right ventricular free wall has a thickness of 7 mm (arrow). (c, d) The right ventricular chamber size is normal. Doppler echocardiography shows an impaired left ventricular diastolic function. 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{"pdf_hash": "44ad5bd0443935b6b282dce9b711b7d7733d0802", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5 CT and bronchoscopic findings seen before procedural enhancements: (A and B) A 4 mm granuloma indicated by white arrows on both transverse CT and bronchoscopic images. (C and D) Superficial airway effect indicated by white arrow on the bronchoscopic image with normal transverse CT image. (E and F) A 1.5 mm perforation through carina indicated by white arrows on both coronal CT and bronchoscopic images.", "width": 1050, "height": 1150, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "b": [54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76]}, "subfigures": [{"id": "6ccd190e-ea0d-4cd2-80e0-9ee0f5fcc0ee", "label": "a", "points": [[26.5, 0], [26.5, 368.2], [693.4, 368.2], [693.4, 0]], "color": "yellow"}, {"id": "c4081a08-39a4-4d48-ad86-07b54ebee7b0", "label": "a", "points": [[698.3, 369.9], [698.3, 5], [1028.4, 5], [1028.4, 369.9]], "color": "cyan"}, {"id": "0f967186-a13a-44a3-924b-9bd6ae6f77e4", "label": "b", "points": [[358.3, 741.5], [358.3, 371.6], [29.9, 371.6], [29.9, 741.5]], "color": "magenta"}, {"id": "9ae7d866-f08f-4117-9f46-0ed1cc16dc66", "label": "b", "points": [[364.9, 746.5], [364.9, 376.5], [1026.8, 376.5], [1026.8, 746.5]], "color": "springgreen"}, {"id": 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{"pdf_hash": "9750b2e59d441c7abb104341f55f6c501abe544b", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Computed tomography (CT) scans of subdural hematoma in the present case at presentation (a), on the day after the first operation (b), on the 6th day immediately before the second operation (c), and on the 24th day (d).", "width": 920, "height": 988, "subcaptions": {"a": [16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "d": [47, 48, 49, 50, 51, 52, 53]}, "subfigures": [{"id": "a4bc181b-87be-4d85-91ec-0afd9fb4ce25", "label": "a", "points": [[34.2, 4.1], [34.2, 470.6], [449.9, 470.6], [449.9, 4.1]], "color": "yellow"}, {"id": "fc5c90d2-b9e1-4194-b000-8ed2fd558e93", "label": "b", "points": [[468.7, 4.1], [468.7, 472.1], [891.7, 472.1], [891.7, 4.1]], "color": "cyan"}, {"id": "1dda5a01-9625-4482-937e-0332db2b6edd", "label": "c", "points": [[31.3, 489.5], [31.3, 948.8], [458.6, 948.8], [458.6, 489.5]], "color": "magenta"}, {"id": "d235f7fe-cf4c-44d7-8fe0-52c9b10a95d5", "label": "d", "points": [[470.2, 486.6], [470.2, 950.2], [887.3, 950.2], [887.3, 486.6]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomography", "start": 19, "end": 29, "id": 4}, {"text": "(", "start": 30, "end": 31, "id": 5}, {"text": "CT", "start": 31, "end": 33, "id": 6}, {"text": ")", "start": 33, "end": 34, "id": 7}, {"text": "scans", "start": 35, "end": 40, "id": 8}, {"text": "of", "start": 41, "end": 43, "id": 9}, {"text": "subdural", "start": 44, "end": 52, "id": 10}, {"text": "hematoma", "start": 53, "end": 61, "id": 11}, {"text": "in", "start": 62, "end": 64, "id": 12}, {"text": "the", "start": 65, "end": 68, "id": 13}, {"text": "present", "start": 69, "end": 76, "id": 14}, {"text": "case", "start": 77, "end": 81, "id": 15}, {"text": "at", "start": 82, "end": 84, "id": 16}, {"text": "presentation", "start": 85, "end": 97, "id": 17}, {"text": "(", "start": 98, "end": 99, "id": 18}, {"text": "a", "start": 99, "end": 100, "id": 19}, {"text": ")", "start": 100, "end": 101, "id": 20}, {"text": ",", "start": 101, "end": 102, "id": 21}, {"text": "on", "start": 103, "end": 105, "id": 22}, {"text": "the", "start": 106, "end": 109, "id": 23}, {"text": "day", "start": 110, "end": 113, "id": 24}, {"text": "after", "start": 114, "end": 119, "id": 25}, {"text": "the", "start": 120, "end": 123, "id": 26}, {"text": "first", "start": 124, "end": 129, "id": 27}, {"text": "operation", "start": 130, "end": 139, "id": 28}, {"text": "(", "start": 140, "end": 141, "id": 29}, {"text": "b", "start": 141, "end": 142, "id": 30}, {"text": ")", "start": 142, "end": 143, "id": 31}, {"text": ",", "start": 143, "end": 144, "id": 32}, {"text": "on", "start": 145, "end": 147, "id": 33}, {"text": "the", "start": 148, "end": 151, "id": 34}, {"text": "6th", "start": 152, "end": 155, "id": 35}, {"text": "day", "start": 156, "end": 159, "id": 36}, {"text": "immediately", "start": 160, "end": 171, "id": 37}, {"text": "before", "start": 172, "end": 178, "id": 38}, {"text": "the", "start": 179, "end": 182, "id": 39}, {"text": "second", "start": 183, "end": 189, "id": 40}, {"text": "operation", "start": 190, "end": 199, "id": 41}, {"text": "(", "start": 200, "end": 201, "id": 42}, {"text": "c", "start": 201, "end": 202, "id": 43}, {"text": ")", "start": 202, "end": 203, "id": 44}, {"text": ",", "start": 203, "end": 204, "id": 45}, {"text": "and", "start": 205, "end": 208, "id": 46}, {"text": "on", "start": 209, "end": 211, "id": 47}, {"text": "the", "start": 212, "end": 215, "id": 48}, {"text": "24th", "start": 216, "end": 220, "id": 49}, {"text": "day", "start": 221, "end": 224, "id": 50}, {"text": "(", "start": 225, "end": 226, "id": 51}, {"text": "d", "start": 226, "end": 227, "id": 52}, {"text": ")", "start": 227, "end": 228, "id": 53}, {"text": ".", "start": 228, "end": 229, "id": 54}]}
{"pdf_hash": "469ed6c62222840b3cd356c032d3f975f4b98404", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "FIG. 1. A 55-year-old male patient who received OLT due to HCV cirrhosis. Pre- and post-LT CT show increasing size and number of PCLs. (A) Pre-LT, venous phase axial CT image shows a small pancreatic cyst at the head of the pancreas (arrow). (B) PreLT, venous phase axial CT image shows absence of additional cysts in the rest of the pancreas. (C) At 4 years after LT, venous phase axial CT image shows interval increase in size of the cyst in the pancreatic head from 0.5 to 1.2 cm (arrow). 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{"pdf_hash": "771a7a85ef5c5abf8d4bc9f62a815d49a7f09753", "fig_key": "Figure8", "fig_uri": "11-Figure8-1.png", "text": "Figure 8. Superior colliculi and tracer dynamics of Patient A. (A) Non-motion corrected image. (B) MAF corrected, (C) LORMC corrected PET images of Patient A, and (D) the corresponding MP-RAGE slice. The red arrows mark the superior colliculi. Uptake is visible only in the motion corrected PET images. (E) Dynamic study of the uptake in the basal ganglia. Error bars show the standard deviation of uptake values in the region of interest. 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{"pdf_hash": "c5fca8ebeca8091dc2288485f952625e0e812ce4", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4 A digital atlas: high-resolution display and orthogonal sections. A high-resolution view of the image data, an MRM volume and a Nissl-stained volume from a d100 mouse (shown overlaid), is presented the user, much like a traditional atlas. Small, low-resolution thumbnails are for navigation; b, sagittal, c, transverse (coronal), and d, horizontal sections through two volumes.", "width": 634, "height": 650, "subcaptions": {"a": [0], "b": [64, 65, 66, 67], "c": [68, 69, 70, 71, 72, 73], "d": [76, 77, 78]}, "subfigures": [{"id": "2dd9bb16-a1eb-48c0-94cc-41d1c30e77e3", "label": "a", "points": [[3, 4], [3, 431.7], [630, 431.7], [630, 4]], "color": "yellow"}, {"id": "ff37c634-3034-498d-a505-56ced1291e12", "label": "b", "points": [[1, 644], [1, 440.7], [205.3, 440.7], [205.3, 644]], "color": "cyan"}, {"id": "113f3a88-12f0-4a24-805a-47f6a2ae61ce", "label": "c", "points": [[215.3, 440.7], [215.3, 647], [419.7, 647], [419.7, 440.7]], "color": "magenta"}, {"id": "e4d404b1-61a0-436a-b717-8b426ab37792", "label": "d", "points": [[423.7, 646], [423.7, 439.7], [630, 439.7], [630, 646]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", 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{"pdf_hash": "607342b05342248f964acbab77673b47b31146ce", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Response to chemotherapy with CBDCA with nab-PAC. (A) Fluorodeoxyglucose positron emission CT images showing liver invasion during conventional chemotherapy with CBDCA plus solvent-based paclitaxel. (B) Plain CT images prior to chemotherapy with CBDCA plus nab-PAC (left); following three cycles of chemotherapy (right), the reduction in the tumor size is shown. White dotted lines show the margins of the tumor. 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{"pdf_hash": "a0ad71f552b7fe4e19766ef6004f108246478d2a", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 A: Computed tomography (CT) scan on admission revealing subarachnoid hemorrhage in the basal cisterns and bilateral sylvian fissures. Subarachnoid hemorrhage is clearly apparent on the right side. B: Three-dimensional CT angiogram showing an extrorse saccular aneurysm (thick arrow) of the right internal carotid artery. 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{"pdf_hash": "3a7ab1bf44a472b6e3ef5c5c2e1433c67b0702a7", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIGURE 2. A 52-year-old woman eventually requiring removal of the bone flap caused by recurrent epidural fluid collection (EFC). A: Computed tomography (CT) scan 5 days post-cranioplasty; EFC is seen in the epidural space. Midline shift is evident, as is the presence of air bubbles. B: Evacuation of fluid through a 5 L catheter. The mass effect with midline shift is resolved. C: Four days after removal of the catheter, a CT image shows recurrent EFC with significant midline shift. D: The collected fluid was removed again with a 5 L catheter. E: Three days after the second trephination procedure, EFC was observed at the same lesion site; significant midline shift and a large number of air bubbles are evident in the CT image.", "width": 1262, "height": 948, "subcaptions": {"a": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59], "b": [60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79], "c": [80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100], "d": [101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114], "e": [115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150]}, "subfigures": [{"id": "5a9f1b82-9354-4049-81f2-2747dad3cd54", "label": "a", "points": [[2, 0], [2, 460.5], [422.7, 460.5], [422.7, 0]], "color": "yellow"}, {"id": 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{"pdf_hash": "d6edbfafc58a72844a6a2b92b1b96e66a492428b", "fig_key": "Figure13", "fig_uri": "9-Figure13-1.png", "text": "Fig. 13 Ablation planning: MW virtual probe with predicted ablation area (manufacturer specific) overlaying to segmented lesion with 5 mm safe margins covered in axial (13a) and progression view visualization (13b). Fig. 14 Intra-procedural CBCT: wrong MW probe placement (14a, b) with upper zone of lesion uncovered by the predictable ablation area (14b); and subsequent repositioning with all lesion with 5 mm safe margins covered by the predictable ablation area. 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{"pdf_hash": "7ec769b52958f638555a1127ab0b93035de87d9d", "fig_key": "Figure8", "fig_uri": "6-Figure8-1.png", "text": "Figure 8 Dynamic ultrasound of the ankle: a: fibular tendons in place; b: during inversion: the tendons are dislocated.", "width": 1292, "height": 504, "subcaptions": {"a": [8, 9, 10, 11, 12, 13], "b": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24]}, "subfigures": [{"id": "c44175f0-517a-49ca-9765-782f7be31bd6", "label": "a", "points": [[33.8, 30.3], [33.8, 465], [658.3, 465], [658.3, 30.3]], "color": "yellow"}, {"id": "a618d5d9-1d07-4739-bb29-19b35bbdd712", "label": "b", "points": [[680.8, 32.3], [680.8, 473.2], [1256.3, 473.2], [1256.3, 32.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "8", "start": 7, "end": 8, "id": 1}, {"text": "Dynamic", "start": 9, "end": 16, "id": 2}, {"text": "ultrasound", "start": 17, "end": 27, "id": 3}, {"text": "of", "start": 28, "end": 30, "id": 4}, {"text": "the", "start": 31, "end": 34, "id": 5}, {"text": "ankle", "start": 35, "end": 40, "id": 6}, {"text": ":", "start": 40, "end": 41, "id": 7}, {"text": "a", "start": 42, "end": 43, "id": 8}, {"text": ":", "start": 43, "end": 44, "id": 9}, {"text": "fibular", "start": 45, "end": 52, "id": 10}, {"text": "tendons", "start": 53, "end": 60, "id": 11}, {"text": "in", "start": 61, "end": 63, "id": 12}, {"text": "place", "start": 64, "end": 69, "id": 13}, {"text": ";", "start": 69, "end": 70, "id": 14}, {"text": "b", "start": 71, "end": 72, "id": 15}, {"text": ":", "start": 72, "end": 73, "id": 16}, {"text": "during", "start": 74, "end": 80, "id": 17}, {"text": "inversion", "start": 81, "end": 90, "id": 18}, {"text": ":", "start": 90, "end": 91, "id": 19}, {"text": "the", "start": 92, "end": 95, "id": 20}, {"text": "tendons", "start": 96, "end": 103, "id": 21}, {"text": "are", "start": 104, "end": 107, "id": 22}, {"text": "dislocated", "start": 108, "end": 118, "id": 23}, {"text": ".", "start": 118, "end": 119, "id": 24}]}
{"pdf_hash": "4ea37d5a67a893fd2b95e01ffe4d638be0679c31", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Figure 5. Case 2 A and B. Figure; CT of Liver metastasis pancreatic cancer; (A) Before treatment; Thick poorly defined liver-tumor interface with heterogeneous attenuation (arrow), morphology group 3. (B) After treatment; thin partially defined liver-tumor interface with homogenous low attenuation and some peripheral enhancement (arrow), morphology group 2 (Incomplete morphological response).", "width": 630, "height": 316, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74]}, "subfigures": [{"id": "8223aeeb-0033-4d2a-bd2d-fd0809cc5290", "label": "a", "points": [[2.8, 0.9], [2.8, 286.9], [306.8, 286.9], [306.8, 0.9]], "color": "yellow"}, {"id": "84ac14ae-0f8f-42c7-9078-f6a4201da059", "label": "b", "points": [[324.8, 0.9], [324.8, 297.9], [630.8, 297.9], [630.8, 0.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Case", "start": 10, "end": 14, "id": 3}, {"text": "2", "start": 15, "end": 16, "id": 4}, {"text": "A", "start": 17, "end": 18, "id": 5}, {"text": "and", "start": 19, "end": 22, "id": 6}, {"text": "B.", "start": 23, "end": 25, "id": 7}, {"text": "Figure", "start": 26, "end": 32, "id": 8}, {"text": ";", "start": 32, "end": 33, "id": 9}, {"text": "CT", "start": 34, "end": 36, "id": 10}, {"text": "of", "start": 37, "end": 39, "id": 11}, {"text": "Liver", "start": 40, "end": 45, "id": 12}, {"text": "metastasis", "start": 46, "end": 56, "id": 13}, {"text": "pancreatic", "start": 57, "end": 67, "id": 14}, {"text": "cancer", "start": 68, "end": 74, "id": 15}, {"text": ";", "start": 74, "end": 75, "id": 16}, {"text": "(", "start": 76, "end": 77, "id": 17}, {"text": "A", "start": 77, "end": 78, "id": 18}, {"text": ")", "start": 78, "end": 79, "id": 19}, {"text": "Before", "start": 80, "end": 86, "id": 20}, {"text": "treatment", "start": 87, "end": 96, "id": 21}, {"text": ";", "start": 96, "end": 97, "id": 22}, {"text": "Thick", "start": 98, "end": 103, "id": 23}, {"text": "poorly", "start": 104, "end": 110, "id": 24}, {"text": "defined", "start": 111, "end": 118, "id": 25}, {"text": "liver", "start": 119, "end": 124, "id": 26}, {"text": "-", "start": 124, "end": 125, "id": 27}, {"text": "tumor", "start": 125, "end": 130, "id": 28}, {"text": "interface", "start": 131, "end": 140, "id": 29}, {"text": "with", "start": 141, "end": 145, "id": 30}, {"text": "heterogeneous", "start": 146, "end": 159, "id": 31}, {"text": "attenuation", "start": 160, "end": 171, "id": 32}, {"text": "(", "start": 172, "end": 173, "id": 33}, {"text": "arrow", "start": 173, "end": 178, "id": 34}, {"text": ")", "start": 178, "end": 179, "id": 35}, {"text": ",", "start": 179, "end": 180, "id": 36}, {"text": "morphology", "start": 181, "end": 191, "id": 37}, {"text": "group", "start": 192, "end": 197, "id": 38}, {"text": "3", "start": 198, "end": 199, "id": 39}, {"text": ".", "start": 199, "end": 200, "id": 40}, {"text": "(", "start": 201, "end": 202, "id": 41}, {"text": "B", "start": 202, "end": 203, "id": 42}, {"text": ")", "start": 203, "end": 204, "id": 43}, {"text": "After", "start": 205, "end": 210, "id": 44}, {"text": "treatment", "start": 211, "end": 220, "id": 45}, {"text": ";", "start": 220, "end": 221, "id": 46}, {"text": "thin", "start": 222, "end": 226, "id": 47}, {"text": "partially", "start": 227, "end": 236, "id": 48}, {"text": "defined", "start": 237, "end": 244, "id": 49}, {"text": "liver", "start": 245, "end": 250, "id": 50}, {"text": "-", "start": 250, "end": 251, "id": 51}, {"text": "tumor", "start": 251, "end": 256, "id": 52}, {"text": "interface", "start": 257, "end": 266, "id": 53}, {"text": "with", "start": 267, "end": 271, "id": 54}, {"text": "homogenous", "start": 272, "end": 282, "id": 55}, {"text": "low", "start": 283, "end": 286, "id": 56}, {"text": "attenuation", "start": 287, "end": 298, "id": 57}, {"text": "and", "start": 299, "end": 302, "id": 58}, {"text": "some", "start": 303, "end": 307, "id": 59}, {"text": "peripheral", "start": 308, "end": 318, "id": 60}, {"text": "enhancement", "start": 319, "end": 330, "id": 61}, {"text": "(", "start": 331, "end": 332, "id": 62}, {"text": "arrow", "start": 332, "end": 337, "id": 63}, {"text": ")", "start": 337, "end": 338, "id": 64}, {"text": ",", "start": 338, "end": 339, "id": 65}, {"text": "morphology", "start": 340, "end": 350, "id": 66}, {"text": "group", "start": 351, "end": 356, "id": 67}, {"text": "2", "start": 357, "end": 358, "id": 68}, {"text": "(", "start": 359, "end": 360, "id": 69}, {"text": "Incomplete", "start": 360, "end": 370, "id": 70}, {"text": "morphological", "start": 371, "end": 384, "id": 71}, {"text": "response", "start": 385, "end": 393, "id": 72}, {"text": ")", "start": 393, "end": 394, "id": 73}, {"text": ".", "start": 394, "end": 395, "id": 74}]}
{"pdf_hash": "1bb331cab519b9ce990ba25ff03132c072bd8a2d", "fig_key": "Figure1", "fig_uri": "7-Figure1-1.png", "text": "Fig 1. The expression of FOXL2 and p53. (a) H&E: The histological findings of aGCTs including small bland cells with the central round nuclei. The typical coffee bean nuclei with nuclear groove is seen. (b) FOXL2 was expressed in the nuclei of GCTs that were heterozygous c.402 C>G mutation. (c) No p53 staining was found in the sample of Pt #1-#4. https://doi.org/10.1371/journal.pone.0178989.g001", "width": 1292, "height": 384, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "c": [61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76]}, "subfigures": [{"id": "975595e1-e97c-47a6-927a-729d754170df", "label": "a", "points": [[6.1, 38.8], [6.1, 345], [422.5, 345], [422.5, 38.8]], "color": "yellow"}, {"id": "b105a0f0-5bec-4d0c-8925-f6540b2e7254", "label": "b", "points": [[449.1, 349], [449.1, 38.8], [861.4, 38.8], [861.4, 349]], "color": "cyan"}, {"id": "8de8384e-e211-4607-9976-e613f26ec4b7", "label": "c", "points": [[873.6, 40.8], [873.6, 349], [1290, 349], [1290, 40.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "1", "start": 4, "end": 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{"pdf_hash": "4b866910f45093c6d94b4e34752fb10d1393091d", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. (A) Computed tomography scanning demonstrated a 1.2x1.7x1.0-cm nodular soft tissue lesion with uniform density at the distal stomach (arrow), and gastric stromal tumor was considered in case 3. (B) Hematoxylin and eosin staining of gastric body gland mucosal under x50 magnification. 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{"pdf_hash": "afa58f9a5a161a5b7502ec8394d85756e1db29c5", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. Chest pain CT coronary in a 50-year-old male patient with acute atypical chest pain presenting to the emergency department. (A) Short axis and (B) 4-chamber reformations revealed transmural hypodense myocardium (black arrow) in the septal and anterior wall of the mid and apical left ventricle. (C) Axial and (D) oblique reformations revealed the corresponding culprit lesion with a soft plaque with slight positive remodeling (arrow) and thrombus occluding the left anterior descending artery. 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{"pdf_hash": "989bc09cf0bbc080c8597dc2d1df34907c585f4a", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Serial CT findings of a dog infected with P. westermani. A. At 30 days, subpleural (long black arrow) and peribronchial nodules (short black arrows in A C) are seen. A small amount of pneumothorax (white arrows in A C) is also seen. B. At 60 days, the size of the subpleural nodule is increased and the peribronchial nodules show cavitary change. C. At 90 days, the size of the subpleural nodule is increased. The cavitary change disappeared in the peribronchial nodule. Note the newly appeared nodule in the right lung (arrowhead). 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{"pdf_hash": "94c16e8df6e227fec62c071d74348dfd3001eeab", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "Figure 6 Typical imaging appearances of HCC. In cirrhotic liver, HCC (arrows) typically (a) demonstrates hyperenhancement in the arterial phase of low molecular weight Gd contrast-enhanced imaging; (b) appears relatively hypointense to liver in the portovenous or interstitial phase of contrast enhancement (washout) and (c) shows impeded diffusion on diffusion-weighted imaging (b \u00bc 500 s mm \u00c02 ).", "width": 1292, "height": 1330, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "c": [57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76]}, "subfigures": [{"id": "656f6aa1-d265-4fed-8f2b-bf4671a7d487", "label": "a", "points": [[63.3, 18.4], [63.3, 681.7], [620.5, 681.7], [620.5, 18.4]], "color": "yellow"}, {"id": "b7c06f49-8f32-438f-b35a-6f99ad891226", "label": "b", "points": [[696, 649.1], [696, 46.9], [1265.5, 46.9], [1265.5, 649.1]], "color": "cyan"}, {"id": 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{"pdf_hash": "25c0e40b6dbf694c95950fd915ec8deb4cffd4d0", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig. 5. A 59-year-old female patient fell down and sustained an unstable L1 bursting fracture. A, B, C, D : Preoperative simple radiographs, computed tomography scans demon-strate about 50% canal encroachment, 26\u00b0 of kyphotic deformity and 60% loss of anterior vertebral height. E : The collapsed vertebra was re-expanded dramatically with postural reduction using a soft roll. 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{"pdf_hash": "964b4dc3899c00f3e9b8ed3f1af3ed0900f55b5d", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3. Case 3. (A) The T1\u2011weighted soft\u2011tissue mass was wide and large at the base of the anterior cranial fossa, and the surrounding tissues were extensively destroyed. (B) T2\u2011weighted signal imaging occurred in the mass. (C) The solid components of the tumor were significantly enhanced.", "width": 1410, "height": 470, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "c": [45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57]}, "subfigures": [{"id": "1363bb36-6aa6-44e7-884a-b4a216098618", "label": "a", "points": [[22.9, 1.9], [22.9, 456.3], [452.8, 456.3], [452.8, 1.9]], "color": "yellow"}, {"id": "0fb5f05d-1787-405d-ac80-6835e25ef0d3", "label": "b", "points": [[492.9, 1.9], [492.9, 449.6], [927.2, 449.6], [927.2, 1.9]], "color": "cyan"}, {"id": "1e0a4825-9c75-498c-9c74-4ae274791d09", "label": "c", "points": [[985.2, 10.8], [985.2, 429.6], [1399.5, 429.6], [1399.5, 10.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Case", "start": 10, "end": 14, "id": 3}, {"text": "3", "start": 15, "end": 16, "id": 4}, {"text": ".", "start": 16, "end": 17, "id": 5}, {"text": "(", "start": 18, "end": 19, "id": 6}, {"text": "A", "start": 19, "end": 20, "id": 7}, {"text": ")", "start": 20, "end": 21, "id": 8}, {"text": "The", "start": 22, "end": 25, "id": 9}, {"text": "T1\u2011weighted", "start": 26, "end": 37, "id": 10}, {"text": "soft\u2011tissue", "start": 38, "end": 49, "id": 11}, {"text": "mass", "start": 50, "end": 54, "id": 12}, {"text": "was", "start": 55, "end": 58, "id": 13}, {"text": "wide", "start": 59, "end": 63, "id": 14}, {"text": "and", "start": 64, "end": 67, "id": 15}, {"text": "large", "start": 68, "end": 73, "id": 16}, {"text": "at", "start": 74, "end": 76, "id": 17}, {"text": "the", "start": 77, "end": 80, "id": 18}, {"text": "base", "start": 81, "end": 85, "id": 19}, {"text": "of", "start": 86, "end": 88, "id": 20}, {"text": "the", "start": 89, "end": 92, "id": 21}, {"text": "anterior", "start": 93, "end": 101, "id": 22}, {"text": "cranial", "start": 102, "end": 109, "id": 23}, {"text": "fossa", "start": 110, "end": 115, "id": 24}, {"text": ",", "start": 115, "end": 116, "id": 25}, {"text": "and", "start": 117, "end": 120, "id": 26}, {"text": "the", "start": 121, "end": 124, "id": 27}, {"text": "surrounding", "start": 125, "end": 136, "id": 28}, {"text": "tissues", "start": 137, "end": 144, "id": 29}, {"text": "were", "start": 145, "end": 149, "id": 30}, {"text": "extensively", "start": 150, "end": 161, "id": 31}, {"text": "destroyed", "start": 162, "end": 171, "id": 32}, {"text": ".", "start": 171, "end": 172, "id": 33}, {"text": "(", "start": 173, "end": 174, "id": 34}, {"text": "B", "start": 174, "end": 175, "id": 35}, {"text": ")", "start": 175, "end": 176, "id": 36}, {"text": "T2\u2011weighted", "start": 177, "end": 188, "id": 37}, {"text": "signal", "start": 189, "end": 195, "id": 38}, {"text": "imaging", "start": 196, "end": 203, "id": 39}, {"text": "occurred", "start": 204, "end": 212, "id": 40}, {"text": "in", "start": 213, "end": 215, "id": 41}, {"text": "the", "start": 216, "end": 219, "id": 42}, {"text": "mass", "start": 220, "end": 224, "id": 43}, {"text": ".", "start": 224, "end": 225, "id": 44}, {"text": "(", "start": 226, "end": 227, "id": 45}, {"text": "C", "start": 227, "end": 228, "id": 46}, {"text": ")", "start": 228, "end": 229, "id": 47}, {"text": "The", "start": 230, "end": 233, "id": 48}, {"text": "solid", "start": 234, "end": 239, "id": 49}, {"text": "components", "start": 240, "end": 250, "id": 50}, {"text": "of", "start": 251, "end": 253, "id": 51}, {"text": "the", "start": 254, "end": 257, "id": 52}, {"text": "tumor", "start": 258, "end": 263, "id": 53}, {"text": "were", "start": 264, "end": 268, "id": 54}, {"text": "significantly", "start": 269, "end": 282, "id": 55}, {"text": "enhanced", "start": 283, "end": 291, "id": 56}, {"text": ".", "start": 291, "end": 292, "id": 57}]}
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{"pdf_hash": "96eae8154cd9870799190f6e114895bd6e8d3e55", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. CT: (A) coronal venous phase cystic abdomen hypodense lesions with a vague rim enhancement, (B) late venous phase CT the peripherical ring disappears.", "width": 1294, "height": 890, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32]}, "subfigures": [{"id": "b8706d1e-87b2-4568-b07f-63fb74f3616a", "label": "a", "points": [[4.7, 7.9], [4.7, 860.3], [599.5, 860.3], [599.5, 7.9]], "color": "yellow"}, {"id": "16d8c5dd-a300-48ec-b66b-9f8675d7448d", "label": "b", "points": [[617.9, 14], [617.9, 862.3], [1253.6, 862.3], [1253.6, 14]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": ":", "start": 12, "end": 13, "id": 4}, {"text": "(", "start": 14, "end": 15, "id": 5}, {"text": "A", "start": 15, "end": 16, "id": 6}, {"text": ")", "start": 16, "end": 17, "id": 7}, {"text": "coronal", "start": 18, "end": 25, "id": 8}, {"text": "venous", "start": 26, "end": 32, "id": 9}, {"text": "phase", "start": 33, "end": 38, "id": 10}, {"text": "cystic", "start": 39, "end": 45, "id": 11}, {"text": "abdomen", "start": 46, "end": 53, "id": 12}, {"text": "hypodense", "start": 54, "end": 63, "id": 13}, {"text": "lesions", "start": 64, "end": 71, "id": 14}, {"text": "with", "start": 72, "end": 76, "id": 15}, {"text": "a", "start": 77, "end": 78, "id": 16}, {"text": "vague", "start": 79, "end": 84, "id": 17}, {"text": "rim", "start": 85, "end": 88, "id": 18}, {"text": "enhancement", "start": 89, "end": 100, "id": 19}, {"text": ",", "start": 100, "end": 101, "id": 20}, {"text": "(", "start": 102, "end": 103, "id": 21}, {"text": "B", "start": 103, "end": 104, "id": 22}, {"text": ")", "start": 104, "end": 105, "id": 23}, {"text": "late", "start": 106, "end": 110, "id": 24}, {"text": "venous", "start": 111, "end": 117, "id": 25}, {"text": "phase", "start": 118, "end": 123, "id": 26}, {"text": "CT", "start": 124, "end": 126, "id": 27}, {"text": "the", "start": 127, "end": 130, "id": 28}, {"text": "peripherical", "start": 131, "end": 143, "id": 29}, {"text": "ring", "start": 144, "end": 148, "id": 30}, {"text": "disappears", "start": 149, "end": 159, "id": 31}, {"text": ".", "start": 159, "end": 160, "id": 32}]}
{"pdf_hash": "f322a64347aeeaea816c1179116e6694160356ae", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. MRI brain demonstrating metastases to brain. Axial (a) and coronal (b) views of the brain demonstrating the presence of brain metastasis.", "width": 576, "height": 348, "subcaptions": {"a": [10, 11, 12, 13], "b": [15, 16, 17, 18]}, "subfigures": [{"id": "0d490b9d-7e45-4707-a713-54c7edf51448", "label": "a", "points": [[6, 2.8], [6, 342.8], [285, 342.8], [285, 2.8]], "color": "yellow"}, {"id": "b02e6547-bf48-4634-ab4f-46396d5add04", "label": "b", "points": [[295, 7.8], [295, 338.8], [571, 338.8], [571, 7.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "MRI", "start": 10, "end": 13, "id": 3}, {"text": "brain", "start": 14, "end": 19, "id": 4}, {"text": "demonstrating", "start": 20, "end": 33, "id": 5}, {"text": "metastases", "start": 34, "end": 44, "id": 6}, {"text": "to", "start": 45, "end": 47, "id": 7}, {"text": "brain", "start": 48, "end": 53, "id": 8}, {"text": ".", "start": 53, "end": 54, "id": 9}, {"text": "Axial", "start": 55, "end": 60, "id": 10}, {"text": "(", "start": 61, "end": 62, "id": 11}, {"text": "a", "start": 62, "end": 63, "id": 12}, {"text": ")", "start": 63, "end": 64, "id": 13}, {"text": "and", "start": 65, "end": 68, "id": 14}, {"text": "coronal", "start": 69, "end": 76, "id": 15}, {"text": "(", "start": 77, "end": 78, "id": 16}, {"text": "b", "start": 78, "end": 79, "id": 17}, {"text": ")", "start": 79, "end": 80, "id": 18}, {"text": "views", "start": 81, "end": 86, "id": 19}, {"text": "of", "start": 87, "end": 89, "id": 20}, {"text": "the", "start": 90, "end": 93, "id": 21}, {"text": "brain", "start": 94, "end": 99, "id": 22}, {"text": "demonstrating", "start": 100, "end": 113, "id": 23}, {"text": "the", "start": 114, "end": 117, "id": 24}, {"text": "presence", "start": 118, "end": 126, "id": 25}, {"text": "of", "start": 127, "end": 129, "id": 26}, {"text": "brain", "start": 130, "end": 135, "id": 27}, {"text": "metastasis", "start": 136, "end": 146, "id": 28}, {"text": ".", "start": 146, "end": 147, "id": 29}]}
{"pdf_hash": "70757f8cda1042aaa0a01348c0ee1bec1b3e21ba", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Pre- and postoperative magnetic resonance imaging showing complete resection and no recurrence in 4 years.", "width": 934, "height": 700, "subcaptions": {"a": [3], "b": [5]}, "subfigures": [{"id": "96f48426-c4e6-46cb-a14a-b10327cbfda6", "label": "a", "points": [[169, 39.6], [169, 364.2], [800.5, 364.2], [800.5, 39.6]], "color": "yellow"}, {"id": "dad61a3f-5e74-4ca1-86e4-fad1fa700840", "label": "b", "points": [[173.4, 374.5], [173.4, 696.2], [801.9, 696.2], [801.9, 374.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Pre-", "start": 7, "end": 11, "id": 3}, {"text": "and", "start": 12, "end": 15, "id": 4}, {"text": "postoperative", "start": 16, "end": 29, "id": 5}, {"text": "magnetic", "start": 30, "end": 38, "id": 6}, {"text": "resonance", "start": 39, "end": 48, "id": 7}, {"text": "imaging", "start": 49, "end": 56, "id": 8}, {"text": "showing", "start": 57, "end": 64, "id": 9}, {"text": "complete", "start": 65, "end": 73, "id": 10}, {"text": "resection", "start": 74, "end": 83, "id": 11}, {"text": "and", "start": 84, "end": 87, "id": 12}, {"text": "no", "start": 88, "end": 90, "id": 13}, {"text": "recurrence", "start": 91, "end": 101, "id": 14}, {"text": "in", "start": 102, "end": 104, "id": 15}, {"text": "4", "start": 105, "end": 106, "id": 16}, {"text": "years", "start": 107, "end": 112, "id": 17}, {"text": ".", "start": 112, "end": 113, "id": 18}]}
{"pdf_hash": "9eb88ab7dc0c3e2f32060c876bef1c489fd88499", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Figure 3 Example of a patient with focal neoplasia (high-grade intraepithelial neoplasia) in a short Barrett oesophagus (upper left) treated by endoscopic mucosal resection (upper middle), followed by argon plasma coagulation. Following dilatation, no residual Barrett could be found including negative biopsies on 5 follow-up endoscopies. 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{"pdf_hash": "75a99962ea0a65412f985f3eed91823a29420776", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3 Immunohistochemical analysis of p53 protein in skin tumors of hairless XPA-de\u00aecient mice. (a) Papilloma, showing a linear staining pattern in the basal cell layer. (b) SCC, in which linear staining, similar to that observed in papillomas, is apparent. (c) SCC, predominantly negative for p53 staining, but harboring a patch of strongly positive nuclei. (d) SCC, showing besides linear pattern of basal cells, extensive nuclear staining for p53 in mainly dysplastic cells. 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{"pdf_hash": "ab4e898c44576a348917f6427ef35a13fd39d2bd", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig 1. Sugarcane smut. (A) Scan electron microscopy of S. scitamineum hyphal growth in the sugarcane bud at 5 DAI (1, 2). Fungal sporogenesis and teliospore maturation in the base of the sugarcane whip at 200 DAI (3; 4). Bar = 10 \u03bcm. (B) (1) Sugarcane bud at 5 DAI. (2) Base of the whip at 200 DAI. 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{"pdf_hash": "e2b87cf72a447c0c7f6f9939fffd1c0f02e8b863", "fig_key": "Figure5", "fig_uri": "13-Figure5-1.png", "text": "Fig. 5. Visualization of a voxel-based statistical analysis. In comparison to the vigilance task, the binding potential (BP) of [ 11 C] FLB 457 decreased during the working-memory task bilaterally in the ventrolateral frontal cortex (panels A-C) and in the left medial-temporal lobe (panel D). Compared to restingstate baseline, both the vigilance (panel E) and the working-memory task (panel F) induced a decrease in the BP of [ 11 C] FLB 457 in the left ventral anterior cingulate gyrus. The results are visualized on a brain model (upper panels) and on an average MRI template image (lower panels). Adapted from Aalto et al. 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{"pdf_hash": "f68a794a1d7a8c9e0266851e9543450d70e16bb4", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Case 3. Preoperative T1-weighted post contrast sagittal magnetic resonance imaging shows an extra-axial enhancing mass centered in the falx cerebri (A). This lesion extended bilaterally with invasion of the anterior and mid superior sagittal sinus. Anteroposterior view of left external carotid artery arteriogram showing multiple arterial feeders to the tumor, mainly from the left middle meningeal artery (B). Anteroposterior view of post-embolization left common carotid artery arteriogram (C).", "width": 1336, "height": 510, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "b": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72], "c": [73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87]}, "subfigures": [{"id": "e9e0671c-05d8-4bc4-ad3b-81b8d2710a87", "label": "a", "points": [[15.4, 1.8], [15.4, 478.8], [433.3, 478.8], [433.3, 1.8]], "color": "yellow"}, {"id": "f12538e4-05c6-4c8c-89e6-d84a58579fa6", "label": "b", "points": [[454.4, 1.8], [454.4, 483], [884.9, 483], [884.9, 1.8]], "color": "cyan"}, {"id": "467bb618-e04a-48e6-be1e-739268444042", "label": "c", "points": [[891.3, 1.8], [891.3, 485.2], [1321.8, 485.2], [1321.8, 1.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, 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{"pdf_hash": "b18735ad1255afb94017353bab2ced83e8c07e95", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Magnetic resonance imaging (MRI) findings of patient no. 1. (A) Preoperative MRI showing osteochondral lesion on medial talar dome. (B, C) Eightmonth postoperative MRI revealing tract traversed by bone drilling and evidence of bone edema on medial malleolus. 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{"pdf_hash": "bd1679733fa375dd1df135cf0ae3b9d90d13acb5", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 A 50-year-old male patient presented with kyphosis due to destructive tubercular spondylodiscitis at T8\u20139 with paravertebral abscess (a\u2013e). After the anterior approach with derbridement, this large defect that occurred after a sagittal profile reconstruction and posterior instrumentation was bridged with a titanium cage and autologous bone grafting (f, g). 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{"pdf_hash": "fe9887b6003dcd980b53c49d6aff7ea1d25629c0", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Axial, (B) coronal and (C) sagittal T1\u2011weighted images captured 3 years prior to the palpable mass of the cervical spine. (D) The coronal view, Gd\u2011DTPA\u2011enhanced image, showing soft\u2011tissue expansion and the destruction of the adjacent normal tissues, including the right side of the processus transversus, lamina and spinous process. (E) The fat-suppressed image discloses a tumor lesion, and compression of the right side of the spinal cord. (F) The sagittal T1-weighted image demonstrates that the nerve root was being squeezed (white arrow). 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{"pdf_hash": "6ed41efce6e3541c35b24565aee15ad62ba1ec48", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Chest radiograph and computed tomograph taken 40 days after the start of treatment showa diffuse reticulonodular infiltrate in both lungs.", "width": 1376, "height": 706, "subcaptions": {"a": [3, 4], "b": [6, 7]}, "subfigures": [{"id": "89e443bf-6398-4f0e-ba58-0bf87158993a", "label": "a", "points": [[5.5, -0.4], [5.5, 699.6], [659.8, 699.6], [659.8, -0.4]], "color": "yellow"}, {"id": "aa6e743f-e94c-43b7-86c5-4b87cef4c049", "label": "b", "points": [[701.1, 4], [701.1, 495.2], [1364.1, 495.2], [1364.1, 4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Chest", "start": 10, "end": 15, "id": 3}, {"text": "radiograph", "start": 16, "end": 26, "id": 4}, {"text": "and", "start": 27, "end": 30, "id": 5}, {"text": "computed", "start": 31, "end": 39, "id": 6}, {"text": "tomograph", "start": 40, "end": 49, "id": 7}, {"text": "taken", "start": 50, "end": 55, "id": 8}, {"text": "40", "start": 56, "end": 58, "id": 9}, {"text": "days", "start": 59, "end": 63, "id": 10}, {"text": "after", "start": 64, "end": 69, "id": 11}, {"text": "the", "start": 70, "end": 73, "id": 12}, {"text": "start", "start": 74, "end": 79, "id": 13}, {"text": "of", "start": 80, "end": 82, "id": 14}, {"text": "treatment", "start": 83, "end": 92, "id": 15}, {"text": "showa", "start": 93, "end": 98, "id": 16}, {"text": "diffuse", "start": 99, "end": 106, "id": 17}, {"text": "reticulonodular", "start": 107, "end": 122, "id": 18}, {"text": "infiltrate", "start": 123, "end": 133, "id": 19}, {"text": "in", "start": 134, "end": 136, "id": 20}, {"text": "both", "start": 137, "end": 141, "id": 21}, {"text": "lungs", "start": 142, "end": 147, "id": 22}, {"text": ".", "start": 147, "end": 148, "id": 23}]}
{"pdf_hash": "34db602bd2ca5ed451b89fd0508efb61bd8ecf4d", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "FIG. 3. CT scan of patient 2 before and after therapy with GM-CSF-induced VPLN cells. Top: Two pulmonary nodules present before therapy (circles). Bottom : Complete regression of these nodules. This patient also had complete regression of a mediastinal lymph node involved with tumor (not shown).", "width": 936, "height": 730, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "bc3f092a-eb60-42e7-b43d-1a56fd2c603f", "label": "a", "points": [[108.7, 14.5], [108.7, 342.8], [819.9, 342.8], [819.9, 14.5]], "color": "yellow"}, {"id": "15f19659-4ddf-4098-a1aa-3ac9da4e3222", "label": "b", "points": [[107.3, 362], [107.3, 708], [825.9, 708], [825.9, 362]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "CT", "start": 8, "end": 10, "id": 4}, {"text": "scan", "start": 11, "end": 15, "id": 5}, {"text": "of", "start": 16, "end": 18, "id": 6}, {"text": "patient", "start": 19, "end": 26, "id": 7}, {"text": "2", "start": 27, "end": 28, "id": 8}, {"text": "before", "start": 29, "end": 35, "id": 9}, {"text": "and", "start": 36, "end": 39, "id": 10}, {"text": "after", "start": 40, "end": 45, "id": 11}, {"text": "therapy", "start": 46, "end": 53, "id": 12}, {"text": "with", "start": 54, "end": 58, "id": 13}, {"text": "GM", "start": 59, "end": 61, "id": 14}, {"text": "-", "start": 61, "end": 62, "id": 15}, {"text": "CSF", "start": 62, "end": 65, "id": 16}, {"text": "-", "start": 65, "end": 66, "id": 17}, {"text": "induced", "start": 66, "end": 73, "id": 18}, {"text": "VPLN", "start": 74, "end": 78, "id": 19}, {"text": "cells", "start": 79, "end": 84, "id": 20}, {"text": ".", "start": 84, "end": 85, "id": 21}, {"text": "Top", "start": 86, "end": 89, "id": 22}, {"text": ":", "start": 89, "end": 90, "id": 23}, {"text": "Two", "start": 91, "end": 94, "id": 24}, {"text": "pulmonary", "start": 95, "end": 104, "id": 25}, {"text": "nodules", "start": 105, "end": 112, "id": 26}, {"text": "present", "start": 113, "end": 120, "id": 27}, {"text": "before", "start": 121, "end": 127, "id": 28}, {"text": "therapy", "start": 128, "end": 135, "id": 29}, {"text": "(", "start": 136, "end": 137, "id": 30}, {"text": "circles", "start": 137, "end": 144, "id": 31}, {"text": ")", "start": 144, "end": 145, "id": 32}, {"text": ".", "start": 145, "end": 146, "id": 33}, {"text": "Bottom", "start": 147, "end": 153, "id": 34}, {"text": ":", "start": 154, "end": 155, "id": 35}, {"text": "Complete", "start": 156, "end": 164, "id": 36}, {"text": "regression", "start": 165, "end": 175, "id": 37}, {"text": "of", "start": 176, "end": 178, "id": 38}, {"text": "these", "start": 179, "end": 184, "id": 39}, {"text": "nodules", "start": 185, "end": 192, "id": 40}, {"text": ".", "start": 192, "end": 193, "id": 41}, {"text": "This", "start": 194, "end": 198, "id": 42}, {"text": "patient", "start": 199, "end": 206, "id": 43}, {"text": "also", "start": 207, "end": 211, "id": 44}, {"text": "had", "start": 212, "end": 215, "id": 45}, {"text": "complete", "start": 216, "end": 224, "id": 46}, {"text": "regression", "start": 225, "end": 235, "id": 47}, {"text": "of", "start": 236, "end": 238, "id": 48}, {"text": "a", "start": 239, "end": 240, "id": 49}, {"text": "mediastinal", "start": 241, "end": 252, "id": 50}, {"text": "lymph", "start": 253, "end": 258, "id": 51}, {"text": "node", "start": 259, "end": 263, "id": 52}, {"text": "involved", "start": 264, "end": 272, "id": 53}, {"text": "with", "start": 273, "end": 277, "id": 54}, {"text": "tumor", "start": 278, "end": 283, "id": 55}, {"text": "(", "start": 284, "end": 285, "id": 56}, {"text": "not", "start": 285, "end": 288, "id": 57}, {"text": "shown", "start": 289, "end": 294, "id": 58}, {"text": ")", "start": 294, "end": 295, "id": 59}, {"text": ".", "start": 295, "end": 296, "id": 60}]}
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{"pdf_hash": "c147f05c4c00de63a50f6ad3ce2975f95536f3f4", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Patient was presented with cystic thoracolumbar lesion (A). Sagittal T2-weighted magnetic resonance imaging (MRI) (B), (C) show the stalk, cerebrospinal fluid (CSF)-filled sac and the bony septum below the stalk level. Coronal T2-weighted MRI (D) and axial computed tomography (CT) scan (E) show bony septum which divides the spinal cord into the 2 hemicords. After the removal of meningocele sac and laminectomy, the bony septum and the stalk became visible (F). The bony septum was removed and the stalk was cut. Proximal spinal cord and both hemicords are now untethered (G). 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{"pdf_hash": "d555131fe706f30e3eb3331084ca774f0c5e9d98", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Subsequent preoperative MR sagittal images showing a rupture of the intervertebral disc (A) and axial images showing PLC and extruded disc mildly compressing the left L5 nerve root (B). MR = magnetic resonance, PLC = posterior ligament complex.", "width": 1056, "height": 678, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "a17bae45-3f86-4f12-acb5-183ced108764", "label": "a", "points": [[27, 22.2], [27, 642.9], [402.3, 642.9], [402.3, 22.2]], "color": "yellow"}, {"id": "91dc90b6-5dd7-426a-95fb-27be210baf2d", "label": "b", "points": [[440.7, 23.9], [440.7, 641.2], [1026.3, 641.2], [1026.3, 23.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Subsequent", "start": 10, "end": 20, "id": 3}, {"text": "preoperative", "start": 21, "end": 33, "id": 4}, {"text": "MR", "start": 34, "end": 36, "id": 5}, {"text": "sagittal", "start": 37, "end": 45, "id": 6}, {"text": "images", "start": 46, "end": 52, "id": 7}, {"text": "showing", "start": 53, "end": 60, "id": 8}, {"text": "a", "start": 61, "end": 62, "id": 9}, {"text": "rupture", "start": 63, "end": 70, "id": 10}, {"text": "of", "start": 71, "end": 73, "id": 11}, {"text": "the", "start": 74, "end": 77, "id": 12}, {"text": "intervertebral", "start": 78, "end": 92, "id": 13}, {"text": "disc", "start": 93, "end": 97, "id": 14}, {"text": "(", "start": 98, "end": 99, "id": 15}, {"text": "A", "start": 99, "end": 100, "id": 16}, {"text": ")", "start": 100, "end": 101, "id": 17}, {"text": "and", "start": 102, "end": 105, "id": 18}, {"text": "axial", "start": 106, "end": 111, "id": 19}, {"text": "images", "start": 112, "end": 118, "id": 20}, {"text": "showing", "start": 119, "end": 126, "id": 21}, {"text": "PLC", "start": 127, "end": 130, "id": 22}, {"text": "and", "start": 131, "end": 134, "id": 23}, {"text": "extruded", "start": 135, "end": 143, "id": 24}, {"text": "disc", "start": 144, "end": 148, "id": 25}, {"text": "mildly", "start": 149, "end": 155, "id": 26}, {"text": "compressing", "start": 156, "end": 167, "id": 27}, {"text": "the", "start": 168, "end": 171, "id": 28}, {"text": "left", "start": 172, "end": 176, "id": 29}, {"text": "L5", "start": 177, "end": 179, "id": 30}, {"text": "nerve", "start": 180, "end": 185, "id": 31}, {"text": "root", "start": 186, "end": 190, "id": 32}, {"text": "(", "start": 191, "end": 192, "id": 33}, {"text": "B", "start": 192, "end": 193, "id": 34}, {"text": ")", "start": 193, "end": 194, "id": 35}, {"text": ".", "start": 194, "end": 195, "id": 36}, {"text": "MR", "start": 196, "end": 198, "id": 37}, {"text": "=", "start": 199, "end": 200, "id": 38}, {"text": "magnetic", "start": 201, "end": 209, "id": 39}, {"text": "resonance", "start": 210, "end": 219, "id": 40}, {"text": ",", "start": 219, "end": 220, "id": 41}, {"text": "PLC", "start": 221, "end": 224, "id": 42}, {"text": "=", "start": 225, "end": 226, "id": 43}, {"text": "posterior", "start": 227, "end": 236, "id": 44}, {"text": "ligament", "start": 237, "end": 245, "id": 45}, {"text": "complex", "start": 246, "end": 253, "id": 46}, {"text": ".", "start": 253, "end": 254, "id": 47}]}
{"pdf_hash": "4960d307b5664d0f5d178238e71e59fb714777a4", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3: X-ray left hip joint anteroposterior view showing (a) severe avascular necrosis with a saddle shaped head with a large extruded chunk anterolaterally after 2 years fracture neck femur. Range of motion only 60\u00b0 of flexion. Severe pain. Harris hip score is 39. (b) Lateral X-ray showing loss of sphericity and extrusion of head anteriorly. Saddle shaped depression is also seen in the centre. (c) After the safe surgical exposure, the head is dislocated with the hip in external rotation. The central depression area with severe damage is seen. The medial portion of the head and the lateral extruded portion have reasonably good cartilage cover. (d) The central depressed portion is resected as a trapezoidal wedge. Part on left is extruded portion. The inner cut edges reveal bleeding signifying intact vascularity and efficacy of the safe surgical approach in preserving blood circulation. (e) The two portions of the head are coapted, fixed with screws. Reasonable sphericity is achieved. (f) A reasonably spherical profile of the head is created. Trochanter healed without problems. Hip range of motion has increased to 90\u00b0 flexion and 25\u00b0 adduction and abduction each. Rotations were restored minimally after 12 months. At 2 years after surgery, Harris hip score is more than 95. No pain at all and limp is minimal. 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{"pdf_hash": "2c4fb95dfbc19929544400c675f1d04a1e060657", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Fig. 4. An example of a stage III, 43-year-old patient presenting with recurrent syncope episode. (A) magnetic resonance imaging showing a 7 cm-sized \u2018comma\u2019 shaped thrombosis, extending from the inferior vena cava (IVC) intrahepatic portion to the right atrium. (B) The transthoracic echocardiography showing an intracardiac mass with dynamic movement past the tricuspid valve into the right ventricle. (C) Specimen from total abdominal hysterectomy, left salpingo-oophorectomy, and IVC and intracardiac mass removal. (D) One-year follow up showing localized recurrence at right iliac fossa found on abdomen pelvic computed tomography. 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{"pdf_hash": "90c2e563329ebe6f9ecd5e498206a67c766aec1c", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "Figure 6 Electron tomography and 3-D model of endosymbiotic bacteria of Litomosoides chagasfilhoi. A: Tomographic series showing a bacterium in an embryo cell. The bacterium is located in a vacuole (V) near the nucleus (N), and it was possible to observe the outer membrane (OM) and some association with the endoplasmic reticulum (ER) (Bar 5 \u03bcm). B: 3-D model obtained from a tomographic series (yellow: nucleus, green: symbiont outer membrane, light blue: vacuole membrane and pink: endoplasmic reticulum). C: Tomographic series showing a bacterium and the vacuole membrane (V) in close association with the nucleus (N) of the nematode host (Bar 5 \u03bcm). D: Detail of the vacuole (V) and nucleus (N) proximity (Bar 5 \u03bcm). 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{"pdf_hash": "8c0587fcab3e5750483334d8de47dc0c75c52461", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: Characterization of the Lifeact-EGFP transgenic mouse islets. A) Schematic representation of the Lifeact-EGFP transgenic construct. Expression of the Lifeact peptide fused to EGFP is driven by CAG promoter [22]. Islets were isolated from Lifeact-EGFP adult mice and cultured either for 3D imaging or perifusion assays. B) Imaging of native Lifeact-EGFP (green) in live pancreatic islets. On the left, representative maximum intensity projection (MIP) of consecutive optical sections of a pancreatic mouse islet cultured for 12 h in the presence of glucose (16 mM); on the right, a single optical section (Single plane). Lifeact-EGFP signal labels all islet cells with a distribution more pronounced at the cellular edges (arrows) than along the cell faces (arrowheads). This is consistent with the labeling distribution observed in individual b-cells upon Lifeact-EGFP adenoviral infection of isolated mouse islets [29]. C) Representative single plane confocal image of whole-mount immunofluorescence staining of Lifeact-EGFP transgenic mouse islets for Phalloidin in red and Lifeact-EGFP in green. Insets show split channels (green and red) of boxed area; arrows indicate overlapping stainings. D) Representative single plane confocal image of whole-mount immunofluorescence of Lifeact-EGFP transgenic mouse islets for glucagon (Gluca, red) and insulin (Ins, blue), in green Lifeact-EGFP. Hoechst 33342 was used as nuclear counterstain. Insets show split channels of boxed area at higher magnification; stars indicate glucagon-positive cells which are negative for insulin. 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{"pdf_hash": "240a65ad6b6933a176ba99e0d1a87178664b8682", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 Delayed expansion of ASDH. Note: (A) A thin ASDH was evident on CT at 1 hour after trauma. (B) The hematoma thickened at 6 hours after trauma.", "width": 668, "height": 540, "subcaptions": {"a": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "9e5308aa-7ad7-46dd-95d4-a70da266e9c4", "label": "a", "points": [[5.8, 4], [5.8, 259.4], [219, 259.4], [219, 4]], "color": "yellow"}, {"id": "78cf9d5e-587d-4ee4-b3c9-3ac02ffe0640", "label": "a", "points": [[225.3, 4], [225.3, 259.4], [442.7, 259.4], [442.7, 4]], "color": "cyan"}, {"id": "9536900d-b102-4660-a631-9b64126e7513", "label": "a", "points": [[449, 5.1], [449, 261.5], [663.3, 261.5], [663.3, 5.1]], "color": "magenta"}, {"id": "e4c14d3b-d2ea-40a5-89e2-8d73b05911c8", "label": "b", "points": [[3.7, 273.1], [3.7, 534.8], [219, 534.8], [219, 273.1]], "color": "springgreen"}, {"id": "be09017a-1c70-4284-81cb-db5dcdfc549a", "label": "b", "points": [[225.3, 273.1], [225.3, 534.8], [439.5, 534.8], [439.5, 273.1]], "color": "tomato"}, {"id": "4a718f69-25b4-4bb0-80ba-5f1d2560b681", "label": "b", "points": [[445.9, 273.1], [445.9, 534.8], [662.2, 534.8], [662.2, 273.1]], "color": "deepskyblue"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Delayed", "start": 7, "end": 14, "id": 3}, {"text": "expansion", "start": 15, "end": 24, "id": 4}, {"text": "of", "start": 25, "end": 27, "id": 5}, {"text": "ASDH", "start": 28, "end": 32, "id": 6}, {"text": ".", "start": 32, "end": 33, "id": 7}, {"text": "Note", "start": 34, "end": 38, "id": 8}, {"text": ":", "start": 38, "end": 39, "id": 9}, {"text": "(", "start": 40, "end": 41, "id": 10}, {"text": "A", "start": 41, "end": 42, "id": 11}, {"text": ")", "start": 42, "end": 43, "id": 12}, {"text": "A", "start": 44, "end": 45, "id": 13}, {"text": "thin", "start": 46, "end": 50, "id": 14}, {"text": "ASDH", "start": 51, "end": 55, "id": 15}, {"text": "was", "start": 56, "end": 59, "id": 16}, {"text": "evident", "start": 60, "end": 67, "id": 17}, {"text": "on", "start": 68, "end": 70, "id": 18}, {"text": "CT", "start": 71, "end": 73, "id": 19}, {"text": "at", "start": 74, "end": 76, "id": 20}, {"text": "1", "start": 77, "end": 78, "id": 21}, {"text": "hour", "start": 79, "end": 83, "id": 22}, {"text": "after", "start": 84, "end": 89, "id": 23}, {"text": "trauma", "start": 90, "end": 96, "id": 24}, {"text": ".", "start": 96, "end": 97, "id": 25}, {"text": "(", "start": 98, "end": 99, "id": 26}, {"text": "B", "start": 99, "end": 100, "id": 27}, {"text": ")", "start": 100, "end": 101, "id": 28}, {"text": "The", "start": 102, "end": 105, "id": 29}, {"text": "hematoma", "start": 106, "end": 114, "id": 30}, {"text": "thickened", "start": 115, "end": 124, "id": 31}, {"text": "at", "start": 125, "end": 127, "id": 32}, {"text": "6", "start": 128, "end": 129, "id": 33}, {"text": "hours", "start": 130, "end": 135, "id": 34}, {"text": "after", "start": 136, "end": 141, "id": 35}, {"text": "trauma", "start": 142, "end": 148, "id": 36}, {"text": ".", "start": 148, "end": 149, "id": 37}]}
{"pdf_hash": "78d73a646bf0904c1a30c20c92ab26dc6f993d9f", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Figure 4 Ultrastructural disease correlates with response to ERT. (a) Myocytes with early Stage 1 or 2 ultrastructural disease predominate in the baseline biopsy of patient A, a good histologic responder. Most cells are full of intact myofibrils with lysosomal glycogen tucked in between (4500 \u00c2 ). (b) Myocytes with late Stage 3 or 4 ultrastructural disease predominate in the baseline biopsy of patient C, a poor histologic responder. Most cells lack myofibrillar structure and are filled with glycogen lakes and debris ( \u00c2 4500). (c) High-power view of the variation in cell damage ( \u00c2 6500). The upper cell with early Stage 2 disease consists of many intact contractile elements with fraying at the fibril ends and peripheral, membrane-bound glycogen (broken arrow). The lower cell with Stage 4 disease has been completely replaced by cytoplasmic glycogen (solid arrow). Ruptured lysosomal membranes float freely in the lake of glycogen. No contractile elements or mitochondria remain. (d) High-power view of a cell with early Stage 2 disease demonstrates abnormally shaped mitochondria and cytoplasmic glycogen beginning to accumulate between contractile elements ( \u00c2 8500). (e) Satellite cells (red arrow) can be seen, by electron microscopy, beneath the basement membrane adjacent to damaged myocytes (black asterix; EM, \u00c2 10 500). (f) All satellite cells, active and quiescent, express m-cadherin (red cell membrane staining, yellow arrows) but only activated satellite cells express myogenin (green nuclear staining, white arrow). A blue nuclear dye was used as a counterstain for all nuclei. 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{"pdf_hash": "86100de4837b0c4ee9c81b9f6e62dcc1d7982436", "fig_key": "Figure18", "fig_uri": "15-Figure18-1.png", "text": "Fig. 18 The superposed CT\u2013PET images for slices 150, 160, and 170 (first row), images of the complementary clusters for slices 150, 160, and 170, treated with imageJ to show edges (second row)", "width": 1016, "height": 588, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "e5332bc6-83fc-42ab-9707-a85ef74d9ea0", "label": "a", "points": [[0.3, 6.4], [0.3, 295.3], [332.5, 295.3], [332.5, 6.4]], "color": "yellow"}, {"id": "30a6edf5-e9fe-4c34-bf0b-977a3a37d296", "label": "b", "points": [[8.3, 301.8], [8.3, 582.6], [332.5, 582.6], [332.5, 301.8]], "color": "cyan"}, {"id": "faf2a35f-1155-4751-894a-d6430f653c85", "label": "b", "points": [[347, 303.4], [347, 584.3], [676, 584.3], [676, 303.4]], "color": "magenta"}, {"id": "31b1720a-4dc1-4d54-b10e-cc392adee49d", "label": "b", "points": [[685.6, 301.8], [685.6, 582.6], [1013.1, 582.6], [1013.1, 301.8]], "color": "springgreen"}, {"id": "e8cb7c0c-c2fc-4a01-ab86-f70e651f3e44", "label": "a", "points": [[340.5, 4.8], [340.5, 288.9], [674.4, 288.9], [674.4, 4.8]], "color": "tomato"}, {"id": "2c4e7622-8e7d-4be9-9f41-a1b2d1f03f6a", "label": "a", "points": [[685.6, 1.6], [685.6, 290.5], [1013.1, 290.5], [1013.1, 1.6]], "color": "deepskyblue"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "18", "start": 5, "end": 7, "id": 2}, {"text": "The", "start": 8, "end": 11, "id": 3}, {"text": "superposed", "start": 12, "end": 22, "id": 4}, {"text": "CT", "start": 23, "end": 25, "id": 5}, {"text": "\u2013", "start": 25, "end": 26, "id": 6}, {"text": "PET", "start": 26, "end": 29, "id": 7}, {"text": "images", "start": 30, "end": 36, "id": 8}, {"text": "for", "start": 37, "end": 40, "id": 9}, {"text": "slices", "start": 41, "end": 47, "id": 10}, {"text": "150", "start": 48, "end": 51, "id": 11}, {"text": ",", "start": 51, "end": 52, "id": 12}, {"text": "160", "start": 53, "end": 56, "id": 13}, {"text": ",", "start": 56, "end": 57, "id": 14}, {"text": "and", "start": 58, "end": 61, "id": 15}, {"text": "170", "start": 62, "end": 65, "id": 16}, {"text": "(", "start": 66, "end": 67, "id": 17}, {"text": "first", "start": 67, "end": 72, "id": 18}, {"text": "row", "start": 73, "end": 76, "id": 19}, {"text": ")", "start": 76, "end": 77, "id": 20}, {"text": ",", "start": 77, "end": 78, "id": 21}, {"text": "images", "start": 79, "end": 85, "id": 22}, {"text": "of", "start": 86, "end": 88, "id": 23}, {"text": "the", "start": 89, "end": 92, "id": 24}, {"text": "complementary", "start": 93, "end": 106, "id": 25}, {"text": "clusters", "start": 107, "end": 115, "id": 26}, {"text": "for", "start": 116, "end": 119, "id": 27}, {"text": "slices", "start": 120, "end": 126, "id": 28}, {"text": "150", "start": 127, "end": 130, "id": 29}, {"text": ",", "start": 130, "end": 131, "id": 30}, {"text": "160", "start": 132, "end": 135, "id": 31}, {"text": ",", "start": 135, "end": 136, "id": 32}, {"text": "and", "start": 137, "end": 140, "id": 33}, {"text": "170", "start": 141, "end": 144, "id": 34}, {"text": ",", "start": 144, "end": 145, "id": 35}, {"text": "treated", "start": 146, "end": 153, "id": 36}, {"text": "with", "start": 154, "end": 158, "id": 37}, {"text": "imageJ", "start": 159, "end": 165, "id": 38}, {"text": "to", "start": 166, "end": 168, "id": 39}, {"text": "show", "start": 169, "end": 173, "id": 40}, {"text": "edges", "start": 174, "end": 179, "id": 41}, {"text": "(", "start": 180, "end": 181, "id": 42}, {"text": "second", "start": 181, "end": 187, "id": 43}, {"text": "row", "start": 188, "end": 191, "id": 44}, {"text": ")", "start": 191, "end": 192, "id": 45}]}
{"pdf_hash": "3f91595822929ec0976df4db2b3d2f94ca34c83e", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Multiplanar reconstruction of the cardiac CT (ECG-triggered mid-diastolic recording). (A) Two-chamber view of the left ventricle and the left atrium. (B) Four-chamber view. (C) Short-axis view. Imaging shows a spherical space (white arrows) adjacent to the basal lateral wall of the left ventricle (diameter 5.5 \u00c2 3.1 \u00c2 5.0 cm). There is slight contrast medium enhancement in this space. The space can be anatomically localized outside the myocardium and appears not to be connected to the pericardium (asterisks), thus being bordered by the epicardium. 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{"pdf_hash": "87afdef96141ffe1765ec17c1aa79038685421bd", "fig_key": "Figure8", "fig_uri": "11-Figure8-1.png", "text": "Figure 8. The imaging and edge detection result of complex area1. (a) Original image; (b) edge detection result of the original image; (c) edge-enhanced SAR image; (d) edge detection result of the edge-enhanced SAR image.", "width": 1202, "height": 498, "subcaptions": {"a": [13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "c": [30, 31, 32, 33, 34, 35, 36, 37, 38], "d": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52]}, "subfigures": [{"id": "57ebbe6f-d54a-40ce-a98a-4b8eff099a5b", "label": "a", "points": [[5.7, 9.5], [5.7, 417.8], [273.4, 417.8], [273.4, 9.5]], "color": "yellow"}, {"id": "7e750d43-2c4a-4d76-9447-043a147df7ed", "label": "b", "points": [[307.6, 3.8], [307.6, 421.6], [584.9, 421.6], [584.9, 3.8]], "color": "cyan"}, {"id": "411813eb-a71a-4d69-aa92-d58cb624d7c6", "label": "c", "points": [[619.1, 419.7], [619.1, 7.6], [894.4, 7.6], [894.4, 419.7]], "color": "magenta"}, {"id": "28bde830-9580-4e34-8523-bbda3a3dbb1e", "label": "d", "points": [[919.1, 3.8], [919.1, 419.7], [1200.1, 419.7], [1200.1, 3.8]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "8", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "The", "start": 10, "end": 13, "id": 3}, {"text": "imaging", "start": 14, "end": 21, "id": 4}, {"text": "and", "start": 22, "end": 25, "id": 5}, {"text": "edge", "start": 26, "end": 30, "id": 6}, {"text": "detection", "start": 31, "end": 40, "id": 7}, {"text": "result", "start": 41, "end": 47, "id": 8}, {"text": "of", "start": 48, "end": 50, "id": 9}, {"text": "complex", "start": 51, "end": 58, "id": 10}, {"text": "area1", "start": 59, "end": 64, "id": 11}, {"text": ".", "start": 64, "end": 65, "id": 12}, {"text": "(", "start": 66, "end": 67, "id": 13}, {"text": "a", "start": 67, "end": 68, "id": 14}, {"text": ")", "start": 68, "end": 69, "id": 15}, {"text": "Original", "start": 70, "end": 78, "id": 16}, {"text": "image", "start": 79, "end": 84, "id": 17}, {"text": ";", "start": 84, "end": 85, "id": 18}, {"text": "(", "start": 86, "end": 87, "id": 19}, {"text": "b", "start": 87, "end": 88, "id": 20}, {"text": ")", "start": 88, "end": 89, "id": 21}, {"text": "edge", "start": 90, "end": 94, "id": 22}, {"text": "detection", "start": 95, "end": 104, "id": 23}, {"text": "result", "start": 105, "end": 111, "id": 24}, {"text": "of", "start": 112, "end": 114, "id": 25}, {"text": "the", "start": 115, "end": 118, "id": 26}, {"text": "original", "start": 119, "end": 127, "id": 27}, {"text": "image", "start": 128, "end": 133, "id": 28}, {"text": ";", "start": 133, "end": 134, "id": 29}, {"text": "(", "start": 135, "end": 136, "id": 30}, {"text": "c", "start": 136, "end": 137, "id": 31}, {"text": ")", "start": 137, "end": 138, "id": 32}, {"text": "edge", "start": 139, "end": 143, "id": 33}, {"text": "-", "start": 143, "end": 144, "id": 34}, {"text": "enhanced", "start": 144, "end": 152, "id": 35}, {"text": "SAR", "start": 153, "end": 156, "id": 36}, {"text": "image", "start": 157, "end": 162, "id": 37}, {"text": ";", "start": 162, "end": 163, "id": 38}, {"text": "(", "start": 164, "end": 165, "id": 39}, {"text": "d", "start": 165, "end": 166, "id": 40}, {"text": ")", "start": 166, "end": 167, "id": 41}, {"text": "edge", "start": 168, "end": 172, "id": 42}, {"text": "detection", "start": 173, "end": 182, "id": 43}, {"text": "result", "start": 183, "end": 189, "id": 44}, {"text": "of", "start": 190, "end": 192, "id": 45}, {"text": "the", "start": 193, "end": 196, "id": 46}, {"text": "edge", "start": 197, "end": 201, "id": 47}, {"text": "-", "start": 201, "end": 202, "id": 48}, {"text": "enhanced", "start": 202, "end": 210, "id": 49}, {"text": "SAR", "start": 211, "end": 214, "id": 50}, {"text": "image", "start": 215, "end": 220, "id": 51}, {"text": ".", "start": 220, "end": 221, "id": 52}]}
{"pdf_hash": "e18276008e5a762c31c5d67ba03af9e193e0aad8", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 Results of soft tissue x ray examination of the hind paw of AA rats. The swelling in the paw was assessed by soft tissue x ray examination on day 21 as described in \u2018\u2018Materials and methods\u2019\u2019. 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{"pdf_hash": "70dd50718e77054909901347b7524d0d0464fac6", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 (left). Chest radiograph taken in October 1972 , in Case 1, showing a \"butterfly\" pattern concentrated about the hilus.", "width": 940, "height": 482, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [0]}, "subfigures": [{"id": "c47e2159-1a92-450c-a363-bae4f297206f", "label": "a", "points": [[36.4, 5.7], [36.4, 449.7], [458.2, 449.7], [458.2, 5.7]], "color": "yellow"}, {"id": "2ced48be-43ec-4166-8a3f-28194eceb98a", "label": "b", "points": [[468.6, 8.7], [468.6, 452.7], [908.1, 452.7], [908.1, 8.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "(", "start": 7, "end": 8, "id": 3}, {"text": "left", "start": 8, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": ".", "start": 13, "end": 14, "id": 6}, {"text": "Chest", "start": 15, "end": 20, "id": 7}, {"text": "radiograph", "start": 21, "end": 31, "id": 8}, {"text": "taken", "start": 32, "end": 37, "id": 9}, {"text": "in", "start": 38, "end": 40, "id": 10}, {"text": "October", "start": 41, "end": 48, "id": 11}, {"text": "1972", "start": 49, "end": 53, "id": 12}, {"text": ",", "start": 54, "end": 55, "id": 13}, {"text": "in", "start": 56, "end": 58, "id": 14}, {"text": "Case", "start": 59, "end": 63, "id": 15}, {"text": "1", "start": 64, "end": 65, "id": 16}, {"text": ",", "start": 65, "end": 66, "id": 17}, {"text": "showing", "start": 67, "end": 74, "id": 18}, {"text": "a", "start": 75, "end": 76, "id": 19}, {"text": "\"", "start": 77, "end": 78, "id": 20}, {"text": "butterfly", "start": 78, "end": 87, "id": 21}, {"text": "\"", "start": 87, "end": 88, "id": 22}, {"text": "pattern", "start": 89, "end": 96, "id": 23}, {"text": "concentrated", "start": 97, "end": 109, "id": 24}, {"text": "about", "start": 110, "end": 115, "id": 25}, {"text": "the", "start": 116, "end": 119, "id": 26}, {"text": "hilus", "start": 120, "end": 125, "id": 27}, {"text": ".", "start": 125, "end": 126, "id": 28}]}
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{"pdf_hash": "50ea60931f36d646275a5784e653ed53bd61044a", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Gastrointestinal endoscopy and colonoscopy. A: The gastric polyps were massive and bled easily. B: Hematoxylin and Eosin (H&E) staining of the gastric polyps. Foveolar hyperplasia and small round cells were observed (lymphocyte>plasma cell). The gastric foveola showed an increased complexity of structure and density. C: Multiple polyps were located throughout the colon. D: H&E staining of the colon polyps. 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{"pdf_hash": "4b8d0ced05aa664387e75c452ce27b9da212a210", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4 (A) Peroperative placement of the osseomyocutaneous flap fixed to the premanufactured reconstruction plate and placed in the exact preplanned position at the recipient site. (B) The virtual preplanned position of the fibula graft. (C) Postoperative cone beam CT showing the accuracy of the fibula placement in accordance with the virtually preplanned position.", "width": 1066, "height": 1096, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "c": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "d": [0]}, "subfigures": [{"id": "9b837eac-ad96-4daa-8124-08687b64fd84", "label": "a", "points": [[39.6, 33.4], [39.6, 333.1], [499.4, 333.1], [499.4, 33.4]], "color": "yellow"}, {"id": "a29b86b4-8d76-4788-bc1e-c7c38bbe6f26", "label": "b", "points": [[41.3, 392.1], [41.3, 701.9], [501, 701.9], [501, 392.1]], "color": "cyan"}, {"id": "8e7913d4-bd27-4b62-bca9-e86160679008", "label": "c", "points": [[39.6, 756.6], [39.6, 1059.8], [497.7, 1059.8], [497.7, 756.6]], "color": "magenta"}, {"id": "6de89ccc-5468-46de-847b-feab5a107c0e", "label": "d", "points": [[548.2, 208.5], [548.2, 941], [1031.5, 941], [1031.5, 208.5]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Peroperative", "start": 13, "end": 25, "id": 5}, {"text": "placement", "start": 26, "end": 35, "id": 6}, {"text": "of", "start": 36, "end": 38, "id": 7}, {"text": "the", "start": 39, "end": 42, "id": 8}, {"text": "osseomyocutaneous", "start": 43, "end": 60, "id": 9}, {"text": "flap", "start": 61, "end": 65, "id": 10}, {"text": "fixed", "start": 66, "end": 71, "id": 11}, {"text": "to", "start": 72, "end": 74, "id": 12}, {"text": "the", "start": 75, "end": 78, "id": 13}, {"text": "premanufactured", "start": 79, "end": 94, "id": 14}, {"text": "reconstruction", "start": 95, "end": 109, "id": 15}, {"text": "plate", "start": 110, "end": 115, "id": 16}, {"text": "and", "start": 116, "end": 119, "id": 17}, {"text": "placed", "start": 120, "end": 126, "id": 18}, {"text": "in", "start": 127, "end": 129, "id": 19}, {"text": "the", "start": 130, "end": 133, "id": 20}, {"text": "exact", "start": 134, "end": 139, "id": 21}, {"text": "preplanned", "start": 140, "end": 150, "id": 22}, {"text": "position", "start": 151, "end": 159, "id": 23}, {"text": "at", "start": 160, "end": 162, "id": 24}, {"text": "the", "start": 163, "end": 166, "id": 25}, {"text": "recipient", "start": 167, "end": 176, "id": 26}, {"text": "site", "start": 177, "end": 181, "id": 27}, {"text": ".", "start": 181, "end": 182, "id": 28}, {"text": "(", "start": 183, "end": 184, "id": 29}, {"text": "B", "start": 184, "end": 185, "id": 30}, {"text": ")", "start": 185, "end": 186, "id": 31}, {"text": "The", "start": 187, "end": 190, "id": 32}, {"text": "virtual", "start": 191, "end": 198, "id": 33}, {"text": "preplanned", "start": 199, "end": 209, "id": 34}, {"text": "position", "start": 210, "end": 218, "id": 35}, {"text": "of", "start": 219, "end": 221, "id": 36}, {"text": "the", "start": 222, "end": 225, "id": 37}, {"text": "fibula", "start": 226, "end": 232, "id": 38}, {"text": "graft", "start": 233, "end": 238, "id": 39}, {"text": ".", "start": 238, "end": 239, "id": 40}, {"text": "(", "start": 240, "end": 241, "id": 41}, {"text": "C", "start": 241, "end": 242, "id": 42}, {"text": ")", "start": 242, "end": 243, "id": 43}, {"text": "Postoperative", "start": 244, "end": 257, "id": 44}, {"text": "cone", "start": 258, "end": 262, "id": 45}, {"text": "beam", "start": 263, "end": 267, "id": 46}, {"text": "CT", "start": 268, "end": 270, "id": 47}, {"text": "showing", "start": 271, "end": 278, "id": 48}, {"text": "the", "start": 279, "end": 282, "id": 49}, {"text": "accuracy", "start": 283, "end": 291, "id": 50}, {"text": "of", "start": 292, "end": 294, "id": 51}, {"text": "the", "start": 295, "end": 298, "id": 52}, {"text": "fibula", "start": 299, "end": 305, "id": 53}, {"text": "placement", "start": 306, "end": 315, "id": 54}, {"text": "in", "start": 316, "end": 318, "id": 55}, {"text": "accordance", "start": 319, "end": 329, "id": 56}, {"text": "with", "start": 330, "end": 334, "id": 57}, {"text": "the", "start": 335, "end": 338, "id": 58}, {"text": "virtually", "start": 339, "end": 348, "id": 59}, {"text": "preplanned", "start": 349, "end": 359, "id": 60}, {"text": "position", "start": 360, "end": 368, "id": 61}, {"text": ".", "start": 368, "end": 369, "id": 62}]}
{"pdf_hash": "52044f07b1e785243a63d6807275589c45e703d3", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 Images of Case 8. A: A computed tomogram (CT) at admission showing a right acute subdural hematoma with a mid-line shift. B: A single photon emission CT on Day 0 demonstrating a decrease in blood flow in the right hemisphere. C: A CT performed 6 hours after admission and immediately after hematoma removal. No apparent abnormality is demonstrated in the brain parenchyma and the mid-line shift improves. D: A CT on Day 2 showing no apparent cerebral infarction. E: A magnetic resonance (MR) image/fluid-attenuated inversion recovery (FLAIR) on Day 4 showing high intensity lesions in the right frontal lobe, right basal ganglia, right occipital lobe, and the left frontal lobe. The cerebral infarction associates with brain swelling. 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{"pdf_hash": "fc5a8098ec82c4b6a303cafd309cbd72408fa005", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. Mucosal injury of the small intestine during capsule endoscopy. a: Petechiae b: Denuded area was defined as reddened area without villi.", "width": 1232, "height": 572, "subcaptions": {"a": [14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "bb7679f7-98a1-459b-b388-46249a5c5095", "label": "a", "points": [[67.2, 3.6], [67.2, 534.9], [590.7, 534.9], [590.7, 3.6]], "color": "yellow"}, {"id": "c8a1335c-ff82-4710-b020-34fb18fdcb39", "label": "b", "points": [[664.7, 3.6], [664.7, 542.7], [1198, 542.7], [1198, 3.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Mucosal", "start": 8, "end": 15, "id": 4}, {"text": "injury", "start": 16, "end": 22, "id": 5}, {"text": "of", "start": 23, "end": 25, "id": 6}, {"text": "the", "start": 26, "end": 29, "id": 7}, {"text": "small", "start": 30, "end": 35, "id": 8}, {"text": "intestine", "start": 36, "end": 45, "id": 9}, {"text": "during", "start": 46, "end": 52, "id": 10}, {"text": "capsule", "start": 53, "end": 60, "id": 11}, {"text": "endoscopy", "start": 61, "end": 70, "id": 12}, {"text": ".", "start": 70, "end": 71, "id": 13}, {"text": "a", "start": 72, "end": 73, "id": 14}, {"text": ":", "start": 73, "end": 74, "id": 15}, {"text": "Petechiae", "start": 75, "end": 84, "id": 16}, {"text": "b", "start": 85, "end": 86, "id": 17}, {"text": ":", "start": 86, "end": 87, "id": 18}, {"text": "Denuded", "start": 88, "end": 95, "id": 19}, {"text": "area", "start": 96, "end": 100, "id": 20}, {"text": "was", "start": 101, "end": 104, "id": 21}, {"text": "defined", "start": 105, "end": 112, "id": 22}, {"text": "as", "start": 113, "end": 115, "id": 23}, {"text": "reddened", "start": 116, "end": 124, "id": 24}, {"text": "area", "start": 125, "end": 129, "id": 25}, {"text": "without", "start": 130, "end": 137, "id": 26}, {"text": "villi", "start": 138, "end": 143, "id": 27}, {"text": ".", "start": 143, "end": 144, "id": 28}]}
{"pdf_hash": "dc15dec008a25bcb6c1b91fa1d484186c4d3425d", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Representative 4.7 tesla in vivo MRI images of control (N-AL) mice on E18.5. Respiratory-gated spin-echo images were collected following intraperitoneal administration of the contrast agent. Transaxial image of murine placentas (A; arrows) and coronal image of murine fetuses (B; arrows) are shown. Enhancement of the chorionic plate preceded enhancement of the remainder of the placental parenchyma and occurred within 30 s of contrast agent injection in all 3 experimental groups.", "width": 570, "height": 1226, "subcaptions": {"a": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "b": [50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "4a67d49b-fafb-48e7-b4a1-20559c6b9328", "label": "a", "points": [[28.5, 4], [28.5, 503], [536.5, 503], [536.5, 4]], "color": "yellow"}, {"id": "5d23927d-22cb-46b8-ac75-dc655d4d5831", "label": "b", "points": [[28.5, 520], [28.5, 1191], [533.5, 1191], [533.5, 520]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Representative", "start": 8, "end": 22, "id": 4}, {"text": "4.7", "start": 23, "end": 26, "id": 5}, {"text": "tesla", "start": 27, "end": 32, "id": 6}, {"text": 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{"pdf_hash": "3ab1e9ab56ca991cc9f083f3424cc3855bed3b93", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 a 47-year-old male with a PTMC lesion in whom conventional ultrasound examination showed a 7.8 mm\u00d7 6.8 mm\u00d7 4.3 mm hypoechoic nodule. b After PLA, CEUS revealed a hypoechoic area in the original area, along with some debris in the centre that presented as strong echoes, which demonstrated that the lesion had been completely ablated. c Six months after PLA, conventional ultrasound examination showed a 7.1 mm\u00d7 3.2 mm\u00d7 2.1 mm hyperechoic nodule. d Eighteen months after PLA, conventional ultrasound examination showed that the lesion had completely disappeared", "width": 1010, "height": 792, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 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{"pdf_hash": "b3148027edc0a1aecde57aab57ee1c1827071ef4", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 Chest images at current admission. (A) Chest X-ray shows left pleural effusion; (B) chest CT shows left pleural effusion and mild cardiomegaly.", "width": 1088, "height": 520, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "a4b45a0a-e765-41da-a8bb-5e42ae2cc15a", "label": "a", "points": [[35.3, 3.2], [35.3, 487.8], [533.7, 487.8], [533.7, 3.2]], "color": "yellow"}, {"id": "fb1a1c7d-6bfa-4602-b79a-cce46ae2f904", "label": "b", "points": [[550.9, 6.6], [550.9, 486.1], [1059.6, 486.1], [1059.6, 6.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "Chest", "start": 9, "end": 14, "id": 2}, {"text": "images", "start": 15, "end": 21, "id": 3}, {"text": "at", "start": 22, "end": 24, "id": 4}, {"text": "current", "start": 25, "end": 32, "id": 5}, {"text": "admission", "start": 33, "end": 42, "id": 6}, {"text": ".", "start": 42, "end": 43, "id": 7}, {"text": "(", "start": 44, "end": 45, "id": 8}, {"text": "A", "start": 45, "end": 46, "id": 9}, {"text": ")", "start": 46, "end": 47, "id": 10}, {"text": "Chest", "start": 48, "end": 53, "id": 11}, {"text": "X", "start": 54, "end": 55, "id": 12}, {"text": "-", "start": 55, "end": 56, "id": 13}, {"text": "ray", "start": 56, "end": 59, "id": 14}, {"text": "shows", "start": 60, "end": 65, "id": 15}, {"text": "left", "start": 66, "end": 70, "id": 16}, {"text": "pleural", "start": 71, "end": 78, "id": 17}, {"text": "effusion", "start": 79, "end": 87, "id": 18}, {"text": ";", "start": 87, "end": 88, "id": 19}, {"text": "(", "start": 89, "end": 90, "id": 20}, {"text": "B", "start": 90, "end": 91, "id": 21}, {"text": ")", "start": 91, "end": 92, "id": 22}, {"text": "chest", "start": 93, "end": 98, "id": 23}, {"text": "CT", "start": 99, "end": 101, "id": 24}, {"text": "shows", "start": 102, "end": 107, "id": 25}, {"text": "left", "start": 108, "end": 112, "id": 26}, {"text": "pleural", "start": 113, "end": 120, "id": 27}, {"text": "effusion", "start": 121, "end": 129, "id": 28}, {"text": "and", "start": 130, "end": 133, "id": 29}, {"text": "mild", "start": 134, "end": 138, "id": 30}, {"text": "cardiomegaly", "start": 139, "end": 151, "id": 31}, {"text": ".", "start": 151, "end": 152, "id": 32}]}
{"pdf_hash": "b0df2d0c3725f98aaf4f63c55f424b3d9d297ae7", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 The huge abdominal mass shows mild 18F-FDG uptake on a the anterior maximum intensity projection image and b the coronal and c the axial PET/CT fusion image. d The axial PET/CT fusion image shows ascites (top arrow) and a right-sided pleural effusion (bottom arrow) without significant 18F-FDG uptake", "width": 1182, "height": 654, "subcaptions": {"a": [34, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [32, 33, 34, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 22, 23, 24, 29, 30, 31], "c": [32, 33, 34, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 26, 27, 28, 29, 30, 31], "d": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65]}, "subfigures": [{"id": "669af976-b42b-4c84-bce5-c8d0d3426b14", "label": "a", "points": [[14.1, 3.4], [14.1, 619.6], [365.1, 619.6], [365.1, 3.4]], "color": "yellow"}, {"id": "f5cf2e10-6c87-469f-93af-1c72d7d8addb", "label": "b", "points": [[380.1, -0.3], [380.1, 617.7], [648.9, 617.7], [648.9, -0.3]], "color": "cyan"}, {"id": "fb954020-9a6b-47cd-be33-3bb21ce63e49", "label": "c", "points": [[663.9, -0.3], [663.9, 307.8], [1175.5, 307.8], [1175.5, -0.3]], "color": "magenta"}, {"id": "be5472ee-64dd-4fce-9bbf-779297779635", "label": "d", "points": [[660.1, 328.3], [660.1, 619.6], [1177.4, 619.6], [1177.4, 328.3]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "The", "start": 7, "end": 10, "id": 3}, {"text": "huge", "start": 11, "end": 15, "id": 4}, {"text": "abdominal", "start": 16, "end": 25, "id": 5}, {"text": "mass", "start": 26, "end": 30, "id": 6}, {"text": "shows", "start": 31, "end": 36, "id": 7}, {"text": "mild", "start": 37, "end": 41, "id": 8}, {"text": "18F", "start": 42, "end": 45, "id": 9}, {"text": "-", "start": 45, "end": 46, "id": 10}, {"text": "FDG", "start": 46, "end": 49, "id": 11}, {"text": "uptake", "start": 50, "end": 56, "id": 12}, {"text": "on", "start": 57, "end": 59, "id": 13}, {"text": "a", "start": 60, "end": 61, "id": 14}, {"text": "the", "start": 62, "end": 65, "id": 15}, {"text": "anterior", "start": 66, "end": 74, "id": 16}, {"text": "maximum", "start": 75, "end": 82, "id": 17}, {"text": "intensity", "start": 83, "end": 92, "id": 18}, {"text": "projection", "start": 93, "end": 103, "id": 19}, {"text": "image", "start": 104, "end": 109, "id": 20}, {"text": "and", "start": 110, "end": 113, "id": 21}, {"text": "b", "start": 114, "end": 115, "id": 22}, {"text": "the", "start": 116, "end": 119, "id": 23}, {"text": "coronal", "start": 120, "end": 127, "id": 24}, {"text": "and", "start": 128, "end": 131, "id": 25}, {"text": "c", "start": 132, "end": 133, "id": 26}, {"text": "the", "start": 134, "end": 137, "id": 27}, {"text": "axial", "start": 138, "end": 143, "id": 28}, {"text": "PET", "start": 144, "end": 147, "id": 29}, {"text": "/", "start": 147, "end": 148, "id": 30}, {"text": "CT", "start": 148, "end": 150, "id": 31}, {"text": "fusion", "start": 151, "end": 157, "id": 32}, {"text": "image", "start": 158, "end": 163, "id": 33}, {"text": ".", "start": 163, "end": 164, "id": 34}, {"text": "d", "start": 165, "end": 166, "id": 35}, {"text": "The", "start": 167, "end": 170, "id": 36}, {"text": "axial", "start": 171, "end": 176, "id": 37}, {"text": "PET", "start": 177, "end": 180, "id": 38}, {"text": "/", "start": 180, "end": 181, "id": 39}, {"text": "CT", "start": 181, "end": 183, "id": 40}, {"text": "fusion", "start": 184, "end": 190, "id": 41}, {"text": "image", "start": 191, "end": 196, "id": 42}, {"text": "shows", "start": 197, "end": 202, "id": 43}, {"text": "ascites", "start": 203, "end": 210, "id": 44}, {"text": "(", "start": 211, "end": 212, "id": 45}, {"text": "top", "start": 212, "end": 215, "id": 46}, {"text": "arrow", "start": 216, "end": 221, "id": 47}, {"text": ")", "start": 221, "end": 222, "id": 48}, {"text": "and", "start": 223, "end": 226, "id": 49}, {"text": "a", "start": 227, "end": 228, "id": 50}, {"text": "right", "start": 229, "end": 234, "id": 51}, {"text": "-", "start": 234, "end": 235, "id": 52}, {"text": "sided", "start": 235, "end": 240, "id": 53}, {"text": "pleural", "start": 241, "end": 248, "id": 54}, {"text": "effusion", "start": 249, "end": 257, "id": 55}, {"text": "(", "start": 258, "end": 259, "id": 56}, {"text": "bottom", "start": 259, "end": 265, "id": 57}, {"text": "arrow", "start": 266, "end": 271, "id": 58}, {"text": ")", "start": 271, "end": 272, "id": 59}, {"text": "without", "start": 273, "end": 280, "id": 60}, {"text": "significant", "start": 281, "end": 292, "id": 61}, {"text": "18F", "start": 293, "end": 296, "id": 62}, {"text": "-", "start": 296, "end": 297, "id": 63}, {"text": "FDG", "start": 297, "end": 300, "id": 64}, {"text": "uptake", "start": 301, "end": 307, "id": 65}]}
{"pdf_hash": "649215336d1e098d18cb0c9c9581a2dfca2d3372", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Immunohistochemical detection of RUNX3 expression on tissue samples. The procedure for immunohistochemical staining with anti-RUNX3 monoclonal antibody R3-6E9 was the same as that described by Ito et al. (2005). (a) H&E stain on normal epidermis; (b) corresponding RUNX3 expression in normal epidermis; (c) low-power view of a TMA punch including normal epidermis and BCC in the dermis; (d) high-power view showing a rim on normal epidermis (top) and the nodules of infiltrating BCC with strong, nuclear antibody expression.", "width": 660, "height": 692, "subcaptions": {"a": [40, 41, 42, 43, 44, 45, 46, 47], "b": [49, 50, 51, 52, 53, 54, 55, 56, 57], "c": [59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77], "d": [79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107]}, "subfigures": [{"id": "1a9ddf51-0158-47b3-b126-d23f8a607249", "label": "a", "points": [[3.7, 3], [3.7, 171.9], [655.3, 171.9], [655.3, 3]], "color": "yellow"}, {"id": "3b1e0244-8b98-4c6b-9de9-ea3d38bc762a", "label": "b", "points": [[2.6, 176], [2.6, 328.2], [656.4, 328.2], [656.4, 176]], "color": "cyan"}, {"id": 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{"pdf_hash": "39836e289c30b2c31a24bc4eae342bc5eeeac5c1", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. SPECT imaging Coronal view of SPECT images obtained around the third ventricle in the brain of 17e18 month old tg-ArcSwe mice, 2 h post injection of A. [125I]pF(ab\u2019)2-h158 and B. [125I]F(ab\u2019)2h158. C. Coronal, sagittal and transverse images obtained from the frontal cortical area of the mouse injected with [125I]pF(ab\u2019)2-h158 (same individual as in A). The cross-hair indicates the same position in all three views. 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{"pdf_hash": "bbeddb120988f2d1ecd6ee5b3a08c8516c0bcb00", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Computed tomography (CT) images of the patient who experienced a local recurrence: (A) before treatment, (B) after treatment, and (C) after recurrence. CT image shows intermediate density lesion (arrow) adjacent to the left internal iliac vessels.", "width": 1370, "height": 360, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 37], "b": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 25, 26, 27, 28, 29], "c": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "1175f857-967b-4e2c-b285-67ef137632a2", "label": "a", "points": [[5, 1.9], [5, 352.5], [440, 352.5], [440, 1.9]], "color": "yellow"}, {"id": "7740eda0-d88f-4aab-8bbc-8d3abea1e3ca", "label": "b", "points": [[476.8, 8.4], [476.8, 346], [905.3, 346], [905.3, 8.4]], "color": "cyan"}, {"id": "d207ae69-04e7-4a7a-b0b3-f1858308d203", "label": "c", "points": [[914, 10.5], [914, 359], [1366.3, 359], [1366.3, 10.5]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Computed", "start": 8, "end": 16, "id": 4}, {"text": "tomography", "start": 17, "end": 27, "id": 5}, {"text": "(", "start": 28, "end": 29, "id": 6}, {"text": "CT", "start": 29, "end": 31, "id": 7}, {"text": ")", "start": 31, "end": 32, "id": 8}, {"text": "images", "start": 33, "end": 39, "id": 9}, {"text": "of", "start": 40, "end": 42, "id": 10}, {"text": "the", "start": 43, "end": 46, "id": 11}, {"text": "patient", "start": 47, "end": 54, "id": 12}, {"text": "who", "start": 55, "end": 58, "id": 13}, {"text": "experienced", "start": 59, "end": 70, "id": 14}, {"text": "a", "start": 71, "end": 72, "id": 15}, {"text": "local", "start": 73, "end": 78, "id": 16}, {"text": "recurrence", "start": 79, "end": 89, "id": 17}, {"text": ":", "start": 89, "end": 90, "id": 18}, {"text": "(", "start": 91, "end": 92, "id": 19}, {"text": "A", "start": 92, "end": 93, "id": 20}, {"text": ")", "start": 93, "end": 94, "id": 21}, {"text": "before", "start": 95, "end": 101, "id": 22}, {"text": "treatment", "start": 102, "end": 111, "id": 23}, {"text": ",", "start": 111, "end": 112, "id": 24}, {"text": "(", "start": 113, "end": 114, "id": 25}, {"text": "B", "start": 114, "end": 115, "id": 26}, {"text": ")", "start": 115, "end": 116, "id": 27}, {"text": "after", "start": 117, "end": 122, "id": 28}, {"text": "treatment", "start": 123, "end": 132, "id": 29}, {"text": ",", "start": 132, "end": 133, "id": 30}, {"text": "and", "start": 134, "end": 137, "id": 31}, {"text": "(", "start": 138, "end": 139, "id": 32}, {"text": "C", "start": 139, "end": 140, "id": 33}, {"text": ")", "start": 140, "end": 141, "id": 34}, {"text": "after", "start": 142, "end": 147, "id": 35}, {"text": "recurrence", "start": 148, "end": 158, "id": 36}, {"text": ".", "start": 158, "end": 159, "id": 37}, {"text": "CT", "start": 160, "end": 162, "id": 38}, {"text": "image", "start": 163, "end": 168, "id": 39}, {"text": "shows", "start": 169, "end": 174, "id": 40}, {"text": "intermediate", "start": 175, "end": 187, "id": 41}, {"text": "density", "start": 188, "end": 195, "id": 42}, {"text": "lesion", "start": 196, "end": 202, "id": 43}, {"text": "(", "start": 203, "end": 204, "id": 44}, {"text": "arrow", "start": 204, "end": 209, "id": 45}, {"text": ")", "start": 209, "end": 210, "id": 46}, {"text": "adjacent", "start": 211, "end": 219, "id": 47}, {"text": "to", "start": 220, "end": 222, "id": 48}, {"text": "the", "start": 223, "end": 226, "id": 49}, {"text": "left", "start": 227, "end": 231, "id": 50}, {"text": "internal", "start": 232, "end": 240, "id": 51}, {"text": "iliac", "start": 241, "end": 246, "id": 52}, {"text": "vessels", "start": 247, "end": 254, "id": 53}, {"text": ".", "start": 254, "end": 255, "id": 54}]}
{"pdf_hash": "702e864bf483c86cd30ce8417c3e522092366141", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Avascular osteonecrosis on proximal tibial epiphysis evidenced in rightknee magnetic resonance. Right-knee magnetic resonance images sagittal T2-weighted with fat suppression (A) and sagittal T1-weighted (B) showing bone marrow edema (arrowhead) in proximal tibial epiphysis and a mild line on T1-w image (arrow) suggestive of bone fracture related to avascular osteonecrosis.", "width": 644, "height": 408, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 64], "b": [15, 16, 17, 18, 19, 20, 30, 31, 32, 33, 34, 35, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "aaf6ae3c-0a05-460f-90b1-60014e4425b0", "label": "a", "points": [[3.1, 0], [3.1, 373.4], [313.4, 373.4], [313.4, 0]], "color": "yellow"}, {"id": "9248dc90-875a-4fbb-bf4f-cec34ad2b0f6", "label": "b", "points": [[333.7, 372.4], [333.7, 2], [641, 2], [641, 372.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Avascular", "start": 10, "end": 19, "id": 3}, {"text": "osteonecrosis", "start": 20, "end": 33, "id": 4}, {"text": "on", "start": 34, "end": 36, "id": 5}, {"text": "proximal", "start": 37, "end": 45, "id": 6}, {"text": "tibial", "start": 46, "end": 52, "id": 7}, {"text": "epiphysis", "start": 53, "end": 62, "id": 8}, {"text": "evidenced", "start": 63, "end": 72, "id": 9}, {"text": "in", "start": 73, "end": 75, "id": 10}, {"text": "rightknee", "start": 76, "end": 85, "id": 11}, {"text": "magnetic", "start": 86, "end": 94, "id": 12}, {"text": "resonance", "start": 95, "end": 104, "id": 13}, {"text": ".", "start": 104, "end": 105, "id": 14}, {"text": "Right", "start": 106, "end": 111, "id": 15}, {"text": "-", "start": 111, "end": 112, "id": 16}, {"text": "knee", "start": 112, "end": 116, "id": 17}, {"text": "magnetic", "start": 117, "end": 125, "id": 18}, {"text": "resonance", "start": 126, "end": 135, "id": 19}, {"text": "images", "start": 136, "end": 142, "id": 20}, {"text": "sagittal", "start": 143, "end": 151, "id": 21}, {"text": "T2-weighted", "start": 152, "end": 163, "id": 22}, {"text": "with", "start": 164, "end": 168, "id": 23}, {"text": "fat", "start": 169, "end": 172, "id": 24}, {"text": "suppression", "start": 173, "end": 184, "id": 25}, {"text": "(", "start": 185, "end": 186, "id": 26}, {"text": "A", "start": 186, "end": 187, "id": 27}, {"text": ")", "start": 187, "end": 188, "id": 28}, {"text": "and", "start": 189, "end": 192, "id": 29}, {"text": "sagittal", "start": 193, "end": 201, "id": 30}, {"text": "T1-weighted", "start": 202, "end": 213, "id": 31}, {"text": "(", "start": 214, "end": 215, "id": 32}, {"text": "B", "start": 215, "end": 216, "id": 33}, {"text": ")", "start": 216, "end": 217, "id": 34}, {"text": "showing", "start": 218, "end": 225, "id": 35}, {"text": "bone", "start": 226, "end": 230, "id": 36}, {"text": "marrow", "start": 231, "end": 237, "id": 37}, {"text": "edema", "start": 238, "end": 243, "id": 38}, {"text": "(", "start": 244, "end": 245, "id": 39}, {"text": "arrowhead", "start": 245, "end": 254, "id": 40}, {"text": ")", "start": 254, "end": 255, "id": 41}, {"text": "in", "start": 256, "end": 258, "id": 42}, {"text": "proximal", "start": 259, "end": 267, "id": 43}, {"text": "tibial", "start": 268, "end": 274, "id": 44}, {"text": "epiphysis", "start": 275, "end": 284, "id": 45}, {"text": "and", "start": 285, "end": 288, "id": 46}, {"text": "a", "start": 289, "end": 290, "id": 47}, {"text": "mild", "start": 291, "end": 295, "id": 48}, {"text": "line", "start": 296, "end": 300, "id": 49}, {"text": "on", "start": 301, "end": 303, "id": 50}, {"text": "T1-w", "start": 304, "end": 308, "id": 51}, {"text": "image", "start": 309, "end": 314, "id": 52}, {"text": "(", "start": 315, "end": 316, "id": 53}, {"text": "arrow", "start": 316, "end": 321, "id": 54}, {"text": ")", "start": 321, "end": 322, "id": 55}, {"text": "suggestive", "start": 323, "end": 333, "id": 56}, {"text": "of", "start": 334, "end": 336, "id": 57}, {"text": "bone", "start": 337, "end": 341, "id": 58}, {"text": "fracture", "start": 342, "end": 350, "id": 59}, {"text": "related", "start": 351, "end": 358, "id": 60}, {"text": "to", "start": 359, "end": 361, "id": 61}, {"text": "avascular", "start": 362, "end": 371, "id": 62}, {"text": "osteonecrosis", "start": 372, "end": 385, "id": 63}, {"text": ".", "start": 385, "end": 386, "id": 64}]}
{"pdf_hash": "5e5f8d7e3371edf6b9b4da51fc817d0cdc5d5c2b", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Fig. 6. Dose distributions due to a 130 MeV proton pencil beam in the NCAT-head sphenoid region, superimposed on the corresponding CT axial slices (in gray scale). The proton range is reduced by 14 mm in the case of a filled nasal cavity (right) in comparison to the (planned) situation with an empty nasal cavity (left).", "width": 1064, "height": 556, "subcaptions": {"a": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "b": [58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69]}, "subfigures": [{"id": "e38f64d5-7ea2-4ddc-b150-27d9f2ecd56e", "label": "a", "points": [[527.8, 33.6], [527.8, 433.7], [919.5, 433.7], [919.5, 33.6]], "color": "yellow"}, {"id": "87db8848-baea-4fdb-8284-3cbf614ee4e8", "label": "b", "points": [[517.7, 433.7], [517.7, 42], [79, 42], [79, 433.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "6", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Dose", "start": 8, "end": 12, "id": 4}, {"text": "distributions", "start": 13, "end": 26, "id": 5}, {"text": "due", "start": 27, "end": 30, "id": 6}, {"text": "to", "start": 31, "end": 33, "id": 7}, {"text": "a", "start": 34, "end": 35, "id": 8}, {"text": "130", "start": 36, "end": 39, "id": 9}, {"text": "MeV", "start": 40, "end": 43, "id": 10}, {"text": "proton", "start": 44, "end": 50, "id": 11}, {"text": "pencil", "start": 51, "end": 57, "id": 12}, {"text": "beam", "start": 58, "end": 62, "id": 13}, {"text": "in", "start": 63, "end": 65, "id": 14}, {"text": "the", "start": 66, "end": 69, "id": 15}, {"text": "NCAT", "start": 70, "end": 74, "id": 16}, {"text": "-", "start": 74, "end": 75, "id": 17}, {"text": "head", "start": 75, "end": 79, "id": 18}, {"text": "sphenoid", "start": 80, "end": 88, "id": 19}, {"text": "region", "start": 89, "end": 95, "id": 20}, {"text": ",", "start": 95, "end": 96, "id": 21}, {"text": "superimposed", "start": 97, "end": 109, "id": 22}, {"text": "on", "start": 110, "end": 112, "id": 23}, {"text": "the", "start": 113, "end": 116, "id": 24}, {"text": "corresponding", "start": 117, "end": 130, "id": 25}, {"text": "CT", "start": 131, "end": 133, "id": 26}, {"text": "axial", "start": 134, "end": 139, "id": 27}, {"text": "slices", "start": 140, "end": 146, "id": 28}, {"text": "(", "start": 147, "end": 148, "id": 29}, {"text": "in", "start": 148, "end": 150, "id": 30}, {"text": "gray", "start": 151, "end": 155, "id": 31}, {"text": "scale", "start": 156, "end": 161, "id": 32}, {"text": ")", "start": 161, "end": 162, "id": 33}, {"text": ".", "start": 162, "end": 163, "id": 34}, {"text": "The", "start": 164, "end": 167, "id": 35}, {"text": "proton", "start": 168, "end": 174, "id": 36}, {"text": "range", "start": 175, "end": 180, "id": 37}, {"text": "is", "start": 181, "end": 183, "id": 38}, {"text": "reduced", "start": 184, "end": 191, "id": 39}, {"text": "by", "start": 192, "end": 194, "id": 40}, {"text": "14", "start": 195, "end": 197, "id": 41}, {"text": "mm", "start": 198, "end": 200, "id": 42}, {"text": "in", "start": 201, "end": 203, "id": 43}, {"text": "the", "start": 204, "end": 207, "id": 44}, {"text": "case", "start": 208, "end": 212, "id": 45}, {"text": "of", "start": 213, "end": 215, "id": 46}, {"text": "a", "start": 216, "end": 217, "id": 47}, {"text": "filled", "start": 218, "end": 224, "id": 48}, {"text": "nasal", "start": 225, "end": 230, "id": 49}, {"text": "cavity", "start": 231, "end": 237, "id": 50}, {"text": "(", "start": 238, "end": 239, "id": 51}, {"text": "right", "start": 239, "end": 244, "id": 52}, {"text": ")", "start": 244, "end": 245, "id": 53}, {"text": "in", "start": 246, "end": 248, "id": 54}, {"text": "comparison", "start": 249, "end": 259, "id": 55}, {"text": "to", "start": 260, "end": 262, "id": 56}, {"text": "the", "start": 263, "end": 266, "id": 57}, {"text": "(", "start": 267, "end": 268, "id": 58}, {"text": "planned", "start": 268, "end": 275, "id": 59}, {"text": ")", "start": 275, "end": 276, "id": 60}, {"text": "situation", "start": 277, "end": 286, "id": 61}, {"text": "with", "start": 287, "end": 291, "id": 62}, {"text": "an", "start": 292, "end": 294, "id": 63}, {"text": "empty", "start": 295, "end": 300, "id": 64}, {"text": "nasal", "start": 301, "end": 306, "id": 65}, {"text": "cavity", "start": 307, "end": 313, "id": 66}, {"text": "(", "start": 314, "end": 315, "id": 67}, {"text": "left", "start": 315, "end": 319, "id": 68}, {"text": ")", "start": 319, "end": 320, "id": 69}, {"text": ".", "start": 320, "end": 321, "id": 70}]}
{"pdf_hash": "2ea4271e68f0102816b8268fef38a432b7d992e9", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "FIGURE 1. A 63-year-old female patient with a probably benign mass on conventional breast examinations. MRI showed a lobulated mass in the right breast (A). DCE-MRI showed an indeterminate plateau-type kinetic curve (B). The lesion showed high signal on DWI (C) and a small decrease in signal intensity on ADC map (D), ADC \u00bc 1.50 \u00c2 10 \u00c03 mm 2 /s, suggestive of benign lesion. PET-MRI fusion showed increased 18 F-FDG uptake (E), suggestive of malignant lesion. Percutaneous biopsy was compatible with mucinous carcinoma. 18 F-FDG \u00bc 18 F-fluoro-deoxi-glucose, ADC \u00bc apparent diffusion coefficient, DCE-MRI \u00bc dynamic contrast-enhanced magnetic resonance imaging, DWI \u00bc diffusion-weighted imaging, PET-MRI \u00bc positron emission tomography and magnetic resonance imaging.", "width": 1304, "height": 322, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "c": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "d": [47, 48, 49, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85], "e": [96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95]}, "subfigures": [{"id": "0d87ff0c-b945-4074-a133-3374d49606be", "label": "a", "points": [[25.1, 0.7], [25.1, 297.4], [288.8, 297.4], [288.8, 0.7]], "color": "yellow"}, {"id": "ad4b6956-3de0-4645-b955-b8ad8578ad4a", "label": 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{"pdf_hash": "d91e0feca2362d997d94009f35fde54c8c5d6121", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Intraoperative views of the bony forehead after subperiosteal reflection of the forehead soft tissue using a coronal incision. a Lateral view. Note the severe boosing of the orbital rim with a supraorbital concavity of the forehead. The boosing was reduced by burring down into the diploe until the frontal sinus was shining through before augmentation of the supraorbiatal cavitation. b Lateral view with tremendous thinning of the anterior wall frontal sinus. c Cranial eccentric view", "width": 1360, "height": 398, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65], "b": [66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78], "c": [79, 80, 81, 82]}, "subfigures": [{"id": "ae2a2c9d-5722-4882-8773-1c2f891e2489", "label": "a", "points": [[11.1, 2.9], [11.1, 370.3], [423.6, 370.3], [423.6, 2.9]], "color": "yellow"}, {"id": "e5f5b90e-04cf-460a-a365-bac1aee5053e", "label": "b", "points": [[438.7, 5], [438.7, 374.6], [776, 374.6], [776, 5]], "color": "cyan"}, {"id": "1ba673e7-934c-4aaa-a519-07c0195cec1e", "label": "c", "points": [[797.5, 9.3], [797.5, 355.3], [1347.6, 355.3], 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{"pdf_hash": "1ba20cdc8b9beef1094595dfefe7f808634314b3", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig 3. Comparison of two patients both imaged 1 hour after symptom onset with a proximal occlusion of the middle cerebral artery and a Higashida score of 2 on source DSC MRI. Patient A had a left-sided stroke with NIHSS at admission of 12, an initial infarct volume of 3.8ml, perfusion deficit of 200ml on Tmax4s and 108ml on CBF with a CBF/Tmax4s volume ratio of 0.54. The final infarct size was 15.5ml. Patient B had a right-sided stroke with NIHSS at admission of 19, an initial infarct volume of 5.8ml, perfusion deficit of 87ml on Tmax4s and 84ml on CBF with a CBF/Tmax4s volume ratio of 0.96. 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{"pdf_hash": "6aa6c3e167220ed233d4c6d21463bddc40a61d81", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Chest computed tomography (CT) before bronchoscopy showed left pleural effusion and nodule shadows in an area adjacent to the descending aorta and directly under the pleura. (B) Chest CT after bronchoscopy showed a decreased amount of left pleural effusion.", "width": 866, "height": 430, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50]}, "subfigures": [{"id": "ec3053dd-f9ca-4677-aec3-420a9e22919b", "label": "a", "points": [[6.2, 3.9], [6.2, 426.6], [424.8, 426.6], [424.8, 3.9]], "color": "yellow"}, {"id": "da71aa74-9c37-431e-b35f-8dd50c977d35", "label": "b", "points": [[441.2, 3.9], [441.2, 426.6], [861.2, 426.6], [861.2, 3.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Chest", "start": 14, "end": 19, "id": 6}, {"text": "computed", "start": 20, "end": 28, "id": 7}, {"text": "tomography", "start": 29, "end": 39, "id": 8}, {"text": "(", "start": 40, "end": 41, "id": 9}, {"text": "CT", "start": 41, "end": 43, "id": 10}, {"text": ")", "start": 43, "end": 44, "id": 11}, {"text": "before", "start": 45, "end": 51, "id": 12}, {"text": "bronchoscopy", "start": 52, "end": 64, "id": 13}, {"text": "showed", "start": 65, "end": 71, "id": 14}, {"text": "left", "start": 72, "end": 76, "id": 15}, {"text": "pleural", "start": 77, "end": 84, "id": 16}, {"text": "effusion", "start": 85, "end": 93, "id": 17}, {"text": "and", "start": 94, "end": 97, "id": 18}, {"text": "nodule", "start": 98, "end": 104, "id": 19}, {"text": "shadows", "start": 105, "end": 112, "id": 20}, {"text": "in", "start": 113, "end": 115, "id": 21}, {"text": "an", "start": 116, "end": 118, "id": 22}, {"text": "area", "start": 119, "end": 123, "id": 23}, {"text": "adjacent", "start": 124, "end": 132, "id": 24}, {"text": "to", "start": 133, "end": 135, "id": 25}, {"text": "the", "start": 136, "end": 139, "id": 26}, {"text": "descending", "start": 140, "end": 150, "id": 27}, {"text": "aorta", "start": 151, "end": 156, "id": 28}, {"text": "and", "start": 157, "end": 160, "id": 29}, {"text": "directly", "start": 161, "end": 169, "id": 30}, {"text": "under", "start": 170, "end": 175, "id": 31}, {"text": "the", "start": 176, "end": 179, "id": 32}, {"text": "pleura", "start": 180, "end": 186, "id": 33}, {"text": ".", "start": 186, "end": 187, "id": 34}, {"text": "(", "start": 188, "end": 189, "id": 35}, {"text": "B", "start": 189, "end": 190, "id": 36}, {"text": ")", "start": 190, "end": 191, "id": 37}, {"text": "Chest", "start": 192, "end": 197, "id": 38}, {"text": "CT", "start": 198, "end": 200, "id": 39}, {"text": "after", "start": 201, "end": 206, "id": 40}, {"text": "bronchoscopy", "start": 207, "end": 219, "id": 41}, {"text": "showed", "start": 220, "end": 226, "id": 42}, {"text": "a", "start": 227, "end": 228, "id": 43}, {"text": "decreased", "start": 229, "end": 238, "id": 44}, {"text": "amount", "start": 239, "end": 245, "id": 45}, {"text": "of", "start": 246, "end": 248, "id": 46}, {"text": "left", "start": 249, "end": 253, "id": 47}, {"text": "pleural", "start": 254, "end": 261, "id": 48}, {"text": "effusion", "start": 262, "end": 270, "id": 49}, {"text": ".", "start": 270, "end": 271, "id": 50}]}
{"pdf_hash": "a781007b2664a302e6a3500d642ae145d186200f", "fig_key": "Figure2", "fig_uri": "1-Figure2-1.png", "text": "Figure 2 Diagnostic images at 48 hours after hospitalisation. (A) CT\u00a0angiography of the neck demonstrating spontaneous recanalisation of the left carotid artery. (B) CT perfusion showing a compatible pattern with cerebral hyperperfusion syndrome, as defined by increased CBV and CBF along with decreased MTT and reduced Tmax. 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{"pdf_hash": "a1ff15181c1bbf9f16d9fe22e5b378189e053d01", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4. Clavicle fracture (white arrows) of the left shoulder on X-ray (a) and on US (b: coronal view, c: sagittal view) with superiorproximal fragment (white star) and distal- inferior fragment (white asterisk). Normal dorsal part of the acromio-clavicular ligament (white arrowheads) on US (d: dorsal view).", "width": 1334, "height": 912, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 22, 23, 24, 25, 26, 27, 28, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "c": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 22, 23, 24, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "d": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72]}, "subfigures": [{"id": "931b7222-17bc-4fdd-8a3a-bfce561dd082", "label": "a", "points": [[11.7, 10.2], [11.7, 442.2], [669.2, 442.2], [669.2, 10.2]], "color": "yellow"}, {"id": "fb7cc92e-1a66-48c0-b749-d58b62bde08a", "label": "b", "points": [[690.2, 3.9], [690.2, 446.4], [1330.9, 446.4], [1330.9, 3.9]], "color": "cyan"}, {"id": "6596f281-4323-417f-8ac1-9c7feedbe9d3", "label": "c", "points": [[11.7, 463.3], [11.7, 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{"pdf_hash": "8f130c4a559ce71921d656eda4041a6271d28d89", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 \u2013 Noncontrast coronal (A) and axial (B) computed tomography demonstrated a cystic mass (red circle) in the left parotid region with no surrounding fat stranding, lymphadenopathy, or bony erosion. No malignant features were demonstrated. The mass measured 8.0 \u00d7 5.2 \u00d7 6.5 cm.", "width": 500, "height": 1058, "subcaptions": {"a": [5, 6, 7, 8], "b": [10, 11, 12, 13]}, "subfigures": [{"id": "5e57d3cf-f71b-4323-82a5-e4dd79dac0ca", "label": "a", "points": [[0, 0.8], [0, 489.9], [491, 489.9], [491, 0.8]], "color": "yellow"}, {"id": "ee8a17a6-0ede-4dd8-8812-8f244c1277d5", "label": "b", "points": [[2, 492.9], [2, 1051.9], [495, 1051.9], [495, 492.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "Noncontrast", "start": 9, "end": 20, "id": 4}, {"text": "coronal", "start": 21, "end": 28, "id": 5}, {"text": "(", "start": 29, "end": 30, "id": 6}, {"text": "A", "start": 30, "end": 31, "id": 7}, {"text": ")", "start": 31, "end": 32, "id": 8}, {"text": "and", "start": 33, "end": 36, "id": 9}, {"text": "axial", "start": 37, "end": 42, "id": 10}, {"text": "(", "start": 43, "end": 44, "id": 11}, {"text": "B", "start": 44, "end": 45, "id": 12}, {"text": ")", "start": 45, "end": 46, "id": 13}, {"text": "computed", "start": 47, "end": 55, "id": 14}, {"text": "tomography", "start": 56, "end": 66, "id": 15}, {"text": "demonstrated", "start": 67, "end": 79, "id": 16}, {"text": "a", "start": 80, "end": 81, "id": 17}, {"text": "cystic", "start": 82, "end": 88, "id": 18}, {"text": "mass", "start": 89, "end": 93, "id": 19}, {"text": "(", "start": 94, "end": 95, "id": 20}, {"text": "red", "start": 95, "end": 98, "id": 21}, {"text": "circle", "start": 99, "end": 105, "id": 22}, {"text": ")", "start": 105, "end": 106, "id": 23}, {"text": "in", "start": 107, "end": 109, "id": 24}, {"text": "the", "start": 110, "end": 113, "id": 25}, {"text": "left", "start": 114, "end": 118, "id": 26}, {"text": "parotid", "start": 119, "end": 126, "id": 27}, {"text": "region", "start": 127, "end": 133, "id": 28}, {"text": "with", "start": 134, "end": 138, "id": 29}, {"text": "no", "start": 139, "end": 141, "id": 30}, {"text": "surrounding", "start": 142, "end": 153, "id": 31}, {"text": "fat", "start": 154, "end": 157, "id": 32}, {"text": "stranding", "start": 158, "end": 167, "id": 33}, {"text": ",", "start": 167, "end": 168, "id": 34}, {"text": "lymphadenopathy", "start": 169, "end": 184, "id": 35}, {"text": ",", "start": 184, "end": 185, "id": 36}, {"text": "or", "start": 186, "end": 188, "id": 37}, {"text": "bony", "start": 189, "end": 193, "id": 38}, {"text": "erosion", "start": 194, "end": 201, "id": 39}, {"text": ".", "start": 201, "end": 202, "id": 40}, {"text": "No", "start": 203, "end": 205, "id": 41}, {"text": "malignant", "start": 206, "end": 215, "id": 42}, {"text": "features", "start": 216, "end": 224, "id": 43}, {"text": "were", "start": 225, "end": 229, "id": 44}, {"text": "demonstrated", "start": 230, "end": 242, "id": 45}, {"text": ".", "start": 242, "end": 243, "id": 46}, {"text": "The", "start": 244, "end": 247, "id": 47}, {"text": "mass", "start": 248, "end": 252, "id": 48}, {"text": "measured", "start": 253, "end": 261, "id": 49}, {"text": "8.0", "start": 262, "end": 265, "id": 50}, {"text": "\u00d7", "start": 266, "end": 267, "id": 51}, {"text": "5.2", "start": 268, "end": 271, "id": 52}, {"text": "\u00d7", "start": 272, "end": 273, "id": 53}, {"text": "6.5", "start": 274, "end": 277, "id": 54}, {"text": "cm", "start": 278, "end": 280, "id": 55}, {"text": ".", "start": 280, "end": 281, "id": 56}]}
{"pdf_hash": "7bc2fe80949bb4758eb12359b8047f620beb04e1", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Serial computed tomography images of the left medial rectus muscle. a Computed tomography scan showing a normal left medial rectus muscle at 6 months before the first ophthalmological visit (Sep 2017). b Computed tomography scan showing enlargement of the left medial rectus muscle at 3 months before the first ophthalmological visit (Dec 2017). c Computed tomography scan of the left medical rectus muscle taken 10 days before the first ophthalmological visit (5 Mar 2018)", "width": 1342, "height": 482, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "c": [63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85]}, "subfigures": [{"id": 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{"pdf_hash": "cf0ca455db838dbc1c2e39c6333a21f845f15025", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Sternum fracture with involvement of the upper manubrium: oblique fracture \u2013 the higher lap belt injury. (A) Often caused by a lap belt injury in smaller car occupants the unstable fractures show severe dislocation with a gap in front of the upper mediastinum and instability of the shoulder girdle (Case 3). Often series of ribs are broken following the direction of the lap belt. (B) The oblique fracture had been stabilized by a transversal plate on the 1st pair of ribs, the adjacent ribs had been treated by costosternal plate (2nd rib) and plating (3rd rib). The second sternal fracture which involved the upper corpus sterni received a longitudinal plate. (C) the sagittal profile has been restored. (D) dislocated oblique manubrium fracture (Case 2). (E) reduction using compression wires (DePuySynthes, Switzerland) (F) fixation with the first of two transverse plates.", "width": 1104, "height": 760, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74], "b": [75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129], "c": [130, 131, 132, 133, 134, 135, 136, 137, 138, 139], "d": [140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151], "e": [152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163], "f": [164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175]}, "subfigures": [{"id": "a09fa187-0cb1-4030-9051-845f640ae33b", "label": "a", "points": [[4.4, 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{"pdf_hash": "96c5295fcb2bf74367fe8bc53166f9eb875906e9", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2: (A) Photograph of the 15-month-old patient with suboptimal cosmetic result caused by left secondary coronal synostosis. (B) Three-dimensional computed tomography scan of the skull demonstrating a new left unilateral coronal synostosis. (C) fast imaging with steady-state free precession (FISP) magnetic resonance imaging of the brain.", "width": 1238, "height": 1694, "subcaptions": {"a": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "1184d928-3af8-40e6-b97c-696ab2f49078", "label": "a", "points": [[5, 29], [5, 490.6], [390.2, 490.6], [390.2, 29]], "color": "yellow"}, {"id": "fa969926-db11-4a6d-8388-d4c2661460c3", "label": "b", "points": [[5, 1010.8], [5, 1667.9], [660.1, 1667.9], [660.1, 1010.8]], "color": "orange"}, {"id": "473cfbeb-ea6b-47f2-a317-6f5bc946745b", "label": "c", "points": [[679.7, 1008.8], [679.7, 1669.8], [1227.3, 1669.8], [1227.3, 1008.8]], "color": "hotpink"}, {"id": "1e5d1b3b-3d89-4746-abb0-13d9b2de34e4", "label": "a", "points": [[423.5, 29], [423.5, 482.7], [814.6, 482.7], [814.6, 29]], "color": "cyan"}, {"id": "bf101749-eaeb-4fc0-8f83-5db4ab3f21b8", "label": "a", "points": [[842, 32.9], [842, 482.7], [1229.2, 482.7], [1229.2, 32.9]], "color": "magenta"}, {"id": "e3290601-8d93-4de7-9b46-3afdefd7c032", "label": "a", "points": [[8.9, 508.2], [8.9, 969.7], [398.1, 969.7], [398.1, 508.2]], "color": "springgreen"}, {"id": "4cd81c44-d649-4ba5-ad20-7aa8d0a6d2c3", "label": "a", "points": [[423.5, 510.1], [423.5, 969.7], [824.4, 969.7], [824.4, 510.1]], "color": "tomato"}, {"id": "2fc864a7-195a-40ec-be57-4304b24bc37b", "label": "a", "points": [[840, 504.2], [840, 967.7], [1223.3, 967.7], [1223.3, 504.2]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Photograph", "start": 14, "end": 24, "id": 6}, {"text": "of", "start": 25, "end": 27, "id": 7}, {"text": "the", "start": 28, "end": 31, "id": 8}, {"text": "15-month", "start": 32, "end": 40, "id": 9}, {"text": "-", "start": 40, "end": 41, "id": 10}, {"text": "old", "start": 41, "end": 44, "id": 11}, {"text": "patient", "start": 45, "end": 52, "id": 12}, {"text": "with", "start": 53, "end": 57, "id": 13}, {"text": "suboptimal", "start": 58, "end": 68, "id": 14}, {"text": "cosmetic", "start": 69, "end": 77, "id": 15}, {"text": "result", "start": 78, "end": 84, "id": 16}, {"text": "caused", "start": 85, "end": 91, "id": 17}, {"text": "by", "start": 92, "end": 94, "id": 18}, {"text": "left", "start": 95, "end": 99, "id": 19}, {"text": "secondary", "start": 100, "end": 109, "id": 20}, {"text": "coronal", "start": 110, "end": 117, "id": 21}, {"text": "synostosis", "start": 118, "end": 128, "id": 22}, {"text": ".", "start": 128, "end": 129, "id": 23}, {"text": "(", "start": 130, "end": 131, "id": 24}, {"text": "B", "start": 131, "end": 132, "id": 25}, {"text": ")", "start": 132, "end": 133, "id": 26}, {"text": "Three", "start": 134, "end": 139, "id": 27}, {"text": "-", "start": 139, "end": 140, "id": 28}, {"text": "dimensional", "start": 140, "end": 151, "id": 29}, {"text": "computed", "start": 152, "end": 160, "id": 30}, {"text": "tomography", "start": 161, "end": 171, "id": 31}, {"text": "scan", "start": 172, "end": 176, "id": 32}, {"text": "of", "start": 177, "end": 179, "id": 33}, {"text": "the", "start": 180, "end": 183, "id": 34}, {"text": "skull", "start": 184, "end": 189, "id": 35}, {"text": "demonstrating", "start": 190, "end": 203, "id": 36}, {"text": "a", "start": 204, "end": 205, "id": 37}, {"text": "new", "start": 206, "end": 209, "id": 38}, {"text": "left", "start": 210, "end": 214, "id": 39}, {"text": "unilateral", "start": 215, "end": 225, "id": 40}, {"text": "coronal", "start": 226, "end": 233, "id": 41}, {"text": "synostosis", "start": 234, "end": 244, "id": 42}, {"text": ".", "start": 244, "end": 245, "id": 43}, {"text": "(", "start": 246, "end": 247, "id": 44}, {"text": "C", "start": 247, "end": 248, "id": 45}, {"text": ")", "start": 248, "end": 249, "id": 46}, {"text": "fast", "start": 250, "end": 254, "id": 47}, {"text": "imaging", "start": 255, "end": 262, "id": 48}, {"text": "with", "start": 263, "end": 267, "id": 49}, {"text": "steady", "start": 268, "end": 274, "id": 50}, {"text": "-", "start": 274, "end": 275, "id": 51}, {"text": "state", "start": 275, "end": 280, "id": 52}, {"text": "free", "start": 281, "end": 285, "id": 53}, {"text": "precession", "start": 286, "end": 296, "id": 54}, {"text": "(", "start": 297, "end": 298, "id": 55}, {"text": "FISP", "start": 298, "end": 302, "id": 56}, {"text": ")", "start": 302, "end": 303, "id": 57}, {"text": "magnetic", "start": 304, "end": 312, "id": 58}, {"text": "resonance", "start": 313, "end": 322, "id": 59}, {"text": "imaging", "start": 323, "end": 330, "id": 60}, {"text": "of", "start": 331, "end": 333, "id": 61}, {"text": "the", "start": 334, "end": 337, "id": 62}, {"text": "brain", "start": 338, "end": 343, "id": 63}, {"text": ".", "start": 343, "end": 344, "id": 64}]}
{"pdf_hash": "2cfb49129085325320e134f83439a13bcb4009df", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2 A flat panel C-arm computerized tomography (CT) is performed. The C-arm CT is then used to select a needle path to the foramen rotundum using needle guidance software, and a lesion depth is calculated (A and B). The needle is then positioned in a bull\u2019s eye approach targeting the selected depth, with a postpositioning CT performed to confirm the needle location prior to treatment, as depicted on this multiplanar reformatted CT image (C). 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{"pdf_hash": "9208278e668c546e678cf527eea400f16e7c6bca", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "FIGURE 4 COG KO Golgi fragmentation phenotype is not related to glycosylation defects. Airyscan super-resolution microscopy of HEK293T and GALE, MGAT1, and COG4 KO cells was used to determine if the Golgi structure (marked by GM130[cis, green] and Rab6 [trans, red]) is affected in MGAT1 and GALE cells. Golgi of WT, MGAT1, and GALE KO cells is not fragmented, while COG4 KO cells demonstrate intense Golgi fragmentation. Nuclear DNA was stained with Hoechst (blue). Scale bar is 10 \u03bcm. 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{"pdf_hash": "7aaa514763c9a564586858d3b34ac81039eea669", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Figure 6. Fiber bundles connecting pairs of clusters of the REST-IC4 component, as assessed by DWI, PAS, and deterministic tractography. For a clearer visualization, the fibers shown were tracked only within an exclusion mask, which was obtained as follows: first, a map, where each voxel value was set to the number of streamlines intersecting it, was computed; then, a sum of this map values over a 3-voxel cubic neighborhood was computed for each voxel; finally, the latter map was thresholded at a value of 15, and the fibers were then tracked. Top: 3D visualization of ICA clusters and connecting fiber bundles; cluster colors: yellow: PPar; red: DLP; green: VLP. Abbreviations as in Table 4. Bottom: Coronal sections showing the location of connecting tracts in the white matter of the left hemisphere. 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{"pdf_hash": "c955018d09b1fca28db2f3fe92c0ad03f17a42ed", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig 2. Positron emission tomographic scan images follozuing \" F - 2-j7uoro-2-deoxy-~g~ucose administration in a typical normal subject (top images) and a typical patient with progressive supranuclear palsy (bottom images). Each is a horizontal section in a plane parallel t o and approximately 4 cm, level A (left images) or 8 cm, level F (right images) above the canthomeatal line. The front of the head is to the top of the inuge and the right of the head i s t o the right of the image. 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{"pdf_hash": "f65dc11e4d467e1c46ebdc6de8a3f99a5786b475", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "FIGURE 5. GRPR PET/CT imaging at 4 h after injection of 64 Cu-CB-TE2A-AR-06 in 2 patients with biopsy-proven prostate cancer. (A-C) Patient with biopsy-proven prostate cancer: coronal sections of PET and fused PET/CT (A and B) and axial PET/CT fusion images at levels indicated by dotted lines in A (C). There is intense uptake by prostate tumor (arrows) and pancreas. (D and E) Correlation between in vivo PET and ex vivo autoradiography in another patient with prostate cancer who underwent surgery after PET/CT: transaxial fused PET/CT (D) and ex vivo GRP autoradiography demonstrating GRPR expression by tumor (E). 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{"pdf_hash": "5a8b3973f18237e996303d9d05f17f040ec60d2c", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Fig. 3. FAPP2 depletion induces morphological changes in the apical lumen of cysts. (A) The transepithelial resistance (TER, graph) was determined in filter-grown cells as described in Materials and Methods. The cells were seeded on polycarbonate filters for 4 days. The black column corresponds to control, and the white column corresponds to KD cells. Data are means \u03ee SE of three separate experiments. (B-E) KD and control cells were suspended in Matrigel and cultured in the matrix for 4 -7 days. The cysts were fixed and processed. Confocal sections passing through the middle of each cyst are shown. Whereas \u03fe60% of the KD cells (C) had formed cysts with a collapsed apical lumen, as visualized by actin staining with TRITC-phalloidin (red) and nuclear staining with DAPI (blue), only 20% of control cells (B) displayed a collapsed lumen. Apical (podocalyxin, red) and basolateral (gp58, green) distribution in control (D) and FAPP2-KD (E) cells is shown. 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{"pdf_hash": "c2449206c1f9ab6e5a080cd98604426a40d93fa3", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. The clinical case is illustrated. (A) Results of brain magnetic resonance imaging (MRI) in T2-weighted sequences performed on June 2013 (1) and on February 2014 after brain biopsy (2), showing global white and gray matter atrophy and periventricular hypersignals. Brain MRI performed on September 2014 (3) showed no progression in brain atrophy or increasing in periventricular hypersignals. (B) Results of brain biopsy showing the following: (1) microglial nodules (arrow) and perivascular infiltrates (arrow heads) in the cortex and white matter (hematoxylin and eosin stain, bar = 100 \u03bcm); (2) IBA1 immunohistochemistry confirming diffuse microglial activation (WAKO rabbit polyclonal anti-IBA1, 1:500) (bar = 100 \u03bcm). Perivascular cuffs of mononuclear cells include T lymphocytes (3) CD3 + (Ventana monoclonal rabbit antibody 1:500) and (4) CD8 + (FLEX ready-to-use monoclonal mouse antibody) (bar = 50 \u03bcm). 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{"pdf_hash": "17663954811e03bd481b5f744ddda06e2026cafa", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "FIG. 4. Spin\u00b7echo images and signal intensity profiles from the cat brain obtained using circumscribing coil (a) and combined circumscribing coil/surface coil (b) arrangements for the superficial Region 1. The data were acquired using a repetition time (TR) of 2 s and spin-echo time (TE) of 71.8 ms for (a) and a TR of 2 s and TE of 23.6 ms for (b). In addition, 128 phase-encoding steps, each with two averages, were acquired. The approximate depth of the lesion for an equivalent slice that was obtained in the image was determined from histological studies following the experiment.", "width": 1338, "height": 1046, "subcaptions": {"a": [4, 5, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 82], "b": [4, 5, 10, 11, 12, 13, 14, 15, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82]}, "subfigures": [{"id": "26724ac8-effc-45c2-9e24-0cf388263d24", "label": "a", "points": [[33.9, 82.1], [33.9, 492.1], [575, 492.1], [575, 82.1]], "color": "yellow"}, {"id": "322c3074-bd1a-4feb-9b3b-9a420ea95184", "label": "b", "points": [[25.4, 513.3], [25.4, 944.4], [583.4, 944.4], [583.4, 513.3]], "color": "magenta"}, {"id": "bc67c44f-d0ba-42dd-8e29-eb158d820823", "label": "c", "points": [[594, 8.1], 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{"pdf_hash": "e60b73b887a2b808041d66d28abd0cdbba25c672", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "FIGURE 5 PEG sections in stage 23 chick embryo, Hamburger and Hamilton (4 d of incubation [32]). Ng-CAM and NC-1 epitope immunolabeling. Sections in A and D are stained with rabbit anti-Ng-CAM IgG; in B and E they are stained with NC-1; in C and F they are seen by phase contrast. (A-C) Views of the same transverse section at the 15th somite level. NC-1 (B) reacts with the dorsal root and sympathetic ganglion rudiment. Ng-CAM (A) is still found as a thin band on the ventral side of the neural tube and on all motor neuron fibers. The dorsal root and sympathetic cells are devoid of Ng-CAM, a few fibers ascending to the dorsal root ganglion are visible. (D-F) Views of the same section in rhombencephalon: the first fibers emerging from the metencephalon are stained for Ng-CAM (D). A similar pattern is obtained with NC-1 (E). Note however, that more cell bodies are stained with the latter, ao, aorta; drg, dorsal root ganglion; my, myotome; n, notochord; nt, neural tube; sg, sympathetic ganglion. Bar, 40/~m. 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{"pdf_hash": "93be2e6df9d39cce7fac369c8d4313d800e797c1", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 A 57-year-old man referred for workup of a solitary pulmonary mass (patient 5). FDG-PET/CT images showed a right subpleural consolidation with the rim sign (a, axial PET; b, axial fusion, arrow). MDCT confirmed acute pulmonary embolism (c, arrow) showing an adjacent subsegmental pulmonary embolism. Note the absence of any suggestive signs of pulmonary infarction on MDCT. 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{"pdf_hash": "55da8c898d5c2ee03b5005656feab2ab97dd18e0", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4: PET scan of the brain showing no hypermetabolic lesions in the brain to suggest lymphoma. Hypometabolism is seen in the right frontal operculum and left frontal vertex. There is a larger area of subtle asymmetric decreased FDG activity seen in posterior left frontal lobe and left parietal lobe.", "width": 914, "height": 506, "subcaptions": null, "subfigures": [{"id": "4aeeb2a2-f68f-41f5-afd8-54f21d98584a", "label": "a", "points": [[42.3, 1.3], [42.3, 473.4], [453.8, 473.4], [453.8, 1.3]], "color": "yellow"}, {"id": "fd033730-575d-4a9a-be86-aff51f122b49", "label": "b", "points": [[479.8, 5.6], [479.8, 474.8], [882.6, 474.8], [882.6, 5.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "PET", "start": 10, "end": 13, "id": 3}, {"text": "scan", "start": 14, "end": 18, "id": 4}, {"text": "of", "start": 19, "end": 21, "id": 5}, {"text": "the", "start": 22, "end": 25, "id": 6}, {"text": "brain", "start": 26, "end": 31, "id": 7}, {"text": "showing", "start": 32, "end": 39, "id": 8}, {"text": "no", "start": 40, "end": 42, "id": 9}, {"text": "hypermetabolic", "start": 43, "end": 57, "id": 10}, {"text": "lesions", "start": 58, "end": 65, "id": 11}, {"text": "in", "start": 66, "end": 68, "id": 12}, {"text": "the", "start": 69, "end": 72, "id": 13}, {"text": "brain", "start": 73, "end": 78, "id": 14}, {"text": "to", "start": 79, "end": 81, "id": 15}, {"text": "suggest", "start": 82, "end": 89, "id": 16}, {"text": "lymphoma", "start": 90, "end": 98, "id": 17}, {"text": ".", "start": 98, "end": 99, "id": 18}, {"text": "Hypometabolism", "start": 100, "end": 114, "id": 19}, {"text": "is", "start": 115, "end": 117, "id": 20}, {"text": "seen", "start": 118, "end": 122, "id": 21}, {"text": "in", "start": 123, "end": 125, "id": 22}, {"text": "the", "start": 126, "end": 129, "id": 23}, {"text": "right", "start": 130, "end": 135, "id": 24}, {"text": "frontal", "start": 136, "end": 143, "id": 25}, {"text": "operculum", "start": 144, "end": 153, "id": 26}, {"text": "and", "start": 154, "end": 157, "id": 27}, {"text": "left", "start": 158, "end": 162, "id": 28}, {"text": "frontal", "start": 163, "end": 170, "id": 29}, {"text": "vertex", "start": 171, "end": 177, "id": 30}, {"text": ".", "start": 177, "end": 178, "id": 31}, {"text": "There", "start": 179, "end": 184, "id": 32}, {"text": "is", "start": 185, "end": 187, "id": 33}, {"text": "a", "start": 188, "end": 189, "id": 34}, {"text": "larger", "start": 190, "end": 196, "id": 35}, {"text": "area", "start": 197, "end": 201, "id": 36}, {"text": "of", "start": 202, "end": 204, "id": 37}, {"text": "subtle", "start": 205, "end": 211, "id": 38}, {"text": "asymmetric", "start": 212, "end": 222, "id": 39}, {"text": "decreased", "start": 223, "end": 232, "id": 40}, {"text": "FDG", "start": 233, "end": 236, "id": 41}, {"text": "activity", "start": 237, "end": 245, "id": 42}, {"text": "seen", "start": 246, "end": 250, "id": 43}, {"text": "in", "start": 251, "end": 253, "id": 44}, {"text": "posterior", "start": 254, "end": 263, "id": 45}, {"text": "left", "start": 264, "end": 268, "id": 46}, {"text": "frontal", "start": 269, "end": 276, "id": 47}, {"text": "lobe", "start": 277, "end": 281, "id": 48}, {"text": "and", "start": 282, "end": 285, "id": 49}, {"text": "left", "start": 286, "end": 290, "id": 50}, {"text": "parietal", "start": 291, "end": 299, "id": 51}, {"text": "lobe", "start": 300, "end": 304, "id": 52}, {"text": ".", "start": 304, "end": 305, "id": 53}]}
{"pdf_hash": "df5936defae201ec643c48285b625f571f473fe5", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "FIG. 4. Immunolocalization of RGS9 in bovine retina by monoclonal antibody. (A) RGS9 immunoblot showing labeling of RGS9 from bovine ROS and full-length and truncated forms of bacterially expressed RGS9. ROS, bovine ROS (20 mg rhodopsin). Lane 1, His-RGS9 (delta30N, 0.6 mg) corresponding to aa 31\u2013484. Lane 2, His-RGS9c (0.6 mg) corresponding to aa 226\u2013484. Lane 3, His-RGS9d (0.6 mg) corresponding to aa 291\u2013418. (B\u2013D) Confocal immunolocalization. RGS9 immunolabeling (B and C) is present in rod and cone photoreceptors. These sensory neurons extend from the outer segment layer (OS) to the outer plexiform layer (OPL) where their axons terminate. Antibody labeling is more prominent in the cones, whose cell soma are adjacent to the IS layer, in the outer most tier of the outer nuclear layer (ONL). Antibody labeling was not observed in the inner nuclear layer (INL), inner plexiform layer (IPL), or ganglion cell layer (GCL). At higher magnification (C), the subcellular distribution of RGS9 in rods and cones is demonstrated. Cone OS are heavily labeled (arrowheads), whereas rod OS (}) are less intensely labeled. Rod and cone IS are also RGS9 immunopositive, although labeling is more pronounced in the cones. Cone photoreceptors terminate in the OPL where their axons form synaptic terminals. Cone axons and synaptic terminals (arrow) are positive for RGS9. (D) RGS9 immunolabeling is abolished by preadsorbing the antibody with purified RGS9 protein coupled to CNBr-activated Sepharose. Scale bars are 50 mm in B and D and 20 mm in C.", "width": 1348, "height": 512, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94], "b": [95, 96, 100, 101, 102, 103, 104, 105, 106, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204], "c": [95, 96, 97, 98, 99, 100, 101, 102, 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{"pdf_hash": "6a7b3f095f00cd7daa3efd1bd655146caf56c506", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Microscopy of the pitviper infrared receptor organ. (A\u2013D) Scanning electron micrographs of the papillae of Bothropoides jararaca. (A) General view and (B) higher magnification of the base of the papillae, focusing on the transition from the flat epithelium (*) to the domed epithelium (de) that lines the duct and bottom of the inner chamber. (C, D) High magnification of the surface of the (C) papilla and (D) pit membrane. Note the cell limits (CL) and micropits (arrows). (E, F) Light micrographs of Bothrops asper. (E) Longitudinal section of one papilla (pa) and part of the inner chamber showing epithelial domes (arrows). (F) Transverse section of two papillae. 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{"pdf_hash": "934aaa9e9ed37b40bb0fff3291c6e5a50676d6de", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Figure 5 Representative computed tomography findings in case no. 15 after direct-acting antiviral (DAA) HCC recurrence: (a) 2.5 years before DAA treatment; (b) after RFA therapy; (c) at the time of sofosbuvir + ribavirin (SOF + RBV) treatment; and (d) 8 and (f ) 19 months after DAA treatment. Red arrows, hepatocellular carcinoma (HCC). (e) Abdominal angiography 8 months after DAA treatment. HCC was observed 2.5 years before DAA treatment (a) and was completely cured by radiofrequency ablation (RFA) therapy (b). SOF + RBV was administered for 3 months (c). Tiny HCCs were observed 8 months after DAA treatment (d), and hepatic arteriography showed multiple tumors with des-gamma-carboxy pro-thrombin (DCP) elevation (e). HCC was uncontrollable despite many treatments (f ). 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{"pdf_hash": "33da20f1773bf650d3466a41a65805e45b9b4a10", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. TIRF imaging of actin networks and their reorganization in the cortex of Dictyostelium cells. (A) Illumination at a high incidence angle (blue) generates an evanescent field that illuminates the cortical actin network of 100 -200-nm thickness (green). Molecules diffusing in the cytoplasm are illuminated only for the fraction of time they persist within the evanescent field, a period that is prolonged by incorporation into the cytoskeleton (red double arrows). (B) TIRF image of the actin network visualized by LimE\u232ccoil-GFP in a cell immobilized by tight compression under an agar sheet, taken at an exposure time of 100 msec. (C) Two-dimensional color space where I t indicates color coding of the gray scale for the first frame (green) and I t \u03e9 1 indicates color coding of the gray scale for the second frame (red). Mixed colors (yellow tones) represent structures that persist from the first frame to the second frame with constant or slightly varying fluorescence intensity. (D) Superposition of two TIRF images of the cell shown in B, recorded at a 500-msec interval and color-coded as in C. Areas of very densely packed actin filaments with fluorescence intensities beyond the linear range of the 0 -255 gray scale are left uncolored. (E-G) gain fi in a TIRF image series recorded at 100-msec intervals. (E) Snapshot at the beginning of the series. (F) gain fi during a period of 200 msec obtained by image subtraction, colored in red. (G) gain fi obtained by subtracting 20 consecutive frames from each other, presented as a maximum projection over the period of 2 sec. The gray and color bars indicate contrast enhancement. 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{"pdf_hash": "3557783b97215319265f3758f8b304a2da103640", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "FIGURE 6. Fundus imaging of CTRL (A) and LIRD (B) Long Evans rats that received intravitreal injection of H-800CW in the superior limbus. A representative IR fundus image (C) coplanar to ICG fluorescent images (A, B) is included to show that fluorescence was located deep within the retina, but anterior to the choroidal vessels.", "width": 962, "height": 342, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [3, 4, 5, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "c": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "35770914-f8f4-4e25-93ac-26deea101715", "label": "a", "points": [[6.9, 1.3], [6.9, 311.3], [313.9, 311.3], [313.9, 1.3]], "color": "yellow"}, {"id": "de4f5c6d-58b7-4f03-897d-dd2165386c17", "label": "b", "points": [[324.5, 1.3], [324.5, 308.2], [628.4, 308.2], [628.4, 1.3]], "color": "cyan"}, {"id": "a0ad64dd-7a06-4192-aa9e-beaee3dc5f0f", "label": "c", "points": [[645.2, -0.2], [645.2, 309.8], [946.1, 309.8], [946.1, -0.2]], "color": "magenta"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Fundus", "start": 10, "end": 16, "id": 3}, {"text": "imaging", "start": 17, "end": 24, "id": 4}, {"text": "of", "start": 25, "end": 27, "id": 5}, {"text": "CTRL", "start": 28, "end": 32, "id": 6}, {"text": "(", "start": 33, "end": 34, "id": 7}, {"text": "A", "start": 34, "end": 35, "id": 8}, {"text": ")", "start": 35, "end": 36, "id": 9}, {"text": "and", "start": 37, "end": 40, "id": 10}, {"text": "LIRD", "start": 41, "end": 45, "id": 11}, {"text": "(", "start": 46, "end": 47, "id": 12}, {"text": "B", "start": 47, "end": 48, "id": 13}, {"text": ")", "start": 48, "end": 49, "id": 14}, {"text": "Long", "start": 50, "end": 54, "id": 15}, {"text": "Evans", "start": 55, "end": 60, "id": 16}, {"text": "rats", "start": 61, "end": 65, "id": 17}, {"text": "that", "start": 66, "end": 70, "id": 18}, {"text": "received", "start": 71, "end": 79, "id": 19}, {"text": "intravitreal", "start": 80, "end": 92, "id": 20}, {"text": "injection", "start": 93, "end": 102, "id": 21}, {"text": "of", "start": 103, "end": 105, "id": 22}, {"text": "H-800CW", "start": 106, "end": 113, "id": 23}, {"text": "in", "start": 114, "end": 116, "id": 24}, {"text": "the", "start": 117, "end": 120, "id": 25}, {"text": "superior", "start": 121, "end": 129, "id": 26}, {"text": "limbus", "start": 130, "end": 136, "id": 27}, {"text": ".", "start": 136, "end": 137, "id": 28}, {"text": "A", "start": 138, "end": 139, "id": 29}, {"text": "representative", "start": 140, "end": 154, "id": 30}, {"text": "IR", "start": 155, "end": 157, "id": 31}, {"text": "fundus", "start": 158, "end": 164, "id": 32}, {"text": "image", "start": 165, "end": 170, "id": 33}, {"text": "(", "start": 171, "end": 172, "id": 34}, {"text": "C", "start": 172, "end": 173, "id": 35}, {"text": ")", "start": 173, "end": 174, "id": 36}, {"text": "coplanar", "start": 175, "end": 183, "id": 37}, {"text": "to", "start": 184, "end": 186, "id": 38}, {"text": "ICG", "start": 187, "end": 190, "id": 39}, {"text": "fluorescent", "start": 191, "end": 202, "id": 40}, {"text": "images", "start": 203, "end": 209, "id": 41}, {"text": "(", "start": 210, "end": 211, "id": 42}, {"text": "A", "start": 211, "end": 212, "id": 43}, {"text": ",", "start": 212, "end": 213, "id": 44}, {"text": "B", "start": 214, "end": 215, "id": 45}, {"text": ")", "start": 215, "end": 216, "id": 46}, {"text": "is", "start": 217, "end": 219, "id": 47}, {"text": "included", "start": 220, "end": 228, "id": 48}, {"text": "to", "start": 229, "end": 231, "id": 49}, {"text": "show", "start": 232, "end": 236, "id": 50}, {"text": "that", "start": 237, "end": 241, "id": 51}, {"text": "fluorescence", "start": 242, "end": 254, "id": 52}, {"text": "was", "start": 255, "end": 258, "id": 53}, {"text": "located", "start": 259, "end": 266, "id": 54}, {"text": "deep", "start": 267, "end": 271, "id": 55}, {"text": "within", "start": 272, "end": 278, "id": 56}, {"text": "the", "start": 279, "end": 282, "id": 57}, {"text": "retina", "start": 283, "end": 289, "id": 58}, {"text": ",", "start": 289, "end": 290, "id": 59}, {"text": "but", "start": 291, "end": 294, "id": 60}, {"text": "anterior", "start": 295, "end": 303, "id": 61}, {"text": "to", "start": 304, "end": 306, "id": 62}, {"text": "the", "start": 307, "end": 310, "id": 63}, {"text": "choroidal", "start": 311, "end": 320, "id": 64}, {"text": "vessels", "start": 321, "end": 328, "id": 65}, {"text": ".", "start": 328, "end": 329, "id": 66}]}
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{"pdf_hash": "97261009c6753db3d23d2274d262cc452296016f", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "FIGURE 3: Most P-body components are not nucleocytoplasmic proteins. (A) Fluorescence imaging of HeLa cells treated with LMB for 5 h (+LMB) or with methanol as a control (\u2212LMB) stained with antibodies against P-body components as indicated, including 4E-T, Dcp1a, rck/p54, Edc3, Ge-1, and Xrn1. Scale bar, 10 \u03bcm. (B) Graph of % of cells containing indicated numbers of P-bodies in the presence (+) or absence (\u2212) of LMB, as seen with \u03b1-rck/p54.", "width": 476, "height": 1596, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 68], "b": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 56, 68], "c": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 59, 60, 68], "d": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 62, 68], "e": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 64, 68], "f": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 67, 68], "g": [13, 14, 15, 16, 17, 18, 19, 20, 21, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 68], "h": [13, 14, 15, 16, 17, 18, 19, 20, 21, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 56, 68], "i": [13, 14, 15, 16, 17, 18, 19, 20, 21, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 58, 59, 60, 68], "j": [13, 14, 15, 16, 17, 18, 19, 20, 21, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 62, 68], "k": [13, 14, 15, 16, 17, 18, 19, 20, 21, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 64, 68], "l": [13, 14, 15, 16, 17, 18, 19, 20, 21, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 67, 68], "m": [75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112]}, 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{"pdf_hash": "92fd67dc4363ba76776f2cc046a7809adf4ea8b6", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. Defects in the cardiac outflow tract of GATA4 \u03e9/\u03ea \u035e6 \u03e9/\u03ea embryos. (A and B) India ink was injected into the left ventricle of beating hearts of WT (A) and GATA4 \u03e9/\u03ea \u035e6 \u03e9/\u03ea (B) embryos at E12.5. The atria were removed, and the right lateral views of the heart and great vessels are shown. (C and D) Transverse sections of WT and GATA4 \u03e9/\u03ea \u035e6 \u03e9/\u03ea mutants at E12.5 displaying incomplete septation between the outflow tract and the pulmonary trunk. aao, ascending aorta, dao, descending aorta; pt, pulmonary trunk; pta, persistent truncus arteriosis; rv, right ventricle.", "width": 522, "height": 424, "subcaptions": {"a": [17, 18, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68], "b": [17, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68], "c": [69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97]}, "subfigures": [{"id": "b9457e58-4c81-4a4f-8b63-1923ac4244b4", "label": "a", "points": [[25, 30.8], [25, 203.8], [258, 203.8], [258, 30.8]], "color": "yellow"}, 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{"pdf_hash": "40ec5fb42b3b100774503eaa813b40705aa44feb", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Both DWIBS (a and b) and contrast CT (c) showing artery inflammation of the left subclavian artery. DWIBS: diffusion-weighted whole-body imaging with background body signal suppression", "width": 962, "height": 716, "subcaptions": {"a": [4, 5, 6, 7, 8, 9], "b": [11, 12, 13, 14, 15]}, "subfigures": [{"id": "92bf9542-eb86-4219-9a8b-dcbffba1cb0a", "label": "a", "points": [[1.5, 6.1], [1.5, 686.9], [387.5, 686.9], [387.5, 6.1]], "color": "yellow"}, {"id": "8717633a-3b5f-4d89-9e5d-8c61dc053615", "label": "a", "points": [[396.7, 1.5], [396.7, 326.7], [940.7, 326.7], [940.7, 1.5]], "color": "cyan"}, {"id": "d451b009-39e9-4651-82a7-4226eef7e921", "label": "b", "points": [[399.7, 337.4], [399.7, 685.4], [936.2, 685.4], [936.2, 337.4]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Both", "start": 10, "end": 14, "id": 3}, {"text": "DWIBS", "start": 15, "end": 20, "id": 4}, {"text": "(", "start": 21, "end": 22, "id": 5}, {"text": "a", "start": 22, "end": 23, "id": 6}, {"text": "and", "start": 24, "end": 27, "id": 7}, {"text": "b", "start": 28, "end": 29, "id": 8}, {"text": ")", "start": 29, "end": 30, "id": 9}, {"text": "and", "start": 31, "end": 34, "id": 10}, {"text": "contrast", "start": 35, "end": 43, "id": 11}, {"text": "CT", "start": 44, "end": 46, "id": 12}, {"text": "(", "start": 47, "end": 48, "id": 13}, {"text": "c", "start": 48, "end": 49, "id": 14}, {"text": ")", "start": 49, "end": 50, "id": 15}, {"text": "showing", "start": 51, "end": 58, "id": 16}, {"text": "artery", "start": 59, "end": 65, "id": 17}, {"text": "inflammation", "start": 66, "end": 78, "id": 18}, {"text": "of", "start": 79, "end": 81, "id": 19}, {"text": "the", "start": 82, "end": 85, "id": 20}, {"text": "left", "start": 86, "end": 90, "id": 21}, {"text": "subclavian", "start": 91, "end": 101, "id": 22}, {"text": "artery", "start": 102, "end": 108, "id": 23}, {"text": ".", "start": 108, "end": 109, "id": 24}, {"text": "DWIBS", "start": 110, "end": 115, "id": 25}, {"text": ":", "start": 115, "end": 116, "id": 26}, {"text": "diffusion", "start": 117, "end": 126, "id": 27}, {"text": "-", "start": 126, "end": 127, "id": 28}, {"text": "weighted", "start": 127, "end": 135, "id": 29}, {"text": "whole", "start": 136, "end": 141, "id": 30}, {"text": "-", "start": 141, "end": 142, "id": 31}, {"text": "body", "start": 142, "end": 146, "id": 32}, {"text": "imaging", "start": 147, "end": 154, "id": 33}, {"text": "with", "start": 155, "end": 159, "id": 34}, {"text": "background", "start": 160, "end": 170, "id": 35}, {"text": "body", "start": 171, "end": 175, "id": 36}, {"text": "signal", "start": 176, "end": 182, "id": 37}, {"text": "suppression", "start": 183, "end": 194, "id": 38}]}
{"pdf_hash": "e55464181d1e38990d4056b43b695ac17ca6b517", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Optical coherence tomography (OCT) angiography images of a patient with supero-temporal branch retinal vein occlusion: deep retinal plexus before dexamethasone implant (panel A) showing areas of telangiectatic vessels (red squares) and after dexamethasone implant (panel B), showing vessel caliber reduction (green squares).", "width": 900, "height": 636, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [56, 58, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 23, 24, 25, 55, 59, 57]}, "subfigures": [{"id": "04fd1c56-0037-4b8b-abf1-47431c0bee31", "label": "a", "points": [[5.7, 2.8], [5.7, 634.1], [420.9, 634.1], [420.9, 2.8]], "color": "yellow"}, {"id": "8d4cf022-168f-4131-8bef-c3a9354c8703", "label": "b", "points": [[482, 2.8], [482, 628.4], [894.3, 628.4], [894.3, 2.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Optical", "start": 10, "end": 17, "id": 3}, {"text": "coherence", "start": 18, "end": 27, "id": 4}, {"text": "tomography", "start": 28, "end": 38, "id": 5}, {"text": "(", "start": 39, "end": 40, "id": 6}, {"text": "OCT", "start": 40, "end": 43, "id": 7}, {"text": ")", "start": 43, "end": 44, "id": 8}, {"text": "angiography", "start": 45, "end": 56, "id": 9}, {"text": "images", "start": 57, "end": 63, "id": 10}, {"text": "of", "start": 64, "end": 66, "id": 11}, {"text": "a", "start": 67, "end": 68, "id": 12}, {"text": "patient", "start": 69, "end": 76, "id": 13}, {"text": "with", "start": 77, "end": 81, "id": 14}, {"text": "supero", "start": 82, "end": 88, "id": 15}, {"text": "-", "start": 88, "end": 89, "id": 16}, {"text": "temporal", "start": 89, "end": 97, "id": 17}, {"text": "branch", "start": 98, "end": 104, "id": 18}, {"text": "retinal", "start": 105, "end": 112, "id": 19}, {"text": "vein", "start": 113, "end": 117, "id": 20}, {"text": "occlusion", "start": 118, "end": 127, "id": 21}, {"text": ":", "start": 127, "end": 128, "id": 22}, {"text": "deep", "start": 129, "end": 133, "id": 23}, {"text": "retinal", "start": 134, "end": 141, "id": 24}, {"text": "plexus", "start": 142, "end": 148, "id": 25}, {"text": "before", "start": 149, "end": 155, "id": 26}, {"text": "dexamethasone", "start": 156, "end": 169, "id": 27}, {"text": "implant", "start": 170, "end": 177, "id": 28}, {"text": "(", "start": 178, "end": 179, "id": 29}, {"text": "panel", "start": 179, "end": 184, "id": 30}, {"text": "A", "start": 185, "end": 186, "id": 31}, {"text": ")", "start": 186, "end": 187, "id": 32}, {"text": "showing", "start": 188, "end": 195, "id": 33}, {"text": "areas", "start": 196, "end": 201, "id": 34}, {"text": "of", "start": 202, "end": 204, "id": 35}, {"text": "telangiectatic", "start": 205, "end": 219, "id": 36}, {"text": "vessels", "start": 220, "end": 227, "id": 37}, {"text": "(", "start": 228, "end": 229, "id": 38}, {"text": "red", "start": 229, "end": 232, "id": 39}, {"text": "squares", "start": 233, "end": 240, "id": 40}, {"text": ")", "start": 240, "end": 241, "id": 41}, {"text": "and", "start": 242, "end": 245, "id": 42}, {"text": "after", "start": 246, "end": 251, "id": 43}, {"text": "dexamethasone", "start": 252, "end": 265, "id": 44}, {"text": "implant", "start": 266, "end": 273, "id": 45}, {"text": "(", "start": 274, "end": 275, "id": 46}, {"text": "panel", "start": 275, "end": 280, "id": 47}, {"text": "B", "start": 281, "end": 282, "id": 48}, {"text": ")", "start": 282, "end": 283, "id": 49}, {"text": ",", "start": 283, "end": 284, "id": 50}, {"text": "showing", "start": 285, "end": 292, "id": 51}, {"text": "vessel", "start": 293, "end": 299, "id": 52}, {"text": "caliber", "start": 300, "end": 307, "id": 53}, {"text": "reduction", "start": 308, "end": 317, "id": 54}, {"text": "(", "start": 318, "end": 319, "id": 55}, {"text": "green", "start": 319, "end": 324, "id": 56}, {"text": "squares", "start": 325, "end": 332, "id": 57}, {"text": ")", "start": 332, "end": 333, "id": 58}, {"text": ".", "start": 333, "end": 334, "id": 59}]}
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{"pdf_hash": "d9562841cce9afc105fb75043ae3d15db68cbfc1", "fig_key": "Figure8", "fig_uri": "5-Figure8-1.png", "text": "Fig. 8 In a 69-year-old woman with advanced carcinoma of the gastric body, palliative total gastrectomy was performed. Five days after surgery, CF (A) showed patent EJS with opacification of extensive anastomotic leakage (*). A few days later, on conservative management, contrastenhanced CT (B-D) showed bilateral pleural effusions and atelectasis (B), patent EJS (arrowheads) and persistent leak (*)", "width": 660, "height": 688, "subcaptions": {"a": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "8885fb54-b365-4412-909a-3e91197fdda1", "label": "a", "points": [[2.1, 4.2], [2.1, 327.4], [330.5, 327.4], [330.5, 4.2]], "color": "yellow"}, {"id": "424f1374-9bc2-49b2-99f7-9591cec0b204", "label": "b", "points": [[334.7, 326.4], [334.7, 5.2], [659, 5.2], [659, 326.4]], "color": "cyan"}, {"id": "4ca68ecb-97f4-46db-898a-72b23cbd776d", "label": "c", "points": [[328.4, 662.1], [328.4, 333.7], [1, 333.7], [1, 662.1]], "color": "magenta"}, {"id": "116080a7-bd20-46a6-9e4f-842eca11aec7", "label": "d", "points": [[334.7, 334.7], [334.7, 659], [659, 659], [659, 334.7]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, 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{"pdf_hash": "ba5745e0c96dbf2a15d29bdd9b29287cfa62c4b4", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Figure 6. Axial (a) and coronal (b) contrast enhanced MDCT images in the arterial phase demonstrate a nodular mass of the jejunum (white circles). This GIST presents heterogeneous contrast enhancement, irregular margins and size < 5 cm. Just above, there is a diffuse reticular thickening of mesenteric adipose tissue (a, white arrow), suggestive for multiple serosal-based nodules. Furthermore coronal (b) contrast-enhanced MDCT image shows a hypovascular liver metastasis (white arrow)", "width": 1314, "height": 516, "subcaptions": {"a": [3, 4, 5, 6, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93]}, "subfigures": [{"id": "b8c858c8-3c77-4d4f-be8f-8c58a0e13603", "label": "a", "points": [[0, 22.8], [0, 514.8], [699.6, 514.8], [699.6, 22.8]], "color": "yellow"}, {"id": "9a51839d-d843-4f9f-ab90-7b42bb6838f4", "label": "b", "points": [[1312, 24.9], [1312, 514.8], [703.7, 514.8], [703.7, 24.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, 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{"pdf_hash": "243df298645b1983c240c1ee23332a602e641e92", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Preoperative whole-body positron emission tomography findings suggest lung cancer in the right lower lobe, and bone metastases in the T3 and L3 vertebral bodies.", "width": 630, "height": 540, "subcaptions": null, "subfigures": [{"id": "1d788300-4b7d-4878-b91c-f7cd23dc820c", "label": "a", "points": [[1, 39], [1, 510], [310, 510], [310, 39]], "color": "yellow"}, {"id": "5d7d46f1-9cae-48f7-b983-aac8ec60edb4", "label": "b", "points": [[317, 40], [317, 508], [626, 508], [626, 40]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Preoperative", "start": 8, "end": 20, "id": 4}, {"text": "whole", "start": 21, "end": 26, "id": 5}, {"text": "-", "start": 26, "end": 27, "id": 6}, {"text": "body", "start": 27, "end": 31, "id": 7}, {"text": "positron", "start": 32, "end": 40, "id": 8}, {"text": "emission", "start": 41, "end": 49, "id": 9}, {"text": "tomography", "start": 50, "end": 60, "id": 10}, {"text": "findings", "start": 61, "end": 69, "id": 11}, {"text": "suggest", "start": 70, "end": 77, "id": 12}, {"text": "lung", "start": 78, "end": 82, "id": 13}, {"text": "cancer", "start": 83, "end": 89, "id": 14}, {"text": "in", "start": 90, "end": 92, "id": 15}, {"text": "the", "start": 93, "end": 96, "id": 16}, {"text": "right", "start": 97, "end": 102, "id": 17}, {"text": "lower", "start": 103, "end": 108, "id": 18}, {"text": "lobe", "start": 109, "end": 113, "id": 19}, {"text": ",", "start": 113, "end": 114, "id": 20}, {"text": "and", "start": 115, "end": 118, "id": 21}, {"text": "bone", "start": 119, "end": 123, "id": 22}, {"text": "metastases", "start": 124, "end": 134, "id": 23}, {"text": "in", "start": 135, "end": 137, "id": 24}, {"text": "the", "start": 138, "end": 141, "id": 25}, {"text": "T3", "start": 142, "end": 144, "id": 26}, {"text": "and", "start": 145, "end": 148, "id": 27}, {"text": "L3", "start": 149, "end": 151, "id": 28}, {"text": "vertebral", "start": 152, "end": 161, "id": 29}, {"text": "bodies", "start": 162, "end": 168, "id": 30}, {"text": ".", "start": 168, "end": 169, "id": 31}]}
{"pdf_hash": "680d06fb052e3d84acafbc608d737f3cb214d3fe", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Thin capped fibroatheroma (TCFA) with rupture and without rupture in a patient with acute myocardial infarction. A1, B1, C1 -Culprit lesion in right coronary artery (RCA). (A1) Coronary angiogram shows a severe stenosis with haziness in the middle of the RCA. Optical coherence tomography (B1, C1) reveals ruptured plaque; the thinnest part measures 50 \u00b5m. Serum CRP and IL-6 in this patient were 1.23 mg/l and 12.3 pg/dl respectively. A2, B2, C2 -Culprit lesion in RCA in a patient with unstable angina pectoris. (A2) Angiographic finding in culprit lesion in a patient with unstable angina pectoris. Severe stenosis in distal RCA was observed. Optical coherence tomography (B2, C2) in culprit lesion shows a large lipid-rich (* * ) plaque covered by a thin fibrous cap (thinnest part 60 \u00b5m). Minimum lumen area is 1.6 mm 2 . 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{"pdf_hash": "44957965cca7bc5e0f4ddff9e59fbed183049e17", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Dog 5 of PH group. (A) Dorsal contrast-enhanced multiplanar reformatted CT image of the abdomen. There are multiple hepatic neoformations (asterisks) ipoattenuating to hepatic parenchyma, periportal lymph nodes enlargement (lf) and no abdominal effusion. (B,C,D,E) Three-dimensional volume rendered image of the portal vein (p) and caudal vena cava (CVC) \u2013 ventral views. Two large vessels (empty and full arrowheads) originate respectively from the pancreaticoduodenal vein (pd) and from splenic vein (sv), run caudally and join in a single vessel draining into the caudal vena cava at level of right gonadal vein (rg). (B) whole portal vein, ventral view; (C) detail of the entire PSS from its double portal origin to its caval termination; (D) detail of origins of the anomalous vessels from pancreaticoduodenal vein (empty arrowhead) and splenic vein (full arrowhead); (E) detail of connection (arrow) of the two shunts in one vessel which enters caudal vena cava at level of right gonadal vein. These vessels appeared suggestive of APSS because they were associated with a visible cause of PH (diffuse hepatic neoplasia) and other classical APSS (see Fig. 5). The absence of ascites could be explained by a complete effectiveness of these APSS in alleviating portal pressure. 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{"pdf_hash": "8eb706c1457bd3259fc90a1cfb9eda50b90ff806", "fig_key": "Figure5", "fig_uri": "9-Figure5-1.png", "text": "Fig. 5. Other regional trends in class II MHC expression. The drawing at upper right shows the location of the hippocampal injection site of IFN-\u2425 (arrow) in a coronal section and the approximate locations of the photographed areas shown in the other panels. Class II \u03e9 microglia in cortex (Cx), corpus callosum (Cc), and caudate (C) are shown. (Class II \u03e9 cells appear dark brown after staining with monoclonal antibody OX6). Note the striking differences in the numbers of class II \u03e9 microglia in the different areas, despite their proximity to each other and similar distances from the injection site. Scale bar \u03ed 20 m. Figure 5 is reprinted with permission from John Wiley & Sons. Site-specific immune regulation in the brain: Differential modulation of MHC proteins in brainstem and hippocampus. LM Phillips, PJ Simon, and LA Lampson, J. Comp. 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{"pdf_hash": "c1889bec21244a803031fc10ea4971ae75b5d2e3", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Magnetic resonance images (MRI) in patients with posterior reversible encephalopathy during treatment with the HLH-2004 protocol. MRI showed decreased signal on T1-weighted images and hyperintense abnormalities on T2-weighted and fluid attenuated inversion recovery (FLAIR) images (A\u2012F) typical for PRES, bilaterally in the subcortical white matter and cortical gray matter of the posterior parietal and occipital lobes. These initial increased signal lesions completely disappeared after 1 to 2 months of treatment (D2 and E2).", "width": 1374, "height": 762, "subcaptions": {"a": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88]}, "subfigures": [{"id": "5ffde46a-db27-4036-b518-71725a71c05b", "label": "a", "points": [[35.1, 27.5], [35.1, 370.5], [347.7, 370.5], [347.7, 27.5]], "color": "yellow"}, {"id": "16eb3ce2-fd06-4563-959f-07e446aa5afe", "label": "a", "points": [[356.4, 29.7], [356.4, 372.6], [671.1, 372.6], [671.1, 29.7]], "color": "cyan"}, {"id": "a90f320b-8c39-4b52-9f7b-d87c81786b66", "label": "a", 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{"pdf_hash": "a92654127fea8b3d23b54ce3c1018dd021518383", "fig_key": "Figure4", "fig_uri": "1-Figure4-1.png", "text": "Figure 4 CT scan of the abdomen with coronal view showing intussusception of the small bowel.", "width": 1192, "height": 608, "subcaptions": null, "subfigures": [{"id": "2eb4bc72-8688-478b-a02e-ad606c0ecb14", "label": "a", "points": [[107.7, 85.4], [107.7, 590.1], [604.8, 590.1], [604.8, 85.4]], "color": "yellow"}, {"id": "beab427e-e186-484e-b6b9-9d81789ee256", "label": "b", "points": [[685.8, 0.6], [685.8, 597.6], [1190.5, 597.6], [1190.5, 0.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "CT", "start": 9, "end": 11, "id": 2}, {"text": "scan", "start": 12, "end": 16, "id": 3}, {"text": "of", "start": 17, "end": 19, "id": 4}, {"text": "the", "start": 20, "end": 23, "id": 5}, {"text": "abdomen", "start": 24, "end": 31, "id": 6}, {"text": "with", "start": 32, "end": 36, "id": 7}, {"text": "coronal", "start": 37, "end": 44, "id": 8}, {"text": "view", "start": 45, "end": 49, "id": 9}, {"text": "showing", "start": 50, "end": 57, "id": 10}, {"text": "intussusception", "start": 58, "end": 73, "id": 11}, {"text": "of", "start": 74, "end": 76, "id": 12}, {"text": "the", "start": 77, "end": 80, "id": 13}, {"text": "small", "start": 81, "end": 86, "id": 14}, {"text": "bowel", "start": 87, "end": 92, "id": 15}, {"text": ".", "start": 92, "end": 93, "id": 16}]}
{"pdf_hash": "be8acc5260daf988afe1d4eb69b6fcdda6bf1eaf", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Patient clinical information. (a) Ictal electroencephalogram (EEG) examined at 6 months. A short EEG seizure discharge begins at the right frontal region. (b\u2013d) Brain magnetic resonance imaging examined at 6 months. Extracerebral spaces can be seen in axial images, (b and c) possibly indicating brain atrophy. Both (b) T1- and (c) T2-weighted images show high intensity in the deep white matter, indicating delayed myelination. 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{"pdf_hash": "42e0c938e09048d2e448cf3594c34d405813d92f", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. (a) Electron microscope picture depicting two mature endoconidia. The reddish vesicles observed in Fig. 1(a, b) appear in this EM figure as dark electron-dense bodies (EDB) devoid of internal structures. The endoconidium in the right section shows a distinctive R. seeberi nucleus with a typical nucleolus both surrounded by a nuclear membrane (arrow). Bar, 2.5 mm. (b) Electron micrograph of three JS, two of them displaying nuclei with prominent nucleoli (arrows) identical to the one observed in the endoconidium of (a). Figure reproduced from Silva et al. (2005) and Vilela & Mendoza (2012). Bar, 16.0 mm. (c) An IS with numerous nuclei at the same partitioning stage (arrows), some of them containing nucleoli. Figure reproduced from Herr et al. (1999a). 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{"pdf_hash": "465ee71437746de669e2c55e40c4deeaa576dcff", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Preoperative computed tomography (ct) scan (a: axial reconstruction; b: coronal reconstruction) showing a mass with a poor vascularization and a collapsed area in the lower pole of the left kidney.", "width": 688, "height": 896, "subcaptions": {"a": [11, 12, 13, 14], "b": [16, 17, 18, 19]}, "subfigures": [{"id": "589f4ddd-f431-42e9-9e15-a04f0cf46f97", "label": "a", "points": [[34.8, 30.4], [34.8, 461.9], [683.7, 461.9], [683.7, 30.4]], "color": "yellow"}, {"id": "e0348eb4-918d-4ab6-bcdf-610676e0d728", "label": "b", "points": [[33.7, 894.5], [33.7, 465.2], [684.7, 465.2], [684.7, 894.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Preoperative", "start": 10, "end": 22, "id": 3}, {"text": "computed", "start": 23, "end": 31, "id": 4}, {"text": "tomography", "start": 32, "end": 42, "id": 5}, {"text": "(", "start": 43, "end": 44, "id": 6}, {"text": "ct", "start": 44, "end": 46, "id": 7}, {"text": ")", "start": 46, "end": 47, "id": 8}, {"text": "scan", "start": 48, "end": 52, "id": 9}, {"text": "(", "start": 53, "end": 54, "id": 10}, {"text": "a", "start": 54, "end": 55, "id": 11}, {"text": ":", "start": 55, "end": 56, "id": 12}, {"text": "axial", "start": 57, "end": 62, "id": 13}, {"text": "reconstruction", "start": 63, "end": 77, "id": 14}, {"text": ";", "start": 77, "end": 78, "id": 15}, {"text": "b", "start": 79, "end": 80, "id": 16}, {"text": ":", "start": 80, "end": 81, "id": 17}, {"text": "coronal", "start": 82, "end": 89, "id": 18}, {"text": "reconstruction", "start": 90, "end": 104, "id": 19}, {"text": ")", "start": 104, "end": 105, "id": 20}, {"text": "showing", "start": 106, "end": 113, "id": 21}, {"text": "a", "start": 114, "end": 115, "id": 22}, {"text": "mass", "start": 116, "end": 120, "id": 23}, {"text": "with", "start": 121, "end": 125, "id": 24}, {"text": "a", "start": 126, "end": 127, "id": 25}, {"text": "poor", "start": 128, "end": 132, "id": 26}, {"text": "vascularization", "start": 133, "end": 148, "id": 27}, {"text": "and", "start": 149, "end": 152, "id": 28}, {"text": "a", "start": 153, "end": 154, "id": 29}, {"text": "collapsed", "start": 155, "end": 164, "id": 30}, {"text": "area", "start": 165, "end": 169, "id": 31}, {"text": "in", "start": 170, "end": 172, "id": 32}, {"text": "the", "start": 173, "end": 176, "id": 33}, {"text": "lower", "start": 177, "end": 182, "id": 34}, {"text": "pole", "start": 183, "end": 187, "id": 35}, {"text": "of", "start": 188, "end": 190, "id": 36}, {"text": "the", "start": 191, "end": 194, "id": 37}, {"text": "left", "start": 195, "end": 199, "id": 38}, {"text": "kidney", "start": 200, "end": 206, "id": 39}, {"text": ".", "start": 206, "end": 207, "id": 40}]}
{"pdf_hash": "7519c2ae226156555ce9cb89fbb4d9827ddd1323", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIG. 1. Preoperative computed tomography imaging. The contrast-enhanced coronal reformatted image depicts moderate enhancing fibrous tissue (arrow 2) with right ureteral stenosis (arrow 1).", "width": 1012, "height": 506, "subcaptions": {"b": [17, 18, 19, 20, 21, 22, 23, 24], "a": [32, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "e180bea6-29a0-4553-805e-b82491a7c170", "label": "a", "points": [[7.2, 3.2], [7.2, 502], [493.2, 502], [493.2, 3.2]], "color": "yellow"}, {"id": "82a570da-7de2-4ff6-ac08-3321ae14a3b8", "label": "b", "points": [[510.8, 0], [510.8, 503.6], [971.1, 503.6], [971.1, 0]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Preoperative", "start": 8, "end": 20, "id": 4}, {"text": "computed", "start": 21, "end": 29, "id": 5}, {"text": "tomography", "start": 30, "end": 40, "id": 6}, {"text": "imaging", "start": 41, "end": 48, "id": 7}, {"text": ".", "start": 48, "end": 49, "id": 8}, {"text": "The", "start": 50, "end": 53, "id": 9}, {"text": "contrast", "start": 54, "end": 62, "id": 10}, {"text": "-", "start": 62, "end": 63, "id": 11}, {"text": "enhanced", "start": 63, "end": 71, "id": 12}, {"text": "coronal", "start": 72, "end": 79, "id": 13}, {"text": "reformatted", "start": 80, "end": 91, "id": 14}, {"text": "image", "start": 92, "end": 97, "id": 15}, {"text": "depicts", "start": 98, "end": 105, "id": 16}, {"text": "moderate", "start": 106, "end": 114, "id": 17}, {"text": "enhancing", "start": 115, "end": 124, "id": 18}, {"text": "fibrous", "start": 125, "end": 132, "id": 19}, {"text": "tissue", "start": 133, "end": 139, "id": 20}, {"text": "(", "start": 140, "end": 141, "id": 21}, {"text": "arrow", "start": 141, "end": 146, "id": 22}, {"text": "2", "start": 147, "end": 148, "id": 23}, {"text": ")", "start": 148, "end": 149, "id": 24}, {"text": "with", "start": 150, "end": 154, "id": 25}, {"text": "right", "start": 155, "end": 160, "id": 26}, {"text": "ureteral", "start": 161, "end": 169, "id": 27}, {"text": "stenosis", "start": 170, "end": 178, "id": 28}, {"text": "(", "start": 179, "end": 180, "id": 29}, {"text": "arrow", "start": 180, "end": 185, "id": 30}, {"text": "1", "start": 186, "end": 187, "id": 31}, {"text": ")", "start": 187, "end": 188, "id": 32}, {"text": ".", "start": 188, "end": 189, "id": 33}]}
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{"pdf_hash": "ae587799f0c5e5739afbc2ab35b2815f942bb94f", "fig_key": "Figure13", "fig_uri": "11-Figure13-1.png", "text": "Fig. 13 Mucoepidermoid carcinoma. Coronal T2-W MRI (a) shows a hyperintense, well-defined left intra-parotid mass which is iso- to hyperintense on the axial T1 W view (b), and enhances avidly postcontrast (c). There are intratumoral cysts and necrosis, as well as associated bilateral cervical and posterior triangle lymphadenopathy", "width": 1246, "height": 458, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "c": [40, 41, 42, 43, 44, 45, 16, 17, 18, 19, 20, 21, 22, 23]}, "subfigures": [{"id": "3fffc1b9-ee3e-44ba-a2a9-bbb0df50868a", "label": "a", "points": [[35.4, 2], [35.4, 423.2], [417.3, 423.2], [417.3, 2]], "color": "yellow"}, {"id": "3c96d8d9-16e5-4329-b307-0e485fe8a6ab", "label": "b", "points": [[431.1, 0], [431.1, 421.2], [814.9, 421.2], [814.9, 0]], "color": "cyan"}, {"id": "986aa7f3-3b11-4c9d-9cda-53c552e32fc9", "label": "c", "points": [[826.7, 3.9], [826.7, 425.2], [1218.5, 425.2], [1218.5, 3.9]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "13", "start": 5, "end": 7, "id": 2}, {"text": "Mucoepidermoid", "start": 8, "end": 22, "id": 3}, {"text": "carcinoma", "start": 23, "end": 32, "id": 4}, {"text": ".", "start": 32, "end": 33, "id": 5}, {"text": "Coronal", "start": 34, "end": 41, "id": 6}, {"text": "T2-W", "start": 42, "end": 46, "id": 7}, {"text": "MRI", "start": 47, "end": 50, "id": 8}, {"text": "(", "start": 51, "end": 52, "id": 9}, {"text": "a", "start": 52, "end": 53, "id": 10}, {"text": ")", "start": 53, "end": 54, "id": 11}, {"text": "shows", "start": 55, "end": 60, "id": 12}, {"text": "a", "start": 61, "end": 62, "id": 13}, {"text": "hyperintense", "start": 63, "end": 75, "id": 14}, {"text": ",", "start": 75, "end": 76, "id": 15}, {"text": "well", "start": 77, "end": 81, "id": 16}, {"text": "-", "start": 81, "end": 82, "id": 17}, {"text": "defined", "start": 82, "end": 89, "id": 18}, {"text": "left", "start": 90, "end": 94, "id": 19}, {"text": "intra", "start": 95, "end": 100, "id": 20}, {"text": "-", "start": 100, "end": 101, "id": 21}, {"text": "parotid", "start": 101, "end": 108, "id": 22}, {"text": "mass", "start": 109, "end": 113, "id": 23}, {"text": "which", "start": 114, "end": 119, "id": 24}, {"text": "is", "start": 120, "end": 122, "id": 25}, {"text": "iso-", "start": 123, "end": 127, "id": 26}, {"text": "to", "start": 128, "end": 130, "id": 27}, {"text": "hyperintense", "start": 131, "end": 143, "id": 28}, {"text": "on", "start": 144, "end": 146, "id": 29}, {"text": "the", "start": 147, "end": 150, "id": 30}, {"text": "axial", "start": 151, "end": 156, "id": 31}, {"text": "T1", "start": 157, "end": 159, "id": 32}, {"text": "W", "start": 160, "end": 161, "id": 33}, {"text": "view", "start": 162, "end": 166, "id": 34}, {"text": "(", "start": 167, "end": 168, "id": 35}, {"text": "b", "start": 168, "end": 169, "id": 36}, {"text": ")", "start": 169, "end": 170, "id": 37}, {"text": ",", "start": 170, "end": 171, "id": 38}, {"text": "and", "start": 172, "end": 175, "id": 39}, {"text": "enhances", "start": 176, "end": 184, "id": 40}, {"text": "avidly", "start": 185, "end": 191, "id": 41}, {"text": "postcontrast", "start": 192, "end": 204, "id": 42}, {"text": "(", "start": 205, "end": 206, "id": 43}, {"text": "c", "start": 206, "end": 207, "id": 44}, {"text": ")", "start": 207, "end": 208, "id": 45}, {"text": ".", "start": 208, "end": 209, "id": 46}, {"text": "There", "start": 210, "end": 215, "id": 47}, {"text": "are", "start": 216, "end": 219, "id": 48}, {"text": "intratumoral", "start": 220, "end": 232, "id": 49}, {"text": "cysts", "start": 233, "end": 238, "id": 50}, {"text": "and", "start": 239, "end": 242, "id": 51}, {"text": "necrosis", "start": 243, "end": 251, "id": 52}, {"text": ",", "start": 251, "end": 252, "id": 53}, {"text": "as", "start": 253, "end": 255, "id": 54}, {"text": "well", "start": 256, "end": 260, "id": 55}, {"text": "as", "start": 261, "end": 263, "id": 56}, {"text": "associated", "start": 264, "end": 274, "id": 57}, {"text": "bilateral", "start": 275, "end": 284, "id": 58}, {"text": "cervical", "start": 285, "end": 293, "id": 59}, {"text": "and", "start": 294, "end": 297, "id": 60}, {"text": "posterior", "start": 298, "end": 307, "id": 61}, {"text": "triangle", "start": 308, "end": 316, "id": 62}, {"text": "lymphadenopathy", "start": 317, "end": 332, "id": 63}]}
{"pdf_hash": "fa5cb5366416770afb23ba967160da18fd47bfa8", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Figure 3. FIB/SEM tomography of an HCMV infected nucleus five days post infection. (A-D) Volume 1; (E-F) Volume 2; (A,E) Single FIB/SEM micrographs. High contrast allows identification of membranes and nuclear capsids. Nuclear membrane structures (infoldings) are visible close to the nuclear envelope (see also Movies S1 and S2). nu nucleoplasm, cy cytoplasm. Dimensions of each volume: 6.4 \u00b5m\u02c65.5 \u00b5m\u02c65 \u00b5m; (B) Xz view of the tomogram of volume 1. The dashed line marks the position of the FIB/SEM image shown in (A). (C,D,F) Three-dimensional reconstructions of the inner nuclear membrane with infoldings (blue, semi-transparent) and capsids (nucleoplasm: A capsids pink; B capsids blue; C capsids white; infoldings: A capsids purple; B capsids orange; C capsids green). See also Movies S3 and S4. (C and D) Volume 1 contains 4160 capsids. (E) The dashed line marks a replication center. (F) Infolding D has no connection to the inner nuclear membrane. Infolding E consists of tubular and spherical segments. Volume 2 contains 1338 capsids. 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{"pdf_hash": "c774f5949642db0e3a64bf487f46ee3a1b223e35", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. EFTF-expressing pluripotent cells form eye-like structures in tadpole flank. (A) Schematic illustrating the expected retinal layers of the eye including the outer nuclear (ONL), inner nuclear (INL), and ganglion cell (GCL) layers. The mitotically active CMZ is indicated in red. (B) Transverse section of a stage 41 wild-type retina. Dashed lines mark the location of the plexiform layers. The eye is oriented so that dorsal is to the left. (C\u2013G) Flank eyes expressed YFP throughout, contained an RPE and a trilayered morphology with putative inner and outer plexiform layers (dashed lines in D\u2013H). Markers were used to detect retinal cell classes. (C) Whole tadpole bright field image overlayed with fluorescent image, showing flank eye (yellow box) on top of gut (dashed line). Inlay is a magnified view of the boxed flank eye. (D) Cryostat section (12 mm) shows cells labeled for the retinal ganglion cell (RGC) marker, hermes, by in situ hybridization. (E) R5 antibody labels Mu\u0308ller glia (Mu\u0308; red), which extend processes the breadth of the flank retina. (F) GABA labels horizontal and amacrine cells (HC, AM; red) of the INL. (G) Cells expressing YFP (green) co-express the cone photoreceptor (cPR) marker Calbindin (yellow). (H) Cells expressing the rod photoreceptor marker XAP2 (rPR; red); BrdU-immunoreactivity (yellow) identifies mitotically active cells in the periphery of the same flank retina. 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{"pdf_hash": "4a56d671c5a497b54889d48052b81b08eb9bf3eb", "fig_key": "Figure6", "fig_uri": "28-Figure6-1.png", "text": "Figure 6: The first three estimated eigenimages for the longitudinal difference. Each eigenimage is represented by eleven equidistant axial slices. Negative loadings are depicted in red, positive ones are in blue.", "width": 1008, "height": 1610, "subcaptions": null, "subfigures": [{"id": "691c2b92-557d-4984-ab84-d409c736c529", "label": "a", "points": [[19.4, 10.6], [19.4, 257.4], [987.6, 257.4], [987.6, 10.6]], "color": "yellow"}, {"id": "65aa7350-ab44-4cd4-9689-6f8d99512a29", "label": "b", "points": [[11.4, 270.2], [11.4, 512.2], [987.6, 512.2], [987.6, 270.2]], "color": "cyan"}, {"id": "2d435767-39b6-4326-96c0-fd110d20d929", "label": "c", "points": [[17.8, 534.5], [17.8, 798.9], [981.2, 798.9], [981.2, 534.5]], "color": "magenta"}, {"id": "71cf921c-59fd-41a3-9a2c-9e8a4441b076", "label": "d", "points": [[14.6, 805.2], [14.6, 1048.9], [995.5, 1048.9], [995.5, 805.2]], "color": "springgreen"}, {"id": "e1d0718f-d483-4328-8ea4-a12c6b8b9728", "label": "e", "points": [[21, 1085.5], [21, 1333.9], [987.6, 1333.9], [987.6, 1085.5]], "color": "tomato"}, {"id": "9e82dc63-bae1-4cc2-bbdc-15b84d62687a", "label": "f", "points": [[13, 1337.6], [13, 1594], [995.5, 1594], [995.5, 1337.6]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "The", "start": 10, "end": 13, "id": 3}, {"text": "first", "start": 14, "end": 19, "id": 4}, {"text": "three", "start": 20, "end": 25, "id": 5}, {"text": "estimated", "start": 26, "end": 35, "id": 6}, {"text": "eigenimages", "start": 36, "end": 47, "id": 7}, {"text": "for", "start": 48, "end": 51, "id": 8}, {"text": "the", "start": 52, "end": 55, "id": 9}, {"text": "longitudinal", "start": 56, "end": 68, "id": 10}, {"text": "difference", "start": 69, "end": 79, "id": 11}, {"text": ".", "start": 79, "end": 80, "id": 12}, {"text": "Each", "start": 81, "end": 85, "id": 13}, {"text": "eigenimage", "start": 86, "end": 96, "id": 14}, {"text": "is", "start": 97, "end": 99, "id": 15}, {"text": "represented", "start": 100, "end": 111, "id": 16}, {"text": "by", "start": 112, "end": 114, "id": 17}, {"text": "eleven", "start": 115, "end": 121, "id": 18}, {"text": "equidistant", "start": 122, "end": 133, "id": 19}, {"text": "axial", "start": 134, "end": 139, "id": 20}, {"text": "slices", "start": 140, "end": 146, "id": 21}, {"text": ".", "start": 146, "end": 147, "id": 22}, {"text": "Negative", "start": 148, "end": 156, "id": 23}, {"text": "loadings", "start": 157, "end": 165, "id": 24}, {"text": "are", "start": 166, "end": 169, "id": 25}, {"text": "depicted", "start": 170, "end": 178, "id": 26}, {"text": "in", "start": 179, "end": 181, "id": 27}, {"text": "red", "start": 182, "end": 185, "id": 28}, {"text": ",", "start": 185, "end": 186, "id": 29}, {"text": "positive", "start": 187, "end": 195, "id": 30}, {"text": "ones", "start": 196, "end": 200, "id": 31}, {"text": "are", "start": 201, "end": 204, "id": 32}, {"text": "in", "start": 205, "end": 207, "id": 33}, {"text": "blue", "start": 208, "end": 212, "id": 34}, {"text": ".", "start": 212, "end": 213, "id": 35}]}
{"pdf_hash": "d78760e8b5e5cf72f97cf1fa596e83314bb11929", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. This window shows the process for generating a virtual lateral cephalogram from a 3D volume-rendering image using a cone-beam computed tomography scan with Reference Ear Plug (REP). The virtual central ray is geometrized using the right and left titanium ball markers of the REP (top left and right). Using the function of the program, a virtual lateral cephalogram is created (bottom right).", "width": 1042, "height": 810, "subcaptions": {"a": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "c": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 61, 62, 63]}, "subfigures": [{"id": "3ca16802-5dd7-4f26-8306-8c21c6a83121", "label": "a", "points": [[41.4, 0.5], [41.4, 384.1], [520.5, 384.1], [520.5, 0.5]], "color": "yellow"}, {"id": "01c7366c-a346-4e87-b704-4fe5c8cbcb51", "label": "a", "points": [[532, 13.7], [532, 389], [994.5, 389], [994.5, 13.7]], "color": "cyan"}, {"id": "003fbfb5-9a88-4179-88a0-06153428f46c", "label": "b", "points": [[44.7, 395.6], [44.7, 785.8], [512.2, 785.8], [512.2, 395.6]], "color": "magenta"}, {"id": "a63753f5-8153-408c-9cf3-5857ff9e88ab", "label": "c", "points": [[532, 397.3], [532, 787.4], [1014.3, 787.4], [1014.3, 397.3]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 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{"pdf_hash": "bdf35bc3c3be21feb5148eeb910d9c517d1c7d62", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Representative micrographs of the ipsilateral synchronous mammary fibroepithelial lesions evaluated in this study. Representative micrographs of three fibroadenomas (FAs) (a\u2013c), one benign phyllodes tumor (PT) (d), and one malignant PT (e). Two FAs (a,b) displayed a predominant pericanalicular pattern and a stromal component with usual cellularity, and no atypia or mitoses. The third FA had an intracanalicular growth pattern and hyalinized stroma (c). The benign and malignant PTs were characterized by leaf-like architecture (d,e). The benign PT showed moderate stromal cellularity, no significant nuclear pleomorphism, and inconspicuous mitotic activity (0 mitoses per 10 high-power fields (HPFs) (d); Supplementary Table 1), whereas the malignant PT displayed stromal expansion with marked hypercellularity (e), moderate nuclear atypia, and mitotic activity (10 mitoses per 10 HPFs (f); Supplementary Table 1). The epithelium did not show atypia nor did it show significant proliferation in all lesions.", "width": 1404, "height": 1548, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75], "c": [17, 18, 19, 20, 21, 22, 23, 24, 25, 28, 29, 49, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90], "d": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 17, 18, 19, 145, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 49, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "e": [17, 18, 19, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 43, 44, 45, 46, 47, 48, 49, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 106, 107, 108], "f": [148, 149, 150, 151, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 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{"pdf_hash": "2c3b9acebe208a4f3c530f8d7b3d3848a2e0d066", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Preoperative (1a) and postoperative (1b) head CT scans in a 5-month-old infant with EDH", "width": 1340, "height": 516, "subcaptions": {"a": [4, 5, 6, 7], "b": [9, 10, 11, 12]}, "subfigures": [{"id": "710190e8-cf4e-42d9-a465-3a8dad8b4f09", "label": "a", "points": [[44.5, 78.3], [44.5, 440.3], [495.4, 440.3], [495.4, 78.3]], "color": "yellow"}, {"id": "bd013a04-34bc-4d30-834b-446ad534d368", "label": "b", "points": [[502.3, 72.2], [502.3, 439.6], [1296.5, 439.6], [1296.5, 72.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Preoperative", "start": 8, "end": 20, "id": 4}, {"text": "(", "start": 21, "end": 22, "id": 5}, {"text": "1a", "start": 22, "end": 24, "id": 6}, {"text": ")", "start": 24, "end": 25, "id": 7}, {"text": "and", "start": 26, "end": 29, "id": 8}, {"text": "postoperative", "start": 30, "end": 43, "id": 9}, {"text": "(", "start": 44, "end": 45, "id": 10}, {"text": "1b", "start": 45, "end": 47, "id": 11}, {"text": ")", "start": 47, "end": 48, "id": 12}, {"text": "head", "start": 49, "end": 53, "id": 13}, {"text": "CT", "start": 54, "end": 56, "id": 14}, {"text": "scans", "start": 57, "end": 62, "id": 15}, {"text": "in", "start": 63, "end": 65, "id": 16}, {"text": "a", "start": 66, "end": 67, "id": 17}, {"text": "5-month", "start": 68, "end": 75, "id": 18}, {"text": "-", "start": 75, "end": 76, "id": 19}, {"text": "old", "start": 76, "end": 79, "id": 20}, {"text": "infant", "start": 80, "end": 86, "id": 21}, {"text": "with", "start": 87, "end": 91, "id": 22}, {"text": "EDH", "start": 92, "end": 95, "id": 23}]}
{"pdf_hash": "bcbd0ef6b5ec48f912c9e0c791312cbdbe2d2dc8", "fig_key": "Figure4", "fig_uri": "10-Figure4-1.png", "text": "Fig. 4. Darkfield photomicrograph of a transverse section through the forebrain showing patterns of labeling in the amygdala produced by an injection in the infralimbic cortex (case 701). Note pronounced labeling in the central (A), medial (A,B), and basomedial (A,B) nuclei, and an essential absence of labeling in the lateral and basolateral nuclei, lateral to the central nucleus. 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{"pdf_hash": "4681f89c1cc402d7dd225df306a395535b5335d8", "fig_key": "Figure3", "fig_uri": "10-Figure3-1.png", "text": "Figure 3 Brain MRI characteristics. Sagittal T1- (A, D, G and J), coronal T2- (B, E, H and K), and axial T2-weighted spin echo images (C, F, I and L). Axial and coronal sections in SPG11 (A\u2013C, Patient 2055) show the increased signal intensity in the region of the forceps minor of the corpus callosum, (arrows in B and C), with a \u2018ears of the lynx\u2019 appearance (C), not visible in SPG15 (D\u2013F Patient 654). In SPG11 a dramatic enlargement of the interhemispheric and frontal sulci (B), despite a quite normal cerebellar volume is visible. In SPG35 (G\u2013I, Patient 73), diffuse cerebral atrophy, global cerebellar atrophy (H and I), thin corpus callosum (G), and periventricular white matter hyperintensity is visible (arrowheads in I). 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{"pdf_hash": "a3cab7c3320c1cacff132bee24f0249841df49a2", "fig_key": "Figure2", "fig_uri": "8-Figure2-1.png", "text": "Figure 2 Brain activity detected by the ASMR-eliciting > control video contrasts. The results in parts (A), (B), and (C) show the responses of ASMR participants while viewing ASMR-eliciting > control videos. The peak intensity coordinates for each significantly increased cluster were located in the right superior frontal gyrus, dorsal anterior cingulate gyrus, and precentral gyrus, and the left cuneus, medial frontal, precentral, and superior temporal gyri. (A) Sagittal view. (B) Coronal view. (C) Transverse view. The results in parts (D), (E), and (F) depict the contrast showing responses of the control participants while viewing ASMR-eliciting > control videos. Control participants showed significantly decreased activity in the right cuneus while watching the ASMR-eliciting videos, as compared to watching the control videos. (D) Sagittal view. (E) Coronal view. (F) Transverse view. Contrasts are displayed at p < 0.01, cluster threshold corrected for multiple comparisons. SAG, sagittal; COR, coronal; TRA, transverse; A, anterior; P, posterior; R, right; L, left. 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{"pdf_hash": "bbcfdb7e9017c8777c528938295f93ad8f8b6382", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: CT scan of the patient showing the primary tumor in the subglottic region.", "width": 1002, "height": 1018, "subcaptions": null, "subfigures": [{"id": "b113c878-5f53-48c3-a5c8-bf8c1d76cb43", "label": "a", "points": [[6.6, 78.6], [6.6, 441.1], [486.2, 441.1], [486.2, 78.6]], "color": "yellow"}, {"id": "d4d6f4b9-7d38-49ea-9963-896883b3f91c", "label": "c", "points": [[521.1, 69.1], [521.1, 428.5], [999.1, 428.5], [999.1, 69.1]], "color": "cyan"}, {"id": "61c121d0-6b87-473e-aa25-b8bf2fad2ced", "label": "c", "points": [[0.3, 485.4], [0.3, 949.2], [494.1, 949.2], [494.1, 485.4]], "color": "magenta"}, {"id": "6cc793d9-c535-418f-8bc4-2abaab6a6320", "label": "d", "points": [[521.1, 490.2], [521.1, 942.9], [995.9, 942.9], [995.9, 490.2]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "scan", "start": 13, "end": 17, "id": 4}, {"text": "of", "start": 18, "end": 20, "id": 5}, {"text": "the", "start": 21, "end": 24, "id": 6}, {"text": "patient", "start": 25, "end": 32, "id": 7}, {"text": "showing", "start": 33, "end": 40, "id": 8}, {"text": "the", "start": 41, "end": 44, "id": 9}, {"text": "primary", "start": 45, "end": 52, "id": 10}, {"text": "tumor", "start": 53, "end": 58, "id": 11}, {"text": "in", "start": 59, "end": 61, "id": 12}, {"text": "the", "start": 62, "end": 65, "id": 13}, {"text": "subglottic", "start": 66, "end": 76, "id": 14}, {"text": "region", "start": 77, "end": 83, "id": 15}, {"text": ".", "start": 83, "end": 84, "id": 16}]}
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{"pdf_hash": "eb2e3fdb51f2bd7c5d02f97e3be74ce90f1a885f", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Axial (a) and coronal (b) view of 3DCT before treatment. The atlas was rotated without dislocation of the odontoid process in axial view. The axis showed slight oblique position against atlas in coronal view.", "width": 950, "height": 452, "subcaptions": {"a": [3, 4, 5, 6, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43]}, "subfigures": [{"id": "0dd860bb-8198-4dd4-a395-1d49e1336294", "label": "a", "points": [[0, 0], [0, 379.7], [448.7, 379.7], [448.7, 0]], "color": "yellow"}, {"id": "245d9089-da26-4b59-81de-02e18da3bada", "label": "b", "points": [[478.8, 0], [478.8, 378.2], [945.5, 378.2], [945.5, 0]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Axial", "start": 10, "end": 15, "id": 3}, {"text": "(", "start": 16, "end": 17, "id": 4}, {"text": "a", "start": 17, "end": 18, "id": 5}, {"text": ")", "start": 18, "end": 19, "id": 6}, {"text": "and", "start": 20, "end": 23, "id": 7}, {"text": "coronal", "start": 24, "end": 31, "id": 8}, {"text": "(", "start": 32, "end": 33, "id": 9}, {"text": "b", "start": 33, "end": 34, "id": 10}, {"text": ")", "start": 34, "end": 35, "id": 11}, {"text": "view", "start": 36, "end": 40, "id": 12}, {"text": "of", "start": 41, "end": 43, "id": 13}, {"text": "3DCT", "start": 44, "end": 48, "id": 14}, {"text": "before", "start": 49, "end": 55, "id": 15}, {"text": "treatment", "start": 56, "end": 65, "id": 16}, {"text": ".", "start": 65, "end": 66, "id": 17}, {"text": "The", "start": 67, "end": 70, "id": 18}, {"text": "atlas", "start": 71, "end": 76, "id": 19}, {"text": "was", "start": 77, "end": 80, "id": 20}, {"text": "rotated", "start": 81, "end": 88, "id": 21}, {"text": "without", "start": 89, "end": 96, "id": 22}, {"text": "dislocation", "start": 97, "end": 108, "id": 23}, {"text": "of", "start": 109, "end": 111, "id": 24}, {"text": "the", "start": 112, "end": 115, "id": 25}, {"text": "odontoid", "start": 116, "end": 124, "id": 26}, {"text": "process", "start": 125, "end": 132, "id": 27}, {"text": "in", "start": 133, "end": 135, "id": 28}, {"text": "axial", "start": 136, "end": 141, "id": 29}, {"text": "view", "start": 142, "end": 146, "id": 30}, {"text": ".", "start": 146, "end": 147, "id": 31}, {"text": "The", "start": 148, "end": 151, "id": 32}, {"text": "axis", "start": 152, "end": 156, "id": 33}, {"text": "showed", "start": 157, "end": 163, "id": 34}, {"text": "slight", "start": 164, "end": 170, "id": 35}, {"text": "oblique", "start": 171, "end": 178, "id": 36}, {"text": "position", "start": 179, "end": 187, "id": 37}, {"text": "against", "start": 188, "end": 195, "id": 38}, {"text": "atlas", "start": 196, "end": 201, "id": 39}, {"text": "in", "start": 202, "end": 204, "id": 40}, {"text": "coronal", "start": 205, "end": 212, "id": 41}, {"text": "view", "start": 213, "end": 217, "id": 42}, {"text": ".", "start": 217, "end": 218, "id": 43}]}
{"pdf_hash": "82353c71b7143df536adb26eeceb9d659f0ae3ea", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Abdomen CT axial (A) and coronal (B) images showing a 2.7\u00d72.4-cm, lobulated, enhancing lesion at the pancreas head (open arrow).", "width": 900, "height": 444, "subcaptions": {"a": [8, 5, 6, 7], "b": [10, 11, 12, 13]}, "subfigures": [{"id": "aa7106ba-0b00-47c8-b6e3-b70ee569fbe9", "label": "a", "points": [[4.3, 2.8], [4.3, 439.4], [459.3, 439.4], [459.3, 2.8]], "color": "yellow"}, {"id": "47e9e3a7-32de-4df1-b7e3-889cdde5688e", "label": "b", "points": [[467.8, 1.4], [467.8, 437.9], [895.8, 437.9], [895.8, 1.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Abdomen", "start": 10, "end": 17, "id": 3}, {"text": "CT", "start": 18, "end": 20, "id": 4}, {"text": "axial", "start": 21, "end": 26, "id": 5}, {"text": "(", "start": 27, "end": 28, "id": 6}, {"text": "A", "start": 28, "end": 29, "id": 7}, {"text": ")", "start": 29, "end": 30, "id": 8}, {"text": "and", "start": 31, "end": 34, "id": 9}, {"text": "coronal", "start": 35, "end": 42, "id": 10}, {"text": "(", "start": 43, "end": 44, "id": 11}, {"text": "B", "start": 44, "end": 45, "id": 12}, {"text": ")", "start": 45, "end": 46, "id": 13}, {"text": "images", "start": 47, "end": 53, "id": 14}, {"text": "showing", "start": 54, "end": 61, "id": 15}, {"text": "a", "start": 62, "end": 63, "id": 16}, {"text": "2.7\u00d72.4-cm", "start": 64, "end": 74, "id": 17}, {"text": ",", "start": 74, "end": 75, "id": 18}, {"text": "lobulated", "start": 76, "end": 85, "id": 19}, {"text": ",", "start": 85, "end": 86, "id": 20}, {"text": "enhancing", "start": 87, "end": 96, "id": 21}, {"text": "lesion", "start": 97, "end": 103, "id": 22}, {"text": "at", "start": 104, "end": 106, "id": 23}, {"text": "the", "start": 107, "end": 110, "id": 24}, {"text": "pancreas", "start": 111, "end": 119, "id": 25}, {"text": "head", "start": 120, "end": 124, "id": 26}, {"text": "(", "start": 125, "end": 126, "id": 27}, {"text": "open", "start": 126, "end": 130, "id": 28}, {"text": "arrow", "start": 131, "end": 136, "id": 29}, {"text": ")", "start": 136, "end": 137, "id": 30}, {"text": ".", "start": 137, "end": 138, "id": 31}]}
{"pdf_hash": "f809285e36319f40e8c4b98566bd5c5f63537a1b", "fig_key": "Figure8", "fig_uri": "5-Figure8-1.png", "text": "Figure 8: Joint contamination in osteomyelitis. Schematic drawings (a) and (b), coronal (c) and axial (d) T1\u2013WI Fat\u2013Sat after gadolinium contrast administration. (a) shows a joint in which the joint capsule (blue) is attaching underneath the growth plate. This intra-articular location of the growth plate may lead to rapid spread of infection into the adjacent joint. (b) shows a joint in which the joint capsule (blue) is attaching above the growth plate. An extra-articularly located growth plate protects against early joint contamination. (c, d). Example on MRI of a patient with rapid spread of the infectious focus to the adjacent left shoulder joint. 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{"pdf_hash": "2157ca07d63bfec04257ad13ac6f22e01698322a", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIGURE 2 Associated SPECT/CT images (axial, coronal, and sagittal views) localizing the abnormal focal activity to the distal paraesophageal region (arrows).", "width": 894, "height": 1256, "subcaptions": {"a": [8]}, "subfigures": [{"id": "3267e09e-cde5-455f-937d-6f1a9f0a9002", "label": "a", "points": [[3.2, 1.2], [3.2, 625.4], [891.5, 625.4], [891.5, 1.2]], "color": "yellow"}, {"id": "07ca87cd-a148-4451-984e-cffa215500b2", "label": "b", "points": [[11.7, 644.5], [11.7, 1236.2], [472.1, 1236.2], [472.1, 644.5]], "color": "cyan"}, {"id": "00a1ebb6-f57b-431b-b934-0d4eba64fc44", "label": "c", "points": [[490.5, 643.1], [490.5, 1224.9], [893, 1224.9], [893, 643.1]], "color": "magenta"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Associated", "start": 9, "end": 19, "id": 2}, {"text": "SPECT", "start": 20, "end": 25, "id": 3}, {"text": "/", "start": 25, "end": 26, "id": 4}, {"text": "CT", "start": 26, "end": 28, "id": 5}, {"text": "images", "start": 29, "end": 35, "id": 6}, {"text": "(", "start": 36, "end": 37, "id": 7}, {"text": "axial", "start": 37, "end": 42, "id": 8}, {"text": ",", "start": 42, "end": 43, "id": 9}, {"text": "coronal", "start": 44, "end": 51, "id": 10}, {"text": ",", "start": 51, "end": 52, "id": 11}, {"text": "and", "start": 53, "end": 56, "id": 12}, {"text": "sagittal", "start": 57, "end": 65, "id": 13}, {"text": "views", "start": 66, "end": 71, "id": 14}, {"text": ")", "start": 71, "end": 72, "id": 15}, {"text": "localizing", "start": 73, "end": 83, "id": 16}, {"text": "the", "start": 84, "end": 87, "id": 17}, {"text": "abnormal", "start": 88, "end": 96, "id": 18}, {"text": "focal", "start": 97, "end": 102, "id": 19}, {"text": "activity", "start": 103, "end": 111, "id": 20}, {"text": "to", "start": 112, "end": 114, "id": 21}, {"text": "the", "start": 115, "end": 118, "id": 22}, {"text": "distal", "start": 119, "end": 125, "id": 23}, {"text": "paraesophageal", "start": 126, "end": 140, "id": 24}, {"text": "region", "start": 141, "end": 147, "id": 25}, {"text": "(", "start": 148, "end": 149, "id": 26}, {"text": "arrows", "start": 149, "end": 155, "id": 27}, {"text": ")", "start": 155, "end": 156, "id": 28}, {"text": ".", "start": 156, "end": 157, "id": 29}]}
{"pdf_hash": "1fa5047279de6c7a0573c8727467cc904eb4d24d", "fig_key": "Figure9", "fig_uri": "13-Figure9-1.png", "text": "Figure 9. Overlapping hypo connectivity patterns for thalamus and midbrain in schizophrenia. Overlap and distinct patterns of hypo connectivity with thalamus (red) and SN (blue) for 69 schizophrenia patients versus 74 healthy controls at P , 0.001, superimposed on axial and coronal views of the human brain. 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{"pdf_hash": "4c40971454c277768227bedbb1c37897c331741f", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Figure 2 Regions (predominantly dorsal) in which RTD is associated with decreased rCBF, independent of subjective mood change. SPM99 T-maps (top row) are projected onto the high-resolution 152-subject average T1-weighted MRI image (bottom row). One significant cluster (p\u00bc 0.013) was found, in dorsal anterior cingulate cortex (BA 32). 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{"pdf_hash": "c6e56d7cc40ebfea5711815375a218c70cf08b77", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. A gadolinium enhanced temporal magnetic resonance imaging scan shows a homogenous enhanced mass in the left posterior petrous region (arrow).", "width": 662, "height": 348, "subcaptions": null, "subfigures": [{"id": "d1869d81-62f4-4fbc-891a-c040799057cf", "label": "a", "points": [[1.2, 0.3], [1.2, 311], [310.8, 311], [310.8, 0.3]], "color": "yellow"}, {"id": "c34dae56-c817-42b2-a3f1-09208ffb1fc9", "label": "b", "points": [[330.7, 4.5], [330.7, 316.2], [655.9, 316.2], [655.9, 4.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": "gadolinium", "start": 10, "end": 20, "id": 5}, {"text": "enhanced", "start": 21, "end": 29, "id": 6}, {"text": "temporal", "start": 30, "end": 38, "id": 7}, {"text": "magnetic", "start": 39, "end": 47, "id": 8}, {"text": "resonance", "start": 48, "end": 57, "id": 9}, {"text": "imaging", "start": 58, "end": 65, "id": 10}, {"text": "scan", "start": 66, "end": 70, "id": 11}, {"text": "shows", "start": 71, "end": 76, "id": 12}, {"text": "a", "start": 77, "end": 78, "id": 13}, {"text": "homogenous", "start": 79, "end": 89, "id": 14}, {"text": "enhanced", "start": 90, "end": 98, "id": 15}, {"text": "mass", "start": 99, "end": 103, "id": 16}, {"text": "in", "start": 104, "end": 106, "id": 17}, {"text": "the", "start": 107, "end": 110, "id": 18}, {"text": "left", "start": 111, "end": 115, "id": 19}, {"text": "posterior", "start": 116, "end": 125, "id": 20}, {"text": "petrous", "start": 126, "end": 133, "id": 21}, {"text": "region", "start": 134, "end": 140, "id": 22}, {"text": "(", "start": 141, "end": 142, "id": 23}, {"text": "arrow", "start": 142, "end": 147, "id": 24}, {"text": ")", "start": 147, "end": 148, "id": 25}, {"text": ".", "start": 148, "end": 149, "id": 26}]}
{"pdf_hash": "e3c00274cf819fd634698a8635fba14d6901ac55", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Figure 4. Example of a false positive CCTA examination. This 63 years old male patient underwent stress nuclear myocardial perfusion imaging because of exertional dyspnea. Stress images in the vertical short axis (B) and horizontal short axis views (D) are suggestive of decreased perfusion to the lateral wall of the left ventricle (arrow heads), which is reversible at rest (A,C). The examination was thus interpreted as concerning for lateral wall ischemia. At CCTA, transverse section (E) and curved multiplanar reformat (F) of the right coronary artery were interpreted as showing 50% stenosis with focal soft plaque (arrow). No luminal narrowing is noted in the left anterior descending (G) and circumflex (H) arteries. On catheter angiograms (I,K), there is no evidence of luminal narrowing in any vessel. The false positive finding on CCTA likely represents an artifact. 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{"pdf_hash": "057ed12be6d7a6a4c9bd62945e39cf7068482bcc", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Transverse computed tomography images at the level of the mid-caudal lung lobes in a sheep that was pre-treated with 150 mg/kg vatinoxan (VAT + DEX) or saline and 10 min later received 3 mg/kg dexmedetomidine (DEX): at baseline (BL) and at 20 min (T20) (A, B; DEX), and at 2 min before (T-2) and at 20 min after (T20) dexmedetomidine (C, D; VAT + DEX). Note that, in image (A), the arrows point to the caudal pulmonary vein (blue) and artery (red), whereas the circles 1 and 2 indicate the regions of interest (ROI).", "width": 1066, "height": 1158, "subcaptions": {"a": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 69, 70, 71, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "b": [64, 65, 68, 69, 70, 71, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63], "c": [74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 94, 95, 96, 97, 98], "d": [74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 93, 94, 95, 96, 97, 98]}, "subfigures": [{"id": "cba0cbe2-7792-4485-a931-f1c0c733bb4e", "label": "a", "points": [[41.3, 6.5], [41.3, 558.8], [521.2, 558.8], [521.2, 6.5]], "color": "yellow"}, {"id": "5019f2e9-4638-400a-b476-241d013624bf", "label": "b", 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{"pdf_hash": "347259dfa3d1b694dfc33f5afcd543d36d735ece", "fig_key": "Figure7", "fig_uri": "11-Figure7-1.png", "text": "Figure 7. Visualization of telomeric DNA in HeLa-L nuclei and nuclear matrices by EM-ISH. For the isolation of permeabilized nuclei (A-D), cells were extracted in situ with Triton X-100 for either 3 (A-C) or 10 min (D), digested with RNase A, and fixed with 4% formaldehyde plus 0.05 % glutaraldehyde. For the isolation of nuclear matrices (E) cells were permeabilized with digitonin, stabilized at 37\u00b0C in the presence of Cu 2\u00f7 ions, and extracted with LIS. Resulting nuclear halos were digested with PvulI plus Hinfl and fixed with 4% formaldehyde plus 0.05% glutaraldehyde. Preparations were hybridized with a biotin-labeled [CCCUAA]27 RNA probe, and hybrids were visualized by immunolabeling using an anti-biotin primary antibody and a secondary antibody coupled to ultrasmall gold particles. Gold particles were enlarged by silver enhancement, and preparations were embedded and cut into 280-nm thick sections. N, nucleus; Nu, nucleolus; C, cytoskeletal element; Ig, interchromatin granule cluster. 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{"pdf_hash": "8f69af205f33bae757fbafef37300351dd835cb9", "fig_key": "Figure8", "fig_uri": "7-Figure8-1.png", "text": "FIGURE 8: Injection of dominant-negative constructs of FAK and control proteins (FATD:GFP, FAK:GFP, GFP). (A, B) Unfertilized eggs injected with high concentrations of FATD:GFP and fixed 4 h postfertilization. Ectopic actin and aberrant nuclear morphology resulted. 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{"pdf_hash": "adbe00f8c3c3bdfc15d44d3bc0122828436c92bd", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. - Pre-op. CT scan with iodized non ionic contrast medium showing a 3 cm in diameter nodular shadow in the upper segment of the lingula abutting the pleura, with irregular border and light hyperdensity.", "width": 1340, "height": 506, "subcaptions": null, "subfigures": [{"id": "52e1ebde-60d5-48f6-b4eb-9942092ae141", "label": "a", "points": [[17.3, 11.3], [17.3, 483.4], [643.9, 483.4], [643.9, 11.3]], "color": "yellow"}, {"id": "8a4b8cbc-a85b-41fe-9968-14c27e982449", "label": "b", "points": [[718, 19.8], [718, 487.6], [1323.5, 487.6], [1323.5, 19.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "-", "start": 8, "end": 9, "id": 4}, {"text": "Pre", "start": 10, "end": 13, "id": 5}, {"text": "-", "start": 13, "end": 14, "id": 6}, {"text": "op", "start": 14, "end": 16, "id": 7}, {"text": ".", "start": 16, "end": 17, "id": 8}, {"text": "CT", "start": 18, "end": 20, "id": 9}, {"text": "scan", "start": 21, "end": 25, "id": 10}, {"text": "with", "start": 26, "end": 30, "id": 11}, {"text": "iodized", "start": 31, "end": 38, "id": 12}, {"text": "non", "start": 39, "end": 42, "id": 13}, {"text": "ionic", "start": 43, "end": 48, "id": 14}, {"text": "contrast", "start": 49, "end": 57, "id": 15}, {"text": "medium", "start": 58, "end": 64, "id": 16}, {"text": "showing", "start": 65, "end": 72, "id": 17}, {"text": "a", "start": 73, "end": 74, "id": 18}, {"text": "3", "start": 75, "end": 76, "id": 19}, {"text": "cm", "start": 77, "end": 79, "id": 20}, {"text": "in", "start": 80, "end": 82, "id": 21}, {"text": "diameter", "start": 83, "end": 91, "id": 22}, {"text": "nodular", "start": 92, "end": 99, "id": 23}, {"text": "shadow", "start": 100, "end": 106, "id": 24}, {"text": "in", "start": 107, "end": 109, "id": 25}, {"text": "the", "start": 110, "end": 113, "id": 26}, {"text": "upper", "start": 114, "end": 119, "id": 27}, {"text": "segment", "start": 120, "end": 127, "id": 28}, {"text": "of", "start": 128, "end": 130, "id": 29}, {"text": "the", "start": 131, "end": 134, "id": 30}, {"text": "lingula", "start": 135, "end": 142, "id": 31}, {"text": "abutting", "start": 143, "end": 151, "id": 32}, {"text": "the", "start": 152, "end": 155, "id": 33}, {"text": "pleura", "start": 156, "end": 162, "id": 34}, {"text": ",", "start": 162, "end": 163, "id": 35}, {"text": "with", "start": 164, "end": 168, "id": 36}, {"text": "irregular", "start": 169, "end": 178, "id": 37}, {"text": "border", "start": 179, "end": 185, "id": 38}, {"text": "and", "start": 186, "end": 189, "id": 39}, {"text": "light", "start": 190, "end": 195, "id": 40}, {"text": "hyperdensity", "start": 196, "end": 208, "id": 41}, {"text": ".", "start": 208, "end": 209, "id": 42}]}
{"pdf_hash": "64ace584e78e20d665782612adea97c6dbbebcad", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. MRI findings of the mass. The gadolinium-enhanced T1 weighted images showed a posterior pharyngeal wall mass with central enhancement and hypointense portions (arrows).", "width": 662, "height": 450, "subcaptions": null, "subfigures": [{"id": "231e1d98-797e-4fa1-90b3-b748e2896105", "label": "a", "points": [[1.2, 2.4], [1.2, 448], [296.2, 448], [296.2, 2.4]], "color": "yellow"}, {"id": "cec4c54e-2c00-44de-af53-6934522a0626", "label": "b", "points": [[312.9, 2.4], [312.9, 444.8], [661.2, 444.8], [661.2, 2.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "MRI", "start": 8, "end": 11, "id": 4}, {"text": "findings", "start": 12, "end": 20, "id": 5}, {"text": "of", "start": 21, "end": 23, "id": 6}, {"text": "the", "start": 24, "end": 27, "id": 7}, {"text": "mass", "start": 28, "end": 32, "id": 8}, {"text": ".", "start": 32, "end": 33, "id": 9}, {"text": "The", "start": 34, "end": 37, "id": 10}, {"text": "gadolinium", "start": 38, "end": 48, "id": 11}, {"text": "-", "start": 48, "end": 49, "id": 12}, {"text": "enhanced", "start": 49, "end": 57, "id": 13}, {"text": "T1", "start": 58, "end": 60, "id": 14}, {"text": "weighted", "start": 61, "end": 69, "id": 15}, {"text": "images", "start": 70, "end": 76, "id": 16}, {"text": "showed", "start": 77, "end": 83, "id": 17}, {"text": "a", "start": 84, "end": 85, "id": 18}, {"text": "posterior", "start": 86, "end": 95, "id": 19}, {"text": "pharyngeal", "start": 96, "end": 106, "id": 20}, {"text": "wall", "start": 107, "end": 111, "id": 21}, {"text": "mass", "start": 112, "end": 116, "id": 22}, {"text": "with", "start": 117, "end": 121, "id": 23}, {"text": "central", "start": 122, "end": 129, "id": 24}, {"text": "enhancement", "start": 130, "end": 141, "id": 25}, {"text": "and", "start": 142, "end": 145, "id": 26}, {"text": "hypointense", "start": 146, "end": 157, "id": 27}, {"text": "portions", "start": 158, "end": 166, "id": 28}, {"text": "(", "start": 167, "end": 168, "id": 29}, {"text": "arrows", "start": 168, "end": 174, "id": 30}, {"text": ")", "start": 174, "end": 175, "id": 31}, {"text": ".", "start": 175, "end": 176, "id": 32}]}
{"pdf_hash": "7e67e4f61628eef718c3350c25d70277ee40eedc", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Transesophageal echocardiography images of a 25dayold boy with complete transposition of the great arteries and multiple muscular ventricular septal defects. The guide wire (A) and sheath (B) were passed through the ventricular septal defect perventricularly from the right ventricle to left venticle. A leftsided disc (aortic disc) was deployed (C) and pulled back to the septum (D) and a rightsided disc (pulmonic end) was configured (E). A minimal residual shunt was observed on color Doppler ultrasonography (F). 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{"pdf_hash": "129b21a62b28bc3c44226a94b3ce45077c6bde06", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Two transverse postmortem ultrasound images of the chest in the same 23-week gestational-aged foetus, obtained 4 days after death. Postmortem ultrasound performed outside the water bath (a) and with foetus in the water bath (b). Notice how the thoracic cage was collapsed both due to body laxity and transducer compression in image (a), but how there is improved visualisation of the heart (asterisk) and lungs (white arrows) using the water bath (b) as the chest expands", "width": 652, "height": 760, "subcaptions": {"a": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "b": [26, 27, 28, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96]}, "subfigures": [{"id": "359a1dec-d8fe-482f-b700-a1c89d4eef20", "label": "a", "points": [[27.3, 20.3], [27.3, 272.6], [623.7, 272.6], [623.7, 20.3]], "color": "yellow"}, {"id": "f65ae92f-0537-4ce3-a567-af10c2d3db3f", "label": "b", "points": [[28.3, 297.3], [28.3, 727.9], [621.6, 727.9], [621.6, 297.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, 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{"pdf_hash": "7a937559faaedc55dc9f4e2a2f01bacaf534997c", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4. a\u2013c. Acquired SOV pseudoaneurysm (white arrow) in a 67-year-old man following aortic valve replacement. Axial (a, b) and oblique sagittal reconstructed (c) images from contrast-enhanced ECG-gated chest CT show contained rupture of left coronary sinus of Valsalva (Lt CS) with pseudoaneurysm formation (c, white asterisk) into the aortomitral space (black asterisk) with mass effect on the left atrium (LA) posteriorly and left main coronary artery (LMCA) anteriorly due to external compression (AA, ascending aorta; LV, left ventricle; RA, right atrium).", "width": 1418, "height": 474, "subcaptions": {"a": [25, 26, 27, 30, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 118], "b": [25, 26, 29, 30, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 70, 71, 72, 73, 78, 79, 80, 81, 82, 83, 84, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101], "c": [32, 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{"pdf_hash": "9826881ddd538b0627bada368043dd8f62d76ac7", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3 Immunolocalisation of aquaporin 1 (AQP1) expression in intra- and interlobular ducts of human pancreas (A\u2013H) and rat pancreas (I\u2013J). (A, B) Immunoperoxidase labelling of apical and basolateral membranes of intralobular ducts (id) in longitudinal (A) and transverse (B) section. Intralobular ducts are larger than intercalated ducts and have a clear luminal space surrounded by 8\u201314 small cuboidal cells when viewed in cross section. Note the absence of labelling from the islets of Langerhans (L) in (B). (C\u2013E) Immunofluorescence labelling of intralobular ducts (id) with antibodies to AQP1 (C) and cystic fibrosis transmembrane conductance regulator (CFTR) (D), and superimposed (E). While AQP1 labelling is uniform over the apical and basolateral surfaces (C), CFTR labelling at the apical membrane is patchy (arrowheads, D). Intercalated duct cells (ic) also show colocalisation of AQP1 and CFTR (arrows, D) at the apical membrane. (F\u2013H) Immunoperoxidase labelling of AQP1 in interlobular and main ducts. Labelling is mainly at the apical membrane in small interlobular ducts (arrows, F) and virtually absent from the larger interlobular ducts (G) and main duct (md, H). Note the strong labelling of capillaries (c, G) and centroacinar cells (ca, H) which provide a positive internal control. (I, J) Immunoperoxidase labelling of AQP1 in rat pancreas. Within the lobules (I), labelling was present in capillaries (c), venules (v), and intralobular ducts (ID). 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{"pdf_hash": "aeb8282247874db332b588d0e5d2e5890b7a22d6", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "FIGURE 7. Ultrasound energy plus targeting augment lipophilic delivery to C32 melanoma cells. Fluorescent lipid transferred from nanoparticles is green. (a) Confocal micrographs under normal conditions for nontargeted (NT) cells show minimal nonspecific internalization (dashed line indicates cell boundary). (b) a v b 3 integrin targeted (T) cells demonstrate specific targeting of nanoparticles to cell surface (green dots) and delivery of lipids in cell cytoplasm (diffuse green). (c) and (d) After ultrasound (US) insonification for 5 min, marked enhancement of cytoplasmic lipid delivery (diffuse green) was observed for both nontargeted (c) and targeted (d) cells, with the most dramatic effect for the targeted nanoparticles with insonification (d). The cell components observed are the nucleus (dark circular region) cell cytoplasm (bright interior), and cell membrane (bright borders). Scale bar: 2 mm. 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{"pdf_hash": "ed0815cf2ecdbb1fc6184af08f326b7341c7047c", "fig_key": "Figure5", "fig_uri": "10-Figure5-1.png", "text": "FIGURE 5 | Pectin immunogold labeling with LM5 (A\u2013C), LM6 (D\u2013F), JIM7 (G\u2013I) and LM5 antibodies (J\u2013L) in the cytoplasm and coat of pollen-like structures (left column) and embryogenic microspores (central column), and in inner cell walls of embryogenic microspores (right column). ct: cytoplasm; cw: cell wall; ex: exine; gs: Golgi stack; in: intine; s: starch granule; sl; subintinal layer; v: vacuole. 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{"pdf_hash": "102e6e6aeadbaa6b097e7ec6c93d883432b41d45", "fig_key": "Figure10", "fig_uri": "10-Figure10-1.png", "text": "Fig. 10. Semi-thin sections, 2 lm thickness, from an inner ear embedded in Spurr\u2019s resin after immunolabeling and clearing in MSBB. A typical transverse section through the organ of Corti stained by Richardson\u2019s stain at 20 (A) and 63 (C) with DIC optics. An adjacent section viewed by epi-fluorescence at 20 (B) and at 63 (D) displays high levels of non-specific fluorescence in the spiral limbus (SpL), tectorial membrane (TM), spiral ligament (SpLig), basilar membrane (BM) and Reissner\u2019s membrane (R) as well as within the epoxy. Hair cells and nerves are labeled for parvalbumin (green) and for DNA by To-Pro-3 (red). 129/CBA mouse, P6 months. 20 /.75 Plan-Apochromat objective lens (A\u2013B), 63 /1.4 oil immersion Plan-Apochromat (C\u2013D).", "width": 962, "height": 292, "subcaptions": {"a": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 53, 54, 55, 56], "b": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "c": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 49, 50, 51, 52, 53, 54, 55, 56], "d": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 57, 58, 59, 60, 61, 62, 63, 64, 71, 72, 73, 74, 75, 76, 77, 78, 79, 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{"pdf_hash": "6bb5ecc5fb80bdc015be187ec32b8a49e02620f5", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Magnetic resonance T,-weighted images showing the deleterious effects of a large dose of ethanol on ischemic brain injury. The brains of three different MCAO rats are shown [(A) vehicle control, (B) 2 g/kg ethanol, and (C) 3 g/kg ethanol given ip 1 hr before left MCAO]. (Left to right) Posterior to anterior coronal slices of the same animal. Note the larger lesion (whiter area) in the right hemisphere of rat brain (C). 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{"pdf_hash": "6c52752590ceced839dbf2080049677398db237e", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Fig. 6. (A-I) Duplication of the FAZ is unaffected by depletion of TbCentrin4. Control (A,B), TbCentrin4-RNAi (C-G) and TbCentrin2-RNAi (H,I) cells were fixed and labeled for FAZ (L3B2; red) and DNA (DAPI; blue). Note that the new FAZ (indicated by triple arrows) in control cells that undergo nuclear division remained attached to the cell body and that cell division initiated only after full segregation of the duplicated nuclei (distance ~6 \u03bcm ; not shown) (see also Robinson et al.,1995). In cells depleted of TbCentrin4 (C,D), the FAZ was the same length in both the 1K1N (control) and 1K0N (zoid) cells (E; n=100, mean \u00b1 s.d.). However, cell division initiated even before full segregation of the nuclei (F,G). By contrast, in cells depleted of TbCentrin2, formation of the new FAZ was inhibited (truncated new FAZ indicated by arrow), consistent with the known inhibition of cytokinesis (H,I). 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{"pdf_hash": "763851c4dbd858e515afcca0b3673a5114bffa62", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Transverse T2-weighted (3800 ms for TR, 90 ms for TE; A, B, C, D) and T1-weighted (540 ms for TR, 26 ms for TE; E, F, G, H) images of a dog with hepatic encephalopathy. Left images show the same level as right images. (A, B, C, D) Diffuse bilateral symmetrical hyperintense signals are demonstrated in the cerebral cortex from the parietal lobe to the temporal lobe (arrows) on the T2-weighted images. (E, F, G, H) No signal changes are visible on the T1-weighted images. 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{"pdf_hash": "e61f159558b369cb9970f8e72c0d0e10c3318b85", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Axial computed tomography (CT) scans of the patient before sunitinib induction therapy, demonstrating the primary renal tumour(*), pleural carcinomitosis of the lung (A) and liver (C) compared to the scans after 18 months of a standard sunitinib dose of 50 mg/day (4 weeks on, 2 weeks off) demonstrating virtual resolution of the lung (B) and liver (D) metastases. A: Axial CT-Scan before sunitinib induction therapy demonstrating pleural carcinomitosis of the lung; B: Axial CT-Scan after 18 months of standard sunitinib demonstrating virtual resolution of the pleural carcinomitosis of the lung; C: Axial CT-Scan before sunitinib induction demonstrating liver and retroperitoneal metastases; D: Axial CT-Scan after 18 months of standard sunitinib and a cytoreductive nephrectomy demonstrating virtual resolution of the liver metastases and removal of the primary tumour.", "width": 464, "height": 592, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98], "c": [128, 129, 130, 131, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 132, 133, 134, 37, 38, 39, 40, 135, 136, 123, 124, 125, 126, 127], "d": [163, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 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{"pdf_hash": "79e568c84d0c1c36bca41bad8e5a488be9bd8d54", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Representative CT images of patient 1 and patient 2 (patient 1: A\u2013B; patient 2: C\u2013D) showing compression fracture before and after radiation therapy. Twentyfive months after the completion of radiation therapy, patient 1 showed a wedge compression in L2 (B), where the radiation dose was the highest (30.9 Gy). 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{"pdf_hash": "3a34effdc8a95eb3548c67d01f9cc2ad106eae20", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1 Case 3 with SBT-MP. 25-year-old woman with bilateral ovarian SBT-MP. Sagittal T2WI (a) shows a solid mass (arrowhead) with inhomogeneous slight hyperintensity on the surface of a normal left ovarian structure (white arrow). The contralateral mass showed similar findings of normal ovarian structure within the mass (not shown). A small amount of ascites is present (black arrow). The internal branching architecture within both masses (arrows) is obscure on both sagittal and axial T2WI (b). Both ovarian masses are hyperintense on DWI (c). A photomicrograph (d) shows diffuse proliferation of the tumor cells in micropapillary projections with little stroma. Pinkish-stained hyaline degeneration (arrowheads) and randomly distributed edema (arrows) in the internal branching fibrous stalk are observed. 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{"pdf_hash": "15317d00afa75b88fe8b4e84ea5f0d40e44bba65", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. (A, B) Influence of TNF-a on actin cytoskeleton reorganization in HPMCs. (A) The fluorescence picture shows a predominant localization of F-actin at the rim of the cells (arrows) in absence of TNF-a. (B) The presence of TNF-a leads to reorganization of the actin cytoskeleton accompanied by the formation of actin stress fibers (arrowheads). Scale bars: 50 mm. (C, D) Spatial separation of HPMCs results in complete inhibition of NT formation. (C) Scanning electron and live-cell fluorescence microscopy pictures of HPMCs one hour after plating on homogeneously collagen I coated glass cover slides. The white arrows point to NTs spanned between the cells. Scale bars (left): 100 mm; (right): 20 mm. (D) HPMCs seeded on IKVAV functionalized (50 mM) microstructured surfaces with a gold disk diameter and spacing of 50 mm. Scanning electron microscopy (left panel) and livecell imaging analyses (right panel) were performed one hour after plating. Note that cells exclusively attach to the biofunctionalized gold disk structures. The inserts in A, B and D represent higher magnified images. 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{"pdf_hash": "f9e23427366bfe7e0e48015c32bc5432afe6b46d", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5 Contributions of hyoid-stream neural crest to adult cranial cartilages (continued). GFP-labeled cells are present in the ventral portion of the septum nasi (A; Sept nasi), in the oblique cartilage (C; Obl cart), and in the planum terminale (E; Pl term). (A) frontal section; anterior at top. (B\u2013E) transverse sections; images paired as in Fig. 2. Fluorescently labeled cartilage cells were only observed on the right side in each specimen. 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{"pdf_hash": "b0175ffab439fc8704bcc0b23755e0405042dcef", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Fig. 4 MIBI SPECT/CT and FCH PET/CT images of a 68-yold female patient with PHPT, an inconclusive cervical ultrasound report (dubious right inferior focus only visible on one plane) and a negative MIBI SPECT/CT. (a) MIBI SPECT maximumintensity-projection, (c) MIBI SPECT/CT transverse slice, (b) FCH PET maximum-intensityprojection, and (d) FCH PET/CT transverse slice. The MIBI and FCH MIP images (a, b) did not show clear focal uptake in the lower neck. However, the FCH PET/CT transverse slice (d) showed increased FCH uptake in a small ectopic deep-laying leftsided PTA in the upper mediastinum, which was negative on MIBI SPECT/CT (c) (red arrows). 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{"pdf_hash": "2f293c11dc7c0b4453dea0271e37e47e3013dac1", "fig_key": "Figure6", "fig_uri": "10-Figure6-1.png", "text": "Figure 6 . Localization of initial precipitation of apatitic mineral in experimental bioprosthetic valve calcification, visualized by transmission electron microscopy with electron energy loss spectroscopy (EELS). Elemental maps (phosphorus [blue] and calcium [yellow]) of glutaraldehydepretreated porcine aortic valve, produced using the Zeiss EM 902; (A) and (B) unimplanted tissue; (C) and (D) tissue implanted subdermally in the rat for 24 h; and (E) and (F) tissue implanted for 48 h. A single cell is shown in each set of photographs. Phosphorus but not calcium can be demonstrated in the unimplanted tissue (A and B), primarily in the nucleus (n) and focally in the cell membrane (arrow). Following 24 h implantation (C) and (D), there is accumulation of calcium diffusely in the extracellular space (asterisks). Following 48 h implantation (E) and (F), there is accumulation of calcium in association with the localized phosphorus, to form electrondense, well-defined precipitates (arrows). (e = 150 eV for contrast enhancement of unstained 30-nm sections. Specific energies: calcium e = 320-360 eV [L2,3 = 346.41, phosphorus e = 110-140 eV [L2,3 = 132.21. Original magnification 10,000 X. (Reproduced by permission from C. L. Webb et al., \u201cInhibition of mineralization of glutaraldehyde-pretreated bovine pericardium by A1C13 and other metallic salts in rat subdermal model studies,\u201d Am. J. 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{"pdf_hash": "b68e42fa71ce047c188f5e6c534209000349ef3f", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Assessment methods for total cross-sectional area and linear area. (A) Total cross-sectional area at the third lumber vertebra analysed using research software. (B) Linear measures applied to the right and left psoas and paraspinal groups using the digital ruler in radiological software. (A) Assessed total L3 cross-sectional area using Slice-O-Matic research software. (B) Applied the eight linear measures to the L3 using the digital ruler native to most radiological software. To minimize the inconsistencies between analysts, the orientation of each line remained in the horizontal or vertical direction as the scan appears on the screen, irrespective of the orientation of the patients (i.e. on some scans, the individuals did not appear evenly flat on their backs). A strategy to envision the linear measurement is to consider the line placement not as lines drawn such that their length and width is perfectly within the boundaries of the muscle itself, but rather to draw two lines within which the entirety of the muscle would be enclosed if they were to form a rectangular box, as indicated with dotted guideline on Figure 1B. A detailed step-by-step protocol is included in Supporting Information to the original Avrutin et al. publication that established this method.", "width": 1346, "height": 540, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94]}, "subfigures": [{"id": "1facf451-39ca-472b-9702-49cf494cfb4b", "label": "a", "points": [[4.9, 23.1], [4.9, 533.4], [668.3, 533.4], [668.3, 23.1]], "color": "yellow"}, {"id": "a25aec4b-f219-49b4-bbc7-83f1505128d3", "label": "b", "points": [[687.4, 33.7], [687.4, 537.7], [1325.3, 537.7], [1325.3, 33.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Assessment", "start": 9, 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{"pdf_hash": "72ab4fa140f4152bc2a853bfd66c8b2145d7d61b", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Anatomically standardized BF-227 PET images and the results of eZIS with or without the removal of the skull uptake (\"scalping\"). Shown are the data of Case 2, a 66-year-old ND woman. (a-c) An anatomically standardized image of the original BF-227 PET image (a) and the results of eZIS (b, c). (a) The white line represents the contour of the standard brain. Some portions of the skull uptake are seen in the white line (arrows). (b) A high Z-score area is observed at the peripheral region of the brain (arrowheads). (c) The abnormalities are seen globally on the surface map (arrows). (d-f) An anatomically standardized image after \"scalping\" (d) and the results of eZIS (e, f). (d) The edge of the brain matches the white line. 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{"pdf_hash": "98d8c22db940bb236bcc143d1e13ae25c9e4b4e4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Dynamic (A, C, D) and plain (B) computed tomography of the abdomen. The size of the hematoma is 110 mm \u00c2 32 mm, 73 mm \u00c2 44 mm, 73 mm \u00c2 61 mm, and 45 mm \u00c2 34 mm at Days (A) 11, (B) 18, (C) 25, and (D) 65 after the endoscopic mucosal resection.", "width": 1274, "height": 864, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10], "b": [12, 13, 14, 15]}, "subfigures": [{"id": "7ff16e18-2eef-4cf1-add6-614e2f85416c", "label": "a", "points": [[49.4, 25.8], [49.4, 430.4], [639.1, 430.4], [639.1, 25.8]], "color": "yellow"}, {"id": "aad1c221-67aa-4ca5-95f3-c07675c06305", "label": "b", "points": [[47.4, 438.4], [47.4, 830.9], [647.1, 830.9], [647.1, 438.4]], "color": "cyan"}, {"id": "5f6ea218-adf6-49c9-8fbe-fb9716f6ca7e", "label": "a", "points": [[667.2, 25.8], [667.2, 406.2], [1232.8, 406.2], [1232.8, 25.8]], "color": "magenta"}, {"id": "106dd95e-ffb5-4e0a-8343-644b8a732d38", "label": "a", "points": [[665.2, 418.3], [665.2, 834.9], [1230.8, 834.9], [1230.8, 418.3]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 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{"pdf_hash": "e91ddb6286b4892a7b7cc957e7457dd05604a029", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "FIGURE 3. (A) SPECT in vivo time-activity curves of 111 In activity, decay-corrected and fit to monoexponential function, for epicardial and endocardial endothelial progenitor cell injections, from which half-life of cell clearance was calculated. Epicardial injections had clearance half-life of 69 6 26 h, and endocardial injections had clearance half-life of 60 6 21 h. Symbols represent normalized raw data. Representative images are shown (B-E) of SPECT scans acquired with increasing acquisition time. 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{"pdf_hash": "2df4b256bd3f963970f13528a39ba686df299943", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Sagittal MR images of the ankle joint", "width": 1300, "height": 652, "subcaptions": null, "subfigures": [{"id": "581de4ae-74b7-47cd-b27c-ddbd456e5a1e", "label": "a", "points": [[38.8, 51.8], [38.8, 647.4], [646.7, 647.4], [646.7, 51.8]], "color": "yellow"}, {"id": "c49b8e5f-0774-4bb7-9ead-6c7a92bb152f", "label": "b", "points": [[1295.7, 60], [1295.7, 647.4], [687.8, 647.4], [687.8, 60]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Sagittal", "start": 10, "end": 18, "id": 3}, {"text": "MR", "start": 19, "end": 21, "id": 4}, {"text": "images", "start": 22, "end": 28, "id": 5}, {"text": "of", "start": 29, "end": 31, "id": 6}, {"text": "the", "start": 32, "end": 35, "id": 7}, {"text": "ankle", "start": 36, "end": 41, "id": 8}, {"text": "joint", "start": 42, "end": 47, "id": 9}]}
{"pdf_hash": "948ef617fda4bdffeda0d2fed5f32c3cc67af18a", "fig_key": "Figure21", "fig_uri": "13-Figure21-1.png", "text": "Fig. 21. Lymphobronchial TB. Progressive stages of the effects on the lung shown on contrast-enhanced CT (in different patients) from earliest (A) to latest (E). (A) Lymphadenopathy is seen involving the right hilum (arrowhead) and, unlike on the left, the right bronchus is not visible (it is compressed). (B) Distal to a right-sided compression, there is air-space disease. Posteriorly in the parenchyma there are air bronchograms and visible vessels. Anteriorly (the right middle lobe) the bronchi are filled with fluid (wet lung) (arrowhead). The lung enhances throughout. (C) Distal to the bronchus intermedius compression (by hilar and subcarinal lymphadenopathy) the right middle lobe shows nonenhancement, lack of visible bronchi, and a bulging margin (arrowheads) indicating a necrotic lung lobe that is expansile. (D) The right middle lobe necrosis shows early breakdown with air pockets (arrowhead). In contrast, the left lower lobe shows air-space disease with air bronchograms and enhancing parenchyma (in keeping with viability). (E) Advanced cavitation (air-filled areas) in multiple locations within the right lung, which also shows some areas of necrosis (low density, nonenhancing) and some areas of viable consolidated lung (enhancing with air bronchograms). (Parts (C), (D) and (E) from Andronikou S, Wieselthaler N. Imaging for tuberculosis in children. In: Schaaf HS, Zumla A, editors. Tuberculosis: a comprehensive clinical reference. Philadelphia: Saunders Elsevier; 2009. p. 270; with permission.)", "width": 1050, "height": 1238, "subcaptions": {"a": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68], "b": [69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124], "c": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 125, 126, 127], "d": [169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211], "e": [256, 257, 212, 213, 214, 215, 216, 217, 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{"pdf_hash": "d4eb5439719d93bbcb7b4e97b9afaa3797d64ea2", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "Fig. 7. Light microscopic histology of pup brains. (a), (b) Coronal brain sections from a 2 year old normal dog (a) and a 2 year old shaking pup (b). The mutant brain appears to lack any myelin except some pale staining of parts of the sub-cortical white matter and internal capsule. Higher power images of the internal capsule in a 4 week old normal dog and 5 week old sh pup (c, d) and a normal dog at 1 1/2 years (e) and shaking pup at 4 months (f) demonstrate normal myelination in wild type (c, e) but a marked paucity of myelin in the mutant (d, f). At 5 weeks in the sh pup (d) there are only one or two short stretches of myelin (arrows) whereas at 4 months there are scattered myelin sheaths throughout the neuropil (f) but much less than the normal dog at both time points (c, e). An increase in axon size in the older normal dog (e) compared to the younger dog (c) is evident. (a),(b); Weil stain, 40 \u03bcm thick sections bar = 1 cm, (c)-(f); One micron Toluidine blue stained sections bar = 20 \u03bcm.", "width": 950, "height": 1084, "subcaptions": {"a": [11, 12, 13, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [15, 16, 17, 18, 19, 20, 21, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "c": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 91, 112, 113, 114, 115, 116, 117, 118, 119, 122, 137, 138, 139, 140, 141, 142, 143, 144, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216], "d": [128, 129, 130, 131, 132, 133, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 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{"pdf_hash": "675d5727ef7e484a6f739bf099500f23d3822bec", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "Fig 6. Fluorescein angiography (FA) images and color maps of retinal thickness using optical coherence tomography (OCT) images. (A, C) FA images of eyes with nonperfusion areas (NPAs) (shown in orange). (B, D) Color maps of eyes with NPAs which corresponded to the thinning areas (in blue) detected by OCT. (E) FA of eyes without NPAs. 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{"pdf_hash": "968809599390b52a06c010190f61a9c07d0d44bc", "fig_key": "Figure2", "fig_uri": "1-Figure2-1.png", "text": "Figure 2 MRI dorsal spine axial images showing ring enhancing intramedullary lesion s/o tuberculoma (T1+C (A), arrow) and arachnoiditis with cord compression (T1-weighted image (B), T1+C (C)).", "width": 934, "height": 380, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "7fcac30f-e187-4f5e-86e3-33bc72e8c727", "label": "a", "points": [[2.3, 1.2], [2.3, 378.9], [321, 378.9], [321, 1.2]], "color": "yellow"}, {"id": "d5ea7247-b097-4c6f-8a42-9e666ed0d1e4", "label": "b", "points": [[334.2, 2.7], [334.2, 374.5], [623.4, 374.5], [623.4, 2.7]], "color": "cyan"}, {"id": "bd305326-f38f-4293-966c-269b7c6d118f", "label": "b", "points": [[638.2, 2.7], [638.2, 377.5], [928.8, 377.5], [928.8, 2.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "MRI", "start": 9, "end": 12, "id": 2}, {"text": "dorsal", "start": 13, "end": 19, "id": 3}, {"text": "spine", "start": 20, "end": 25, "id": 4}, {"text": "axial", "start": 26, "end": 31, "id": 5}, {"text": "images", "start": 32, "end": 38, "id": 6}, {"text": "showing", "start": 39, "end": 46, "id": 7}, {"text": "ring", "start": 47, "end": 51, "id": 8}, {"text": "enhancing", "start": 52, "end": 61, "id": 9}, {"text": "intramedullary", "start": 62, "end": 76, "id": 10}, {"text": "lesion", "start": 77, "end": 83, "id": 11}, {"text": "s", "start": 84, "end": 85, "id": 12}, {"text": "/", "start": 85, "end": 86, "id": 13}, {"text": "o", "start": 86, "end": 87, "id": 14}, {"text": "tuberculoma", "start": 88, "end": 99, "id": 15}, {"text": "(", "start": 100, "end": 101, "id": 16}, {"text": "T1+C", "start": 101, "end": 105, "id": 17}, {"text": "(", "start": 106, "end": 107, "id": 18}, {"text": "A", "start": 107, "end": 108, "id": 19}, {"text": ")", "start": 108, "end": 109, "id": 20}, {"text": ",", "start": 109, "end": 110, "id": 21}, {"text": "arrow", "start": 111, "end": 116, "id": 22}, {"text": ")", "start": 116, "end": 117, "id": 23}, {"text": "and", "start": 118, "end": 121, "id": 24}, {"text": "arachnoiditis", "start": 122, "end": 135, "id": 25}, {"text": "with", "start": 136, "end": 140, "id": 26}, {"text": "cord", "start": 141, "end": 145, "id": 27}, {"text": "compression", "start": 146, "end": 157, "id": 28}, {"text": "(", "start": 158, "end": 159, "id": 29}, {"text": "T1-weighted", "start": 159, "end": 170, "id": 30}, {"text": "image", "start": 171, "end": 176, "id": 31}, {"text": "(", "start": 177, "end": 178, "id": 32}, {"text": "B", "start": 178, "end": 179, "id": 33}, {"text": ")", "start": 179, "end": 180, "id": 34}, {"text": ",", "start": 180, "end": 181, "id": 35}, {"text": "T1+C", "start": 182, "end": 186, "id": 36}, {"text": "(", "start": 187, "end": 188, "id": 37}, {"text": "C", "start": 188, "end": 189, "id": 38}, {"text": ")", "start": 189, "end": 190, "id": 39}, {"text": ")", "start": 190, "end": 191, "id": 40}, {"text": ".", "start": 191, "end": 192, "id": 41}]}
{"pdf_hash": "088b500998f20fed0e51a5a93d9f193db26a1801", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 MRI Sagittal T1-post contrast (left) and Axial T2 (right) demonstrating a diffusely infiltrative brainstem lesion", "width": 1354, "height": 616, "subcaptions": {"a": [4, 5, 6, 7, 8, 9], "b": [11, 12, 13, 14, 15]}, "subfigures": [{"id": "ec5c2ac3-bd96-4e70-af19-74c956637edb", "label": "a", "points": [[4.3, 4.3], [4.3, 609.6], [759.4, 609.6], [759.4, 4.3]], "color": "yellow"}, {"id": "c2506ed3-cefe-4c50-9145-df2590526469", "label": "b", "points": [[770.1, 611.8], [770.1, 8.6], [1349.8, 8.6], [1349.8, 611.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "MRI", "start": 7, "end": 10, "id": 3}, {"text": "Sagittal", "start": 11, "end": 19, "id": 4}, {"text": "T1-post", "start": 20, "end": 27, "id": 5}, {"text": "contrast", "start": 28, "end": 36, "id": 6}, {"text": "(", "start": 37, "end": 38, "id": 7}, {"text": "left", "start": 38, "end": 42, "id": 8}, {"text": ")", "start": 42, "end": 43, "id": 9}, {"text": "and", "start": 44, "end": 47, "id": 10}, {"text": "Axial", "start": 48, "end": 53, "id": 11}, {"text": "T2", "start": 54, "end": 56, "id": 12}, {"text": "(", "start": 57, "end": 58, "id": 13}, {"text": "right", "start": 58, "end": 63, "id": 14}, {"text": ")", "start": 63, "end": 64, "id": 15}, {"text": "demonstrating", "start": 65, "end": 78, "id": 16}, {"text": "a", "start": 79, "end": 80, "id": 17}, {"text": "diffusely", "start": 81, "end": 90, "id": 18}, {"text": "infiltrative", "start": 91, "end": 103, "id": 19}, {"text": "brainstem", "start": 104, "end": 113, "id": 20}, {"text": "lesion", "start": 114, "end": 120, "id": 21}]}
{"pdf_hash": "447d10bb03b1778b76cd7b87609d790e18076a48", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "FIG. 1. A 69-year-old man with a category IIF cystic lesion in the right kidney. (A) Initial contrast-enhanced transverse computed tomography scan depicts a 2.8-cm cystic mass that contains multiple minimally smooth thickening of septa. (B) On follow-up 9 months later, the cystic renal mass contains grossly thickened and irregular septa in which there is measurable enhancement (white arrow). On the basis of these findings, the lesion was reclassified as a category III cyst. 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{"pdf_hash": "daeabf2777fe86315d87ddb1fa2e0527fc157a62", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Anatomical sub-regions of the corpus callosum and cortical regions it projects to according to Witelson (1989). Subdivisions of the corpus callosum in seven regions after tracing and parcellating in AnalyzeDirect, Inc., KS: SP splenium (projects to occipital, inferior temporal cortex), IS isthmus (projects to superior temporal, posterior parietal cortex), PM posterior midbody (projects to somatosensory, posterior, parietal cortex), AM anterior midbody (projects to motor cortex), RB rostral body (projects to premotor, supplementary motor cortex), G genu (projects to prefrontal cortex), R rostrum (projects to caudal/orbital prefrontal, inferior premotor cortex). Upper figure shows manually traced outline, projected for illustration onto a representative brain image in coronal section. 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{"pdf_hash": "b2d3c4a0c75ea4cc90ddefafe031abd17f6831af", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Case 1. A 47-year-old female with anaplastic oligodendroglioma. Preoperative axial (A) and coronal (B) T 1 -weighted with gadolinium, axial T 2 -weighted (C), and axial diffusionweighted (D) magnetic resonance images showing an enhanced and highly cellular infi ltrative tumor in the left insula and fronto-parietal operculum.", "width": 666, "height": 682, "subcaptions": {"a": [16, 17, 18, 19, 25, 26, 27, 28, 29], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29], "c": [32, 33, 34, 35, 36, 37, 31], "d": [40, 41, 42, 43, 44]}, "subfigures": [{"id": "ce0094d4-05cc-4a38-a2ce-207737be5e0a", "label": "a", "points": [[2.4, 0.9], [2.4, 317.6], [311.7, 317.6], [311.7, 0.9]], "color": "yellow"}, {"id": "6fb8ac0f-90b1-4168-95ab-f5d3768a1d64", "label": "b", "points": [[317, 2], [317, 316.5], [651.5, 316.5], [651.5, 2]], "color": "cyan"}, {"id": "57d94308-d7e7-4de0-8c4e-0264fd20e5ed", "label": "c", "points": [[8.7, 326], [8.7, 632.2], [311.7, 632.2], [311.7, 326]], "color": "magenta"}, {"id": "f966f312-fc2a-497f-8abb-48ce4c165fe7", "label": "d", "points": [[323.3, 332.3], [323.3, 639.5], [665.2, 639.5], [665.2, 332.3]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Case", "start": 7, "end": 11, "id": 3}, {"text": "1", "start": 12, "end": 13, "id": 4}, {"text": ".", "start": 13, "end": 14, "id": 5}, {"text": "A", "start": 15, "end": 16, "id": 6}, {"text": "47-year", "start": 17, "end": 24, "id": 7}, {"text": "-", "start": 24, "end": 25, "id": 8}, {"text": "old", "start": 25, "end": 28, "id": 9}, {"text": "female", "start": 29, "end": 35, "id": 10}, {"text": "with", "start": 36, "end": 40, "id": 11}, {"text": "anaplastic", "start": 41, "end": 51, "id": 12}, {"text": "oligodendroglioma", "start": 52, "end": 69, "id": 13}, {"text": ".", "start": 69, "end": 70, "id": 14}, {"text": "Preoperative", "start": 71, "end": 83, "id": 15}, {"text": "axial", "start": 84, "end": 89, "id": 16}, {"text": "(", "start": 90, "end": 91, "id": 17}, {"text": "A", "start": 91, "end": 92, "id": 18}, {"text": ")", "start": 92, "end": 93, "id": 19}, {"text": "and", "start": 94, "end": 97, "id": 20}, {"text": "coronal", "start": 98, "end": 105, "id": 21}, {"text": "(", "start": 106, "end": 107, "id": 22}, {"text": "B", "start": 107, "end": 108, "id": 23}, {"text": ")", "start": 108, "end": 109, "id": 24}, {"text": "T", "start": 110, "end": 111, "id": 25}, {"text": "1", "start": 112, "end": 113, "id": 26}, {"text": "-weighted", "start": 114, "end": 123, "id": 27}, {"text": "with", "start": 124, "end": 128, "id": 28}, {"text": "gadolinium", "start": 129, "end": 139, "id": 29}, {"text": ",", "start": 139, "end": 140, "id": 30}, {"text": "axial", "start": 141, "end": 146, "id": 31}, {"text": "T", "start": 147, "end": 148, "id": 32}, {"text": "2", "start": 149, "end": 150, "id": 33}, {"text": "-weighted", "start": 151, "end": 160, "id": 34}, {"text": "(", "start": 161, "end": 162, "id": 35}, {"text": "C", "start": 162, "end": 163, "id": 36}, {"text": ")", "start": 163, "end": 164, "id": 37}, {"text": ",", "start": 164, "end": 165, "id": 38}, {"text": "and", "start": 166, "end": 169, "id": 39}, {"text": "axial", "start": 170, "end": 175, "id": 40}, {"text": "diffusionweighted", "start": 176, "end": 193, "id": 41}, {"text": "(", "start": 194, "end": 195, "id": 42}, {"text": "D", "start": 195, "end": 196, "id": 43}, {"text": ")", "start": 196, "end": 197, "id": 44}, {"text": "magnetic", "start": 198, "end": 206, "id": 45}, {"text": "resonance", "start": 207, "end": 216, "id": 46}, {"text": "images", "start": 217, "end": 223, "id": 47}, {"text": "showing", "start": 224, "end": 231, "id": 48}, {"text": "an", "start": 232, "end": 234, "id": 49}, {"text": "enhanced", "start": 235, "end": 243, "id": 50}, {"text": "and", "start": 244, "end": 247, "id": 51}, {"text": "highly", "start": 248, "end": 254, "id": 52}, {"text": "cellular", "start": 255, "end": 263, "id": 53}, {"text": "infi", "start": 264, "end": 268, "id": 54}, {"text": "ltrative", "start": 269, "end": 277, "id": 55}, {"text": "tumor", "start": 278, "end": 283, "id": 56}, {"text": "in", "start": 284, "end": 286, "id": 57}, {"text": "the", "start": 287, "end": 290, "id": 58}, {"text": "left", "start": 291, "end": 295, "id": 59}, {"text": "insula", "start": 296, "end": 302, "id": 60}, {"text": "and", "start": 303, "end": 306, "id": 61}, {"text": "fronto", "start": 307, "end": 313, "id": 62}, {"text": "-", "start": 313, "end": 314, "id": 63}, {"text": "parietal", "start": 314, "end": 322, "id": 64}, {"text": "operculum", "start": 323, "end": 332, "id": 65}, {"text": ".", "start": 332, "end": 333, "id": 66}]}
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{"pdf_hash": "a107e4febb16f5ac97e362df15bc16557e11797e", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Contrast-enhanced 3-D CT images of a basilar artery aneurysm. CR (a) and conventional VR (b) depict the base of the skull with the circle of Willis, as well as the fusiform dilation of the basilar artery. Note the more natural representation of the bones and vessels in the CR image", "width": 866, "height": 432, "subcaptions": {"a": [16, 17, 18, 15], "b": [20, 21, 22, 23, 24]}, "subfigures": [{"id": "ffef58bc-2250-433e-829d-8a0a6d15dad4", "label": "a", "points": [[1.8, 1.2], [1.8, 425.3], [434.1, 425.3], [434.1, 1.2]], "color": "yellow"}, {"id": "fb297de3-e3da-49d3-8ac5-64dff2e2dde4", "label": "b", "points": [[438.2, 6.7], [438.2, 425.3], [865, 425.3], [865, 6.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Contrast", "start": 7, "end": 15, "id": 3}, {"text": "-", "start": 15, "end": 16, "id": 4}, {"text": "enhanced", "start": 16, "end": 24, "id": 5}, {"text": "3-D", "start": 25, "end": 28, "id": 6}, {"text": "CT", "start": 29, "end": 31, "id": 7}, {"text": "images", "start": 32, "end": 38, "id": 8}, {"text": "of", "start": 39, "end": 41, "id": 9}, {"text": "a", "start": 42, "end": 43, "id": 10}, {"text": "basilar", "start": 44, "end": 51, "id": 11}, {"text": "artery", "start": 52, "end": 58, "id": 12}, {"text": "aneurysm", "start": 59, "end": 67, "id": 13}, {"text": ".", "start": 67, "end": 68, "id": 14}, {"text": "CR", "start": 69, "end": 71, "id": 15}, {"text": "(", "start": 72, "end": 73, "id": 16}, {"text": "a", "start": 73, "end": 74, "id": 17}, {"text": ")", "start": 74, "end": 75, "id": 18}, {"text": "and", "start": 76, "end": 79, "id": 19}, {"text": "conventional", "start": 80, "end": 92, "id": 20}, {"text": "VR", "start": 93, "end": 95, "id": 21}, {"text": "(", "start": 96, "end": 97, "id": 22}, {"text": "b", "start": 97, "end": 98, "id": 23}, {"text": ")", "start": 98, "end": 99, "id": 24}, {"text": "depict", "start": 100, "end": 106, "id": 25}, {"text": "the", "start": 107, "end": 110, "id": 26}, {"text": "base", "start": 111, "end": 115, "id": 27}, {"text": "of", "start": 116, "end": 118, "id": 28}, {"text": "the", "start": 119, "end": 122, "id": 29}, {"text": "skull", "start": 123, "end": 128, "id": 30}, {"text": "with", "start": 129, "end": 133, "id": 31}, {"text": "the", "start": 134, "end": 137, "id": 32}, {"text": "circle", "start": 138, "end": 144, "id": 33}, {"text": "of", "start": 145, "end": 147, "id": 34}, {"text": "Willis", "start": 148, "end": 154, "id": 35}, {"text": ",", "start": 154, "end": 155, "id": 36}, {"text": "as", "start": 156, "end": 158, "id": 37}, {"text": "well", "start": 159, "end": 163, "id": 38}, {"text": "as", "start": 164, "end": 166, "id": 39}, {"text": "the", "start": 167, "end": 170, "id": 40}, {"text": "fusiform", "start": 171, "end": 179, "id": 41}, {"text": "dilation", "start": 180, "end": 188, "id": 42}, {"text": "of", "start": 189, "end": 191, "id": 43}, {"text": "the", "start": 192, "end": 195, "id": 44}, {"text": "basilar", "start": 196, "end": 203, "id": 45}, {"text": "artery", "start": 204, "end": 210, "id": 46}, {"text": ".", "start": 210, "end": 211, "id": 47}, {"text": "Note", "start": 212, "end": 216, "id": 48}, {"text": "the", "start": 217, "end": 220, "id": 49}, {"text": "more", "start": 221, "end": 225, "id": 50}, {"text": "natural", "start": 226, "end": 233, "id": 51}, {"text": "representation", "start": 234, "end": 248, "id": 52}, {"text": "of", "start": 249, "end": 251, "id": 53}, {"text": "the", "start": 252, "end": 255, "id": 54}, {"text": "bones", "start": 256, "end": 261, "id": 55}, {"text": "and", "start": 262, "end": 265, "id": 56}, {"text": "vessels", "start": 266, "end": 273, "id": 57}, {"text": "in", "start": 274, "end": 276, "id": 58}, {"text": "the", "start": 277, "end": 280, "id": 59}, {"text": "CR", "start": 281, "end": 283, "id": 60}, {"text": "image", "start": 284, "end": 289, "id": 61}]}
{"pdf_hash": "558a6962d1b8af67d7374914a78760f07d67346a", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 (A) Photomicrographs demonstrating a spindle cell tumour with interspersed hypocellular areas (Hematoxylin and Eosin stain, \u00d740 magnificaiton). (B) The spindle cells show moderate degree of nuclear pleomorphism (Hematoxylin and Eosin stain, \u00d7100 magnification). (C) Occasional bizarre tumour cells (Hematoxylin and Eosin stain, \u00d7200 magnificaiton). (D) An occasional mitotic figure was noted (Hematoxylin and Eosin stain, \u00d7400 magnificaiton).", "width": 652, "height": 514, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "c": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63], "d": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82]}, "subfigures": [{"id": "347ff0b4-7d5d-4bcf-926f-1159745616a1", "label": "a", "points": [[24, 19.4], [24, 252.2], [322.7, 252.2], [322.7, 19.4]], "color": "yellow"}, {"id": "3c1fa1ef-77eb-4936-a9a7-d715f5625ffc", "label": "b", "points": [[328.9, 20.5], [328.9, 252.2], [631.7, 252.2], [631.7, 20.5]], "color": "cyan"}, {"id": "da0f82f7-cb57-45f6-b21d-06dc44684e09", "label": "c", "points": [[20.9, 251.2], [20.9, 486], [333, 486], [333, 251.2]], "color": "magenta"}, {"id": 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{"pdf_hash": "366137f0ac6097ae9ee45793a343268fd3b31f74", "fig_key": "Figure3", "fig_uri": "16-Figure3-1.png", "text": "Figure 3. Sagittal (A) and coronal (B) views of the T map of control (n = 19) > schizophrenia (n = 18) functional connectivity of the left m/pCC seed, displayed at a threshold of p < .01. The Talairach \u00d7 coordinate of the displayed slice is shown in the right side of each image. White arrows point to the site within the dorsal anterior cingulate cortex showing significantly greater functional connectivity with the left m/pCC seed in the control subjects, in comparison to the patients.", "width": 790, "height": 318, "subcaptions": {"a": [3, 4, 5, 6], "b": [8, 9, 10, 11]}, "subfigures": [{"id": "092be6c8-5923-4dcc-a635-3f0e1923ce72", "label": "a", "points": [[0.7, 4.8], [0.7, 315.5], [421.2, 315.5], [421.2, 4.8]], "color": "yellow"}, {"id": "40f19d47-8ed6-45cc-a9f0-ad8378abdc52", "label": "b", "points": [[469.9, 1], [469.9, 315.5], [785.6, 315.5], [785.6, 1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Sagittal", "start": 10, "end": 18, "id": 3}, {"text": "(", "start": 19, "end": 20, "id": 4}, {"text": "A", "start": 20, "end": 21, "id": 5}, {"text": ")", "start": 21, "end": 22, "id": 6}, {"text": "and", "start": 23, "end": 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{"pdf_hash": "51baaa794ccbe6a26a08de4919258a0d97187b7f", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Fig 6. A Longitudinal scan of the nail: normal aspect. The nail plate (*) is as a flawless trilaminar structure with sharp borders. Under the nail plate the nail bed (^) appears as a ipo-isoechoic area under the nail plate and ending in the germinative matrix (#). The insertion and enthesis of the extensor tendon is next to the germinal matrix (\u00b0). A picture of a psoriatic nail is in B. The nail plate is altered, with loss of the trilaminar structure and thickening of the plate. The nail bed is thickened, with loss of homogeneity. In C the PD signal is depicted. Small vessels appear with a weak signal characterizing all the bed and some spots are also evident along the venule just next to the tendon. 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{"pdf_hash": "08e5d471d3d7af3492dadbeff2f39e3345b16d8c", "fig_key": "Figure4", "fig_uri": "10-Figure4-1.png", "text": "FIG. 4. Axial view of the reconstructed CBCT image under 5, 10, 20, and 40 x-ray projections are shown. The top row is obtained from our new algorithm, while the bottom one is from the FDK algorithm.", "width": 1058, "height": 510, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [4, 5, 6, 7, 8, 9, 10, 11, 14, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "c": [4, 5, 6, 7, 8, 9, 10, 11, 16, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "d": [4, 5, 6, 7, 8, 9, 10, 11, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "e": [4, 5, 6, 7, 8, 9, 10, 11, 12, 20, 21, 22, 23, 24, 25, 26, 38, 39, 40, 41, 42, 43, 44, 45, 46], "f": [4, 5, 6, 7, 8, 9, 10, 11, 14, 20, 21, 22, 23, 24, 25, 26, 38, 39, 40, 41, 42, 43, 44, 45, 46], "g": [4, 5, 6, 7, 8, 9, 10, 11, 16, 20, 21, 22, 23, 24, 25, 26, 38, 39, 40, 41, 42, 43, 44, 45, 46], "h": [4, 5, 6, 7, 8, 9, 10, 11, 19, 20, 21, 22, 23, 24, 25, 26, 38, 39, 40, 41, 42, 43, 44, 45, 46]}, "subfigures": [{"id": "4cc7f489-e99c-419a-8b3b-2a98fe2c4a05", "label": "a", "points": [[149.7, 1.4], [149.7, 202], [353.6, 202], [353.6, 1.4]], "color": "yellow"}, {"id": "c82c0546-44a7-485e-8002-c851c732bf06", "label": "b", "points": [[383.7, -0.3], [383.7, 202], [585.9, 202], [585.9, -0.3]], "color": "cyan"}, {"id": "96ade98c-6fca-41c6-b1a7-a480b24ef8f0", "label": "c", "points": [[626, 3.1], [626, 202], [821.6, 202], [821.6, 3.1]], "color": "magenta"}, {"id": "963dffa2-2374-4028-8da6-e14e5831862a", "label": "d", "points": [[856.7, 1.4], [856.7, 198.6], [1052.2, 198.6], [1052.2, 1.4]], "color": "springgreen"}, {"id": "8fc08e35-1fb6-4dc4-9861-b713de8b3922", "label": "e", "points": [[156.3, 213.7], [156.3, 415.9], [348.6, 415.9], [348.6, 213.7]], "color": "tomato"}, {"id": "8000bef6-dd11-4976-b9eb-3f113f60eb4c", "label": "f", "points": [[385.3, 210.3], [385.3, 415.9], [590.9, 415.9], [590.9, 210.3]], "color": "deepskyblue"}, {"id": "971fa358-f271-4617-943c-afb1892e722a", "label": "g", "points": [[823.2, 415.9], [823.2, 210.3], [621, 210.3], [621, 415.9]], "color": "orange"}, {"id": "0c89641e-120e-435a-bda3-63635cb50222", "label": "h", "points": [[858.3, 212], [858.3, 415.9], [1057.2, 415.9], [1057.2, 212]], "color": "hotpink"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Axial", "start": 8, "end": 13, "id": 4}, {"text": "view", "start": 14, "end": 18, "id": 5}, {"text": "of", "start": 19, "end": 21, "id": 6}, {"text": "the", "start": 22, "end": 25, "id": 7}, {"text": "reconstructed", "start": 26, "end": 39, "id": 8}, {"text": "CBCT", "start": 40, "end": 44, "id": 9}, {"text": "image", "start": 45, "end": 50, "id": 10}, {"text": "under", "start": 51, "end": 56, "id": 11}, {"text": "5", "start": 57, "end": 58, "id": 12}, {"text": ",", "start": 58, "end": 59, "id": 13}, {"text": "10", "start": 60, "end": 62, "id": 14}, {"text": ",", "start": 62, "end": 63, "id": 15}, {"text": "20", "start": 64, "end": 66, "id": 16}, {"text": ",", "start": 66, "end": 67, "id": 17}, {"text": "and", "start": 68, "end": 71, "id": 18}, {"text": "40", "start": 72, "end": 74, "id": 19}, {"text": "x", "start": 75, "end": 76, "id": 20}, {"text": "-", "start": 76, "end": 77, "id": 21}, {"text": "ray", "start": 77, "end": 80, "id": 22}, {"text": "projections", "start": 81, "end": 92, "id": 23}, {"text": "are", "start": 93, "end": 96, "id": 24}, {"text": "shown", "start": 97, "end": 102, "id": 25}, {"text": ".", "start": 102, "end": 103, "id": 26}, {"text": "The", "start": 104, "end": 107, "id": 27}, {"text": "top", "start": 108, "end": 111, "id": 28}, {"text": "row", "start": 112, "end": 115, "id": 29}, {"text": "is", "start": 116, "end": 118, "id": 30}, {"text": "obtained", "start": 119, "end": 127, "id": 31}, {"text": "from", "start": 128, "end": 132, "id": 32}, {"text": "our", "start": 133, "end": 136, "id": 33}, {"text": "new", "start": 137, "end": 140, "id": 34}, {"text": "algorithm", "start": 141, "end": 150, "id": 35}, {"text": ",", "start": 150, "end": 151, "id": 36}, {"text": "while", "start": 152, "end": 157, "id": 37}, {"text": "the", "start": 158, "end": 161, "id": 38}, {"text": "bottom", "start": 162, "end": 168, "id": 39}, {"text": "one", "start": 169, "end": 172, "id": 40}, {"text": "is", "start": 173, "end": 175, "id": 41}, {"text": "from", "start": 176, "end": 180, "id": 42}, {"text": "the", "start": 181, "end": 184, "id": 43}, {"text": "FDK", "start": 185, "end": 188, "id": 44}, {"text": "algorithm", "start": 189, "end": 198, "id": 45}, {"text": ".", "start": 198, "end": 199, "id": 46}]}
{"pdf_hash": "3764c442fa6356d4f542ad70b914dddafaff9834", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Contrast-enhanced computed tomographic pulmonary angiography showing a fistula between the aortic arch aneurysm and the origin of the left pulmonary artery (arrows). A. Axial view passing through the pulmonary bifurcation. B. Sagittal oblique view passing through the aortic arch. Note the contrast agent jet (same density as seen in the aorta) in the left pulmonary artery, suggesting a left-to-right shunt through the fistula.", "width": 694, "height": 1434, "subcaptions": {"a": [30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "a41868f5-1a5e-477d-9b13-c5f1fe426c8e", "label": "a", "points": [[3.9, 3.1], [3.9, 689.4], [690.2, 689.4], [690.2, 3.1]], "color": "yellow"}, {"id": "d81ee368-ffad-48d0-a4f2-14c7e0957d1c", "label": "b", "points": [[6.1, 723.9], [6.1, 1411.3], [688, 1411.3], [688, 723.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Contrast", "start": 10, "end": 18, "id": 3}, {"text": "-", "start": 18, "end": 19, "id": 4}, {"text": "enhanced", "start": 19, "end": 27, "id": 5}, {"text": "computed", "start": 28, "end": 36, "id": 6}, {"text": "tomographic", "start": 37, "end": 48, "id": 7}, {"text": "pulmonary", "start": 49, "end": 58, "id": 8}, {"text": "angiography", "start": 59, "end": 70, "id": 9}, {"text": "showing", "start": 71, "end": 78, "id": 10}, {"text": "a", "start": 79, "end": 80, "id": 11}, {"text": "fistula", "start": 81, "end": 88, "id": 12}, {"text": "between", "start": 89, "end": 96, "id": 13}, {"text": "the", "start": 97, "end": 100, "id": 14}, {"text": "aortic", "start": 101, "end": 107, "id": 15}, {"text": "arch", "start": 108, "end": 112, "id": 16}, {"text": "aneurysm", "start": 113, "end": 121, "id": 17}, {"text": "and", "start": 122, "end": 125, "id": 18}, {"text": "the", "start": 126, "end": 129, "id": 19}, {"text": "origin", "start": 130, "end": 136, "id": 20}, {"text": "of", "start": 137, "end": 139, "id": 21}, {"text": "the", "start": 140, "end": 143, "id": 22}, {"text": "left", "start": 144, "end": 148, "id": 23}, {"text": "pulmonary", "start": 149, "end": 158, "id": 24}, {"text": "artery", "start": 159, "end": 165, "id": 25}, {"text": "(", "start": 166, "end": 167, "id": 26}, {"text": "arrows", "start": 167, "end": 173, "id": 27}, {"text": ")", "start": 173, "end": 174, "id": 28}, {"text": ".", "start": 174, "end": 175, "id": 29}, {"text": "A.", "start": 176, "end": 178, "id": 30}, {"text": "Axial", "start": 179, "end": 184, "id": 31}, {"text": "view", "start": 185, "end": 189, "id": 32}, {"text": "passing", "start": 190, "end": 197, "id": 33}, {"text": "through", "start": 198, "end": 205, "id": 34}, {"text": "the", "start": 206, "end": 209, "id": 35}, {"text": "pulmonary", "start": 210, "end": 219, "id": 36}, {"text": "bifurcation", "start": 220, "end": 231, "id": 37}, {"text": ".", "start": 231, "end": 232, "id": 38}, {"text": "B.", "start": 233, "end": 235, "id": 39}, {"text": "Sagittal", "start": 236, "end": 244, "id": 40}, {"text": "oblique", "start": 245, "end": 252, "id": 41}, {"text": "view", "start": 253, "end": 257, "id": 42}, {"text": "passing", "start": 258, "end": 265, "id": 43}, {"text": "through", "start": 266, "end": 273, "id": 44}, {"text": "the", "start": 274, "end": 277, "id": 45}, {"text": "aortic", "start": 278, "end": 284, "id": 46}, {"text": "arch", "start": 285, "end": 289, "id": 47}, {"text": ".", "start": 289, "end": 290, "id": 48}, {"text": "Note", "start": 291, "end": 295, "id": 49}, {"text": "the", "start": 296, "end": 299, "id": 50}, {"text": "contrast", "start": 300, "end": 308, "id": 51}, {"text": "agent", "start": 309, "end": 314, "id": 52}, {"text": "jet", "start": 315, "end": 318, "id": 53}, {"text": "(", "start": 319, "end": 320, "id": 54}, {"text": "same", "start": 320, "end": 324, "id": 55}, {"text": "density", "start": 325, "end": 332, "id": 56}, {"text": "as", "start": 333, "end": 335, "id": 57}, {"text": "seen", "start": 336, "end": 340, "id": 58}, {"text": "in", "start": 341, "end": 343, "id": 59}, {"text": "the", "start": 344, "end": 347, "id": 60}, {"text": "aorta", "start": 348, "end": 353, "id": 61}, {"text": ")", "start": 353, "end": 354, "id": 62}, {"text": "in", "start": 355, "end": 357, "id": 63}, {"text": "the", "start": 358, "end": 361, "id": 64}, {"text": "left", "start": 362, "end": 366, "id": 65}, {"text": "pulmonary", "start": 367, "end": 376, "id": 66}, {"text": "artery", "start": 377, "end": 383, "id": 67}, {"text": ",", "start": 383, "end": 384, "id": 68}, {"text": "suggesting", "start": 385, "end": 395, "id": 69}, {"text": "a", "start": 396, "end": 397, "id": 70}, {"text": "left", "start": 398, "end": 402, "id": 71}, {"text": "-", "start": 402, "end": 403, "id": 72}, {"text": "to", "start": 403, "end": 405, "id": 73}, {"text": "-", "start": 405, "end": 406, "id": 74}, {"text": "right", "start": 406, "end": 411, "id": 75}, {"text": "shunt", "start": 412, "end": 417, "id": 76}, {"text": "through", "start": 418, "end": 425, "id": 77}, {"text": "the", "start": 426, "end": 429, "id": 78}, {"text": "fistula", "start": 430, "end": 437, "id": 79}, {"text": ".", "start": 437, "end": 438, "id": 80}]}
{"pdf_hash": "3ed2c1fdde4608088e40cb5995e370591e7a89a9", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5. Histoblots of brain sections demonstrate that clearance of rPrPSc after blockage of PrPC expression is more efficient from grey matter than white matter. Coronal brain sections, at the level of the hippocampus and thalamus (a, c) and at the cerebellum and pons (b, d), were taken from two Tg(tTA :PrP+/0)3 mice 156 days after inoculation with RML prions. One animal developed clinical symptoms (a, b), while the other, in which PrPC expression was blocked beginning at 98 days post-inoculation, remained well (c, d). In the brain of the mouse with blocked PrPC expression (c, d), substantially less PrPSc was present, most of which appeared to be in the white matter. To suppress PrPC expression, doxycycline was administered at 98 days post-inoculation in an initial single dose of 25 mg kg\u201d1 intraperitoneally, followed by 2 mg ml\u201d1 in the drinking water. 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{"pdf_hash": "afabae2303d35c5ab40b59db243ca6e86ed07030", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Contrast enhanced computerized tomography (CT) scan shows a mass on the left kidney, and malignant thrombosis of the renal vein and inferior vena cava prior to radiation therapy. (B) The CT scan at the eight- and (C) 11-month follow-up.", "width": 634, "height": 1218, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 52, 53, 54, 55], "c": [41, 42, 43, 44, 45, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "5119020b-a5db-4c48-b04b-d05fdc0d93c0", "label": "a", "points": [[36.6, 8.8], [36.6, 360.4], [626.5, 360.4], [626.5, 8.8]], "color": "yellow"}, {"id": "5f0d85e6-2df8-4cb8-8dd3-481b163368d3", "label": "b", "points": [[35.6, 398.4], [35.6, 731.9], [626.5, 731.9], [626.5, 398.4]], "color": "cyan"}, {"id": "e1302e56-d411-4071-8930-7dcd13848666", "label": "c", "points": [[43.6, 766.5], [43.6, 1208.2], [619.5, 1208.2], [619.5, 766.5]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Contrast", "start": 14, "end": 22, "id": 6}, {"text": "enhanced", "start": 23, "end": 31, "id": 7}, {"text": "computerized", "start": 32, "end": 44, "id": 8}, {"text": "tomography", "start": 45, "end": 55, "id": 9}, {"text": "(", "start": 56, "end": 57, "id": 10}, {"text": "CT", "start": 57, "end": 59, "id": 11}, {"text": ")", "start": 59, "end": 60, "id": 12}, {"text": "scan", "start": 61, "end": 65, "id": 13}, {"text": "shows", "start": 66, "end": 71, "id": 14}, {"text": "a", "start": 72, "end": 73, "id": 15}, {"text": "mass", "start": 74, "end": 78, "id": 16}, {"text": "on", "start": 79, "end": 81, "id": 17}, {"text": "the", "start": 82, "end": 85, "id": 18}, {"text": "left", "start": 86, "end": 90, "id": 19}, {"text": "kidney", "start": 91, "end": 97, "id": 20}, {"text": ",", "start": 97, "end": 98, "id": 21}, {"text": "and", "start": 99, "end": 102, "id": 22}, {"text": "malignant", "start": 103, "end": 112, "id": 23}, {"text": "thrombosis", "start": 113, "end": 123, "id": 24}, {"text": "of", "start": 124, "end": 126, "id": 25}, {"text": "the", "start": 127, "end": 130, "id": 26}, {"text": "renal", "start": 131, "end": 136, "id": 27}, {"text": "vein", "start": 137, "end": 141, "id": 28}, {"text": "and", "start": 142, "end": 145, "id": 29}, {"text": "inferior", "start": 146, "end": 154, "id": 30}, {"text": "vena", "start": 155, "end": 159, "id": 31}, {"text": "cava", "start": 160, "end": 164, "id": 32}, {"text": "prior", "start": 165, "end": 170, "id": 33}, {"text": "to", "start": 171, "end": 173, "id": 34}, {"text": "radiation", "start": 174, "end": 183, "id": 35}, {"text": "therapy", "start": 184, "end": 191, "id": 36}, {"text": ".", "start": 191, "end": 192, "id": 37}, {"text": "(", "start": 193, "end": 194, "id": 38}, {"text": "B", "start": 194, "end": 195, "id": 39}, {"text": ")", "start": 195, "end": 196, "id": 40}, {"text": "The", "start": 197, "end": 200, "id": 41}, {"text": "CT", "start": 201, "end": 203, "id": 42}, {"text": "scan", "start": 204, "end": 208, "id": 43}, {"text": "at", "start": 209, "end": 211, "id": 44}, {"text": "the", "start": 212, "end": 215, "id": 45}, {"text": "eight-", "start": 216, "end": 222, "id": 46}, {"text": "and", "start": 223, "end": 226, "id": 47}, {"text": "(", "start": 227, "end": 228, "id": 48}, {"text": "C", "start": 228, "end": 229, "id": 49}, {"text": ")", "start": 229, "end": 230, "id": 50}, {"text": "11-month", "start": 231, "end": 239, "id": 51}, {"text": "follow", "start": 240, "end": 246, "id": 52}, {"text": "-", "start": 246, "end": 247, "id": 53}, {"text": "up", "start": 247, "end": 249, "id": 54}, {"text": ".", "start": 249, "end": 250, "id": 55}]}
{"pdf_hash": "2e501a2adb3d9d5bf5a8027c56f73ebb34e02a39", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5 Abnormal microtubule arrangements in cilia cross-sections. Ciliary axoneme abnormalities were tallied in 224 control-treated and 234 MWCNT-treated cross-sections from a single donor. Sections were categorized as normal cilia (represented in panel a), axoneme abnormalities (represented in panel b, arrow points to singlet), or dynein arm abnormalities (not found). While MWCNT treatment increased axoneme abnormalities above control levels by 3-fold (6.0% vs 1.9%), the absolute numbers of abnormal cilia in MWCNT treated cells are not sufficient to alter cilia beating/clearance. Ultrastructural imaging was also used to verify the presence of MWCNTs within the cell 24 h after treatment of undifferentiated cultures. 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{"pdf_hash": "6237b73822d451ad3df9214e012b63b5da6b82e2", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5. Distribution of CCK binding sites in the caudal guinea pig olfactory bulb. A, Brightfield photomicrograph of an autoradiogram of the dorsolateral quadrant of the olfactory bulb (coronal plane). B, Darkfield photomicrograph of the autoradiogram shown in A. C, Darkfield photomicrograph of an autoradiogram generated from a tissue section consecutive to the one shown in A and incubated with 50 pM [\u201c%]CCK-33 and 10m7 M CCK-8 to produce an image of the nonspecific binding. The low density of grains over the area of the lateral olfactory tract (LOT) suggests that the nonspecific binding was relatively low. The arrowheads indicate the transition area between the LOT and the plexiform layer of the anterior olfactory nucleus (AON). See the text for discussion. 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{"pdf_hash": "ee2269c0e26365e0fc0aaa3ead621a1a49f9d81e", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1 Traditional serrated adenoma with cytologic dysplasia. (a) A traditional serrated adenoma with villous growth and bulbous villous tips. The lining cells showed slender columnar cells with eosinophilic cytoplasm. (b) Prominent surface serration with many abortive ectopic crypts (arrows). (c) A traditional serrated adenoma with high-grade serrated dysplasia. Note the complex infoldings of ectopic crypts and occasional micropapillary structures. (d) At higher power, the cells show oval nuclei, vesicular chromatin, thickened nuclear membrane and occasional prominent nucleoli. (e) A traditional serrated adenoma (left part) showed transition to conventional adenomatous dysplasia at right part of the figure (arrows). (f) Traditional serrated adenoma with an overall conventional tubulovillous adenomatous structure. 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{"pdf_hash": "b075805fd68a3127ca8fb1371f0464513c85dd0f", "fig_key": "Figure5", "fig_uri": "11-Figure5-1.png", "text": "Figure 5: (A) POD 8 chest x-ray (first recipient) following allogeneic lung Tx. The arrows demonstrate areas of consolidation within the graft. (B) Pathological examination revealed infiltration of the graft with inflammatory cells and lymphocytes, suggesting pneumonia and cellular rejection. (C) POD 15 chest x-ray (second recipient) and (D) POD 16 chest x-ray (third recipient) demonstrating clear aeration of the lung allografts. (E) POD 29 chest x-ray (second recipient). Arrows depict caudal displacement of the left hemidiaphragm, suggesting enlargement of the graft. Arrowheads demonstrate displacement of the trachea to the right. Consolidation was found diffusely, especially in the left upper lung, suggesting atelectasis and subsequent pneumonia. (F) Necropsy findings of the native lung (right) and lung graft (left). The graft enlarged more than that of native lung, especially caudally. Arrows indicate the compressed upper lobe of the graft, which enlarged toward the mediastinum. (G\u2013K) Representative pathological findings of the native and grafted lung: (G) Bleeding, neutrophil infiltration, and cellular debris were seen, indicating pneumonia. (H) Mild bronchiolitis in the lower lobe of the graft. (I) Mild pneumonia in the upper lobe of the native lung. (J) There were well-aerated regions and lobular pneumonia regions in the upper lobe of the graft. Evidence of pneumonia extended from the pleural region (arrow heads). (K) No evidence of cellular rejection was found in the graft. 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{"pdf_hash": "a86a8a14431056304735f982612a1a22a0ba6423", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1 MRI on admittance in intensive care unit. (A) Axial T1-weighted images with gadolinium showing multiple extracardiac nodular masses located between the right atrium and the pulmonary artery, associated with pericardial effusion. Areas of marked central necrosis were surrounded by gadolinium-enhancing hypervascular lesions (red arrow). 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{"pdf_hash": "7262a259506644f2c02cb2d6dd55e03188eef464", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "FIGURE 5 Distr ibut ion of nuclear material at various times dur ing sporulation of cyr l -2 homozygous d ip lo id cells at 33.5\u00b0C. AM77 cells were incubated in sporulat ion medium at 33.5\u00b0C for 0 (a and a'), 6 (b and b'), 8 (c and c'), 10 (d and d') , 12 (e and e'), and 16 ( l and f') h. Sporulating cells stained with prop id ium iodide were photographed under phase-contrast/f luorescent (a ' - f ' ) and fluorescent (a-f) microscope, a and a ', a d ip lo id cell; b and b ' , a cell containing a large part of nuclear material (an early stage of meiosis I); c and c ' , a cell containing two parts of nuclear material (a late stage of meiosis I); d and d ' , a cell containing four parts of nuclear material (a late stage of meiosis II); e and e ' , a cell containing two parts of nuclear material and two prospores; f and f ' , a two-spored ascus. 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{"pdf_hash": "32d2070ff96a66b7adab6b3aa710ec9661bf40f8", "fig_key": "Figure9", "fig_uri": "8-Figure9-1.png", "text": "Figure 9. Polymicrogyria. Coronal T 1 weighted three-dimensional magnetization prepared rapid gradient echo (a), T 2 fluidattenuated inversion-recovery (b) and double inversion recovery (DIR) (c) images. An area of abnormal gyral pattern with irregular contours is present in the right temporal lobe (arrows), consistent with polymicrogyria. On all images, including DIR, there is no appreciable difference in the signal intensity of the normal and abnormal cortex. Note also mild atrophy of the ipsilateral hippocampus, without associated signal abnormality. 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{"pdf_hash": "a18423da54475bbc4f0d5cdfb43a3bec6a9fce06", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Initial recurrence before crizotinib therapy: (A) a 0.63-mm slice thickness spiral axial image of the chest with intravenous iodinated contrast demonstrates a well-defined 8-mm right middle lobe lung nodule consistent with metastatic disease (arrow); and (B) an 8-mm maximum intensity projection (MIP) image with clear delineation of a 4.5-mm right lower lobe pulmonary metastasis in relationship to the pulmonary vasculature (arrow). Two months after initiation of crizotinib therapy: (C ) a 0.63-mm spiral axial image with reduction in the size of the right middle lobe nodule (5.3 mm, arrow); and (D) a thin section axial image with decrease in size of the right lower lobe nodule, now 2.4 mm (arrow). Twenty-one months after initiation of crizotinib therapy: (E) residual linear scarring is noted in the region of the original right middle lobe metastasis; and (F ) no clear residual nodule seen in the right lower lobe. 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{"pdf_hash": "6064e3bab57fb5ecac0e345efd0e4d3304a60505", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A and B) Normal cranial magnetic resonance imaging and (C and D) flair and diffusion weighted images showing acute left parietal infarction.", "width": 846, "height": 650, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "01438199-c9fa-4d63-bb65-88fdd9f4b055", "label": "a", "points": [[48.3, 11.1], [48.3, 307.8], [427.9, 307.8], [427.9, 11.1]], "color": "yellow"}, {"id": "79bbdd3d-351c-4137-a6f1-2164ece9c806", "label": "a", "points": [[465.3, 8.5], [465.3, 306.5], [816.8, 306.5], [816.8, 8.5]], "color": "cyan"}, {"id": "33162997-41d7-47e4-ac37-44d200e4ceea", "label": "b", "points": [[49.7, 315.9], [49.7, 605.9], [426.6, 605.9], [426.6, 315.9]], "color": "magenta"}, {"id": "e4ad709e-3c73-41f1-acba-e13a4c7b2690", "label": "b", "points": [[461.3, 321.2], [461.3, 607.2], [818.2, 607.2], [818.2, 321.2]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": "and", "start": 13, "end": 16, "id": 5}, {"text": "B", "start": 17, "end": 18, "id": 6}, {"text": ")", "start": 18, "end": 19, "id": 7}, {"text": "Normal", "start": 20, "end": 26, "id": 8}, {"text": "cranial", "start": 27, "end": 34, "id": 9}, {"text": "magnetic", "start": 35, "end": 43, "id": 10}, {"text": "resonance", "start": 44, "end": 53, "id": 11}, {"text": "imaging", "start": 54, "end": 61, "id": 12}, {"text": "and", "start": 62, "end": 65, "id": 13}, {"text": "(", "start": 66, "end": 67, "id": 14}, {"text": "C", "start": 67, "end": 68, "id": 15}, {"text": "and", "start": 69, "end": 72, "id": 16}, {"text": "D", "start": 73, "end": 74, "id": 17}, {"text": ")", "start": 74, "end": 75, "id": 18}, {"text": "flair", "start": 76, "end": 81, "id": 19}, {"text": "and", "start": 82, "end": 85, "id": 20}, {"text": "diffusion", "start": 86, "end": 95, "id": 21}, {"text": "weighted", "start": 96, "end": 104, "id": 22}, {"text": "images", "start": 105, "end": 111, "id": 23}, {"text": "showing", "start": 112, "end": 119, "id": 24}, {"text": "acute", "start": 120, "end": 125, "id": 25}, {"text": "left", "start": 126, "end": 130, "id": 26}, {"text": "parietal", "start": 131, "end": 139, "id": 27}, {"text": "infarction", "start": 140, "end": 150, "id": 28}, {"text": ".", "start": 150, "end": 151, "id": 29}]}
{"pdf_hash": "cea45b0814145f86e50deab5978ad7a4941c1d56", "fig_key": "Figure5", "fig_uri": "8-Figure5-1.png", "text": "Figure 5. Three-dimensional US rectal images obtained by the mechanical rotational mechanism, which rotated a side-firing transrectal ultrasound (TRUS) transducer around its long axis by 1808. The three-dimensional US images are viewed using the multi-planar formatting approach. (a) Clear delineation of the rectal wall. (b) Three-dimensional view of the sphincter muscles. (c) Three-dimensional view of a rectal polyp-stage T1, with the polyp invading the submucosa. 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{"pdf_hash": "da9d5323e561b1fa001adc64ff9f2051df3563e4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIGURE 1. Abdominal CT. A, Enhanced total abdomen computed tomography scan found a huge gastric GIST in antrum of stomach before operation, in March, 2014. B, Enhanced total abdomen CT scan found no signs of recurrence or metastasis for GIST 6 months after operation, in October, 2014. CT \u00bccomputed tomography, GIST \u00bc gastrointestinal stromal tumor.", "width": 986, "height": 464, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "ddfb7a13-e043-40b6-8d06-747aaa67641d", "label": "a", "points": [[49.8, 4.7], [49.8, 434.6], [484.4, 434.6], [484.4, 4.7]], "color": "yellow"}, {"id": "be7c6e6b-fe0b-423c-80ee-7c66f2914a4d", "label": "b", "points": [[517.2, 436.2], [517.2, 3.1], [953.3, 3.1], [953.3, 436.2]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Abdominal", "start": 10, "end": 19, "id": 3}, {"text": "CT", "start": 20, "end": 22, "id": 4}, {"text": ".", "start": 22, "end": 23, "id": 5}, {"text": "A", "start": 24, "end": 25, "id": 6}, {"text": ",", "start": 25, "end": 26, "id": 7}, {"text": "Enhanced", "start": 27, "end": 35, "id": 8}, {"text": "total", "start": 36, "end": 41, "id": 9}, {"text": "abdomen", "start": 42, "end": 49, "id": 10}, {"text": "computed", "start": 50, "end": 58, "id": 11}, {"text": "tomography", "start": 59, "end": 69, "id": 12}, {"text": "scan", "start": 70, "end": 74, "id": 13}, {"text": "found", "start": 75, "end": 80, "id": 14}, {"text": "a", "start": 81, "end": 82, "id": 15}, {"text": "huge", "start": 83, "end": 87, "id": 16}, {"text": "gastric", "start": 88, "end": 95, "id": 17}, {"text": "GIST", "start": 96, "end": 100, "id": 18}, {"text": "in", "start": 101, "end": 103, "id": 19}, {"text": "antrum", "start": 104, "end": 110, "id": 20}, {"text": "of", "start": 111, "end": 113, "id": 21}, {"text": "stomach", "start": 114, "end": 121, "id": 22}, {"text": "before", "start": 122, "end": 128, "id": 23}, {"text": "operation", "start": 129, "end": 138, "id": 24}, {"text": ",", "start": 138, "end": 139, "id": 25}, {"text": "in", "start": 140, "end": 142, "id": 26}, {"text": "March", "start": 143, "end": 148, "id": 27}, {"text": ",", "start": 148, "end": 149, "id": 28}, {"text": "2014", "start": 150, "end": 154, "id": 29}, {"text": ".", "start": 154, "end": 155, "id": 30}, {"text": "B", "start": 156, "end": 157, "id": 31}, {"text": ",", "start": 157, "end": 158, "id": 32}, {"text": "Enhanced", "start": 159, "end": 167, "id": 33}, {"text": "total", "start": 168, "end": 173, "id": 34}, {"text": "abdomen", "start": 174, "end": 181, "id": 35}, {"text": "CT", "start": 182, "end": 184, "id": 36}, {"text": "scan", "start": 185, "end": 189, "id": 37}, {"text": "found", "start": 190, "end": 195, "id": 38}, {"text": "no", "start": 196, "end": 198, "id": 39}, {"text": "signs", "start": 199, "end": 204, "id": 40}, {"text": "of", "start": 205, "end": 207, "id": 41}, {"text": "recurrence", "start": 208, "end": 218, "id": 42}, {"text": "or", "start": 219, "end": 221, "id": 43}, {"text": "metastasis", "start": 222, "end": 232, "id": 44}, {"text": "for", "start": 233, "end": 236, "id": 45}, {"text": "GIST", "start": 237, "end": 241, "id": 46}, {"text": "6", "start": 242, "end": 243, "id": 47}, {"text": "months", "start": 244, "end": 250, "id": 48}, {"text": "after", "start": 251, "end": 256, "id": 49}, {"text": "operation", "start": 257, "end": 266, "id": 50}, {"text": ",", "start": 266, "end": 267, "id": 51}, {"text": "in", "start": 268, "end": 270, "id": 52}, {"text": "October", "start": 271, "end": 278, "id": 53}, {"text": ",", "start": 278, "end": 279, "id": 54}, {"text": "2014", "start": 280, "end": 284, "id": 55}, {"text": ".", "start": 284, "end": 285, "id": 56}, {"text": "CT", "start": 286, "end": 288, "id": 57}, {"text": "\u00bccomputed", "start": 289, "end": 298, "id": 58}, {"text": "tomography", "start": 299, "end": 309, "id": 59}, {"text": ",", "start": 309, "end": 310, "id": 60}, {"text": "GIST", "start": 311, "end": 315, "id": 61}, {"text": "\u00bc", "start": 316, "end": 317, "id": 62}, {"text": "gastrointestinal", "start": 318, "end": 334, "id": 63}, {"text": "stromal", "start": 335, "end": 342, "id": 64}, {"text": "tumor", "start": 343, "end": 348, "id": 65}, {"text": ".", "start": 348, "end": 349, "id": 66}]}
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{"pdf_hash": "c081ab2589a02508cdefe9c7959a4753a0dbd7e3", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. A 78-year-old female patient presented with an acute left transient ischemic attack. A, Bilateral focal vessel wall lesions were observed in the middle cerebral arteries on the transverse T1-weighted volumetric isotropically reconstructed turbo spin echo acquisition image (arrows in A). Sagittal image reconstructions of the (B) right middle cerebral artery (MCA) lesion and (C) left MCA lesion showing that both lesions are eccentric. 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{"pdf_hash": "5f4276361184db6bddd2db784520756d7f1902ec", "fig_key": "Figure8", "fig_uri": "8-Figure8-1.png", "text": "Fig. 8 A 76-year-old male with anorectal melanoma. a Sagittal T2-weighted MR image shows a heterogeneous mass lesion arising from the anterior wall of the rectum (arrow). b The mass shows enhancement on the corresponding sagittal fat-suppressed T1-weighted MR image (arrow)", "width": 868, "height": 318, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "f598cb73-64e6-4437-9133-fa1dff7162df", "label": "a", "points": [[4.3, 8.7], [4.3, 309], [418.5, 309], [418.5, 8.7]], "color": "yellow"}, {"id": "1f3d632e-473a-46b0-859c-0e486f96e65e", "label": "b", "points": [[426.7, 3.2], [426.7, 310.4], [865.5, 310.4], [865.5, 3.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "8", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "76-year", "start": 9, "end": 16, "id": 4}, {"text": "-", "start": 16, "end": 17, "id": 5}, {"text": "old", "start": 17, "end": 20, "id": 6}, {"text": "male", "start": 21, "end": 25, "id": 7}, {"text": "with", "start": 26, "end": 30, "id": 8}, {"text": "anorectal", "start": 31, "end": 40, "id": 9}, {"text": "melanoma", "start": 41, "end": 49, "id": 10}, {"text": ".", "start": 49, "end": 50, "id": 11}, {"text": "a", "start": 51, "end": 52, "id": 12}, {"text": "Sagittal", "start": 53, "end": 61, "id": 13}, {"text": "T2-weighted", "start": 62, "end": 73, "id": 14}, {"text": "MR", "start": 74, "end": 76, "id": 15}, {"text": "image", "start": 77, "end": 82, "id": 16}, {"text": "shows", "start": 83, "end": 88, "id": 17}, {"text": "a", "start": 89, "end": 90, "id": 18}, {"text": "heterogeneous", "start": 91, "end": 104, "id": 19}, {"text": "mass", "start": 105, "end": 109, "id": 20}, {"text": "lesion", "start": 110, "end": 116, "id": 21}, {"text": "arising", "start": 117, "end": 124, "id": 22}, {"text": "from", "start": 125, "end": 129, "id": 23}, {"text": "the", "start": 130, "end": 133, "id": 24}, {"text": "anterior", "start": 134, "end": 142, "id": 25}, {"text": "wall", "start": 143, "end": 147, "id": 26}, {"text": "of", "start": 148, "end": 150, "id": 27}, {"text": "the", "start": 151, "end": 154, "id": 28}, {"text": "rectum", "start": 155, "end": 161, "id": 29}, {"text": "(", "start": 162, "end": 163, "id": 30}, {"text": "arrow", "start": 163, "end": 168, "id": 31}, {"text": ")", "start": 168, "end": 169, "id": 32}, {"text": ".", "start": 169, "end": 170, "id": 33}, {"text": "b", "start": 171, "end": 172, "id": 34}, {"text": "The", "start": 173, "end": 176, "id": 35}, {"text": "mass", "start": 177, "end": 181, "id": 36}, {"text": "shows", "start": 182, "end": 187, "id": 37}, {"text": "enhancement", "start": 188, "end": 199, "id": 38}, {"text": "on", "start": 200, "end": 202, "id": 39}, {"text": "the", "start": 203, "end": 206, "id": 40}, {"text": "corresponding", "start": 207, "end": 220, "id": 41}, {"text": "sagittal", "start": 221, "end": 229, "id": 42}, {"text": "fat", "start": 230, "end": 233, "id": 43}, {"text": "-", "start": 233, "end": 234, "id": 44}, {"text": "suppressed", "start": 234, "end": 244, "id": 45}, {"text": "T1-weighted", "start": 245, "end": 256, "id": 46}, {"text": "MR", "start": 257, "end": 259, "id": 47}, {"text": "image", "start": 260, "end": 265, "id": 48}, {"text": "(", "start": 266, "end": 267, "id": 49}, {"text": "arrow", "start": 267, "end": 272, "id": 50}, {"text": ")", "start": 272, "end": 273, "id": 51}]}
{"pdf_hash": "0f4bb68f75fc73b18502c654000846d58557060c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: Electron microscopy of laser-irradiated PET substrates. Upper panel: SEM images of resulting structures after excimer laser irradiation of PET substrates. Left: ripples, 6000 pulses of linear polarized KrF laser radiation ( = 248 nm) at a fluence of 9 mJ cm \u22122 . Right: walls, 30 pulses of ArF laser radiation ( = 193 nm) at fluences of 30 mJ cm \u22122 . 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{"pdf_hash": "5031308a8483488c43b36c76fa3bc0dd29a6f88f", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Figure 3. (A) Tumor arranged in the form of cellular nodules (H & E, 3 40). (B) Sheets of mononuclear cells, giant cells, and lacunar cells (highlighted by arrows; H & E, 200x). (C) Clusters of CD30-positive cells with membranous and Golgi zone positivity (immunohistochemistry, CD30, 3 200). (D) Atypical cells negative for CD45 with background lymphocytes positive (immunohistochemistry, CD45, 3 200). (E) Weak PAX5 nuclear positivity with strong positivity in lymphocytes (immunohistochemistry, PAX5, 3 200). (F) Case showing a predominantly fibrohistiocytic pattern (H & E, 3 40). (G) A high power shows histiocyte-like cells, background lymphocytes, eosinophils, and occasional Reed-Sternberg cells (shown by the arrow; H & E, 3 200). 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{"pdf_hash": "6bd33ea1a0f8bc1b0521ebb8ee74171a2d4c680f", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4 Case #3. This case selected as typical BLR case (relatively T4). Deformity of bronchus was evident. This case was finally resectable after chemotherapy. a Endoscopic findings before chemotherapy. b Computer tomography before chemotherapy. c Endoscopic findings after chemotherapy. d Endoscopic findings before chemotherapy", "width": 1182, "height": 904, "subcaptions": {"a": [33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44], "c": [45, 46, 47, 48, 49, 50], "d": [51, 52, 53, 54, 55]}, "subfigures": [{"id": "910d8a57-3d17-4015-a035-d638337a0be8", "label": "a", "points": [[0, 3.7], [0, 446.3], [513.5, 446.3], [513.5, 3.7]], "color": "yellow"}, {"id": "532459ca-94e2-4783-8283-81744daa2873", "label": "b", "points": [[519.1, 446.3], [519.1, 5.6], [1180.2, 5.6], [1180.2, 446.3]], "color": "cyan"}, {"id": "55f78ef5-26a2-471a-a860-6135821d30bc", "label": "c", "points": [[515.4, 901.9], [515.4, 457.5], [3.7, 457.5], [3.7, 901.9]], "color": "magenta"}, {"id": "132beb74-3751-45c7-9085-cd8aeafe24f5", "label": "d", "points": [[519.1, 455.6], [519.1, 900.1], [1174.6, 900.1], [1174.6, 455.6]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Case", "start": 7, "end": 11, "id": 3}, {"text": "#", "start": 12, "end": 13, "id": 4}, {"text": "3", "start": 13, "end": 14, "id": 5}, {"text": ".", "start": 14, "end": 15, "id": 6}, {"text": "This", "start": 16, "end": 20, "id": 7}, {"text": "case", "start": 21, "end": 25, "id": 8}, {"text": "selected", "start": 26, "end": 34, "id": 9}, {"text": "as", "start": 35, "end": 37, "id": 10}, {"text": "typical", "start": 38, "end": 45, "id": 11}, {"text": "BLR", "start": 46, "end": 49, "id": 12}, {"text": "case", "start": 50, "end": 54, "id": 13}, {"text": "(", "start": 55, "end": 56, "id": 14}, {"text": "relatively", "start": 56, "end": 66, "id": 15}, {"text": "T4", "start": 67, "end": 69, "id": 16}, {"text": ")", "start": 69, "end": 70, "id": 17}, {"text": ".", "start": 70, "end": 71, "id": 18}, {"text": "Deformity", "start": 72, "end": 81, "id": 19}, {"text": "of", "start": 82, "end": 84, "id": 20}, {"text": "bronchus", "start": 85, "end": 93, "id": 21}, {"text": "was", "start": 94, "end": 97, "id": 22}, {"text": "evident", "start": 98, "end": 105, "id": 23}, {"text": ".", "start": 105, "end": 106, "id": 24}, {"text": "This", "start": 107, "end": 111, "id": 25}, {"text": "case", "start": 112, "end": 116, "id": 26}, {"text": "was", "start": 117, "end": 120, "id": 27}, {"text": "finally", "start": 121, "end": 128, "id": 28}, {"text": "resectable", "start": 129, "end": 139, "id": 29}, {"text": "after", "start": 140, "end": 145, "id": 30}, {"text": "chemotherapy", "start": 146, "end": 158, "id": 31}, {"text": ".", "start": 158, "end": 159, "id": 32}, {"text": "a", "start": 160, "end": 161, "id": 33}, {"text": "Endoscopic", "start": 162, "end": 172, "id": 34}, {"text": "findings", "start": 173, "end": 181, "id": 35}, {"text": "before", "start": 182, "end": 188, "id": 36}, {"text": "chemotherapy", "start": 189, "end": 201, "id": 37}, {"text": ".", "start": 201, "end": 202, "id": 38}, {"text": "b", "start": 203, "end": 204, "id": 39}, {"text": "Computer", "start": 205, "end": 213, "id": 40}, {"text": "tomography", "start": 214, "end": 224, "id": 41}, {"text": "before", "start": 225, "end": 231, "id": 42}, {"text": "chemotherapy", "start": 232, "end": 244, "id": 43}, {"text": ".", "start": 244, "end": 245, "id": 44}, {"text": "c", "start": 246, "end": 247, "id": 45}, {"text": "Endoscopic", "start": 248, "end": 258, "id": 46}, {"text": "findings", "start": 259, "end": 267, "id": 47}, {"text": "after", "start": 268, "end": 273, "id": 48}, {"text": "chemotherapy", "start": 274, "end": 286, "id": 49}, {"text": ".", "start": 286, "end": 287, "id": 50}, {"text": "d", "start": 288, "end": 289, "id": 51}, {"text": "Endoscopic", "start": 290, "end": 300, "id": 52}, {"text": "findings", "start": 301, "end": 309, "id": 53}, {"text": "before", "start": 310, "end": 316, "id": 54}, {"text": "chemotherapy", "start": 317, "end": 329, "id": 55}]}
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{"pdf_hash": "aa494a616eb73b9ef1db4153cade8e1dc21c2661", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. A 40-year-old female patient with angioimmunoblastic T-cell lymphoma. (A) Maximum intensity projection of positron emission tomography\u2013computed tomography (PET-CT) shows multiple enlarged lymph nodes with increased fluorodeoxyglucose (FDG) uptake in the bilateral neck, axillar, retroperitoneal, iliac, and inguinal areas. Increased FDG uptakes in both lower lung fields suggest lung involvement. Transaxial PET (B) and fusion PET-CT (C) images demonstrate mild increased FDG uptake in bone marrow of iliac crests (arrows). 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{"pdf_hash": "665712de97dcc6e754cbed60a21888572c5b1953", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. Operative illustrations in endoscopic view. (A) Thecal sac and shoulder margin of contralateral traversing root was revealed. (B) Cranial tip of superior articular process (S1) is cut by angled chisel. (C) Decompressed L5 exiting root in contralateral side (left) is observed. (D) Decompressed L5 exiting root in primary ipsilateral side (right) is demonstrated. Black triangle: cranial tip of superior articular process. Asterisk: L5 exiting root (contralateral). 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{"pdf_hash": "45d42e4ec5597194f29d0dccaff59f37a2f2a167", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Figure 4. Representative backscattered SEM images of a transverse section taken at the central part of a BGSr filled hole, 60 days after the surgery, showing several isolated bone formations (arrows) inside the medullar cavity. The B and C boxed areas of A correspond to the remodeled bone (B) and to an isolated bone formation (C), at a greater magnification. The newly formed bone (darker in A) contains several irregularly shaped osteocytes (B) and includes some granules (D) consisting of calcium phosphate, as shown by the X-ray microanalysis (D). 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{"pdf_hash": "288146d411fb76af10573a95710637c7e08b1132", "fig_key": "Figure13", "fig_uri": "10-Figure13-1.png", "text": "Figure 13. MD-CT volumetry of the tibial defect in axial images: CPG group: left: defect zone is identified (line), right: only areas with a density .500 HU are opacified (white area), example of an animal with 23% bone defect consolidation. doi:10.1371/journal.pone.0100143.g013", "width": 902, "height": 422, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "4a3c32de-97d3-43f4-92d0-f46e9ed52861", "label": "a", "points": [[7.5, 5.5], [7.5, 415.9], [422.2, 415.9], [422.2, 5.5]], "color": "yellow"}, {"id": "8b7f53fe-abd8-4456-93ed-11bd781c9dc5", "label": "b", "points": [[430.7, 1.2], [430.7, 415.9], [892.4, 415.9], [892.4, 1.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "13", "start": 7, "end": 9, "id": 1}, {"text": ".", "start": 9, "end": 10, "id": 2}, {"text": "MD", "start": 11, "end": 13, "id": 3}, {"text": "-", "start": 13, "end": 14, "id": 4}, {"text": "CT", "start": 14, "end": 16, "id": 5}, {"text": "volumetry", "start": 17, "end": 26, "id": 6}, {"text": "of", "start": 27, "end": 29, "id": 7}, {"text": "the", "start": 30, "end": 33, "id": 8}, {"text": "tibial", "start": 34, "end": 40, "id": 9}, {"text": "defect", "start": 41, "end": 47, "id": 10}, {"text": "in", "start": 48, "end": 50, "id": 11}, {"text": "axial", "start": 51, "end": 56, "id": 12}, {"text": "images", "start": 57, "end": 63, "id": 13}, {"text": ":", "start": 63, "end": 64, "id": 14}, {"text": "CPG", "start": 65, "end": 68, "id": 15}, {"text": "group", "start": 69, "end": 74, "id": 16}, {"text": ":", "start": 74, "end": 75, "id": 17}, {"text": "left", "start": 76, "end": 80, "id": 18}, {"text": ":", "start": 80, "end": 81, "id": 19}, {"text": "defect", "start": 82, "end": 88, "id": 20}, {"text": "zone", "start": 89, "end": 93, "id": 21}, {"text": "is", "start": 94, "end": 96, "id": 22}, {"text": "identified", "start": 97, "end": 107, "id": 23}, {"text": "(", "start": 108, "end": 109, "id": 24}, {"text": "line", "start": 109, "end": 113, "id": 25}, {"text": ")", "start": 113, "end": 114, "id": 26}, {"text": ",", "start": 114, "end": 115, "id": 27}, {"text": "right", "start": 116, "end": 121, "id": 28}, {"text": ":", "start": 121, "end": 122, "id": 29}, {"text": "only", "start": 123, "end": 127, "id": 30}, {"text": "areas", "start": 128, "end": 133, "id": 31}, {"text": "with", "start": 134, "end": 138, "id": 32}, {"text": "a", "start": 139, "end": 140, "id": 33}, {"text": "density", "start": 141, "end": 148, "id": 34}, {"text": ".500", "start": 149, "end": 153, "id": 35}, {"text": "HU", "start": 154, "end": 156, "id": 36}, {"text": "are", "start": 157, "end": 160, "id": 37}, {"text": "opacified", "start": 161, "end": 170, "id": 38}, {"text": "(", "start": 171, "end": 172, "id": 39}, {"text": "white", "start": 172, "end": 177, "id": 40}, {"text": "area", "start": 178, "end": 182, "id": 41}, {"text": ")", "start": 182, "end": 183, "id": 42}, {"text": ",", "start": 183, "end": 184, "id": 43}, {"text": "example", "start": 185, "end": 192, "id": 44}, {"text": "of", "start": 193, "end": 195, "id": 45}, {"text": "an", "start": 196, "end": 198, "id": 46}, {"text": "animal", "start": 199, "end": 205, "id": 47}, {"text": "with", "start": 206, "end": 210, "id": 48}, {"text": "23", "start": 211, "end": 213, "id": 49}, {"text": "%", "start": 213, "end": 214, "id": 50}, {"text": "bone", "start": 215, "end": 219, "id": 51}, {"text": "defect", "start": 220, "end": 226, "id": 52}, {"text": "consolidation", "start": 227, "end": 240, "id": 53}, {"text": ".", "start": 240, "end": 241, "id": 54}, {"text": "doi:10.1371", "start": 242, "end": 253, "id": 55}, {"text": "/", "start": 253, "end": 254, "id": 56}, {"text": "journal.pone.0100143.g013", "start": 254, "end": 279, "id": 57}]}
{"pdf_hash": "f2f999cb54fbbd18ca53de9125e78c16831d03fd", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Variation in morphometric characteristics seen on pre-operative CT scan in two age-matched males of similar size, with similar comorbid conditions. CT on the left demonstrating high psoas muscle area, CT on the right demonstrating low psoas muscle area, both with respect to the mean.", "width": 1222, "height": 442, "subcaptions": {"a": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "491de44a-6d12-495f-9968-af9754d68bf3", "label": "a", "points": [[14.1, 1.7], [14.1, 438], [600.9, 438], [600.9, 1.7]], "color": "yellow"}, {"id": "24e2a7ce-f592-4041-b888-62ce3bb49b80", "label": "b", "points": [[618.3, 1.7], [618.3, 438], [1214.8, 438], [1214.8, 1.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Variation", "start": 8, "end": 17, "id": 4}, {"text": "in", "start": 18, "end": 20, "id": 5}, {"text": "morphometric", "start": 21, "end": 33, "id": 6}, {"text": "characteristics", "start": 34, "end": 49, "id": 7}, {"text": "seen", "start": 50, "end": 54, "id": 8}, {"text": "on", "start": 55, "end": 57, "id": 9}, {"text": "pre", "start": 58, "end": 61, "id": 10}, {"text": "-", "start": 61, "end": 62, "id": 11}, {"text": "operative", "start": 62, "end": 71, "id": 12}, {"text": "CT", "start": 72, "end": 74, "id": 13}, {"text": "scan", "start": 75, "end": 79, "id": 14}, {"text": "in", "start": 80, "end": 82, "id": 15}, {"text": "two", "start": 83, "end": 86, "id": 16}, {"text": "age", "start": 87, "end": 90, "id": 17}, {"text": "-", "start": 90, "end": 91, "id": 18}, {"text": "matched", "start": 91, "end": 98, "id": 19}, {"text": "males", "start": 99, "end": 104, "id": 20}, {"text": "of", "start": 105, "end": 107, "id": 21}, {"text": "similar", "start": 108, "end": 115, "id": 22}, {"text": "size", "start": 116, "end": 120, "id": 23}, {"text": ",", "start": 120, "end": 121, "id": 24}, {"text": "with", "start": 122, "end": 126, "id": 25}, {"text": "similar", "start": 127, "end": 134, "id": 26}, {"text": "comorbid", "start": 135, "end": 143, "id": 27}, {"text": "conditions", "start": 144, "end": 154, "id": 28}, {"text": ".", "start": 154, "end": 155, "id": 29}, {"text": "CT", "start": 156, "end": 158, "id": 30}, {"text": "on", "start": 159, "end": 161, "id": 31}, {"text": "the", "start": 162, "end": 165, "id": 32}, {"text": "left", "start": 166, "end": 170, "id": 33}, {"text": "demonstrating", "start": 171, "end": 184, "id": 34}, {"text": "high", "start": 185, "end": 189, "id": 35}, {"text": "psoas", "start": 190, "end": 195, "id": 36}, {"text": "muscle", "start": 196, "end": 202, "id": 37}, {"text": "area", "start": 203, "end": 207, "id": 38}, {"text": ",", "start": 207, "end": 208, "id": 39}, {"text": "CT", "start": 209, "end": 211, "id": 40}, {"text": "on", "start": 212, "end": 214, "id": 41}, {"text": "the", "start": 215, "end": 218, "id": 42}, {"text": "right", "start": 219, "end": 224, "id": 43}, {"text": "demonstrating", "start": 225, "end": 238, "id": 44}, {"text": "low", "start": 239, "end": 242, "id": 45}, {"text": "psoas", "start": 243, "end": 248, "id": 46}, {"text": "muscle", "start": 249, "end": 255, "id": 47}, {"text": "area", "start": 256, "end": 260, "id": 48}, {"text": ",", "start": 260, "end": 261, "id": 49}, {"text": "both", "start": 262, "end": 266, "id": 50}, {"text": "with", "start": 267, "end": 271, "id": 51}, {"text": "respect", "start": 272, "end": 279, "id": 52}, {"text": "to", "start": 280, "end": 282, "id": 53}, {"text": "the", "start": 283, "end": 286, "id": 54}, {"text": "mean", "start": 287, "end": 291, "id": 55}, {"text": ".", "start": 291, "end": 292, "id": 56}]}
{"pdf_hash": "d2842c17d22e5832fecc655b8fcd71ea1ceb9d06", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. A 75-year-old asymptomatic woman underwent breast ultrasonography and digital mammography. (A) Screening breast ultrasonography shows an indistinct hypoechoic nodule in the right upper inner periareolar portion. Thus, we recommended diagnostic mammography after marking the lesion with a round metal marker. (B, C, D) Right mediolateral oblique and craniocaudal views (B and C) show a spiculated, isodense nodule (arrow) unmarked by computer-aided detection (CAD); however, CAD marked another lesion (D-asterisk, \u2018*\u2019) in the upper portion and benign vascular calcifications (D-triangle, \u2018\u25b2\u2019) in the outer portion. 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{"pdf_hash": "16377b40010e0ccf57241db2e2d5f15fdb2e8897", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "FIG. 2. Heat maps for the model predicted relative probabilities of (a) coyote use, (b) coyote removal risk, and (c) deer use on Monroe Mountain in Fishlake National Forest, UT. Dark to light is low to high probability, respectively. The x-y coordinates are in Universal Transverse Mercator (UTM Zone 12N, datum NAD83).", "width": 1236, "height": 830, "subcaptions": {"a": [13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25], "c": [27, 28, 29, 30, 31]}, "subfigures": [{"id": "ea84939d-9705-4443-96eb-2528c651f83a", "label": "a", "points": [[51.8, 54.4], [51.8, 757.3], [424.8, 757.3], [424.8, 54.4]], "color": "yellow"}, {"id": "59163bed-198b-4523-9263-bc3aa695956f", "label": "b", "points": [[446.2, 56.3], [446.2, 767], [803.5, 767], [803.5, 56.3]], "color": "cyan"}, {"id": "64ddfbcd-c398-4b00-a97f-15b5406effef", "label": "c", "points": [[828.9, 46.5], [828.9, 767], [1217.5, 767], [1217.5, 46.5]], "color": "magenta"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Heat", "start": 8, "end": 12, "id": 4}, {"text": "maps", "start": 13, "end": 17, "id": 5}, {"text": "for", "start": 18, "end": 21, "id": 6}, {"text": "the", "start": 22, "end": 25, "id": 7}, {"text": "model", "start": 26, "end": 31, "id": 8}, {"text": "predicted", "start": 32, "end": 41, "id": 9}, {"text": "relative", "start": 42, "end": 50, "id": 10}, {"text": "probabilities", "start": 51, "end": 64, "id": 11}, {"text": "of", "start": 65, "end": 67, "id": 12}, {"text": "(", "start": 68, "end": 69, "id": 13}, {"text": "a", "start": 69, "end": 70, "id": 14}, {"text": ")", "start": 70, "end": 71, "id": 15}, {"text": "coyote", "start": 72, "end": 78, "id": 16}, {"text": "use", "start": 79, "end": 82, "id": 17}, {"text": ",", "start": 82, "end": 83, "id": 18}, {"text": "(", "start": 84, "end": 85, "id": 19}, {"text": "b", "start": 85, "end": 86, "id": 20}, {"text": ")", "start": 86, "end": 87, "id": 21}, {"text": "coyote", "start": 88, "end": 94, "id": 22}, {"text": "removal", "start": 95, "end": 102, "id": 23}, {"text": "risk", "start": 103, "end": 107, "id": 24}, {"text": ",", "start": 107, "end": 108, "id": 25}, {"text": "and", "start": 109, "end": 112, "id": 26}, {"text": "(", "start": 113, "end": 114, "id": 27}, {"text": "c", "start": 114, "end": 115, "id": 28}, {"text": ")", "start": 115, "end": 116, "id": 29}, {"text": "deer", "start": 117, "end": 121, "id": 30}, {"text": "use", "start": 122, "end": 125, "id": 31}, {"text": "on", "start": 126, "end": 128, "id": 32}, {"text": "Monroe", "start": 129, "end": 135, "id": 33}, {"text": "Mountain", "start": 136, "end": 144, "id": 34}, {"text": "in", "start": 145, "end": 147, "id": 35}, {"text": "Fishlake", "start": 148, "end": 156, "id": 36}, {"text": "National", "start": 157, "end": 165, "id": 37}, {"text": "Forest", "start": 166, "end": 172, "id": 38}, {"text": ",", "start": 172, "end": 173, "id": 39}, {"text": "UT", "start": 174, "end": 176, "id": 40}, {"text": ".", "start": 176, "end": 177, "id": 41}, {"text": "Dark", "start": 178, "end": 182, "id": 42}, {"text": "to", "start": 183, "end": 185, "id": 43}, {"text": "light", "start": 186, "end": 191, "id": 44}, {"text": "is", "start": 192, "end": 194, "id": 45}, {"text": "low", "start": 195, "end": 198, "id": 46}, {"text": "to", "start": 199, "end": 201, "id": 47}, {"text": "high", "start": 202, "end": 206, "id": 48}, {"text": "probability", "start": 207, "end": 218, "id": 49}, {"text": ",", "start": 218, "end": 219, "id": 50}, {"text": "respectively", "start": 220, "end": 232, "id": 51}, {"text": ".", "start": 232, "end": 233, "id": 52}, {"text": "The", "start": 234, "end": 237, "id": 53}, {"text": "x", "start": 238, "end": 239, "id": 54}, {"text": "-", "start": 239, "end": 240, "id": 55}, {"text": "y", "start": 240, "end": 241, "id": 56}, {"text": "coordinates", "start": 242, "end": 253, "id": 57}, {"text": "are", "start": 254, "end": 257, "id": 58}, {"text": "in", "start": 258, "end": 260, "id": 59}, {"text": "Universal", "start": 261, "end": 270, "id": 60}, {"text": "Transverse", "start": 271, "end": 281, "id": 61}, {"text": "Mercator", "start": 282, "end": 290, "id": 62}, {"text": "(", "start": 291, "end": 292, "id": 63}, {"text": "UTM", "start": 292, "end": 295, "id": 64}, {"text": "Zone", "start": 296, "end": 300, "id": 65}, {"text": "12N", "start": 301, "end": 304, "id": 66}, {"text": ",", "start": 304, "end": 305, "id": 67}, {"text": "datum", "start": 306, "end": 311, "id": 68}, {"text": "NAD83", "start": 312, "end": 317, "id": 69}, {"text": ")", "start": 317, "end": 318, "id": 70}, {"text": ".", "start": 318, "end": 319, "id": 71}]}
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{"pdf_hash": "ac6fdcbe42f7ae3743d1e1d968bdf53ba6a094dd", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5 Congenital scoliosis with fused ribs treated using VEPTR. Expansion thoracotomy was conducted by dividing the fused ribs. a Radiograph before surgery. b 3-dimensional CT showing congenital fused ribs and vertebrae. c Intraoperative photo showing expansion thoracotomy and placement of VEPTR. d Radiograph after surgery", "width": 1000, "height": 1126, "subcaptions": {"a": [22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "c": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "d": [48, 49, 50, 51]}, "subfigures": [{"id": "a94c2465-efdc-4211-9044-7770a83e9bda", "label": "a", "points": [[4, 1.3], [4, 622.1], [490.6, 622.1], [490.6, 1.3]], "color": "yellow"}, {"id": "2072f5b4-1e67-4f9b-a0bc-ff7efc9bd8ee", "label": "b", "points": [[5.6, 636.4], [5.6, 1122.9], [493.7, 1122.9], [493.7, 636.4]], "color": "cyan"}, {"id": "844bdfed-0ab8-4206-b938-35f42d289da6", "label": "c", "points": [[503.2, 2.9], [503.2, 372.5], [997.6, 372.5], [997.6, 2.9]], "color": "magenta"}, {"id": "87597fc1-2ada-49d3-a7ef-db316a010732", "label": "d", "points": [[506.3, 383.6], [506.3, 953.9], [994.5, 953.9], [994.5, 383.6]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": "Congenital", "start": 7, "end": 17, "id": 3}, {"text": "scoliosis", "start": 18, "end": 27, "id": 4}, {"text": "with", "start": 28, "end": 32, "id": 5}, {"text": "fused", "start": 33, "end": 38, "id": 6}, {"text": "ribs", "start": 39, "end": 43, "id": 7}, {"text": "treated", "start": 44, "end": 51, "id": 8}, {"text": "using", "start": 52, "end": 57, "id": 9}, {"text": "VEPTR", "start": 58, "end": 63, "id": 10}, {"text": ".", "start": 63, "end": 64, "id": 11}, {"text": "Expansion", "start": 65, "end": 74, "id": 12}, {"text": "thoracotomy", "start": 75, "end": 86, "id": 13}, {"text": "was", "start": 87, "end": 90, "id": 14}, {"text": "conducted", "start": 91, "end": 100, "id": 15}, {"text": "by", "start": 101, "end": 103, "id": 16}, {"text": "dividing", "start": 104, "end": 112, "id": 17}, {"text": "the", "start": 113, "end": 116, "id": 18}, {"text": "fused", "start": 117, "end": 122, "id": 19}, {"text": "ribs", "start": 123, "end": 127, "id": 20}, {"text": ".", "start": 127, "end": 128, "id": 21}, {"text": "a", "start": 129, "end": 130, "id": 22}, {"text": "Radiograph", "start": 131, "end": 141, "id": 23}, {"text": "before", "start": 142, "end": 148, "id": 24}, {"text": "surgery", "start": 149, "end": 156, "id": 25}, {"text": ".", "start": 156, "end": 157, "id": 26}, {"text": "b", "start": 158, "end": 159, "id": 27}, {"text": "3-dimensional", "start": 160, "end": 173, "id": 28}, {"text": "CT", "start": 174, "end": 176, "id": 29}, {"text": "showing", "start": 177, "end": 184, "id": 30}, {"text": "congenital", "start": 185, "end": 195, "id": 31}, {"text": "fused", "start": 196, "end": 201, "id": 32}, {"text": "ribs", "start": 202, "end": 206, "id": 33}, {"text": "and", "start": 207, "end": 210, "id": 34}, {"text": "vertebrae", "start": 211, "end": 220, "id": 35}, {"text": ".", "start": 220, "end": 221, "id": 36}, {"text": "c", "start": 222, "end": 223, "id": 37}, {"text": "Intraoperative", "start": 224, "end": 238, "id": 38}, {"text": "photo", "start": 239, "end": 244, "id": 39}, {"text": "showing", "start": 245, "end": 252, "id": 40}, {"text": "expansion", "start": 253, "end": 262, "id": 41}, {"text": "thoracotomy", "start": 263, "end": 274, "id": 42}, {"text": "and", "start": 275, "end": 278, "id": 43}, {"text": "placement", "start": 279, "end": 288, "id": 44}, {"text": "of", "start": 289, "end": 291, "id": 45}, {"text": "VEPTR", "start": 292, "end": 297, "id": 46}, {"text": ".", "start": 297, "end": 298, "id": 47}, {"text": "d", "start": 299, "end": 300, "id": 48}, {"text": "Radiograph", "start": 301, "end": 311, "id": 49}, {"text": "after", "start": 312, "end": 317, "id": 50}, {"text": "surgery", "start": 318, "end": 325, "id": 51}]}
{"pdf_hash": "cb3f02074adcc3b28943cb3f422080ef33759357", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 (a, b) Confocal longitudinal OCT B-scan passing close to the fovea (length 8 mm, 8 mm lateral resolution). A hyper-reflective area near the abnormal vessel distorts the normal layered retinal disposition. Pinpoints of higher reflectivity are detectable inside this area (c) Confocal coronal OCT C-scan (8 mm lateral resolution) and (d) overlay of simultaneous pixel-to--pixel corresponding C-scan and red-free image. 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{"pdf_hash": "0db069b0f36d7113493364e0d5544ad8091dd5ae", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Pathology of pericardium and computed tomography (CT) images at 4 months and 1 year after surgical resection. (A) Tissue from the pericardium and adjacent atrium strained with hematoxylin and eosin staining (original magnification: left panel, x50; and right panel, x100) revealed diffuse infiltration of the pericardium by epithelioid cells in papillary arrangements. The tumor cells were characterized by abundant cytoplasm, prominent nuclei and cytoplasmic vacuoles. (B) No pericardial effusion and little pleural effusion were observed at 4 months after the operation on contrast-enhanced CT (left panel, lung window; and right panel, mediastinal window). (C) Multiple lung metastases and a large pleural effusion were found at 1 year postoperatively (left panel, lung window; and right panel, mediastinal window).", "width": 890, "height": 1154, "subcaptions": {"a": [82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119], "b": [120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151]}, "subfigures": [{"id": "36aa41ac-30e8-424e-b613-36c7dd3cc4b0", "label": "a", "points": [[71.9, 8.9], [71.9, 312.6], [467, 312.6], [467, 8.9]], "color": "yellow"}, {"id": "af0c04a4-7620-4f67-b88e-e75214e43c67", "label": "a", "points": [[468.4, 3.3], [468.4, 315.4], [860.7, 315.4], [860.7, 3.3]], "color": "cyan"}, {"id": "5a74b8c8-1e61-4bbb-84df-952e89408bf6", "label": "b", "points": [[66.3, 324.3], [66.3, 708.2], [457.2, 708.2], [457.2, 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{"pdf_hash": "6fe887c4339e35d64d75da70c25fe136c233368b", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. Patient 63: A 22 yrs old male, presenting with medically refractory temporal lobe seizures, showing a left temporal lesion with peri-lesional hypointense signal in T2-weighted axial (A), coronal (B) MRI scans as well as in the T1-weighted saggital MPRAGE sequence (C) (postoperative histology: ganglioglioma WHO Grade I). Preoperative neuronavigation plan and projection of the lesion on to the skin (D) before beginning of surgery: The photograph demonstrates the projection of the segmented tumour volume (green lines) onto the skin of the left temporal region, just in front of the external auditory canal (left side), zygoma on the top. Black line represents the base of the question mark temporal skin incision. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of the article.)", "width": 1000, "height": 772, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 43, 44, 66], "b": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 39, 40, 41, 42, 43, 44, 66], "c": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "d": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "4d76e579-289c-4d44-a5c9-cfe36dc70018", "label": "a", 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{"pdf_hash": "6c507a97e1902ca07b7b0c52ddf0d832f128a4d7", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Possible cerebral microinfarct (CMI) at 7.0 T in vivo magnetic resonance imaging (MRI). A possible cortical CMI in a 76-year-old nondemented male is represented as a hyperintense cortical lesion on a fluid attenuated inversion recovery (FLAIR) (A; 0.8 \u00c2 0.8 \u00c2 0.8 mm 3 ) and a T 2 weighted (B; 0.7 \u00c2 0.7 \u00c2 0.7 mm 3 ), and as a hypointense lesion on a T 1 weighted (C; 1.0 \u00c2 1.0 \u00c2 1.0 mm 3 ) magnetic resonance (MR) image on a sagittal view of the brain. 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{"pdf_hash": "5af56a632713e480046fb5c2a25a0106fa6675f8", "fig_key": "Figure6", "fig_uri": "24-Figure6-1.png", "text": "Figure 6. Expression of Merkel cell polyomavirus (MCV) tumor antigen (T antigen) proteins in Merkel cell carcinoma (MCC). (a) Immunostaining with anti-MCV large T antigen (LT) shows nests of MCC tumor cells infiltrating the dermis (20\u00d7 magnification). (b) Oil emersion demonstrates the robust expression of MCV LT localized to the nuclear compartment of tumor cells (100\u00d7 magnification). (c,d) Differential expression of LT and small T antigen (sT) in a case of MCC. Sequential sections of a polymerase chain reaction\u2013 confirmed, MCV DNA\u2013positive MCC stained with (c) anti-MCV LT and (d) anti-MCV sT antibodies. Although LT expression was not detected in this lesion, sT expression is clearly seen. 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{"pdf_hash": "3bb554141fcd4aa7c6b0f2219dc1fd3838bf8853", "fig_key": "Figure17", "fig_uri": "11-Figure17-1.png", "text": "Figure 17 A seventy-one-year-old man, with a status of post endovascular stent repair of infrarenal aortic aneurysm. The non-contrast axial CT (A) image shows large infrarenal aortic aneurysm treated with an intraluminal endovascular stent graft. 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{"pdf_hash": "8a9390c2ba639292170b0fe17bb53548e29bc768", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Measurements of keratocystic odontogenic tumor in the maxilla using axial computed tomographic images. A. The longest mesiodistal dimension of the cystic lesion is measured parallel to the coronal plane of the maxilla. B. The longest bucco-lingual dimension of the cystic lesion is measured parallel to the sagittal plane of the maxilla.", "width": 984, "height": 490, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "e95b0e23-6ad5-4cec-8290-2bb00528e4ca", "label": "a", "points": [[-0.2, 3.4], [-0.2, 488.4], [488, 488.4], [488, 3.4]], "color": "yellow"}, {"id": "6efd30ae-66b9-4dc7-9aa4-71b01a83a680", "label": "b", "points": [[500.4, 485.3], [500.4, 1.9], [980.7, 1.9], [980.7, 485.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Measurements", "start": 8, "end": 20, "id": 4}, {"text": "of", "start": 21, "end": 23, "id": 5}, {"text": "keratocystic", "start": 24, "end": 36, "id": 6}, {"text": "odontogenic", "start": 37, "end": 48, "id": 7}, {"text": "tumor", "start": 49, "end": 54, "id": 8}, {"text": "in", "start": 55, "end": 57, "id": 9}, {"text": "the", "start": 58, "end": 61, "id": 10}, {"text": "maxilla", "start": 62, "end": 69, "id": 11}, {"text": "using", "start": 70, "end": 75, "id": 12}, {"text": "axial", "start": 76, "end": 81, "id": 13}, {"text": "computed", "start": 82, "end": 90, "id": 14}, {"text": "tomographic", "start": 91, "end": 102, "id": 15}, {"text": "images", "start": 103, "end": 109, "id": 16}, {"text": ".", "start": 109, "end": 110, "id": 17}, {"text": "A.", "start": 111, "end": 113, "id": 18}, {"text": "The", "start": 114, "end": 117, "id": 19}, {"text": "longest", "start": 118, "end": 125, "id": 20}, {"text": "mesiodistal", "start": 126, "end": 137, "id": 21}, {"text": "dimension", "start": 138, "end": 147, "id": 22}, {"text": "of", "start": 148, "end": 150, "id": 23}, {"text": "the", "start": 151, "end": 154, "id": 24}, {"text": "cystic", "start": 155, "end": 161, "id": 25}, {"text": "lesion", "start": 162, "end": 168, "id": 26}, {"text": "is", "start": 169, "end": 171, "id": 27}, {"text": "measured", "start": 172, "end": 180, "id": 28}, {"text": "parallel", "start": 181, "end": 189, "id": 29}, {"text": "to", "start": 190, "end": 192, "id": 30}, {"text": "the", "start": 193, "end": 196, "id": 31}, {"text": "coronal", "start": 197, "end": 204, "id": 32}, {"text": "plane", "start": 205, "end": 210, "id": 33}, {"text": "of", "start": 211, "end": 213, "id": 34}, {"text": "the", "start": 214, "end": 217, "id": 35}, {"text": "maxilla", "start": 218, "end": 225, "id": 36}, {"text": ".", "start": 225, "end": 226, "id": 37}, {"text": "B.", "start": 227, "end": 229, "id": 38}, {"text": "The", "start": 230, "end": 233, "id": 39}, {"text": "longest", "start": 234, "end": 241, "id": 40}, {"text": "bucco", "start": 242, "end": 247, "id": 41}, {"text": "-", "start": 247, "end": 248, "id": 42}, {"text": "lingual", "start": 248, "end": 255, "id": 43}, {"text": "dimension", "start": 256, "end": 265, "id": 44}, {"text": "of", "start": 266, "end": 268, "id": 45}, {"text": "the", "start": 269, "end": 272, "id": 46}, {"text": "cystic", "start": 273, "end": 279, "id": 47}, {"text": "lesion", "start": 280, "end": 286, "id": 48}, {"text": "is", "start": 287, "end": 289, "id": 49}, {"text": "measured", "start": 290, "end": 298, "id": 50}, {"text": "parallel", "start": 299, "end": 307, "id": 51}, {"text": "to", "start": 308, "end": 310, "id": 52}, {"text": "the", "start": 311, "end": 314, "id": 53}, {"text": "sagittal", "start": 315, "end": 323, "id": 54}, {"text": "plane", "start": 324, "end": 329, "id": 55}, {"text": "of", "start": 330, "end": 332, "id": 56}, {"text": "the", "start": 333, "end": 336, "id": 57}, {"text": "maxilla", "start": 337, "end": 344, "id": 58}, {"text": ".", "start": 344, "end": 345, "id": 59}]}
{"pdf_hash": "9b56bc005f9cea5168a11903375f3adda1ca3be4", "fig_key": "Figure9", "fig_uri": "12-Figure9-1.png", "text": "FIG. 9. Bevacizumab induced pesudoresponse in a dog with a recurrent Grade III astrocytoma in the right parietal lobe following surgical resection. (A\u2013D) MR images of recurrent tumor prior to antiangiogenic therapy. An ovoid intraaxial mass adjacent to the previous craniectomy appears iso- to hypointense on transverse T1-weighted images (A), demonstrates heterogeneous ring enhancement on transverse (B) and sagittal (C) postcontrast T1-weighted images, and is heterogeneously hyperintense on transverse T2-weighted images (D). (E\u2013H) MR images corresponding to panels (A\u2013D), obtained 5 weeks after tumor biopsy and initiation of bevacizumab therapy. There is a reduction in the contrast-enhancing tumor (F, G), which would qualify as stable disease usingMacdonald and RECIST criteria. However, there is an increase in perilesional T2 hyperintensity extending into the adjacent white matter (H) associated with a falx shift and attenuation of the right lateral ventricle (E, F, H). (I) Transverse brain necropsy specimen, representing area depicted in panel H inset (H&E stain). 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{"pdf_hash": "0c05a168c104f104fcc1d4341c13e23ca9a169cd", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 \u2013 Computed tomography (CT) angiography of the 10 cm thoracic aortic aneurysm (An). A) Sagittal section. B) Oblique sagittal section at maximum diameter. C) Axial section at the level of the great vessels. D) Axial section at the level of the aortic arch.", "width": 672, "height": 662, "subcaptions": {"a": [21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "d": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "1adf60cb-ed6b-4467-804c-730cbaf4cacf", "label": "a", "points": [[2.4, 0.9], [2.4, 326.8], [282.7, 326.8], [282.7, 0.9]], "color": "yellow"}, {"id": "faa15037-3cc3-4c32-bbcb-178195abf16e", "label": "b", "points": [[1.4, 333.2], [1.4, 631.5], [285.9, 631.5], [285.9, 333.2]], "color": "cyan"}, {"id": "5386ad68-ca7f-4fb4-96b7-24d165d53d21", "label": "c", "points": [[292.2, 10.5], [292.2, 319.4], [671.2, 319.4], [671.2, 10.5]], "color": "magenta"}, {"id": "8a44e297-62dd-40da-8269-1f49b7d6be02", "label": "d", "points": [[297.5, 335.3], [297.5, 629.3], [671.2, 629.3], [671.2, 335.3]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "Computed", "start": 9, "end": 17, "id": 4}, {"text": "tomography", "start": 18, "end": 28, "id": 5}, {"text": "(", "start": 29, "end": 30, "id": 6}, {"text": "CT", "start": 30, "end": 32, "id": 7}, {"text": ")", "start": 32, "end": 33, "id": 8}, {"text": "angiography", "start": 34, "end": 45, "id": 9}, {"text": "of", "start": 46, "end": 48, "id": 10}, {"text": "the", "start": 49, "end": 52, "id": 11}, {"text": "10", "start": 53, "end": 55, "id": 12}, {"text": "cm", "start": 56, "end": 58, "id": 13}, {"text": "thoracic", "start": 59, "end": 67, "id": 14}, {"text": "aortic", "start": 68, "end": 74, "id": 15}, {"text": "aneurysm", "start": 75, "end": 83, "id": 16}, {"text": "(", "start": 84, "end": 85, "id": 17}, {"text": "An", "start": 85, "end": 87, "id": 18}, {"text": ")", "start": 87, "end": 88, "id": 19}, {"text": ".", "start": 88, "end": 89, "id": 20}, {"text": "A", "start": 90, "end": 91, "id": 21}, {"text": ")", "start": 91, "end": 92, "id": 22}, {"text": "Sagittal", "start": 93, "end": 101, "id": 23}, {"text": "section", "start": 102, "end": 109, "id": 24}, {"text": ".", "start": 109, "end": 110, "id": 25}, {"text": "B", "start": 111, "end": 112, "id": 26}, {"text": ")", "start": 112, "end": 113, "id": 27}, {"text": "Oblique", "start": 114, "end": 121, "id": 28}, {"text": "sagittal", "start": 122, "end": 130, "id": 29}, {"text": "section", "start": 131, "end": 138, "id": 30}, {"text": "at", "start": 139, "end": 141, "id": 31}, {"text": "maximum", "start": 142, "end": 149, "id": 32}, {"text": "diameter", "start": 150, "end": 158, "id": 33}, {"text": ".", "start": 158, "end": 159, "id": 34}, {"text": "C", "start": 160, "end": 161, "id": 35}, {"text": ")", "start": 161, "end": 162, "id": 36}, {"text": "Axial", "start": 163, "end": 168, "id": 37}, {"text": "section", "start": 169, "end": 176, "id": 38}, {"text": "at", "start": 177, "end": 179, "id": 39}, {"text": "the", "start": 180, "end": 183, "id": 40}, {"text": "level", "start": 184, "end": 189, "id": 41}, {"text": "of", "start": 190, "end": 192, "id": 42}, {"text": "the", "start": 193, "end": 196, "id": 43}, {"text": "great", "start": 197, "end": 202, "id": 44}, {"text": "vessels", "start": 203, "end": 210, "id": 45}, {"text": ".", "start": 210, "end": 211, "id": 46}, {"text": "D", "start": 212, "end": 213, "id": 47}, {"text": ")", "start": 213, "end": 214, "id": 48}, {"text": "Axial", "start": 215, "end": 220, "id": 49}, {"text": "section", "start": 221, "end": 228, "id": 50}, {"text": "at", "start": 229, "end": 231, "id": 51}, {"text": "the", "start": 232, "end": 235, "id": 52}, {"text": "level", "start": 236, "end": 241, "id": 53}, {"text": "of", "start": 242, "end": 244, "id": 54}, {"text": "the", "start": 245, "end": 248, "id": 55}, {"text": "aortic", "start": 249, "end": 255, "id": 56}, {"text": "arch", "start": 256, "end": 260, "id": 57}, {"text": ".", "start": 260, "end": 261, "id": 58}]}
{"pdf_hash": "a12735d06ed86921031c7cd421355b43568dcb8e", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Grayscale image. (A) Preoperative T2-weighted sagittal magnetic resonance image of a 58-year-old male, showing spinal cord compressions at C4\u2013C7. Sagittal alignment shows segmental apical kyphosis with overall lordosis. (B) Postoperative magnetic resonance image of the same patient taken four months after laminectomy, demonstrating successful decompression of the spinal cord. The magnitude of postoperative backward shifting of the spinal cord was 1.5 mm. 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{"pdf_hash": "9619a23634c544aa5a2acf63c487017c165a0e3b", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Retrograde tracer injection sites. Representative serial sections showing sites of retrograde tracer injection into the BLA are shown in (A--C). Schematic sections showing maximal diffusion of tracer are shown in (D--F).", "width": 998, "height": 902, "subcaptions": {"a": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "32b018c8-3aa9-4a03-9744-1d6881f54654", "label": "a", "points": [[344.5, 442.8], [344.5, -0.3], [0.8, -0.3], [0.8, 442.8]], "color": "yellow"}, {"id": "cf515c22-9e11-4c20-852f-1cf3ff8615e3", "label": "a", "points": [[354, 2.9], [354, 445.9], [664.6, 445.9], [664.6, 2.9]], "color": "cyan"}, {"id": "273d01ce-f78b-420d-8b29-737d85c25409", "label": "a", "points": [[675.6, 2.9], [675.6, 447.5], [992.5, 447.5], [992.5, 2.9]], "color": "magenta"}, {"id": "21d6e8cc-82ea-47a2-96d3-13623e979614", "label": "b", "points": [[4, 455.4], [4, 900], [316.2, 900], [316.2, 455.4]], "color": "springgreen"}, {"id": "521ad3d5-bfb3-427b-89c3-08539813e92d", "label": "b", "points": [[327.2, 455.4], [327.2, 896.8], [659.9, 896.8], [659.9, 455.4]], "color": "tomato"}, {"id": "81f8f83f-0265-4585-a490-df4531581556", "label": "b", "points": [[675.6, 455.4], [675.6, 893.6], [994.1, 893.6], [994.1, 455.4]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Retrograde", "start": 10, "end": 20, "id": 3}, {"text": "tracer", "start": 21, "end": 27, "id": 4}, {"text": "injection", "start": 28, "end": 37, "id": 5}, {"text": "sites", "start": 38, "end": 43, "id": 6}, {"text": ".", "start": 43, "end": 44, "id": 7}, {"text": "Representative", "start": 45, "end": 59, "id": 8}, {"text": "serial", "start": 60, "end": 66, "id": 9}, {"text": "sections", "start": 67, "end": 75, "id": 10}, {"text": "showing", "start": 76, "end": 83, "id": 11}, {"text": "sites", "start": 84, "end": 89, "id": 12}, {"text": "of", "start": 90, "end": 92, "id": 13}, {"text": "retrograde", "start": 93, "end": 103, "id": 14}, {"text": "tracer", "start": 104, "end": 110, "id": 15}, {"text": "injection", "start": 111, "end": 120, "id": 16}, {"text": "into", "start": 121, "end": 125, "id": 17}, {"text": "the", "start": 126, "end": 129, "id": 18}, {"text": "BLA", "start": 130, "end": 133, "id": 19}, {"text": "are", "start": 134, "end": 137, "id": 20}, {"text": "shown", "start": 138, "end": 143, "id": 21}, {"text": "in", "start": 144, "end": 146, "id": 22}, {"text": "(", "start": 147, "end": 148, "id": 23}, {"text": "A", "start": 148, "end": 149, "id": 24}, {"text": "--", "start": 149, "end": 151, "id": 25}, {"text": "C", "start": 151, "end": 152, "id": 26}, {"text": ")", "start": 152, "end": 153, "id": 27}, {"text": ".", "start": 153, "end": 154, "id": 28}, {"text": "Schematic", "start": 155, "end": 164, "id": 29}, {"text": "sections", "start": 165, "end": 173, "id": 30}, {"text": "showing", "start": 174, "end": 181, "id": 31}, {"text": "maximal", "start": 182, "end": 189, "id": 32}, {"text": "diffusion", "start": 190, "end": 199, "id": 33}, {"text": "of", "start": 200, "end": 202, "id": 34}, {"text": "tracer", "start": 203, "end": 209, "id": 35}, {"text": "are", "start": 210, "end": 213, "id": 36}, {"text": "shown", "start": 214, "end": 219, "id": 37}, {"text": "in", "start": 220, "end": 222, "id": 38}, {"text": "(", "start": 223, "end": 224, "id": 39}, {"text": "D", "start": 224, "end": 225, "id": 40}, {"text": "--", "start": 225, "end": 227, "id": 41}, {"text": "F", "start": 227, "end": 228, "id": 42}, {"text": ")", "start": 228, "end": 229, "id": 43}, {"text": ".", "start": 229, "end": 230, "id": 44}]}
{"pdf_hash": "cedff71f49a5ac4a4c9664472b479011a94bdca3", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Cerebral magnetic resonance imaging of our patient performed at \u03f37.5 months of age (corrected age of 5 months). A: Sagittal T1-weighted image. B: axial T1-weighted image. C: axial T2-weighted image. Note the presence of bilateral periventricular nodular heterotopia (arrows), as well as widening of subarachnoidal spaces.", "width": 1364, "height": 468, "subcaptions": {"a": [25, 26, 27, 28, 29, 30], "b": [31, 32, 33, 34, 35, 36], "c": [37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "44ee5016-3db7-4ca9-92bc-61745690e68c", "label": "a", "points": [[19.4, 4.3], [19.4, 443.9], [452.5, 443.9], [452.5, 4.3]], "color": "yellow"}, {"id": "8f8b23d5-18e4-4df9-bed5-4eb53c6c6101", "label": "b", "points": [[459, 443.9], [459, 0], [889.9, 0], [889.9, 443.9]], "color": "cyan"}, {"id": "695d8187-31fe-4605-a707-99d5062d5a0c", "label": "c", "points": [[896.4, 2.2], [896.4, 437.4], [1342.5, 437.4], [1342.5, 2.2]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Cerebral", "start": 8, "end": 16, "id": 4}, {"text": "magnetic", "start": 17, "end": 25, "id": 5}, {"text": "resonance", "start": 26, "end": 35, "id": 6}, {"text": "imaging", "start": 36, "end": 43, "id": 7}, {"text": "of", "start": 44, "end": 46, "id": 8}, {"text": "our", "start": 47, "end": 50, "id": 9}, {"text": "patient", "start": 51, "end": 58, "id": 10}, {"text": "performed", "start": 59, "end": 68, "id": 11}, {"text": "at", "start": 69, "end": 71, "id": 12}, {"text": "\u03f37.5", "start": 72, "end": 76, "id": 13}, {"text": "months", "start": 77, "end": 83, "id": 14}, {"text": "of", "start": 84, "end": 86, "id": 15}, {"text": "age", "start": 87, "end": 90, "id": 16}, {"text": "(", "start": 91, "end": 92, "id": 17}, {"text": "corrected", "start": 92, "end": 101, "id": 18}, {"text": "age", "start": 102, "end": 105, "id": 19}, {"text": "of", "start": 106, "end": 108, "id": 20}, {"text": "5", "start": 109, "end": 110, "id": 21}, {"text": "months", "start": 111, "end": 117, "id": 22}, {"text": ")", "start": 117, "end": 118, "id": 23}, {"text": ".", "start": 118, "end": 119, "id": 24}, {"text": "A", "start": 120, "end": 121, "id": 25}, {"text": ":", "start": 121, "end": 122, "id": 26}, {"text": "Sagittal", "start": 123, "end": 131, "id": 27}, {"text": "T1-weighted", "start": 132, "end": 143, "id": 28}, {"text": "image", "start": 144, "end": 149, "id": 29}, {"text": ".", "start": 149, "end": 150, "id": 30}, {"text": "B", "start": 151, "end": 152, "id": 31}, {"text": ":", "start": 152, "end": 153, "id": 32}, {"text": "axial", "start": 154, "end": 159, "id": 33}, {"text": "T1-weighted", "start": 160, "end": 171, "id": 34}, {"text": "image", "start": 172, "end": 177, "id": 35}, {"text": ".", "start": 177, "end": 178, "id": 36}, {"text": "C", "start": 179, "end": 180, "id": 37}, {"text": ":", "start": 180, "end": 181, "id": 38}, {"text": "axial", "start": 182, "end": 187, "id": 39}, {"text": "T2-weighted", "start": 188, "end": 199, "id": 40}, {"text": "image", "start": 200, "end": 205, "id": 41}, {"text": ".", "start": 205, "end": 206, "id": 42}, {"text": "Note", "start": 207, "end": 211, "id": 43}, {"text": "the", "start": 212, "end": 215, "id": 44}, {"text": "presence", "start": 216, "end": 224, "id": 45}, {"text": "of", "start": 225, "end": 227, "id": 46}, {"text": "bilateral", "start": 228, "end": 237, "id": 47}, {"text": "periventricular", "start": 238, "end": 253, "id": 48}, {"text": "nodular", "start": 254, "end": 261, "id": 49}, {"text": "heterotopia", "start": 262, "end": 273, "id": 50}, {"text": "(", "start": 274, "end": 275, "id": 51}, {"text": "arrows", "start": 275, "end": 281, "id": 52}, {"text": ")", "start": 281, "end": 282, "id": 53}, {"text": ",", "start": 282, "end": 283, "id": 54}, {"text": "as", "start": 284, "end": 286, "id": 55}, {"text": "well", "start": 287, "end": 291, "id": 56}, {"text": "as", "start": 292, "end": 294, "id": 57}, {"text": "widening", "start": 295, "end": 303, "id": 58}, {"text": "of", "start": 304, "end": 306, "id": 59}, {"text": "subarachnoidal", "start": 307, "end": 321, "id": 60}, {"text": "spaces", "start": 322, "end": 328, "id": 61}, {"text": ".", "start": 328, "end": 329, "id": 62}]}
{"pdf_hash": "3631e45e681b98ffa5353ff5210335482df456cf", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2: (a) Unenhanced CT (7.50 am) showing hyperdense thrombus in the basilar trunk without parenchymal infarcts (arrow); (b, c, d) MRI brain ADC map with time of flight MRA sequences revealing midbrain and bilateral thalamic infarcts and distal basilar thrombus (9.05 am); (e, f) Magnetic resonance angiogram showing occlusion of basilar top with preserved flow into both superior cerebellar arteries (10.10 am); (g, h) Magnetic resonance angiogram obtained four weeks later showing recanalized basilar top with good flow into the posterior cerebral arteries", "width": 1392, "height": 1794, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107]}, "subfigures": [{"id": "a3e7d21e-2974-45fa-bf47-74ad30ad9953", 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{"pdf_hash": "34eb52e467f13ac3e9ad7049e0656fe648624f6f", "fig_key": "Figure6", "fig_uri": "10-Figure6-1.png", "text": "Fig. 6. MRE images demonstrate heterogeneous distribution of stiffness in kidney. A, B. Images from 49-year-old man with poor allograft function 12 years after transplantation (eGFR = 15 mL/min/1.73 m2). C, D. Images from 32-year-old man with good functioning allograft 4 years after transplantation (eGFR = 89 mL/min/1.73 m2). A, C. Anatomic T2 weighted images of kidney allografts; B, D MRE stiffness maps, where blue color represents softer tissue and red represents stiffer tissue. 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{"pdf_hash": "392159b6b76e7ddbfe3c0c5eeadc8983ff1cd2bf", "fig_key": "Figure7", "fig_uri": "8-Figure7-1.png", "text": "FIG. 7. The graft receives relatively sparse input from the host POA. A, Low power brightfield photomicrograph showing an injection (asterisk) of the anterograde tracer, PHA-L, located in the host POA adjacent to a SCN graft (g). The boxed area in A is shown in B at higher magnification. Labeled fibers course around the graft to innervate the contralateral host POA, but relatively few fibers actually enter the graft (arrows). ac, Anterior commissure. 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{"pdf_hash": "b7c7294928649b657fc9e35c0fedfd61fd36c49c", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. \u2013 Case 2. a) Computed tomography (CT) scan without contrast media, mediastinal windows, shows an oval mass with homogeneous high density (65 UH), peripheral calcification, and a right small pleural effusion. b) CT scan with contrast media, mediastinal windows, shows a ring enhancement which is probably related to mediastinal pleura inflammation. c) Sagittal spin echo T1-weighted image shows the medistinal mass with a high signal intensity and its anatomical relations. d) Axial spin echo T2-weighted image also shows a high signal intensity of the mass (like cerebrospinal fluid) and a pleural effusion.", "width": 668, "height": 858, "subcaptions": {"a": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69], "b": [91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 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{"pdf_hash": "abafda18986608c51a13f5e30815195c881c2482", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1: A 56-year-old male involved in a motor vehicle accident. 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{"pdf_hash": "07a8ad329b9a5cbb2246fd01a9c6f1b9b8c6086e", "fig_key": "Figure5", "fig_uri": "10-Figure5-1.png", "text": "FIGURE 5 ESI mass-density measurements of the subnuclear compartments. (A) ESI of an Sk-N-SH neuroblastoma cell nucleus. The image was recorded at 120 eV energy loss. Sample preparation involved fixation in 2% paraformaldehyde for 30 min, followed by fixation in 0.5% glutaraldehyde overnight. Cells were dehydrated in ethanol and embedded in Qetol resin. Then 70-nm sections were picked up on 400-mesh electron microscopy grids, which were subsequently covered with a 3-nm carbon film picked up from the surface of water. The ratio (nucleolus divided by nucleoplasm) of the average intensity values of the two regions indicated is 1.93. (B) Bright-field image of a macrophage cell (RAW) cryopreserved by slam-freezing. The frozen hydrated sections were picked up onto a copper grid coated with a 3-nm carbon film. The grid was transferred to the electron microscope at liquid nitrogen temperature. The section was freeze-dried in the microscope column before imaging. The removal of water and the absence of a resin embedding material allow for very high contrast without the need for heavy atom contrast agents. The images, therefore, provide mass-density information. The ratio (nucleolus divided by nucleoplasm) of the average intensity values of the two regions indicated is 1.32. (C) Low-magnification mass-sensitive image of an Sk-N-SH cell recorded at 120 eV. (D) Net phosphorus image of a field from the nucleus presented in C. The arrows in C and D provide a fiduciary for each image and indicate the slight rotation between the images recorded at different magnifications. (E) The net phosphorus image was subtracted from the net nitrogen image (the resulting signal was represented in shades of blue). The net phosphorus signal (yellow) was superimposed on the nitrogenphosphorus signal. GC, DFC and Ch represent granular component, dense fibrillar component, and chromatin, respectively. (F) High magnification of a field in E. Chromatin fibers can be visualized in the nucleoplasm, bordering the nucleolus, and within the nucleolus (referred to as NuChromatin in G). (G) Identification of different regions and structures associated with nucleolus. 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{"pdf_hash": "551dc0ca9366e31d1e30ef4bb567876fd6758639", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Type 1A herniation: (a) T2 image with L4-5 LDH, (b) 3D FSPGR image, (c, d) CT scan images, (e) sketch of the 3D FSPGR. Black arrow\u2014bony irregularity at posterior superior corner of L5. 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{"pdf_hash": "1773cede01d5b99e95fe3b7e2cc19559f10d8c01", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Ray-tracing dynamics illustrating the different response of integrable geometries, panels (a,b), and non-integrable chaotic geometries, panels (c,d). Panels (a) shows initial ray trajectories in the transverse section of an integrable geometry corresponding to an idealized multi-mode fibers having perfect circular symmetry. Panel (b) shows the regular whispering-gallery like pattern that results after propagating the initial rays in panel (a) for a long time (> 10 3 round trips). Panel (c) shows corresponding results for a non-integrable chaotic geometry including a circular scatterer. Note that the ray pattern results from the same initial conditions as for panel (b). 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{"pdf_hash": "8ed17a11ad9651ec8b5a1b9f59b1aa955aeb7ee8", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. A, CT angiography image showing a large aneurysm in the distal portion of the right coronary artery. The proximal portion is intact. AA = ascending aorta, DA = descending aorta, RCA = right coronary artery, A = aneurysm; B, coronary artery angiography image showing a huge right coronary artery aneurysm. The proximal portion of the right coronary artery is intact. 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{"pdf_hash": "cc3d57075cf8362897501d749b3a2faa72e6f943", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (a) Preoperative extraoral photograph showing mandibular prognathism. (b and c) Postsurgical photograph after bilateral sagittal split osteotomy and genioplasty", "width": 470, "height": 508, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12], "b": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26]}, "subfigures": [{"id": "d23051da-0342-4f56-b3f0-8df53f4e13ec", "label": "a", "points": [[37.8, 0.9], [37.8, 235.9], [223.8, 235.9], [223.8, 0.9]], "color": "yellow"}, {"id": "ab925b1d-fdb4-461f-950a-01e217d0a100", "label": "b", "points": [[229.8, 4.9], [229.8, 241.9], [460.8, 241.9], [460.8, 4.9]], "color": "cyan"}, {"id": "d5f27cfc-f49e-408e-95de-ae663729c4f4", "label": "b", "points": [[132.8, 241.9], [132.8, 475.9], [364.8, 475.9], [364.8, 241.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Preoperative", "start": 14, "end": 26, "id": 6}, {"text": "extraoral", "start": 27, "end": 36, "id": 7}, {"text": "photograph", "start": 37, "end": 47, "id": 8}, {"text": "showing", "start": 48, "end": 55, "id": 9}, {"text": "mandibular", "start": 56, "end": 66, "id": 10}, {"text": "prognathism", "start": 67, "end": 78, "id": 11}, {"text": ".", "start": 78, "end": 79, "id": 12}, {"text": "(", "start": 80, "end": 81, "id": 13}, {"text": "b", "start": 81, "end": 82, "id": 14}, {"text": "and", "start": 83, "end": 86, "id": 15}, {"text": "c", "start": 87, "end": 88, "id": 16}, {"text": ")", "start": 88, "end": 89, "id": 17}, {"text": "Postsurgical", "start": 90, "end": 102, "id": 18}, {"text": "photograph", "start": 103, "end": 113, "id": 19}, {"text": "after", "start": 114, "end": 119, "id": 20}, {"text": "bilateral", "start": 120, "end": 129, "id": 21}, {"text": "sagittal", "start": 130, "end": 138, "id": 22}, {"text": "split", "start": 139, "end": 144, "id": 23}, {"text": "osteotomy", "start": 145, "end": 154, "id": 24}, {"text": "and", "start": 155, "end": 158, "id": 25}, {"text": "genioplasty", "start": 159, "end": 170, "id": 26}]}
{"pdf_hash": "30d121d90b932f0748a1e9602315ca974530bf7b", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Illustrative case of patient No. 6, a 71-year-old man with history of colon cancer. A sagittal T1 weighted MRI of cervical spine shows an extradural compression of the spinal cord from the lower border of C2\u2013C4 (a). The axial computed tomography of cervical spine demonstrates the destruction of the pedicle and foramen transversarium (b). The postoperative lateral plain X-rays show the instrumentation from C1 to C7, the corpectomy of C3 with anterior reconstruction with a titanium cage between C2\u2013C4 (c)", "width": 1000, "height": 456, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67], "c": [68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98]}, "subfigures": [{"id": "88169c1a-689d-40c7-92da-d8cf88f73914", "label": "a", "points": [[250.4, 454.7], [250.4, 1.3], [2.4, 1.3], [2.4, 454.7]], "color": "yellow"}, {"id": "46113f3c-eac9-472d-8502-be4581930ba0", "label": "b", "points": [[266.2, 4.5], [266.2, 450], [526.9, 450], [526.9, 4.5]], "color": "cyan"}, {"id": "d70afe35-5c65-4b8f-9cab-629a78936376", "label": "c", "points": [[544.3, -0.3], [544.3, 453.1], [988.2, 453.1], [988.2, -0.3]], 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{"pdf_hash": "e0dcdddc7d50a940ccb3cb43011f1f51949edac0", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. The neuron loss in visual cortex after prenatal ethanol exposure. (A\u2013C) P14 visual cortices (coronal section with H.E. staining) of different treatments were displayed in low magnification. The cortical plate became thin after prenatal ethanol exposure, with dose-dependency. (D\u2013F) pyramidal cells in visual cortex (P14) were stained with Nissl staining. The dose-dependent neuron loss is obvious after ethanol exposure. Control (cont), moderate dose (mode) and high dose (high) are marked in the photos. Bar = 120 \u00b5m in (A\u2013C), and bar = 30 \u00b5m in (D\u2013F).", "width": 1052, "height": 516, "subcaptions": {"a": [15, 16, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 85, 86, 87, 88], "b": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 90, 91, 92, 93, 94], "c": [15, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 96, 97, 98, 99, 100], "d": [54, 55, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88], "e": [54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 90, 91, 92, 93, 94], "f": [54, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 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{"pdf_hash": "1b25118fcbac8df134308a81b9af36d2ca0a07c2", "fig_key": "Figure8", "fig_uri": "6-Figure8-1.png", "text": "Figure 8 Ultrasound (a) and histology (b) of the same case showing a thickness difference of less than 1 mm (0.7 mm) between the methods and corresponding to a patient with a tumor measuring 4.2 mm thick by ultrasound and 3.5 mm by histology. Calipers are marking the lateral extension of the lesion, not the depth. Note the similar shape of the tumor under ultrasound and under 2 \u00c2 zoom hematoxylin/eosin stain in histology.", "width": 1022, "height": 328, "subcaptions": {"a": [2, 3, 4, 5, 39, 40, 41, 42, 43, 44], "b": [39, 8, 9, 10, 7, 46, 47, 48, 49]}, "subfigures": [{"id": "4596707e-c53d-478b-ba7b-56a735414268", "label": "a", "points": [[36.4, 6.2], [36.4, 322.6], [485.2, 322.6], [485.2, 6.2]], "color": "yellow"}, {"id": "1bd4eaf0-3e39-468e-aa75-f8fb4b9f3173", "label": "b", "points": [[551.4, 6.2], [551.4, 325.9], [1016.4, 325.9], [1016.4, 6.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "8", "start": 7, "end": 8, "id": 1}, {"text": "Ultrasound", "start": 9, "end": 19, "id": 2}, {"text": "(", "start": 20, "end": 21, "id": 3}, {"text": "a", "start": 21, "end": 22, "id": 4}, {"text": ")", "start": 22, "end": 23, "id": 5}, {"text": "and", "start": 24, "end": 27, "id": 6}, {"text": "histology", "start": 28, "end": 37, "id": 7}, {"text": "(", 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{"pdf_hash": "e94a39a0ee71628136a59614861984b11af237fe", "fig_key": "Figure8", "fig_uri": "8-Figure8-1.png", "text": "Figure 8. Comparative imaging of high (SKOV3) and low (A431) HER2-expressing xenografts in mice. Micro-single photon emission computed tomography/computed tomography imaging of human epidermal growth factor receptor 2 expression in BALB/C nu/nu mice bearing (A) SKOV3 and (B) A431 xenografts at 4 h post-injection using [ 125 I]I-G3-H 6 . The uptake of radiocatabolites by Na/I-symporters was blocked by addition of KI in drinking water. S, stomach; K, kidneys; T, tumor.", "width": 678, "height": 622, "subcaptions": {"a": [48, 49, 50, 51], "b": [53, 54, 55, 56]}, "subfigures": [{"id": "26336b7e-d6ee-48e6-a103-7a13a253d672", "label": "a", "points": [[19.9, 4.1], [19.9, 580.3], [321.9, 580.3], [321.9, 4.1]], "color": "yellow"}, {"id": "5c383965-50d8-4f86-898d-5efe1233183d", "label": "b", "points": [[326.2, 4.1], [326.2, 579.2], [650.7, 579.2], [650.7, 4.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "8", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Comparative", "start": 10, "end": 21, "id": 3}, {"text": "imaging", "start": 22, "end": 29, "id": 4}, {"text": "of", "start": 30, "end": 32, "id": 5}, {"text": "high", "start": 33, "end": 37, "id": 6}, {"text": "(", "start": 38, "end": 39, "id": 7}, {"text": "SKOV3", "start": 39, "end": 44, "id": 8}, {"text": ")", "start": 44, "end": 45, "id": 9}, {"text": "and", "start": 46, "end": 49, 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{"pdf_hash": "fc32531a4fe259634c948e3fc0fc37b6b48d80df", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Findings on contrast-enhanced abdominal computed tomography. A: Sagittal section demonstrates thickened loops of small bowel (arrow); B: Coronal image demonstrates free peritoneal fluid (arrow), thickened loops of small bowel and circumferential mural thickening of the distal stomach (heavy arrow).", "width": 858, "height": 394, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "188494b0-b39e-49d6-8e63-5d2d17cb8f1c", "label": "a", "points": [[3.4, 3.2], [3.4, 390.8], [509, 390.8], [509, 3.2]], "color": "yellow"}, {"id": "bca4e187-3966-4a4a-a4c2-a10e38253275", "label": "b", "points": [[521.2, 3.2], [521.2, 390.8], [854.6, 390.8], [854.6, 3.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Findings", "start": 9, "end": 17, "id": 2}, {"text": "on", "start": 18, "end": 20, "id": 3}, {"text": "contrast", "start": 21, "end": 29, "id": 4}, {"text": "-", "start": 29, "end": 30, "id": 5}, {"text": "enhanced", "start": 30, "end": 38, "id": 6}, {"text": "abdominal", "start": 39, "end": 48, "id": 7}, {"text": "computed", "start": 49, "end": 57, "id": 8}, {"text": "tomography", "start": 58, "end": 68, "id": 9}, {"text": ".", "start": 68, "end": 69, "id": 10}, {"text": "A", "start": 70, "end": 71, "id": 11}, {"text": ":", "start": 71, "end": 72, "id": 12}, {"text": "Sagittal", "start": 73, "end": 81, "id": 13}, {"text": "section", "start": 82, "end": 89, "id": 14}, {"text": "demonstrates", "start": 90, "end": 102, "id": 15}, {"text": "thickened", "start": 103, "end": 112, "id": 16}, {"text": "loops", "start": 113, "end": 118, "id": 17}, {"text": "of", "start": 119, "end": 121, "id": 18}, {"text": "small", "start": 122, "end": 127, "id": 19}, {"text": "bowel", "start": 128, "end": 133, "id": 20}, {"text": "(", "start": 134, "end": 135, "id": 21}, {"text": "arrow", "start": 135, "end": 140, "id": 22}, {"text": ")", "start": 140, "end": 141, "id": 23}, {"text": ";", "start": 141, "end": 142, "id": 24}, {"text": "B", "start": 143, "end": 144, "id": 25}, {"text": ":", "start": 144, "end": 145, "id": 26}, {"text": "Coronal", "start": 146, "end": 153, "id": 27}, {"text": "image", "start": 154, "end": 159, "id": 28}, {"text": "demonstrates", "start": 160, "end": 172, "id": 29}, {"text": "free", "start": 173, "end": 177, "id": 30}, {"text": "peritoneal", "start": 178, "end": 188, "id": 31}, {"text": "fluid", "start": 189, "end": 194, "id": 32}, {"text": "(", "start": 195, "end": 196, "id": 33}, {"text": "arrow", "start": 196, "end": 201, "id": 34}, {"text": ")", "start": 201, "end": 202, "id": 35}, {"text": ",", "start": 202, "end": 203, "id": 36}, {"text": "thickened", "start": 204, "end": 213, "id": 37}, {"text": "loops", "start": 214, "end": 219, "id": 38}, {"text": "of", "start": 220, "end": 222, "id": 39}, {"text": "small", "start": 223, "end": 228, "id": 40}, {"text": "bowel", "start": 229, "end": 234, "id": 41}, {"text": "and", "start": 235, "end": 238, "id": 42}, {"text": "circumferential", "start": 239, "end": 254, "id": 43}, {"text": "mural", "start": 255, "end": 260, "id": 44}, {"text": "thickening", "start": 261, "end": 271, "id": 45}, {"text": "of", "start": 272, "end": 274, "id": 46}, {"text": "the", "start": 275, "end": 278, "id": 47}, {"text": "distal", "start": 279, "end": 285, "id": 48}, {"text": "stomach", "start": 286, "end": 293, "id": 49}, {"text": "(", "start": 294, "end": 295, "id": 50}, {"text": "heavy", "start": 295, "end": 300, "id": 51}, {"text": "arrow", "start": 301, "end": 306, "id": 52}, {"text": ")", "start": 306, "end": 307, "id": 53}, {"text": ".", "start": 307, "end": 308, "id": 54}]}
{"pdf_hash": "5528dc6a7e802dad5cb75bbe6a8f9286ba451947", "fig_key": "Figure7", "fig_uri": "6-Figure7-1.png", "text": "Fig. 7 In a 77-year-old female with recurrent upper abdominal pain, axial (a) and coronal (b) post-contrast CT images showed a duodenal diverticulum (arrows) filled by air and enteral material, in typical medial site at distal descending duodenum. 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{"pdf_hash": "dc2455ae6075f7ff8588bdd68abe926ab01b71e2", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. CT scan (sagital and coronal views): nodular thickening and enhancement of the peritoneum. Peritoneal effusion is also present.", "width": 472, "height": 982, "subcaptions": {"a": [0]}, "subfigures": [{"id": "a014dde0-702d-43d9-8b57-e4e35e575025", "label": "a", "points": [[5.8, 1.9], [5.8, 433.9], [469.8, 433.9], [469.8, 1.9]], "color": "yellow"}, {"id": "c3bfb3ff-55e9-4fd9-8807-ec537afa290f", "label": "b", "points": [[2.8, 448.9], [2.8, 979.9], [470.8, 979.9], [470.8, 448.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "scan", "start": 13, "end": 17, "id": 4}, {"text": "(", "start": 18, "end": 19, "id": 5}, {"text": "sagital", "start": 19, "end": 26, "id": 6}, {"text": "and", "start": 27, "end": 30, "id": 7}, {"text": "coronal", "start": 31, "end": 38, "id": 8}, {"text": "views", "start": 39, "end": 44, "id": 9}, {"text": ")", "start": 44, "end": 45, "id": 10}, {"text": ":", "start": 45, "end": 46, "id": 11}, {"text": "nodular", "start": 47, "end": 54, "id": 12}, {"text": "thickening", "start": 55, "end": 65, "id": 13}, {"text": "and", "start": 66, "end": 69, "id": 14}, {"text": "enhancement", "start": 70, "end": 81, "id": 15}, {"text": "of", "start": 82, "end": 84, "id": 16}, {"text": "the", "start": 85, "end": 88, "id": 17}, {"text": "peritoneum", "start": 89, "end": 99, "id": 18}, {"text": ".", "start": 99, "end": 100, "id": 19}, {"text": "Peritoneal", "start": 101, "end": 111, "id": 20}, {"text": "effusion", "start": 112, "end": 120, "id": 21}, {"text": "is", "start": 121, "end": 123, "id": 22}, {"text": "also", "start": 124, "end": 128, "id": 23}, {"text": "present", "start": 129, "end": 136, "id": 24}, {"text": ".", "start": 136, "end": 137, "id": 25}]}
{"pdf_hash": "8e157676153fa16a726d6cae27ae7cf961f6c33c", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Figure 6. Comparison of proposed PPADS and TNP-ATP binding modes. a, proposed PPADS binding mode for P2X1R. b, for comparison the X-ray structure of chicken P2X7 receptor with TNP-ATP bound is shown. Equivalent lysine residues involved in salt bridges to sulfonate groups of PPADS (a) and phosphate groups of TNP-ATP are labeled. c, visualization of electrostatic potential for the P2X1R model used in a. The electrostatic potential was calculated using the Protein Data Bank 2PQR. d, as in c, but PPADS was omitted.", "width": 1000, "height": 830, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21], "b": [68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92], "c": [96, 97, 98, 99, 100, 101, 102, 103, 93, 94, 95], "d": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67]}, "subfigures": [{"id": "7be56993-dc5c-491c-ab74-015f43d2ec03", "label": "a", "points": [[33.2, 1.6], [33.2, 376], [485, 376], [485, 1.6]], "color": "yellow"}, {"id": "f65300c8-e7f9-47d1-8643-cb1171742063", "label": "d", "points": [[511.9, 376], [511.9, 1.6], [968.4, 1.6], [968.4, 376]], "color": "cyan"}, {"id": "6c2ca041-2929-498b-be4a-f2d76ed31416", "label": "b", "points": [[39.5, 420.2], [39.5, 794.7], [488.2, 794.7], [488.2, 420.2]], 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{"pdf_hash": "04bf6c8d2d2a7cd0d763e53595774e39e22c825c", "fig_key": "Figure20", "fig_uri": "13-Figure20-1.png", "text": "Figure 20: An 84-year-old patient with a known history of metastatic prostate cancer and of LS presents with recurrent episodes of left ischemic colitis confirmed by optical colonoscopy. Sagital (a) and coronal (b) MPR views show complete thrombosis of the aorta just under the emergence of the RAs (blue arrows). Axial views (c, d, e) show typical thickening and hypodensity of the colonic wall (white circle). 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{"pdf_hash": "385818e43b3236cb149d3ba0cc28f74d42a81a40", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2: Ultrastructural effects of SPZ on T. gondii tachyzoites as visualized by TEM. TEM pictures were prepared with untreated tachyzoites from the PBS-cultured groups (a1 and a2) and with tachyzoites treated for 2 h with an SPZ solution (b1 and b2). Abbreviations: C, conoid; CM, cell membrane; DG, dense granule; Go, golgi complex; LP, lipid body; Mc, mitochondrion; MN, microneme; N, nucleus; NM, nuclear membrane; RH, rhoptry; I, inner layer; O, outer layer Discussion Electron microscope has been widely used in the classification and identification of parasites, and in exploring the effects and mechanisms of drug action by observing the effects of the drug on parasite ultrastructure. Dubremetz et al. (2009) used ultrastructural techniques to classify previously unrelated parasites within a single phylum, the Apicomplexa (17). Stettler et al. 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{"pdf_hash": "fe2ce34c3aff3e158b46d492811b48165cd93128", "fig_key": "Figure5", "fig_uri": "19-Figure5-1.png", "text": "Figure 5. Autoradiography and immunohistochemistry demonstrate [ 18 F]AH113804 retention in c-Met positive HCC1954 tumor tissue. (A) Autoradiography performed ex vivo on a resected tumor confirms retention of the [ 18 F]AH113804 radiotracer in tumor tissues. A heterogeneous distribution of tracer within the tumor section could be observed, not visible at the limited spatial resolution of PET imaging. (B) H&E staining (upper) and cMet immunostaining (lower) of paraffin-embedded tumor and control skeletal muscle tissue (left and right columns respectively). H&E staining reveals the large, mitotic and disorganized phenotype characteristic of tumor cells, while immunohistochemistry reveals membranous c-Met staining in these cells. 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{"pdf_hash": "9fc89d9f4d32177795827d0b5a976c8aea2cf817", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Axial head computed tomography (CT) scans on admission showing a subdural hematoma in the right frontal and occipital interhemispheric fissure (A) and in the occipital fossa (D). Preoperative coronal T 1 -weighted magnetic resonance image with gadolinium showing a subdural hematoma compressing the right motor cortex in the right frontal interhemispheric fissure (B). 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{"pdf_hash": "bc99a06ad215bd968ecce508a9649b348f83062d", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Figure 3. Statistical parametric maps (SPMs) of the group analysis (4 young and 4 elderly healthy male volunteers, 3 functional magnetic resonance imaging [fMRI] exams per subject) during \u201cn-back\u201d spatial working memory task versus control. In the control condition (\u201c0-back\u201d), subjects had to respond when a square appeared in a given position on the computer screen; in the \u201c1-back\u201d condition, when it appeared in the same place as 1 screen before; in the \u201c2-back\u201d condition when it appeared in the same place as 2 screens before. In both the 1-back and the 2-back tasks, accuracy score was similar in elderly and young subjects. Reaction time was similar in the two groups during the 1-back task, but significantly longer in the elderly group during the 2-back task. 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{"pdf_hash": "5f4ced687f151dd727283c0e99fd3841c1c80028", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. A 56-year-old patient with no clinical symptoms and ECOG 0. CT, baseline (A) and after (B) response evaluation demonstrated response to therapy as the liver metastases disappeared, and the peritoneal metastases shrunk (red arrows). Due to alterations in the total tumor burden, the patient was classified as stable disease according to irRECIST. 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{"pdf_hash": "f03fe46d4d21556c225e1bd27ae2283f9cff161e", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig 1. Follow-up of a patient affected by diabetic macular edema undergoing Ozurdex implant. Optical coherence tomography scans and MP1 microperimetry outputs, from a 62-year-old patient affected by diabetic macular edema in his right eye, acquired at baseline visit, 1 month, 2 months, 3 months, 4 months and 5 months after the first Ozurdex injection. The patient underwent a second Ozurdex implant at 5 th month because of edema reappearance.", "width": 1498, "height": 434, "subcaptions": {"a": [45, 46], "b": [64, 65, 66, 48, 49, 62, 63], "c": [64, 65, 66, 51, 52, 62, 63], "d": [64, 65, 66, 54, 55, 62, 63], "e": [64, 65, 66, 57, 58, 62, 63], "f": [60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83]}, "subfigures": [{"id": "a520f073-fbd9-4534-97d2-a3dd6a99d76c", "label": "a", "points": [[4.7, 7.1], [4.7, 397.6], [248.5, 397.6], [248.5, 7.1]], "color": "yellow"}, {"id": "ccf95840-96cc-4e94-ae33-327d29075063", "label": "b", "points": [[255.6, 397.6], [255.6, 2.4], [489.9, 2.4], [489.9, 397.6]], "color": "cyan"}, {"id": "5eeee502-bfc3-451b-a3a5-7ae419a11361", "label": "c", "points": [[494.6, 2.4], [494.6, 404.7], [738.4, 404.7], [738.4, 2.4]], "color": "magenta"}, {"id": "de101775-c127-4879-9a14-e7b8f76f2658", "label": "d", "points": [[745.5, 402.3], [745.5, 7.1], [989.2, 7.1], [989.2, 402.3]], 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{"pdf_hash": "57457e1a9d0dd6e229d1333f1f4a8d38bc472013", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Vascular findings of color Doppler ultrasonography, power Doppler ultrasonography, and superb microvascular imaging (SMI) of a 65-year-old woman with invasive ductal carcinoma. A. Gray-scale ultrasonography shows an irregular indistinct or microlobulated hypoechoic mass in the left breast, assessed as, Breast Imaging Reporting and Data System category 4C. B. SMI shows multiple branching and penetrating vessels within the mass. C, D. 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{"pdf_hash": "77f5b2af6b61d89bef42cad463236de428b96b0c", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig. 1 Me-4FDG, MRI, and 2-FDG PET scans on 26-year-old control subject. The Me-4FDG S/N (SUVR/BG) scale 0\u201310 is shown for the NIH color scale, and the 2-FDG SUVR scale is 0.1\u20132.5 for the Hot-Iron color scale", "width": 1182, "height": 590, "subcaptions": {"a": [3], "b": [5], "c": [8, 9]}, "subfigures": [{"id": "2adebcef-1cb4-4d0e-bb51-80510b330825", "label": "a", "points": [[27.6, 18.4], [27.6, 580.4], [427.2, 580.4], [427.2, 18.4]], "color": "yellow"}, {"id": "735ac217-8ba2-43b2-96f5-8c6723a4eb3a", "label": "b", "points": [[434.7, 12.8], [434.7, 580.4], [817.4, 580.4], [817.4, 12.8]], "color": "cyan"}, {"id": "f03e9ae9-a98f-4ce3-8b25-47418357ad7e", "label": "c", "points": [[824.9, 7.2], [824.9, 584.1], [1177.8, 584.1], [1177.8, 7.2]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Me-4FDG", "start": 7, "end": 14, "id": 3}, {"text": ",", "start": 14, "end": 15, "id": 4}, {"text": "MRI", "start": 16, "end": 19, "id": 5}, {"text": ",", "start": 19, "end": 20, "id": 6}, {"text": "and", "start": 21, "end": 24, "id": 7}, {"text": "2-FDG", "start": 25, "end": 30, "id": 8}, {"text": "PET", "start": 31, "end": 34, "id": 9}, {"text": "scans", "start": 35, "end": 40, "id": 10}, {"text": "on", "start": 41, "end": 43, "id": 11}, {"text": "26-year", "start": 44, "end": 51, "id": 12}, {"text": "-", "start": 51, "end": 52, "id": 13}, {"text": "old", "start": 52, "end": 55, "id": 14}, {"text": "control", "start": 56, "end": 63, "id": 15}, {"text": "subject", "start": 64, "end": 71, "id": 16}, {"text": ".", "start": 71, "end": 72, "id": 17}, {"text": "The", "start": 73, "end": 76, "id": 18}, {"text": "Me-4FDG", "start": 77, "end": 84, "id": 19}, {"text": "S", "start": 85, "end": 86, "id": 20}, {"text": "/", "start": 86, "end": 87, "id": 21}, {"text": "N", "start": 87, "end": 88, "id": 22}, {"text": "(", "start": 89, "end": 90, "id": 23}, {"text": "SUVR", "start": 90, "end": 94, "id": 24}, {"text": "/", "start": 94, "end": 95, "id": 25}, {"text": "BG", "start": 95, "end": 97, "id": 26}, {"text": ")", "start": 97, "end": 98, "id": 27}, {"text": "scale", "start": 99, "end": 104, "id": 28}, {"text": "0\u201310", "start": 105, "end": 109, "id": 29}, {"text": "is", "start": 110, "end": 112, "id": 30}, {"text": "shown", "start": 113, "end": 118, "id": 31}, {"text": "for", "start": 119, "end": 122, "id": 32}, {"text": "the", "start": 123, "end": 126, "id": 33}, {"text": "NIH", "start": 127, "end": 130, "id": 34}, {"text": "color", "start": 131, "end": 136, "id": 35}, {"text": "scale", "start": 137, "end": 142, "id": 36}, {"text": ",", "start": 142, "end": 143, "id": 37}, {"text": "and", "start": 144, "end": 147, "id": 38}, {"text": "the", "start": 148, "end": 151, "id": 39}, {"text": "2-FDG", "start": 152, "end": 157, "id": 40}, {"text": "SUVR", "start": 158, "end": 162, "id": 41}, {"text": "scale", "start": 163, "end": 168, "id": 42}, {"text": "is", "start": 169, "end": 171, "id": 43}, {"text": "0.1\u20132.5", "start": 172, "end": 179, "id": 44}, {"text": "for", "start": 180, "end": 183, "id": 45}, {"text": "the", "start": 184, "end": 187, "id": 46}, {"text": "Hot", "start": 188, "end": 191, "id": 47}, {"text": "-", "start": 191, "end": 192, "id": 48}, {"text": "Iron", "start": 192, "end": 196, "id": 49}, {"text": "color", "start": 197, "end": 202, "id": 50}, {"text": "scale", "start": 203, "end": 208, "id": 51}]}
{"pdf_hash": "5c1c06b077d44bd8f3ccde881a3299d95d49e2ba", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Fig. 6 Micro-SORS on a painted sculpture of Christ\u2019s disciple from Varese Sacred Mount in Northern Italy: (a) fragment image (the white square indicates the area analysed with micro-spatially offset Raman spectroscopy); (b) optical image and scheme of the stratigraphy; and (c) the defocused spectra are shown for different distances from the imaged plane indicated next to each spectrum (0 = \u2018imaged\u2019 position). The spectra are offset for clarity. Note that the line markers are for guidance to emphasise the changing relative intensity of the red lead, cinnabar and lead white with defocusing. The reference spectra are acquired on the sample cross section using conventional Raman spectroscopy.3", "width": 1218, "height": 972, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "c": [128, 129, 130, 131, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "17f3be3d-97bb-4609-9ef2-8d0718adc9d5", "label": "a", "points": [[37.1, 6.5], [37.1, 422.1], [587.4, 422.1], [587.4, 6.5]], "color": "yellow"}, {"id": "b5d6f944-73e8-4d01-9140-a27bf71fe917", "label": "b", "points": [[631.7, 10.3], [631.7, 422.1], [1182, 422.1], [1182, 10.3]], "color": "cyan"}, {"id": "49554bb8-5ef2-467e-9bd8-f97284bdbb1f", 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{"pdf_hash": "682d9159261d6fffe64ab10cb63fe938bc41a5be", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Msi-1 expression correlates spatiotemporally with adult progenitor cells during intestinal remodeling. Cross-sections were immunostained with Msi-1 (A,C,F,H), PCNA (E,I) and IFABP (J) antibodies and stained with methyl green-pyronin Y (B,D,G). (A) Stage 57. The larval epithelium (LE) is negative for Msi-1. (B,C) Stage 60. Progenitor cells of the adult epithelium between the larval epithelium and the connective tissue (CT) are weakly positive for Msi-1 (arrowheads). (D-F) Stage 61. The adult epithelium (AE), where PCNA-positive cells are localized, is positive for Msi-1. The degenerating larval epithelium remains negative. (G-J) Stage 63. The adult epithelium completely replaces the larval one. Msi-1-immunoreactivity is weakly detectable only in the trough of newly formed folds (Fo), where PCNA-positive cells are localized (I; arrows). IFABP immunoreactivity increases in intensity from the crest to the trough of the folds. 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{"pdf_hash": "48522f90a6782040a8c9d48b24e2c01c792315d1", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Chest and abdominal computed tomography scans obtained at 17 months after radiofrequency ablation. (A and B) The biloma ruptured into the pleural and abdominal cavity via the injured diaphragm (black arrows), with (C) pneumonia and atelectasis observed in the right lower lung lobe (white arrow) and (D) biliary sludge and small biliary calculi detected in the dilated bile duct (white arrowhead).", "width": 1104, "height": 1046, "subcaptions": {"a": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "c": [59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78]}, "subfigures": [{"id": "c341743a-d47c-4925-8fb4-74a88885f80e", "label": "a", "points": [[51.1, 8.5], [51.1, 500.3], [546.4, 500.3], [546.4, 8.5]], "color": "yellow"}, {"id": "9b47e15e-b552-49f1-a3b0-f7a50a37768e", "label": "c", "points": [[38.9, 510.8], [38.9, 1011.3], [553.4, 1011.3], [553.4, 510.8]], "color": "magenta"}, {"id": "ae625eb6-0f97-4f63-a5be-8490cb51e346", "label": "d", "points": [[605.7, 510.8], [605.7, 1006.1], [1101, 1006.1], [1101, 510.8]], "color": "springgreen"}, 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{"pdf_hash": "d31cdfba31e801d70d4a3d47d0b2668535a81a52", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Morphology of wild-type and 413.d homozygous mutant embryos at the early primitive streak stage. (A) and (B) both show the morphological appearance of a 413.d mutant embryo (d/d) compared with that of a wild-type (wt) littermate. The parietal endoderm has been reflected to reveal the extra-embryonic and embryonic regions of the embryos. Both of the normal embryos were at the mid-streak stage based on the visible extent of the primitive streak and T antibody staining. Neither of the 413.d mutant embryos had recognizable primitive streak structures, or stained positively for expression of T protein. Note the presence of the primitive streak (ps) in the normal embryo in B (indicated by vertical arrows), and the absence of a morphological streak in 413.d mutant embryos. In mutant embryos, a clear demarcation between the embryonic and extra-embryonic regions is not readily evident. (C) Representative sagittal section through a presumed 413.d mutant embryo at 6.5 days p.c. Analysis of complete serial sections failed to show any evidence of localized thickening of the embryonic ectoderm indicative of the primitive streak, or of the formation of a mesodermal layer. Note the striking disturbance of the extra-embryonic ectoderm. 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{"pdf_hash": "135037b072baa2e1d5f65bf9163b9e3381354925", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. A 28-year-old male with a high-grade glioma (WHO grade III) in the left temporal lobe. Axial post-gadolinium T1-weighted image with tumor VOI (a), diffusion-weighted images at b-values of 0 s/mm2 (b), 1000 s/mm2 (c), 2000 s/mm2 (d), and 4000 s/mm2 (e), and isotropic ADC (f ), DDC (g), and a (h) maps show the tumor (arrow). This tumor had a mean DDC of 1.01 10 3mm2/s and a mean a value of 0.55. 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{"pdf_hash": "97ed62e68e852613024ab2fc80b0381598c81f28", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "FIGURE 1 | We performed a clinical practice study investigating the cortical modulation of pupillary function following strategic cerebral strokes. This figure depicts CT of the brain from 2 exemplary stroke patients 24 h following endovascular therapy for large vessel occlusive stroke. Strategic ischemic infarctions are seen in the left prefrontal eye field (Left) and right insular cortex (Central). Using automated pupillometry [(Right); courtesy of https://commons.wikimedia.org/wiki/Main_Page], we collected pupillometry data of patients with strategic infarcts in the prefrontal eye field and/or insular cortex (group 1) and compared them to data from stroke patients without infarcts in these areas (group 2) and to data from patients with myocardial infarcts but without clinical evidence of brain injury (control group).", "width": 1226, "height": 630, "subcaptions": {"a": [65, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "b": [64, 65, 44, 45, 46, 47, 48, 49, 50, 59, 60, 61, 62, 63], "c": [128, 129, 130, 131, 132, 133, 134, 135, 136, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "867a5408-bec5-456d-b785-58cdb6df3030", 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{"pdf_hash": "789984040155a5382eef0a5b5023a12c1e2e3680", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Necrosis in rhino-orbito-cerebral mycormycosis. (A): ROC Mucormycosis with palatal involvement and necrosis. (B): Endoscopic examination shows necrosis of the middle right meatus. Used with kind permission from B. Verillaud, personal data.", "width": 1104, "height": 464, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "d14e7786-543e-4d2d-977f-471ff07ded41", "label": "a", "points": [[4.4, 5.2], [4.4, 458.7], [553.8, 458.7], [553.8, 5.2]], "color": "yellow"}, {"id": "46dc319c-a277-4360-913a-efd853f104ed", "label": "b", "points": [[571.3, 5.2], [571.3, 456.7], [1097.9, 456.7], [1097.9, 5.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Necrosis", "start": 10, "end": 18, "id": 3}, {"text": "in", "start": 19, "end": 21, "id": 4}, {"text": "rhino", "start": 22, "end": 27, "id": 5}, {"text": "-", "start": 27, "end": 28, "id": 6}, {"text": "orbito", "start": 28, "end": 34, "id": 7}, {"text": "-", "start": 34, "end": 35, "id": 8}, {"text": "cerebral", "start": 35, "end": 43, "id": 9}, {"text": "mycormycosis", "start": 44, "end": 56, "id": 10}, {"text": ".", "start": 56, "end": 57, "id": 11}, {"text": "(", "start": 58, "end": 59, "id": 12}, {"text": "A", "start": 59, "end": 60, "id": 13}, {"text": ")", "start": 60, "end": 61, "id": 14}, {"text": ":", "start": 61, "end": 62, "id": 15}, {"text": "ROC", "start": 63, "end": 66, "id": 16}, {"text": "Mucormycosis", "start": 67, "end": 79, "id": 17}, {"text": "with", "start": 80, "end": 84, "id": 18}, {"text": "palatal", "start": 85, "end": 92, "id": 19}, {"text": "involvement", "start": 93, "end": 104, "id": 20}, {"text": "and", "start": 105, "end": 108, "id": 21}, {"text": "necrosis", "start": 109, "end": 117, "id": 22}, {"text": ".", "start": 117, "end": 118, "id": 23}, {"text": "(", "start": 119, "end": 120, "id": 24}, {"text": "B", "start": 120, "end": 121, "id": 25}, {"text": ")", "start": 121, "end": 122, "id": 26}, {"text": ":", "start": 122, "end": 123, "id": 27}, {"text": "Endoscopic", "start": 124, "end": 134, "id": 28}, {"text": "examination", "start": 135, "end": 146, "id": 29}, {"text": "shows", "start": 147, "end": 152, "id": 30}, {"text": "necrosis", "start": 153, "end": 161, "id": 31}, {"text": "of", "start": 162, "end": 164, "id": 32}, {"text": "the", "start": 165, "end": 168, "id": 33}, {"text": "middle", "start": 169, "end": 175, "id": 34}, {"text": "right", "start": 176, "end": 181, "id": 35}, {"text": "meatus", "start": 182, "end": 188, "id": 36}, {"text": ".", "start": 188, "end": 189, "id": 37}, {"text": "Used", "start": 190, "end": 194, "id": 38}, {"text": "with", "start": 195, "end": 199, "id": 39}, {"text": "kind", "start": 200, "end": 204, "id": 40}, {"text": "permission", "start": 205, "end": 215, "id": 41}, {"text": "from", "start": 216, "end": 220, "id": 42}, {"text": "B.", "start": 221, "end": 223, "id": 43}, {"text": "Verillaud", "start": 224, "end": 233, "id": 44}, {"text": ",", "start": 233, "end": 234, "id": 45}, {"text": "personal", "start": 235, "end": 243, "id": 46}, {"text": "data", "start": 244, "end": 248, "id": 47}, {"text": ".", "start": 248, "end": 249, "id": 48}]}
{"pdf_hash": "8eb56aec4b98a54afafec2fc58aa2c27a4dac619", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Representative MR Images of acute soft-tissue infection. A, B) Mouse received PFC at day 2 post infection. Images were recorded 24 h after administration. C, D) Mouse received CLIO at day 2 post infection and was imaged 24 h after administration. A) Transverse T 2 map of PFC group mouse shows hyperintensity within infected muscle (arrow). B) 19 F-SSFP CSI overlay on 1 H-TSE image of PFC treated mouse shows strong accumulation of PFC at the rim of abscess area. C) Transverse T 2 map of CLIO group mouse shows hyper-intense area diffusely circumscribed by dark spots (arrow). D) T 2 * weighted image shows diffusely distributed susceptibility effects in the infected muscle (arrow). 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{"pdf_hash": "75789e23754d439780308d4e61a5f4167ad41ce3", "fig_key": "Figure17", "fig_uri": "16-Figure17-1.png", "text": "FIGURE 17 Increase in osmium-fixed radioactivity in the photoreceptors with time of incubation . (A) Retina fixed immediately after labeling. (B) Retina labeled in the same way and subsequently incubated for I h in the presence of 1 mM unlabeled choline . At the end of the chase (B) a significant number of grains is seen over the photoreceptor outer segments . Even then, the majority of grains are over the outer nuclear layer or inner segments . Cones (arrows) were more heavily labeled than rods . Note (B) that much more osmium-fixed radioactivity is contained in the photoreceptors than in the outer plexiform or outer nuclear layers. Exposure, 4 wk . 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{"pdf_hash": "cb30c36c713cff28091180ff4e6b7b59a3f0b46e", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Magnetic Resonance Imaging (MRI) of the brain performed after SE recovery. In (A) Axial Fluid Attenuated Inversion Recovery (FLAIR) sequence and in (B) T2-weightened sequences showing a large neoplastic lesion involving the left temporoinsular area.", "width": 670, "height": 408, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "e6ff40fa-05a1-4e18-8736-c36f2fb5302b", "label": "a", "points": [[3.7, 25.4], [3.7, 401.2], [328.7, 401.2], [328.7, 25.4]], "color": "yellow"}, {"id": "012feffe-a638-4691-835b-2314aad355cd", "label": "b", "points": [[336.1, 26.5], [336.1, 404.4], [665.3, 404.4], [665.3, 26.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Magnetic", "start": 8, "end": 16, "id": 4}, {"text": "Resonance", "start": 17, "end": 26, "id": 5}, {"text": "Imaging", "start": 27, "end": 34, "id": 6}, {"text": "(", "start": 35, "end": 36, "id": 7}, {"text": "MRI", "start": 36, "end": 39, "id": 8}, {"text": ")", "start": 39, "end": 40, "id": 9}, {"text": "of", "start": 41, "end": 43, "id": 10}, {"text": "the", "start": 44, "end": 47, "id": 11}, {"text": "brain", "start": 48, "end": 53, "id": 12}, {"text": "performed", "start": 54, "end": 63, "id": 13}, {"text": "after", "start": 64, "end": 69, "id": 14}, {"text": "SE", "start": 70, "end": 72, "id": 15}, {"text": "recovery", "start": 73, "end": 81, "id": 16}, {"text": ".", "start": 81, "end": 82, "id": 17}, {"text": "In", "start": 83, "end": 85, "id": 18}, {"text": "(", "start": 86, "end": 87, "id": 19}, {"text": "A", "start": 87, "end": 88, "id": 20}, {"text": ")", "start": 88, "end": 89, "id": 21}, {"text": "Axial", "start": 90, "end": 95, "id": 22}, {"text": "Fluid", "start": 96, "end": 101, "id": 23}, {"text": "Attenuated", "start": 102, "end": 112, "id": 24}, {"text": "Inversion", "start": 113, "end": 122, "id": 25}, {"text": "Recovery", "start": 123, "end": 131, "id": 26}, {"text": "(", "start": 132, "end": 133, "id": 27}, {"text": "FLAIR", "start": 133, "end": 138, "id": 28}, {"text": ")", "start": 138, "end": 139, "id": 29}, {"text": "sequence", "start": 140, "end": 148, "id": 30}, {"text": "and", "start": 149, "end": 152, "id": 31}, {"text": "in", "start": 153, "end": 155, "id": 32}, {"text": "(", "start": 156, "end": 157, "id": 33}, {"text": "B", "start": 157, "end": 158, "id": 34}, {"text": ")", "start": 158, "end": 159, "id": 35}, {"text": "T2-weightened", "start": 160, "end": 173, "id": 36}, {"text": "sequences", "start": 174, "end": 183, "id": 37}, {"text": "showing", "start": 184, "end": 191, "id": 38}, {"text": "a", "start": 192, "end": 193, "id": 39}, {"text": "large", "start": 194, "end": 199, "id": 40}, {"text": "neoplastic", "start": 200, "end": 210, "id": 41}, {"text": "lesion", "start": 211, "end": 217, "id": 42}, {"text": "involving", "start": 218, "end": 227, "id": 43}, {"text": "the", "start": 228, "end": 231, "id": 44}, {"text": "left", "start": 232, "end": 236, "id": 45}, {"text": "temporoinsular", "start": 237, "end": 251, "id": 46}, {"text": "area", "start": 252, "end": 256, "id": 47}, {"text": ".", "start": 256, "end": 257, "id": 48}]}
{"pdf_hash": "bebff4703bd58d350869ccaa293f6d8b4514bea6", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 The post-surgical examination: (a) Transverse, (b) sagittal and (c) three-dimensional volume-rendered computed tomography angiography of pre-discharge showed complete sealing of the primary entry tear with the occlude. No endoleak could be found. d Gastroscopic examination revealed the complete healing of original fistulas. *, original esophageal mural ulcers; LCCA, left common carotid artery; LSA, left subclavian artery; INA, innominate artery", "width": 852, "height": 754, "subcaptions": {"a": [9, 10, 11, 12, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [14, 15, 16, 17, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "d": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "0106c924-bd83-4237-99c8-0c3b032e1de9", "label": "a", "points": [[26, 21.4], [26, 337.6], [405.5, 337.6], [405.5, 21.4]], "color": "yellow"}, {"id": "bed89d4b-8d39-4e1c-acdb-fe7ef72b072f", "label": "b", "points": [[410.9, 17.3], [410.9, 360.5], [821.4, 360.5], [821.4, 17.3]], "color": 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{"pdf_hash": "9c3e1a2271343d208bba1a2b0e98eb3aa548ce81", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Atomic resolution images of Co25Fe75 films. Scanning transmission electron microscopy images of a Cr(2.8 nm)/Co25Fe75(6.8 nm)/MgO and b Cr(2.8 nm)/Co25Fe75(6.8 nm)/MAO films viewed along the Co25Fe75 [010] axis, where the boundary between Cr and Co25Fe75 as confirmed by electron energy loss spectroscopy scans is indicated by the dashed line.", "width": 674, "height": 388, "subcaptions": {"a": [16, 17, 18, 19], "b": [21, 22, 23, 24]}, "subfigures": [{"id": "402b1e39-5fc3-4faf-83f3-8a70100ccdee", "label": "a", "points": [[14.4, 3], [14.4, 352.3], [332.8, 352.3], [332.8, 3]], "color": "yellow"}, {"id": "d86f63ed-f70e-4b34-b4d2-d7684dd87eee", "label": "b", "points": [[351.9, 2], [351.9, 354.4], [671.4, 354.4], [671.4, 2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Atomic", "start": 7, "end": 13, "id": 3}, {"text": "resolution", "start": 14, "end": 24, "id": 4}, {"text": "images", "start": 25, "end": 31, "id": 5}, {"text": "of", "start": 32, "end": 34, "id": 6}, {"text": "Co25Fe75", "start": 35, "end": 43, "id": 7}, {"text": "films", "start": 44, "end": 49, "id": 8}, {"text": ".", "start": 49, "end": 50, "id": 9}, {"text": "Scanning", "start": 51, "end": 59, "id": 10}, {"text": "transmission", "start": 60, "end": 72, "id": 11}, {"text": "electron", "start": 73, "end": 81, "id": 12}, {"text": "microscopy", "start": 82, "end": 92, "id": 13}, {"text": "images", "start": 93, "end": 99, "id": 14}, {"text": "of", "start": 100, "end": 102, "id": 15}, {"text": "a", "start": 103, "end": 104, "id": 16}, {"text": "Cr(2.8", "start": 105, "end": 111, "id": 17}, {"text": "nm)/Co25Fe75(6.8", "start": 112, "end": 128, "id": 18}, {"text": "nm)/MgO", "start": 129, "end": 136, "id": 19}, {"text": "and", "start": 137, "end": 140, "id": 20}, {"text": "b", "start": 141, "end": 142, "id": 21}, {"text": "Cr(2.8", "start": 143, "end": 149, "id": 22}, {"text": "nm)/Co25Fe75(6.8", "start": 150, "end": 166, "id": 23}, {"text": "nm)/MAO", "start": 167, "end": 174, "id": 24}, {"text": "films", "start": 175, "end": 180, "id": 25}, {"text": "viewed", "start": 181, "end": 187, "id": 26}, {"text": "along", "start": 188, "end": 193, "id": 27}, {"text": "the", "start": 194, "end": 197, "id": 28}, {"text": "Co25Fe75", "start": 198, "end": 206, "id": 29}, {"text": "[", "start": 207, "end": 208, "id": 30}, {"text": "010", "start": 208, "end": 211, "id": 31}, {"text": "]", "start": 211, "end": 212, "id": 32}, {"text": "axis", "start": 213, "end": 217, "id": 33}, {"text": ",", "start": 217, "end": 218, "id": 34}, {"text": "where", "start": 219, "end": 224, "id": 35}, {"text": "the", "start": 225, "end": 228, "id": 36}, {"text": "boundary", "start": 229, "end": 237, "id": 37}, {"text": "between", "start": 238, "end": 245, "id": 38}, {"text": "Cr", "start": 246, "end": 248, "id": 39}, {"text": "and", "start": 249, "end": 252, "id": 40}, {"text": "Co25Fe75", "start": 253, "end": 261, "id": 41}, {"text": "as", "start": 262, "end": 264, "id": 42}, {"text": "confirmed", "start": 265, "end": 274, "id": 43}, {"text": "by", "start": 275, "end": 277, "id": 44}, {"text": "electron", "start": 278, "end": 286, "id": 45}, {"text": "energy", "start": 287, "end": 293, "id": 46}, {"text": "loss", "start": 294, "end": 298, "id": 47}, {"text": "spectroscopy", "start": 299, "end": 311, "id": 48}, {"text": "scans", "start": 312, "end": 317, "id": 49}, {"text": "is", "start": 318, "end": 320, "id": 50}, {"text": "indicated", "start": 321, "end": 330, "id": 51}, {"text": "by", "start": 331, "end": 333, "id": 52}, {"text": "the", "start": 334, "end": 337, "id": 53}, {"text": "dashed", "start": 338, "end": 344, "id": 54}, {"text": "line", "start": 345, "end": 349, "id": 55}, {"text": ".", "start": 349, "end": 350, "id": 56}]}
{"pdf_hash": "eec0002dc1d2e2d0c2e159fdb9b50b6208b01e9b", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. A. Endoscopic retroflex view showing a 10-mm opening flap created after marking the normal antral mucosa around the lesion with 10-mm margins. B. Endoscopic findings showing a whitish mass (yellow surrounded) through the dissected submucosal tunnel. Tissue samples using biopsy forceps confirmed a poorly differentiated adenocarcinoma.", "width": 946, "height": 502, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43]}, "subfigures": [{"id": "144d7cdc-6967-4377-8785-92951479f270", "label": "a", "points": [[5.3, 40.1], [5.3, 470.5], [467, 470.5], [467, 40.1]], "color": "yellow"}, {"id": "c622aa74-dc8d-4dfc-9ab8-cadb39088406", "label": "b", "points": [[471.5, 37.1], [471.5, 473.5], [939.3, 473.5], [939.3, 37.1]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A.", "start": 8, "end": 10, "id": 4}, {"text": "Endoscopic", "start": 11, "end": 21, "id": 5}, {"text": "retroflex", "start": 22, "end": 31, "id": 6}, {"text": "view", "start": 32, "end": 36, "id": 7}, {"text": "showing", "start": 37, "end": 44, "id": 8}, {"text": "a", "start": 45, "end": 46, "id": 9}, {"text": "10-mm", "start": 47, "end": 52, "id": 10}, {"text": "opening", "start": 53, "end": 60, "id": 11}, {"text": "flap", "start": 61, "end": 65, "id": 12}, {"text": "created", "start": 66, "end": 73, "id": 13}, {"text": "after", "start": 74, "end": 79, "id": 14}, {"text": "marking", "start": 80, "end": 87, "id": 15}, {"text": "the", "start": 88, "end": 91, "id": 16}, {"text": "normal", "start": 92, "end": 98, "id": 17}, {"text": "antral", "start": 99, "end": 105, "id": 18}, {"text": "mucosa", "start": 106, "end": 112, "id": 19}, {"text": "around", "start": 113, "end": 119, "id": 20}, {"text": "the", "start": 120, "end": 123, "id": 21}, {"text": "lesion", "start": 124, "end": 130, "id": 22}, {"text": "with", "start": 131, "end": 135, "id": 23}, {"text": "10-mm", "start": 136, "end": 141, "id": 24}, {"text": "margins", "start": 142, "end": 149, "id": 25}, {"text": ".", "start": 149, "end": 150, "id": 26}, {"text": "B.", "start": 151, "end": 153, "id": 27}, {"text": "Endoscopic", "start": 154, "end": 164, "id": 28}, {"text": "findings", "start": 165, "end": 173, "id": 29}, {"text": "showing", "start": 174, "end": 181, "id": 30}, {"text": "a", "start": 182, "end": 183, "id": 31}, {"text": "whitish", "start": 184, "end": 191, "id": 32}, {"text": "mass", "start": 192, "end": 196, "id": 33}, {"text": "(", "start": 197, "end": 198, "id": 34}, {"text": "yellow", "start": 198, "end": 204, "id": 35}, {"text": "surrounded", "start": 205, "end": 215, "id": 36}, {"text": ")", "start": 215, "end": 216, "id": 37}, {"text": "through", "start": 217, "end": 224, "id": 38}, {"text": "the", "start": 225, "end": 228, "id": 39}, {"text": "dissected", "start": 229, "end": 238, "id": 40}, {"text": "submucosal", "start": 239, "end": 249, "id": 41}, {"text": "tunnel", "start": 250, "end": 256, "id": 42}, {"text": ".", "start": 256, "end": 257, "id": 43}, {"text": "Tissue", "start": 258, "end": 264, "id": 44}, {"text": "samples", "start": 265, "end": 272, "id": 45}, {"text": "using", "start": 273, "end": 278, "id": 46}, {"text": "biopsy", "start": 279, "end": 285, "id": 47}, {"text": "forceps", "start": 286, "end": 293, "id": 48}, {"text": "confirmed", "start": 294, "end": 303, "id": 49}, {"text": "a", "start": 304, "end": 305, "id": 50}, {"text": "poorly", "start": 306, "end": 312, "id": 51}, {"text": "differentiated", "start": 313, "end": 327, "id": 52}, {"text": "adenocarcinoma", "start": 328, "end": 342, "id": 53}, {"text": ".", "start": 342, "end": 343, "id": 54}]}
{"pdf_hash": "4f46047924e9ac6a13deab7f860fc85489cac6d8", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3 Coronal brain sections in rat models of hypoxic-ischemic encephalopathy (TTC staining). (A) Control group; (B) model group. Red: Normal tissue; white: ischemic tissue.", "width": 670, "height": 396, "subcaptions": {"a": [18, 19, 20, 21, 22], "b": [24, 25, 26, 27, 28]}, "subfigures": [{"id": "ee46d3d6-6dcb-4aa0-877f-91b8026420cc", "label": "a", "points": [[0.6, 1.9], [0.6, 177.6], [668.4, 177.6], [668.4, 1.9]], "color": "yellow"}, {"id": "5a810c36-0d98-4113-91ca-4a6c85ef97db", "label": "b", "points": [[2.7, 186.1], [2.7, 360.7], [666.3, 360.7], [666.3, 186.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "Coronal", "start": 9, "end": 16, "id": 2}, {"text": "brain", "start": 17, "end": 22, "id": 3}, {"text": "sections", "start": 23, "end": 31, "id": 4}, {"text": "in", "start": 32, "end": 34, "id": 5}, {"text": "rat", "start": 35, "end": 38, "id": 6}, {"text": "models", "start": 39, "end": 45, "id": 7}, {"text": "of", "start": 46, "end": 48, "id": 8}, {"text": "hypoxic", "start": 49, "end": 56, "id": 9}, {"text": "-", "start": 56, "end": 57, "id": 10}, {"text": "ischemic", "start": 57, "end": 65, "id": 11}, {"text": "encephalopathy", "start": 66, "end": 80, "id": 12}, {"text": "(", "start": 81, "end": 82, "id": 13}, {"text": "TTC", "start": 82, "end": 85, "id": 14}, {"text": "staining", "start": 86, "end": 94, "id": 15}, {"text": ")", "start": 94, "end": 95, "id": 16}, {"text": ".", "start": 95, "end": 96, "id": 17}, {"text": "(", "start": 97, "end": 98, "id": 18}, {"text": "A", "start": 98, "end": 99, "id": 19}, {"text": ")", "start": 99, "end": 100, "id": 20}, {"text": "Control", "start": 101, "end": 108, "id": 21}, {"text": "group", "start": 109, "end": 114, "id": 22}, {"text": ";", "start": 114, "end": 115, "id": 23}, {"text": "(", "start": 116, "end": 117, "id": 24}, {"text": "B", "start": 117, "end": 118, "id": 25}, {"text": ")", "start": 118, "end": 119, "id": 26}, {"text": "model", "start": 120, "end": 125, "id": 27}, {"text": "group", "start": 126, "end": 131, "id": 28}, {"text": ".", "start": 131, "end": 132, "id": 29}, {"text": "Red", "start": 133, "end": 136, "id": 30}, {"text": ":", "start": 136, "end": 137, "id": 31}, {"text": "Normal", "start": 138, "end": 144, "id": 32}, {"text": "tissue", "start": 145, "end": 151, "id": 33}, {"text": ";", "start": 151, "end": 152, "id": 34}, {"text": "white", "start": 153, "end": 158, "id": 35}, {"text": ":", "start": 158, "end": 159, "id": 36}, {"text": "ischemic", "start": 160, "end": 168, "id": 37}, {"text": "tissue", "start": 169, "end": 175, "id": 38}, {"text": ".", "start": 175, "end": 176, "id": 39}]}
{"pdf_hash": "e512277fbb2ef655f4477d15b357ae097982964c", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. A Early gastric cancer (0-IIa + IIc type; 15 mm), of the fundus, along the lesser curvature just below the cardia, after staining with indigo-carmine. B Residual ulcer after endoscopic submucosal dissection. C En-bloc excised lesion fi xed and orientated on a board for histopathological assessment. D Well-differentiated (G1) intramucosal adenocarcinoma of intestinal type, vertical margins free of tumor. 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{"pdf_hash": "8dadae5aa2c8f083fc8fc128a42184fdb7341ec2", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "FIG. 2. Histology of the thyroid gland in RET-MEN2A transgenic mice. (A) Histologic appearance of a thyroid gland from a nontransgenic mouse. F, follicles; P, parathyroid gland; T, trachea. (Bar5 50mm.) (B) Distribution of thyroid C cells in a nontransgenic mouse demonstrated by CT immunostaining. Arrows, CT-positive C cells. (Bar 5 10 mm.) (C) Diffuse CCH in a transgenic mouse of 4 weeks of age. Note the increased number of C cells throughout the lobe detected by CT immunohistochemistry. (Bar5 50 mm.) (D) Small primary focus of MTC. Malignant cells have infiltrated and obliterated thyroid follicles. (E) MTC with massive invasion of one lobe. Arrows, remnants of thyroid follicles at the peripehry of the tumor mass. (Bar 5 50 mm.) (F) Higher magnification of the slide displayed inE showing endocrine lobular and solid pattern characteristic ofMTC. (Bar5 20mm.) (G) Calcitonin immunostaining of MTC cells. Note that a fraction of malignant cells expressed CT, a feature reminiscent of human MTC. (Bar 5 10 mm.) (H) Metastatic MTC nodule in a transgenic mouse liver. Large arrow, metastatic nodule; small arrows, normal liver. 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{"pdf_hash": "2a5141ddefe656cf6dcfd82f61dda1f55c91a844", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. A 52-year-old woman with idiopathic synovial osteochondromatosis of the left hip. A. Anteoposterior radiograph of the left hip depicts juxta-articular calicified and/ or ossified bodies (arrowheads), and an osteophyte (straight arrow). Note that superior to the iliopubic line, a calcified and/ or ossified body (curved arrow) is also present, suggesting intrapelvic extension of the lesion. B. T1-weighted coronal MR image of the same patient shows an intra-articular lesion of low signal intensity (curved arrows), signal intensity which corresponds to an area of fat (straight arrow), and a conglomerated lesion (open arrow). Note that intrapelvic extension of the iliopsoas bursa has occurred (arrowheads). C. T2-weighted image, obtained at the same level as in B, shows intra-articular bodies of focal low signal intensity (curved arrows), and a conglomerated lesion (straight arrow). 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{"pdf_hash": "c9786c0697342854b7998b64fb355b5577efba0c", "fig_key": "Figure2", "fig_uri": "11-Figure2-1.png", "text": "Figure 2. Electron micrographs of the median eminence are shown, with transmission EM (TEM, A-E left) and scanning EM (SEM, F-K right). A) Half of the median eminence is shown in a low magnification TEM section, oriented with a slight angle to show the structures from the ventral 3rd ventricle (3V) to the dorsal portal capillary (Cap). Distinctive cellular structures of the four zones (I, II, III, IV) from the 3rd ventricle to the portal capillary are show in higher magnification in panels B, C, D and E, respectively. The corresponding SEM micrograph (F) shows the median eminence on a 100 \u00b5m coronal section. Tissue is oriented at a slight angle to show the floor of the 3rd ventricle and the cryo-fractured lateral median eminence. 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{"pdf_hash": "ce9fe99e5a844359ff73433b6b16374517169ba8", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4 Lateral cervical spine radiography in neutral (a), flexion (b) and extension (c) demonstrated no instability of the atlantoaxial complex 18 months after the operation", "width": 1016, "height": 468, "subcaptions": {"a": [8, 9, 10, 11], "b": [13, 14, 15, 16], "c": [18, 19, 20, 21]}, "subfigures": [{"id": "3e00dc58-ec91-4f3d-86e6-6d91fc1d6ba6", "label": "a", "points": [[4.1, 1.3], [4.1, 465.2], [331.5, 465.2], [331.5, 1.3]], "color": "yellow"}, {"id": "39bae569-898c-4a17-952f-f1fc6d92ccee", "label": "b", "points": [[344.3, -0.3], [344.3, 465.2], [676.6, 465.2], [676.6, -0.3]], "color": "cyan"}, {"id": "6706fbdf-d50c-48c6-bff8-2d9225e0c01d", "label": "c", "points": [[686.2, 1.3], [686.2, 466.8], [1010.4, 466.8], [1010.4, 1.3]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Lateral", "start": 7, "end": 14, "id": 3}, {"text": "cervical", "start": 15, "end": 23, "id": 4}, {"text": "spine", "start": 24, "end": 29, "id": 5}, {"text": "radiography", "start": 30, "end": 41, "id": 6}, {"text": "in", "start": 42, "end": 44, "id": 7}, {"text": "neutral", "start": 45, "end": 52, "id": 8}, {"text": "(", "start": 53, "end": 54, "id": 9}, {"text": "a", "start": 54, "end": 55, "id": 10}, {"text": ")", "start": 55, "end": 56, "id": 11}, {"text": ",", "start": 56, "end": 57, "id": 12}, {"text": "flexion", "start": 58, "end": 65, "id": 13}, {"text": "(", "start": 66, "end": 67, "id": 14}, {"text": "b", "start": 67, "end": 68, "id": 15}, {"text": ")", "start": 68, "end": 69, "id": 16}, {"text": "and", "start": 70, "end": 73, "id": 17}, {"text": "extension", "start": 74, "end": 83, "id": 18}, {"text": "(", "start": 84, "end": 85, "id": 19}, {"text": "c", "start": 85, "end": 86, "id": 20}, {"text": ")", "start": 86, "end": 87, "id": 21}, {"text": "demonstrated", "start": 88, "end": 100, "id": 22}, {"text": "no", "start": 101, "end": 103, "id": 23}, {"text": "instability", "start": 104, "end": 115, "id": 24}, {"text": "of", "start": 116, "end": 118, "id": 25}, {"text": "the", "start": 119, "end": 122, "id": 26}, {"text": "atlantoaxial", "start": 123, "end": 135, "id": 27}, {"text": "complex", "start": 136, "end": 143, "id": 28}, {"text": "18", "start": 144, "end": 146, "id": 29}, {"text": "months", "start": 147, "end": 153, "id": 30}, {"text": "after", "start": 154, "end": 159, "id": 31}, {"text": "the", "start": 160, "end": 163, "id": 32}, {"text": "operation", "start": 164, "end": 173, "id": 33}]}
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{"pdf_hash": "9b0056b1e6e9062ea158989f7df7088b0f894911", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 A 45-year-old female with diabetes, antiretroviral-treated human immunodeficiency virus (HIV) infection and left partial staghorn nephrolithiasis at previous plain radiograph (A) and MDCT urography (B) presented 9 weeks after percutaneous nephrolithotomy (PCNL) with clinical and contrast-enhanced MDCT (C, D) evidence of nephrocutaneous fistulisation reaching a cutaneous orifice (arrowheads). Associated findings included ipsilateral hydronephrosis with parenchymal thinning, severely thickened hyperenhancing urothelium (thin arrows) in the ureteropelvic junction, proximal and midureter, and multiple residual stone fragments along the lumbar ureter consistent with steinstrasse. Surgical treatment included nephro-ureterectomy with fistula debridement. 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{"pdf_hash": "5476926e3d527fb4877c9a8def0b2a1530d42cf4", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Fig 4. Perimortem fractures LF (in blue) and DF (in red yellow and black) are illustrated in Frontal (A), Occipital (C) Lateral (B,D) views. The right parietal bone of Cioclovina calvaria exhibits a central depressive fracture radiating to the right temporal, occipital and left parietal bones (Fig 2A). The centre of the depression fracture is located on the right parietal bone, approximately 2 cm superiorly to the inferior temporal line. There is an inward displacement of a bowlike bony fragment (r = 35.2 mm). Six linear fractures (R1-R6), radiating from the centre of impact are observed, as well as two main concentric fractures (C1-C2) perpendicular to the radiating fractures (Fig 2B). The first radial fracture (R1) extends superiorly to the centre of impact up to the sagittal suture. There it changes course following the suture towards lambda for about 31 mm. At a distance of approximately 29.5 mm from lambda it turns 90 degrees to the direction of the left parietal bone, crosses the right superior and inferior temporal line and moves slightly posteriorly and downwards to the left parietal squama. It crosses the left squamosal suture in a distance of 40mm from the superior border of the left external acoustic meatus. At that point gives rise to 2 smaller fracture lines (R1a, R1b) which extend to the temporal squama. R1a stops once it meets the temporal suture and R1b reaches the cranial base. R2 starts at the middle of the arc produced by the inward displacement of the central fragment and moves posterior to the right parietal bone stopping at the right lambdoid suture. R3 starts in the middle of the parietal bone, moves to the anterior part of the bone and stops at the edge of a linear fracture (LF). LF starts at the middle left of the inferior nuchal line, moves diagonally accross the tuberculum linearum, crosses the right lamdoid suture, moves slightly inferiorly and anteriorly, crossing the right squamosal suture and the right temporal bone and ends at the inferior part of the right lateral wing of the sphenoid bone (B and C). R4 begins at the impact point slightly posteriorly and then turns inferiorly and parallel to R3, crosses the right inferior temporal line, runs the right parietal bone, and ends at the right squamosal suture about 35.1 mm above the superior border of the right external acoustic meatus. R5 starts from the impact point directly posteriorly to the parietal bone. It turns slightly inferiorly when crossing the inferior temporal line and ends at the right coronal suture. R6 starts at the impact point, moves slightly posteriorly and inferiorly and crosses almost perpendicularly the sagittal suture at a distance of approximately 30.6 mm from bregma. After running approximately 29.5 mm on the posterior part of the left parietal bone, R6 turns 144 degrees anteriorly and inferiorly for approx. 43.9 mm. At the level of the left superior temporal line it turns 131 degrees anteriorly and stops at the R2 fracture line. https://doi.org/10.1371/journal.pone.0216718.g004", "width": 1034, "height": 946, "subcaptions": {"a": [24, 25, 22, 23], "b": [384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 400, 403, 404, 31, 32, 33, 36, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383], "c": [384, 385, 386, 387, 388, 389, 390, 391, 392, 393, 394, 395, 396, 397, 398, 399, 402, 403, 404, 27, 28, 29, 30, 343, 344, 345, 346, 347, 348, 349, 350, 351, 352, 353, 354, 355, 356, 357, 358, 359, 360, 361, 362, 363, 364, 365, 366, 367, 368, 369, 370, 371, 372, 373, 374, 375, 376, 377, 378, 379, 380, 381, 382, 383], "d": [32, 35, 36, 31]}, "subfigures": [{"id": "e48c4160-044f-44bd-9355-50c91d442d8b", "label": "a", "points": [[61.3, 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{"pdf_hash": "4d3e0013b75aa62c6116ff546e9fb5b510d07f22", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 A 43-year-old female with stenosis of the subclavian artery (arrow) and vein (arrowhead) when arms are elevated. Targeted maximum intensity projection of CE-MRA shows strong selective arterial enhancement during first pass of gadofosvesit trisodium (0.03 mmol/kg @ 0.8 ml/s) (a) and prolonged arterial/venous enhancement during steady state (b). Moreover, the long time window of vascular enhancement allows steady-state imaging with arms down (c), showing release of the arterial and venous compression. 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{"pdf_hash": "bd3393fe886b00d5eb79b3959ab106bec427d289", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Axial CT (A), axial (B), and sagittal (C) T2-weighted MR images showing microcephaly and skull collapse. There is moderate ventricular dilatation, enlargement of extra-axial cerebrospinal fluid spaces and thinning of brain parenchyma. The gyral pattern is abnormally smooth for gestational age. Subcortical calcifications are predominantly located in the frontal lobes. 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{"pdf_hash": "bb1e20a7fc8e3752190cb2d63f5ff93cecfe8dcd", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Mycetoma of the foot from Nocardia brasiliensis showing the characteristic triad of tumefaction, fistulae and microcolonies. Central image, an X-ray analysis of the ankle and foot region showing the severe destruction of bones. Right image, a microcolony of N. brasiliensis stained with PAS surrounded by a PMN infiltrate. doi:10.1371/journal.pone.0065425.g001", "width": 1372, "height": 346, "subcaptions": {"a": [0], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "c": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "162e4e41-76f3-401a-94ba-3241fed482c2", "label": "a", "points": [[7.7, 8.3], [7.7, 333.4], [430.3, 333.4], [430.3, 8.3]], "color": "yellow"}, {"id": "7926a9b4-b968-4484-8d37-4f3d8a70e932", "label": "b", "points": [[491, 8.3], [491, 333.4], [885.5, 333.4], [885.5, 8.3]], "color": "cyan"}, {"id": "6355edf4-2a7f-4577-a30c-d300553a5dae", "label": "c", "points": [[920.2, 6.1], [920.2, 337.8], [1355.8, 337.8], [1355.8, 6.1]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Mycetoma", "start": 10, "end": 18, "id": 3}, {"text": "of", "start": 19, "end": 21, "id": 4}, {"text": "the", "start": 22, "end": 25, "id": 5}, {"text": "foot", "start": 26, "end": 30, "id": 6}, {"text": "from", "start": 31, "end": 35, "id": 7}, {"text": "Nocardia", "start": 36, "end": 44, "id": 8}, {"text": "brasiliensis", "start": 45, "end": 57, "id": 9}, {"text": "showing", "start": 58, "end": 65, "id": 10}, {"text": "the", "start": 66, "end": 69, "id": 11}, {"text": "characteristic", "start": 70, "end": 84, "id": 12}, {"text": "triad", "start": 85, "end": 90, "id": 13}, {"text": "of", "start": 91, "end": 93, "id": 14}, {"text": "tumefaction", "start": 94, "end": 105, "id": 15}, {"text": ",", "start": 105, "end": 106, "id": 16}, {"text": "fistulae", "start": 107, "end": 115, "id": 17}, {"text": "and", "start": 116, "end": 119, "id": 18}, {"text": "microcolonies", "start": 120, "end": 133, "id": 19}, {"text": ".", "start": 133, "end": 134, "id": 20}, {"text": "Central", "start": 135, "end": 142, "id": 21}, {"text": "image", "start": 143, "end": 148, "id": 22}, {"text": ",", "start": 148, "end": 149, "id": 23}, {"text": "an", "start": 150, "end": 152, "id": 24}, {"text": "X", "start": 153, "end": 154, "id": 25}, {"text": "-", "start": 154, "end": 155, "id": 26}, {"text": "ray", "start": 155, "end": 158, "id": 27}, {"text": "analysis", "start": 159, "end": 167, "id": 28}, {"text": "of", "start": 168, "end": 170, "id": 29}, {"text": "the", "start": 171, "end": 174, "id": 30}, {"text": "ankle", "start": 175, "end": 180, "id": 31}, {"text": "and", "start": 181, "end": 184, "id": 32}, {"text": "foot", "start": 185, "end": 189, "id": 33}, {"text": "region", "start": 190, "end": 196, "id": 34}, {"text": "showing", "start": 197, "end": 204, "id": 35}, {"text": "the", "start": 205, "end": 208, "id": 36}, {"text": "severe", "start": 209, "end": 215, "id": 37}, {"text": "destruction", "start": 216, "end": 227, "id": 38}, {"text": "of", "start": 228, "end": 230, "id": 39}, {"text": "bones", "start": 231, "end": 236, "id": 40}, {"text": ".", "start": 236, "end": 237, "id": 41}, {"text": "Right", "start": 238, "end": 243, "id": 42}, {"text": "image", "start": 244, "end": 249, "id": 43}, {"text": ",", "start": 249, "end": 250, "id": 44}, {"text": "a", "start": 251, "end": 252, "id": 45}, {"text": "microcolony", "start": 253, "end": 264, "id": 46}, {"text": "of", "start": 265, "end": 267, "id": 47}, {"text": "N.", "start": 268, "end": 270, "id": 48}, {"text": "brasiliensis", "start": 271, "end": 283, "id": 49}, {"text": "stained", "start": 284, "end": 291, "id": 50}, {"text": "with", "start": 292, "end": 296, "id": 51}, {"text": "PAS", "start": 297, "end": 300, "id": 52}, {"text": "surrounded", "start": 301, "end": 311, "id": 53}, {"text": "by", "start": 312, "end": 314, "id": 54}, {"text": "a", "start": 315, "end": 316, "id": 55}, {"text": "PMN", "start": 317, "end": 320, "id": 56}, {"text": "infiltrate", "start": 321, "end": 331, "id": 57}, {"text": ".", "start": 331, "end": 332, "id": 58}, {"text": "doi:10.1371", "start": 333, "end": 344, "id": 59}, {"text": "/", "start": 344, "end": 345, "id": 60}, {"text": "journal.pone.0065425.g001", "start": 345, "end": 370, "id": 61}]}
{"pdf_hash": "30f286c1f6c7311ed91074adf323455803e96603", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1: A representative case of low-grade uterine endometrial stromal sarcoma (L-ESS, 58-y-old patient, FIGO stage I). T2-weighted (A) and contrast-enhanced T1-weighted (B) MR images and 18 F-FDG (C) and 18 F-FES (D) PET images are shown. The 18 F-FDG SUV, 18 F-FES SUV, and 18 F-FDG/ 18 F-FES SUV ratio were 5.4, 12.6, and 0.4, respectively. Immunohistochemistry revealed that ER expression (E) was high and MIB-1 expression (F) was low in this case. 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{"pdf_hash": "27659ca87b7add1dd868c8ff63544eceaa4a7229", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (a) CT of the abdomen coronal and axial views. A complex mass with foci of calcification in gallbladder fossa and 9 cm heterogeneous mass in the right hepatic lobe. 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{"pdf_hash": "9f2936bd6abb5362e59093231b1e36ec67337fe1", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. \u2018\u2018Malignant\u2019\u2019 bone formation within the tumour mass after SaOS-2 transplantation. A, Representative CT image 70 days after intrafemoral transplantation of SaOS-2 cells showing \u2018\u2018malignant\u2019\u2019 bone formation within the extraosseous tumour mass (arrow). B, Representative Maximum Intensity Projection CT image of a mouse bearing a SaOS tumour 70 days after transplantation, showing \u2018\u2018malignant\u2019\u2019 bone formation within the extraosseous tumour mass (arrow). C, \u2018\u2018Malignant\u2019\u2019 bone forming amongst tumour cells in the medullary cavity, showing appositional deposition (scaffolding) on existing bone trabeculae (\u2018\u2018T\u2019\u2019) (H&E, original magnification 2006). D, Left panel: malignant tumour cells amongst pale eosinophilic osteoid which is partially mineralised (arrow) (H&E, original magnification 4006). Right panel: fine, randomly arborising strands of mineralised osteoid (\u2018\u2018malignant\u2019\u2019 bone) amongst SaOS-2 tumour cells (H&E, original magnification 4006). doi:10.1371/journal.pone.0085128.g002", "width": 944, "height": 692, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84], "c": [85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126], "d": [129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153], "e": [154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 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{"pdf_hash": "4afec7b9cf68130af064da1dfdc0017578436e18", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. (a) X-ray of the abdomen while the patient was standing. An air-fluid level can be seen (white arrow). (b) Computed tomographic scan of the abdomen performed with intravenous contrast material. Part of the mesentery in the middle part of the abdomen is swirled with mesangial thickening, and mesentery and adipose tissue encapsulate mesenteric vessels. Exudation surrounds the mesenteric soft tissue mass in the middle of the abdomen (red arrow) and there are scattered lymph nodes in this mass (blue arrow). Branches of the superior mesenteric artery and tributaries of the superior mesenteric vein in the mesenteric soft tissue mass can be seen (the cavity of all of these vessels is not narrow) (thin white arrow). (c) Stones in the bile duct were taken out after performing endoscopic retrograde cholangiopancreatography. (d) Computed tomographic scan of the abdomen performed with intravenous contrast material, which was performed 4 weeks after the scan shown in panel B, shows a mesenteric soft tissue mass (11.6 6.8 cm). Part of the mesentery in the middle part of the abdomen is swirled with mesangial thickening and increased density of the mesentery. The mesentery and adipose tissue encapsulate mesenteric vessels. The surrounding exudation is more aggravated than previously observed (red arrow). There are scattered lymph nodes in the mesenteric soft tissue mass (blue arrow) and a pseudocapsule has formed around this mass (thick white arrow). Branches of the superior mesenteric artery and tributaries of the superior mesenteric vein in the mesenteric soft tissue mass can be seen (the cavity of all of these vessels is not narrow) (thin white arrow). (e) Computed tomographic scan of the abdomen performed with intravenous contrast material at discharge shows a reduction in size of the mesenteric soft tissue mass (6.8 5.0 cm). Exudation of the mesenteric soft tissue mass is greatly reduced (red arrows) and the pseudocapsule still remains (thick white arrow). 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{"pdf_hash": "977eec40cc10b71857b7b2a670d759de6a38e22a", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "FIGURE 5 Indirect immunofluorescence of Schwann cel l -nerve cell cultures with anti-PG1 monoclonal antibody. Cultures grown in N2 for 4 wk were keep in N2 medium (A) or switched to N2FA medium (B). After 5 d, the cultures were processed for indirect immunofluorescence using the mouse monoclonal ant ibody B3 which was shown to recognize PG1 (see Fig. 4). The nuclear fluorescence in both micrographs is not due to the ant ibody (not shown). Note in the N2FA culture (B) the linear extracellular staining pattern characteristic of Schwann cell basal lamina staining. The inset in B shows an N2FA culture stained with ant icollagen IV antiserum. This antiserum does not stain N2 cultures (not shov :l). Both specimens were prepared for immunofluorescence, photographed, and printed under identical conditions, x 490.", "width": 1290, "height": 886, "subcaptions": {"a": [32, 26, 27, 28, 29, 30, 31], "b": [34, 35, 36, 37, 38, 39, 40, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126]}, "subfigures": [{"id": "af220d8b-dfe4-485b-8dcc-804ec3180482", "label": "a", "points": [[4.1, 2], [4.1, 847.8], [644, 847.8], [644, 2]], "color": "yellow"}, {"id": "e225d5a4-9dfb-4d05-bf6c-01b2ef1d5a08", "label": "b", "points": [[654.2, 851.9], [654.2, 8.2], [1281.9, 8.2], [1281.9, 851.9]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": "Indirect", "start": 9, "end": 17, "id": 2}, {"text": "immunofluorescence", "start": 18, "end": 36, "id": 3}, {"text": "of", "start": 37, "end": 39, "id": 4}, {"text": 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{"pdf_hash": "3b6a2c07026697f84632385692337f389b2bb2f7", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "FIGURE 6. Transverse cross-section through rod area of phantom filled with 124I solution. Images without (A) and with (B) scatter correction are shown. Scatter-corrected image clearly displays ellipsoid deformation.", "width": 782, "height": 360, "subcaptions": {"a": [18, 19, 20, 21], "b": [23, 24, 25, 26]}, "subfigures": [{"id": "908bd95a-9c48-4975-9b82-1d64c47d8b1f", "label": "a", "points": [[88.1, 2.3], [88.1, 330.9], [409.2, 330.9], [409.2, 2.3]], "color": "yellow"}, {"id": "68b72cbb-b389-467e-a4d1-991cfbb1c832", "label": "b", "points": [[420.4, 4.8], [420.4, 332.1], [750.2, 332.1], [750.2, 4.8]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Transverse", "start": 10, "end": 20, "id": 3}, {"text": "cross", "start": 21, "end": 26, "id": 4}, {"text": "-", "start": 26, "end": 27, "id": 5}, {"text": "section", "start": 27, "end": 34, "id": 6}, {"text": "through", "start": 35, "end": 42, "id": 7}, {"text": "rod", "start": 43, "end": 46, "id": 8}, {"text": "area", "start": 47, "end": 51, "id": 9}, {"text": "of", "start": 52, "end": 54, "id": 10}, {"text": "phantom", "start": 55, "end": 62, "id": 11}, {"text": "filled", "start": 63, "end": 69, "id": 12}, {"text": "with", "start": 70, "end": 74, "id": 13}, {"text": "124I", "start": 75, "end": 79, "id": 14}, {"text": "solution", "start": 80, "end": 88, "id": 15}, {"text": ".", "start": 88, "end": 89, "id": 16}, {"text": "Images", "start": 90, "end": 96, "id": 17}, {"text": "without", "start": 97, "end": 104, "id": 18}, {"text": "(", "start": 105, "end": 106, "id": 19}, {"text": "A", "start": 106, "end": 107, "id": 20}, {"text": ")", "start": 107, "end": 108, "id": 21}, {"text": "and", "start": 109, "end": 112, "id": 22}, {"text": "with", "start": 113, "end": 117, "id": 23}, {"text": "(", "start": 118, "end": 119, "id": 24}, {"text": "B", "start": 119, "end": 120, "id": 25}, {"text": ")", "start": 120, "end": 121, "id": 26}, {"text": "scatter", "start": 122, "end": 129, "id": 27}, {"text": "correction", "start": 130, "end": 140, "id": 28}, {"text": "are", "start": 141, "end": 144, "id": 29}, {"text": "shown", "start": 145, "end": 150, "id": 30}, {"text": ".", "start": 150, "end": 151, "id": 31}, {"text": "Scatter", "start": 152, "end": 159, "id": 32}, {"text": "-", "start": 159, "end": 160, "id": 33}, {"text": "corrected", "start": 160, "end": 169, "id": 34}, {"text": "image", "start": 170, "end": 175, "id": 35}, {"text": "clearly", "start": 176, "end": 183, "id": 36}, {"text": "displays", "start": 184, "end": 192, "id": 37}, {"text": "ellipsoid", "start": 193, "end": 202, "id": 38}, {"text": "deformation", "start": 203, "end": 214, "id": 39}, {"text": ".", "start": 214, "end": 215, "id": 40}]}
{"pdf_hash": "1b5ac7e2803305d2570885b403d565406c6d8b5b", "fig_key": "Figure5", "fig_uri": "9-Figure5-1.png", "text": "Figure 5. A non-smoking woman with lung adenocarcinoma in the left upper lobe, where PCR images (A) and pathological picture (D) show that the subtype is exon 21 mutation. CT images (B,C) show a subsolid lump with spiculated margins.", "width": 1100, "height": 878, "subcaptions": {"a": [32, 33, 34, 35, 36, 16, 17, 18, 19, 20, 21, 22, 29, 30, 31], "b": [32, 33, 34, 35, 36, 16, 17, 24, 25, 26, 27, 28, 29, 30, 31], "c": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52]}, "subfigures": [{"id": "b90e08a7-f531-4fe4-a9cc-f89b71100616", "label": "a", "points": [[66, 5.2], [66, 338.9], [330.2, 338.9], [330.2, 5.2]], "color": "yellow"}, {"id": "b67e93f3-fa0f-47dd-9687-b12b730c8c78", "label": "b", "points": [[1093.1, 349.3], [1093.1, 860.2], [24.3, 860.2], [24.3, 349.3]], "color": "springgreen"}, {"id": "2a042115-311c-4f5f-8adf-37a022440f36", "label": "c", "points": [[368.4, 328.4], [368.4, 3.5], [663.8, 3.5], [663.8, 328.4]], "color": "cyan"}, {"id": "60d0550b-2153-40a0-acf5-ae2d948f592f", "label": "c", "points": [[676, 1.7], [676, 338.9], [1093.1, 338.9], [1093.1, 1.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "non", "start": 12, "end": 15, "id": 4}, {"text": "-", "start": 15, "end": 16, "id": 5}, {"text": "smoking", "start": 16, "end": 23, "id": 6}, {"text": "woman", "start": 24, "end": 29, "id": 7}, {"text": "with", "start": 30, "end": 34, "id": 8}, {"text": "lung", "start": 35, "end": 39, "id": 9}, {"text": "adenocarcinoma", "start": 40, "end": 54, "id": 10}, {"text": "in", "start": 55, "end": 57, "id": 11}, {"text": "the", "start": 58, "end": 61, "id": 12}, {"text": "left", "start": 62, "end": 66, "id": 13}, {"text": "upper", "start": 67, "end": 72, "id": 14}, {"text": "lobe", "start": 73, "end": 77, "id": 15}, {"text": ",", "start": 77, "end": 78, "id": 16}, {"text": "where", "start": 79, "end": 84, "id": 17}, {"text": "PCR", "start": 85, "end": 88, "id": 18}, {"text": "images", "start": 89, "end": 95, "id": 19}, {"text": "(", "start": 96, "end": 97, "id": 20}, {"text": "A", "start": 97, "end": 98, "id": 21}, {"text": ")", "start": 98, "end": 99, "id": 22}, {"text": "and", "start": 100, "end": 103, "id": 23}, {"text": "pathological", "start": 104, "end": 116, "id": 24}, {"text": "picture", "start": 117, "end": 124, "id": 25}, {"text": "(", "start": 125, "end": 126, "id": 26}, {"text": "D", "start": 126, "end": 127, "id": 27}, {"text": ")", "start": 127, "end": 128, "id": 28}, {"text": "show", "start": 129, "end": 133, "id": 29}, {"text": "that", "start": 134, "end": 138, "id": 30}, {"text": "the", "start": 139, "end": 142, "id": 31}, {"text": "subtype", "start": 143, "end": 150, "id": 32}, {"text": "is", "start": 151, "end": 153, "id": 33}, {"text": "exon", "start": 154, "end": 158, "id": 34}, {"text": "21", "start": 159, "end": 161, "id": 35}, {"text": "mutation", "start": 162, "end": 170, "id": 36}, {"text": ".", "start": 170, "end": 171, "id": 37}, {"text": "CT", "start": 172, "end": 174, "id": 38}, {"text": "images", "start": 175, "end": 181, "id": 39}, {"text": "(", "start": 182, "end": 183, "id": 40}, {"text": "B", "start": 183, "end": 184, "id": 41}, {"text": ",", "start": 184, "end": 185, "id": 42}, {"text": "C", "start": 185, "end": 186, "id": 43}, {"text": ")", "start": 186, "end": 187, "id": 44}, {"text": "show", "start": 188, "end": 192, "id": 45}, {"text": "a", "start": 193, "end": 194, "id": 46}, {"text": "subsolid", "start": 195, "end": 203, "id": 47}, {"text": "lump", "start": 204, "end": 208, "id": 48}, {"text": "with", "start": 209, "end": 213, "id": 49}, {"text": "spiculated", "start": 214, "end": 224, "id": 50}, {"text": "margins", "start": 225, "end": 232, "id": 51}, {"text": ".", "start": 232, "end": 233, "id": 52}]}
{"pdf_hash": "fc628591e1f01f38f0ec3fa190325a230d446a01", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Initial T 1 -weighted magnetic resonance (MR) images with gadolinium showing an enhanced tumor measuring 5 cm in diameter attached to the left frontal base on the axial image (A), and on the coronal image (B). Follow-up T 1 -weighted MR images with gadolinium showing remarkable regression of the tumor at 2 years 9 months after the initial presentation (C, D).", "width": 664, "height": 712, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 46], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 39, 40, 41, 42, 43, 44, 45, 46], "c": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77]}, "subfigures": [{"id": "cbbc4b1a-96a8-40c2-a9a8-7885673584de", "label": "a", "points": [[4.8, 6.1], [4.8, 361.7], [319.4, 361.7], [319.4, 6.1]], "color": "yellow"}, {"id": "46f8bbac-6b58-4d73-88be-18e14137b393", "label": "b", "points": [[333.1, 4], [333.1, 363.8], [658.2, 363.8], [658.2, 4]], "color": "cyan"}, {"id": "d02ed3e9-d198-4a96-87fa-9c378a51d31e", "label": "c", "points": [[6.9, 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{"pdf_hash": "2a6ed27cf4b394b4b665b623df51184f3c61c7bf", "fig_key": "Figure8", "fig_uri": "4-Figure8-1.png", "text": "Fig. 8 Urachal carcinoma with invasion of the small bowel. a Abdominal radiograph after instillation of contrast into the bladder shows a vesicoenteric fistula (arrow) with filling of multiple small bowel loops. b Axial CT image shows both enteric contrast and gas within the tumor", "width": 1026, "height": 652, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "b": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "d55eb3fd-2fec-428c-89be-9be9b6e6735c", "label": "a", "points": [[0, 4.9], [0, 648.4], [539.8, 648.4], [539.8, 4.9]], "color": "yellow"}, {"id": "c31f4bec-9527-4389-9ef1-e0fbbeeaa685", "label": "b", "points": [[548.8, 307.3], [548.8, 648.8], [1023.6, 648.8], [1023.6, 307.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "8", "start": 5, "end": 6, "id": 2}, {"text": "Urachal", "start": 7, "end": 14, "id": 3}, {"text": "carcinoma", "start": 15, "end": 24, "id": 4}, {"text": "with", "start": 25, "end": 29, "id": 5}, {"text": "invasion", "start": 30, "end": 38, "id": 6}, {"text": "of", "start": 39, "end": 41, "id": 7}, {"text": "the", "start": 42, "end": 45, "id": 8}, {"text": "small", "start": 46, "end": 51, "id": 9}, {"text": "bowel", "start": 52, "end": 57, "id": 10}, {"text": ".", "start": 57, "end": 58, "id": 11}, {"text": "a", "start": 59, "end": 60, "id": 12}, {"text": "Abdominal", "start": 61, "end": 70, "id": 13}, {"text": "radiograph", "start": 71, "end": 81, "id": 14}, {"text": "after", "start": 82, "end": 87, "id": 15}, {"text": "instillation", "start": 88, "end": 100, "id": 16}, {"text": "of", "start": 101, "end": 103, "id": 17}, {"text": "contrast", "start": 104, "end": 112, "id": 18}, {"text": "into", "start": 113, "end": 117, "id": 19}, {"text": "the", "start": 118, "end": 121, "id": 20}, {"text": "bladder", "start": 122, "end": 129, "id": 21}, {"text": "shows", "start": 130, "end": 135, "id": 22}, {"text": "a", "start": 136, "end": 137, "id": 23}, {"text": "vesicoenteric", "start": 138, "end": 151, "id": 24}, {"text": "fistula", "start": 152, "end": 159, "id": 25}, {"text": "(", "start": 160, "end": 161, "id": 26}, {"text": "arrow", "start": 161, "end": 166, "id": 27}, {"text": ")", "start": 166, "end": 167, "id": 28}, {"text": "with", "start": 168, "end": 172, "id": 29}, {"text": "filling", "start": 173, "end": 180, "id": 30}, {"text": "of", "start": 181, "end": 183, "id": 31}, {"text": "multiple", "start": 184, "end": 192, "id": 32}, {"text": "small", "start": 193, "end": 198, "id": 33}, {"text": "bowel", "start": 199, "end": 204, "id": 34}, {"text": "loops", "start": 205, "end": 210, "id": 35}, {"text": ".", "start": 210, "end": 211, "id": 36}, {"text": "b", "start": 212, "end": 213, "id": 37}, {"text": "Axial", "start": 214, "end": 219, "id": 38}, {"text": "CT", "start": 220, "end": 222, "id": 39}, {"text": "image", "start": 223, "end": 228, "id": 40}, {"text": "shows", "start": 229, "end": 234, "id": 41}, {"text": "both", "start": 235, "end": 239, "id": 42}, {"text": "enteric", "start": 240, "end": 247, "id": 43}, {"text": "contrast", "start": 248, "end": 256, "id": 44}, {"text": "and", "start": 257, "end": 260, "id": 45}, {"text": "gas", "start": 261, "end": 264, "id": 46}, {"text": "within", "start": 265, "end": 271, "id": 47}, {"text": "the", "start": 272, "end": 275, "id": 48}, {"text": "tumor", "start": 276, "end": 281, "id": 49}]}
{"pdf_hash": "db8426e3f4e9618f6cbea76c5bd2dbc1ecde01f7", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 Incomplete treatment due to extrahepatic tumor blood supply. Axial contrast-enhanced CT scan (a) demonstrates segment 7 hepatocellular carcinoma (arrowheads). Arteriogram (b) shows hypervascular tumor (arrows). However, note absent perfusion along posteromedial margin (arrowheads), which was unnoticed prior to 90 Y RE. Posttreatment axial contrast-enhanced CT scan (c) displays partial tumor response, with persistent viable tumor enhancement (asterisk). 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{"pdf_hash": "af05b54a35f366aaa4de58f58feaaaaa3854551d", "fig_key": "Figure10", "fig_uri": "7-Figure10-1.png", "text": "Figure 10 (bottom): Aborted male fetus at 20 weeks of gestation with congenital high airway obstruction syndrome: Findings: Contrast radiograph of upper airways in (a) lateral and (b) antero-posterior views depicting normal contrast filling of the pharynx with abrupt distal cut off (yellow arrow). Technique: Contrast (Iohexol). KonicaMinolta Aero DR System. 53kV, 6mAS.", "width": 1400, "height": 908, "subcaptions": {"a": [29, 30, 31, 32], "b": [34, 35, 36, 37, 38, 39]}, "subfigures": [{"id": "90e512c5-2bd5-4a17-b451-5e823c97a255", "label": "a", "points": [[5.1, 1.9], [5.1, 891], [679.6, 891], [679.6, 1.9]], "color": "yellow"}, {"id": "7c0e45b7-94f6-44ca-9ce2-d1830b3aa386", "label": "b", "points": [[699.5, 4.1], [699.5, 904.3], [1385.1, 904.3], [1385.1, 4.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "10", "start": 7, "end": 9, "id": 1}, {"text": "(", "start": 10, "end": 11, "id": 2}, {"text": "bottom", "start": 11, "end": 17, "id": 3}, {"text": ")", "start": 17, "end": 18, "id": 4}, {"text": ":", "start": 18, "end": 19, "id": 5}, {"text": "Aborted", "start": 20, "end": 27, "id": 6}, {"text": "male", "start": 28, "end": 32, "id": 7}, {"text": "fetus", "start": 33, "end": 38, "id": 8}, {"text": "at", "start": 39, "end": 41, "id": 9}, {"text": "20", "start": 42, "end": 44, "id": 10}, {"text": "weeks", "start": 45, "end": 50, "id": 11}, {"text": "of", "start": 51, "end": 53, "id": 12}, {"text": "gestation", "start": 54, "end": 63, "id": 13}, {"text": "with", "start": 64, "end": 68, "id": 14}, {"text": "congenital", "start": 69, "end": 79, "id": 15}, {"text": "high", "start": 80, "end": 84, "id": 16}, {"text": "airway", "start": 85, "end": 91, "id": 17}, {"text": "obstruction", "start": 92, "end": 103, "id": 18}, {"text": "syndrome", "start": 104, "end": 112, "id": 19}, {"text": ":", "start": 112, "end": 113, "id": 20}, {"text": "Findings", "start": 114, "end": 122, "id": 21}, {"text": ":", "start": 122, "end": 123, "id": 22}, {"text": "Contrast", "start": 124, "end": 132, "id": 23}, {"text": "radiograph", "start": 133, "end": 143, "id": 24}, {"text": "of", "start": 144, "end": 146, "id": 25}, {"text": "upper", "start": 147, "end": 152, "id": 26}, {"text": "airways", "start": 153, "end": 160, "id": 27}, {"text": "in", "start": 161, "end": 163, "id": 28}, {"text": "(", "start": 164, "end": 165, "id": 29}, {"text": "a", "start": 165, "end": 166, "id": 30}, {"text": ")", "start": 166, "end": 167, "id": 31}, {"text": "lateral", "start": 168, "end": 175, "id": 32}, {"text": "and", "start": 176, "end": 179, "id": 33}, {"text": "(", "start": 180, "end": 181, "id": 34}, {"text": "b", "start": 181, "end": 182, "id": 35}, {"text": ")", "start": 182, "end": 183, "id": 36}, {"text": "antero", "start": 184, "end": 190, "id": 37}, {"text": "-", "start": 190, "end": 191, "id": 38}, {"text": "posterior", "start": 191, "end": 200, "id": 39}, {"text": "views", "start": 201, "end": 206, "id": 40}, {"text": "depicting", "start": 207, "end": 216, "id": 41}, {"text": "normal", "start": 217, "end": 223, "id": 42}, {"text": "contrast", "start": 224, "end": 232, "id": 43}, {"text": "filling", "start": 233, "end": 240, "id": 44}, {"text": "of", "start": 241, "end": 243, "id": 45}, {"text": "the", "start": 244, "end": 247, "id": 46}, {"text": "pharynx", "start": 248, "end": 255, "id": 47}, {"text": "with", "start": 256, "end": 260, "id": 48}, {"text": "abrupt", "start": 261, "end": 267, "id": 49}, {"text": "distal", "start": 268, "end": 274, "id": 50}, {"text": "cut", "start": 275, "end": 278, "id": 51}, {"text": "off", "start": 279, "end": 282, "id": 52}, {"text": "(", "start": 283, "end": 284, "id": 53}, {"text": "yellow", "start": 284, "end": 290, "id": 54}, {"text": "arrow", "start": 291, "end": 296, "id": 55}, {"text": ")", "start": 296, "end": 297, "id": 56}, {"text": ".", "start": 297, "end": 298, "id": 57}, {"text": "Technique", "start": 299, "end": 308, "id": 58}, {"text": ":", "start": 308, "end": 309, "id": 59}, {"text": "Contrast", "start": 310, "end": 318, "id": 60}, {"text": "(", "start": 319, "end": 320, "id": 61}, {"text": "Iohexol", "start": 320, "end": 327, "id": 62}, {"text": ")", "start": 327, "end": 328, "id": 63}, {"text": ".", "start": 328, "end": 329, "id": 64}, {"text": "KonicaMinolta", "start": 330, "end": 343, "id": 65}, {"text": "Aero", "start": 344, "end": 348, "id": 66}, {"text": "DR", "start": 349, "end": 351, "id": 67}, {"text": "System", "start": 352, "end": 358, "id": 68}, {"text": ".", "start": 358, "end": 359, "id": 69}, {"text": "53kV", "start": 360, "end": 364, "id": 70}, {"text": ",", "start": 364, "end": 365, "id": 71}, {"text": "6mAS", "start": 366, "end": 370, "id": 72}, {"text": ".", "start": 370, "end": 371, "id": 73}]}
{"pdf_hash": "85bef3ab19354a8a413880cea4bb2ab187864a34", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "FIGURE 3 | The two fiber tracts, CST and Fminor, subject to quantitative analysis. (A) The corticospinal tract (CST ) in one of the subjects, extracted by using one ROI (pink surface) on the cerebral peduncle at the level of the decussation of the superior cerebellar peduncle (DSCP) and one ROI (green surface) at the central sulcus (CS) after the bifurcation to the motor and sensory cortex. 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{"pdf_hash": "a14a98d5f0c4774ab9efdfc5fb8e635d663cea72", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. Selected magnifications of nuclear sections. Exponential (a) and stationary (b) phase nuclei are depicted. The arrows indicate the presence of heterochromatin, the nucleoli (No) are also indicated.", "width": 466, "height": 802, "subcaptions": {"a": [10, 11, 12, 13], "b": [15, 16, 17, 18]}, "subfigures": [{"id": "95d5c713-4bfa-4696-8d15-2cb92e4055d0", "label": "a", "points": [[0.5, 31], [0.5, 373], [463.5, 373], [463.5, 31]], "color": "yellow"}, {"id": "e014f53a-3f3c-4009-b0a6-b5fe181ced76", "label": "b", "points": [[2.5, 424], [2.5, 762], [461.5, 762], [461.5, 424]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Selected", "start": 8, "end": 16, "id": 4}, {"text": "magnifications", "start": 17, "end": 31, "id": 5}, {"text": "of", "start": 32, "end": 34, "id": 6}, {"text": "nuclear", "start": 35, "end": 42, "id": 7}, {"text": "sections", "start": 43, "end": 51, "id": 8}, {"text": ".", "start": 51, "end": 52, "id": 9}, {"text": "Exponential", "start": 53, "end": 64, "id": 10}, {"text": "(", "start": 65, "end": 66, "id": 11}, {"text": "a", "start": 66, "end": 67, "id": 12}, {"text": ")", "start": 67, "end": 68, "id": 13}, {"text": "and", "start": 69, "end": 72, "id": 14}, {"text": "stationary", "start": 73, "end": 83, "id": 15}, {"text": "(", "start": 84, "end": 85, "id": 16}, {"text": "b", "start": 85, "end": 86, "id": 17}, {"text": ")", "start": 86, "end": 87, "id": 18}, {"text": "phase", "start": 88, "end": 93, "id": 19}, {"text": "nuclei", "start": 94, "end": 100, "id": 20}, {"text": "are", "start": 101, "end": 104, "id": 21}, {"text": "depicted", "start": 105, "end": 113, "id": 22}, {"text": ".", "start": 113, "end": 114, "id": 23}, {"text": "The", "start": 115, "end": 118, "id": 24}, {"text": "arrows", "start": 119, "end": 125, "id": 25}, {"text": "indicate", "start": 126, "end": 134, "id": 26}, {"text": "the", "start": 135, "end": 138, "id": 27}, {"text": "presence", "start": 139, "end": 147, "id": 28}, {"text": "of", "start": 148, "end": 150, "id": 29}, {"text": "heterochromatin", "start": 151, "end": 166, "id": 30}, {"text": ",", "start": 166, "end": 167, "id": 31}, {"text": "the", "start": 168, "end": 171, "id": 32}, {"text": "nucleoli", "start": 172, "end": 180, "id": 33}, {"text": "(", "start": 181, "end": 182, "id": 34}, {"text": "No", "start": 182, "end": 184, "id": 35}, {"text": ")", "start": 184, "end": 185, "id": 36}, {"text": "are", "start": 186, "end": 189, "id": 37}, {"text": "also", "start": 190, "end": 194, "id": 38}, {"text": "indicated", "start": 195, "end": 204, "id": 39}, {"text": ".", "start": 204, "end": 205, "id": 40}]}
{"pdf_hash": "b10a6fbdd832ce0933366e3129ed9b8df19988b6", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 (Left panel): CT images on dorsal plane: 1) Cerebrum; 8) Maxillary bone; 9) Ethmoid; 16) Nasal septum; 17) Septum of the maxillary sinus; 19) Rostral maxillary sinus; 20) Caudal maxillary sinus; 23) Ventral nasal concha; 26) Common nasal meatus; 28) Infraorbital canal. (Right panel): CT image on median sagittal plane: 1) Dorsal nasal meatus; 2) Ventral nasal meatus; 3) Middle nasal meatus; 4) Conchofrontal sinus; 7) Sphenopalatine sinus; 8) Dorsal nasal concha; 9) Ventral nasal concha; 12) Nasopharynx; 14) Ethmoid; 16) Nasal bone; 17) Frontal bone; 25) Cerebrum; 26) Pre-sphenoid", "width": 962, "height": 358, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67], "b": [68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145]}, 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47, "id": 13}, {"text": "1", "start": 48, "end": 49, "id": 14}, {"text": ")", "start": 49, "end": 50, "id": 15}, {"text": "Cerebrum", "start": 51, "end": 59, "id": 16}, {"text": ";", "start": 59, "end": 60, "id": 17}, {"text": "8)", "start": 61, "end": 63, "id": 18}, {"text": "Maxillary", "start": 64, "end": 73, "id": 19}, {"text": "bone", "start": 74, "end": 78, "id": 20}, {"text": ";", "start": 78, "end": 79, "id": 21}, {"text": "9", "start": 80, "end": 81, "id": 22}, {"text": ")", "start": 81, "end": 82, "id": 23}, {"text": "Ethmoid", "start": 83, "end": 90, "id": 24}, {"text": ";", "start": 90, "end": 91, "id": 25}, {"text": "16", "start": 92, "end": 94, "id": 26}, {"text": ")", "start": 94, "end": 95, "id": 27}, {"text": "Nasal", "start": 96, "end": 101, "id": 28}, {"text": "septum", "start": 102, "end": 108, "id": 29}, {"text": ";", "start": 108, "end": 109, "id": 30}, {"text": "17", "start": 110, "end": 112, "id": 31}, {"text": ")", "start": 112, "end": 113, "id": 32}, {"text": 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{"pdf_hash": "342ec642584919f2f6cb660b30ba22d74d93fd6b", "fig_key": "Figure7", "fig_uri": "10-Figure7-1.png", "text": "Figure 7. Electron micrographs demonstrating the prevention of perivascular edema, demyelination/axon loss, and neuronal apoptosis/necrosis in the rat EAE model by PMSC and P + C + A treatment. (A,B) Normal control rats. (A) normal myelinated axons exhibiting dark, ring-shaped myelin sheaths surrounding axons, (B) normal neuronal nuclei with uncondensed chromatin. (C\u2013G) Vehicle-treated EAE rats at 3 weeks pi. (C) myelin sheath displaying splitting, vacuoles, loose and fused changes, and shrunken, atrophied axons, (D,E) tissue edema (D) and severe blood vessel leakage (E, arrow) detected in the extracellular space surrounding the vessels, (F) a neuron showing signs of apoptosis with a shrunken nucleus and condensed, fragmented, and marginated nuclear chromatin, (G) an extravasated inflammatory cell in tissue edema. (H\u2013K) PMSC- (H,I) and P + C + A- (J,K) treated EAE rats at 3 weeks pi. Myelin sheath splitting, axonal loss, and perivascular edema were reduced, and neuron nuclei displayed relatively normal morphology. (L\u2013N) Vehicle-treated EAE rats at 8 weeks pi. Many myelin lamellae were still undergoing vesicular disintegration and demyelination (L), with some fibers being completely lost or only showing an empty circle of remaining myelin (arrow in L). 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{"pdf_hash": "4c1c2e376d6d76e629bd27c61c9162ec80e7789e", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. PPT1 and Rab3IP are detected in cilia. MEFs were immunostained by anti-acetylated tubulin antibodies, using anti-mouse Alexa 488 as secondary antibodies (A), anti-PPT1 antibodies using anti rabbit Alexa 647 as secondary antibodies (B) and anti-Rab3IP antibodies using anti-goat CY3 as secondary antibodies (C). Both PPT1 and Rab3IP colocalize with acetylated tubulin (D,F) and with each other (E,G). Nuclei are stained by DAPI represented by the blue channel. Scale bar 5mm. 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{"pdf_hash": "6f5806e3a3674815aabeec9a868d836be3d463bf", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Nuclear import of the C domain of E2 in in vitro assays in digitoninpermeabilized cells. Digitonin-permeabilized HeLa cells were incubated with either GST-cE2 (A and B), or GST-NLS 16L1 (C and D), or GST, as a negative control (E and F) in the presence of either only transport buffer (A, C and E) or HeLa cytosol (B, D and F). Nuclear localization of the GST fusion proteins was detected by immunofluorescence microscopy with an anti-GST antibody. 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{"pdf_hash": "e9e5c079acacecfbf507f7434f0a20ca567137a3", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. (A\u2013B) Axial T1W MR Images shows corresponding hypointense lesion (star) in the pancreas. Lesion appears heterogeneous on T2W images and demonstrates intermediate signal intensity; (C) Axial post contrast fat suppressed T1W image shows mild enhancement; (D) Extensive mesenteric lymphadenopathy surrounding SMA (arrows).", "width": 1260, "height": 830, "subcaptions": {"a": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "b": [50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "ef85c915-0496-4b60-8a1f-bafd90cc19c3", "label": "a", "points": [[30.9, 3.7], [30.9, 403.7], [626.1, 403.7], [626.1, 3.7]], "color": "yellow"}, {"id": "ad69a5f3-5558-4c04-aee5-9b746fee3668", "label": "a", "points": [[632, 1.7], [632, 401.7], [1221.2, 401.7], [1221.2, 1.7]], "color": "cyan"}, {"id": "696c44d1-ba15-4d8e-a2a5-42c17128f50c", "label": "b", "points": [[34.9, 409.7], [34.9, 793.8], [610.1, 793.8], [610.1, 409.7]], "color": "magenta"}, {"id": "b0d5ba38-7a09-4fe8-9cba-04308311d75f", "label": "c", "points": [[626.1, 413.7], [626.1, 797.8], [1223.2, 797.8], [1223.2, 413.7]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": "\u2013", "start": 10, "end": 11, "id": 6}, {"text": "B", "start": 11, "end": 12, "id": 7}, {"text": ")", "start": 12, "end": 13, "id": 8}, {"text": "Axial", "start": 14, "end": 19, "id": 9}, {"text": "T1W", "start": 20, "end": 23, "id": 10}, {"text": "MR", "start": 24, "end": 26, "id": 11}, {"text": "Images", "start": 27, "end": 33, "id": 12}, {"text": "shows", "start": 34, "end": 39, "id": 13}, {"text": "corresponding", "start": 40, "end": 53, "id": 14}, {"text": "hypointense", "start": 54, "end": 65, "id": 15}, {"text": "lesion", "start": 66, "end": 72, "id": 16}, {"text": "(", "start": 73, "end": 74, "id": 17}, {"text": "star", "start": 74, "end": 78, "id": 18}, {"text": ")", "start": 78, "end": 79, "id": 19}, {"text": "in", "start": 80, "end": 82, "id": 20}, {"text": "the", "start": 83, "end": 86, "id": 21}, {"text": "pancreas", "start": 87, "end": 95, "id": 22}, {"text": ".", "start": 95, "end": 96, "id": 23}, {"text": "Lesion", "start": 97, "end": 103, "id": 24}, {"text": "appears", "start": 104, "end": 111, "id": 25}, {"text": "heterogeneous", "start": 112, "end": 125, "id": 26}, {"text": "on", "start": 126, "end": 128, "id": 27}, {"text": "T2W", "start": 129, "end": 132, "id": 28}, {"text": "images", "start": 133, "end": 139, "id": 29}, {"text": "and", "start": 140, "end": 143, "id": 30}, {"text": "demonstrates", "start": 144, "end": 156, "id": 31}, {"text": "intermediate", "start": 157, "end": 169, "id": 32}, {"text": "signal", "start": 170, "end": 176, "id": 33}, {"text": "intensity", "start": 177, "end": 186, "id": 34}, {"text": ";", "start": 186, "end": 187, "id": 35}, {"text": "(", "start": 188, "end": 189, "id": 36}, {"text": "C", "start": 189, "end": 190, "id": 37}, {"text": ")", "start": 190, "end": 191, "id": 38}, {"text": "Axial", "start": 192, "end": 197, "id": 39}, {"text": "post", "start": 198, "end": 202, "id": 40}, {"text": "contrast", "start": 203, "end": 211, "id": 41}, {"text": "fat", "start": 212, "end": 215, "id": 42}, {"text": "suppressed", "start": 216, "end": 226, "id": 43}, {"text": "T1W", "start": 227, "end": 230, "id": 44}, {"text": "image", "start": 231, "end": 236, "id": 45}, {"text": "shows", "start": 237, "end": 242, "id": 46}, {"text": "mild", "start": 243, "end": 247, "id": 47}, {"text": "enhancement", "start": 248, "end": 259, "id": 48}, {"text": ";", "start": 259, "end": 260, "id": 49}, {"text": "(", "start": 261, "end": 262, "id": 50}, {"text": "D", "start": 262, "end": 263, "id": 51}, {"text": ")", "start": 263, "end": 264, "id": 52}, {"text": "Extensive", "start": 265, "end": 274, "id": 53}, {"text": "mesenteric", "start": 275, "end": 285, "id": 54}, {"text": "lymphadenopathy", "start": 286, "end": 301, "id": 55}, {"text": "surrounding", "start": 302, "end": 313, "id": 56}, {"text": "SMA", "start": 314, "end": 317, "id": 57}, {"text": "(", "start": 318, "end": 319, "id": 58}, {"text": "arrows", "start": 319, "end": 325, "id": 59}, {"text": ")", "start": 325, "end": 326, "id": 60}, {"text": ".", "start": 326, "end": 327, "id": 61}]}
{"pdf_hash": "9d1619c18c68ce4c2c859cd6c5913977c7b1fc33", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3: (a)-(c) Head CT images showing acute epidural hematoma at the left occipital region prior to and after surgery. (a) Head CT images prior to surgery; bleeding volume was approximately 13 mL. (b) Head CT images 3 days after surgery; hematoma volume was obviously reduced. Arrows indicate the site of hematoma and drainage tube. 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{"pdf_hash": "609bf3f96c6378052a81660fb8c9b3ab18c9047f", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5 Visualization of Xanthomonas oryzae pv. oryzae (Xoo) in rice plants. (A, B) Transverse leaf sections of rice infected with Xoo strain PXO99 expressing the green fluorescence of rice cultivar TP309 (susceptible) (A) and TP309-XA21 (resistant) (B). Images were observed with excitation from 450 to 490 nm and emitted light collected at 520 nm at 40\u00a5 magnification using a Zeiss Axiophot fluorescence microscope, 12 days after inoculation. The bars in (A) and (B) represent 50 mm. (C) Scanning electron micrograph of Xoo cells in the xylem vessel of a rice leaf. (D) Close-up of Xoo-infected rice leaf. Bacterial cells fill the xylem vessels and ooze out at hydathodes, forming beads or strands of exudate on the leaf surface, a characteristic sign of the disease. Photographs in (A) and (B) courtesy of S. W. Han (reprinted from BMC Microbiol. 2008; 8: 164). Photograph in (C) courtesy of J. Leach (reprinted from Mol. Plant Pathol. 2006; 7(5): 303-324). Photograph in (D) courtesy of the Bureau of Rice Research and Development, Thailand (http://www.brrd.in.th).", "width": 896, "height": 792, "subcaptions": {"a": [17, 18, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87], "b": [17, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87], "c": [102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119], "d": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": 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{"pdf_hash": "860749e2c246a5321b4fbbbe7326940abb4fc298", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Sagittal and frontal T1 MRI before (A-1 and A-2), and after treatment with Cabergoline (B-1 and B-2). notes: MRI of the brain and pituitary gland showed enormous invasive tumor mass lesion is mainly solid with two cystic components at sellar, infra-sellar, and supra-sellar area measures 6.5 \u00d7 5.7 \u00d7 5.9 cm in its anterior-posterior, transverse, craniocaudal dimensions respectively. The mass displaced the optic chiasm superiorly. Anterior portion shows retrochiasmatic component which is lobulated and shows a small to medium size lobule extending posteriorly to the left Cp angle (compressing the the left trigeminal nerve), with another small lobule extending posteriorly to the left orbit through the superior orbit fissure. The two cystic components are noted at the hypothalmic and third ventricle with fluid level (evidence of intra-lesional hemorrhage of the posterior extension of this mass along the left tentorial leaflet and adjacent left lateral border of the brainstem), likely representing pituitary apoplexy.", "width": 1014, "height": 764, "subcaptions": {"a": [8, 9, 10, 11, 12, 13], "b": [16, 20, 21, 22, 23, 24]}, "subfigures": [{"id": "ed93ec40-cd4a-425b-b1a4-82ed53a24875", "label": "a", "points": [[5.1, 0.5], [5.1, 394.6], [504.9, 394.6], [504.9, 0.5]], "color": "yellow"}, {"id": "f838eabd-e4b3-443d-9252-f06b21f87e88", "label": "a", "points": [[6.7, 404.2], [6.7, 751.9], [504.9, 751.9], [504.9, 404.2]], "color": "cyan"}, {"id": "12251dba-606e-4da5-861a-4fd623bfe59f", "label": "b", "points": [[512.9, 3.7], [512.9, 388.2], [1004.7, 388.2], [1004.7, 3.7]], "color": "magenta"}, {"id": "f9d2498b-e827-40af-aa6f-dc8f00f2cf12", "label": "b", "points": [[511.3, 404.2], [511.3, 758.3], [1004.7, 758.3], 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{"pdf_hash": "f42a4490971cb4b3ef8edd12bb29a76f0bbbd33c", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 - Preoperative transesophageal echocardiography images. (Midesophageal four chamber view). (LA = left atrium; LV = left ventricle; RA = right atrium; RV = right ventricle; IVS = interventricular septum) A) Systolic anterior motion: during systole (note the white arrow in the ECG trace) the anterior mitral leaflet can be seen kinked at the mid portion, bended into the left ventricular outflow tract (yellow arrow), causing left ventricular outflow tract obstruction. There is also loss of mitral leaflets coaptation. B) Through the resultant interleaflet gap a jet of severe mitral regurgitation is evidenced by color Doppler. 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{"pdf_hash": "927e57358c93a41d8d5f382ca68c5ba066b1a54a", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 \u2013 (A) MRI evidences triangular fibrocartilage lesion; (B) edema on the ulna head; and (C) semilunar edema.", "width": 1132, "height": 384, "subcaptions": {"a": [4, 5, 6, 9, 10, 11], "b": [13, 14, 15, 16, 17, 18, 19, 20], "c": [23, 24, 25, 26, 27]}, "subfigures": [{"id": "752d71b5-ca08-4baa-bcdf-5b18474d4fca", "label": "a", "points": [[39.3, 8.9], [39.3, 350.5], [377.3, 350.5], [377.3, 8.9]], "color": "yellow"}, {"id": "f5b76b87-034e-45d8-ad95-147e6164a146", "label": "b", "points": [[400.6, 346.9], [400.6, 1.8], [736.8, 1.8], [736.8, 346.9]], "color": "cyan"}, {"id": "a8cf4106-0bde-4550-bcb1-29142d2e18b9", "label": "c", "points": [[758.3, 0], [758.3, 346.9], [1094.5, 346.9], [1094.5, 0]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "(", "start": 9, "end": 10, "id": 4}, {"text": "A", "start": 10, "end": 11, "id": 5}, {"text": ")", "start": 11, "end": 12, "id": 6}, {"text": "MRI", "start": 13, "end": 16, "id": 7}, {"text": "evidences", "start": 17, "end": 26, "id": 8}, {"text": "triangular", "start": 27, "end": 37, "id": 9}, {"text": "fibrocartilage", "start": 38, "end": 52, "id": 10}, {"text": "lesion", "start": 53, "end": 59, "id": 11}, {"text": ";", "start": 59, "end": 60, "id": 12}, {"text": "(", "start": 61, "end": 62, "id": 13}, {"text": "B", "start": 62, "end": 63, "id": 14}, {"text": ")", "start": 63, "end": 64, "id": 15}, {"text": "edema", "start": 65, "end": 70, "id": 16}, {"text": "on", "start": 71, "end": 73, "id": 17}, {"text": "the", "start": 74, "end": 77, "id": 18}, {"text": "ulna", "start": 78, "end": 82, "id": 19}, {"text": "head", "start": 83, "end": 87, "id": 20}, {"text": ";", "start": 87, "end": 88, "id": 21}, {"text": "and", "start": 89, "end": 92, "id": 22}, {"text": "(", "start": 93, "end": 94, "id": 23}, {"text": "C", "start": 94, "end": 95, "id": 24}, {"text": ")", "start": 95, "end": 96, "id": 25}, {"text": "semilunar", "start": 97, "end": 106, "id": 26}, {"text": "edema", "start": 107, "end": 112, "id": 27}, {"text": ".", "start": 112, "end": 113, "id": 28}]}
{"pdf_hash": "fe58c4733c346d69148537294101ccd4990ca15b", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 T1-weighted MR images after gadolinium contrast administration. (a) On sagittal and (b) axial views, the mass exhibited marked ringlike enhancement and a regular margin. Axial imaging showed the cervical spinal cord to be displaced posterolaterally to the right by the tumour", "width": 634, "height": 1486, "subcaptions": {"a": [10, 11, 12, 14], "b": [16, 17, 18, 19, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "24e683ba-4abf-4afe-9f8a-73e87e5c7230", "label": "a", "points": [[2, 22.9], [2, 971.3], [632, 971.3], [632, 22.9]], "color": "yellow"}, {"id": "4e040c2f-711d-4914-b0c5-54fabddb89e1", "label": "b", "points": [[1, 1043.9], [1, 1483.6], [630, 1483.6], [630, 1043.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "T1-weighted", "start": 9, "end": 20, "id": 2}, {"text": "MR", "start": 21, "end": 23, "id": 3}, {"text": "images", "start": 24, "end": 30, "id": 4}, {"text": "after", "start": 31, "end": 36, "id": 5}, {"text": "gadolinium", "start": 37, "end": 47, "id": 6}, {"text": "contrast", "start": 48, "end": 56, "id": 7}, {"text": "administration", "start": 57, "end": 71, "id": 8}, {"text": ".", "start": 71, "end": 72, "id": 9}, {"text": "(", "start": 73, "end": 74, "id": 10}, {"text": "a", "start": 74, "end": 75, "id": 11}, {"text": ")", "start": 75, "end": 76, "id": 12}, {"text": "On", "start": 77, "end": 79, "id": 13}, {"text": "sagittal", "start": 80, "end": 88, "id": 14}, {"text": "and", "start": 89, "end": 92, "id": 15}, {"text": "(", "start": 93, "end": 94, "id": 16}, {"text": "b", "start": 94, "end": 95, "id": 17}, {"text": ")", "start": 95, "end": 96, "id": 18}, {"text": "axial", "start": 97, "end": 102, "id": 19}, {"text": "views", "start": 103, "end": 108, "id": 20}, {"text": ",", "start": 108, "end": 109, "id": 21}, {"text": "the", "start": 110, "end": 113, "id": 22}, {"text": "mass", "start": 114, "end": 118, "id": 23}, {"text": "exhibited", "start": 119, "end": 128, "id": 24}, {"text": "marked", "start": 129, "end": 135, "id": 25}, {"text": "ringlike", "start": 136, "end": 144, "id": 26}, {"text": "enhancement", "start": 145, "end": 156, "id": 27}, {"text": "and", "start": 157, "end": 160, "id": 28}, {"text": "a", "start": 161, "end": 162, "id": 29}, {"text": "regular", "start": 163, "end": 170, "id": 30}, {"text": "margin", "start": 171, "end": 177, "id": 31}, {"text": ".", "start": 177, "end": 178, "id": 32}, {"text": "Axial", "start": 179, "end": 184, "id": 33}, {"text": "imaging", "start": 185, "end": 192, "id": 34}, {"text": "showed", "start": 193, "end": 199, "id": 35}, {"text": "the", "start": 200, "end": 203, "id": 36}, {"text": "cervical", "start": 204, "end": 212, "id": 37}, {"text": "spinal", "start": 213, "end": 219, "id": 38}, {"text": "cord", "start": 220, "end": 224, "id": 39}, {"text": "to", "start": 225, "end": 227, "id": 40}, {"text": "be", "start": 228, "end": 230, "id": 41}, {"text": "displaced", "start": 231, "end": 240, "id": 42}, {"text": "posterolaterally", "start": 241, "end": 257, "id": 43}, {"text": "to", "start": 258, "end": 260, "id": 44}, {"text": "the", "start": 261, "end": 264, "id": 45}, {"text": "right", "start": 265, "end": 270, "id": 46}, {"text": "by", "start": 271, "end": 273, "id": 47}, {"text": "the", "start": 274, "end": 277, "id": 48}, {"text": "tumour", "start": 278, "end": 284, "id": 49}]}
{"pdf_hash": "3e1a45d5831257ae3ed16cb8a88c566c791f58e5", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Figure 1 MRI perfusion scan at baseline and follow-up in one patient treated with VEGF-A 165 gene transfer followed by G-CSF. The recordings were performed 20 s after contrast infusion, demonstrating poor perfusion with no contrast enhancement in the lateral wall (black arrows), moderate perfusion with attenuated enhancement (white arrows) in the inferior wall, and normal perfusion in the anterior wall (transparent arrows).", "width": 1378, "height": 720, "subcaptions": {"a": [0]}, "subfigures": [{"id": "9b771d4e-9bbe-4be8-a50c-fb807a52380f", "label": "a", "points": [[5, 1.9], [5, 676.7], [675.5, 676.7], [675.5, 1.9]], "color": "yellow"}, {"id": "cc7b6aa5-f5a1-4565-a8b3-36baf5f0c23e", "label": "b", "points": [[688.5, 10.6], [688.5, 683.2], [1367.7, 683.2], [1367.7, 10.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "MRI", "start": 9, "end": 12, "id": 2}, {"text": "perfusion", "start": 13, "end": 22, "id": 3}, {"text": "scan", "start": 23, "end": 27, "id": 4}, {"text": "at", "start": 28, "end": 30, "id": 5}, {"text": "baseline", "start": 31, "end": 39, "id": 6}, {"text": "and", "start": 40, "end": 43, "id": 7}, {"text": "follow", "start": 44, "end": 50, "id": 8}, {"text": "-", "start": 50, "end": 51, "id": 9}, {"text": "up", "start": 51, "end": 53, "id": 10}, {"text": "in", "start": 54, "end": 56, "id": 11}, {"text": "one", "start": 57, "end": 60, "id": 12}, {"text": "patient", "start": 61, "end": 68, "id": 13}, {"text": "treated", "start": 69, "end": 76, "id": 14}, {"text": "with", "start": 77, "end": 81, "id": 15}, {"text": "VEGF", "start": 82, "end": 86, "id": 16}, {"text": "-", "start": 86, "end": 87, "id": 17}, {"text": "A", "start": 87, "end": 88, "id": 18}, {"text": "165", "start": 89, "end": 92, "id": 19}, {"text": "gene", "start": 93, "end": 97, "id": 20}, {"text": "transfer", "start": 98, "end": 106, "id": 21}, {"text": "followed", "start": 107, "end": 115, "id": 22}, {"text": "by", "start": 116, "end": 118, "id": 23}, {"text": "G", "start": 119, "end": 120, "id": 24}, {"text": "-", "start": 120, "end": 121, "id": 25}, {"text": "CSF", "start": 121, "end": 124, "id": 26}, {"text": ".", "start": 124, "end": 125, "id": 27}, {"text": "The", "start": 126, "end": 129, "id": 28}, {"text": "recordings", "start": 130, "end": 140, "id": 29}, {"text": "were", "start": 141, "end": 145, "id": 30}, {"text": "performed", "start": 146, "end": 155, "id": 31}, {"text": "20", "start": 156, "end": 158, "id": 32}, {"text": "s", "start": 159, "end": 160, "id": 33}, {"text": "after", "start": 161, "end": 166, "id": 34}, {"text": "contrast", "start": 167, "end": 175, "id": 35}, {"text": "infusion", "start": 176, "end": 184, "id": 36}, {"text": ",", "start": 184, "end": 185, "id": 37}, {"text": "demonstrating", "start": 186, "end": 199, "id": 38}, {"text": "poor", "start": 200, "end": 204, "id": 39}, {"text": "perfusion", "start": 205, "end": 214, "id": 40}, {"text": "with", "start": 215, "end": 219, "id": 41}, {"text": "no", "start": 220, "end": 222, "id": 42}, {"text": "contrast", "start": 223, "end": 231, "id": 43}, {"text": "enhancement", "start": 232, "end": 243, "id": 44}, {"text": "in", "start": 244, "end": 246, "id": 45}, {"text": "the", "start": 247, "end": 250, "id": 46}, {"text": "lateral", "start": 251, "end": 258, "id": 47}, {"text": "wall", "start": 259, "end": 263, "id": 48}, {"text": "(", "start": 264, "end": 265, "id": 49}, {"text": "black", "start": 265, "end": 270, "id": 50}, {"text": "arrows", "start": 271, "end": 277, "id": 51}, {"text": ")", "start": 277, "end": 278, "id": 52}, {"text": ",", "start": 278, "end": 279, "id": 53}, {"text": "moderate", "start": 280, "end": 288, "id": 54}, {"text": "perfusion", "start": 289, "end": 298, "id": 55}, {"text": "with", "start": 299, "end": 303, "id": 56}, {"text": "attenuated", "start": 304, "end": 314, "id": 57}, {"text": "enhancement", "start": 315, "end": 326, "id": 58}, {"text": "(", "start": 327, "end": 328, "id": 59}, {"text": "white", "start": 328, "end": 333, "id": 60}, {"text": "arrows", "start": 334, "end": 340, "id": 61}, {"text": ")", "start": 340, "end": 341, "id": 62}, {"text": "in", "start": 342, "end": 344, "id": 63}, {"text": "the", "start": 345, "end": 348, "id": 64}, {"text": "inferior", "start": 349, "end": 357, "id": 65}, {"text": "wall", "start": 358, "end": 362, "id": 66}, {"text": ",", "start": 362, "end": 363, "id": 67}, {"text": "and", "start": 364, "end": 367, "id": 68}, {"text": "normal", "start": 368, "end": 374, "id": 69}, {"text": "perfusion", "start": 375, "end": 384, "id": 70}, {"text": "in", "start": 385, "end": 387, "id": 71}, {"text": "the", "start": 388, "end": 391, "id": 72}, {"text": "anterior", "start": 392, "end": 400, "id": 73}, {"text": "wall", "start": 401, "end": 405, "id": 74}, {"text": "(", "start": 406, "end": 407, "id": 75}, {"text": "transparent", "start": 407, "end": 418, "id": 76}, {"text": "arrows", "start": 419, "end": 425, "id": 77}, {"text": ")", "start": 425, "end": 426, "id": 78}, {"text": ".", "start": 426, "end": 427, "id": 79}]}
{"pdf_hash": "b2a2a176e2d5686352ce5d70760dd9085036f7af", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. Cell morphology from one Ct and two B-ALL BM samples. Microscopic evaluation of three BM samples, as examples: (A) Ct, (B) B-ALL (Pre-pre B), (C) B-ALL (Pre-B) (scale bar: 30 lm) (Olympus CK2, magnification 100\u00b7).", "width": 1322, "height": 522, "subcaptions": {"a": [26, 27, 28, 29], "b": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "c": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "9f592c9b-d07b-4660-89f4-823ab2155c84", "label": "a", "points": [[45, 5.9], [45, 488.3], [458.5, 488.3], [458.5, 5.9]], "color": "yellow"}, {"id": "02075eee-6c16-4ca6-a128-e62037c28560", "label": "b", "points": [[475.2, 3.8], [475.2, 488.3], [861.5, 488.3], [861.5, 3.8]], "color": "cyan"}, {"id": "8fc6f17f-8c6a-420f-ab2a-fd1680169f84", "label": "c", "points": [[874, 8], [874, 492.5], [1293.8, 492.5], [1293.8, 8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Cell", "start": 10, "end": 14, "id": 3}, {"text": "morphology", "start": 15, "end": 25, "id": 4}, {"text": "from", "start": 26, "end": 30, "id": 5}, {"text": "one", "start": 31, "end": 34, "id": 6}, {"text": "Ct", "start": 35, "end": 37, "id": 7}, {"text": "and", "start": 38, "end": 41, "id": 8}, {"text": "two", "start": 42, "end": 45, "id": 9}, {"text": "B", "start": 46, "end": 47, "id": 10}, {"text": "-", "start": 47, "end": 48, "id": 11}, {"text": "ALL", "start": 48, "end": 51, "id": 12}, {"text": "BM", "start": 52, "end": 54, "id": 13}, {"text": "samples", "start": 55, "end": 62, "id": 14}, {"text": ".", "start": 62, "end": 63, "id": 15}, {"text": "Microscopic", "start": 64, "end": 75, "id": 16}, {"text": "evaluation", "start": 76, "end": 86, "id": 17}, {"text": "of", "start": 87, "end": 89, "id": 18}, {"text": "three", "start": 90, "end": 95, "id": 19}, {"text": "BM", "start": 96, "end": 98, "id": 20}, {"text": "samples", "start": 99, "end": 106, "id": 21}, {"text": ",", "start": 106, "end": 107, "id": 22}, {"text": "as", "start": 108, "end": 110, "id": 23}, {"text": "examples", "start": 111, "end": 119, "id": 24}, {"text": ":", "start": 119, "end": 120, "id": 25}, {"text": "(", "start": 121, "end": 122, "id": 26}, {"text": "A", "start": 122, "end": 123, "id": 27}, {"text": ")", "start": 123, "end": 124, "id": 28}, {"text": "Ct", "start": 125, "end": 127, "id": 29}, {"text": ",", "start": 127, "end": 128, "id": 30}, {"text": "(", "start": 129, "end": 130, "id": 31}, {"text": "B", "start": 130, "end": 131, "id": 32}, {"text": ")", "start": 131, "end": 132, "id": 33}, {"text": "B", "start": 133, "end": 134, "id": 34}, {"text": "-", "start": 134, "end": 135, "id": 35}, {"text": "ALL", "start": 135, "end": 138, "id": 36}, {"text": "(", "start": 139, "end": 140, "id": 37}, {"text": "Pre", "start": 140, "end": 143, "id": 38}, {"text": "-", "start": 143, "end": 144, "id": 39}, {"text": "pre", "start": 144, "end": 147, "id": 40}, {"text": "B", "start": 148, "end": 149, "id": 41}, {"text": ")", "start": 149, "end": 150, "id": 42}, {"text": ",", "start": 150, "end": 151, "id": 43}, {"text": "(", "start": 152, "end": 153, "id": 44}, {"text": "C", "start": 153, "end": 154, "id": 45}, {"text": ")", "start": 154, "end": 155, "id": 46}, {"text": "B", "start": 156, "end": 157, "id": 47}, {"text": "-", "start": 157, "end": 158, "id": 48}, {"text": "ALL", "start": 158, "end": 161, "id": 49}, {"text": "(", "start": 162, "end": 163, "id": 50}, {"text": "Pre", "start": 163, "end": 166, "id": 51}, {"text": "-", "start": 166, "end": 167, "id": 52}, {"text": "B", "start": 167, "end": 168, "id": 53}, {"text": ")", "start": 168, "end": 169, "id": 54}, {"text": "(", "start": 170, "end": 171, "id": 55}, {"text": "scale", "start": 171, "end": 176, "id": 56}, {"text": "bar", "start": 177, "end": 180, "id": 57}, {"text": ":", "start": 180, "end": 181, "id": 58}, {"text": "30", "start": 182, "end": 184, "id": 59}, {"text": "lm", "start": 185, "end": 187, "id": 60}, {"text": ")", "start": 187, "end": 188, "id": 61}, {"text": "(", "start": 189, "end": 190, "id": 62}, {"text": "Olympus", "start": 190, "end": 197, "id": 63}, {"text": "CK2", "start": 198, "end": 201, "id": 64}, {"text": ",", "start": 201, "end": 202, "id": 65}, {"text": "magnification", "start": 203, "end": 216, "id": 66}, {"text": "100", "start": 217, "end": 220, "id": 67}, {"text": "\u00b7", "start": 220, "end": 221, "id": 68}, {"text": ")", "start": 221, "end": 222, "id": 69}, {"text": ".", "start": 222, "end": 223, "id": 70}]}
{"pdf_hash": "a086c3482b729853f65d0c6661c65cbb1684a1cf", "fig_key": "Figure8", "fig_uri": "8-Figure8-1.png", "text": "FIG. 8. Representative injections of Feridex-labeled MSCs into the myocardium. a: Still frames depicting the infarcted myocardium highlighted by MDE imaging and indicated by arrows. b: The distal tip of the catheter is apposed against the infarct in the mid-apical septum under real-time MR guidance. c: A 30-mM Gd-DTPA injection is carried out and visualized as a hyperintense lesion. d: Feridex-labeled MSCs (7 106) are injected at the same location. e: The catheter was then repositioned below the previous injection site, and 30 mM Gd-DTPA were injected. f: Feridex-labeled MSCs (3 106 labeled, and 4 106 unlabeled) are injected at the same location, and both injections are visualized (the Gd-DTPA injection is bright, and the hypointense Feridex-labeled MSC injection is dark). The lower concentration of labeled MSCs can be appreciated as a less hypointense lesion in the more apical injection. All of the images were acquired with the use of a real-time SSFP sequence (TR 3.4 ms, TE 1.2 ms, FA 45\u00b0 (90\u00b0 for c and e), BW 125, image matrix 128 128, NEX 0.5) and the i-Drive interface to guide the procedure.", "width": 1026, "height": 568, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "c": [58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75], "d": [76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92], "e": [93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114], "f": [115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163]}, "subfigures": [{"id": 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{"pdf_hash": "a4fb0a6119bb8e06ba623513d4b2ef1a5cb690d9", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. (A) T1-weighted gadolinium-enhanced magnetic resonance imaging reveals a focal-enhancing mass in hepatic segment 7 (arrow). This mass demonstrated venous phase-contrast washout, meeting the guidelines for HCC. After discussion at multidiscipline tumor board, this nonoperative candidate underwent cTACE. (B) A noncontrast computed tomography scan performed immediately after cTACE revealed focal uptake of lipiodol within the targeted tumor (double arrows). 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{"pdf_hash": "c0bf5bb7146d8ff13e0bcc7fa8f9f7deeee5238d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (a) Injury of the orbit from penetration by a pencil. Clinical features include proptosis, chemosis, and loss of vision due to raised intraorbital pressure. (b) CT scan identifies gas within the orbit, which together with the soft tissue swelling, accounts for the rise in orbital pressure. b a", "width": 710, "height": 290, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "b34f59e5-6802-4435-8dd3-a49a15128a08", "label": "a", "points": [[37.6, 31.2], [37.6, 265.6], [380.8, 265.6], [380.8, 31.2]], "color": "yellow"}, {"id": "733dc418-f0be-4398-a657-b6bcf39160cf", "label": "b", "points": [[390.9, 34.6], [390.9, 263.4], [706.1, 263.4], [706.1, 34.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Injury", "start": 14, "end": 20, "id": 6}, {"text": "of", "start": 21, "end": 23, "id": 7}, {"text": "the", "start": 24, "end": 27, "id": 8}, {"text": "orbit", "start": 28, "end": 33, "id": 9}, {"text": "from", "start": 34, "end": 38, "id": 10}, {"text": "penetration", "start": 39, "end": 50, "id": 11}, {"text": "by", "start": 51, "end": 53, "id": 12}, {"text": "a", "start": 54, "end": 55, "id": 13}, {"text": "pencil", "start": 56, "end": 62, "id": 14}, {"text": ".", "start": 62, "end": 63, "id": 15}, {"text": "Clinical", "start": 64, "end": 72, "id": 16}, {"text": "features", "start": 73, "end": 81, "id": 17}, {"text": "include", "start": 82, "end": 89, "id": 18}, {"text": "proptosis", "start": 90, "end": 99, "id": 19}, {"text": ",", "start": 99, "end": 100, "id": 20}, {"text": "chemosis", "start": 101, "end": 109, "id": 21}, {"text": ",", "start": 109, "end": 110, "id": 22}, {"text": "and", "start": 111, "end": 114, "id": 23}, {"text": "loss", "start": 115, "end": 119, "id": 24}, {"text": "of", "start": 120, "end": 122, "id": 25}, {"text": "vision", "start": 123, "end": 129, "id": 26}, {"text": "due", "start": 130, "end": 133, "id": 27}, {"text": "to", "start": 134, "end": 136, "id": 28}, {"text": "raised", "start": 137, "end": 143, "id": 29}, {"text": "intraorbital", "start": 144, "end": 156, "id": 30}, {"text": "pressure", "start": 157, "end": 165, "id": 31}, {"text": ".", "start": 165, "end": 166, "id": 32}, {"text": "(", "start": 167, "end": 168, "id": 33}, {"text": "b", "start": 168, "end": 169, "id": 34}, {"text": ")", "start": 169, "end": 170, "id": 35}, {"text": "CT", "start": 171, "end": 173, "id": 36}, {"text": "scan", "start": 174, "end": 178, "id": 37}, {"text": "identifies", "start": 179, "end": 189, "id": 38}, {"text": "gas", "start": 190, "end": 193, "id": 39}, {"text": "within", "start": 194, "end": 200, "id": 40}, {"text": "the", "start": 201, "end": 204, "id": 41}, {"text": "orbit", "start": 205, "end": 210, "id": 42}, {"text": ",", "start": 210, "end": 211, "id": 43}, {"text": "which", "start": 212, "end": 217, "id": 44}, {"text": "together", "start": 218, "end": 226, "id": 45}, {"text": "with", "start": 227, "end": 231, "id": 46}, {"text": "the", "start": 232, "end": 235, "id": 47}, {"text": "soft", "start": 236, "end": 240, "id": 48}, {"text": "tissue", "start": 241, "end": 247, "id": 49}, {"text": "swelling", "start": 248, "end": 256, "id": 50}, {"text": ",", "start": 256, "end": 257, "id": 51}, {"text": "accounts", "start": 258, "end": 266, "id": 52}, {"text": "for", "start": 267, "end": 270, "id": 53}, {"text": "the", "start": 271, "end": 274, "id": 54}, {"text": "rise", "start": 275, "end": 279, "id": 55}, {"text": "in", "start": 280, "end": 282, "id": 56}, {"text": "orbital", "start": 283, "end": 290, "id": 57}, {"text": "pressure", "start": 291, "end": 299, "id": 58}, {"text": ".", "start": 299, "end": 300, "id": 59}, {"text": "b", "start": 301, "end": 302, "id": 60}, {"text": "a", "start": 303, "end": 304, "id": 61}]}
{"pdf_hash": "9d925a59dbb87c4259a36dbc4dc549581d62c391", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3 Laser disruptions of a cerebral capillary (1) and a branch vessel (2) on mouse cortex. Upper panel: maximum intensity projection (MIP) images of microvasculature imaging (optical coherence angiography) at baseline (a), after laser disruption of a f9 mm capillary (b) and of a f35.8 mm arteriole (c). Red/blue arrows: flow directions of arterioles/venules, dots: vessel junctures. Lower panel: MIP images of cerebral blood flow (CBF; microvascular imaging by optical Doppler tomography) at baseline (d) and after laser disruptions (e, f). Angiography detects no difference except reduced vasculature in the immediate areas (dashed green circles in panels b and c) around laser disruption (green dots); whereas quantitative CBF reveals vastly expanded vasodilatation almost over the entire field after laser disruption of a capillary (dashed outer green circle in panel e) and the quenching of local CBF networks over a much larger area (dashed green circle in panel e). Quantitative comparisons among 20 capillaries indicate that CBF increased significantly from 0.105\u00b10.049 mm s \u00c01 at baseline to 0.211\u00b10.048 mm s \u00c01 at 30 min after laser disruption (g and h; P < 0.001). Image size: 1 \u00c2 1.2 \u00c2 1 mm 3 . 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{"pdf_hash": "a09730567ed6339e854fa78fe5f46323533ac48b", "fig_key": "Figure8", "fig_uri": "8-Figure8-1.png", "text": "Figure 8. SEM images of PDMS/ODA-coated PET fabric (a) after 1 st plasma treatment, (b) after 1 st automatically healed at room temperature for 12 h, (c) after 8 times etching-healing cycles at room temperature, (d) after 7 times etching-heating cycles.", "width": 1092, "height": 820, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "c": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "d": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "c2378ede-b9e0-489c-bb3a-71471d7d39c9", "label": "a", "points": [[3.5, 5.2], [3.5, 388.2], [546.9, 388.2], [546.9, 5.2]], "color": "yellow"}, {"id": "68caa1c0-68cf-4f16-b73b-25aa995a25ad", "label": "b", "points": [[553.8, 388.2], [553.8, 6.9], [1085.1, 6.9], [1085.1, 388.2]], "color": "cyan"}, {"id": "bd234006-f47b-4a3b-a821-277dead252b9", "label": "c", "points": [[548.6, 412.3], [548.6, 791.8], [6.9, 791.8], [6.9, 412.3]], "color": "magenta"}, {"id": "2ae7204b-4618-491a-9304-fe5a424c779e", "label": "d", "points": [[557.2, 417.5], [557.2, 788.4], [1085.1, 788.4], [1085.1, 417.5]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "8", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "SEM", "start": 10, "end": 13, "id": 3}, {"text": "images", "start": 14, "end": 20, "id": 4}, {"text": "of", "start": 21, "end": 23, "id": 5}, {"text": "PDMS", "start": 24, "end": 28, "id": 6}, {"text": "/", "start": 28, "end": 29, "id": 7}, {"text": "ODA", "start": 29, "end": 32, "id": 8}, {"text": "-", "start": 32, "end": 33, "id": 9}, {"text": "coated", "start": 33, "end": 39, "id": 10}, {"text": "PET", "start": 40, "end": 43, "id": 11}, {"text": "fabric", "start": 44, "end": 50, "id": 12}, {"text": "(", "start": 51, "end": 52, "id": 13}, {"text": "a", "start": 52, "end": 53, "id": 14}, {"text": ")", "start": 53, "end": 54, "id": 15}, {"text": "after", "start": 55, "end": 60, "id": 16}, {"text": "1", "start": 61, "end": 62, "id": 17}, {"text": "st", "start": 63, "end": 65, "id": 18}, {"text": "plasma", "start": 66, "end": 72, "id": 19}, {"text": "treatment", "start": 73, "end": 82, "id": 20}, {"text": ",", "start": 82, "end": 83, "id": 21}, {"text": "(", "start": 84, "end": 85, "id": 22}, {"text": "b", "start": 85, "end": 86, "id": 23}, {"text": ")", "start": 86, "end": 87, "id": 24}, {"text": "after", "start": 88, "end": 93, "id": 25}, {"text": "1", "start": 94, "end": 95, "id": 26}, {"text": "st", "start": 96, "end": 98, "id": 27}, {"text": "automatically", "start": 99, "end": 112, "id": 28}, {"text": "healed", "start": 113, "end": 119, "id": 29}, {"text": "at", "start": 120, "end": 122, "id": 30}, {"text": "room", "start": 123, "end": 127, "id": 31}, {"text": "temperature", "start": 128, "end": 139, "id": 32}, {"text": "for", "start": 140, "end": 143, "id": 33}, {"text": "12", "start": 144, "end": 146, "id": 34}, {"text": "h", "start": 147, "end": 148, "id": 35}, {"text": ",", "start": 148, "end": 149, "id": 36}, {"text": "(", "start": 150, "end": 151, "id": 37}, {"text": "c", "start": 151, "end": 152, "id": 38}, {"text": ")", "start": 152, "end": 153, "id": 39}, {"text": "after", "start": 154, "end": 159, "id": 40}, {"text": "8", "start": 160, "end": 161, "id": 41}, {"text": "times", "start": 162, "end": 167, "id": 42}, {"text": "etching", "start": 168, "end": 175, "id": 43}, {"text": "-", "start": 175, "end": 176, "id": 44}, {"text": "healing", "start": 176, "end": 183, "id": 45}, {"text": "cycles", "start": 184, "end": 190, "id": 46}, {"text": "at", "start": 191, "end": 193, "id": 47}, {"text": "room", "start": 194, "end": 198, "id": 48}, {"text": "temperature", "start": 199, "end": 210, "id": 49}, {"text": ",", "start": 210, "end": 211, "id": 50}, {"text": "(", "start": 212, "end": 213, "id": 51}, {"text": "d", "start": 213, "end": 214, "id": 52}, {"text": ")", "start": 214, "end": 215, "id": 53}, {"text": "after", "start": 216, "end": 221, "id": 54}, {"text": "7", "start": 222, "end": 223, "id": 55}, {"text": "times", "start": 224, "end": 229, "id": 56}, {"text": "etching", "start": 230, "end": 237, "id": 57}, {"text": "-", "start": 237, "end": 238, "id": 58}, {"text": "heating", "start": 238, "end": 245, "id": 59}, {"text": "cycles", "start": 246, "end": 252, "id": 60}, {"text": ".", "start": 252, "end": 253, "id": 61}]}
{"pdf_hash": "4dcdb1cf9570de627a5edac95f606bb630f6634f", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIGURE 1 Imaging and histological correlation in lung adenocarcinoma classification. a) Computed tomography (CT) scan demonstrating a ground-glass nodule that on resection represents adenocarcinoma in situ. b) The preserved alveolar architecture is seen at low magnification in this adenocarcinoma in situ. Scale bar=3 mm. c) CT scan demonstrating a solid area surrounded by a rim of ground-glass attenutation. d) On resection, this was an acinar predominant adenocarcinoma with gland formation seen on the histology image.", "width": 1076, "height": 846, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "c": [54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71], "d": [72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91]}, "subfigures": [{"id": "7e0b47ea-9e06-4ca5-b7da-5e975ee19781", "label": "a", "points": [[529.5, 370.3], [529.5, -0.3], [0.9, -0.3], [0.9, 370.3]], "color": "yellow"}, {"id": "18deda39-2d33-4fe0-8c9e-53cde7126f93", "label": "b", "points": [[546.5, 1.4], [546.5, 377.1], [1066.7, 377.1], [1066.7, 1.4]], "color": "cyan"}, {"id": "c81b5630-da76-4d15-910c-462068885cdb", "label": "c", "points": [[9.4, 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{"pdf_hash": "1e581cc067aebaf738a786d7b02e79efe647b1cc", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3. 66-year-old male with dedifferentiated liposarcoma of the right breast. Targeted right breast ultrasound was performed in the areas of the palpable and the mammographic abnormalities. A. Transverse and sagittal images of the right breast, 11-12 o\u2019clock region, show a 9.2-cm isoechoic mass with a 4-cm cystic component.\u00a0B. Transverse and sagittal images of the right axilla show a 3.9-cm hypoechoic mass with irregular margins, suspicious for malignancy.", "width": 496, "height": 808, "subcaptions": {"a": [60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81]}, "subfigures": [{"id": "8a7a5185-2128-46dd-877f-76a57563a130", "label": "a", "points": [[5.8, 0.9], [5.8, 385.9], [230.8, 385.9], [230.8, 0.9]], "color": "yellow"}, {"id": "172d2ec0-af84-43da-b318-f7ef7347d717", "label": "a", "points": [[242.8, 1.9], [242.8, 388.9], [485.8, 388.9], [485.8, 1.9]], "color": "cyan"}, {"id": "f7e18ff5-ad0c-4e77-9346-e1bbddefe589", "label": "b", "points": [[4.8, 400.9], [4.8, 786.9], [236.8, 786.9], [236.8, 400.9]], "color": "magenta"}, {"id": "3539112e-387e-4f9b-930c-455438781753", "label": "b", "points": [[241.8, 400.9], [241.8, 792.9], [493.8, 792.9], [493.8, 400.9]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, 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{"pdf_hash": "67da5e46f5c730f5dd7dc0d0cbfb32dabc8464dc", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. Different emphases in the investigation of neural mechanisms for associative prediction vs. perceptual expertise. A: Medial view of the typical contextual association network (e.g., Bar and Aminoff, 2003) and its overlap with the default network (e.g., Raichle et al., 2001). The context network activations are obtained from the contrast between strongly contextually associative objects (e.g., a tennis racket) and weakly contextually associative objects (e.g., a jacket). The default network regions are those that are more active during fixation rest than during task performance. MPC, medial parietal cortex. MTL, middle temporal lobe. MPFC, medial prefrontal cortex. B: An axial oblique slice through the right \u2018fusiform face area\u2019 (FFA, marked with a red circle), one of the local regions emphasized in several perceptual expertise studies (for subordinate-level expertise, e.g., Gauthier et al., 1999, 2000a,b; Wong et al., 2009b), for a car expert and a bird expert. The FFA was first defined by more robust activations for faces than objects. In Gauthier et al. (2000a), this area was found to be more activated for car experts when viewing cars compared to other objects, and for bird experts when viewing birds compared to other objects. Copyrights \u00a9 by Elsevier Ltd. and Nature America Inc. respectively. 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{"pdf_hash": "73fadadc45ae06d9a4088a33546cce17603e6a19", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4. CT. a. The maximum diameter of the tumor was 45 mm in 1997. b: In 2001, the maximum diameter was de creased to 31 mm with cystic change in the periphery of the tumor (arrow). c: The maximum diameter had become 15 mm by 2007.", "width": 474, "height": 1296, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "c": [45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "6407be4c-d036-44e6-9e94-57c28ce8dfdb", "label": "a", "points": [[21, 2.8], [21, 417.8], [474, 417.8], [474, 2.8]], "color": "yellow"}, {"id": "d1a303e5-23ec-4507-9ca1-0c9951482f80", "label": "b", "points": [[22, 424.3], [22, 843.3], [473, 843.3], [473, 424.3]], "color": "cyan"}, {"id": "1ac254c8-1e6b-4357-ae11-ed6044988577", "label": "c", "points": [[20, 849.3], [20, 1265.3], [472, 1265.3], [472, 849.3]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": ".", "start": 12, "end": 13, "id": 4}, {"text": "a.", "start": 14, "end": 16, "id": 5}, {"text": "The", "start": 17, "end": 20, "id": 6}, {"text": "maximum", "start": 21, "end": 28, "id": 7}, {"text": "diameter", "start": 29, "end": 37, "id": 8}, {"text": "of", "start": 38, "end": 40, "id": 9}, {"text": "the", "start": 41, "end": 44, "id": 10}, {"text": "tumor", "start": 45, "end": 50, "id": 11}, {"text": "was", "start": 51, "end": 54, "id": 12}, {"text": "45", "start": 55, "end": 57, "id": 13}, {"text": "mm", "start": 58, "end": 60, "id": 14}, {"text": "in", "start": 61, "end": 63, "id": 15}, {"text": "1997", "start": 64, "end": 68, "id": 16}, {"text": ".", "start": 68, "end": 69, "id": 17}, {"text": "b", "start": 70, "end": 71, "id": 18}, {"text": ":", "start": 71, "end": 72, "id": 19}, {"text": "In", "start": 73, "end": 75, "id": 20}, {"text": "2001", "start": 76, "end": 80, "id": 21}, {"text": ",", "start": 80, "end": 81, "id": 22}, {"text": "the", "start": 82, "end": 85, "id": 23}, {"text": "maximum", "start": 86, "end": 93, "id": 24}, {"text": "diameter", "start": 94, "end": 102, "id": 25}, {"text": "was", "start": 103, "end": 106, "id": 26}, {"text": "de", "start": 107, "end": 109, "id": 27}, {"text": "creased", "start": 110, "end": 117, "id": 28}, {"text": "to", "start": 118, "end": 120, "id": 29}, {"text": "31", "start": 121, "end": 123, "id": 30}, {"text": "mm", "start": 124, "end": 126, "id": 31}, {"text": "with", "start": 127, "end": 131, "id": 32}, {"text": "cystic", "start": 132, "end": 138, "id": 33}, {"text": "change", "start": 139, "end": 145, "id": 34}, {"text": "in", "start": 146, "end": 148, "id": 35}, {"text": "the", "start": 149, "end": 152, "id": 36}, {"text": "periphery", "start": 153, "end": 162, "id": 37}, {"text": "of", "start": 163, "end": 165, "id": 38}, {"text": "the", "start": 166, "end": 169, "id": 39}, {"text": "tumor", "start": 170, "end": 175, "id": 40}, {"text": "(", "start": 176, "end": 177, "id": 41}, {"text": "arrow", "start": 177, "end": 182, "id": 42}, {"text": ")", "start": 182, "end": 183, "id": 43}, {"text": ".", "start": 183, "end": 184, "id": 44}, {"text": "c", "start": 185, "end": 186, "id": 45}, {"text": ":", "start": 186, "end": 187, "id": 46}, {"text": "The", "start": 188, "end": 191, "id": 47}, {"text": "maximum", "start": 192, "end": 199, "id": 48}, {"text": "diameter", "start": 200, "end": 208, "id": 49}, {"text": "had", "start": 209, "end": 212, "id": 50}, {"text": "become", "start": 213, "end": 219, "id": 51}, {"text": "15", "start": 220, "end": 222, "id": 52}, {"text": "mm", "start": 223, "end": 225, "id": 53}, {"text": "by", "start": 226, "end": 228, "id": 54}, {"text": "2007", "start": 229, "end": 233, "id": 55}, {"text": ".", "start": 233, "end": 234, "id": 56}]}
{"pdf_hash": "8e3f19968bdd14c5b1e97f2ca89a8736462323d1", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. a, b. A 77-year-old female patient with multiple metastases from lung cancer. Sagittal T2 Dixon water-only image (a) provides uniform fat suppression and shows clear extent of metastases at L3, L5, S1, S2, and S3. SPAIR image (b) fails to show the full extent of metastases due to incomplete fat suppression at coccyx region.", "width": 968, "height": 818, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "b": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72]}, "subfigures": [{"id": "fcff5ce0-1579-4d92-b24e-f3bdffd1856b", "label": "a", "points": [[6.9, 1.3], [6.9, 784.2], [442.7, 784.2], [442.7, 1.3]], "color": "yellow"}, {"id": "f4c7c934-f66d-464c-bf01-c128fa5dbaf8", "label": "b", "points": [[488.6, 2.8], [488.6, 784.2], [930.5, 784.2], [930.5, 2.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "b.", "start": 13, "end": 15, "id": 5}, {"text": "A", "start": 16, "end": 17, "id": 6}, {"text": "77-year", "start": 18, "end": 25, "id": 7}, {"text": "-", "start": 25, "end": 26, "id": 8}, {"text": "old", "start": 26, "end": 29, "id": 9}, {"text": "female", "start": 30, "end": 36, "id": 10}, {"text": "patient", "start": 37, "end": 44, "id": 11}, {"text": "with", "start": 45, "end": 49, "id": 12}, {"text": "multiple", "start": 50, "end": 58, "id": 13}, {"text": "metastases", "start": 59, "end": 69, "id": 14}, {"text": "from", "start": 70, "end": 74, "id": 15}, {"text": "lung", "start": 75, "end": 79, "id": 16}, {"text": "cancer", "start": 80, "end": 86, "id": 17}, {"text": ".", "start": 86, "end": 87, "id": 18}, {"text": "Sagittal", "start": 88, "end": 96, "id": 19}, {"text": "T2", "start": 97, "end": 99, "id": 20}, {"text": "Dixon", "start": 100, "end": 105, "id": 21}, {"text": "water", "start": 106, "end": 111, "id": 22}, {"text": "-", "start": 111, "end": 112, "id": 23}, {"text": "only", "start": 112, "end": 116, "id": 24}, {"text": "image", "start": 117, "end": 122, "id": 25}, {"text": "(", "start": 123, "end": 124, "id": 26}, {"text": "a", "start": 124, "end": 125, "id": 27}, {"text": ")", "start": 125, "end": 126, "id": 28}, {"text": "provides", "start": 127, "end": 135, "id": 29}, {"text": "uniform", "start": 136, "end": 143, "id": 30}, {"text": "fat", "start": 144, "end": 147, "id": 31}, {"text": "suppression", "start": 148, "end": 159, "id": 32}, {"text": "and", "start": 160, "end": 163, "id": 33}, {"text": "shows", "start": 164, "end": 169, "id": 34}, {"text": "clear", "start": 170, "end": 175, "id": 35}, {"text": "extent", "start": 176, "end": 182, "id": 36}, {"text": "of", "start": 183, "end": 185, "id": 37}, {"text": "metastases", "start": 186, "end": 196, "id": 38}, {"text": "at", "start": 197, "end": 199, "id": 39}, {"text": "L3", "start": 200, "end": 202, "id": 40}, {"text": ",", "start": 202, "end": 203, "id": 41}, {"text": "L5", "start": 204, "end": 206, "id": 42}, {"text": ",", "start": 206, "end": 207, "id": 43}, {"text": "S1", "start": 208, "end": 210, "id": 44}, {"text": ",", "start": 210, "end": 211, "id": 45}, {"text": "S2", "start": 212, "end": 214, "id": 46}, {"text": ",", "start": 214, "end": 215, "id": 47}, {"text": "and", "start": 216, "end": 219, "id": 48}, {"text": "S3", "start": 220, "end": 222, "id": 49}, {"text": ".", "start": 222, "end": 223, "id": 50}, {"text": "SPAIR", "start": 224, "end": 229, "id": 51}, {"text": "image", "start": 230, "end": 235, "id": 52}, {"text": "(", "start": 236, "end": 237, "id": 53}, {"text": "b", "start": 237, "end": 238, "id": 54}, {"text": ")", "start": 238, "end": 239, "id": 55}, {"text": "fails", "start": 240, "end": 245, "id": 56}, {"text": "to", "start": 246, "end": 248, "id": 57}, {"text": "show", "start": 249, "end": 253, "id": 58}, {"text": "the", "start": 254, "end": 257, "id": 59}, {"text": "full", "start": 258, "end": 262, "id": 60}, {"text": "extent", "start": 263, "end": 269, "id": 61}, {"text": "of", "start": 270, "end": 272, "id": 62}, {"text": "metastases", "start": 273, "end": 283, "id": 63}, {"text": "due", "start": 284, "end": 287, "id": 64}, {"text": "to", "start": 288, "end": 290, "id": 65}, {"text": "incomplete", "start": 291, "end": 301, "id": 66}, {"text": "fat", "start": 302, "end": 305, "id": 67}, {"text": "suppression", "start": 306, "end": 317, "id": 68}, {"text": "at", "start": 318, "end": 320, "id": 69}, {"text": "coccyx", "start": 321, "end": 327, "id": 70}, {"text": "region", "start": 328, "end": 334, "id": 71}, {"text": ".", "start": 334, "end": 335, "id": 72}]}
{"pdf_hash": "a872f5c01c41d91a74d0052dd13f35bc21ccdd73", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "FIG. 2. Adult rat thymocytes. Transferase was stained as in Fig. 1. (X775.) (A) Small thymocytes displaying combined cytoplasmic (peripheral \"halo\") and nuclear (central stippling) patterns of fluorescence. (B and C) Large thymocytes with nuclear pattern of fluorescence similar to that in Fig. 1 B and C. Note absence of cytoplasmic and nucleolar fluorescence. medium-sized, lymphocyte-like bone marrow cells showed a coarsely clumped pattern of intranuclear fluorescence that resembled the aggregated pattern of heterochromatin seen in Wright's stained preparations. Some large, blast-like bone marrow cells exhibited a more diffuse, finely granular pattern of intranuclear fluorescence that resembled the dispersed chromatin pattern seen in these cells. Thy-1.i Antigen on Transferase-Positive Bone Marrow Cells. Adult rat bone marrow cells were tested for the simultaneous presence of Thy-1.1 and transferase antigens by dual immunofluorescence. Anti-Thy-i.i staining (rhodamine-positive) was restricted to the cell surface; anti-transferase staining (fluorescein-positive) was restricted to the cell nucleus. Approximately 30% of nucleated bone marrow cells were found to be Thy-1.1 positive, as reported elsewhere (18). Of these, approximately 10% were transferase-positive (i.e., showed dual fluorescence). Conversely, essentially all transferase-positive bone marrow cells were Thy-i. I positive. Intranuclear Distribution of Terminal Transferase in Thymocytes. As we and others have reported (2, 14), terminal transferase appears to occupy a predominantly cytoplasmic position in cortical thymocytes from adult rats. The use of a Cytospin centrifuge to prepare cell smears and the use of affinity-column-purified anti-transferase for immunofluorescence permitted more precise resolution of the intracellular distribution of this enzyme in the present experiments. In the flattened preparation from the cytocentrifuge, many small thymocytes had detectable nuclear fluorescence as well as cytoplasmic fluorescence (Fig. 2A). 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{"pdf_hash": "0ae0afb44ca489c7dbf126da164a4d15f43e3950", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1: Abdominal MRI T2 FFE (fast field echo) sequences show hypointense liver, spleen, pancreas and bone signal due to abnormal iron deposition. (A, B) patients with intense transfusion regimen history; (C) patient with only 5 transfusion before MRI quantification of iron concentration; (D) patient treated with deferasirox: minor liver hyperintensity compared to spleen, pancreas and bone intensity.", "width": 1204, "height": 916, "subcaptions": {"a": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74]}, "subfigures": [{"id": "3b9edeb9-d1c4-4bb0-a5c4-7b03d6614f22", "label": "a", "points": [[16.2, 3.5], [16.2, 421.9], [584.9, 421.9], [584.9, 3.5]], "color": "yellow"}, {"id": "7c0793d1-931f-4fa5-9b86-90d0559cb4ba", "label": "a", "points": [[598.2, 7.3], [598.2, 425.7], [1187.8, 425.7], [1187.8, 7.3]], "color": "cyan"}, {"id": "c1140338-48c5-4464-8b84-cdf0ae4494a6", "label": "b", "points": [[12.4, 456.2], [12.4, 867], [588.7, 867], [588.7, 456.2]], "color": "magenta"}, {"id": "03e0dd2f-990b-463e-944e-3b703b3df3ce", "label": "c", "points": 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{"pdf_hash": "8330398d6fba65e0cac3763b593224079987e385", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. HIM-8 is a C2H2 Zinc-Finger Protein that Localizes to Distinct Nuclear Foci during Meiosis (A) Three-dimensional projection through a wild-type gonad stained with DAPI and antibodies against HIM-8. Subnuclear HIM-8 foci are present in all germline nuclei throughout the premeiotic, transition-zone, and pachytene region of the gonad. The transition-zone region outlined by the yellow box is magnified in (B). (B) Prior to meiotic entry, two HIM-8 foci (yellow) are observed in each nucleus. Examples of premeiotic nuclei in which two foci can be clearly observed are outlined in brown circles. Once nuclei have entered the transition zone, representing the leptotene/zygotene stages of meiosis, they usually reveal only a single HIM-8 focus or closely spaced pair of foci. The scale bar represents 5 mm. (C) Schematic representation of the HIM-8 protein. 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{"pdf_hash": "c317759492eee143f342e0baf451885237efc609", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. Case 2: This 42-year-old woman presented with sudden severe headache. (A) The preoperative axial computed tomography (CT) scan shows right-frontal-base hemorrhage. Note that the aneurysm is situated at the site of the hemorrhage. The anterior clinoid process (ACP) is an obstacle to the clipping of an aneurysm. (B) The 3-dimensional (3D) CT angiography shows the superolateral side of the paraclinoid internal carotid artery aneurysm. 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{"pdf_hash": "91533caa1dfbde7bb17f063ceeacd3c78e33a643", "fig_key": "Figure3", "fig_uri": "8-Figure3-1.png", "text": "Figure 3. MMP-targeted imaging of vascular remodeling in abdominal aortic aneurysm. Examples of fused 99m Tc-P805 microSPECT and CT images of matrix metalloproteinase activation in abdominal aortae of a control mouse ((top) row) and animals infused with angiotensin II to induce abdominal aortic aneurysm. A mouse infused with angiotensin II for 4 weeks that developed abdominal aortic aneurysm shows RP805 uptake in the aneurysm ((bottom) row), whereas there is no notable tracer uptake in the abdominal aortae of the control mouse (top row) and an angiotensin II-infused mouse that did not develop aneurysm ((middle) row). T: transvers, C: coronal, S: sagittal. Arrows point to abdominal aortae, identified by CT angiography. Published with permission of Wolters Kluwer Health from \"Imaging vessel wall biology to predict outcome in abdominal aortic aneurysm\", Golestani, R., et al. Circ. Cardiovasc. 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{"pdf_hash": "22b51c83de696d156cd3e73ffd85c6631ddd3e44", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A, T1-weighted coronal magnetic resonance imaging scans with fat saturation and gadolinium enhancement of the superior orbital fissure (lower arrow) and planum sphenoidalis (upper arrow) of a 65-year-old man (case 1). The right optic nerve sheath and orbital apex were enhanced (arrow) and were the site of the third transcranial biopsy (B). 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{"pdf_hash": "d536bfd72dd5c370fe3f0f1983aa2083fc84e9ee", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. OCT images of neointima. (A) Lipidic change. (B) Calcific change. Arrows indicate lipid and calcification within neointima, respectively. OCT = optical coherence tomography.", "width": 1378, "height": 686, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 21, 22, 23, 30], "b": [15, 16, 17, 18, 19, 20, 21, 22, 25, 26, 27, 30]}, "subfigures": [{"id": "2877eb47-ebfa-4bca-bee9-a237ddf0455b", "label": "a", "points": [[1.7, 1.8], [1.7, 681], [683.1, 681], [683.1, 1.8]], "color": "yellow"}, {"id": "07399ae7-6533-45a5-8348-6b83e239f285", "label": "b", "points": [[691.8, -0.4], [691.8, 681], [1370.9, 681], [1370.9, -0.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "OCT", "start": 8, "end": 11, "id": 4}, {"text": "images", "start": 12, "end": 18, "id": 5}, {"text": "of", "start": 19, "end": 21, "id": 6}, {"text": "neointima", "start": 22, "end": 31, "id": 7}, {"text": ".", "start": 31, "end": 32, "id": 8}, {"text": "(", "start": 33, "end": 34, "id": 9}, {"text": "A", "start": 34, "end": 35, "id": 10}, {"text": ")", "start": 35, "end": 36, "id": 11}, {"text": "Lipidic", "start": 37, "end": 44, "id": 12}, {"text": "change", "start": 45, "end": 51, "id": 13}, {"text": ".", "start": 51, "end": 52, "id": 14}, {"text": "(", "start": 53, "end": 54, "id": 15}, {"text": "B", "start": 54, "end": 55, "id": 16}, {"text": ")", "start": 55, "end": 56, "id": 17}, {"text": "Calcific", "start": 57, "end": 65, "id": 18}, {"text": "change", "start": 66, "end": 72, "id": 19}, {"text": ".", "start": 72, "end": 73, "id": 20}, {"text": "Arrows", "start": 74, "end": 80, "id": 21}, {"text": "indicate", "start": 81, "end": 89, "id": 22}, {"text": "lipid", "start": 90, "end": 95, "id": 23}, {"text": "and", "start": 96, "end": 99, "id": 24}, {"text": "calcification", "start": 100, "end": 113, "id": 25}, {"text": "within", "start": 114, "end": 120, "id": 26}, {"text": "neointima", "start": 121, "end": 130, "id": 27}, {"text": ",", "start": 130, "end": 131, "id": 28}, {"text": "respectively", "start": 132, "end": 144, "id": 29}, {"text": ".", "start": 144, "end": 145, "id": 30}, {"text": "OCT", "start": 146, "end": 149, "id": 31}, {"text": "=", "start": 150, "end": 151, "id": 32}, {"text": "optical", "start": 152, "end": 159, "id": 33}, {"text": "coherence", "start": 160, "end": 169, "id": 34}, {"text": "tomography", "start": 170, "end": 180, "id": 35}, {"text": ".", "start": 180, "end": 181, "id": 36}]}
{"pdf_hash": "862e5866a1d233d7977d93c46374195e7b9daa1e", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Fig. 6: a: A pre-contrast T1-weighted image of patient 11 in the sagittal plane. The triangular mass is visible just caudal to the upper canine (small arrows). The dorsal and caudal margins of the mass are indistinct (block arrow). Diagnosis: squamous cell carcinoma. b: Patient 11. Post-contrast T1-weighted image of the same slice does not improve dorsal and caudal delineation of the mass. Notice the normal, moderate homogenous contrast uptake by the nasal turbinates. c: Patient 11. A transverse T2-weighted image of the same tumour clearly shows that there is no extension of the mass into the nasal turbinates (arrows). 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{"pdf_hash": "0adafcc4b4be0584778f39eeb7fcfdc682c8c334", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. The imaging findings of this patient. (A) Many quasi-circular high density nodes on both cerebral hemispheres can be seen using brain computed tomography (CT). (B) Brain magnetic resonance images (MRI) (plain and enhance scan) revealed multiple lesions in the brain. (C) Brain MRI showed the nodes were low density inside whereas high density outside. (D) Brain CT examined on October 18th 2016 showed that focal intracerebral hemorrhage was absorbed. 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{"pdf_hash": "79ddb58774397a15d598f7e241f6b0a3f0facfc3", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: CT scan of the abdomen. (a) Coronal and (b) axial images revealed a large intraperitoneal solid, cystic mass (red arrow) with intralesional calcification and fat, displacing the small bowel loops to the left side of the midline. 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{"pdf_hash": "6b6d43defd7a98368e58c3bf8122e3b1e1e808e9", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Transverse chest CT images of 4 patients who were almost the same height and weight. Images were reconstructed with 30% ASIR. Images are (A) NI = 15, objective image noise 10.95; (B) NI = 20, objective image noise 18.28, (C) NI = 30, objective image noise 28.5, and (D) NI = 40, objective image noise 41.52. 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{"pdf_hash": "081f9a6704c9d9f17030fb24d9ed6db2a676dcc9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Ultrasound appearance of normal healing of a grade II muscle injury (partial tear) at the rectus femoris muscle near the superficial aponeurosis. There is a hypoechoic area filled with fluid (calipers) 3 days after injury (A). Three weeks later, the gap has filled with mildly hypoechoic tissue (asterisk) (B)", "width": 1380, "height": 482, "subcaptions": {"a": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65]}, "subfigures": [{"id": "d987713a-d376-49c8-b2a2-8a0c370ac048", "label": "a", "points": [[9.4, 8.4], [9.4, 448.8], [672.1, 448.8], [672.1, 8.4]], "color": "yellow"}, {"id": "7ebdaea7-6688-4432-b60c-344bf5c209ef", "label": "b", "points": [[689.6, 1.9], [689.6, 459.7], [1376.3, 459.7], [1376.3, 1.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Ultrasound", "start": 8, "end": 18, "id": 4}, {"text": "appearance", "start": 19, "end": 29, "id": 5}, {"text": "of", "start": 30, "end": 32, "id": 6}, {"text": "normal", "start": 33, "end": 39, "id": 7}, {"text": "healing", "start": 40, "end": 47, "id": 8}, {"text": "of", "start": 48, "end": 50, "id": 9}, {"text": "a", "start": 51, "end": 52, "id": 10}, {"text": "grade", "start": 53, "end": 58, "id": 11}, {"text": "II", "start": 59, "end": 61, "id": 12}, {"text": "muscle", "start": 62, "end": 68, "id": 13}, {"text": "injury", "start": 69, "end": 75, "id": 14}, {"text": "(", "start": 76, "end": 77, "id": 15}, {"text": "partial", "start": 77, "end": 84, "id": 16}, {"text": "tear", "start": 85, "end": 89, "id": 17}, {"text": ")", "start": 89, "end": 90, "id": 18}, {"text": "at", "start": 91, "end": 93, "id": 19}, {"text": "the", "start": 94, "end": 97, "id": 20}, {"text": "rectus", "start": 98, "end": 104, "id": 21}, {"text": "femoris", "start": 105, "end": 112, "id": 22}, {"text": "muscle", "start": 113, "end": 119, "id": 23}, {"text": "near", "start": 120, "end": 124, "id": 24}, {"text": "the", "start": 125, "end": 128, "id": 25}, {"text": "superficial", "start": 129, "end": 140, "id": 26}, {"text": "aponeurosis", "start": 141, "end": 152, "id": 27}, {"text": ".", "start": 152, "end": 153, "id": 28}, {"text": "There", "start": 154, "end": 159, "id": 29}, {"text": "is", "start": 160, "end": 162, "id": 30}, {"text": "a", "start": 163, "end": 164, "id": 31}, {"text": "hypoechoic", "start": 165, "end": 175, "id": 32}, {"text": "area", "start": 176, "end": 180, "id": 33}, {"text": "filled", "start": 181, "end": 187, "id": 34}, {"text": "with", "start": 188, "end": 192, "id": 35}, {"text": "fluid", "start": 193, "end": 198, "id": 36}, {"text": "(", "start": 199, "end": 200, "id": 37}, {"text": "calipers", "start": 200, "end": 208, "id": 38}, {"text": ")", "start": 208, "end": 209, "id": 39}, {"text": "3", "start": 210, "end": 211, "id": 40}, {"text": "days", "start": 212, "end": 216, "id": 41}, {"text": "after", "start": 217, "end": 222, "id": 42}, {"text": "injury", "start": 223, "end": 229, "id": 43}, {"text": "(", "start": 230, "end": 231, "id": 44}, {"text": "A", "start": 231, "end": 232, "id": 45}, {"text": ")", "start": 232, "end": 233, "id": 46}, {"text": ".", "start": 233, "end": 234, "id": 47}, {"text": "Three", "start": 235, "end": 240, "id": 48}, {"text": "weeks", "start": 241, "end": 246, "id": 49}, {"text": "later", "start": 247, "end": 252, "id": 50}, {"text": ",", "start": 252, "end": 253, "id": 51}, {"text": "the", "start": 254, "end": 257, "id": 52}, {"text": "gap", "start": 258, "end": 261, "id": 53}, {"text": "has", "start": 262, "end": 265, "id": 54}, {"text": "filled", "start": 266, "end": 272, "id": 55}, {"text": "with", "start": 273, "end": 277, "id": 56}, {"text": "mildly", "start": 278, "end": 284, "id": 57}, {"text": "hypoechoic", "start": 285, "end": 295, "id": 58}, {"text": "tissue", "start": 296, "end": 302, "id": 59}, {"text": "(", "start": 303, "end": 304, "id": 60}, {"text": "asterisk", "start": 304, "end": 312, "id": 61}, {"text": ")", "start": 312, "end": 313, "id": 62}, {"text": "(", "start": 314, "end": 315, "id": 63}, {"text": "B", "start": 315, "end": 316, "id": 64}, {"text": ")", "start": 316, "end": 317, "id": 65}]}
{"pdf_hash": "24bb17845970a8ba941ce0b00f1ad396437c9562", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: A 31-year-old man with 22q11.2 deletion syndrome who presented for evaluation of vascular anomalies. (a) Contrast-enhanced computed tomography of the thorax axial image demonstrates the main pulmonary trunk (P) giving rise to the right pulmonary artery (R) with the absence of the left pulmonary artery and hypertrophied collateral left bronchial artery (black arrow). (b) Computed tomography axial image demonstrates a right-sided aortic arch (A) and hypertrophied collateral left intercostal arteries (white arrow heads) and bronchial artery (white arrow) supplying the left lung. (c) Computed tomography axial image in lung window shows reticular opacities penetrating the peripheral left lung parenchyma representing intercostal artery collaterals (arrows). The left lung is slightly smaller compared to the right. 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{"pdf_hash": "e3fed15f531cb85cee06e293bd37118d660168a4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: (A and B) Transthoracic echocardiography and transoesophageal echocardiography showing the mass over the pulmonary valve (PV) (arrow). (C) Cardiac magnetic resonance (CMR) (Discovery 450, General Electric Healthcare, 1.5 T Unit, Milwaukee, WI, USA) scan images showing a spherical mass (arrow), 8\u00d77.5 mm in dimension, attached to the anterior leaflet of the PV. The papillary fibroelastoma (PFE) appears hypointense compared with heart chambers in this steady-state free precession sequence. 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{"pdf_hash": "0d28018a7abbc017bacf216120644d8cfd1e8075", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5 Lateral knee x ray of (A) patient 3a at 20 years and (B) patient 5b at 28 years showing a double layered patella. Persistence of this finding into adulthood indicates a true anatomical variant and is a useful diagnostic clue.", "width": 972, "height": 642, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14], "b": [16, 17, 18, 19, 20, 21, 22, 23]}, "subfigures": [{"id": "966b1242-4ecd-4037-b7b2-329377ad6353", "label": "a", "points": [[29.6, 1.3], [29.6, 601.7], [481.1, 601.7], [481.1, 1.3]], "color": "yellow"}, {"id": "20ff2eb3-0f39-47bc-b67d-7351bfe213cd", "label": "b", "points": [[491.8, 5.9], [491.8, 601.7], [960.1, 601.7], [960.1, 5.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": "Lateral", "start": 9, "end": 16, "id": 2}, {"text": "knee", "start": 17, "end": 21, "id": 3}, {"text": "x", "start": 22, "end": 23, "id": 4}, {"text": "ray", "start": 24, "end": 27, "id": 5}, {"text": "of", "start": 28, "end": 30, "id": 6}, {"text": "(", "start": 31, "end": 32, "id": 7}, {"text": "A", "start": 32, "end": 33, "id": 8}, {"text": ")", "start": 33, "end": 34, "id": 9}, {"text": "patient", "start": 35, "end": 42, "id": 10}, {"text": "3a", "start": 43, "end": 45, "id": 11}, {"text": "at", "start": 46, "end": 48, "id": 12}, {"text": "20", "start": 49, "end": 51, "id": 13}, {"text": "years", "start": 52, "end": 57, "id": 14}, {"text": "and", "start": 58, "end": 61, "id": 15}, {"text": "(", "start": 62, "end": 63, "id": 16}, {"text": "B", "start": 63, "end": 64, "id": 17}, {"text": ")", "start": 64, "end": 65, "id": 18}, {"text": "patient", "start": 66, "end": 73, "id": 19}, {"text": "5b", "start": 74, "end": 76, "id": 20}, {"text": "at", "start": 77, "end": 79, "id": 21}, {"text": "28", "start": 80, "end": 82, "id": 22}, {"text": "years", "start": 83, "end": 88, "id": 23}, {"text": "showing", "start": 89, "end": 96, "id": 24}, {"text": "a", "start": 97, "end": 98, "id": 25}, {"text": "double", "start": 99, "end": 105, "id": 26}, {"text": "layered", "start": 106, "end": 113, "id": 27}, {"text": "patella", "start": 114, "end": 121, "id": 28}, {"text": ".", "start": 121, "end": 122, "id": 29}, {"text": "Persistence", "start": 123, "end": 134, "id": 30}, {"text": "of", "start": 135, "end": 137, "id": 31}, {"text": "this", "start": 138, "end": 142, "id": 32}, {"text": "finding", "start": 143, "end": 150, "id": 33}, {"text": "into", "start": 151, "end": 155, "id": 34}, {"text": "adulthood", "start": 156, "end": 165, "id": 35}, {"text": "indicates", "start": 166, "end": 175, "id": 36}, {"text": "a", "start": 176, "end": 177, "id": 37}, {"text": "true", "start": 178, "end": 182, "id": 38}, {"text": "anatomical", "start": 183, "end": 193, "id": 39}, {"text": "variant", "start": 194, "end": 201, "id": 40}, {"text": "and", "start": 202, "end": 205, "id": 41}, {"text": "is", "start": 206, "end": 208, "id": 42}, {"text": "a", "start": 209, "end": 210, "id": 43}, {"text": "useful", "start": 211, "end": 217, "id": 44}, {"text": "diagnostic", "start": 218, "end": 228, "id": 45}, {"text": "clue", "start": 229, "end": 233, "id": 46}, {"text": ".", "start": 233, "end": 234, "id": 47}]}
{"pdf_hash": "3d5d3c96a23816151899c7828bb74e971a142b60", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. (A-D) Imaging studies showing midline and intraauricular malformations. (A) Magnetic resonance imaging (MRI) (axial T1 with gadolinium) at 14 years of age, showing hypoplastic lateral and posterior semicircular canals (long arrows) and dysplastic vestibule (short arrow). (B) MRI at 14 years of age, showing Mondini dysplasia of the partition of the cochlea. (C) MRI at 14 years of age, showing decreased anterior pituitary volume (160 mm3). (D) MRI at 14 years of age, showing olfactory bulb aplasia (R) and hypoplasia (L). 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{"pdf_hash": "10a72c73451df16ff3d651f8b4b1d7724864e13e", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. Methylated arginine 17 on histone H3. Light and fluorescent micrographs of mouse immature oocytes, fertilized eggs and early embryonic stages stained for the Me(Arg17)H3 modification (F-J, red) and nucleic acid (K-O, green). (A,F,K) Immature oocyte nuclei displayed high levels of this modification in a punctate manner throughout the entire nuclear region excluding the nucleolus. (B,G,L) At fertilization, diffuse punctate cytoplasmic Me(Arg17)H3 staining is seen with no apparent staining observed on the metaphase plate (asterisks). (C,H,M) At the pronuclear stage, however, the modification is associated with chromatin in both pronuclei at similar levels. In all of the subsequent developmental stages tested, punctate cytoplasmic staining with little or no chromatin staining is observed in metaphase stage blastomeres (J, O, arrows). There is also little or no staining in anaphase stage blastomeres (I, N, arrows). This modification also stains cumulus cell nuclei and only stains polar bodies faintly (data not shown). 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{"pdf_hash": "09a5ea4f1d0700636536376a580c2edc4012464d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Pictures after the nasal intubation of a 61-year-old man with schizophrenia who drank hot water estimated to be 90\u00b0C. A, The larynx as observed using a bronchoscope immediately after intubation. B, Computed tomography of the larynx area, showing the intubation tube (yellow arrow). 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{"pdf_hash": "c3f9a299beff46645eeb9889dac89cee0ecbf725", "fig_key": "Figure5", "fig_uri": "8-Figure5-1.png", "text": "Figure 5 Marked reduction in extent of gadolinium enhancement following immunotherapy in Patient 2. Axial T 1 MRI brain with gadolinium. (A) At time of relapse, off of all immunosuppressive therapy and prior to brain biopsy. (B) Near complete resolution of gadolinium enhancing lesions following chronic oral prednisone. (C) Recurrent gadolinium enhancing lesions following discontinuation of prednisone. 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Multiple nodules with ground glass opacity halo in the left upper lung field (A) and ill defined patches of nodular ground glass opacity are shown in the right middle (B) and the right lower lung field (C, D), which involve mainly the peripheral regions of the both lungs (arrows).", "width": 1378, "height": 984, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "10ea4e75-09c2-4a5e-b373-43963902d2a0", "label": "a", "points": [[5.4, 4.4], [5.4, 485.5], [684.7, 485.5], [684.7, 4.4]], "color": "yellow"}, {"id": "f84496a9-5b70-4446-b7d2-8ad2c9888d33", "label": "b", "points": [[699.9, 4.4], [699.9, 489.8], [1372.6, 489.8], [1372.6, 4.4]], "color": "cyan"}, {"id": "fc586725-92fc-4587-ae5b-a023ee75df58", "label": "c", "points": [[9.8, 502.9], [9.8, 977.5], [682.5, 977.5], 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{"pdf_hash": "0fc7815810714ec3d6ae3dc007b5534af2053bac", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Microcrystalline Au deposited on glass. (a) Standard BSE imaging at 6 keV; (b) Sample in 1 kV/mm, landing energy of electrons 5 eV.", "width": 814, "height": 426, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34]}, "subfigures": [{"id": "1d6b07da-b739-4cfa-a160-e82f35bae19e", "label": "a", "points": [[5.4, 0.4], [5.4, 422.2], [401.4, 422.2], [401.4, 0.4]], "color": "yellow"}, {"id": "421d22b5-fc24-4d1f-b27a-1738414f8d1d", "label": "b", "points": [[410.4, 3], [410.4, 418.4], [811.7, 418.4], [811.7, 3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Microcrystalline", "start": 10, "end": 26, "id": 3}, {"text": "Au", "start": 27, "end": 29, "id": 4}, {"text": "deposited", "start": 30, "end": 39, "id": 5}, {"text": "on", "start": 40, "end": 42, "id": 6}, {"text": "glass", "start": 43, "end": 48, "id": 7}, {"text": ".", "start": 48, "end": 49, "id": 8}, {"text": "(", "start": 50, "end": 51, "id": 9}, {"text": "a", "start": 51, "end": 52, "id": 10}, {"text": ")", "start": 52, "end": 53, "id": 11}, {"text": "Standard", "start": 54, "end": 62, "id": 12}, {"text": "BSE", "start": 63, "end": 66, "id": 13}, {"text": "imaging", "start": 67, "end": 74, "id": 14}, {"text": "at", "start": 75, "end": 77, "id": 15}, {"text": "6", "start": 78, "end": 79, "id": 16}, {"text": "keV", "start": 80, "end": 83, "id": 17}, {"text": ";", "start": 83, "end": 84, "id": 18}, {"text": "(", "start": 85, "end": 86, "id": 19}, {"text": "b", "start": 86, "end": 87, "id": 20}, {"text": ")", "start": 87, "end": 88, "id": 21}, {"text": "Sample", "start": 89, "end": 95, "id": 22}, {"text": "in", "start": 96, "end": 98, "id": 23}, {"text": "1", "start": 99, "end": 100, "id": 24}, {"text": "kV", "start": 101, "end": 103, "id": 25}, {"text": "/", "start": 103, "end": 104, "id": 26}, {"text": "mm", "start": 104, "end": 106, "id": 27}, {"text": ",", "start": 106, "end": 107, "id": 28}, {"text": "landing", "start": 108, "end": 115, "id": 29}, {"text": "energy", "start": 116, "end": 122, "id": 30}, {"text": "of", "start": 123, "end": 125, "id": 31}, {"text": "electrons", "start": 126, "end": 135, "id": 32}, {"text": "5", "start": 136, "end": 137, "id": 33}, {"text": "eV.", "start": 138, "end": 141, "id": 34}]}
{"pdf_hash": "6e6f9b1dfae4e622ab69b2a4860d74d9b809e487", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Fig. 5 A 70-year-old woman with a sclerotic bone metastasis of breast cancer in thoracic vertebral body 10. a PET image reconstructed using the standard CTACmap shows an FDG-avid lesion in the left anterior aspect of T10. b Standard CTAC map shows that the bone lesion is sclerotic. c PET image reconstructed using the modified CT AC map. d In the modified CT AC map bone is substituted by soft tissue. 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{"pdf_hash": "089ef607f76fe0ad30ce0cbdda2310825afb499e", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. a , b A 66-year-old Caucasian man presented with a right facial capillary malformation and a left orange-colored choroidal mass. c \u2013 e The lesion is hyperautofluorescent and hypofluorescent on fluorescein indocyanine green angiography. f On B-scan ultrasound, the lesion is bilobed, echodense and measures 6.0 mm in apical height and 16.3 mm in its greatest basal dimension. 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{"pdf_hash": "7765deeb217b5250965e5edc7ef076028e017905", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Converging genual and perigenual abnormalities in borderline personality disorder. An overlap of several contrasts involving medial-frontal abnormalities are shown in sagittal (A) and axial (B) slices. White matter alterations in fractional anisotropy shown in blue enclose medial clusters of: 1) altered mean diffusivity shown in red, 2) abnormal global brain connectivity shown in green, and 3) a small region of increased connectivity with the left amygdala (cluster of abnormal amplitude of lowfrequency fluctuations), which is shown in purple (p corrected , .05) with an enlarged version (p uncorrected , .001) shown in yellow.", "width": 1042, "height": 768, "subcaptions": {"a": [26, 27, 28, 29], "b": [31, 32, 33, 34]}, "subfigures": [{"id": "e76bcedb-b99c-4e52-8b1c-7d019f65734c", "label": "a", "points": [[9.9, 1.6], [9.9, 353.9], [1012.4, 353.9], [1012.4, 1.6]], "color": "yellow"}, {"id": "aa4e556e-bd24-493a-9cc7-3c7b8f3e0ea8", "label": "b", "points": [[893.9, 362.2], [893.9, 767.1], [100.4, 767.1], [100.4, 362.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 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{"pdf_hash": "0da1083a20ffed8ce2537a54e553cd1b5e88b8b9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A well circumscribed enhancing neoplasm involving the vermis and 4th ventricle was present (Sagittal T1-weighted MR (a). Microcalcifications were also present on histologic examination (b). The neoplasm was lobulated and low grade with round to oval cells reminiscent of pilocytic astrocytoma (c). In addition distinctive rosettes reflecting neuronal differentiation were present (d). Synaptophysin was strongly expressed in rosettes and perivascular pseudorosettes (e). 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{"pdf_hash": "6efc4a6ed1d58dc760b49af9d6e7fd379d30a1ff", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: Preoperative T1 axial magnetic resonance images, both noncontrast enhanced (a) and contrast enhanced (b) images, showing choroid plexus tissue protruding from foramen of Luschka", "width": 674, "height": 590, "subcaptions": {"a": [11, 12, 13, 14, 15], "b": [17, 18, 19, 20, 21], "c": [0]}, "subfigures": [{"id": "2d3442fd-d29e-4a32-b1ae-c3db32eb6c2a", "label": "a", "points": [[3.8, 2], [3.8, 387.4], [324.3, 387.4], [324.3, 2]], "color": "yellow"}, {"id": "d21504b2-e0a2-4b09-9cd9-6efb0da26373", "label": "b", "points": [[333.8, 3], [333.8, 387.4], [670.3, 387.4], [670.3, 3]], "color": "cyan"}, {"id": "172aeda7-304f-4b78-970d-acfdb44b0eb6", "label": "c", "points": [[11.2, 392.2], [11.2, 557.2], [666, 557.2], [666, 392.2]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Preoperative", "start": 10, "end": 22, "id": 3}, {"text": "T1", "start": 23, "end": 25, "id": 4}, {"text": "axial", "start": 26, "end": 31, "id": 5}, {"text": "magnetic", "start": 32, "end": 40, "id": 6}, {"text": "resonance", "start": 41, "end": 50, "id": 7}, {"text": "images", "start": 51, "end": 57, "id": 8}, {"text": ",", "start": 57, "end": 58, "id": 9}, {"text": "both", "start": 59, "end": 63, "id": 10}, {"text": "noncontrast", "start": 64, "end": 75, "id": 11}, {"text": "enhanced", "start": 76, "end": 84, "id": 12}, {"text": "(", "start": 85, "end": 86, "id": 13}, {"text": "a", "start": 86, "end": 87, "id": 14}, {"text": ")", "start": 87, "end": 88, "id": 15}, {"text": "and", "start": 89, "end": 92, "id": 16}, {"text": "contrast", "start": 93, "end": 101, "id": 17}, {"text": "enhanced", "start": 102, "end": 110, "id": 18}, {"text": "(", "start": 111, "end": 112, "id": 19}, {"text": "b", "start": 112, "end": 113, "id": 20}, {"text": ")", "start": 113, "end": 114, "id": 21}, {"text": "images", "start": 115, "end": 121, "id": 22}, {"text": ",", "start": 121, "end": 122, "id": 23}, {"text": "showing", "start": 123, "end": 130, "id": 24}, {"text": "choroid", "start": 131, "end": 138, "id": 25}, {"text": "plexus", "start": 139, "end": 145, "id": 26}, {"text": "tissue", "start": 146, "end": 152, "id": 27}, {"text": "protruding", "start": 153, "end": 163, "id": 28}, {"text": "from", "start": 164, "end": 168, "id": 29}, {"text": "foramen", "start": 169, "end": 176, "id": 30}, {"text": "of", "start": 177, "end": 179, "id": 31}, {"text": "Luschka", "start": 180, "end": 187, "id": 32}]}
{"pdf_hash": "53759a4b17212d66c7a76b6ed2d436ce638b029b", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: T2-weighed magnetic resonance imaging at 9 (a, b) and 32 (c, d) weeks of gestation. (a) Bilateral pelvic masses with a horizontal view. A right-sided multilocular mass (arrow) and left-sided unilocular mass (asterisk) are shown. We suspected bilateral ovarian tumors at this point. (b) Sagittal view. The left-sided unilocular mass (asterisk) is shown. (c) Horizontal view. The right-sided multilocular mass (arrow) is involved in or at least is located very close to the large mass (star). (d) Sagittal view. 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{"pdf_hash": "d0a33ec2d8d7789cda4e26751d89db00b854ea9a", "fig_key": "Figure8", "fig_uri": "10-Figure8-1.png", "text": "Fig 8. Enlarged ventricular dimensions in peke-face Persians. MRI midsagittal (A, D), dorsal (B, E), and transversal (C, F) T2-weighted MR-images of three peke-face Persians (A, B: 2 years old, female; B, C: 5 years old male; C, D: 2 years old, female). Images reveal severe dilatation of the lateral ventricles, reduction, and destruction of the cerebral parenchyma, as well as severe cerebellar herniation into the vertebral canal.", "width": 1336, "height": 1162, "subcaptions": {"a": [12, 13, 14, 15, 18, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 48, 49, 50, 51, 52, 53, 73, 74], "b": [12, 20, 21, 22, 25, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 47, 48, 49, 50, 51, 52, 53, 54, 55, 58, 59, 60, 61, 62, 73, 74], "c": [12, 28, 29, 30, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 57, 58, 59, 60, 61, 62, 63, 64, 67, 68, 69, 70, 71, 72, 73, 74], "d": [12, 13, 14, 17, 18, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 66, 67, 68, 69, 70, 71, 72, 73, 74], "e": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 12, 74, 20, 21, 24, 25], "f": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 12, 74, 28, 29]}, "subfigures": [{"id": "7a4d79de-8643-4674-813b-aacadf4010ab", "label": "a", "points": [[20.1, 1.8], [20.1, 392.2], [514, 392.2], [514, 1.8]], 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{"pdf_hash": "9b5556f10afe39584e4d0a1a0e429d3d33722a92", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Figure 6. PET scan. A \u2013 Nodular hyperfixation area of FDG on the remaining parenchyma (white arrow); B \u2013 At 1 year and 4 months follow-up, the PET-CT scan showing no signs of disease relapse.", "width": 1160, "height": 484, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "1093b4ea-8e30-467e-9d02-3f73b3c37070", "label": "a", "points": [[32.1, -0.3], [32.1, 448.7], [558.1, 448.7], [558.1, -0.3]], "color": "yellow"}, {"id": "7f5e6349-efee-4e44-909f-dbd6cdcfa8a6", "label": "b", "points": [[576.4, 5.2], [576.4, 448.7], [1118.8, 448.7], [1118.8, 5.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "PET", "start": 10, "end": 13, "id": 3}, {"text": "scan", "start": 14, "end": 18, "id": 4}, {"text": ".", "start": 18, "end": 19, "id": 5}, {"text": "A", "start": 20, "end": 21, "id": 6}, {"text": "\u2013", "start": 22, "end": 23, "id": 7}, {"text": "Nodular", "start": 24, "end": 31, "id": 8}, {"text": "hyperfixation", "start": 32, "end": 45, "id": 9}, {"text": "area", "start": 46, "end": 50, "id": 10}, {"text": "of", "start": 51, "end": 53, "id": 11}, {"text": "FDG", "start": 54, "end": 57, "id": 12}, {"text": "on", "start": 58, "end": 60, "id": 13}, {"text": "the", "start": 61, "end": 64, "id": 14}, {"text": "remaining", "start": 65, "end": 74, "id": 15}, {"text": "parenchyma", "start": 75, "end": 85, "id": 16}, {"text": "(", "start": 86, "end": 87, "id": 17}, {"text": "white", "start": 87, "end": 92, "id": 18}, {"text": "arrow", "start": 93, "end": 98, "id": 19}, {"text": ")", "start": 98, "end": 99, "id": 20}, {"text": ";", "start": 99, "end": 100, "id": 21}, {"text": "B", "start": 101, "end": 102, "id": 22}, {"text": "\u2013", "start": 103, "end": 104, "id": 23}, {"text": "At", "start": 105, "end": 107, "id": 24}, {"text": "1", "start": 108, "end": 109, "id": 25}, {"text": "year", "start": 110, "end": 114, "id": 26}, {"text": "and", "start": 115, "end": 118, "id": 27}, {"text": "4", "start": 119, "end": 120, "id": 28}, {"text": "months", "start": 121, "end": 127, "id": 29}, {"text": "follow", "start": 128, "end": 134, "id": 30}, {"text": "-", "start": 134, "end": 135, "id": 31}, {"text": "up", "start": 135, "end": 137, "id": 32}, {"text": ",", "start": 137, "end": 138, "id": 33}, {"text": "the", "start": 139, "end": 142, "id": 34}, {"text": "PET", "start": 143, "end": 146, "id": 35}, {"text": "-", "start": 146, "end": 147, "id": 36}, {"text": "CT", "start": 147, "end": 149, "id": 37}, {"text": "scan", "start": 150, "end": 154, "id": 38}, {"text": "showing", "start": 155, "end": 162, "id": 39}, {"text": "no", "start": 163, "end": 165, "id": 40}, {"text": "signs", "start": 166, "end": 171, "id": 41}, {"text": "of", "start": 172, "end": 174, "id": 42}, {"text": "disease", "start": 175, "end": 182, "id": 43}, {"text": "relapse", "start": 183, "end": 190, "id": 44}, {"text": ".", "start": 190, "end": 191, "id": 45}]}
{"pdf_hash": "74714b3e323e7e23ff23fb052398e4fea60c8f9e", "fig_key": "Figure8", "fig_uri": "13-Figure8-1.png", "text": "FIG. 8. Simulation results for dual-object cases [unit used for columns (a)-(d): 10 \u22123 mm \u22121 ]. Column (a) set values; column (b) reconstruction based on the baseline method; column (c) reconstruction based on the reference-compensation method; column (d) reconstruction based on the GSD method; column (e) normalized contour plots along the dotted loops marked in columns (b)-(d). The shaded areas in column (e) indicate the object locations corresponding to those marked in column (a). Note that although the widths of the object remain constant for all three depth, the radial expansion represented by the shaded areas in column (d) decreases with respect to imaging depth. The dotted circles in column (d) indicate the object locations corresponding to those marked in column (a). The \"err\"s in subfigures of columns (b)-(d) represent the standard deviation of the reconstruction errors averaged by the number of components in the objective function. 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{"pdf_hash": "01213b8e91b5868efdaa9b1288945b19af2794eb", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4 MRI (at 3 T) of a 69-year-old female patient with a pT3 TCC of the bladder. (A) On the DW-MR image at a b value of 1000 s/mm 2 the tumour is seen as thickening of the anterior bladder wall with high signal intensity and with irregular outer margins extending into the surrounding fat tissue (arrows). (B) On the corresponding ADC map the tumour is visualized as thickening of the bladder wall with impeded diffusion, represented by colour shades of dark grey (arrows).", "width": 624, "height": 904, "subcaptions": {"a": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71], "b": [72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104]}, "subfigures": [{"id": "40318f8b-e078-49b9-9030-0e76b699e766", "label": "a", "points": [[52, 25.8], [52, 456.8], [589, 456.8], [589, 25.8]], "color": "yellow"}, {"id": "6713bd9a-04c0-46b9-ba9d-1713ed5a611d", "label": "b", "points": [[54, 472.8], [54, 901.9], [588, 901.9], [588, 472.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "MRI", 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{"pdf_hash": "6c71dc8e403a4297e0caafec6ccee1f1cffa70d5", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Immunohistochemical images of HNSCC with focal expression of stem cell markers and MIB1 (arrows): membrane staining using the anti-CD44 antibody (A), membrane staining using anti-CD24 antibody (B), membrane staining using anti-integrin-b1 antibody (C), cytoplasmic staining using the antiOct4 antobody (D), cytoplasmic staining using the anti-ALDH1 antibody (E) and nuclear staining using the MIB1 antibody (F).", "width": 1074, "height": 850, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 31], "c": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "d": [55, 56, 57, 58, 59, 60, 61, 62, 63], "e": [65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75], "f": [77, 78, 79, 80, 81, 82, 83, 84, 85]}, "subfigures": [{"id": "24fb249f-316b-4997-b900-76cb67dcf665", "label": "a", "points": [[48, 6.6], [48, 398.5], [355.1, 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{"pdf_hash": "60957aaa47182a78e4858feb6a8beff9ed2f29af", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Representative images of radiologic and macroscopic findings of a right testicular mass. Computed tomography (A) and ultrasound imaging (B) present a cystic mass (arrow in A) suspected to have a tumorous condition. (C) Surgical specimen reveals a mass with a unilocular cyst filled with mucinous materials.", "width": 1170, "height": 958, "subcaptions": {"a": [17, 18, 19, 20, 21, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "b": [37, 38, 39, 40, 41, 42, 43, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "0a6031e1-13ab-4f87-b286-d4e79fb93f5e", "label": "a", "points": [[37.3, 8], [37.3, 392.5], [584.4, 392.5], [584.4, 8]], "color": "yellow"}, {"id": "a6ed51e6-b071-4f82-b2ac-cb216cc595fd", "label": "b", "points": [[591.8, 8], [591.8, 394.3], [1133.4, 394.3], [1133.4, 8]], "color": "cyan"}, {"id": "f8239289-0aa5-45c4-8cbd-74449fd7c6a6", "label": "c", "points": [[42.8, 401.7], [42.8, 917.4], [1137.1, 917.4], [1137.1, 401.7]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Representative", "start": 8, "end": 22, "id": 4}, {"text": "images", "start": 23, "end": 29, "id": 5}, {"text": "of", "start": 30, "end": 32, "id": 6}, {"text": "radiologic", "start": 33, "end": 43, "id": 7}, {"text": "and", "start": 44, "end": 47, "id": 8}, {"text": "macroscopic", "start": 48, "end": 59, "id": 9}, {"text": "findings", "start": 60, "end": 68, "id": 10}, {"text": "of", "start": 69, "end": 71, "id": 11}, {"text": "a", "start": 72, "end": 73, "id": 12}, {"text": "right", "start": 74, "end": 79, "id": 13}, {"text": "testicular", "start": 80, "end": 90, "id": 14}, {"text": "mass", "start": 91, "end": 95, "id": 15}, {"text": ".", "start": 95, "end": 96, "id": 16}, {"text": "Computed", "start": 97, "end": 105, "id": 17}, {"text": "tomography", "start": 106, "end": 116, "id": 18}, {"text": "(", "start": 117, "end": 118, "id": 19}, {"text": "A", "start": 118, "end": 119, "id": 20}, {"text": ")", "start": 119, "end": 120, "id": 21}, {"text": "and", "start": 121, "end": 124, "id": 22}, {"text": "ultrasound", "start": 125, "end": 135, "id": 23}, {"text": "imaging", "start": 136, "end": 143, "id": 24}, {"text": "(", "start": 144, "end": 145, "id": 25}, {"text": "B", "start": 145, "end": 146, "id": 26}, {"text": ")", "start": 146, "end": 147, "id": 27}, {"text": "present", "start": 148, "end": 155, "id": 28}, {"text": "a", "start": 156, "end": 157, "id": 29}, {"text": "cystic", "start": 158, "end": 164, "id": 30}, {"text": "mass", "start": 165, "end": 169, "id": 31}, {"text": "(", "start": 170, "end": 171, "id": 32}, {"text": "arrow", "start": 171, "end": 176, "id": 33}, {"text": "in", "start": 177, "end": 179, "id": 34}, {"text": "A", "start": 180, "end": 181, "id": 35}, {"text": ")", "start": 181, "end": 182, "id": 36}, {"text": "suspected", "start": 183, "end": 192, "id": 37}, {"text": "to", "start": 193, "end": 195, "id": 38}, {"text": "have", "start": 196, "end": 200, "id": 39}, {"text": "a", "start": 201, "end": 202, "id": 40}, {"text": "tumorous", "start": 203, "end": 211, "id": 41}, {"text": "condition", "start": 212, "end": 221, "id": 42}, {"text": ".", "start": 221, "end": 222, "id": 43}, {"text": "(", "start": 223, "end": 224, "id": 44}, {"text": "C", "start": 224, "end": 225, "id": 45}, {"text": ")", "start": 225, "end": 226, "id": 46}, {"text": "Surgical", "start": 227, "end": 235, "id": 47}, {"text": "specimen", "start": 236, "end": 244, "id": 48}, {"text": "reveals", "start": 245, "end": 252, "id": 49}, {"text": "a", "start": 253, "end": 254, "id": 50}, {"text": "mass", "start": 255, "end": 259, "id": 51}, {"text": "with", "start": 260, "end": 264, "id": 52}, {"text": "a", "start": 265, "end": 266, "id": 53}, {"text": "unilocular", "start": 267, "end": 277, "id": 54}, {"text": "cyst", "start": 278, "end": 282, "id": 55}, {"text": "filled", "start": 283, "end": 289, "id": 56}, {"text": "with", "start": 290, "end": 294, "id": 57}, {"text": "mucinous", "start": 295, "end": 303, "id": 58}, {"text": "materials", "start": 304, "end": 313, "id": 59}, {"text": ".", "start": 313, "end": 314, "id": 60}]}
{"pdf_hash": "16d0d3419bf25fc8fd8678bcae3387197570c54e", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3: Presurgical screening coronary computed tomography angiography (RR interval = 1114 ms) performed in Target CTA mode on a 61-year-old male with a history of aortic valve replacement. Curved multiplanar reconstruction images show the right coronary (a) and left anterior descending arteries (b) with minimal motion artifacts. The diagnostic phase was 68% for calcium scoring scan and 69.1% for coronary computed tomography angiography. 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{"pdf_hash": "f2095a26501e28c60da222344add146b5b38d5c3", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig 1. Variation in X-ray digital radiography with respect to Beijing-You foot polydactyly. A-D show the different foot phenotypes of Beijing-You chicken, E-H show the X-ray digital radiography coordinately with A-D. A & E: non-polydactylous foot with four digits, identified from anterior to posterior (1, 2, 3, 4). B & F: Beijing-You foot with four digits, with a polyphalange in digit \"1\" making it digit \"2\" (2, 2, 3, 4). C & G: polydactylous Beijing-You foot with five digits (2, 1, 2, 3, 4). 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{"pdf_hash": "1e2bce3947d4c03a181a86a27c334064184b8fca", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig 2. Duplex ultrasound of right vertebral artery: a) before percutaneous transluminal angioplasty showing partial steal phenomonenon - retrograde flow through right vertebral artery during systole (arrow); b) after percutaneous transluminal angioplasty showing normal waveforms (arrow).", "width": 1000, "height": 366, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "4b13d8dc-a2e3-4569-ad93-620c567dd9d8", "label": "a", "points": [[5.5, 1.6], [5.5, 333.3], [462.1, 333.3], [462.1, 1.6]], "color": "yellow"}, {"id": "5f64bfff-8f5e-4d3b-be3e-026da1a98654", "label": "b", "points": [[683.3, 3.2], [683.3, 333.3], [999.2, 333.3], [999.2, 3.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Duplex", "start": 7, "end": 13, "id": 3}, {"text": "ultrasound", "start": 14, "end": 24, "id": 4}, {"text": "of", "start": 25, "end": 27, "id": 5}, {"text": "right", "start": 28, "end": 33, "id": 6}, {"text": "vertebral", "start": 34, "end": 43, "id": 7}, {"text": "artery", "start": 44, "end": 50, "id": 8}, {"text": ":", "start": 50, "end": 51, "id": 9}, {"text": "a", "start": 52, "end": 53, "id": 10}, {"text": ")", "start": 53, "end": 54, "id": 11}, {"text": "before", "start": 55, "end": 61, "id": 12}, {"text": "percutaneous", "start": 62, "end": 74, "id": 13}, {"text": "transluminal", "start": 75, "end": 87, "id": 14}, {"text": "angioplasty", "start": 88, "end": 99, "id": 15}, {"text": "showing", "start": 100, "end": 107, "id": 16}, {"text": "partial", "start": 108, "end": 115, "id": 17}, {"text": "steal", "start": 116, "end": 121, "id": 18}, {"text": "phenomonenon", "start": 122, "end": 134, "id": 19}, {"text": "-", "start": 135, "end": 136, "id": 20}, {"text": "retrograde", "start": 137, "end": 147, "id": 21}, {"text": "flow", "start": 148, "end": 152, "id": 22}, {"text": "through", "start": 153, "end": 160, "id": 23}, {"text": "right", "start": 161, "end": 166, "id": 24}, {"text": "vertebral", "start": 167, "end": 176, "id": 25}, {"text": "artery", "start": 177, "end": 183, "id": 26}, {"text": "during", "start": 184, "end": 190, "id": 27}, {"text": "systole", "start": 191, "end": 198, "id": 28}, {"text": "(", "start": 199, "end": 200, "id": 29}, {"text": "arrow", "start": 200, "end": 205, "id": 30}, {"text": ")", "start": 205, "end": 206, "id": 31}, {"text": ";", "start": 206, "end": 207, "id": 32}, {"text": "b", "start": 208, "end": 209, "id": 33}, {"text": ")", "start": 209, "end": 210, "id": 34}, {"text": "after", "start": 211, "end": 216, "id": 35}, {"text": "percutaneous", "start": 217, "end": 229, "id": 36}, {"text": "transluminal", "start": 230, "end": 242, "id": 37}, {"text": "angioplasty", "start": 243, "end": 254, "id": 38}, {"text": "showing", "start": 255, "end": 262, "id": 39}, {"text": "normal", "start": 263, "end": 269, "id": 40}, {"text": "waveforms", "start": 270, "end": 279, "id": 41}, {"text": "(", "start": 280, "end": 281, "id": 42}, {"text": "arrow", "start": 281, "end": 286, "id": 43}, {"text": ")", "start": 286, "end": 287, "id": 44}, {"text": ".", "start": 287, "end": 288, "id": 45}]}
{"pdf_hash": "a45d0f6b4f00f2c6466f846b83cf9f4e4af3657f", "fig_key": "Figure6", "fig_uri": "10-Figure6-1.png", "text": "FIGURE 6. ssDNA deposition after injection of 320 p.g ssDNA without (A) or with (B) previous injection of500 leg f3 . Indirect immunofluorescence using an SLE serum, containing antibodies to ssDNA . ssDNA is only seen along the capillary wall when preceded by injection of histone . Nuclear fluorescence is seen in all cases .", "width": 988, "height": 342, "subcaptions": {"a": [11, 12, 13, 14], "b": [16, 17, 18, 19]}, "subfigures": [{"id": "104738be-da84-45ee-9474-b34b7d9eae45", "label": "a", "points": [[11.7, 3.1], [11.7, 338.7], [481.5, 338.7], [481.5, 3.1]], "color": "yellow"}, {"id": "d9fb58f5-c1b6-4a8a-aef2-57594100a694", "label": "b", "points": [[506.5, 6.2], [506.5, 338.7], [979.4, 338.7], [979.4, 6.2]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "ssDNA", "start": 10, "end": 15, "id": 3}, {"text": "deposition", "start": 16, "end": 26, "id": 4}, {"text": "after", "start": 27, "end": 32, "id": 5}, {"text": "injection", "start": 33, "end": 42, "id": 6}, {"text": "of", "start": 43, "end": 45, "id": 7}, {"text": "320", "start": 46, "end": 49, "id": 8}, {"text": "p.g", "start": 50, "end": 53, "id": 9}, {"text": "ssDNA", "start": 54, "end": 59, "id": 10}, {"text": "without", "start": 60, "end": 67, "id": 11}, {"text": "(", "start": 68, "end": 69, "id": 12}, {"text": "A", "start": 69, "end": 70, "id": 13}, {"text": ")", "start": 70, "end": 71, "id": 14}, {"text": "or", "start": 72, "end": 74, "id": 15}, {"text": "with", "start": 75, "end": 79, "id": 16}, {"text": "(", "start": 80, "end": 81, "id": 17}, {"text": "B", "start": 81, "end": 82, "id": 18}, {"text": ")", "start": 82, "end": 83, "id": 19}, {"text": "previous", "start": 84, "end": 92, "id": 20}, {"text": "injection", "start": 93, "end": 102, "id": 21}, {"text": "of500", "start": 103, "end": 108, "id": 22}, {"text": "leg", "start": 109, "end": 112, "id": 23}, {"text": "f3", "start": 113, "end": 115, "id": 24}, {"text": ".", "start": 116, "end": 117, "id": 25}, {"text": "Indirect", "start": 118, "end": 126, "id": 26}, {"text": "immunofluorescence", "start": 127, "end": 145, "id": 27}, {"text": "using", "start": 146, "end": 151, "id": 28}, {"text": "an", "start": 152, "end": 154, "id": 29}, {"text": "SLE", "start": 155, "end": 158, "id": 30}, {"text": "serum", "start": 159, "end": 164, "id": 31}, {"text": ",", "start": 164, "end": 165, "id": 32}, {"text": "containing", "start": 166, "end": 176, "id": 33}, {"text": "antibodies", "start": 177, "end": 187, "id": 34}, {"text": "to", "start": 188, "end": 190, "id": 35}, {"text": "ssDNA", "start": 191, "end": 196, "id": 36}, {"text": ".", "start": 197, "end": 198, "id": 37}, {"text": "ssDNA", "start": 199, "end": 204, "id": 38}, {"text": "is", "start": 205, "end": 207, "id": 39}, {"text": "only", "start": 208, "end": 212, "id": 40}, {"text": "seen", "start": 213, "end": 217, "id": 41}, {"text": "along", "start": 218, "end": 223, "id": 42}, {"text": "the", "start": 224, "end": 227, "id": 43}, {"text": "capillary", "start": 228, "end": 237, "id": 44}, {"text": "wall", "start": 238, "end": 242, "id": 45}, {"text": "when", "start": 243, "end": 247, "id": 46}, {"text": "preceded", "start": 248, "end": 256, "id": 47}, {"text": "by", "start": 257, "end": 259, "id": 48}, {"text": "injection", "start": 260, "end": 269, "id": 49}, {"text": "of", "start": 270, "end": 272, "id": 50}, {"text": "histone", "start": 273, "end": 280, "id": 51}, {"text": ".", "start": 281, "end": 282, "id": 52}, {"text": "Nuclear", "start": 283, "end": 290, "id": 53}, {"text": "fluorescence", "start": 291, "end": 303, "id": 54}, {"text": "is", "start": 304, "end": 306, "id": 55}, {"text": "seen", "start": 307, "end": 311, "id": 56}, {"text": "in", "start": 312, "end": 314, "id": 57}, {"text": "all", "start": 315, "end": 318, "id": 58}, {"text": "cases", "start": 319, "end": 324, "id": 59}, {"text": ".", "start": 325, "end": 326, "id": 60}]}
{"pdf_hash": "fce157ae135b364fcd8f3b67e245daec8ce78049", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "FIGURE 7. Correlative imaging by TEM andNanoSIMS of Gd-positive pigments (areas 1 and 2) examinated by EELS (C1 and C2: higher magnification of areas 1 and 2, respectively), in the DCN of a rat from the gadodiamide group. These pigments were found, by NanoSIMS, to be rich in sulfur (A), consistent with the hypothesis that they are lipofuscin pigments. 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{"pdf_hash": "e70d80b40dbf5b7ebea908fff9f82f183edc1bb0", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Fig. 6 Analysis of abnormal compound leaves in the rel mutants. (A-C) Comparison of compound leaves among wild type (L. japonicus, Gifu ecotype) (A), rel1 (B), and rel3 (C); TL: top leaflet; LL: lateral leaflet; BL: bottom leaflet. (D-F) Comparison of leaflet initiation by SEM among wild type (D), rel1 (E) and rel3 (F); Numbers indicate the sequential initiation of leaflet primordia (The fourth leaflet primordia of wild type is shielded by the next compound leaf primordia). (G-I) Comparison of adaxial epidermis by SEM among wild type (G), rel1 (H) and rel3 (I). (J-L) Comparison of abaxial epidermis by SEM among wild type (J), rel1 (K) and rel3 (L); only the proximal parts being showed, in which arrow indicates the elongated cells. (M-O) Histological transverse sections of leaflet blade among wild type (L. japonicus, Gifu ecotype) (M), rel1 (N), and rel3 (O). 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{"pdf_hash": "7ff2472e7c52dd8dacfeccd6f5259bbb12f59c9e", "fig_key": "Figure3", "fig_uri": "9-Figure3-1.png", "text": "Figure 3 positron emission tomography imaging assessment using morphological criteria for two patients (in A man 79 years old and in B man 74 years old). PET study before treatment (a) and after the treatment (b). In (b) the lesion (arrow) exhibited a reduction of glucose uptake. PET: Positron emission tomography.", "width": 756, "height": 882, "subcaptions": null, "subfigures": [{"id": "a7acff2f-2060-435d-8890-26d5384fbe81", "label": "a", "points": [[1.2, 31.1], [1.2, 419.2], [389.3, 419.2], [389.3, 31.1]], "color": "yellow"}, {"id": "545fd42b-74e1-4d52-b041-504c14f7e7b8", "label": "a", "points": [[398.9, 28.7], [398.9, 416.8], [754.8, 416.8], [754.8, 28.7]], "color": "cyan"}, {"id": "8a461d8d-ec04-489b-a41a-215d4ea9b979", "label": "a", "points": [[3.6, 487.3], [3.6, 881.4], [359.5, 881.4], [359.5, 487.3]], "color": "magenta"}, {"id": "72c64786-6746-41d6-b01f-4b9f0b4de928", "label": "a", "points": [[370.2, 881.4], [370.2, 489.7], [752.4, 489.7], [752.4, 881.4]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "positron", "start": 9, "end": 17, "id": 2}, {"text": "emission", "start": 18, "end": 26, "id": 3}, {"text": "tomography", "start": 27, "end": 37, "id": 4}, {"text": "imaging", "start": 38, "end": 45, "id": 5}, {"text": "assessment", "start": 46, "end": 56, "id": 6}, {"text": "using", "start": 57, "end": 62, "id": 7}, {"text": "morphological", "start": 63, "end": 76, "id": 8}, {"text": "criteria", "start": 77, "end": 85, "id": 9}, {"text": "for", "start": 86, "end": 89, "id": 10}, {"text": "two", "start": 90, "end": 93, "id": 11}, {"text": "patients", "start": 94, "end": 102, "id": 12}, {"text": "(", "start": 103, "end": 104, "id": 13}, {"text": "in", "start": 104, "end": 106, "id": 14}, {"text": "A", "start": 107, "end": 108, "id": 15}, {"text": "man", "start": 109, "end": 112, "id": 16}, {"text": "79", "start": 113, "end": 115, "id": 17}, {"text": "years", "start": 116, "end": 121, "id": 18}, {"text": "old", "start": 122, "end": 125, "id": 19}, {"text": "and", "start": 126, "end": 129, "id": 20}, {"text": "in", "start": 130, "end": 132, "id": 21}, {"text": "B", "start": 133, "end": 134, "id": 22}, {"text": "man", "start": 135, "end": 138, "id": 23}, {"text": "74", "start": 139, "end": 141, "id": 24}, {"text": "years", "start": 142, "end": 147, "id": 25}, {"text": "old", "start": 148, "end": 151, "id": 26}, {"text": ")", "start": 151, "end": 152, "id": 27}, {"text": ".", "start": 152, "end": 153, "id": 28}, {"text": "PET", "start": 154, "end": 157, "id": 29}, {"text": "study", "start": 158, "end": 163, "id": 30}, {"text": "before", "start": 164, "end": 170, "id": 31}, {"text": "treatment", "start": 171, "end": 180, "id": 32}, {"text": "(", "start": 181, "end": 182, "id": 33}, {"text": "a", "start": 182, "end": 183, "id": 34}, {"text": ")", "start": 183, "end": 184, "id": 35}, {"text": "and", "start": 185, "end": 188, "id": 36}, {"text": "after", "start": 189, "end": 194, "id": 37}, {"text": "the", "start": 195, "end": 198, "id": 38}, {"text": "treatment", "start": 199, "end": 208, "id": 39}, {"text": "(", "start": 209, "end": 210, "id": 40}, {"text": "b", "start": 210, "end": 211, "id": 41}, {"text": ")", "start": 211, "end": 212, "id": 42}, {"text": ".", "start": 212, "end": 213, "id": 43}, {"text": "In", "start": 214, "end": 216, "id": 44}, {"text": "(", "start": 217, "end": 218, "id": 45}, {"text": "b", "start": 218, "end": 219, "id": 46}, {"text": ")", "start": 219, "end": 220, "id": 47}, {"text": "the", "start": 221, "end": 224, "id": 48}, {"text": "lesion", "start": 225, "end": 231, "id": 49}, {"text": "(", "start": 232, "end": 233, "id": 50}, {"text": "arrow", "start": 233, "end": 238, "id": 51}, {"text": ")", "start": 238, "end": 239, "id": 52}, {"text": "exhibited", "start": 240, "end": 249, "id": 53}, {"text": "a", "start": 250, "end": 251, "id": 54}, {"text": "reduction", "start": 252, "end": 261, "id": 55}, {"text": "of", "start": 262, "end": 264, "id": 56}, {"text": "glucose", "start": 265, "end": 272, "id": 57}, {"text": "uptake", "start": 273, "end": 279, "id": 58}, {"text": ".", "start": 279, "end": 280, "id": 59}, {"text": "PET", "start": 281, "end": 284, "id": 60}, {"text": ":", "start": 284, "end": 285, "id": 61}, {"text": "Positron", "start": 286, "end": 294, "id": 62}, {"text": "emission", "start": 295, "end": 303, "id": 63}, {"text": "tomography", "start": 304, "end": 314, "id": 64}, {"text": ".", "start": 314, "end": 315, "id": 65}]}
{"pdf_hash": "199bf67ab0ac3b7f4afcb924e47ee682057b8469", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. First screening mammogram in a 58-year-old woman who was invited for further assessment of a medial focal asymmetry in her right breast. a, b Screening mammography (right MLO and CC views). c, d Additional views (RML and CC spot view). Based on the existing images, the focal asymmetry probably correlated with a slight cranial asymmetry on the RML view. However, there were multiple further islands of breast tissue. Ultrasound did not show a correlating lesion. Since there was no architectural distortion and the slight asymmetry contained fatty inclusions, the lesion might have been misclassified as a probably benign lesion. e, f Tomosynthesis clearly demonstrates a lesion in the upper cuts of the right breast. The lesion appears quite dense and contains fine spiculations. Stereotactic vacuum-assisted breast biopsy under mammography guidance was performed, followed by breast-conserving therapy. 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{"pdf_hash": "3fab97418e36de2f5379cbf96993232a542cedae", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4. \u2014 Axial (A), coronal (B), axial oblique (C), sagittal (F) MPR views and selective VR views (D, E) illustrating a rare case of right Morgagni-Larrey hernia (MH) of the GO (white star). Epiploic veins (white arrow) clearly protrude through a 25 \u00d7 33 mm right anterior paramedian diaphragmatic hiatus (C) to expand in the right cardiophrenic space. The ligamentum teres of the falciform ligament (black arrow) is forced through the hernia.", "width": 1380, "height": 1072, "subcaptions": null, "subfigures": [{"id": "de0e391f-b5cd-4099-9ab2-974397e92d03", "label": "a", "points": [[430.6, 452], [430.6, 11.6], [5.5, 11.6], [5.5, 452]], "color": "yellow"}, {"id": "eec3fa3b-b443-4d05-84c0-9e533a0ff7e8", "label": "b", "points": [[463.3, 11.6], [463.3, 449.8], [875.4, 449.8], [875.4, 11.6]], "color": "cyan"}, {"id": "953447fa-8496-45a6-845f-fa0b8236a445", "label": "c", "points": [[914.6, 11.6], [914.6, 460.7], [1376.8, 460.7], [1376.8, 11.6]], "color": "magenta"}, {"id": "5b591edd-078d-4712-8f75-3e9c71ae1d11", "label": "d", "points": [[5.5, 460.7], [5.5, 1071.1], [417.6, 1071.1], [417.6, 460.7]], "color": "springgreen"}, {"id": "a8338b8f-f143-442a-ab3c-bb687f51577a", "label": "e", "points": [[432.8, 473.8], [432.8, 1066.8], [914.6, 1066.8], [914.6, 473.8]], "color": "tomato"}, {"id": "8e6a127a-6222-40e5-a5d4-ab0803f03c66", "label": "f", 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{"pdf_hash": "a0476f74c8ac124de930218f04e762989897bce0", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Fig. 4 Manual (expert) segmentation overlaid with automated segmentation output (white areas) of the caudate nucleus and putamen from 1.5T (upper row) and 3T (lower row) 3D T1-weighted MRI scans. Images are from a 51 year-old woman with multiple sclerosis and moderate physical disability. The total DGM volume was 28.4 ml at1.5T and 29.3 ml at 3T. For illustrative purposes, the ground truth contours are shown in both red and yellow colors. Automated segmentation was performed by the fully automated FSL-FIRST pipeline. The 3T automated output typically provided a larger and more accurate contour than 1.5T. At 1.5T, the interface between the caudate and the anterior and medial aspects of the ventricular CSF is underestimated vs. 3T. The interface between the putamen and the adjacent (lateral) white matter appears to be larger and more accurate at 3T", "width": 1342, "height": 938, "subcaptions": {"a": [24, 25, 26, 27, 28, 29], "b": [30, 31, 32, 33, 34, 35, 36]}, "subfigures": [{"id": "d8a88ac0-0b6a-46e5-b58f-8345bb9a3f02", "label": "a", "points": [[23.3, 19.1], [23.3, 460.1], [1318.7, 460.1], [1318.7, 19.1]], "color": "yellow"}, {"id": "aa58900e-a563-419f-bb73-02c7a7c6215e", "label": "b", "points": [[1318.7, 468.5], [1318.7, 911.6], [21.2, 911.6], [21.2, 468.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Manual", "start": 7, "end": 13, "id": 3}, {"text": "(", "start": 14, "end": 15, "id": 4}, {"text": "expert", "start": 15, "end": 21, "id": 5}, {"text": ")", "start": 21, "end": 22, "id": 6}, {"text": "segmentation", "start": 23, "end": 35, "id": 7}, {"text": "overlaid", "start": 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{"pdf_hash": "e1b3c0f9becead96fe621a1800f53b92f5907471", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4 Postoperative control MRI scans. a early postoperative control; b control scans after 6 months from surgery. 1,2,3 different aspects. Arrows indicate the site of the lesion", "width": 1018, "height": 724, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21]}, "subfigures": [{"id": "daae551c-1e35-41a0-ba7e-073f86fc5060", "label": "a", "points": [[2.5, 3], [2.5, 363.2], [353, 363.2], [353, 3]], "color": "yellow"}, {"id": "1f0255ab-db84-4ba8-9127-e5c4f6d4798c", "label": "a", "points": [[361.1, 4.6], [361.1, 361.6], [668.2, 361.6], [668.2, 4.6]], "color": "cyan"}, {"id": "53d5c1de-079e-41ed-9b5c-ea919c122efc", "label": "a", "points": [[679.5, 3], [679.5, 358.4], [1014, 358.4], [1014, 3]], "color": "magenta"}, {"id": "cd8a55e2-a081-4346-8f5b-80e447c6fd90", "label": "b", "points": [[5.7, 376], [5.7, 717], [343.4, 717], [343.4, 376]], "color": "springgreen"}, {"id": "cc5fc8e3-6107-4d61-8625-ffd81fd0f8a3", "label": "b", "points": [[354.7, 377.6], [354.7, 721.8], [682.7, 721.8], [682.7, 377.6]], "color": "tomato"}, {"id": "2585448b-036d-4081-b02e-7fc83113b85e", "label": "b", "points": [[692.4, 376], [692.4, 721.8], [1012.4, 721.8], [1012.4, 376]], "color": "deepskyblue"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Postoperative", "start": 7, "end": 20, "id": 3}, {"text": "control", "start": 21, "end": 28, "id": 4}, {"text": "MRI", "start": 29, "end": 32, "id": 5}, {"text": "scans", "start": 33, "end": 38, "id": 6}, {"text": ".", "start": 38, "end": 39, "id": 7}, {"text": "a", "start": 40, "end": 41, "id": 8}, {"text": "early", "start": 42, "end": 47, "id": 9}, {"text": "postoperative", "start": 48, "end": 61, "id": 10}, {"text": "control", "start": 62, "end": 69, "id": 11}, {"text": ";", "start": 69, "end": 70, "id": 12}, {"text": "b", "start": 71, "end": 72, "id": 13}, {"text": "control", "start": 73, "end": 80, "id": 14}, {"text": "scans", "start": 81, "end": 86, "id": 15}, {"text": "after", "start": 87, "end": 92, "id": 16}, {"text": "6", "start": 93, "end": 94, "id": 17}, {"text": "months", "start": 95, "end": 101, "id": 18}, {"text": "from", "start": 102, "end": 106, "id": 19}, {"text": "surgery", "start": 107, "end": 114, "id": 20}, {"text": ".", "start": 114, "end": 115, "id": 21}, {"text": "1,2,3", "start": 116, "end": 121, "id": 22}, {"text": "different", "start": 122, "end": 131, "id": 23}, {"text": "aspects", "start": 132, "end": 139, "id": 24}, {"text": ".", "start": 139, "end": 140, "id": 25}, {"text": "Arrows", "start": 141, "end": 147, "id": 26}, {"text": "indicate", "start": 148, "end": 156, "id": 27}, {"text": "the", "start": 157, "end": 160, "id": 28}, {"text": "site", "start": 161, "end": 165, "id": 29}, {"text": "of", "start": 166, "end": 168, "id": 30}, {"text": "the", "start": 169, "end": 172, "id": 31}, {"text": "lesion", "start": 173, "end": 179, "id": 32}]}
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{"pdf_hash": "b22db4c99235233bb4a87447bebe1f0593903c61", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "Fig 6. STEPS brain mask overlaid on representative slices (a, sagittal; b-c, coronal; d, transverse) of a single WT brain. Solid white lines indicate slice locations. Green markers highlight accuracy, from left, at the olfactory bulbs, paraflocculi, and cerebellum. doi:10.1371/journal.pone.0162974.g006", "width": 1418, "height": 290, "subcaptions": {"a": [11, 12, 13], "b": [15, 16, 17, 18, 19], "c": [15, 16, 17, 18, 19], "d": [21, 22, 23]}, "subfigures": [{"id": "91f6b8f7-6517-4f7d-a94e-9724657e0285", "label": "a", "points": [[7.9, 4.1], [7.9, 252.8], [462.7, 252.8], [462.7, 4.1]], "color": "yellow"}, {"id": "c2a7af1a-f0ad-4388-a6d6-d775073a957b", "label": "b", "points": [[469.4, 4.1], [469.4, 241.6], [765.2, 241.6], [765.2, 4.1]], "color": "cyan"}, {"id": "6c4c4083-c25a-47e6-8e6d-b84994b63c22", "label": "c", "points": [[774.1, 4.1], [774.1, 248.3], [1054.2, 248.3], [1054.2, 4.1]], "color": "magenta"}, {"id": "19d6be93-8e40-4076-92fc-fc3e78707027", "label": "d", "points": [[1067.6, 6.4], [1067.6, 248.3], [1412.6, 248.3], [1412.6, 6.4]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "6", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "STEPS", "start": 7, "end": 12, "id": 3}, {"text": "brain", "start": 13, "end": 18, "id": 4}, {"text": "mask", "start": 19, "end": 23, "id": 5}, {"text": "overlaid", "start": 24, "end": 32, "id": 6}, {"text": "on", "start": 33, "end": 35, "id": 7}, {"text": "representative", "start": 36, "end": 50, "id": 8}, {"text": "slices", "start": 51, "end": 57, "id": 9}, {"text": "(", "start": 58, "end": 59, "id": 10}, {"text": "a", "start": 59, "end": 60, "id": 11}, {"text": ",", "start": 60, "end": 61, "id": 12}, {"text": "sagittal", "start": 62, "end": 70, "id": 13}, {"text": ";", "start": 70, "end": 71, "id": 14}, {"text": "b", "start": 72, "end": 73, "id": 15}, {"text": "-", "start": 73, "end": 74, "id": 16}, {"text": "c", "start": 74, "end": 75, "id": 17}, {"text": ",", "start": 75, "end": 76, "id": 18}, {"text": "coronal", "start": 77, "end": 84, "id": 19}, {"text": ";", "start": 84, "end": 85, "id": 20}, {"text": "d", "start": 86, "end": 87, "id": 21}, {"text": ",", "start": 87, "end": 88, "id": 22}, {"text": "transverse", "start": 89, "end": 99, "id": 23}, {"text": ")", "start": 99, "end": 100, "id": 24}, {"text": "of", "start": 101, "end": 103, "id": 25}, {"text": "a", "start": 104, "end": 105, "id": 26}, {"text": "single", "start": 106, "end": 112, "id": 27}, {"text": "WT", "start": 113, "end": 115, "id": 28}, {"text": "brain", "start": 116, "end": 121, "id": 29}, {"text": ".", "start": 121, "end": 122, "id": 30}, {"text": "Solid", "start": 123, "end": 128, "id": 31}, {"text": "white", "start": 129, "end": 134, "id": 32}, {"text": "lines", "start": 135, "end": 140, "id": 33}, {"text": "indicate", "start": 141, "end": 149, "id": 34}, {"text": "slice", "start": 150, "end": 155, "id": 35}, {"text": "locations", "start": 156, "end": 165, "id": 36}, {"text": ".", "start": 165, "end": 166, "id": 37}, {"text": "Green", "start": 167, "end": 172, "id": 38}, {"text": "markers", "start": 173, "end": 180, "id": 39}, {"text": "highlight", "start": 181, "end": 190, "id": 40}, {"text": "accuracy", "start": 191, "end": 199, "id": 41}, {"text": ",", "start": 199, "end": 200, "id": 42}, {"text": "from", "start": 201, "end": 205, "id": 43}, {"text": "left", "start": 206, "end": 210, "id": 44}, {"text": ",", "start": 210, "end": 211, "id": 45}, {"text": "at", "start": 212, "end": 214, "id": 46}, {"text": "the", "start": 215, "end": 218, "id": 47}, {"text": "olfactory", "start": 219, "end": 228, "id": 48}, {"text": "bulbs", "start": 229, "end": 234, "id": 49}, {"text": ",", "start": 234, "end": 235, "id": 50}, {"text": "paraflocculi", "start": 236, "end": 248, "id": 51}, {"text": ",", "start": 248, "end": 249, "id": 52}, {"text": "and", "start": 250, "end": 253, "id": 53}, {"text": "cerebellum", "start": 254, "end": 264, "id": 54}, {"text": ".", "start": 264, "end": 265, "id": 55}, {"text": "doi:10.1371", "start": 266, "end": 277, "id": 56}, {"text": "/", "start": 277, "end": 278, "id": 57}, {"text": "journal.pone.0162974.g006", "start": 278, "end": 303, "id": 58}]}
{"pdf_hash": "1a96bba58dfbe67806ae5788ac6d5a18deacd67b", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Pre-procedure (A), post-procedure (B) and follow-up angiographic images (C) coupled to corresponding OCT images. OCT images were captured in corresponding segments through main vessel (D and G) and SB (E, F, H, and I) (i.e., same OCT segment is depicted between post-procedure, and follow-up) by means of a software synchronization tool. Pre-procedure angiographic image shows a true bifurcation lesion. After the procedure, the OCT image demonstrates dissection of main vessel, and SB ostium shows compromise from the dissected flap of the main vessel (D). At follow-up, the lumen area of the main vessel (G and H) and SB ostium (H and I) increases further due to the drug effect. The dissections as seen on OCT at the SB ostium have healed (G). The arrows and asterisks represent SB ostium. 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{"pdf_hash": "846ff0bbdb139a7e2d398691e02a2e571f552f32", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5. Two-dimensional commensurate layer struc ture, (a) Molecular resolution imaging of saturated L-methionine monolayer (/ = 0.11 nA, U = -250 mV), (b) Periodicity of the biomolecular self-assembly. The molecular ordering follows the atomic lattice of the Ag(111 ) substrate. Vectors (eu ?j) define a basis for the unit cell of the Ag(111) atomic lattice (/ = 0.30 nA, U = 200 mV). The unit cell of the monolayer structure is marked in white.", "width": 906, "height": 472, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46]}, "subfigures": [{"id": "066a03c5-7669-4c03-a7ca-ca74a6bf5a41", "label": "a", "points": [[2.2, 6.9], [2.2, 467.8], [461.6, 467.8], [461.6, 6.9]], "color": "yellow"}, {"id": "ac05fa88-128e-4de3-a1c1-632a6060ab04", "label": "b", "points": [[470.2, 5.5], [470.2, 467.8], [898.1, 467.8], [898.1, 5.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Two", "start": 8, "end": 11, "id": 4}, {"text": "-", "start": 11, "end": 12, "id": 5}, {"text": "dimensional", "start": 12, "end": 23, "id": 6}, {"text": "commensurate", "start": 24, "end": 36, "id": 7}, {"text": 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{"pdf_hash": "dac37f883e1e5c94ae5e270fedee6ce2006ba794", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Fig 5. Endoscopic series demonstrating the release of fibrous bands around the sciatic nerve of the right hip with the patient in the lateral decubitus position. (A) With a shaver positioned through the proximal trochanteric portal and once the sciatic nerve (SC) is located, release of the fibrotic bands (FB) around the nerve is performed. (B) The vasa nervorum increase on the sciatic nerve (SC) after release of the fibrous band. The shaver is positioned through the proximal trochanteric portal and is used to probe the nerve; a 30 arthroscope is positioned through the distal trochanteric portal.", "width": 1062, "height": 386, "subcaptions": {"a": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "b": [65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113]}, "subfigures": [{"id": "af1106c1-3f18-446d-b2db-a33dfb1cea20", "label": "a", "points": [[-0.8, 3.1], [-0.8, 383.9], [512.6, 383.9], [512.6, 3.1]], "color": "yellow"}, {"id": "b79eb8ef-81b8-424a-a811-ea238eef8a2a", "label": "b", "points": [[521, 1.4], [521, 378.9], [1049.4, 378.9], [1049.4, 1.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "5", "start": 4, "end": 5, 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{"pdf_hash": "0f7199e6ec6b391234b4370148dcfb15866738c6", "fig_key": "Figure5", "fig_uri": "3-Figure5-1.png", "text": "Figure 5) Computed tomography images of the chest showing multiple large air-filled cysts on the right side associated with mediastinal shift. A Coronal view. B Transverse view", "width": 670, "height": 1034, "subcaptions": {"a": [25, 26, 27], "b": [29, 30, 31]}, "subfigures": [{"id": "c6816b75-5bd1-45ea-b34c-5219b3ad22df", "label": "a", "points": [[4.2, 1.1], [4.2, 501.7], [667.9, 501.7], [667.9, 1.1]], "color": "yellow"}, {"id": "39fe1b32-252c-490a-90b7-80beba6becdc", "label": "b", "points": [[3.2, 1005.5], [3.2, 505.9], [667.9, 505.9], [667.9, 1005.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ")", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomography", "start": 19, "end": 29, "id": 4}, {"text": "images", "start": 30, "end": 36, "id": 5}, {"text": "of", "start": 37, "end": 39, "id": 6}, {"text": "the", "start": 40, "end": 43, "id": 7}, {"text": "chest", "start": 44, "end": 49, "id": 8}, {"text": "showing", "start": 50, "end": 57, "id": 9}, {"text": "multiple", "start": 58, "end": 66, "id": 10}, {"text": "large", "start": 67, "end": 72, "id": 11}, {"text": "air", "start": 73, "end": 76, "id": 12}, {"text": "-", "start": 76, "end": 77, "id": 13}, {"text": "filled", "start": 77, "end": 83, "id": 14}, {"text": "cysts", "start": 84, "end": 89, "id": 15}, {"text": "on", "start": 90, "end": 92, "id": 16}, {"text": "the", "start": 93, "end": 96, "id": 17}, {"text": "right", "start": 97, "end": 102, "id": 18}, {"text": "side", "start": 103, "end": 107, "id": 19}, {"text": "associated", "start": 108, "end": 118, "id": 20}, {"text": "with", "start": 119, "end": 123, "id": 21}, {"text": "mediastinal", "start": 124, "end": 135, "id": 22}, {"text": "shift", "start": 136, "end": 141, "id": 23}, {"text": ".", "start": 141, "end": 142, "id": 24}, {"text": "A", "start": 143, "end": 144, "id": 25}, {"text": "Coronal", "start": 145, "end": 152, "id": 26}, {"text": "view", "start": 153, "end": 157, "id": 27}, {"text": ".", "start": 157, "end": 158, "id": 28}, {"text": "B", "start": 159, "end": 160, "id": 29}, {"text": "Transverse", "start": 161, "end": 171, "id": 30}, {"text": "view", "start": 172, "end": 176, "id": 31}]}
{"pdf_hash": "c680ae062222c0e90a4257da437d7adb99fc40ca", "fig_key": "Figure6", "fig_uri": "12-Figure6-1.png", "text": "Fig. 6. Cone beam computed tomography scan (small field of view: 4 3 4 cm) of the anterior maxilla of a 66-year-old female patient after referral by her treating dentist 1 year following insertion of a dental implant in region 21. The patient reported persisting neuropathic pain in the anterior mandible toward the nose. (A) Sagittal view showing penetration of the dental implant in region 21 into the nasopalatine canal. (B) Coronal view of the restored implant in region 21. Slight osteolysis is visible at the apical region of tooth 11. 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{"pdf_hash": "9e14690b975cd24d8e033f8b00371acc0d7c957f", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. Vertebral collapse with cement destruction in a 75-year-old man. (A) Immediately postoperative radiograph of L1. (B) Postoperative 5.5 years follow-up radiograph showed a mild vertebral collapse with increased focal kyphotic angle.", "width": 638, "height": 490, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "7b7f0fb5-24de-47b2-b1c0-70f8648432a1", "label": "a", "points": [[1.6, 2.9], [1.6, 454.4], [317, 454.4], [317, 2.9]], "color": "yellow"}, {"id": "4434ea01-2ef5-44f9-8024-a37c9ecbf691", "label": "b", "points": [[334.1, 0.8], [334.1, 454.4], [635.5, 454.4], [635.5, 0.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Vertebral", "start": 8, "end": 17, "id": 4}, {"text": "collapse", "start": 18, "end": 26, "id": 5}, {"text": "with", "start": 27, "end": 31, "id": 6}, {"text": "cement", "start": 32, "end": 38, "id": 7}, {"text": "destruction", "start": 39, "end": 50, "id": 8}, {"text": "in", "start": 51, "end": 53, "id": 9}, {"text": "a", "start": 54, "end": 55, "id": 10}, {"text": "75-year", "start": 56, "end": 63, "id": 11}, {"text": "-", "start": 63, "end": 64, "id": 12}, {"text": "old", "start": 64, "end": 67, "id": 13}, {"text": "man", "start": 68, "end": 71, "id": 14}, {"text": ".", "start": 71, "end": 72, "id": 15}, {"text": "(", "start": 73, "end": 74, "id": 16}, {"text": "A", "start": 74, "end": 75, "id": 17}, {"text": ")", "start": 75, "end": 76, "id": 18}, {"text": "Immediately", "start": 77, "end": 88, "id": 19}, {"text": "postoperative", "start": 89, "end": 102, "id": 20}, {"text": "radiograph", "start": 103, "end": 113, "id": 21}, {"text": "of", "start": 114, "end": 116, "id": 22}, {"text": "L1", "start": 117, "end": 119, "id": 23}, {"text": ".", "start": 119, "end": 120, "id": 24}, {"text": "(", "start": 121, "end": 122, "id": 25}, {"text": "B", "start": 122, "end": 123, "id": 26}, {"text": ")", "start": 123, "end": 124, "id": 27}, {"text": "Postoperative", "start": 125, "end": 138, "id": 28}, {"text": "5.5", "start": 139, "end": 142, "id": 29}, {"text": "years", "start": 143, "end": 148, "id": 30}, {"text": "follow", "start": 149, "end": 155, "id": 31}, {"text": "-", "start": 155, "end": 156, "id": 32}, {"text": "up", "start": 156, "end": 158, "id": 33}, {"text": "radiograph", "start": 159, "end": 169, "id": 34}, {"text": "showed", "start": 170, "end": 176, "id": 35}, {"text": "a", "start": 177, "end": 178, "id": 36}, {"text": "mild", "start": 179, "end": 183, "id": 37}, {"text": "vertebral", "start": 184, "end": 193, "id": 38}, {"text": "collapse", "start": 194, "end": 202, "id": 39}, {"text": "with", "start": 203, "end": 207, "id": 40}, {"text": "increased", "start": 208, "end": 217, "id": 41}, {"text": "focal", "start": 218, "end": 223, "id": 42}, {"text": "kyphotic", "start": 224, "end": 232, "id": 43}, {"text": "angle", "start": 233, "end": 238, "id": 44}, {"text": ".", "start": 238, "end": 239, "id": 45}]}
{"pdf_hash": "effb014893b74ea4a3f1cf28003d5587249aa55b", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 Postoperative changes and anatomy of the locus coeruleus. Left plane: 12-day postoperative sagittal gadolinium-enhanced T1-weighted MRI illustrating the resection cavity with a small haemorrhage in the tectal plate and local oedema. 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{"pdf_hash": "a8d77906837b906b36b881c1ea6b8344be593087", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4. A: skin ulceration and oozing with fluid. B: Ultrasound examination showed a nearly solid lesion with blood flow signal in the solid component.", "width": 1340, "height": 492, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "c27724a5-e867-4285-a2e5-83a10135486b", "label": "a", "points": [[41.4, 29.3], [41.4, 461.1], [663.7, 461.1], [663.7, 29.3]], "color": "yellow"}, {"id": "3305095b-d5f8-4ecd-8a9d-399db11eba55", "label": "b", "points": [[678.5, 31.4], [678.5, 461.1], [1300.8, 461.1], [1300.8, 31.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ":", "start": 11, "end": 12, "id": 4}, {"text": "skin", "start": 13, "end": 17, "id": 5}, {"text": "ulceration", "start": 18, "end": 28, "id": 6}, {"text": "and", "start": 29, "end": 32, "id": 7}, {"text": "oozing", "start": 33, "end": 39, "id": 8}, {"text": "with", "start": 40, "end": 44, "id": 9}, {"text": "fluid", "start": 45, "end": 50, "id": 10}, {"text": ".", "start": 50, "end": 51, "id": 11}, {"text": "B", "start": 52, "end": 53, "id": 12}, {"text": ":", "start": 53, "end": 54, "id": 13}, {"text": "Ultrasound", "start": 55, "end": 65, "id": 14}, {"text": "examination", "start": 66, "end": 77, "id": 15}, {"text": "showed", "start": 78, "end": 84, "id": 16}, {"text": "a", "start": 85, "end": 86, "id": 17}, {"text": "nearly", "start": 87, "end": 93, "id": 18}, {"text": "solid", "start": 94, "end": 99, "id": 19}, {"text": "lesion", "start": 100, "end": 106, "id": 20}, {"text": "with", "start": 107, "end": 111, "id": 21}, {"text": "blood", "start": 112, "end": 117, "id": 22}, {"text": "flow", "start": 118, "end": 122, "id": 23}, {"text": "signal", "start": 123, "end": 129, "id": 24}, {"text": "in", "start": 130, "end": 132, "id": 25}, {"text": "the", "start": 133, "end": 136, "id": 26}, {"text": "solid", "start": 137, "end": 142, "id": 27}, {"text": "component", "start": 143, "end": 152, "id": 28}, {"text": ".", "start": 152, "end": 153, "id": 29}]}
{"pdf_hash": "cf7b59d9cf858a46cf9821bce1277320cc093b04", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Fig. 6 Water absorption process of seeds. Five kinds of seeds, broad bean, corn, morning-glory, wheat and rice were placed in water and every 2 h they were taken out from the water and neutron imaging was performed. Upper left picture of five seeds. Bar 5 mm. The distribution of water after absorption was not uniform in all the seeds. 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{"pdf_hash": "a90550e8b19136eecc7e79131e44546f19a4e616", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2 Example of no-reflow on a myocardial contrast echocardiogram performed immediately after restoration of TIMI 3 patency by primary angioplasty in a patient with anterior acute myocardial infarction. Left panel: apical four-chamber view; right panel: apical twochamber view. Heterogeneous contrast enhancement (in left panel) and endocardial contrast defect (in right panel) are indicated by arrows.", "width": 784, "height": 584, "subcaptions": null, "subfigures": [{"id": "13c17993-f35d-45c2-9b19-3d8dfa20703d", "label": "a", "points": [[4.4, 1], [4.4, 563.3], [385.8, 563.3], [385.8, 1]], "color": "yellow"}, {"id": "25f5dded-fc89-491b-85f5-d6e2a9deafbc", "label": "b", "points": [[398.2, 2.3], [398.2, 554.6], [782.2, 554.6], [782.2, 2.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Example", "start": 9, "end": 16, "id": 2}, {"text": "of", "start": 17, "end": 19, "id": 3}, {"text": "no", "start": 20, "end": 22, "id": 4}, {"text": "-", "start": 22, "end": 23, "id": 5}, {"text": "reflow", "start": 23, "end": 29, "id": 6}, {"text": "on", "start": 30, "end": 32, "id": 7}, {"text": "a", "start": 33, "end": 34, "id": 8}, {"text": "myocardial", "start": 35, "end": 45, "id": 9}, {"text": "contrast", "start": 46, "end": 54, "id": 10}, {"text": "echocardiogram", "start": 55, "end": 69, "id": 11}, {"text": "performed", "start": 70, "end": 79, "id": 12}, {"text": "immediately", "start": 80, "end": 91, "id": 13}, {"text": "after", "start": 92, "end": 97, "id": 14}, {"text": "restoration", "start": 98, "end": 109, "id": 15}, {"text": "of", "start": 110, "end": 112, "id": 16}, {"text": "TIMI", "start": 113, "end": 117, "id": 17}, {"text": "3", "start": 118, "end": 119, "id": 18}, {"text": "patency", "start": 120, "end": 127, "id": 19}, {"text": "by", "start": 128, "end": 130, "id": 20}, {"text": "primary", "start": 131, "end": 138, "id": 21}, {"text": "angioplasty", "start": 139, "end": 150, "id": 22}, {"text": "in", "start": 151, "end": 153, "id": 23}, {"text": "a", "start": 154, "end": 155, "id": 24}, {"text": "patient", "start": 156, "end": 163, "id": 25}, {"text": "with", "start": 164, "end": 168, "id": 26}, {"text": "anterior", "start": 169, "end": 177, "id": 27}, {"text": "acute", "start": 178, "end": 183, "id": 28}, {"text": "myocardial", "start": 184, "end": 194, "id": 29}, {"text": "infarction", "start": 195, "end": 205, "id": 30}, {"text": ".", "start": 205, "end": 206, "id": 31}, {"text": "Left", "start": 207, "end": 211, "id": 32}, {"text": "panel", "start": 212, "end": 217, "id": 33}, {"text": ":", "start": 217, "end": 218, "id": 34}, {"text": "apical", "start": 219, "end": 225, "id": 35}, {"text": "four", "start": 226, "end": 230, "id": 36}, {"text": "-", "start": 230, "end": 231, "id": 37}, {"text": "chamber", "start": 231, "end": 238, "id": 38}, {"text": "view", "start": 239, "end": 243, "id": 39}, {"text": ";", "start": 243, "end": 244, "id": 40}, {"text": "right", "start": 245, "end": 250, "id": 41}, {"text": "panel", "start": 251, "end": 256, "id": 42}, {"text": ":", "start": 256, "end": 257, "id": 43}, {"text": "apical", "start": 258, "end": 264, "id": 44}, {"text": "twochamber", "start": 265, "end": 275, "id": 45}, {"text": "view", "start": 276, "end": 280, "id": 46}, {"text": ".", "start": 280, "end": 281, "id": 47}, {"text": "Heterogeneous", "start": 282, "end": 295, "id": 48}, {"text": "contrast", "start": 296, "end": 304, "id": 49}, {"text": "enhancement", "start": 305, "end": 316, "id": 50}, {"text": "(", "start": 317, "end": 318, "id": 51}, {"text": "in", "start": 318, "end": 320, "id": 52}, {"text": "left", "start": 321, "end": 325, "id": 53}, {"text": "panel", "start": 326, "end": 331, "id": 54}, {"text": ")", "start": 331, "end": 332, "id": 55}, {"text": "and", "start": 333, "end": 336, "id": 56}, {"text": "endocardial", "start": 337, "end": 348, "id": 57}, {"text": "contrast", "start": 349, "end": 357, "id": 58}, {"text": "defect", "start": 358, "end": 364, "id": 59}, {"text": "(", "start": 365, "end": 366, "id": 60}, {"text": "in", "start": 366, "end": 368, "id": 61}, {"text": "right", "start": 369, "end": 374, "id": 62}, {"text": "panel", "start": 375, "end": 380, "id": 63}, {"text": ")", "start": 380, "end": 381, "id": 64}, {"text": "are", "start": 382, "end": 385, "id": 65}, {"text": "indicated", "start": 386, "end": 395, "id": 66}, {"text": "by", "start": 396, "end": 398, "id": 67}, {"text": "arrows", "start": 399, "end": 405, "id": 68}, {"text": ".", "start": 405, "end": 406, "id": 69}]}
{"pdf_hash": "22d7095df963fc729dbe3498c877d4e95c02d293", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 Case 5: (a) axial T2-weighted image revealing a hyperintense mass in the medial head of the gastrocnemius. (b) Postgadolinium T1-weighted coronal image showing peripheral enhancement of the capsule with no enhancement in the centre.", "width": 652, "height": 946, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "37039400-e6ed-4e67-8551-5f6b7a0a272c", "label": "a", "points": [[3.1, 0], [3.1, 453.2], [645.8, 453.2], [645.8, 0]], "color": "yellow"}, {"id": "956f70ec-99b9-4607-94f5-c07eab78aef1", "label": "b", "points": [[1, 455.3], [1, 942.5], [342, 942.5], [342, 455.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "Case", "start": 9, "end": 13, "id": 2}, {"text": "5", "start": 14, "end": 15, "id": 3}, {"text": ":", "start": 15, "end": 16, "id": 4}, {"text": "(", "start": 17, "end": 18, "id": 5}, {"text": "a", "start": 18, "end": 19, "id": 6}, {"text": ")", "start": 19, "end": 20, "id": 7}, {"text": "axial", "start": 21, "end": 26, "id": 8}, {"text": "T2-weighted", "start": 27, "end": 38, "id": 9}, {"text": "image", "start": 39, "end": 44, "id": 10}, {"text": "revealing", "start": 45, "end": 54, "id": 11}, {"text": "a", "start": 55, "end": 56, "id": 12}, {"text": "hyperintense", "start": 57, "end": 69, "id": 13}, {"text": "mass", "start": 70, "end": 74, "id": 14}, {"text": "in", "start": 75, "end": 77, "id": 15}, {"text": "the", "start": 78, "end": 81, "id": 16}, {"text": "medial", "start": 82, "end": 88, "id": 17}, {"text": "head", "start": 89, "end": 93, "id": 18}, {"text": "of", "start": 94, "end": 96, "id": 19}, {"text": "the", "start": 97, "end": 100, "id": 20}, {"text": "gastrocnemius", "start": 101, "end": 114, "id": 21}, {"text": ".", "start": 114, "end": 115, "id": 22}, {"text": "(", "start": 116, "end": 117, "id": 23}, {"text": "b", "start": 117, "end": 118, "id": 24}, {"text": ")", "start": 118, "end": 119, "id": 25}, {"text": "Postgadolinium", "start": 120, "end": 134, "id": 26}, {"text": "T1-weighted", "start": 135, "end": 146, "id": 27}, {"text": "coronal", "start": 147, "end": 154, "id": 28}, {"text": "image", "start": 155, "end": 160, "id": 29}, {"text": "showing", "start": 161, "end": 168, "id": 30}, {"text": "peripheral", "start": 169, "end": 179, "id": 31}, {"text": "enhancement", "start": 180, "end": 191, "id": 32}, {"text": "of", "start": 192, "end": 194, "id": 33}, {"text": "the", "start": 195, "end": 198, "id": 34}, {"text": "capsule", "start": 199, "end": 206, "id": 35}, {"text": "with", "start": 207, "end": 211, "id": 36}, {"text": "no", "start": 212, "end": 214, "id": 37}, {"text": "enhancement", "start": 215, "end": 226, "id": 38}, {"text": "in", "start": 227, "end": 229, "id": 39}, {"text": "the", "start": 230, "end": 233, "id": 40}, {"text": "centre", "start": 234, "end": 240, "id": 41}, {"text": ".", "start": 240, "end": 241, "id": 42}]}
{"pdf_hash": "f02646031fa981c4990108a87460980b8baacbb8", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 Complications after surgeries in the single PET group: One button on the coracoid side slipped out from the original place in 2 cases in single PLE group (a); Rockwood type II AC joint dislocation occurred in four cases: two of them were due to EndoButton separation (b), and the other two were due to button eroding into the superior clavicle cortex (c)", "width": 1006, "height": 286, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74]}, "subfigures": [{"id": "2b95baae-af47-4e58-a93f-b8a0d124a091", "label": "a", "points": [[37.4, 20.4], [37.4, 250.8], [344.1, 250.8], [344.1, 20.4]], "color": 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{"pdf_hash": "2720fb7a848850776891c129bfb12a51be472379", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4. Brain and facial motor nucleus morphology. Transverse sections of E18.5 WT (left) and Nmnat2 blad/blad (BLAD) (right) forebrains (A), and higher magnification views of the corpus callosum (B). Up is dorsal in (B). (C) Transverse sections of E18.5 WT (left) and BLAD (right) brainstem showing the loss of facial motoneurons (see text for quantitation). Dotted line denotes the boundary of the motor nucleus. 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{"pdf_hash": "07498440d640affd181de84a56a3a24d2ece2c44", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Sebaceous gland atrophy in K5-R2b-null mice. By 3 months of age, epidermal whole-mount peroxidase staining (sebaceous glands appear brown) combined with Mayer's hemalum counterstain revealed that sebaceous glands in the tail of K5-R2b-null mice were virtually absent (compare (A) with (B)). This absence was confirmed by scanning through H&E-stained serial transverse sections of tail skin, looking for sebocytes (arrows in (C) and (D); asterisks indicate transversely sectioned hair shafts). (C) and (D) represent sections showing the largest proportion of sebaceous tissue encountered in serial transverse sections from tails of wild-type and K5-R2b-null mice, respectively. Scale bar, 200 mm.", "width": 644, "height": 932, "subcaptions": null, "subfigures": [{"id": "faacedea-ce3f-49d7-9548-46d3a734607a", "label": "a", "points": [[318.4, 436.5], [318.4, 35.6], [3.1, 35.6], [3.1, 436.5]], "color": "yellow"}, {"id": "d0de622b-0448-476c-a158-6af7042f0de5", "label": "b", "points": [[327.6, 33.6], [327.6, 429.3], [640.9, 429.3], [640.9, 33.6]], "color": "cyan"}, {"id": "fb129685-8e70-4cce-a60a-5d39de43dc61", "label": "c", "points": [[2, 443.6], [2, 897.3], [314.4, 897.3], [314.4, 443.6]], "color": "magenta"}, {"id": "6ed33fd0-6469-4176-b3ff-cfdc303ade3f", "label": "d", "points": [[324.5, 897.3], [324.5, 443.6], [642, 443.6], [642, 897.3]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Sebaceous", "start": 9, "end": 18, "id": 2}, {"text": "gland", "start": 19, "end": 24, "id": 3}, {"text": "atrophy", "start": 25, "end": 32, "id": 4}, {"text": "in", "start": 33, 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"encountered", "start": 584, "end": 595, "id": 116}, {"text": "in", "start": 596, "end": 598, "id": 117}, {"text": "serial", "start": 599, "end": 605, "id": 118}, {"text": "transverse", "start": 606, "end": 616, "id": 119}, {"text": "sections", "start": 617, "end": 625, "id": 120}, {"text": "from", "start": 626, "end": 630, "id": 121}, {"text": "tails", "start": 631, "end": 636, "id": 122}, {"text": "of", "start": 637, "end": 639, "id": 123}, {"text": "wild", "start": 640, "end": 644, "id": 124}, {"text": "-", "start": 644, "end": 645, "id": 125}, {"text": "type", "start": 645, "end": 649, "id": 126}, {"text": "and", "start": 650, "end": 653, "id": 127}, {"text": "K5-R2b", "start": 654, "end": 660, "id": 128}, {"text": "-", "start": 660, "end": 661, "id": 129}, {"text": "null", "start": 661, "end": 665, "id": 130}, {"text": "mice", "start": 666, "end": 670, "id": 131}, {"text": ",", "start": 670, "end": 671, "id": 132}, {"text": "respectively", "start": 672, "end": 684, "id": 133}, 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{"pdf_hash": "cf1b0fb1d22ff8f6f570c096f6b2476865d7cf57", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Soft X-ray tomographic reconstruction of phenotypically distinct C. albicans cells. A representative orthoslice from each tomographic reconstruction is shown for a yeast-like (A), germ-tube (C) and hyphal (E) cell. Volume rendered views of the same cells are shown in (B, D, and F) respectively showing selected organelles that have been segmented and color-coded for identification. Blue, nucleus; orange, nucleolus; gray, mitochondria; yellow, vacuole; green, lipid bodies. (Scale bar for A\u2013D, 0.5 m, for E and F, 2.0 m.)", "width": 684, "height": 796, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 46, 47, 103, 104, 105, 106, 107, 108, 109, 110, 111], "b": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 103, 104, 105, 106, 107, 108, 109, 110, 111], "c": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 35, 36, 37, 38, 39, 40, 46, 47, 103, 104, 105, 106, 107, 108, 109, 110, 111], "d": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 103, 104, 105, 106, 107, 108, 109, 110, 111], "e": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 42, 43, 44, 45, 46, 47, 113, 114, 115, 116, 117, 118, 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{"pdf_hash": "d0198e20a4af7b61b5b557c7c05c85d2eb8dcf42", "fig_key": "Figure4", "fig_uri": "9-Figure4-1.png", "text": "Figure 4. Six week-old grower rabbit euthanized by blunt force trauma. (A) Survey radiograph demonstrating fractured cranium (arrow); (B) Minimal subdural dorsal hemorrhage covers less than 25% of the brain surface (gross score of 1/4); (C) Photomicrograph of cerebellum (demonstrating mild subdural hemorrhage (*) (histologic score of 2/4) and no parenchymal hemorrhage (histologic score of 0/4). No subdural or parenchymal hemorrhage were noted in the midbrain. 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{"pdf_hash": "5be604fd7cdb7cf650fbfb9164460c84fd9ae0fa", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. A 65-year-old male with a 6-mm tubulovillous adenoma in the sigmoid colon. A. Optical colonoscopy shows a sessile polyp (arrowhead) in the sigmoid colon. B. 3D supine endoluminal view shows the corresponding polyp (arrowhead) in a well-distended segment of the sigmoid colon. 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{"pdf_hash": "566c0dba68d0aa638cea2386818ee4c2de9009e0", "fig_key": "Figure9", "fig_uri": "4-Figure9-1.png", "text": "Figure 9 MRI demonstrating resolution of phase encoding pulsation artifact after treatment. Left panel: T1 axial baseline image demonstrating the marked phase encoding pulsation artifact due to turbulent flow in the giant aneurysm. Right panel: the image obtained at delayed follow-up shows near complete resolution of the phase encoding pulsation artifact following endovascular treatment.", "width": 894, "height": 454, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "cddcf5a1-3605-4460-80b9-83abbee553f3", "label": "a", "points": [[27.2, 2.6], [27.2, 433.4], [455.2, 433.4], [455.2, 2.6]], "color": "yellow"}, {"id": "9b771c41-c2f5-4c27-9ee4-cf9f9e3bb9ba", "label": "b", "points": [[459.4, 2.6], [459.4, 424.9], [893, 424.9], [893, 2.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "9", "start": 7, "end": 8, "id": 1}, {"text": "MRI", "start": 9, "end": 12, "id": 2}, {"text": "demonstrating", "start": 13, "end": 26, "id": 3}, {"text": "resolution", "start": 27, "end": 37, "id": 4}, {"text": "of", "start": 38, "end": 40, "id": 5}, {"text": "phase", "start": 41, "end": 46, "id": 6}, {"text": "encoding", "start": 47, "end": 55, "id": 7}, {"text": "pulsation", "start": 56, "end": 65, "id": 8}, {"text": "artifact", "start": 66, "end": 74, "id": 9}, {"text": "after", "start": 75, "end": 80, "id": 10}, {"text": "treatment", "start": 81, "end": 90, "id": 11}, {"text": ".", "start": 90, "end": 91, "id": 12}, {"text": "Left", "start": 92, "end": 96, "id": 13}, {"text": "panel", "start": 97, "end": 102, "id": 14}, {"text": ":", "start": 102, "end": 103, "id": 15}, {"text": "T1", "start": 104, "end": 106, "id": 16}, {"text": "axial", "start": 107, "end": 112, "id": 17}, {"text": "baseline", "start": 113, "end": 121, "id": 18}, {"text": "image", "start": 122, "end": 127, "id": 19}, {"text": "demonstrating", "start": 128, "end": 141, "id": 20}, {"text": "the", "start": 142, "end": 145, "id": 21}, {"text": "marked", "start": 146, "end": 152, "id": 22}, {"text": "phase", "start": 153, "end": 158, "id": 23}, {"text": "encoding", "start": 159, "end": 167, "id": 24}, {"text": "pulsation", "start": 168, "end": 177, "id": 25}, {"text": "artifact", "start": 178, "end": 186, "id": 26}, {"text": "due", "start": 187, "end": 190, "id": 27}, {"text": "to", "start": 191, "end": 193, "id": 28}, {"text": "turbulent", "start": 194, "end": 203, "id": 29}, {"text": "flow", "start": 204, "end": 208, "id": 30}, {"text": "in", "start": 209, "end": 211, "id": 31}, {"text": "the", "start": 212, "end": 215, "id": 32}, {"text": "giant", "start": 216, "end": 221, "id": 33}, {"text": "aneurysm", "start": 222, "end": 230, "id": 34}, {"text": ".", "start": 230, "end": 231, "id": 35}, {"text": "Right", "start": 232, "end": 237, "id": 36}, {"text": "panel", "start": 238, "end": 243, "id": 37}, {"text": ":", "start": 243, "end": 244, "id": 38}, {"text": "the", "start": 245, "end": 248, "id": 39}, {"text": "image", "start": 249, "end": 254, "id": 40}, {"text": "obtained", "start": 255, "end": 263, "id": 41}, {"text": "at", "start": 264, "end": 266, "id": 42}, {"text": "delayed", "start": 267, "end": 274, "id": 43}, {"text": "follow", "start": 275, "end": 281, "id": 44}, {"text": "-", "start": 281, "end": 282, "id": 45}, {"text": "up", "start": 282, "end": 284, "id": 46}, {"text": "shows", "start": 285, "end": 290, "id": 47}, {"text": "near", "start": 291, "end": 295, "id": 48}, {"text": "complete", "start": 296, "end": 304, "id": 49}, {"text": "resolution", "start": 305, "end": 315, "id": 50}, {"text": "of", "start": 316, "end": 318, "id": 51}, {"text": "the", "start": 319, "end": 322, "id": 52}, {"text": "phase", "start": 323, "end": 328, "id": 53}, {"text": "encoding", "start": 329, "end": 337, "id": 54}, {"text": "pulsation", "start": 338, "end": 347, "id": 55}, {"text": "artifact", "start": 348, "end": 356, "id": 56}, {"text": "following", "start": 357, "end": 366, "id": 57}, {"text": "endovascular", "start": 367, "end": 379, "id": 58}, {"text": "treatment", "start": 380, "end": 389, "id": 59}, {"text": ".", "start": 389, "end": 390, "id": 60}]}
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{"pdf_hash": "37fa018f7c285151c8cf76e6eb5f3141302ece7d", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. Extension of the KASH Domain of UNC-83 Blocks Nuclear Migration (A-C) GFP expression in comma-stage embryos with the version of UNC-83 indicated. Anterior is left; dorsal is up. Scale bar, 10 mm. (A) UNC-83::GFP::KASH. (B) unc-119, which serves as the wild-type UNC-83 (no GFP) control. (C) UNC-83::GFP::KASH+A. (D) Quantification of nuclear migration defects by counting the average number of hyp7 nuclei in the dorsal cords of larval stage (L)1 animals. 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{"pdf_hash": "9fd47a4998c870bbc4412e0a47c87ac128614097", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4 Patient 2, left frontal GBM, contrast-enhanced CT imaging (a\u2013 c) and SPECT/CT (d\u2013f). a Initial CT scan before stereotactic biopsy and catheter placement. CT scan at b 6 weeks and at c 10 weeks after radiopeptide treatment. Besides the intratumoural changes, please note the increasing perifocal oedema. 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{"pdf_hash": "3c3496271f1dba2f9270de6ba7d329b59c378a4a", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4 Three-dimensional reconstruction of the nasal wall in the lower facial region at 24 weeks of gestation (CRL, 210 mm). a Frontal view of the maxillary sinus and nasal cavity. The locations of the cross-sectional axial slices that were taken through the area of interest are indicated (a1). Three-dimensional frontal view of the maxillary sinus and nasal cavity. The uncinate process of the ethmoid bone is located near the nasal side of the maxilla (a2). b Horizontal view of the maxillary sinus and nasal cavity. The locations of the cross-sectional axial slices taken through the area of interest are indicated (b1). Three-dimensional horizontal view of the maxillary sinus and nasal cavity (b2). 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{"pdf_hash": "75a34c5f4a80841337bffa4afd4a153d9fdf6e3b", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1A\u2013C A plain AP radiograph of the proximal tibia shows the three proximal fixation methods: (A) two standard mediolateral locking screws, (B) two mediolateral ASLS (angular stable locking system) screws, and (C) one ASLS screw combined with two oblique cancellous bone screws.", "width": 1248, "height": 426, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 29, 30, 31], "c": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57]}, "subfigures": [{"id": "397f852a-83f5-46d1-be2f-3db0465cfd55", "label": "a", "points": [[39.8, 8.5], [39.8, 387.1], [434.1, 387.1], [434.1, 8.5]], "color": "yellow"}, {"id": "69a8ea57-c00f-4eac-97da-7916560e8766", "label": "b", "points": [[451.8, 2.6], [451.8, 389.1], [838.3, 389.1], [838.3, 2.6]], "color": "cyan"}, {"id": "ad295d33-1965-41b4-a318-6477d06a8c7a", "label": "c", "points": [[844.2, 12.5], [844.2, 387.1], [1209, 387.1], [1209, 12.5]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1A", "start": 5, "end": 7, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "C", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 10, "end": 11, "id": 5}, {"text": "plain", "start": 12, "end": 17, "id": 6}, {"text": "AP", "start": 18, "end": 20, "id": 7}, {"text": "radiograph", "start": 21, "end": 31, "id": 8}, {"text": "of", "start": 32, "end": 34, "id": 9}, {"text": "the", "start": 35, "end": 38, "id": 10}, {"text": "proximal", "start": 39, "end": 47, "id": 11}, {"text": "tibia", "start": 48, "end": 53, "id": 12}, {"text": "shows", "start": 54, "end": 59, "id": 13}, {"text": "the", "start": 60, "end": 63, "id": 14}, {"text": "three", "start": 64, "end": 69, "id": 15}, {"text": "proximal", "start": 70, "end": 78, "id": 16}, {"text": "fixation", "start": 79, "end": 87, "id": 17}, {"text": "methods", "start": 88, "end": 95, "id": 18}, {"text": ":", "start": 95, "end": 96, "id": 19}, {"text": "(", "start": 97, "end": 98, "id": 20}, {"text": "A", "start": 98, "end": 99, "id": 21}, {"text": ")", "start": 99, "end": 100, "id": 22}, {"text": "two", "start": 101, "end": 104, "id": 23}, {"text": "standard", "start": 105, "end": 113, "id": 24}, {"text": "mediolateral", "start": 114, "end": 126, "id": 25}, {"text": "locking", "start": 127, "end": 134, "id": 26}, {"text": "screws", "start": 135, "end": 141, "id": 27}, {"text": ",", "start": 141, "end": 142, "id": 28}, {"text": "(", "start": 143, "end": 144, "id": 29}, {"text": "B", "start": 144, "end": 145, "id": 30}, {"text": ")", "start": 145, "end": 146, "id": 31}, {"text": "two", "start": 147, "end": 150, "id": 32}, {"text": "mediolateral", "start": 151, "end": 163, "id": 33}, {"text": "ASLS", "start": 164, "end": 168, "id": 34}, {"text": "(", "start": 169, "end": 170, "id": 35}, {"text": "angular", "start": 170, "end": 177, "id": 36}, {"text": "stable", "start": 178, "end": 184, "id": 37}, {"text": "locking", "start": 185, "end": 192, "id": 38}, {"text": "system", "start": 193, "end": 199, "id": 39}, {"text": ")", "start": 199, "end": 200, "id": 40}, {"text": "screws", "start": 201, "end": 207, "id": 41}, {"text": ",", "start": 207, "end": 208, "id": 42}, {"text": "and", "start": 209, "end": 212, "id": 43}, {"text": "(", "start": 213, "end": 214, "id": 44}, {"text": "C", "start": 214, "end": 215, "id": 45}, {"text": ")", "start": 215, "end": 216, "id": 46}, {"text": "one", "start": 217, "end": 220, "id": 47}, {"text": "ASLS", "start": 221, "end": 225, "id": 48}, {"text": "screw", "start": 226, "end": 231, "id": 49}, {"text": "combined", "start": 232, "end": 240, "id": 50}, {"text": "with", "start": 241, "end": 245, "id": 51}, {"text": "two", "start": 246, "end": 249, "id": 52}, {"text": "oblique", "start": 250, "end": 257, "id": 53}, {"text": "cancellous", "start": 258, "end": 268, "id": 54}, {"text": "bone", "start": 269, "end": 273, "id": 55}, {"text": "screws", "start": 274, "end": 280, "id": 56}, {"text": ".", "start": 280, "end": 281, "id": 57}]}
{"pdf_hash": "a65ab92aa8625a7c2d43ca69b72cb66cb86fd174", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. endoscopic ultrasound image shows a 3.3 cm \u00d7 2.5 cm mixed hypoechoic\u2013isoechoic mass lesion in the submucosal region of distal thoracic esophagus, which was in close proximity to the left atrium (A). Fine needle aspiration of the mass (white arrow) (B). Fna smear showed a cellular smear with clusters of atypical cells with nuclear polymorphism, scant cytoplasm, coarse chromatin, and small nucleoli suggestive of squamous cell carcinoma (C).", "width": 1378, "height": 380, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54], "c": [55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87]}, "subfigures": [{"id": "15448171-8bbf-4065-b143-a4fc89554651", "label": "a", "points": [[64.3, 30.1], [64.3, 378.4], [447.4, 378.4], [447.4, 30.1]], "color": "yellow"}, {"id": "6f3e8cbd-7632-49e0-bb1b-79a2253a4bd6", "label": "b", "points": [[514.9, 30.1], [514.9, 374.1], [843.6, 374.1], [843.6, 30.1]], "color": "cyan"}, {"id": "35341acc-ec3e-4716-9713-12a08754f6e6", "label": "c", "points": [[906.8, 34.5], 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{"pdf_hash": "63d4b854ca518bc2ddd2cf7d749d3f62ee0b7feb", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4. 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{"pdf_hash": "796e60cc9f1abf18a3ba3e35db4e73d258d28780", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. MR imaging of the right proximal leg. Axial T1-weighted (A) and T2-weighted (B) MR images depict a well-circumscribed, elliptical mass (arrows) with a central, fusiform, fluid-filled cavity in the deep subcutaneous layer of the right proximal leg. Note the wavy, low-signal-intensity structures (arrowhead) in the central cavity, representing the gauze fibers. 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{"pdf_hash": "950615b01d15ae585eb8ac2387893c2d49af529f", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4 Desmoid left triceps in a 60-year-old male with recurrence after surgery. a Initial MRI demonstrating infiltrating enhancing desmoid adjacent to the left humerus. b MRI 1 year later after surgical resection with negative margins demonstrated a larger tumor recurrence. c Axial CT demonstrates several Perc 24 Endocare cryoablation probes angled throughout the lesion. d One-year follow-up demonstrated residual", "width": 1250, "height": 1056, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 30, 31], "c": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61], "d": [64, 65, 66, 67, 68, 69, 70, 62, 63]}, "subfigures": [{"id": "91014835-db19-4c99-abd8-14aff04d3c8f", "label": "a", "points": [[40.1, 21.5], [40.1, 528.9], [336.2, 528.9], [336.2, 21.5]], "color": "yellow"}, 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{"pdf_hash": "1b2055d354a96c932e08627dcebbb8c49ed0b661", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 a Axial T2 TSE of a 64-year-old male showing the volumetric contour of a TZ prostate tumor for extraction of mp-MRI parameters. b Axial post gadolinium dynamic contrastenhanced image. c Axial (b) = 2000 mm/s 2 . d ADC Bmap4", "width": 1016, "height": 1022, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [32, 33, 34, 35, 36, 37, 30, 31], "c": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "d": [50, 51, 52]}, "subfigures": [{"id": "bf0d9f86-62a4-416f-bc71-6e26f182556b", "label": "a", "points": [[24.3, 35.8], [24.3, 469.2], [493, 469.2], [493, 35.8]], "color": "yellow"}, {"id": "75f068db-2d46-4d2d-8f2e-09efd609dddd", "label": "b", "points": [[525.1, 39.1], [525.1, 464.4], [993.8, 464.4], [993.8, 39.1]], "color": "cyan"}, {"id": "51d79039-37bf-45e3-b343-b728190a8ced", "label": "c", "points": [[21.1, 514.2], [21.1, 934.7], [489.8, 934.7], [489.8, 514.2]], "color": "magenta"}, {"id": "5368c7a7-9102-4d00-ab01-5e5622525ace", "label": "d", "points": [[528.3, 510.9], [528.3, 941.1], [993.8, 941.1], [993.8, 510.9]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Axial", "start": 9, "end": 14, "id": 4}, {"text": "T2", "start": 15, "end": 17, "id": 5}, {"text": "TSE", "start": 18, "end": 21, "id": 6}, {"text": "of", "start": 22, "end": 24, "id": 7}, {"text": "a", "start": 25, "end": 26, "id": 8}, {"text": "64-year", "start": 27, "end": 34, "id": 9}, {"text": "-", "start": 34, "end": 35, "id": 10}, {"text": "old", "start": 35, "end": 38, "id": 11}, {"text": "male", "start": 39, "end": 43, "id": 12}, {"text": "showing", "start": 44, "end": 51, "id": 13}, {"text": "the", "start": 52, "end": 55, "id": 14}, {"text": "volumetric", "start": 56, "end": 66, "id": 15}, {"text": "contour", "start": 67, "end": 74, "id": 16}, {"text": "of", "start": 75, "end": 77, "id": 17}, {"text": "a", "start": 78, "end": 79, "id": 18}, {"text": "TZ", "start": 80, "end": 82, "id": 19}, {"text": "prostate", "start": 83, "end": 91, "id": 20}, {"text": "tumor", "start": 92, "end": 97, "id": 21}, {"text": "for", "start": 98, "end": 101, "id": 22}, {"text": "extraction", "start": 102, "end": 112, "id": 23}, {"text": "of", "start": 113, "end": 115, "id": 24}, {"text": "mp", "start": 116, "end": 118, "id": 25}, {"text": "-", "start": 118, "end": 119, "id": 26}, {"text": "MRI", "start": 119, "end": 122, "id": 27}, {"text": "parameters", "start": 123, "end": 133, "id": 28}, {"text": ".", "start": 133, "end": 134, "id": 29}, {"text": "b", "start": 135, "end": 136, "id": 30}, {"text": "Axial", "start": 137, "end": 142, "id": 31}, {"text": "post", "start": 143, "end": 147, "id": 32}, {"text": "gadolinium", "start": 148, "end": 158, "id": 33}, {"text": "dynamic", "start": 159, "end": 166, "id": 34}, {"text": "contrastenhanced", "start": 167, "end": 183, "id": 35}, {"text": "image", "start": 184, "end": 189, "id": 36}, {"text": ".", "start": 189, "end": 190, "id": 37}, {"text": "c", "start": 191, "end": 192, "id": 38}, {"text": "Axial", "start": 193, "end": 198, "id": 39}, {"text": "(", "start": 199, "end": 200, "id": 40}, {"text": "b", "start": 200, "end": 201, "id": 41}, {"text": ")", "start": 201, "end": 202, "id": 42}, {"text": "=", "start": 203, "end": 204, "id": 43}, {"text": "2000", "start": 205, "end": 209, "id": 44}, {"text": "mm", "start": 210, "end": 212, "id": 45}, {"text": "/", "start": 212, "end": 213, "id": 46}, {"text": "s", "start": 213, "end": 214, "id": 47}, {"text": "2", "start": 215, "end": 216, "id": 48}, {"text": ".", "start": 217, "end": 218, "id": 49}, {"text": "d", "start": 219, "end": 220, "id": 50}, {"text": "ADC", "start": 221, "end": 224, "id": 51}, {"text": "Bmap4", "start": 225, "end": 230, "id": 52}]}
{"pdf_hash": "750297be4b000a53c43283367b5d4c2945950348", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. A 41-year-old man with malignant melanoma and widespread metastases including the brain. WB MRI imaging shows multiple lesions outside the field of view of CT thorax and abdomen. (a) A maximum intensity projection (MIP) image of DWI shows the disease distribution in a valuable overview of the entire body; (b) coronal T2-STIR and (c) coronal T1W sequence, respectively, show further anatomical details of metastatic lesions.", "width": 540, "height": 644, "subcaptions": {"a": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "b": [64, 65, 72, 76, 77, 78, 79, 80, 81, 82, 83, 61, 62, 63], "c": [67, 68, 69, 70, 71, 72, 76, 77, 78, 79, 80, 81, 82, 83]}, "subfigures": [{"id": "e2491e3e-d6d6-4ac7-964c-2728a5a81b3d", "label": "a", "points": [[2.5, 4], [2.5, 617], [166.5, 617], [166.5, 4]], "color": "yellow"}, {"id": "bebabf83-eaa2-463d-82bd-cee980f3d3e0", "label": "b", "points": [[171.5, 5], [171.5, 612], [347.5, 612], [347.5, 5]], "color": "cyan"}, {"id": "40a97fe7-25b3-44bc-b2ee-30aee3ff9e1b", "label": "c", "points": [[352.5, 2], [352.5, 613], [509.5, 613], [509.5, 2]], "color": "magenta"}], "tokens": [{"text": 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{"pdf_hash": "44a2952dc85a2ed98746d4b0eb3815d7b757bcd1", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Patient presented with swelling and ptosis of the right upper eyelid. (a) Head CT of the orbit revealed abnormal high density area (yellow circle); (b) MRI revealed the presence of an infiltration of the right intraorbital diffuse mass which regressed and decreased in size one month after treatment was initiated.", "width": 1342, "height": 564, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60]}, "subfigures": [{"id": "59773f50-5fb7-46ea-a58d-7161fd275e38", "label": "a", "points": [[27.9, 17.7], [27.9, 539.2], [587.6, 539.2], [587.6, 17.7]], "color": "yellow"}, {"id": "22fd2526-0ec9-4e95-b93d-e8b6aa9e9c3d", "label": "b", "points": [[693.6, 26.1], [693.6, 528.6], [1317, 528.6], [1317, 26.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Patient", "start": 9, "end": 16, "id": 2}, {"text": "presented", "start": 17, "end": 26, "id": 3}, {"text": "with", "start": 27, "end": 31, "id": 4}, {"text": "swelling", "start": 32, "end": 40, "id": 5}, {"text": "and", "start": 41, "end": 44, "id": 6}, {"text": "ptosis", "start": 45, "end": 51, "id": 7}, {"text": "of", "start": 52, "end": 54, "id": 8}, {"text": "the", "start": 55, "end": 58, "id": 9}, {"text": "right", "start": 59, "end": 64, "id": 10}, {"text": "upper", "start": 65, "end": 70, "id": 11}, {"text": "eyelid", "start": 71, "end": 77, "id": 12}, {"text": ".", "start": 77, "end": 78, "id": 13}, {"text": "(", "start": 79, "end": 80, "id": 14}, {"text": "a", "start": 80, "end": 81, "id": 15}, {"text": ")", "start": 81, "end": 82, "id": 16}, {"text": "Head", "start": 83, "end": 87, "id": 17}, {"text": "CT", "start": 88, "end": 90, "id": 18}, {"text": "of", "start": 91, "end": 93, "id": 19}, {"text": "the", "start": 94, "end": 97, "id": 20}, {"text": "orbit", "start": 98, "end": 103, "id": 21}, {"text": "revealed", "start": 104, "end": 112, "id": 22}, {"text": "abnormal", "start": 113, "end": 121, "id": 23}, {"text": "high", "start": 122, "end": 126, "id": 24}, {"text": "density", "start": 127, "end": 134, "id": 25}, {"text": "area", "start": 135, "end": 139, "id": 26}, {"text": "(", "start": 140, "end": 141, "id": 27}, {"text": "yellow", "start": 141, "end": 147, "id": 28}, {"text": "circle", "start": 148, "end": 154, "id": 29}, {"text": ")", "start": 154, "end": 155, "id": 30}, {"text": ";", "start": 155, "end": 156, "id": 31}, {"text": "(", "start": 157, "end": 158, "id": 32}, {"text": "b", "start": 158, "end": 159, "id": 33}, {"text": ")", "start": 159, "end": 160, "id": 34}, {"text": "MRI", "start": 161, "end": 164, "id": 35}, {"text": "revealed", "start": 165, "end": 173, "id": 36}, {"text": "the", "start": 174, "end": 177, "id": 37}, {"text": "presence", "start": 178, "end": 186, "id": 38}, {"text": "of", "start": 187, "end": 189, "id": 39}, {"text": "an", "start": 190, "end": 192, "id": 40}, {"text": "infiltration", "start": 193, "end": 205, "id": 41}, {"text": "of", "start": 206, "end": 208, "id": 42}, {"text": "the", "start": 209, "end": 212, "id": 43}, {"text": "right", "start": 213, "end": 218, "id": 44}, {"text": "intraorbital", "start": 219, "end": 231, "id": 45}, {"text": "diffuse", "start": 232, "end": 239, "id": 46}, {"text": "mass", "start": 240, "end": 244, "id": 47}, {"text": "which", "start": 245, "end": 250, "id": 48}, {"text": "regressed", "start": 251, "end": 260, "id": 49}, {"text": "and", "start": 261, "end": 264, "id": 50}, {"text": "decreased", "start": 265, "end": 274, "id": 51}, {"text": "in", "start": 275, "end": 277, "id": 52}, {"text": "size", "start": 278, "end": 282, "id": 53}, {"text": "one", "start": 283, "end": 286, "id": 54}, {"text": "month", "start": 287, "end": 292, "id": 55}, {"text": "after", "start": 293, "end": 298, "id": 56}, {"text": "treatment", "start": 299, "end": 308, "id": 57}, {"text": "was", "start": 309, "end": 312, "id": 58}, {"text": "initiated", "start": 313, "end": 322, "id": 59}, {"text": ".", "start": 322, "end": 323, "id": 60}]}
{"pdf_hash": "ed24238d5f1c6815d61931d235642822ec874a6f", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2: Right cerebellar hemorrhagic lesion from Case 2. (a) Computed tomography of the head at presentation showed a large hemorrhage of the right cerebellar hemisphere with displacement of the fourth ventricle. (b) Magnetic resonance imaging brain, T2 sequence showed perilesional edema and some associated vessels. (c) Right vertebral artery injection DynaCT, coronal view, showed an arteriovenous malformation with feeders from the right anterior and posterior cerebellar arteries. 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{"pdf_hash": "bcb054619b16367d296bfe03c048193929d565ef", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "FIGURE 3: Images from a 62-year-old male with carotid plaque ulceration (arrow) detected by both conventional multicontrast protocol and SNAP. Multicontrast protocol: a: T 1 W; b: T 2 W; c: MP-RAGE; d: TOF; e: TOF MRA. SNAP: f: CR; g: MRA; h: Ref; i: Ref2; j: CR (curved multiplanar reconstruction); k: sagittal MRA. 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{"pdf_hash": "9cbb1c8318929f7b1a64d8e70c65ff41c4130ec4", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Macroscopic appearance of the brain. (a). Before fixation, the cerebrum shows general moderate atrophy with widening of the sulci, particularly in the frontal lobe. The cerebellum also shows general atrophy. (b). A coronal section of the left cerebral hemisphere shows mild thinning of the neocortex with mild dilatation of the lateral ventricles. The striatum, white matter, and hippocampus are relatively preserved from the atrophy. Numerous small petechiae are recognized in the hypothalamus. (c). A lowpower field image of the coronal section at the level of the mamillary body shows numerous petechiae in the mamillary body, hypothalamus, and column of the fornix (d). Low-power field image of the horizontal section of the pons also shows several petechiae in the tegmentum. 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{"pdf_hash": "9b3a13bc73a9972d79497bb3c8aa15cd230ff837", "fig_key": "Figure11", "fig_uri": "10-Figure11-1.png", "text": "Fig. 11. Immunofluorescent localization of tubulin and KIFC1 in mature E. modestus sperm. (A) DAPI nuclear staining. (B) Tubulin staining. Tubulin (green staining; arrows) localizes specifically to the center of the acrosome. (C) KIFC1 staining. KIFC1 (red staining; arrows) localizes throughout the whole acrosome including the AFS-derived spike (D) Phase contrast microscopy. This figure shows the general morphological appearance of the E. modestus mature sperm. (E) Merged immunofluorescent images. Tubulin (green staining; arrows) and KIFC1 (red staining; arrows) localization is shown. Nucleus (blue staining). (F) Diagram. This diagram shows the distribution of tubulin (green) and KIFC1 (red dots) in the E. modestus mature sperm. 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{"pdf_hash": "05e83e7fc10e29ce3827eae4aec66311d721d959", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. Hemophagous region of the cat paraplacenta. Very intense erythrophagocytosis is exhibited by cytotrophoblast cells (T). (A) Maternal erythrocytes (arrow) are seen internalized at the trophoblast cytoplasm. (B) Asterisk shows reactive cytotrophoblast cells to cathepsin D (immunohistochemistry, monoclonal anti-human cathepsin D, Dako, USA). 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{"pdf_hash": "f4d96481aa0861a2c8ffe91dda6f3bb83b1d95d0", "fig_key": "Figure6", "fig_uri": "10-Figure6-1.png", "text": "Figure 6. A 70-year-old male with previous partial nephrectomy for renal cell carcinoma: (a) post-contrast CT coronal reconstruction imaging revealed a locally recurrent tumour (star), which was subsequently treated by cryoablation. (b) In the 3-month follow-up MRI, the tumour was hypointense on T2 weighted imaging with a dense hypointense rim (thin arrows). (c) After contrast administration (from left to right: coronal pre-contrast phase, coronal corticomedullary phase, coronal nephrographic phase and axial delay phase), the medial posterior part of the ablated tumour exhibited a gradual nodular enhancement (thick arrows). 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{"pdf_hash": "99a0d3bb9375f37e5734c9a39694a2f1f40ceaf8", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1: (a) Right renal angiomyolipoma (gross specimen postexcision). (b) High-resolution computed tomography chest images of Case 1 showing multiple variable sized cysts uniformly scattered in both lungs. (c) Computed tomography abdomen showing bilateral renal angiomyolipomas with fat densities, tortuous vessels, and pseudoaneurysm (white arrow). There is also the presence of perinephric hematoma (black arrow). (d) High-resolution computed tomography image of Case 2 showing bilateral lung cysts d c", "width": 674, "height": 516, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14], "b": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "c": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75], "d": [76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91]}, "subfigures": [{"id": "d5810396-85d8-4962-aa14-db8acf75d1b3", "label": "a", "points": [[19.7, 3], [19.7, 238.3], [323.2, 238.3], [323.2, 3]], "color": "yellow"}, {"id": "9654ff1a-ce8c-4e98-86e5-c476ddc2df3a", "label": "b", "points": [[330.6, 4.1], [330.6, 239.4], [658.6, 239.4], [658.6, 4.1]], "color": "cyan"}, {"id": "a5bbbdbf-a7de-4130-807b-9f481b6406f2", "label": "c", "points": [[16.5, 242.6], [16.5, 486.4], [323.2, 486.4], [323.2, 242.6]], "color": "magenta"}, {"id": 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{"pdf_hash": "a610e539cba5ea713109c356665235461be8451e", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. (A) Chest radiograph: symmetric pattern of diffuse fine micronodules in both lungs. (BeC) HRCT images: diffuse symmetric pattern of microlithiasis, consisting of both discrete nodules and areas of ground glass attenuation of the lung parenchyma.", "width": 1014, "height": 572, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "c": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "6e0a9a7b-2d0e-42af-b36a-f2de306bd587", "label": "a", "points": [[23.3, 1.3], [23.3, 449.8], [593.5, 449.8], [593.5, 1.3]], "color": "yellow"}, {"id": "535b51fb-a06a-4821-afb9-566ecc7c33bf", "label": "b", "points": [[619.2, -0.3], [619.2, 217.6], [981.2, 217.6], [981.2, -0.3]], "color": "cyan"}, {"id": "b7eb9805-cbe9-4ad8-bd50-88857db0309f", "label": "c", "points": [[614.4, 228.8], [614.4, 537.9], [979.6, 537.9], [979.6, 228.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Chest", "start": 12, "end": 17, "id": 7}, {"text": "radiograph", "start": 18, "end": 28, "id": 8}, {"text": ":", "start": 28, "end": 29, "id": 9}, {"text": "symmetric", "start": 30, "end": 39, "id": 10}, {"text": "pattern", "start": 40, "end": 47, "id": 11}, {"text": "of", "start": 48, "end": 50, "id": 12}, {"text": "diffuse", "start": 51, "end": 58, "id": 13}, {"text": "fine", "start": 59, "end": 63, "id": 14}, {"text": "micronodules", "start": 64, "end": 76, "id": 15}, {"text": "in", "start": 77, "end": 79, "id": 16}, {"text": "both", "start": 80, "end": 84, "id": 17}, {"text": "lungs", "start": 85, "end": 90, "id": 18}, {"text": ".", "start": 90, "end": 91, "id": 19}, {"text": "(", "start": 92, "end": 93, "id": 20}, {"text": "BeC", "start": 93, "end": 96, "id": 21}, {"text": ")", "start": 96, "end": 97, "id": 22}, {"text": "HRCT", "start": 98, "end": 102, "id": 23}, {"text": "images", "start": 103, "end": 109, "id": 24}, {"text": ":", "start": 109, "end": 110, "id": 25}, {"text": "diffuse", "start": 111, "end": 118, "id": 26}, {"text": "symmetric", "start": 119, "end": 128, "id": 27}, {"text": "pattern", "start": 129, "end": 136, "id": 28}, {"text": "of", "start": 137, "end": 139, "id": 29}, {"text": "microlithiasis", "start": 140, "end": 154, "id": 30}, {"text": ",", "start": 154, "end": 155, "id": 31}, {"text": "consisting", "start": 156, "end": 166, "id": 32}, {"text": "of", "start": 167, "end": 169, "id": 33}, {"text": "both", "start": 170, "end": 174, "id": 34}, {"text": "discrete", "start": 175, "end": 183, "id": 35}, {"text": "nodules", "start": 184, "end": 191, "id": 36}, {"text": "and", "start": 192, "end": 195, "id": 37}, {"text": "areas", "start": 196, "end": 201, "id": 38}, {"text": "of", "start": 202, "end": 204, "id": 39}, {"text": "ground", "start": 205, "end": 211, "id": 40}, {"text": "glass", "start": 212, "end": 217, "id": 41}, {"text": "attenuation", "start": 218, "end": 229, "id": 42}, {"text": "of", "start": 230, "end": 232, "id": 43}, {"text": "the", "start": 233, "end": 236, "id": 44}, {"text": "lung", "start": 237, "end": 241, "id": 45}, {"text": "parenchyma", "start": 242, "end": 252, "id": 46}, {"text": ".", "start": 252, "end": 253, "id": 47}]}
{"pdf_hash": "1305871a393b909a16999367779b498dfda73b46", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 (A) Abdominal CT scan showing peritoneal/omental thickening, (B) enlarged prostate gland and (C) ascites.", "width": 860, "height": 868, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14], "b": [15, 16, 17, 18, 19, 20], "c": [22, 23, 24, 25, 26]}, "subfigures": [{"id": "407cc10c-673b-4849-b6f4-124695c9647b", "label": "a", "points": [[0.7, 36.5], [0.7, 418.2], [404.2, 418.2], [404.2, 36.5]], "color": "yellow"}, {"id": "143ba7b0-90ea-4c7e-b5cc-2d281b64dac0", "label": "b", "points": [[424.6, 35.1], [424.6, 416.8], [858, 416.8], [858, 35.1]], "color": "cyan"}, {"id": "e09040dd-934c-4f76-83f1-577faef90f14", "label": "c", "points": [[-0.6, 480.7], [-0.6, 833.9], [397.4, 833.9], [397.4, 480.7]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "(", "start": 7, "end": 8, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": ")", "start": 9, "end": 10, "id": 5}, {"text": "Abdominal", "start": 11, "end": 20, "id": 6}, {"text": "CT", "start": 21, "end": 23, "id": 7}, {"text": "scan", "start": 24, "end": 28, "id": 8}, {"text": "showing", "start": 29, "end": 36, "id": 9}, {"text": "peritoneal", "start": 37, "end": 47, "id": 10}, {"text": "/", "start": 47, "end": 48, "id": 11}, {"text": "omental", "start": 48, "end": 55, "id": 12}, {"text": "thickening", "start": 56, "end": 66, "id": 13}, {"text": ",", "start": 66, "end": 67, "id": 14}, {"text": "(", "start": 68, "end": 69, "id": 15}, {"text": "B", "start": 69, "end": 70, "id": 16}, {"text": ")", "start": 70, "end": 71, "id": 17}, {"text": "enlarged", "start": 72, "end": 80, "id": 18}, {"text": "prostate", "start": 81, "end": 89, "id": 19}, {"text": "gland", "start": 90, "end": 95, "id": 20}, {"text": "and", "start": 96, "end": 99, "id": 21}, {"text": "(", "start": 100, "end": 101, "id": 22}, {"text": "C", "start": 101, "end": 102, "id": 23}, {"text": ")", "start": 102, "end": 103, "id": 24}, {"text": "ascites", "start": 104, "end": 111, "id": 25}, {"text": ".", "start": 111, "end": 112, "id": 26}]}
{"pdf_hash": "ea1d018f2e5ef48868f5cbbe10d5c63cc4eda2d0", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIGURE 1: a) Axial non-contrasted abdominal CT scan, showing a collection adjacent to the ascending colon signaled by the white arrow; notice the surrounding stranded fat. b) Axial image of the same CT scan, with the red arrow showing an enlarged appendix with surrounding inflamed fat.", "width": 1088, "height": 816, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "fe2ca8f7-6a84-4dd0-9994-90d3cd90b87f", "label": "a", "points": [[3.4, 0], [3.4, 464.1], [546.6, 464.1], [546.6, 0]], "color": "yellow"}, {"id": "fbf0f911-d660-4f4d-a511-92323e961136", "label": "b", "points": [[558.6, 465.8], [558.6, 6.9], [1084.6, 6.9], [1084.6, 465.8]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Axial", "start": 13, "end": 18, "id": 5}, {"text": "non", "start": 19, "end": 22, "id": 6}, {"text": "-", "start": 22, "end": 23, "id": 7}, {"text": "contrasted", "start": 23, "end": 33, "id": 8}, {"text": "abdominal", "start": 34, "end": 43, "id": 9}, {"text": "CT", "start": 44, "end": 46, "id": 10}, {"text": "scan", "start": 47, "end": 51, "id": 11}, {"text": ",", "start": 51, "end": 52, "id": 12}, {"text": "showing", "start": 53, "end": 60, "id": 13}, {"text": "a", "start": 61, "end": 62, "id": 14}, {"text": "collection", "start": 63, "end": 73, "id": 15}, {"text": "adjacent", "start": 74, "end": 82, "id": 16}, {"text": "to", "start": 83, "end": 85, "id": 17}, {"text": "the", "start": 86, "end": 89, "id": 18}, {"text": "ascending", "start": 90, "end": 99, "id": 19}, {"text": "colon", "start": 100, "end": 105, "id": 20}, {"text": "signaled", "start": 106, "end": 114, "id": 21}, {"text": "by", "start": 115, "end": 117, "id": 22}, {"text": "the", "start": 118, "end": 121, "id": 23}, {"text": "white", "start": 122, "end": 127, "id": 24}, {"text": "arrow", "start": 128, "end": 133, "id": 25}, {"text": ";", "start": 133, "end": 134, "id": 26}, {"text": "notice", "start": 135, "end": 141, "id": 27}, {"text": "the", "start": 142, "end": 145, "id": 28}, {"text": "surrounding", "start": 146, "end": 157, "id": 29}, {"text": "stranded", "start": 158, "end": 166, "id": 30}, {"text": "fat", "start": 167, "end": 170, "id": 31}, {"text": ".", "start": 170, "end": 171, "id": 32}, {"text": "b", "start": 172, "end": 173, "id": 33}, {"text": ")", "start": 173, "end": 174, "id": 34}, {"text": "Axial", "start": 175, "end": 180, "id": 35}, {"text": "image", "start": 181, "end": 186, "id": 36}, {"text": "of", "start": 187, "end": 189, "id": 37}, {"text": "the", "start": 190, "end": 193, "id": 38}, {"text": "same", "start": 194, "end": 198, "id": 39}, {"text": "CT", "start": 199, "end": 201, "id": 40}, {"text": "scan", "start": 202, "end": 206, "id": 41}, {"text": ",", "start": 206, "end": 207, "id": 42}, {"text": "with", "start": 208, "end": 212, "id": 43}, {"text": "the", "start": 213, "end": 216, "id": 44}, {"text": "red", "start": 217, "end": 220, "id": 45}, {"text": "arrow", "start": 221, "end": 226, "id": 46}, {"text": "showing", "start": 227, "end": 234, "id": 47}, {"text": "an", "start": 235, "end": 237, "id": 48}, {"text": "enlarged", "start": 238, "end": 246, "id": 49}, {"text": "appendix", "start": 247, "end": 255, "id": 50}, {"text": "with", "start": 256, "end": 260, "id": 51}, {"text": "surrounding", "start": 261, "end": 272, "id": 52}, {"text": "inflamed", "start": 273, "end": 281, "id": 53}, {"text": "fat", "start": 282, "end": 285, "id": 54}, {"text": ".", "start": 285, "end": 286, "id": 55}]}
{"pdf_hash": "bd21e07e93e6e594e80cd2e3e15f8903872da6c2", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "FIGURE 1 T1-weighted MRI shows an isosignal tumor from the falx cerebri to the left. A: sagittal view; B: coronal view.", "width": 410, "height": 814, "subcaptions": {"a": [16, 17, 18, 19], "b": [24, 21, 22, 23]}, "subfigures": [{"id": "b624c1cc-be4f-44cd-8142-88d732ce3ca2", "label": "a", "points": [[1.5, 1], [1.5, 391], [407.5, 391], [407.5, 1]], "color": "yellow"}, {"id": "6382e693-47b8-4736-8db3-957d15b1547e", "label": "b", "points": [[1.5, 408], [1.5, 812], [406.5, 812], [406.5, 408]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "T1-weighted", "start": 9, "end": 20, "id": 2}, {"text": "MRI", "start": 21, "end": 24, "id": 3}, {"text": "shows", "start": 25, "end": 30, "id": 4}, {"text": "an", "start": 31, "end": 33, "id": 5}, {"text": "isosignal", "start": 34, "end": 43, "id": 6}, {"text": "tumor", "start": 44, "end": 49, "id": 7}, {"text": "from", "start": 50, "end": 54, "id": 8}, {"text": "the", "start": 55, "end": 58, "id": 9}, {"text": "falx", "start": 59, "end": 63, "id": 10}, {"text": "cerebri", "start": 64, "end": 71, "id": 11}, {"text": "to", "start": 72, "end": 74, "id": 12}, {"text": "the", "start": 75, "end": 78, "id": 13}, {"text": "left", "start": 79, "end": 83, "id": 14}, {"text": ".", "start": 83, "end": 84, "id": 15}, {"text": "A", "start": 85, "end": 86, "id": 16}, {"text": ":", "start": 86, "end": 87, "id": 17}, {"text": "sagittal", "start": 88, "end": 96, "id": 18}, {"text": "view", "start": 97, "end": 101, "id": 19}, {"text": ";", "start": 101, "end": 102, "id": 20}, {"text": "B", "start": 103, "end": 104, "id": 21}, {"text": ":", "start": 104, "end": 105, "id": 22}, {"text": "coronal", "start": 106, "end": 113, "id": 23}, {"text": "view", "start": 114, "end": 118, "id": 24}, {"text": ".", "start": 118, "end": 119, "id": 25}]}
{"pdf_hash": "c27e1426272c1f4b1b5510afea6aba83ff6f2731", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Computed tomography on admission. A) Pancreatic sweling and necrosis near the pancreas. B) Cystic structure (arrow) near the galbladder and antrum.", "width": 1066, "height": 380, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "a6bd72be-4a87-48d4-9e27-0a983a2dd93e", "label": "a", "points": [[38, 6.5], [38, 343.3], [533, 343.3], [533, 6.5]], "color": "yellow"}, {"id": "944c2e34-a8ea-42d3-ad45-a1cdd0af5f92", "label": "b", "points": [[554.9, 4.8], [554.9, 341.6], [1050, 341.6], [1050, 4.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomography", "start": 19, "end": 29, "id": 4}, {"text": "on", "start": 30, "end": 32, "id": 5}, {"text": "admission", "start": 33, "end": 42, "id": 6}, {"text": ".", "start": 42, "end": 43, "id": 7}, {"text": "A", "start": 44, "end": 45, "id": 8}, {"text": ")", "start": 45, "end": 46, "id": 9}, {"text": "Pancreatic", "start": 47, "end": 57, "id": 10}, {"text": "sweling", "start": 58, "end": 65, "id": 11}, {"text": "and", "start": 66, "end": 69, "id": 12}, {"text": "necrosis", "start": 70, "end": 78, "id": 13}, {"text": "near", "start": 79, "end": 83, "id": 14}, {"text": "the", "start": 84, "end": 87, "id": 15}, {"text": "pancreas", "start": 88, "end": 96, "id": 16}, {"text": ".", "start": 96, "end": 97, "id": 17}, {"text": "B", "start": 98, "end": 99, "id": 18}, {"text": ")", "start": 99, "end": 100, "id": 19}, {"text": "Cystic", "start": 101, "end": 107, "id": 20}, {"text": "structure", "start": 108, "end": 117, "id": 21}, {"text": "(", "start": 118, "end": 119, "id": 22}, {"text": "arrow", "start": 119, "end": 124, "id": 23}, {"text": ")", "start": 124, "end": 125, "id": 24}, {"text": "near", "start": 126, "end": 130, "id": 25}, {"text": "the", "start": 131, "end": 134, "id": 26}, {"text": "galbladder", "start": 135, "end": 145, "id": 27}, {"text": "and", "start": 146, "end": 149, "id": 28}, {"text": "antrum", "start": 150, "end": 156, "id": 29}, {"text": ".", "start": 156, "end": 157, "id": 30}]}
{"pdf_hash": "5528ed0270bf1cc60c3a2ef884121d1d2f25ace0", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Ex vivo imaging. 7-tesla MRI of the same globe after enucleation. Prelaminar optic nerve extension is detectable ( a ). Photomicrograph of a pupil-optic nerve section with comparable axial orientation. Choroidal melanoma is seen impinging on the prelaminar optic nerve ( b ; HE, original magnification \u00d740).", "width": 934, "height": 562, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "d2182e77-ff9c-4b4a-9b04-79c36d5f787f", "label": "a", "points": [[3.7, 2.7], [3.7, 557.5], [458.2, 557.5], [458.2, 2.7]], "color": "yellow"}, {"id": "c0ff0296-2d13-4245-9793-1276b46f9909", "label": "b", "points": [[471.5, 5.7], [471.5, 560.4], [927.4, 560.4], [927.4, 5.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Ex", "start": 8, "end": 10, "id": 4}, {"text": "vivo", "start": 11, "end": 15, "id": 5}, {"text": "imaging", "start": 16, "end": 23, "id": 6}, {"text": ".", "start": 23, "end": 24, "id": 7}, {"text": "7-tesla", "start": 25, "end": 32, "id": 8}, {"text": "MRI", "start": 33, "end": 36, "id": 9}, {"text": "of", "start": 37, "end": 39, "id": 10}, {"text": "the", "start": 40, "end": 43, "id": 11}, {"text": "same", "start": 44, "end": 48, "id": 12}, {"text": "globe", "start": 49, "end": 54, "id": 13}, {"text": "after", "start": 55, "end": 60, "id": 14}, {"text": "enucleation", "start": 61, "end": 72, "id": 15}, {"text": ".", "start": 72, "end": 73, "id": 16}, {"text": "Prelaminar", "start": 74, "end": 84, "id": 17}, {"text": "optic", "start": 85, "end": 90, "id": 18}, {"text": "nerve", "start": 91, "end": 96, "id": 19}, {"text": "extension", "start": 97, "end": 106, "id": 20}, {"text": "is", "start": 107, "end": 109, "id": 21}, {"text": "detectable", "start": 110, "end": 120, "id": 22}, {"text": "(", "start": 121, "end": 122, "id": 23}, {"text": "a", "start": 123, "end": 124, "id": 24}, {"text": ")", "start": 125, "end": 126, "id": 25}, {"text": ".", "start": 126, "end": 127, "id": 26}, {"text": "Photomicrograph", "start": 128, "end": 143, "id": 27}, {"text": "of", "start": 144, "end": 146, "id": 28}, {"text": "a", "start": 147, "end": 148, "id": 29}, {"text": "pupil", "start": 149, "end": 154, "id": 30}, {"text": "-", "start": 154, "end": 155, "id": 31}, {"text": "optic", "start": 155, "end": 160, "id": 32}, {"text": "nerve", "start": 161, "end": 166, "id": 33}, {"text": "section", "start": 167, "end": 174, "id": 34}, {"text": "with", "start": 175, "end": 179, "id": 35}, {"text": "comparable", "start": 180, "end": 190, "id": 36}, {"text": "axial", "start": 191, "end": 196, "id": 37}, {"text": "orientation", "start": 197, "end": 208, "id": 38}, {"text": ".", "start": 208, "end": 209, "id": 39}, {"text": "Choroidal", "start": 210, "end": 219, "id": 40}, {"text": "melanoma", "start": 220, "end": 228, "id": 41}, {"text": "is", "start": 229, "end": 231, "id": 42}, {"text": "seen", "start": 232, "end": 236, "id": 43}, {"text": "impinging", "start": 237, "end": 246, "id": 44}, {"text": "on", "start": 247, "end": 249, "id": 45}, {"text": "the", "start": 250, "end": 253, "id": 46}, {"text": "prelaminar", "start": 254, "end": 264, "id": 47}, {"text": "optic", "start": 265, "end": 270, "id": 48}, {"text": "nerve", "start": 271, "end": 276, "id": 49}, {"text": "(", "start": 277, "end": 278, "id": 50}, {"text": "b", "start": 279, "end": 280, "id": 51}, {"text": ";", "start": 281, "end": 282, "id": 52}, {"text": "HE", "start": 283, "end": 285, "id": 53}, {"text": ",", "start": 285, "end": 286, "id": 54}, {"text": "original", "start": 287, "end": 295, "id": 55}, {"text": "magnification", "start": 296, "end": 309, "id": 56}, {"text": "\u00d740", "start": 310, "end": 313, "id": 57}, {"text": ")", "start": 313, "end": 314, "id": 58}, {"text": ".", "start": 314, "end": 315, "id": 59}]}
{"pdf_hash": "4bcc7d3c64a27638a32d3231659dc57ff07d86b6", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4 18 F-fluorodeoxyglucose positron emission tomography-computerized tomography scans of the gastrointestinal stromal tumors recurrence. Serial 18 F-FDG PET-CT scans showed submucosal, solid lesions in jejunum (SUVmax: 1.68-1.50) (A, B) and ileum (SUVmax: 4.69) (C) with maximum 2 cm in diameter, consisted with GIST recurrence on the follow-up (arrows). 18 F-FDG: 18 F-fluorodeoxyglucose; PET-CT: Positron emission tomography-computerized tomography; GIST: Gastrointestinal stromal tumors.", "width": 1196, "height": 394, "subcaptions": {"b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "a": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "c": [49, 50, 51, 52, 53, 54, 55, 56, 57]}, "subfigures": [{"id": "8e5a43ef-ab47-48dd-84a6-533921aa05a9", "label": "a", "points": [[4.3, 9.2], [4.3, 389], [389.8, 389], [389.8, 9.2]], "color": "yellow"}, {"id": "1c6552a6-63ce-4cd6-9811-c032894406da", "label": "c", "points": [[813, 1.6], [813, 387.1], [1192.8, 387.1], [1192.8, 1.6]], "color": "magenta"}, {"id": "fe6de437-ae65-423c-90d8-44d4c10072eb", "label": "b", "points": [[401.1, 7.3], [401.1, 387.1], [792.2, 387.1], 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{"pdf_hash": "61e1b20b214f9151de8a29dfd3344362de3d579b", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 DAPI nuclear staining (blue) and TUNEL assay (green) of mouse blastocysts from the control group (A, A1) with nucleus DNA fragmentation index of 18.5% and the experimental group (B, B1) group with nucleus DNA fragmentation index of 74.5%", "width": 868, "height": 876, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [3, 4, 5, 6, 7, 8, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [32, 33, 34, 10, 11, 12, 13, 14, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "d": [10, 11, 12, 13, 14, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52]}, "subfigures": [{"id": "4d0da2e7-9583-44b6-8263-322467a16bcb", "label": "a", "points": [[1.8, 1.2], [1.8, 438.6], [431, 438.6], [431, 1.2]], "color": "yellow"}, {"id": "1b91ee8f-16e0-4cc6-9f64-ed3909dd2f49", "label": "b", "points": [[443.3, 5.3], [443.3, 429], [857.4, 429], [857.4, 5.3]], "color": "magenta"}, {"id": "e88f14ec-4704-4df4-9b99-2477d56cec48", "label": "c", "points": [[5.9, 441.3], [5.9, 869.2], [426.8, 869.2], [426.8, 441.3]], "color": "cyan"}, {"id": "def57ece-d8bf-4621-ada6-bdefbaee4d17", "label": "d", "points": [[443.3, 441.3], [443.3, 870.5], [867, 870.5], [867, 441.3]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "DAPI", "start": 7, "end": 11, "id": 3}, {"text": "nuclear", "start": 12, "end": 19, "id": 4}, {"text": "staining", "start": 20, "end": 28, "id": 5}, {"text": "(", "start": 29, "end": 30, "id": 6}, {"text": "blue", "start": 30, "end": 34, "id": 7}, {"text": ")", "start": 34, "end": 35, "id": 8}, {"text": "and", "start": 36, "end": 39, "id": 9}, {"text": "TUNEL", "start": 40, "end": 45, "id": 10}, {"text": "assay", "start": 46, "end": 51, "id": 11}, {"text": "(", "start": 52, "end": 53, "id": 12}, {"text": "green", "start": 53, "end": 58, "id": 13}, {"text": ")", "start": 58, "end": 59, "id": 14}, {"text": "of", "start": 60, "end": 62, "id": 15}, {"text": "mouse", "start": 63, "end": 68, "id": 16}, {"text": "blastocysts", "start": 69, "end": 80, "id": 17}, {"text": "from", "start": 81, "end": 85, "id": 18}, {"text": "the", "start": 86, "end": 89, "id": 19}, {"text": "control", "start": 90, "end": 97, "id": 20}, {"text": "group", "start": 98, "end": 103, "id": 21}, {"text": "(", "start": 104, "end": 105, "id": 22}, {"text": "A", "start": 105, "end": 106, "id": 23}, {"text": ",", "start": 106, "end": 107, "id": 24}, {"text": "A1", "start": 108, "end": 110, "id": 25}, {"text": ")", "start": 110, "end": 111, "id": 26}, {"text": "with", "start": 112, "end": 116, "id": 27}, {"text": "nucleus", "start": 117, "end": 124, "id": 28}, {"text": "DNA", "start": 125, "end": 128, "id": 29}, {"text": "fragmentation", "start": 129, "end": 142, "id": 30}, {"text": "index", "start": 143, "end": 148, "id": 31}, {"text": "of", "start": 149, "end": 151, "id": 32}, {"text": "18.5", "start": 152, "end": 156, "id": 33}, {"text": "%", "start": 156, "end": 157, "id": 34}, {"text": "and", "start": 158, "end": 161, "id": 35}, {"text": "the", "start": 162, "end": 165, "id": 36}, {"text": "experimental", "start": 166, "end": 178, "id": 37}, {"text": "group", "start": 179, "end": 184, "id": 38}, {"text": "(", "start": 185, "end": 186, "id": 39}, {"text": "B", "start": 186, "end": 187, "id": 40}, {"text": ",", "start": 187, "end": 188, "id": 41}, {"text": "B1", "start": 189, "end": 191, "id": 42}, {"text": ")", "start": 191, "end": 192, "id": 43}, {"text": "group", "start": 193, "end": 198, "id": 44}, {"text": "with", "start": 199, "end": 203, "id": 45}, {"text": "nucleus", "start": 204, "end": 211, "id": 46}, {"text": "DNA", "start": 212, "end": 215, "id": 47}, {"text": "fragmentation", "start": 216, "end": 229, "id": 48}, {"text": "index", "start": 230, "end": 235, "id": 49}, {"text": "of", "start": 236, "end": 238, "id": 50}, {"text": "74.5", "start": 239, "end": 243, "id": 51}, {"text": "%", "start": 243, "end": 244, "id": 52}]}
{"pdf_hash": "ed06c8a55c4b7d411ea440436c145c6c97bfee64", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Left: The maximum diameter obtained with US dual plane imaging. Right: The 3D-US AAA reconstruction showing the perpendicular cross sections (blue) with the maximal diameter perpendicular to the centreline and the perpendicular cross sections (yellow) with the maximal partial volume covering 60 mm of the centreline. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)", "width": 1394, "height": 492, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14], "b": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "a7729ce7-ccdc-4935-baf7-223cd72e18e9", "label": "a", "points": [[35.9, 1.9], [35.9, 471], [388.2, 471], [388.2, 1.9]], "color": "yellow"}, {"id": "220a7db6-a496-4efd-8a9e-61aa8d1ffdc8", "label": "a", "points": [[399.2, 1.9], [399.2, 479.8], [705.4, 479.8], [705.4, 1.9]], "color": "cyan"}, {"id": "c1d372af-468c-49fe-9d36-a6f4fcc5305b", "label": "b", "points": [[709.8, 8.5], [709.8, 215.5], [1062.1, 215.5], [1062.1, 8.5]], "color": "magenta"}, {"id": "ad615667-fef2-4321-ad1c-501945e90290", "label": "b", "points": [[1066.5, 1.9], [1066.5, 219.9], [1366, 219.9], 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{"pdf_hash": "b922deac26901e36c1fd4a25e187a06daaf68a0f", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "FIG. 5. Utricularia nelumbifolia. Cell\u2013cell contact via plasmodesmata in placental nutritive tissue: the contact points between nuclear projections and cell membrane. (A, B) Ultrastructural details. CW, cell wall; D, dictyosome; NP, nuclear projection; black arrows mark plasmodesmata; red arrows point to the cell membrane. Tissue prepared for the SBEM method. Scale bars in (A) and (B) \u00bc 0\ufffd55lm. (C) Three-dimensional reconstruction showing the association of nuclear projections (in green) with the endoplasmic reticulum and plasmodesmata (both shown in red). Background: a part of a single microphotograph showing the cell ultrastructure. 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{"pdf_hash": "ced85e779a5e2c3e462f67fc067ff5df3a5ceeb7", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Computed tomography (CT) images for case 1 on the day of surgery. Head CT scans show crescent-shaped, mixed shadows of high and low densities in the right frontal, temporal and parietal lobes. The drainage tube extends outside the brain. The right ventricle is smaller and the bilateral corona radiata show small, low-density shadows with clear boundaries. 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{"pdf_hash": "bab30e2473bf9c6315ab21c2dd109f74962244a2", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2: (a) Transverse section of Helleborus niger \u2013 ground plan. AC: Air-chamber, Fi: Fissue in the periderm, IC: Inner cortex, Pe: Periderm, Pi: Pith, Ph: Pholeum, X: Xyleum. (b) Transverse section of Helleborus niger \u2013 A sector enlarged. AC: Air-chamber, Fi: Fissue in the periderm, IC: Inner cortex, Pe: Periderm, Ph: Pholeum, X: Xyleum. (c) Transverse section of Helleborus niger \u2013 periderm zone and xylem cylinder. 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{"pdf_hash": "6910997ef48eb89dad2c14d677316d15b95e4c47", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3. Ultrasound and MRI scan of the patient after the biopsy. The ultrasound exam on POD 1 (A) and MRI on POD 3 (B) show no sign of hematoma and ascites.", "width": 682, "height": 1054, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22], "b": [24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "45ffcff6-f351-4697-ad0d-3147d9d99437", "label": "a", "points": [[28.3, 21.4], [28.3, 535.3], [652.1, 535.3], [652.1, 21.4]], "color": "yellow"}, {"id": "afb58b25-c187-4d0d-b181-bb0391043dd5", "label": "b", "points": [[25.1, 553.1], [25.1, 1033.6], [658.6, 1033.6], [658.6, 553.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Ultrasound", "start": 10, "end": 20, "id": 3}, {"text": "and", "start": 21, "end": 24, "id": 4}, {"text": "MRI", "start": 25, "end": 28, "id": 5}, {"text": "scan", "start": 29, "end": 33, "id": 6}, {"text": "of", "start": 34, "end": 36, "id": 7}, {"text": "the", "start": 37, "end": 40, "id": 8}, {"text": "patient", "start": 41, "end": 48, "id": 9}, {"text": "after", "start": 49, "end": 54, "id": 10}, {"text": "the", "start": 55, "end": 58, "id": 11}, {"text": "biopsy", "start": 59, "end": 65, "id": 12}, {"text": ".", "start": 65, "end": 66, "id": 13}, {"text": "The", "start": 67, "end": 70, "id": 14}, {"text": "ultrasound", "start": 71, "end": 81, "id": 15}, {"text": "exam", "start": 82, "end": 86, "id": 16}, {"text": "on", "start": 87, "end": 89, "id": 17}, {"text": "POD", "start": 90, "end": 93, "id": 18}, {"text": "1", "start": 94, "end": 95, "id": 19}, {"text": "(", "start": 96, "end": 97, "id": 20}, {"text": "A", "start": 97, "end": 98, "id": 21}, {"text": ")", "start": 98, "end": 99, "id": 22}, {"text": "and", "start": 100, "end": 103, "id": 23}, {"text": "MRI", "start": 104, "end": 107, "id": 24}, {"text": "on", "start": 108, "end": 110, "id": 25}, {"text": "POD", "start": 111, "end": 114, "id": 26}, {"text": "3", "start": 115, "end": 116, "id": 27}, {"text": "(", "start": 117, "end": 118, "id": 28}, {"text": "B", "start": 118, "end": 119, "id": 29}, {"text": ")", "start": 119, "end": 120, "id": 30}, {"text": "show", "start": 121, "end": 125, "id": 31}, {"text": "no", "start": 126, "end": 128, "id": 32}, {"text": "sign", "start": 129, "end": 133, "id": 33}, {"text": "of", "start": 134, "end": 136, "id": 34}, {"text": "hematoma", "start": 137, "end": 145, "id": 35}, {"text": "and", "start": 146, "end": 149, "id": 36}, {"text": "ascites", "start": 150, "end": 157, "id": 37}, {"text": ".", "start": 157, "end": 158, "id": 38}]}
{"pdf_hash": "347e62e1b6450578ca820a0ff7b9cef7a89ea7d2", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Evaluation of hepatic steatosis using unenhanced CT scan. (A) Unenhanced transverse CT scan of normal liver shows attenuation value of liver parenchyma is 57 HU, slightly higher than that of spleen parenchyma of 48 HU. Calculated CTL-S is 9. (B) Unenhanced transverse CT scan of fatty liver shows attenuation value of liver parenchyma is -6 HU, lower than that of spleen parenchyma of 51 HU. Calculated CTL-S is -57, indicating the presence of moderate to severe degree hepatic steatosis. CT, computed tomography. 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{"pdf_hash": "9504e007282dc11bbdf8b02ca2ebde69fce332bf", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. (A) Low-dose electron micrographs of native tubular membranes from Rb.sphaeroides. Samples were negatively stained with 1% uranyl acetate. Bar \u03ed 100 nm for all the tubes. (B) Fourier transform of one tube from digitized scan. The arrow indicates the resolution at 25 \u00c5. (C) Filtered image from masked Fourier transform of electron micrograph. Bar \u03ed 200 \u00c5.", "width": 1290, "height": 1296, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57], "c": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "3f9cfb72-c0b1-4026-a15d-e0000ed54e8c", "label": "a", "points": [[37.8, -0.3], [37.8, 1259], [659.3, 1259], [659.3, -0.3]], "color": "yellow"}, {"id": "de085a9a-91ee-41da-ad44-6ea377cdc860", "label": "b", "points": [[665.4, 5.8], [665.4, 621.2], [1284.9, 621.2], [1284.9, 5.8]], "color": "cyan"}, {"id": "915844e3-348d-4fa9-ac31-96a2fad10a40", "label": "c", "points": [[665.4, 631.4], [665.4, 1259], [1280.8, 1259], [1280.8, 631.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Low", "start": 12, "end": 15, "id": 7}, {"text": "-", "start": 15, "end": 16, "id": 8}, {"text": "dose", "start": 16, "end": 20, "id": 9}, {"text": "electron", "start": 21, "end": 29, "id": 10}, {"text": "micrographs", "start": 30, "end": 41, "id": 11}, {"text": "of", "start": 42, "end": 44, "id": 12}, {"text": "native", "start": 45, "end": 51, "id": 13}, {"text": "tubular", "start": 52, "end": 59, "id": 14}, {"text": "membranes", "start": 60, "end": 69, "id": 15}, {"text": "from", "start": 70, "end": 74, "id": 16}, {"text": "Rb.sphaeroides", "start": 75, "end": 89, "id": 17}, {"text": ".", "start": 89, "end": 90, "id": 18}, {"text": "Samples", "start": 91, "end": 98, "id": 19}, {"text": "were", "start": 99, "end": 103, "id": 20}, {"text": "negatively", "start": 104, "end": 114, "id": 21}, {"text": "stained", "start": 115, "end": 122, "id": 22}, {"text": "with", "start": 123, "end": 127, "id": 23}, {"text": "1", "start": 128, "end": 129, "id": 24}, {"text": "%", "start": 129, "end": 130, "id": 25}, {"text": "uranyl", "start": 131, "end": 137, "id": 26}, {"text": "acetate", "start": 138, "end": 145, "id": 27}, {"text": ".", "start": 145, "end": 146, "id": 28}, {"text": "Bar", "start": 147, "end": 150, "id": 29}, {"text": "\u03ed", "start": 151, "end": 152, "id": 30}, {"text": "100", "start": 153, "end": 156, "id": 31}, {"text": "nm", "start": 157, "end": 159, "id": 32}, {"text": "for", "start": 160, "end": 163, "id": 33}, {"text": "all", "start": 164, "end": 167, "id": 34}, {"text": "the", "start": 168, "end": 171, "id": 35}, {"text": "tubes", "start": 172, "end": 177, "id": 36}, {"text": ".", "start": 177, "end": 178, "id": 37}, {"text": "(", "start": 179, "end": 180, "id": 38}, {"text": "B", "start": 180, "end": 181, "id": 39}, {"text": ")", "start": 181, "end": 182, "id": 40}, {"text": "Fourier", "start": 183, "end": 190, "id": 41}, {"text": "transform", "start": 191, "end": 200, "id": 42}, {"text": "of", "start": 201, "end": 203, "id": 43}, {"text": "one", "start": 204, "end": 207, "id": 44}, {"text": "tube", "start": 208, "end": 212, "id": 45}, {"text": "from", "start": 213, "end": 217, "id": 46}, {"text": "digitized", "start": 218, "end": 227, "id": 47}, {"text": "scan", "start": 228, "end": 232, "id": 48}, {"text": ".", "start": 232, "end": 233, "id": 49}, {"text": "The", "start": 234, "end": 237, "id": 50}, {"text": "arrow", "start": 238, "end": 243, "id": 51}, {"text": "indicates", "start": 244, "end": 253, "id": 52}, {"text": "the", "start": 254, "end": 257, "id": 53}, {"text": "resolution", "start": 258, "end": 268, "id": 54}, {"text": "at", "start": 269, "end": 271, "id": 55}, {"text": "25", "start": 272, "end": 274, "id": 56}, {"text": "\u00c5.", "start": 275, "end": 277, "id": 57}, {"text": "(", "start": 278, "end": 279, "id": 58}, {"text": "C", "start": 279, "end": 280, "id": 59}, {"text": ")", "start": 280, "end": 281, "id": 60}, {"text": "Filtered", "start": 282, "end": 290, "id": 61}, {"text": "image", "start": 291, "end": 296, "id": 62}, {"text": "from", "start": 297, "end": 301, "id": 63}, {"text": "masked", "start": 302, "end": 308, "id": 64}, {"text": "Fourier", "start": 309, "end": 316, "id": 65}, {"text": "transform", "start": 317, "end": 326, "id": 66}, {"text": "of", "start": 327, "end": 329, "id": 67}, {"text": "electron", "start": 330, "end": 338, "id": 68}, {"text": "micrograph", "start": 339, "end": 349, "id": 69}, {"text": ".", "start": 349, "end": 350, "id": 70}, {"text": "Bar", "start": 351, "end": 354, "id": 71}, {"text": "\u03ed", "start": 355, "end": 356, "id": 72}, {"text": "200", "start": 357, "end": 360, "id": 73}, {"text": "\u00c5.", "start": 361, "end": 363, "id": 74}]}
{"pdf_hash": "e6c2899093709a0a02326db04e5c1ddae710e3a2", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Immunofluorescence analysis of CLDN19 protein localization in the kidney. Cryostat sagittal sections (10 m) from WT mouse kidneys (A) (Right, high magnification) show CLDN19 localization in the TJs of TAL tubules in the corticomedullary rays (CMR). In CLDN16 KD mouse kidneys, CLDN19 staining is completely lost in TJs of the TAL (B). A strong intracellular background is seen in both WT and CLDN16 KD specimens. In CLDN19 KD mouse kidneys, CLDN19 staining disappears from both intracellular and junctional areas in the TAL (C).", "width": 898, "height": 1250, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "b": [64, 65, 66, 67, 68, 69, 70, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63], "c": [85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106]}, "subfigures": [{"id": "0fde3c47-9af2-4440-a777-08e805e12c84", "label": "a", "points": [[39.1, -0.2], [39.1, 429.6], [617.8, 429.6], [617.8, -0.2]], "color": "yellow"}, {"id": "59cf0355-d8aa-4211-8131-93138579bf61", "label": "a", "points": [[623.5, 1.2], [623.5, 432.4], [885.9, 432.4], [885.9, 1.2]], "color": "cyan"}, {"id": "726f6c9e-1867-425c-b064-c81ff0e04071", "label": "b", "points": [[41.9, 438.1], [41.9, 850.9], [304.3, 850.9], [304.3, 438.1]], "color": "magenta"}, {"id": 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{"pdf_hash": "35a90311969ec56e5b194a7f9c4803358c64a099", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5. Ptc is required for Hh-promoted Sxl nuclear entry. (A-F) Sxl nuclear levels are reduced in ptc -clones: (A-C) ptc 16 clones as marked by En expression (red, A) show decreased nuclear Sxl (green, B); merged image (C). Arrowhead marks where Sxl is nuclear between ptc negative clones. Scale bar: 20 \u00b5m. (D-F) ptc S2 clones marked by lack of \u03b2-gal expression (red, D) show decreased nuclear Sxl (green, panel E); merged image (F). Arrowhead marks where nuclear Sxl is absent between ptc negative clones with this amorphic allele that is capable of binding to Hh. (G-I) PtcD584N expressed in dorsal compartment of wing disc using the apterousGAL4 driver. Full-length Ci (red, G) and Sxl (green, H) and merged image (I). Note the weak signal of Sxl in the anterior dorsal compartment in both the wing pouch as well as notum because of decreased nuclear levels of the protein. Arrowhead points to the AP and dorsal/ventral boundary meeting point. The arrow indicates the overgrowth of disc in the anterior compartment as a result of the dominant negative effect of the PtcD584N protein. Scale bar: 40 \u00b5m. (J-L) ptc 16 clones in a hh MRT background stained for Ci (J), Sxl (K). (L) Merged image of J and K. Image is of the anterior region distant from the AP boundary of an overgrown disc. Large arrowhead marks region of lower Ci levels more posterior to region that has ectopic Hh, which is reported by the presence of fulllength Ci (arrow). Note the brighter punctate signal for Sxl marking higher nuclear levels where there is an increase in levels of full-length Ci. ptc -clones have lowered levels of Ci (some of the clones, which are round, are marked by small arrowheads) because of the induction of en which inhibits Ci transcription. As seen for ptc 16 -only clones, the levels of nuclear Sxl within the clones is lowered. Scale bar: 20 \u00b5m. 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{"pdf_hash": "ea57f9354e89c174a2e3010f0417093e0ae3d677", "fig_key": "Figure5", "fig_uri": "15-Figure5-1.png", "text": "Figure 5. Magnetic resonance images (MRI) and fundus images from a supposedly healthy subject (male, 51 years old) with discrete focal lesions in the brain without visible or detectable ocular manifestations. TOP: MRI images showing mild to moderate white matter (WM) disease in the MRI image. The images show discrete focal lesions in anterior and posterior WM, focal confluence in posterior WM, and periventricular caps. BOTTOM: Fundus images annotated (see black arrows) showing arterio-venous crossings. The arterio-venous crossings are frequent in the average healthy population. 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{"pdf_hash": "3efd7d0704e5b1a7996f6ead70f91cc063f5b61f", "fig_key": "Figure10", "fig_uri": "12-Figure10-1.png", "text": "FIGURE 10 | Postnatal morphological changes in the mouse intersphenoidal synchondroses. Representative sagittal sections through the ISS at P21 (A), P28 (B), P76 (C) stained using hematoxylin, eosin (20x magnification). The hypertrophic (Hz) zone appears narrower by P28, and by P76 few hypertrophic cells can be distinguished. Mineralized tissue from the ectocranial surface of the caudal and rostral margins can be seen extending toward each other from P21 to P28 (filled arrowheads) and have bridged the ISS by P76.", "width": 1230, "height": 388, "subcaptions": {"a": [19, 20, 21, 22], "b": [24, 25, 26, 27], "c": [32, 29, 30, 31]}, "subfigures": [{"id": "edae6242-a0b5-4edc-8926-6d41793a52f2", "label": "a", "points": [[86.5, 28.8], [86.5, 374.7], [414.9, 374.7], [414.9, 28.8]], "color": "yellow"}, {"id": "b6dcff30-b7e8-4868-b68d-9362258bac54", "label": "b", "points": [[482.9, 30.8], [482.9, 376.6], [807.4, 376.6], [807.4, 30.8]], "color": "cyan"}, {"id": "e10fc465-63ee-4136-bc2d-27a4048e825d", "label": "c", "points": [[859.9, 36.6], [859.9, 378.6], [1186.3, 378.6], [1186.3, 36.6]], "color": "magenta"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "10", "start": 7, "end": 9, "id": 1}, {"text": "|", "start": 10, "end": 11, "id": 2}, {"text": "Postnatal", "start": 12, "end": 21, "id": 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{"pdf_hash": "a50fa6ee905416e2060cf29d1525275dffe83f4c", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Prediction of the invasion depth of the detected lesion by magnifying narrow-band imaging. (A) The lesion shows a capillary pattern characterized by a blind ending, lack of uniformity, and curtailed irregularly, which is similar to the Sano IIIA pattern. This lesion was confirmed as being an intraepithelial adenocarcinoma. (B) The slightly depressed center of the lesion shows loose vessel areas and an amorphous surface pattern. 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{"pdf_hash": "2b721c4d92c6854fbd03a38a1fb8d613036975b0", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "Fig 7. Papillary carcinoma in a 25 year old male presented with a palpable nodule in the right lobe. Transverse US image (a) showed a large hypoechoic nodule with multiple micro and macro calcifications and mild internal vascularity (b). FNA performed confirmed a papillary carcinoma.", "width": 632, "height": 364, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 24, 25, 26, 27, 28, 29, 30, 31], "b": [39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "4ddf23fe-57d5-4405-881c-d59bd5c8a341", "label": "a", "points": [[1.8, 0.9], [1.8, 324.9], [321.8, 324.9], [321.8, 0.9]], "color": "yellow"}, {"id": "73810f42-7419-4d55-9463-09ce43700a90", "label": "b", "points": [[327.8, 4.9], [327.8, 325.9], [625.8, 325.9], [625.8, 4.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "7", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Papillary", "start": 7, "end": 16, "id": 3}, {"text": "carcinoma", "start": 17, "end": 26, "id": 4}, {"text": "in", "start": 27, "end": 29, "id": 5}, {"text": "a", "start": 30, "end": 31, "id": 6}, {"text": "25", "start": 32, "end": 34, "id": 7}, {"text": "year", "start": 35, "end": 39, "id": 8}, {"text": "old", "start": 40, "end": 43, "id": 9}, {"text": "male", "start": 44, "end": 48, "id": 10}, {"text": "presented", "start": 49, "end": 58, "id": 11}, {"text": "with", "start": 59, "end": 63, "id": 12}, {"text": "a", "start": 64, "end": 65, "id": 13}, {"text": "palpable", "start": 66, "end": 74, "id": 14}, {"text": "nodule", "start": 75, "end": 81, "id": 15}, {"text": "in", "start": 82, "end": 84, "id": 16}, {"text": "the", "start": 85, "end": 88, "id": 17}, {"text": "right", "start": 89, "end": 94, "id": 18}, {"text": "lobe", "start": 95, "end": 99, "id": 19}, {"text": ".", "start": 99, "end": 100, "id": 20}, {"text": "Transverse", "start": 101, "end": 111, "id": 21}, {"text": "US", "start": 112, "end": 114, "id": 22}, {"text": "image", "start": 115, "end": 120, "id": 23}, {"text": "(", "start": 121, "end": 122, "id": 24}, {"text": "a", "start": 122, "end": 123, "id": 25}, {"text": ")", "start": 123, "end": 124, "id": 26}, {"text": "showed", "start": 125, "end": 131, "id": 27}, {"text": "a", "start": 132, "end": 133, "id": 28}, {"text": "large", "start": 134, "end": 139, "id": 29}, {"text": "hypoechoic", "start": 140, "end": 150, "id": 30}, {"text": "nodule", "start": 151, "end": 157, "id": 31}, {"text": "with", "start": 158, "end": 162, "id": 32}, {"text": "multiple", "start": 163, "end": 171, "id": 33}, {"text": "micro", "start": 172, "end": 177, "id": 34}, {"text": "and", "start": 178, "end": 181, "id": 35}, {"text": "macro", "start": 182, "end": 187, "id": 36}, {"text": "calcifications", "start": 188, "end": 202, "id": 37}, {"text": "and", "start": 203, "end": 206, "id": 38}, {"text": "mild", "start": 207, "end": 211, "id": 39}, {"text": "internal", "start": 212, "end": 220, "id": 40}, {"text": "vascularity", "start": 221, "end": 232, "id": 41}, {"text": "(", "start": 233, "end": 234, "id": 42}, {"text": "b", "start": 234, "end": 235, "id": 43}, {"text": ")", "start": 235, "end": 236, "id": 44}, {"text": ".", "start": 236, "end": 237, "id": 45}, {"text": "FNA", "start": 238, "end": 241, "id": 46}, {"text": "performed", "start": 242, "end": 251, "id": 47}, {"text": "confirmed", "start": 252, "end": 261, "id": 48}, {"text": "a", "start": 262, "end": 263, "id": 49}, {"text": "papillary", "start": 264, "end": 273, "id": 50}, {"text": "carcinoma", "start": 274, "end": 283, "id": 51}, {"text": ".", "start": 283, "end": 284, "id": 52}]}
{"pdf_hash": "6eddde2df2c6dcae2c204ea62f43a9f6b20d87da", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. From the left, axial CT, fused PET/CT, and PET images of a false negative was found at histology in a left inguino-femoral LN. CT=computed tomography, FD tomographic.", "width": 1330, "height": 354, "subcaptions": {"a": [8, 7], "b": [10, 11, 12, 13], "c": [16, 17]}, "subfigures": [{"id": "8dad4ccd-4d9b-47ac-aa62-970e60f8ab3f", "label": "a", "points": [[33.6, 21], [33.6, 315.2], [462.3, 315.2], [462.3, 21]], "color": "yellow"}, {"id": "a5833226-93a4-4f41-8152-977dabec767c", "label": "b", "points": [[468.6, 315.2], [468.6, 31.5], [884.6, 31.5], [884.6, 315.2]], "color": "cyan"}, {"id": "e726aa2b-a94b-45a7-8433-beeb74460223", "label": "c", "points": [[888.8, 31.5], [888.8, 319.4], [1309.1, 319.4], [1309.1, 31.5]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "From", "start": 10, "end": 14, "id": 3}, {"text": "the", "start": 15, "end": 18, "id": 4}, {"text": "left", "start": 19, "end": 23, "id": 5}, {"text": ",", "start": 23, "end": 24, "id": 6}, {"text": "axial", "start": 25, "end": 30, "id": 7}, {"text": "CT", "start": 31, "end": 33, "id": 8}, {"text": ",", "start": 33, "end": 34, "id": 9}, {"text": "fused", "start": 35, "end": 40, "id": 10}, {"text": "PET", "start": 41, "end": 44, "id": 11}, {"text": "/", "start": 44, "end": 45, "id": 12}, {"text": "CT", "start": 45, "end": 47, "id": 13}, {"text": ",", "start": 47, "end": 48, "id": 14}, {"text": "and", "start": 49, "end": 52, "id": 15}, {"text": "PET", "start": 53, "end": 56, "id": 16}, {"text": "images", "start": 57, "end": 63, "id": 17}, {"text": "of", "start": 64, "end": 66, "id": 18}, {"text": "a", "start": 67, "end": 68, "id": 19}, {"text": "false", "start": 69, "end": 74, "id": 20}, {"text": "negative", "start": 75, "end": 83, "id": 21}, {"text": "was", "start": 84, "end": 87, "id": 22}, {"text": "found", "start": 88, "end": 93, "id": 23}, {"text": "at", "start": 94, "end": 96, "id": 24}, {"text": "histology", "start": 97, "end": 106, "id": 25}, {"text": "in", "start": 107, "end": 109, "id": 26}, {"text": "a", "start": 110, "end": 111, "id": 27}, {"text": "left", "start": 112, "end": 116, "id": 28}, {"text": "inguino", "start": 117, "end": 124, "id": 29}, {"text": "-", "start": 124, "end": 125, "id": 30}, {"text": "femoral", "start": 125, "end": 132, "id": 31}, {"text": "LN", "start": 133, "end": 135, "id": 32}, {"text": ".", "start": 135, "end": 136, "id": 33}, {"text": "CT", "start": 137, "end": 139, "id": 34}, {"text": "=", "start": 139, "end": 140, "id": 35}, {"text": "computed", "start": 140, "end": 148, "id": 36}, {"text": "tomography", "start": 149, "end": 159, "id": 37}, {"text": ",", "start": 159, "end": 160, "id": 38}, {"text": "FD", "start": 161, "end": 163, "id": 39}, {"text": "tomographic", "start": 164, "end": 175, "id": 40}, {"text": ".", "start": 175, "end": 176, "id": 41}]}
{"pdf_hash": "3b0b9f5209cf493d770c14a1656109cd6f03e63d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) A plain abdominal radiograph showing the ileus. (B) The round defect was revealed with amidotrizoate sodium meglumine injected through an ileus tube (black arrows). (C) The round structure, with an acoustic shadow of 42 mm in diameter (white arrows). 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{"pdf_hash": "4c58f7097a231cb11bf5c7d884c38602710775a0", "fig_key": "Figure5", "fig_uri": "10-Figure5-1.png", "text": "Fig. 5. Treatment outcome of unilateral RB after PBT. Fundoscopic examination of a 5-year-old boy diagnosed with RB in the right eye. (A) Pre-PBT: endophytic mass obscuring the posterior pole with two satellite masses. (B) During PBT: following the delivery of 2340 cGy, the main mass at the posterior pole has partially regressed, whereas the smaller seeding masses have slightly increased in size. (C) Two weeks after PBT: the main mass has regressed while the seeding masses have remained stable. (D) Three months after PBT: masses have overall remained stable. (E) MRI findings before (left) and after (right) PBT: a lobulated contoured intraocular mass of the right orbit, present before PBT, absent after PBT. 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{"pdf_hash": "d11fca162edcf23d45fc207c1c08b84d57b7e68e", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Computed tomography image of the chest (transverse plane) showing the tumor extending from the chest wall and the right upper lobe (blue arrowheads) to the pulmonary vein and the left atrium (blue arrows). 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{"pdf_hash": "254e87ce17e6ac80a536164fefab2a7ce3aacde2", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 | Illustration of chronic window implants for awake imaging in adolescent and adult mice. (a,b) Images of a 3-mm cranial window implant over the primary visual cortex (V1) of an adolescent mouse, taken on the day of surgery (a; P22; anesthetized) and 4 d later (b; awake and head-restrained). (c\u2013i) Images of a 3-mm cranial window implant at a very posterior and lateral location in an adult mouse. (c) Skull outline of proposed craniotomy, extending laterally to the squamosal bone. (d) Image of the exposed brain submerged in sterile saline immediately after the craniotomy. (e) The implant appears clear and the brain appears healthy immediately after initial cranial window implant (day 0). Black arrow denotes the intersection of the transverse sinus and the caudal rhinal vein. (f) Image of the same implant as in e, but 117 d later, illustrating sustained window clarity. (g,h) Images before (g) and after (h) showing a demonstration of cranial window removal in the same mouse, 124 d after initial window implant. (i) Image demonstrating window clarity, 51 d after window replacement (Fig. 10). Experiments were approved by the Institutional Animal Care and Use Committee (IACUC) at Harvard Medical School (HMS; a,b) and Beth Israel Deaconess Medical Center (BIDMC; c\u2013i). 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{"pdf_hash": "9e04b3094c2e8a5efb92ec3a803f51adb58c276c", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. a, b) CT showed left renal arteriovenous fistula (black arrows) in a 43-year-old male after percutaneous nephrolithotomy; c, d) DSA showed AVF (white arrows), and AVF was closed with NBCA-Lipiodol mixture; e) angiograms showed no pathologic picture immediately after embolization.", "width": 1096, "height": 1684, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "c": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "d": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "e": [49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "05ba4ebd-2477-4988-98be-3a72f2cccaed", "label": "a", "points": [[1.7, 3.5], [1.7, 453.6], [543.7, 453.6], [543.7, 3.5]], "color": "yellow"}, {"id": "229d606f-f93d-4342-aaa7-ade3a027b5a7", "label": "b", "points": [[548.9, 453.6], [548.9, 3.5], [1094.3, 3.5], [1094.3, 453.6]], "color": "cyan"}, {"id": "30492e5e-474b-4580-a6d8-05b62b701168", "label": "c", "points": [[3.5, 1094.3], [3.5, 471], [514.2, 471], [514.2, 1094.3]], "color": "magenta"}, {"id": "301cd563-2b9d-4e6b-acd6-e26699ed2d9f", "label": "d", "points": [[517.7, 472.7], [517.7, 1089.1], [1090.8, 1089.1], [1090.8, 472.7]], "color": "springgreen"}, {"id": "4a3cdd21-8f5e-425a-bd96-641ebcb90574", "label": "e", "points": [[244.1, 1139.3], [244.1, 1655.3], [832.8, 1655.3], [832.8, 1139.3]], "color": "tomato"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "b", "start": 13, "end": 14, "id": 5}, {"text": ")", "start": 14, "end": 15, "id": 6}, {"text": "CT", "start": 16, "end": 18, "id": 7}, {"text": "showed", "start": 19, "end": 25, "id": 8}, {"text": "left", "start": 26, "end": 30, "id": 9}, {"text": "renal", "start": 31, "end": 36, "id": 10}, {"text": "arteriovenous", "start": 37, "end": 50, "id": 11}, {"text": "fistula", "start": 51, "end": 58, "id": 12}, {"text": "(", "start": 59, "end": 60, "id": 13}, {"text": "black", "start": 60, "end": 65, "id": 14}, {"text": "arrows", "start": 66, "end": 72, "id": 15}, {"text": ")", "start": 72, "end": 73, "id": 16}, {"text": "in", "start": 74, "end": 76, "id": 17}, {"text": "a", "start": 77, "end": 78, "id": 18}, {"text": "43-year", "start": 79, "end": 86, "id": 19}, {"text": "-", "start": 86, "end": 87, "id": 20}, {"text": "old", "start": 87, "end": 90, "id": 21}, {"text": "male", "start": 91, "end": 95, "id": 22}, {"text": "after", "start": 96, "end": 101, "id": 23}, {"text": "percutaneous", "start": 102, "end": 114, "id": 24}, {"text": "nephrolithotomy", "start": 115, "end": 130, "id": 25}, {"text": ";", "start": 130, "end": 131, "id": 26}, {"text": "c", "start": 132, "end": 133, "id": 27}, {"text": ",", "start": 133, "end": 134, "id": 28}, {"text": "d", "start": 135, "end": 136, "id": 29}, {"text": ")", "start": 136, "end": 137, "id": 30}, {"text": "DSA", "start": 138, "end": 141, "id": 31}, {"text": "showed", "start": 142, "end": 148, "id": 32}, {"text": "AVF", "start": 149, "end": 152, "id": 33}, {"text": "(", "start": 153, "end": 154, "id": 34}, {"text": "white", "start": 154, "end": 159, "id": 35}, {"text": "arrows", "start": 160, "end": 166, "id": 36}, {"text": ")", "start": 166, "end": 167, "id": 37}, {"text": ",", "start": 167, "end": 168, "id": 38}, {"text": "and", "start": 169, "end": 172, "id": 39}, {"text": "AVF", "start": 173, "end": 176, "id": 40}, {"text": "was", "start": 177, "end": 180, "id": 41}, {"text": "closed", "start": 181, "end": 187, "id": 42}, {"text": "with", "start": 188, "end": 192, "id": 43}, {"text": "NBCA", "start": 193, "end": 197, "id": 44}, {"text": "-", "start": 197, "end": 198, "id": 45}, {"text": "Lipiodol", "start": 198, "end": 206, "id": 46}, {"text": "mixture", "start": 207, "end": 214, "id": 47}, {"text": ";", "start": 214, "end": 215, "id": 48}, {"text": "e", "start": 216, "end": 217, "id": 49}, {"text": ")", "start": 217, "end": 218, "id": 50}, {"text": "angiograms", "start": 219, "end": 229, "id": 51}, {"text": "showed", "start": 230, "end": 236, "id": 52}, {"text": "no", "start": 237, "end": 239, "id": 53}, {"text": "pathologic", "start": 240, "end": 250, "id": 54}, {"text": "picture", "start": 251, "end": 258, "id": 55}, {"text": "immediately", "start": 259, "end": 270, "id": 56}, {"text": "after", "start": 271, "end": 276, "id": 57}, {"text": "embolization", "start": 277, "end": 289, "id": 58}, {"text": ".", "start": 289, "end": 290, "id": 59}]}
{"pdf_hash": "63c27ed843829ae5dd58b469be700c88b82a944b", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig 1. Overview of AC-maps, cardiac PET data and polar plots. Attenuation correction (AC) maps based on Dixon-VIBE sequence (a), the extended Dixon-VIBE sequence additionally using HUGE truncation correction and bone information (b), and the extended Dixon-VIBE sequence additionally using PET-based MLAA information (c). Red arrows depict differences between Dixon-VIBE only AC and improved AC-maps using HUGE, bone segmentation, and MLAA, respectively (b, c). Patient example studied in the fasted state (d-f) and patient example studied with a viability protocol (g-i) are shown. PET/MR fusion image (d, g) and PET short axis view (e, h) of the heart. A 17-segment polar plot (f, i) of the short-axis of the left ventricle was generated for each patient and each PET data reconstruction to evaluate the quantitative effect of improved AC on cardiac PET imaging. 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{"pdf_hash": "311288a7366c2e9530cc2ba4601da82672a4bdde", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Positron emission tomography/computed tomography (CT) findings. Hypermetabolic focus in the right nasopharynx (A) and hypopharynx (C). (B, D) CT without corresponding abnormalities. (E, F) Enlarged cervical nodes in left level II.", "width": 674, "height": 1108, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [32, 33, 34, 35, 36, 37, 38, 29, 30, 31], "c": [14, 15, 16, 17, 18, 24, 25, 26, 27, 28], "d": [32, 33, 34, 35, 36, 37, 38, 29, 30, 31], "e": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "f": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "1664b4bd-c80d-450e-8656-52ed0ebb7e74", "label": "a", "points": [[6.4, 2.1], [6.4, 359.9], [328, 359.9], [328, 2.1]], "color": "yellow"}, {"id": "618c828c-55bc-49aa-a7b1-f3aca522e577", "label": "b", "points": [[332.2, 358.8], [332.2, 5.3], [672.9, 5.3], [672.9, 358.8]], "color": "cyan"}, {"id": "052f4917-7ad9-4188-b0ae-4ed4e411be02", "label": "c", "points": [[10.6, 367.3], [10.6, 731.5], [322.6, 731.5], [322.6, 367.3]], "color": "magenta"}, {"id": "32e91238-ffe3-4595-9ae4-6a4ec5145d49", "label": "d", "points": [[332.2, 729.4], [332.2, 367.3], [671.9, 367.3], [671.9, 729.4]], "color": "springgreen"}, {"id": "0777de23-f244-444a-9285-b5964db16743", "label": "e", "points": [[9.6, 741.1], [9.6, 1090.3], [323.7, 1090.3], [323.7, 741.1]], "color": "tomato"}, {"id": "734852e0-0d0a-41df-a6ed-bfd24ba32f18", "label": "f", "points": [[335.4, 1091.4], [335.4, 739], [671.9, 739], [671.9, 1091.4]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Positron", "start": 10, "end": 18, "id": 3}, {"text": "emission", "start": 19, "end": 27, "id": 4}, {"text": "tomography", "start": 28, "end": 38, "id": 5}, {"text": "/", "start": 38, "end": 39, "id": 6}, {"text": "computed", "start": 39, "end": 47, "id": 7}, {"text": "tomography", "start": 48, "end": 58, "id": 8}, {"text": "(", "start": 59, "end": 60, "id": 9}, {"text": "CT", "start": 60, "end": 62, "id": 10}, {"text": ")", "start": 62, "end": 63, "id": 11}, {"text": "findings", "start": 64, "end": 72, "id": 12}, {"text": ".", "start": 72, "end": 73, "id": 13}, {"text": "Hypermetabolic", "start": 74, "end": 88, "id": 14}, {"text": "focus", "start": 89, "end": 94, "id": 15}, {"text": "in", "start": 95, "end": 97, "id": 16}, {"text": "the", "start": 98, "end": 101, "id": 17}, {"text": "right", "start": 102, "end": 107, "id": 18}, {"text": "nasopharynx", "start": 108, "end": 119, "id": 19}, {"text": "(", "start": 120, "end": 121, "id": 20}, {"text": "A", "start": 121, "end": 122, "id": 21}, {"text": ")", "start": 122, "end": 123, "id": 22}, {"text": "and", "start": 124, "end": 127, "id": 23}, {"text": "hypopharynx", "start": 128, "end": 139, "id": 24}, {"text": "(", "start": 140, "end": 141, "id": 25}, {"text": "C", "start": 141, "end": 142, "id": 26}, {"text": ")", "start": 142, "end": 143, "id": 27}, {"text": ".", "start": 143, "end": 144, "id": 28}, {"text": "(", "start": 145, "end": 146, "id": 29}, {"text": "B", "start": 146, "end": 147, "id": 30}, {"text": ",", "start": 147, "end": 148, "id": 31}, {"text": "D", "start": 149, "end": 150, "id": 32}, {"text": ")", "start": 150, "end": 151, "id": 33}, {"text": "CT", "start": 152, "end": 154, "id": 34}, {"text": "without", "start": 155, "end": 162, "id": 35}, {"text": "corresponding", "start": 163, "end": 176, "id": 36}, {"text": "abnormalities", "start": 177, "end": 190, "id": 37}, {"text": ".", "start": 190, "end": 191, "id": 38}, {"text": "(", "start": 192, "end": 193, "id": 39}, {"text": "E", "start": 193, "end": 194, "id": 40}, {"text": ",", "start": 194, "end": 195, "id": 41}, {"text": "F", "start": 196, "end": 197, "id": 42}, {"text": ")", "start": 197, "end": 198, "id": 43}, {"text": "Enlarged", "start": 199, "end": 207, "id": 44}, {"text": "cervical", "start": 208, "end": 216, "id": 45}, {"text": "nodes", "start": 217, "end": 222, "id": 46}, {"text": "in", "start": 223, "end": 225, "id": 47}, {"text": "left", "start": 226, "end": 230, "id": 48}, {"text": "level", "start": 231, "end": 236, "id": 49}, {"text": "II", "start": 237, "end": 239, "id": 50}, {"text": ".", "start": 239, "end": 240, "id": 51}]}
{"pdf_hash": "fe930b17bb8c316c9a76575967f9f3101d0c97b4", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Abdominal computed tomography (CT) scans before and after gemcitabine plus vinorelbine therapy. Abdominal CT scan before gemcitabine plus vinorelbine chemotherapy showed a soft-tissue tumor near the left adrenal gland (A), and a lymphadenopathy on the dorsal side of the inferior vena cava (B). 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{"pdf_hash": "52869be7ceed0bbd9a7106338d33e1e9e11908c6", "fig_key": "Figure7", "fig_uri": "12-Figure7-1.png", "text": "Fig 7. Imaging of HEK cells grown in microfluidic channels. HEK cells were imaged for 4 h with a Samsung Galaxy S I9000 using the ATLIS with the humidifying module (recirculating-loop configuration) mounted on a Nikon TMS microscope with 10X magnification in the eyepiece and using a 20X objective. No signs of evaporation were detected in the microfluidic system and the cells moved and proliferated normally. White boxes delineate magnified areas shown in the bottom row. A proliferating cell can bee seen in the area marked by a yellow box. The lower channel was 250 \u03bcm across, while the narrower channels at the top were 125 \u03bcm wide. All channels were 100 \u03bcm in height. 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{"pdf_hash": "f04d73d95afaeb1219ef65df12f7a1d9d62a9216", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Accumulation and infiltration of iPS-ML in pre-established tumor tissues in mouse peritoneal cavity. A. GFP-expressing NUGC-4 cells (5 610 6 cells/mouse) were injected into the peritoneal cavity of SCID mice. After 15 days, iPS-ML labeled with fluorescent PKH26 were injected i.p. into the mice (3610 6 cells/mouse). The mice were sacrificed the following day and subjected to fluorescence imaging analysis to determine the location of the NUGC-4-GFP tumors (excitation/emission: 475/520 nm) and PKH26-iPS-ML (excitation/emission: 550/600 nm). B. Tumor tissues in the greater omentum of the mice were isolated, and 20-mm thick frozen sections were made. The sections were analyzed on a fluorescence microscope, and a merged image with green fluorescence indicating NUGC-4/GFP cells and red fluorescence indicating PKH26-stained iPS-ML is shown. C, D Tissue sections were made by a similar procedure as for B, except that tPA was not used. A higher magnification view of the region surrounded by a dotted square in C is shown in D. doi:10.1371/journal.pone.0067567.g003", "width": 896, "height": 662, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112], "b": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "c": [166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 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{"pdf_hash": "87647c1648a7a1304e553195d2756c3a8c7b9d08", "fig_key": "Figure2", "fig_uri": "9-Figure2-1.png", "text": "Figure 2. Expression of BCL6, MUM1, and CD138 in monoclonal B-cell PTLDs. (A) Diffuse large B-cell lymphoma with centroblastic morphology displaying the BCL6 \u03e9 /MUM1 \u03ea /CD138 \u03ea phenotypic pattern. Mediumsized tumor cells show a nuclear staining pattern with the anti-BCL6 MoAb. Residual plasma cells show nuclear brown staining for anti-MUM1 antibody and cytoplasmic red staining for anti-CD138 MoAb (arrows). (B) Diffuse large B-cell lymphoma with centroblastic morphology displaying the BCL-6 \u03ea /MUM1 \u03e9 /CD138 \u03ea phenotypic pattern. Most neoplastic cells show strong nuclear immunoreactivity with the anti-MUM1 antibody. No BCL6 expression is detectable in the neoplastic population; residual plasma cells show cytoplasmic staining for anti-CD138 MoAb. Paraffin-embedded tissue sections, immunoperoxidase method (BCL6, MUM1), APAAP method (CD138), hematoxylin counterstain. Original magnification, \u03eb 250.", "width": 900, "height": 438, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80], "b": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "8a587023-8884-418a-ac91-891e778eceb7", "label": "a", "points": [[44.5, 45.3], [44.5, 228.7], [317.5, 228.7], [317.5, 45.3]], "color": "yellow"}, {"id": "164c7a03-8dcf-4ec2-b745-56d0f7d28170", "label": "a", "points": [[331.7, 43.9], [331.7, 227.3], [607.5, 227.3], [607.5, 43.9]], "color": "cyan"}, {"id": "a2df5c3c-0d31-4f70-a94e-f275302e2d8b", 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{"pdf_hash": "2ee194a19aefbe7e1965441dc831d33f34883a83", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Buried H-bonds and salt-bridges between apoE3 domains, with a focus on the major LDLR-binding region. The apoE3 is shown in ribbons and the side chains of the interacting residues in stick model. The NT domain is shown in light blue while the CT domain in pink. The side chains of the interacting residues in the major LDLR-binding region are shown in green, whereas the side chains of the other interacting residues are shown in brown. The salt-bridges and H-bonds are indicated with red dashed lines. (A) Detailed interdomain interactions of residues K157 and R158. (B) Detailed interdomain interactions of residues R134, R136, R142, K143, R145, K146, R147, and R150. 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{"pdf_hash": "ad463dff3e2499baced5e83c932b8f49836bf206", "fig_key": "Figure10", "fig_uri": "7-Figure10-1.png", "text": "Fig. 10. Incomplete lesion coverage in a 46-year-old woman. A laterally located mass (white circle) was partially included on the lateral view of automated breast ultrasonography (ABUS), hindering the complete characterization of the mass (upper and right lower column). 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{"pdf_hash": "58309451286b8f6ee2d444fbbbe945f60837cd2f", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Longitudinal course of computed tomography (CT) images of the chest. (A) CT showed diffuse centrilobular ground-glass opacities at 18 years; (B) at 22 years; (C) at 27 years, fibrotic changes in both upper lobes were recognized; and (D) at 30 years, the fibrosis changes deteriorated.", "width": 866, "height": 798, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [32, 33, 34, 35, 36, 37, 31], "c": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "d": [64, 65, 66, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "2b6101cc-b234-4400-9362-576c298876c8", "label": "a", "points": [[7.1, 1.8], [7.1, 265.9], [406.6, 265.9], [406.6, 1.8]], "color": "yellow"}, {"id": "d8956814-7f52-4a4e-ba8c-e7c724ea5991", "label": "b", "points": [[0.2, 282.3], [0.2, 538.1], [412, 538.1], [412, 282.3]], "color": "cyan"}, {"id": "c9dbd02a-80f7-4b94-a371-b6764fb58990", "label": "d", "points": [[4.3, 555.9], [4.3, 789.8], [421.6, 789.8], [421.6, 555.9]], "color": "magenta"}, {"id": "2abc78f7-18b6-43b1-b6fe-d23d6d347a21", "label": "c", "points": [[421.6, 279.1], [421.6, 788], [860.8, 788], [860.8, 279.1]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Longitudinal", "start": 10, "end": 22, "id": 3}, {"text": "course", "start": 23, "end": 29, "id": 4}, {"text": "of", "start": 30, "end": 32, "id": 5}, {"text": "computed", "start": 33, "end": 41, "id": 6}, {"text": "tomography", "start": 42, "end": 52, "id": 7}, {"text": "(", "start": 53, "end": 54, "id": 8}, {"text": "CT", "start": 54, "end": 56, "id": 9}, {"text": ")", "start": 56, "end": 57, "id": 10}, {"text": "images", "start": 58, "end": 64, "id": 11}, {"text": "of", "start": 65, "end": 67, "id": 12}, {"text": "the", "start": 68, "end": 71, "id": 13}, {"text": "chest", "start": 72, "end": 77, "id": 14}, {"text": ".", "start": 77, "end": 78, "id": 15}, {"text": "(", "start": 79, "end": 80, "id": 16}, {"text": "A", "start": 80, "end": 81, "id": 17}, {"text": ")", "start": 81, "end": 82, "id": 18}, {"text": "CT", "start": 83, "end": 85, "id": 19}, {"text": "showed", "start": 86, "end": 92, "id": 20}, {"text": "diffuse", "start": 93, "end": 100, "id": 21}, {"text": "centrilobular", "start": 101, "end": 114, "id": 22}, {"text": "ground", "start": 115, "end": 121, "id": 23}, {"text": "-", "start": 121, "end": 122, "id": 24}, {"text": "glass", "start": 122, "end": 127, "id": 25}, {"text": "opacities", "start": 128, "end": 137, "id": 26}, {"text": "at", "start": 138, "end": 140, "id": 27}, {"text": "18", "start": 141, "end": 143, "id": 28}, {"text": "years", "start": 144, "end": 149, "id": 29}, {"text": ";", "start": 149, "end": 150, "id": 30}, {"text": "(", "start": 151, "end": 152, "id": 31}, {"text": "B", "start": 152, "end": 153, "id": 32}, {"text": ")", "start": 153, "end": 154, "id": 33}, {"text": "at", "start": 155, "end": 157, "id": 34}, {"text": "22", "start": 158, "end": 160, "id": 35}, {"text": "years", "start": 161, "end": 166, "id": 36}, {"text": ";", "start": 166, "end": 167, "id": 37}, {"text": "(", "start": 168, "end": 169, "id": 38}, {"text": "C", "start": 169, "end": 170, "id": 39}, {"text": ")", "start": 170, "end": 171, "id": 40}, {"text": "at", "start": 172, "end": 174, "id": 41}, {"text": "27", "start": 175, "end": 177, "id": 42}, {"text": "years", "start": 178, "end": 183, "id": 43}, {"text": ",", "start": 183, "end": 184, "id": 44}, {"text": "fibrotic", "start": 185, "end": 193, "id": 45}, {"text": "changes", "start": 194, "end": 201, "id": 46}, {"text": "in", "start": 202, "end": 204, "id": 47}, {"text": "both", "start": 205, "end": 209, "id": 48}, {"text": "upper", "start": 210, "end": 215, "id": 49}, {"text": "lobes", "start": 216, "end": 221, "id": 50}, {"text": "were", "start": 222, "end": 226, "id": 51}, {"text": "recognized", "start": 227, "end": 237, "id": 52}, {"text": ";", "start": 237, "end": 238, "id": 53}, {"text": "and", "start": 239, "end": 242, "id": 54}, {"text": "(", "start": 243, "end": 244, "id": 55}, {"text": "D", "start": 244, "end": 245, "id": 56}, {"text": ")", "start": 245, "end": 246, "id": 57}, {"text": "at", "start": 247, "end": 249, "id": 58}, {"text": "30", "start": 250, "end": 252, "id": 59}, {"text": "years", "start": 253, "end": 258, "id": 60}, {"text": ",", "start": 258, "end": 259, "id": 61}, {"text": "the", "start": 260, "end": 263, "id": 62}, {"text": "fibrosis", "start": 264, "end": 272, "id": 63}, {"text": "changes", "start": 273, "end": 280, "id": 64}, {"text": "deteriorated", "start": 281, "end": 293, "id": 65}, {"text": ".", "start": 293, "end": 294, "id": 66}]}
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{"pdf_hash": "b6c62851a4d4326d2dcf042d3ddab1d0a91b436d", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4 Mass spectrometry imaging in negative ion mode of wheat seed at the soft dough stage. (a) The optical image of the 20 \u00b5m seed cross section shows the coleoptile/coleorhiza (Co), scutellum (Sc), the endosperm (E), the pericarp-seed coat region (PS), and crease (Cr). Scale bar 500 \u00b5m. (b) Overlay of ion images shows the tissue-specific spatial distributions of a polyphenol glycoside [M \u2212 H] \u2212 , m/z 563.14063 (green) detected in the embryonic protection sheath coleoptile/coleorhiza covering the main compartments namely shoot, plumules (first true leaves) and radicle; and a phosphatidylinositol [PI(34 : 2) \u2212 H] \u2212 , m/z 833.51855 (red) located in the scutellum and endosperm, but absent in the crease. 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{"pdf_hash": "2f67fc7f32512cd5636bfcd943cde5d7b8550e3d", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1: A CT scan 2 years (A) and 14 years (B) after the initial aortic repair. It shows the enlarged prosthesis diameter of 42 mm (black dotted arrows), which has remained stable over time. Compared with the original dimension, the cross-sectional area of the prosthesis increased by 96%, and the prosthesis wall tension by 40%.", "width": 470, "height": 904, "subcaptions": {"a": [6, 7, 8, 9, 10], "b": [12, 13, 14, 15, 16]}, "subfigures": [{"id": "730255e4-d235-4154-9ffc-052c74a7398c", "label": "a", "points": [[1, 3.8], [1, 447.8], [466, 447.8], [466, 3.8]], "color": "yellow"}, {"id": "38a2bbe0-ef39-4949-87d0-9943768fd274", "label": "b", "points": [[0, 460.8], [0, 902.9], [464, 902.9], [464, 460.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "CT", "start": 12, "end": 14, "id": 4}, {"text": "scan", "start": 15, "end": 19, "id": 5}, {"text": "2", "start": 20, "end": 21, "id": 6}, {"text": "years", "start": 22, "end": 27, "id": 7}, {"text": "(", "start": 28, "end": 29, "id": 8}, {"text": "A", "start": 29, "end": 30, "id": 9}, {"text": ")", "start": 30, "end": 31, "id": 10}, {"text": "and", "start": 32, "end": 35, "id": 11}, {"text": "14", "start": 36, "end": 38, "id": 12}, {"text": "years", "start": 39, "end": 44, "id": 13}, {"text": "(", "start": 45, "end": 46, "id": 14}, {"text": "B", "start": 46, "end": 47, "id": 15}, {"text": ")", "start": 47, "end": 48, "id": 16}, {"text": "after", "start": 49, "end": 54, "id": 17}, {"text": "the", "start": 55, "end": 58, "id": 18}, {"text": "initial", "start": 59, "end": 66, "id": 19}, {"text": "aortic", "start": 67, "end": 73, "id": 20}, {"text": "repair", "start": 74, "end": 80, "id": 21}, {"text": ".", "start": 80, "end": 81, "id": 22}, {"text": "It", "start": 82, "end": 84, "id": 23}, {"text": "shows", "start": 85, "end": 90, "id": 24}, {"text": "the", "start": 91, "end": 94, "id": 25}, {"text": "enlarged", "start": 95, "end": 103, "id": 26}, {"text": "prosthesis", "start": 104, "end": 114, "id": 27}, {"text": "diameter", "start": 115, "end": 123, "id": 28}, {"text": "of", "start": 124, "end": 126, "id": 29}, {"text": "42", "start": 127, "end": 129, "id": 30}, {"text": "mm", "start": 130, "end": 132, "id": 31}, {"text": "(", "start": 133, "end": 134, "id": 32}, {"text": "black", "start": 134, "end": 139, "id": 33}, {"text": "dotted", "start": 140, "end": 146, "id": 34}, {"text": "arrows", "start": 147, "end": 153, "id": 35}, {"text": ")", "start": 153, "end": 154, "id": 36}, {"text": ",", "start": 154, "end": 155, "id": 37}, {"text": "which", "start": 156, "end": 161, "id": 38}, {"text": "has", "start": 162, "end": 165, "id": 39}, {"text": "remained", "start": 166, "end": 174, "id": 40}, {"text": "stable", "start": 175, "end": 181, "id": 41}, {"text": "over", "start": 182, "end": 186, "id": 42}, {"text": "time", "start": 187, "end": 191, "id": 43}, {"text": ".", "start": 191, "end": 192, "id": 44}, {"text": "Compared", "start": 193, "end": 201, "id": 45}, {"text": "with", "start": 202, "end": 206, "id": 46}, {"text": "the", "start": 207, "end": 210, "id": 47}, {"text": "original", "start": 211, "end": 219, "id": 48}, {"text": "dimension", "start": 220, "end": 229, "id": 49}, {"text": ",", "start": 229, "end": 230, "id": 50}, {"text": "the", "start": 231, "end": 234, "id": 51}, {"text": "cross", "start": 235, "end": 240, "id": 52}, {"text": "-", "start": 240, "end": 241, "id": 53}, {"text": "sectional", "start": 241, "end": 250, "id": 54}, {"text": "area", "start": 251, "end": 255, "id": 55}, {"text": "of", "start": 256, "end": 258, "id": 56}, {"text": "the", "start": 259, "end": 262, "id": 57}, {"text": "prosthesis", "start": 263, "end": 273, "id": 58}, {"text": "increased", "start": 274, "end": 283, "id": 59}, {"text": "by", "start": 284, "end": 286, "id": 60}, {"text": "96", "start": 287, "end": 289, "id": 61}, {"text": "%", "start": 289, "end": 290, "id": 62}, {"text": ",", "start": 290, "end": 291, "id": 63}, {"text": "and", "start": 292, "end": 295, "id": 64}, {"text": "the", "start": 296, "end": 299, "id": 65}, {"text": "prosthesis", "start": 300, "end": 310, "id": 66}, {"text": "wall", "start": 311, "end": 315, "id": 67}, {"text": "tension", "start": 316, "end": 323, "id": 68}, {"text": "by", "start": 324, "end": 326, "id": 69}, {"text": "40", "start": 327, "end": 329, "id": 70}, {"text": "%", "start": 329, "end": 330, "id": 71}, {"text": ".", "start": 330, "end": 331, "id": 72}]}
{"pdf_hash": "bf8bb65b67edb510c4ac3a74896ca4a6922548b1", "fig_key": "Figure9", "fig_uri": "10-Figure9-1.png", "text": "Figure 9. Coronary CT angiography in a 55-year-old male with history of left main trunk, left anterior descending and circumflex artery stenting: two different reconstructions algorithms (standard in a and sharper in b) are performed using iterative reconstruction techniques and the smallest field of view (8cm). With the sharper reconstruction algorithm, higher image noise is seen as compared with the standard reconstruction, but more details of the proximal circumflex artery severe in-stent restenosis are seen (arrow in b), with a better correlation with catheter coronary angiography (arrow in c).", "width": 1398, "height": 670, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 32, 33, 34, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 36, 37, 38, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94], "c": [101, 102, 103, 104, 105, 106, 107, 108, 109]}, "subfigures": [{"id": "402b0a66-8fd5-4065-8c76-7b7a6232a56a", "label": 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{"pdf_hash": "f28d975060b0a3687fa39efc216a8d03aa2ea0b8", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2 Hip revision in the foregoing patient at 6 months postoperatively. A securely fixed acetabular component was confirmed during the revision surgery. Bone ingrowth was shown within the surface of acetabular component (a). b A trabecular metal acetabular component with decreased anteversion was shown on the radiograph after hip revision", "width": 852, "height": 556, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 26, 27, 28, 29, 30, 31], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "f7025dd3-000e-4129-aec9-e68536672023", "label": "a", "points": [[32.3, 18.8], [32.3, 519.6], [258.4, 519.6], [258.4, 18.8]], "color": "yellow"}, {"id": "06205d22-c2c5-4888-a5de-3ec68dbc97de", "label": "b", "points": [[265.2, 519.6], [265.2, 22.9], [815.7, 22.9], [815.7, 519.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Hip", "start": 7, "end": 10, "id": 3}, {"text": "revision", "start": 11, "end": 19, "id": 4}, {"text": "in", "start": 20, "end": 22, "id": 5}, {"text": "the", "start": 23, "end": 26, "id": 6}, {"text": "foregoing", "start": 27, "end": 36, "id": 7}, {"text": "patient", "start": 37, "end": 44, "id": 8}, {"text": "at", "start": 45, "end": 47, "id": 9}, {"text": "6", "start": 48, "end": 49, "id": 10}, {"text": "months", "start": 50, "end": 56, "id": 11}, {"text": "postoperatively", "start": 57, "end": 72, "id": 12}, {"text": ".", "start": 72, "end": 73, "id": 13}, {"text": "A", "start": 74, "end": 75, "id": 14}, {"text": "securely", "start": 76, "end": 84, "id": 15}, {"text": "fixed", "start": 85, "end": 90, "id": 16}, {"text": "acetabular", "start": 91, "end": 101, "id": 17}, {"text": "component", "start": 102, "end": 111, "id": 18}, {"text": "was", "start": 112, "end": 115, "id": 19}, {"text": "confirmed", "start": 116, "end": 125, "id": 20}, {"text": "during", "start": 126, "end": 132, "id": 21}, {"text": "the", "start": 133, "end": 136, "id": 22}, {"text": "revision", "start": 137, "end": 145, "id": 23}, {"text": "surgery", "start": 146, "end": 153, "id": 24}, {"text": ".", "start": 153, "end": 154, "id": 25}, {"text": "Bone", "start": 155, "end": 159, "id": 26}, {"text": "ingrowth", "start": 160, "end": 168, "id": 27}, {"text": "was", "start": 169, "end": 172, "id": 28}, {"text": "shown", "start": 173, "end": 178, "id": 29}, {"text": "within", "start": 179, "end": 185, "id": 30}, {"text": "the", "start": 186, "end": 189, "id": 31}, {"text": "surface", "start": 190, "end": 197, "id": 32}, {"text": "of", "start": 198, "end": 200, "id": 33}, {"text": "acetabular", "start": 201, "end": 211, "id": 34}, {"text": "component", "start": 212, "end": 221, "id": 35}, {"text": "(", "start": 222, "end": 223, "id": 36}, {"text": "a", "start": 223, "end": 224, "id": 37}, {"text": ")", "start": 224, "end": 225, "id": 38}, {"text": ".", "start": 225, "end": 226, "id": 39}, {"text": "b", "start": 227, "end": 228, "id": 40}, {"text": "A", "start": 229, "end": 230, "id": 41}, {"text": "trabecular", "start": 231, "end": 241, "id": 42}, {"text": "metal", "start": 242, "end": 247, "id": 43}, {"text": "acetabular", "start": 248, "end": 258, "id": 44}, {"text": "component", "start": 259, "end": 268, "id": 45}, {"text": "with", "start": 269, "end": 273, "id": 46}, {"text": "decreased", "start": 274, "end": 283, "id": 47}, {"text": "anteversion", "start": 284, "end": 295, "id": 48}, {"text": "was", "start": 296, "end": 299, "id": 49}, {"text": "shown", "start": 300, "end": 305, "id": 50}, {"text": "on", "start": 306, "end": 308, "id": 51}, {"text": "the", "start": 309, "end": 312, "id": 52}, {"text": "radiograph", "start": 313, "end": 323, "id": 53}, {"text": "after", "start": 324, "end": 329, "id": 54}, {"text": "hip", "start": 330, "end": 333, "id": 55}, {"text": "revision", "start": 334, "end": 342, "id": 56}]}
{"pdf_hash": "4797b05b7354020ad8b95da28fe9d1914e795735", "fig_key": "Figure10", "fig_uri": "7-Figure10-1.png", "text": "Figure 10. 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{"pdf_hash": "688e08ad7e5e9348687013556be9bb57425daccf", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 Changes in retinal structure seen in polypoidal choroidal vasculopathy. a Initial fluorescein angiography. b Initial indocyanine green angiography shows numerous polypoidal lesions. c Initial fundus photograph exhibiting reddish-orange nodules and an adjacent detachment of the pigment epithelium. d Fundus photograph at final visit. e Sectional image obtained using optical coherence tomography (OCT) at the initial visit. Numerous hyperreflective foci (yellow arrows), as well as subretinal fluid/fibrin (yellow asterisk) are seen. The fibrin appears to have infiltrated the outer retina but appears to be blocked at the external limiting membrane (white arrowheads). The structure of the neurosensory retina seems to be relatively well-preserved. The line of the external limiting membrane is detectable under the fovea. The visual acuity was 0.3 by the Landolt chart. f Sectional image obtained using OCT at the final visit. 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{"pdf_hash": "8023c0e53d2b10011c174825ccb959e8ecfb85e9", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Contrast-enhanced abdominal computed tomography on the 21st of hospitalization day. Bilateral hydronephrosis (A, B arrows), thickened bladder wal (C, arrows) and thickened ureteral wals (D, arrow) were observed.", "width": 866, "height": 660, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23], "b": [16, 17, 18, 19, 20, 21, 22, 23], "c": [32, 25, 26, 27, 28, 29, 30, 31], "d": [34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "e69c35dc-3622-4ea6-8999-c190919a86c7", "label": "a", "points": [[1.4, 0], [1.4, 288.7], [422.7, 288.7], [422.7, 0]], "color": "yellow"}, {"id": "1dedc0a0-f10c-4609-a573-f540fb48cd9f", "label": "b", "points": [[443.3, 288.7], [443.3, 2.7], [863.3, 2.7], [863.3, 288.7]], "color": "cyan"}, {"id": "3710c009-5149-4242-8a01-9a8acae87474", "label": "c", "points": [[429.6, 365.3], [429.6, 643], [5.5, 643], [5.5, 365.3]], "color": "magenta"}, {"id": "710fda4a-9dd0-43f2-9448-98b98f85905f", "label": "d", "points": [[444.6, 362.5], [444.6, 645.7], [861.9, 645.7], [861.9, 362.5]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Contrast", "start": 10, "end": 18, "id": 3}, {"text": "-", "start": 18, "end": 19, "id": 4}, {"text": "enhanced", "start": 19, "end": 27, "id": 5}, {"text": "abdominal", "start": 28, "end": 37, "id": 6}, {"text": "computed", "start": 38, "end": 46, "id": 7}, {"text": "tomography", "start": 47, "end": 57, "id": 8}, {"text": "on", "start": 58, "end": 60, "id": 9}, {"text": "the", "start": 61, "end": 64, "id": 10}, {"text": "21st", "start": 65, "end": 69, "id": 11}, {"text": "of", "start": 70, "end": 72, "id": 12}, {"text": "hospitalization", "start": 73, "end": 88, "id": 13}, {"text": "day", "start": 89, "end": 92, "id": 14}, {"text": ".", "start": 92, "end": 93, "id": 15}, {"text": "Bilateral", "start": 94, "end": 103, "id": 16}, {"text": "hydronephrosis", "start": 104, "end": 118, "id": 17}, {"text": "(", "start": 119, "end": 120, "id": 18}, {"text": "A", "start": 120, "end": 121, "id": 19}, {"text": ",", "start": 121, "end": 122, "id": 20}, {"text": "B", "start": 123, "end": 124, "id": 21}, {"text": "arrows", "start": 125, "end": 131, "id": 22}, {"text": ")", "start": 131, "end": 132, "id": 23}, {"text": ",", "start": 132, "end": 133, "id": 24}, {"text": "thickened", "start": 134, "end": 143, "id": 25}, {"text": "bladder", "start": 144, "end": 151, "id": 26}, {"text": "wal", "start": 152, "end": 155, "id": 27}, {"text": "(", "start": 156, "end": 157, "id": 28}, {"text": "C", "start": 157, "end": 158, "id": 29}, {"text": ",", "start": 158, "end": 159, "id": 30}, {"text": "arrows", "start": 160, "end": 166, "id": 31}, {"text": ")", "start": 166, "end": 167, "id": 32}, {"text": "and", "start": 168, "end": 171, "id": 33}, {"text": "thickened", "start": 172, "end": 181, "id": 34}, {"text": "ureteral", "start": 182, "end": 190, "id": 35}, {"text": "wals", "start": 191, "end": 195, "id": 36}, {"text": "(", "start": 196, "end": 197, "id": 37}, {"text": "D", "start": 197, "end": 198, "id": 38}, {"text": ",", "start": 198, "end": 199, "id": 39}, {"text": "arrow", "start": 200, "end": 205, "id": 40}, {"text": ")", "start": 205, "end": 206, "id": 41}, {"text": "were", "start": 207, "end": 211, "id": 42}, {"text": "observed", "start": 212, "end": 220, "id": 43}, {"text": ".", "start": 220, "end": 221, "id": 44}]}
{"pdf_hash": "94a03ef5a0bdeaa2af31e54fbf34f30f07b86045", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. The cartilage view on ultrasonography (US), on radiography and during total knee arthroplasty (TKA). On femoral sulcus, axial US-view demonstrates a normal cartilage (white asterisk) without damage (A). On medial femoral condyle, axial parapatellar US-view (patella on the right side, marked as Pat) shows a distinct damage (arrow) on the cartilage (B). The corresponding radiography depicts a clear narrowing (arrow) of the medial joint space (C). Ultimately, the photography of femoral cartilage surfaces taken during the TKA reveals intact femoral sulcus (asterisk) and full-thickness cartilage damage of the medial femoral condyle (arrow) (D).", "width": 900, "height": 900, "subcaptions": {"a": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "b": [45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79], "c": [96, 97, 98, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95], "d": [128, 129, 130, 131, 132, 133, 134, 135, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "17ac8413-34d6-4ba2-824e-850a867602c5", "label": "a", "points": [[7.9, 4], [7.9, 440.5], [440.1, 440.5], [440.1, 4]], "color": "yellow"}, {"id": "f310a213-c1de-4f97-8c6c-894b94c7e267", "label": "b", "points": 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{"pdf_hash": "a4903a3dc636808d786af9c5268b14b8076c96f4", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 - X-ray micro-CT image of molar restored with composite restoration. Note dark region in proximity of gingival margin suggesting gap formation.", "width": 1362, "height": 738, "subcaptions": null, "subfigures": [{"id": "25b6ac78-9294-474b-bbaf-95b7a828d309", "label": "a", "points": [[4.3, 4.3], [4.3, 733.7], [789.7, 733.7], [789.7, 4.3]], "color": "yellow"}, {"id": "c3440fb2-76f4-44ce-a9dd-a29f3bce59f2", "label": "b", "points": [[910.2, 735.9], [910.2, 262.5], [1357.7, 262.5], [1357.7, 735.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "-", "start": 9, "end": 10, "id": 2}, {"text": "X", "start": 11, "end": 12, "id": 3}, {"text": "-", "start": 12, "end": 13, "id": 4}, {"text": "ray", "start": 13, "end": 16, "id": 5}, {"text": "micro", "start": 17, "end": 22, "id": 6}, {"text": "-", "start": 22, "end": 23, "id": 7}, {"text": "CT", "start": 23, "end": 25, "id": 8}, {"text": "image", "start": 26, "end": 31, "id": 9}, {"text": "of", "start": 32, "end": 34, "id": 10}, {"text": "molar", "start": 35, "end": 40, "id": 11}, {"text": "restored", "start": 41, "end": 49, "id": 12}, {"text": "with", "start": 50, "end": 54, "id": 13}, {"text": "composite", "start": 55, "end": 64, "id": 14}, {"text": "restoration", "start": 65, "end": 76, "id": 15}, {"text": ".", "start": 76, "end": 77, "id": 16}, {"text": "Note", "start": 78, "end": 82, "id": 17}, {"text": "dark", "start": 83, "end": 87, "id": 18}, {"text": "region", "start": 88, "end": 94, "id": 19}, {"text": "in", "start": 95, "end": 97, "id": 20}, {"text": "proximity", "start": 98, "end": 107, "id": 21}, {"text": "of", "start": 108, "end": 110, "id": 22}, {"text": "gingival", "start": 111, "end": 119, "id": 23}, {"text": "margin", "start": 120, "end": 126, "id": 24}, {"text": "suggesting", "start": 127, "end": 137, "id": 25}, {"text": "gap", "start": 138, "end": 141, "id": 26}, {"text": "formation", "start": 142, "end": 151, "id": 27}, {"text": ".", "start": 151, "end": 152, "id": 28}]}
{"pdf_hash": "6c6d702087111d2fba836b4dc2f4fdfe00001f9d", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Images of the lumbar spine, pelvis, and the hip. (A) The angle of lumbar lordosis (LL) was measured as an angle between line passing through the superior endplates of L1 and S1 by lateral radiograph of the lumber spine. (B) The pelvic incidence (PI) is defined as the angle between the line perpendicular to the sacral slope at its midpoint and the line connecting this point to the axis of the center of the right and left femoral heads by lateral radiograph of the pelvis. (C) On the mid-sagittal MRI, anterior center-edge (ACE) angle which is made by the intersection plane through the center of the femoral head. 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{"pdf_hash": "a5392abdec2ef40c139cf7ed28202b1e3aeb8f5c", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4 Electron tomography of EPCS and cortical ER. Tomography of EPCS in young roots reveals the complex nature of the ER and its association with the PM. (a) Model overlaid on a slice of the tomographic data to provide context. (b) The modeled cortical cytoplasm with ER shown in green, EPCS are blue, PM is magenta, vesicles are yellow, ribosomes are orange, microtubules are red and plasmodesmata are turquoise. (c) Rotated model to show vesicles interspersed with EPCS. Scale bars represent 200 nm.", "width": 1342, "height": 408, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 31], "b": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83], "c": [84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95]}, "subfigures": [{"id": "5bbbf6bc-e087-4399-a438-ff67f85b5fcc", "label": "a", "points": [[22.3, 8.1], [22.3, 370.7], [446.4, 370.7], [446.4, 8.1]], "color": "yellow"}, {"id": "18dc3707-1d0a-4041-aa77-955483fbc526", "label": "b", "points": [[467.6, 14.5], [467.6, 368.5], [889.5, 368.5], [889.5, 14.5]], "color": "cyan"}, {"id": "54a30aec-0d70-4a76-8550-0007acbc3b0a", "label": "c", "points": [[914.9, 6], [914.9, 374.9], [1334.7, 374.9], [1334.7, 6]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": 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{"pdf_hash": "230113a5c8d55c672f63eb1619e7c3deacc15cc0", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Postoperative CT measurements. Septum pellucidum shift (SPS, \u201cE\u201d) was determined using the distance from the midline to the septum pellucidum at the level of the fornix (A). Pineal gland shift (PGS, \u201cF\u201d) was determined using the distance from the midline to the pineal gland (B). Maximal size of the bone flap (\u201cG\u201d) was measured between opposing hemicraniectomy edges on serial axial slices on the post-hemicraniectomy CT (C). The extracranial bulging volume was measured as the volume of the brain tissue beyond the bony window (areas marked with red lines) and the extracranial bulging ratio was defined as the ratio of the extracranial bulging volume to the maximal size of the bone flap (D).", "width": 1370, "height": 926, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "c": [65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95], "d": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": 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{"pdf_hash": "10f940c108449e7b0ff875084e49031b3aeb3c69", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Pulse infusion thrombolysis and stent placement. The case is an 83-year-old man with a painful, swolen left leg due to extensive DVT diagnosed by computed tomography. A: Venography showed huge thrombus formation in the iliac and femoral veins, with occlusion of the common iliac vein (white arrow). B: PIT was performed with tissue plasminogen activator, monteplase as a thrombolytic agent through the Cragg-McNamara infusion catheter (white arrowhead). C: Venography after PIT demonstrated the stenosis of common iliac vein (black arrow), and stent deployment was performed, D: Venography after Palmaz 9\u00d742 mm stent deployment and expansion to 10 mm diameter with an angioplasty baloon showed a widely patent common iliac vein (black arrowhead).", "width": 1002, "height": 942, "subcaptions": {"a": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59], "b": [60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86], "c": [87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109], "d": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "29afcb3a-565c-4bb2-9b25-07e545b025be", "label": "a", "points": [[36.9, 3], [36.9, 454.1], [483.2, 454.1], [483.2, 3]], "color": 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{"pdf_hash": "e18d8dc5bebbecbd2f6a6737523be71da6f5e8e4", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "FIGURE 5. Iba1 immunohistochemistry showing increased microglial activation in lipopolysaccharidetreated mice. (A) Coronal brain section of mouse injected with saline. (B) Coronal brain sections of mouse injected with lipopolysaccharide after 72 h. (D and E) Respective \u00b720 magnification of insets in A and B. (C) Iba1 staining intensity in saline- vs. lipopolysaccharide-treated mice. (F) Ratio of P2X7R expression level to \u03b2-actin in saline- vs. lipopolysaccharide-treated mice. (G) Western blot of P2X7R protein expression in cortex of lipopolysaccharide-treated mice after 72 h. 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{"pdf_hash": "08119a82b43761685cea5331d0b432c5fc346d9d", "fig_key": "Figure4", "fig_uri": "9-Figure4-1.png", "text": "Fig. 4 Postmortem MRI from non-fixed brains and immunohistochemical staining for APO-E. a postmortem MRI shows only mild white matter hyperintensity in the vicinity of the posterior horn of the lateral ventricle (arrow), b punctate white matter changes in the subcortical white matter (arrow), c severe patchy confluent white matter damage in deep/subcortical white matter at supraventricular level (arrow), d\u2013i Micrographs showing an overview of apoE expression in representative cases in vessel walls, astrocytes and", "width": 1202, "height": 1110, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54], "c": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 55, 56, 57, 58, 59, 60, 61, 62, 63], "d": [75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 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{"pdf_hash": "7ca83a89dc872255e9942bcaddd4b3205b70b7ed", "fig_key": "Figure6", "fig_uri": "11-Figure6-1.png", "text": "Fig 6. Mice are protected from lytic bone lesions using bisphosphonates and osteoprotegerin (m OPG). A) Representative CT Scan images of skulls of MuTuDC injected mice (subcutaneously on the calvaria, close to the left parietal bone). Mice were treated with either PBS (control) or the biphosphonate Aclasta B) Representative stereomicroscopic images of skull bones of mice injected as above with PBS (control) or mOPG one week following adoptive transfer of MuTuDCs. Images in A and B show the absence of bone lesions after Aclasta or mOPG treatments. Arrow indicates the site of MuTuDC injections. Data are from a single experiment representative of two independent experiments. Five mice per group in each experiment. 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{"pdf_hash": "6b1fc2465294238b9667e00cbfb10da0a3cc326e", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Photomicrograph of immunoperoxidase staining of astrocytes infected with VEE or mock-infected. Mock-infected controls show no staining (A). Early time points post-VEE infection (B, 18 h) demonstrate morphologic changes in astrocyte cultures including nuclear condensation and fragmentation (arrows), but no positive staining for VEE. Time points 24 and 48 h (C and D, respectively) reveal positive brown staining for VEE and cytopathic effects to primary astrocyte cultures. 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{"pdf_hash": "51e4bbfc5499d77baeb75a508aa668a30aba1833", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. 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{"pdf_hash": "60bbf69589e36728317202129884d0a217bba8fe", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "FIGURE 1 Planar views of the cephalic region of the embryonic chick sternae. (a) Photographed by transmitted light, unstained sternum dissected from a 17-d embryo, showing the more translucent areas of cartilage. Sternae were divided in half as shown by the solid white line. One half was used for histology. Transverse histological sections were taken from the region shown by the arrow. The region enclosed by the dashed line shows the area of cartilage for tissue culture and collagen synthesis studies. (b) 19-d embryonic chick sternum cleared with the Spalterholtz technique and stained for calcium with alizarin. Note that calcification has occurred directly over the more transparent areas seen in Fig. la. 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{"pdf_hash": "740fc2b24cb3997bbb89def92d3e4bb071fcca1b", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3: 64 year old male with fibromuscular dysplasia. A and B: Sagittal and sagittal oblique images through the left internal carotid artery show a markedly tortuous appearing vessel, with a beaded appearance and focal segments of aneurismal dilatation. Sagittal image through a segment of the left vertebral artery (C), which has a similar appearance, with the vessel appearing tortuous with an irregular beaded contour. 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{"pdf_hash": "00ae69f58ba6f4180b5d82354ba2e3241d74274e", "fig_key": "Figure10", "fig_uri": "7-Figure10-1.png", "text": "Figure 10. First pass perfusion imaging (left) allows bright gadolinium contrast to clearly outline the mass. Delayed contrast 4- chamber view (right) shows heterogeneous enhancement of the mass (see arrows). The internal non-enhancing area likely corresponds with a region of necrosis.", "width": 788, "height": 440, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [32, 33, 34, 35, 36, 37, 38, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "1c4013d7-c5cf-44ed-a344-f14247340089", "label": "a", "points": [[6.6, 4.8], [6.6, 438], [367.6, 438], [367.6, 4.8]], "color": "yellow"}, {"id": "391b25ce-f2e5-4882-8dd8-d030e0bf214e", "label": "b", "points": [[375.1, 6.1], [375.1, 438], [782.1, 438], [782.1, 6.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "10", "start": 7, "end": 9, "id": 1}, {"text": ".", "start": 9, "end": 10, "id": 2}, {"text": "First", "start": 11, "end": 16, "id": 3}, {"text": "pass", "start": 17, "end": 21, "id": 4}, {"text": "perfusion", "start": 22, "end": 31, "id": 5}, {"text": "imaging", "start": 32, "end": 39, "id": 6}, {"text": "(", "start": 40, "end": 41, "id": 7}, {"text": "left", "start": 41, "end": 45, "id": 8}, {"text": ")", "start": 45, "end": 46, "id": 9}, {"text": "allows", "start": 47, "end": 53, "id": 10}, {"text": "bright", "start": 54, "end": 60, "id": 11}, {"text": "gadolinium", "start": 61, "end": 71, "id": 12}, {"text": "contrast", "start": 72, "end": 80, "id": 13}, {"text": "to", "start": 81, "end": 83, "id": 14}, {"text": "clearly", "start": 84, "end": 91, "id": 15}, {"text": "outline", "start": 92, "end": 99, "id": 16}, {"text": "the", "start": 100, "end": 103, "id": 17}, {"text": "mass", "start": 104, "end": 108, "id": 18}, {"text": ".", "start": 108, "end": 109, "id": 19}, {"text": "Delayed", "start": 110, "end": 117, "id": 20}, {"text": "contrast", "start": 118, "end": 126, "id": 21}, {"text": "4-", "start": 127, "end": 129, "id": 22}, {"text": "chamber", "start": 130, "end": 137, "id": 23}, {"text": "view", "start": 138, "end": 142, "id": 24}, {"text": "(", "start": 143, "end": 144, "id": 25}, {"text": "right", "start": 144, "end": 149, "id": 26}, {"text": ")", "start": 149, "end": 150, "id": 27}, {"text": "shows", "start": 151, "end": 156, "id": 28}, {"text": "heterogeneous", "start": 157, "end": 170, "id": 29}, {"text": "enhancement", "start": 171, "end": 182, "id": 30}, {"text": "of", "start": 183, "end": 185, "id": 31}, {"text": "the", "start": 186, "end": 189, "id": 32}, {"text": "mass", "start": 190, "end": 194, "id": 33}, {"text": "(", "start": 195, "end": 196, "id": 34}, {"text": "see", "start": 196, "end": 199, "id": 35}, {"text": "arrows", "start": 200, "end": 206, "id": 36}, {"text": ")", "start": 206, "end": 207, "id": 37}, {"text": ".", "start": 207, "end": 208, "id": 38}, {"text": "The", "start": 209, "end": 212, "id": 39}, {"text": "internal", "start": 213, "end": 221, "id": 40}, {"text": "non", "start": 222, "end": 225, "id": 41}, {"text": "-", "start": 225, "end": 226, "id": 42}, {"text": "enhancing", "start": 226, "end": 235, "id": 43}, {"text": "area", "start": 236, "end": 240, "id": 44}, {"text": "likely", "start": 241, "end": 247, "id": 45}, {"text": "corresponds", "start": 248, "end": 259, "id": 46}, {"text": "with", "start": 260, "end": 264, "id": 47}, {"text": "a", "start": 265, "end": 266, "id": 48}, {"text": "region", "start": 267, "end": 273, "id": 49}, {"text": "of", "start": 274, "end": 276, "id": 50}, {"text": "necrosis", "start": 277, "end": 285, "id": 51}, {"text": ".", "start": 285, "end": 286, "id": 52}]}
{"pdf_hash": "d4e6c97cbb6974e35746c44872f41518d505fb64", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. (A) A preoperative DWI image showed acute infarctions in the left frontal cortex and corona radiata. (B) A postoperative DWI image showed mildly decreased signal intensity at the same infarct area. DWI, diffusionweighted magnetic resonance imaging.", "width": 1010, "height": 596, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "ab6e68a2-3b41-4e7a-b183-c4aca7e8391b", "label": "a", "points": [[4.1, 4.5], [4.1, 591.7], [477.9, 591.7], [477.9, 4.5]], "color": "yellow"}, {"id": "852ad7fb-e2f0-4006-99fe-babe25042a14", "label": "b", "points": [[495.5, 1.3], [495.5, 590.1], [975.7, 590.1], [975.7, 1.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "A", "start": 12, "end": 13, "id": 7}, {"text": "preoperative", "start": 14, "end": 26, "id": 8}, {"text": "DWI", "start": 27, "end": 30, "id": 9}, {"text": "image", "start": 31, "end": 36, "id": 10}, {"text": "showed", "start": 37, "end": 43, "id": 11}, {"text": "acute", "start": 44, "end": 49, "id": 12}, {"text": "infarctions", "start": 50, "end": 61, "id": 13}, {"text": "in", "start": 62, "end": 64, "id": 14}, {"text": "the", "start": 65, "end": 68, "id": 15}, {"text": "left", "start": 69, "end": 73, "id": 16}, {"text": "frontal", "start": 74, "end": 81, "id": 17}, {"text": "cortex", "start": 82, "end": 88, "id": 18}, {"text": "and", "start": 89, "end": 92, "id": 19}, {"text": "corona", "start": 93, "end": 99, "id": 20}, {"text": "radiata", "start": 100, "end": 107, "id": 21}, {"text": ".", "start": 107, "end": 108, "id": 22}, {"text": "(", "start": 109, "end": 110, "id": 23}, {"text": "B", "start": 110, "end": 111, "id": 24}, {"text": ")", "start": 111, "end": 112, "id": 25}, {"text": "A", "start": 113, "end": 114, "id": 26}, {"text": "postoperative", "start": 115, "end": 128, "id": 27}, {"text": "DWI", "start": 129, "end": 132, "id": 28}, {"text": "image", "start": 133, "end": 138, "id": 29}, {"text": "showed", "start": 139, "end": 145, "id": 30}, {"text": "mildly", "start": 146, "end": 152, "id": 31}, {"text": "decreased", "start": 153, "end": 162, "id": 32}, {"text": "signal", "start": 163, "end": 169, "id": 33}, {"text": "intensity", "start": 170, "end": 179, "id": 34}, {"text": "at", "start": 180, "end": 182, "id": 35}, {"text": "the", "start": 183, "end": 186, "id": 36}, {"text": "same", "start": 187, "end": 191, "id": 37}, {"text": "infarct", "start": 192, "end": 199, "id": 38}, {"text": "area", "start": 200, "end": 204, "id": 39}, {"text": ".", "start": 204, "end": 205, "id": 40}, {"text": "DWI", "start": 206, "end": 209, "id": 41}, {"text": ",", "start": 209, "end": 210, "id": 42}, {"text": "diffusionweighted", "start": 211, "end": 228, "id": 43}, {"text": "magnetic", "start": 229, "end": 237, "id": 44}, {"text": "resonance", "start": 238, "end": 247, "id": 45}, {"text": "imaging", "start": 248, "end": 255, "id": 46}, {"text": ".", "start": 255, "end": 256, "id": 47}]}
{"pdf_hash": "920622f4402891874af771625c66363dbd4a26ba", "fig_key": "Figure9", "fig_uri": "11-Figure9-1.png", "text": "Fig. 9 A 15-year-old girl with osteosarcoma of the right distal femur presented with new widespread metastases to bones, soft tissues and lungs, prompting a search for an intracardiac source. a Axial noncontrast and (b) contrast-enhanced chest CT images show subtle mineralized myocardial metastasis (arrows) within the interventricular septum. c Myocardial enhancement phase image from an fast gradient recalled echo first pass perfusion sequence in the four-chamber view shows enhancement of the metastasis around the calcium-related signal void (arrow). The girl had similar metastasis along the left ventricular free wall (not shown). The two intracardiac metastases were resected and proved to be metastatic osteosarcoma. 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{"pdf_hash": "bbbb780d6ea78fa852e855b4016ea6e0601a1584", "fig_key": "Figure2", "fig_uri": "34-Figure2-1.png", "text": "Fig. 2. (a) X-ray micro CT (\u00b5CT) images of bone formation within the region of interest (ROI). Bone ingrowth was quantified at (b,c) 2, (d,e) 6 and (f,g) 12 weeks post-operation. Arrows indicate the newly regenerated bone in the uncoated (green) and silver coated group (red). (h) The amount of bone ingrowth, expressed as the percentage bone volume within ROI as measured by \u00b5CT. Statistical significance (*) was considered where p < 0.05. 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{"pdf_hash": "f8c031823573c7d1d1329e13a2225475814d0a12", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. Left picture indicates that oblique magnetic resonance imaging section bisecting the exiting root (yellow dot) and the facet joint (green interrupted boundary) taken at the level of lower end plate level as seen on sagittal view. Right picture indicates that the sides of this triangle (yellow border) are bound by the exiting nerve root (the hypotenuse), the facet i.e., superior articular process of inferior vertebra (the vertical limb) and the lower end plate level (the base). Red circle in the right picture represents the cannula within the bony Kambin\u2019s triangle. 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{"pdf_hash": "e6c12c07e154fbfa2d105dfb0777facfa669fe0a", "fig_key": "Figure14", "fig_uri": "18-Figure14-1.png", "text": "Figure 14. (a) Tomography of a Ti-based porous dental implant for osseointegration improvement; and (b) detail of the inner structure and porous surface (courtesy of Louis-Philippe Lefebvre).", "width": 1194, "height": 344, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "794df500-dfd5-42ad-b9fa-22b10e5af96a", "label": "e", "points": [[1.9, 0], [1.9, 305.6], [822.5, 305.6], [822.5, 0]], "color": "yellow"}, {"id": "76363536-83ce-4e09-a8b4-121d5f2d82c4", "label": "b", "points": [[864, 309.4], [864, 5.7], [1192.2, 5.7], [1192.2, 309.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "14", "start": 7, "end": 9, "id": 1}, {"text": ".", "start": 9, "end": 10, "id": 2}, {"text": "(", "start": 11, "end": 12, "id": 3}, {"text": "a", "start": 12, "end": 13, "id": 4}, {"text": ")", "start": 13, "end": 14, "id": 5}, {"text": "Tomography", "start": 15, "end": 25, "id": 6}, {"text": "of", "start": 26, "end": 28, "id": 7}, {"text": "a", "start": 29, "end": 30, "id": 8}, {"text": "Ti", "start": 31, "end": 33, "id": 9}, {"text": "-", "start": 33, "end": 34, "id": 10}, {"text": "based", "start": 34, "end": 39, "id": 11}, {"text": "porous", "start": 40, "end": 46, "id": 12}, {"text": "dental", "start": 47, "end": 53, "id": 13}, {"text": "implant", "start": 54, "end": 61, "id": 14}, {"text": "for", "start": 62, "end": 65, "id": 15}, {"text": "osseointegration", "start": 66, "end": 82, "id": 16}, {"text": "improvement", "start": 83, "end": 94, "id": 17}, {"text": ";", "start": 94, "end": 95, "id": 18}, {"text": "and", "start": 96, "end": 99, "id": 19}, {"text": "(", "start": 100, "end": 101, "id": 20}, {"text": "b", "start": 101, "end": 102, "id": 21}, {"text": ")", "start": 102, "end": 103, "id": 22}, {"text": "detail", "start": 104, "end": 110, "id": 23}, {"text": "of", "start": 111, "end": 113, "id": 24}, {"text": "the", "start": 114, "end": 117, "id": 25}, {"text": "inner", "start": 118, "end": 123, "id": 26}, {"text": "structure", "start": 124, "end": 133, "id": 27}, {"text": "and", "start": 134, "end": 137, "id": 28}, {"text": "porous", "start": 138, "end": 144, "id": 29}, {"text": "surface", "start": 145, "end": 152, "id": 30}, {"text": "(", "start": 153, "end": 154, "id": 31}, {"text": "courtesy", "start": 154, "end": 162, "id": 32}, {"text": "of", "start": 163, "end": 165, "id": 33}, {"text": "Louis", "start": 166, "end": 171, "id": 34}, {"text": "-", "start": 171, "end": 172, "id": 35}, {"text": "Philippe", "start": 172, "end": 180, "id": 36}, {"text": "Lefebvre", "start": 181, "end": 189, "id": 37}, {"text": ")", "start": 189, "end": 190, "id": 38}, {"text": ".", "start": 190, "end": 191, "id": 39}]}
{"pdf_hash": "ecd503fc03ec104d110d2a7cf6fbdaa602768e00", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Fig. 6. (A) Dystopic os odontoideum with the odontoid fragment fused to the basion. (B, C) Sagittal and coronal images show orthotopic os odontoideum with round margins and wider clear space between the ossicle and axis to be differentiated from nonunion odontoid (D, E).", "width": 638, "height": 472, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "c": [19, 20, 21, 22, 23, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "d": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "e": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "6dbaa1a8-ae52-4ebc-a025-9fc9b163f4b9", "label": "a", "points": [[1, 1], [1, 243.9], [200.6, 243.9], [200.6, 1]], "color": "yellow"}, {"id": "1dd445ca-9fe9-4c2a-8f61-21fe35163757", "label": "b", "points": [[211.7, 2], [211.7, 241.9], [437.4, 241.9], [437.4, 2]], "color": "cyan"}, {"id": "7b74e449-1a1c-4389-ab47-591a3a5b67bf", "label": "c", "points": [[445.5, 243.9], [445.5, 0], [635, 0], [635, 243.9]], "color": "magenta"}, {"id": "ead7bf65-24b4-45a5-93cb-0a26d65ce055", "label": "d", "points": [[200.6, 445.5], [200.6, 253], [1, 253], [1, 445.5]], "color": "springgreen"}, {"id": "0bd3916c-a436-4445-87f4-aa21fe5370e4", "label": "e", "points": [[207.6, 253], [207.6, 449.5], [458.6, 449.5], [458.6, 253]], "color": "tomato"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "6", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Dystopic", "start": 12, "end": 20, "id": 7}, {"text": "os", "start": 21, "end": 23, "id": 8}, {"text": "odontoideum", "start": 24, "end": 35, "id": 9}, {"text": "with", "start": 36, "end": 40, "id": 10}, {"text": "the", "start": 41, "end": 44, "id": 11}, {"text": "odontoid", "start": 45, "end": 53, "id": 12}, {"text": "fragment", "start": 54, "end": 62, "id": 13}, {"text": "fused", "start": 63, "end": 68, "id": 14}, {"text": "to", "start": 69, "end": 71, "id": 15}, {"text": "the", "start": 72, "end": 75, "id": 16}, {"text": "basion", "start": 76, "end": 82, "id": 17}, {"text": ".", "start": 82, "end": 83, "id": 18}, {"text": "(", "start": 84, "end": 85, "id": 19}, {"text": "B", "start": 85, "end": 86, "id": 20}, {"text": ",", "start": 86, "end": 87, "id": 21}, {"text": "C", "start": 88, "end": 89, "id": 22}, {"text": ")", "start": 89, "end": 90, "id": 23}, {"text": "Sagittal", "start": 91, "end": 99, "id": 24}, {"text": "and", "start": 100, "end": 103, "id": 25}, {"text": "coronal", "start": 104, "end": 111, "id": 26}, {"text": "images", "start": 112, "end": 118, "id": 27}, {"text": "show", "start": 119, "end": 123, "id": 28}, {"text": "orthotopic", "start": 124, "end": 134, "id": 29}, {"text": "os", "start": 135, "end": 137, "id": 30}, {"text": "odontoideum", "start": 138, "end": 149, "id": 31}, {"text": "with", "start": 150, "end": 154, "id": 32}, {"text": "round", "start": 155, "end": 160, "id": 33}, {"text": "margins", "start": 161, "end": 168, "id": 34}, {"text": "and", "start": 169, "end": 172, "id": 35}, {"text": "wider", "start": 173, "end": 178, "id": 36}, {"text": "clear", "start": 179, "end": 184, "id": 37}, {"text": "space", "start": 185, "end": 190, "id": 38}, {"text": "between", "start": 191, "end": 198, "id": 39}, {"text": "the", "start": 199, "end": 202, "id": 40}, {"text": "ossicle", "start": 203, "end": 210, "id": 41}, {"text": "and", "start": 211, "end": 214, "id": 42}, {"text": "axis", "start": 215, "end": 219, "id": 43}, {"text": "to", "start": 220, "end": 222, "id": 44}, {"text": "be", "start": 223, "end": 225, "id": 45}, {"text": "differentiated", "start": 226, "end": 240, "id": 46}, {"text": "from", "start": 241, "end": 245, "id": 47}, {"text": "nonunion", "start": 246, "end": 254, "id": 48}, {"text": "odontoid", "start": 255, "end": 263, "id": 49}, {"text": "(", "start": 264, "end": 265, "id": 50}, {"text": "D", "start": 265, "end": 266, "id": 51}, {"text": ",", "start": 266, "end": 267, "id": 52}, {"text": "E", "start": 268, "end": 269, "id": 53}, {"text": ")", "start": 269, "end": 270, "id": 54}, {"text": ".", "start": 270, "end": 271, "id": 55}]}
{"pdf_hash": "c825b3c7555051954621162b8ff3db1c3072bead", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 (a) T2W left parasagittal image of the cervical spine in Patient 1 showing the site of injury (arrow head); (b) Mid-sagittal T2W image showing intramedullary hyperintensity between C4\u2013C6 (injury zone). The segments of the cord demarcated by the dotted line were selected for tractography; (c) Axial T2W image at the injury site showing ill-defined hyperintensity within the left hemicord. Block arrow shows the direction of injury; (d) Axial FA map at the injury site showing obliteration of the cord structure (solid line) particularly within the left hemicord (block arrow) (A\u2014anterior, P\u2014posterior); (e) Anterior view of fiber tracts around the site of injury (arrow head) shows disrupted white matter tracts and low anisotropic fibers on the left half of the cord (color bar represents mean anisotropy) (R\u2014right, L\u2014left). 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{"pdf_hash": "7e536554882d0bbdbd9fc49ee6f4a2d10c2d9dde", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. (A) Two-dimensional ultrasound image and (B) contrast-enhanced voiding urosonography images of the kidney in which the left side exhibits complication with hydronephrosis. A contrast agent was present in the upper collecting system (arrow head) and an expanded tortuous ureter was observed (arrow). 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{"pdf_hash": "d15d34733ae626a42a134939f7bce7d2a6d87e47", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Lateral cephalometric radiograph (a) and dental pantomogram (b) of a patient, with a palatally displaced canine. The sella turcica is partially calcifi ed.", "width": 630, "height": 894, "subcaptions": {"a": [2, 3, 4, 5, 6, 7], "b": [9, 10, 11, 12, 13]}, "subfigures": [{"id": "5cc20b23-e4e2-4f58-bd4b-c7560e6ae21f", "label": "a", "points": [[3.8, 1.9], [3.8, 523.9], [627.8, 523.9], [627.8, 1.9]], "color": "yellow"}, {"id": "7b94d3c6-bcbe-4ad3-a6bc-bf5256929dd8", "label": "b", "points": [[5.8, 545.4], [5.8, 891.4], [624.8, 891.4], [624.8, 545.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Lateral", "start": 9, "end": 16, "id": 2}, {"text": "cephalometric", "start": 17, "end": 30, "id": 3}, {"text": "radiograph", "start": 31, "end": 41, "id": 4}, {"text": "(", "start": 42, "end": 43, "id": 5}, {"text": "a", "start": 43, "end": 44, "id": 6}, {"text": ")", "start": 44, "end": 45, "id": 7}, {"text": "and", "start": 46, "end": 49, "id": 8}, {"text": "dental", "start": 50, "end": 56, "id": 9}, {"text": "pantomogram", "start": 57, "end": 68, "id": 10}, {"text": "(", "start": 69, "end": 70, "id": 11}, {"text": "b", "start": 70, "end": 71, "id": 12}, {"text": ")", "start": 71, "end": 72, "id": 13}, {"text": "of", "start": 73, "end": 75, "id": 14}, {"text": "a", "start": 76, "end": 77, "id": 15}, {"text": "patient", "start": 78, "end": 85, "id": 16}, {"text": ",", "start": 85, "end": 86, "id": 17}, {"text": "with", "start": 87, "end": 91, "id": 18}, {"text": "a", "start": 92, "end": 93, "id": 19}, {"text": "palatally", "start": 94, "end": 103, "id": 20}, {"text": "displaced", "start": 104, "end": 113, "id": 21}, {"text": "canine", "start": 114, "end": 120, "id": 22}, {"text": ".", "start": 120, "end": 121, "id": 23}, {"text": "The", "start": 122, "end": 125, "id": 24}, {"text": "sella", "start": 126, "end": 131, "id": 25}, {"text": "turcica", "start": 132, "end": 139, "id": 26}, {"text": "is", "start": 140, "end": 142, "id": 27}, {"text": "partially", "start": 143, "end": 152, "id": 28}, {"text": "calcifi", "start": 153, "end": 160, "id": 29}, {"text": "ed", "start": 161, "end": 163, "id": 30}, {"text": ".", "start": 163, "end": 164, "id": 31}]}
{"pdf_hash": "5b647a57077c7cf546051ba8741b147b757c89d2", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3 | Synchrotron hard X-ray nano-tomography of surface new phase. (a,b) FIB milling process at the surface of C/LiFePO4 ingot sample. (c) The 3D morphology of the FIB sample. (d) The 2D chemical mapping of selected zone (white dashed box) at the FIB sample. (e) Fe K-edge of XANES profile of selected points in d. 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{"pdf_hash": "4b10c379f09e1857cacf36ff3e2be1aeed0fd295", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 99mTc-DTPA-galactosyl human serum albumin (GSA) liver scintigraphy showed normal accumulation of GSA in non-neoplastic lesion (a). Each gadolinium-ethoxybenzyl-diethylene triamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) showed pre-contrast T1-weighted image (b), arterial dominant phase (c), portaldominant phase (d), transitional phase (e), and hepatobiliary phase (f). Hepatobiliary phase showed slight enhance with poor contrast enhancement to spleen or vessels in non-neoplastic site", "width": 1014, "height": 676, "subcaptions": {"c": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 61, 62, 63, 64, 65, 66], "a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "d": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 68, 69, 70, 71, 72], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59], "f": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 81, 82, 83, 84, 85], "e": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 74, 75, 76, 77, 78]}, "subfigures": [{"id": "48998fc2-4c6e-4d2a-860f-e2868b3cc19f", "label": "a", "points": [[6.4, 16], [6.4, 640.8], [413.3, 640.8], [413.3, 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{"pdf_hash": "a614c88f8389ac90d94cfd6e247531713e526064", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. MRI T2-weighted images showing hyperintensities (arrows) in the brainstem and spinal cord. A: Brainstem, sagittal view. B: Brainstem, axial view. C: Spinal cord, sagittal view.", "width": 1342, "height": 520, "subcaptions": {"a": [19, 20, 21, 22, 23, 24], "b": [26, 27, 28, 29, 30, 31, 32], "c": [33, 34, 35, 36, 37, 38, 39, 40]}, "subfigures": [{"id": "940b8f8f-b856-44a6-b91d-75c0e2068520", "label": "a", "points": [[0, 8.5], [0, 494], [464.3, 494], [464.3, 8.5]], "color": "yellow"}, {"id": "cc1b9a7c-00e0-4af3-86a5-2da0fa942d88", "label": "b", "points": [[477, 2.1], [477, 496.1], [949.8, 496.1], [949.8, 2.1]], "color": "cyan"}, {"id": "5d3855b2-541b-4a66-9646-86d82b43315f", "label": "c", "points": [[960.4, 6.4], [960.4, 491.9], [1335.7, 491.9], [1335.7, 6.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "MRI", "start": 8, "end": 11, "id": 4}, {"text": "T2-weighted", "start": 12, "end": 23, "id": 5}, {"text": "images", "start": 24, "end": 30, "id": 6}, {"text": "showing", "start": 31, "end": 38, "id": 7}, {"text": "hyperintensities", "start": 39, "end": 55, "id": 8}, {"text": "(", "start": 56, "end": 57, "id": 9}, {"text": "arrows", "start": 57, "end": 63, "id": 10}, {"text": ")", "start": 63, "end": 64, "id": 11}, {"text": "in", "start": 65, "end": 67, "id": 12}, {"text": "the", "start": 68, "end": 71, "id": 13}, {"text": "brainstem", "start": 72, "end": 81, "id": 14}, {"text": "and", "start": 82, "end": 85, "id": 15}, {"text": "spinal", "start": 86, "end": 92, "id": 16}, {"text": "cord", "start": 93, "end": 97, "id": 17}, {"text": ".", "start": 97, "end": 98, "id": 18}, {"text": "A", "start": 99, "end": 100, "id": 19}, {"text": ":", "start": 100, "end": 101, "id": 20}, {"text": "Brainstem", "start": 102, "end": 111, "id": 21}, {"text": ",", "start": 111, "end": 112, "id": 22}, {"text": "sagittal", "start": 113, "end": 121, "id": 23}, {"text": "view", "start": 122, "end": 126, "id": 24}, {"text": ".", "start": 126, "end": 127, "id": 25}, {"text": "B", "start": 128, "end": 129, "id": 26}, {"text": ":", "start": 129, "end": 130, "id": 27}, {"text": "Brainstem", "start": 131, "end": 140, "id": 28}, {"text": ",", "start": 140, "end": 141, "id": 29}, {"text": "axial", "start": 142, "end": 147, "id": 30}, {"text": "view", "start": 148, "end": 152, "id": 31}, {"text": ".", "start": 152, "end": 153, "id": 32}, {"text": "C", "start": 154, "end": 155, "id": 33}, {"text": ":", "start": 155, "end": 156, "id": 34}, {"text": "Spinal", "start": 157, "end": 163, "id": 35}, {"text": "cord", "start": 164, "end": 168, "id": 36}, {"text": ",", "start": 168, "end": 169, "id": 37}, {"text": "sagittal", "start": 170, "end": 178, "id": 38}, {"text": "view", "start": 179, "end": 183, "id": 39}, {"text": ".", "start": 183, "end": 184, "id": 40}]}
{"pdf_hash": "c96757556bc64cc80ac3b5e262bef22c38b79920", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Abdominal CT. A) Plain abdominal CT on the first hospital day. B) Enhanced abdominal CT on the 8th hospital day. C) Crescent-shaped enhanced area (arrows).", "width": 1384, "height": 846, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "c": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "73c1bea4-9326-41cf-a266-ae83146afb37", "label": "a", "points": [[9.9, 8.4], [9.9, 430.3], [659.3, 430.3], [659.3, 8.4]], "color": "yellow"}, {"id": "bda4cf53-30d8-4990-8bea-a1a069b7066a", "label": "b", "points": [[700.8, 4], [700.8, 382.2], [1354.5, 382.2], [1354.5, 4]], "color": "cyan"}, {"id": "5a9ac3c9-8f2d-4ee3-9bbd-281d0e93c88c", "label": "c", "points": [[7.7, 456.6], [7.7, 841.4], [657.1, 841.4], [657.1, 456.6]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Abdominal", "start": 10, "end": 19, "id": 3}, {"text": "CT", "start": 20, "end": 22, "id": 4}, {"text": ".", "start": 22, "end": 23, "id": 5}, {"text": "A", "start": 24, "end": 25, "id": 6}, {"text": ")", "start": 25, "end": 26, "id": 7}, {"text": "Plain", "start": 27, "end": 32, "id": 8}, {"text": "abdominal", "start": 33, "end": 42, "id": 9}, {"text": "CT", "start": 43, "end": 45, "id": 10}, {"text": "on", "start": 46, "end": 48, "id": 11}, {"text": "the", "start": 49, "end": 52, "id": 12}, {"text": "first", "start": 53, "end": 58, "id": 13}, {"text": "hospital", "start": 59, "end": 67, "id": 14}, {"text": "day", "start": 68, "end": 71, "id": 15}, {"text": ".", "start": 71, "end": 72, "id": 16}, {"text": "B", "start": 73, "end": 74, "id": 17}, {"text": ")", "start": 74, "end": 75, "id": 18}, {"text": "Enhanced", "start": 76, "end": 84, "id": 19}, {"text": "abdominal", "start": 85, "end": 94, "id": 20}, {"text": "CT", "start": 95, "end": 97, "id": 21}, {"text": "on", "start": 98, "end": 100, "id": 22}, {"text": "the", "start": 101, "end": 104, "id": 23}, {"text": "8th", "start": 105, "end": 108, "id": 24}, {"text": "hospital", "start": 109, "end": 117, "id": 25}, {"text": "day", "start": 118, "end": 121, "id": 26}, {"text": ".", "start": 121, "end": 122, "id": 27}, {"text": "C", "start": 123, "end": 124, "id": 28}, {"text": ")", "start": 124, "end": 125, "id": 29}, {"text": "Crescent", "start": 126, "end": 134, "id": 30}, {"text": "-", "start": 134, "end": 135, "id": 31}, {"text": "shaped", "start": 135, "end": 141, "id": 32}, {"text": "enhanced", "start": 142, "end": 150, "id": 33}, {"text": "area", "start": 151, "end": 155, "id": 34}, {"text": "(", "start": 156, "end": 157, "id": 35}, {"text": "arrows", "start": 157, "end": 163, "id": 36}, {"text": ")", "start": 163, "end": 164, "id": 37}, {"text": ".", "start": 164, "end": 165, "id": 38}]}
{"pdf_hash": "3a34effdc8a95eb3548c67d01f9cc2ad106eae20", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Fig. 4 Case 3 with typical SBT. 25-year-old woman with left ovarian typical SBT. Axial T2WI (a) shows a left ovarian cystic mass with intracystic mural nodules. The largest papillary nodule (arrows) demonstrates inhomogeneous slight hyperintensity in the internal portion and hyperintensity equal to SI of cystic content in the external portion. The normal right ovary is present (arrowheads). After administration of gadolinium DTPA, the mural nodules are enhanced and the conspicuity is increased (b). On DWI, the internal portion of the largest papillary nodule shows hyperintensity equal to the SI of uterine endometrium (arrowhead) but the external portion (arrows) shows less signal intensity. c A photomicrograph of the area corresponding to the largest papillary nodule (d) shows that foci with densely branched papillae with little space among papillae are frequently found in the internal portion (arrows), corresponding to inhomogeneous slight hyperintensity on T2WI. In contrast, a loose papillary architecture of peripheral vegetation with edema (arrowheads) tends to be observed in the external portion, corresponding to hyperintensity on T2WI", "width": 856, "height": 1364, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72], "b": [73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92], "c": [128, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "d": [129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 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{"pdf_hash": "f6bf2d4c54a725feb5b249b75d6ec3dfe1a37d07", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Sagittal section of skin\u2013muscle tissue taken from the scapular region of a rat (body weight ca. 200 g) showing, from top to bottom, a epidermis, b dermis, c skin (panniculus) muscle, d subcutaneous connective tissue, and e skeletal muscle of trunk. Hematoxylin-eosin staining. Bar=0.5 mm", "width": 664, "height": 528, "subcaptions": {"a": [34, 35], "b": [37, 38, 39], "c": [40, 41, 42, 43, 44, 45], "d": [47, 48, 49, 50, 51], "e": [53, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "0dc698f2-91b8-4f71-860f-7f65862f0a8b", "label": "a", "points": [[5.5, 32.4], [5.5, 123.6], [662.2, 123.6], [662.2, 32.4]], "color": "yellow"}, {"id": "d619d525-546e-4fdb-b666-11a465920867", "label": "b", "points": [[5.5, 126.8], [5.5, 222.2], [660.1, 222.2], [660.1, 126.8]], "color": "cyan"}, {"id": "f10d2167-aa10-4a39-a985-ba9aaa791b0b", "label": "c", "points": [[4.5, 228.5], [4.5, 300.9], [659, 300.9], [659, 228.5]], "color": "magenta"}, {"id": "da6352fa-fd49-4639-bb14-71385fca1de8", "label": "d", "points": [[7.6, 310.3], [7.6, 373.3], [660.1, 373.3], [660.1, 310.3]], "color": "springgreen"}, {"id": "6b1ec946-ced4-4f4b-93a0-bca5f14faec4", "label": "e", "points": [[8.7, 379.6], [8.7, 501.3], [660.1, 501.3], [660.1, 379.6]], "color": "tomato"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Sagittal", "start": 8, "end": 16, "id": 4}, {"text": "section", "start": 17, "end": 24, "id": 5}, {"text": "of", "start": 25, "end": 27, "id": 6}, {"text": "skin", "start": 28, "end": 32, "id": 7}, {"text": "\u2013", "start": 32, "end": 33, "id": 8}, {"text": "muscle", "start": 33, "end": 39, "id": 9}, {"text": "tissue", "start": 40, "end": 46, "id": 10}, {"text": "taken", "start": 47, "end": 52, "id": 11}, {"text": "from", "start": 53, "end": 57, "id": 12}, {"text": "the", "start": 58, "end": 61, "id": 13}, {"text": "scapular", "start": 62, "end": 70, "id": 14}, {"text": "region", "start": 71, "end": 77, "id": 15}, {"text": "of", "start": 78, "end": 80, "id": 16}, {"text": "a", "start": 81, "end": 82, "id": 17}, {"text": "rat", "start": 83, "end": 86, "id": 18}, {"text": "(", "start": 87, "end": 88, "id": 19}, {"text": "body", "start": 88, "end": 92, "id": 20}, {"text": "weight", "start": 93, "end": 99, "id": 21}, {"text": "ca", "start": 100, "end": 102, "id": 22}, {"text": ".", "start": 102, "end": 103, "id": 23}, {"text": "200", "start": 104, "end": 107, "id": 24}, {"text": "g", "start": 108, "end": 109, "id": 25}, {"text": ")", "start": 109, "end": 110, "id": 26}, {"text": "showing", "start": 111, "end": 118, "id": 27}, {"text": ",", "start": 118, "end": 119, "id": 28}, {"text": "from", "start": 120, "end": 124, "id": 29}, {"text": "top", "start": 125, "end": 128, "id": 30}, {"text": "to", "start": 129, "end": 131, "id": 31}, {"text": "bottom", "start": 132, "end": 138, "id": 32}, {"text": ",", "start": 138, "end": 139, "id": 33}, {"text": "a", "start": 140, "end": 141, "id": 34}, {"text": "epidermis", "start": 142, "end": 151, "id": 35}, {"text": ",", "start": 151, "end": 152, "id": 36}, {"text": "b", "start": 153, "end": 154, "id": 37}, {"text": "dermis", "start": 155, "end": 161, "id": 38}, {"text": ",", "start": 161, "end": 162, "id": 39}, {"text": "c", "start": 163, "end": 164, "id": 40}, {"text": "skin", "start": 165, "end": 169, "id": 41}, {"text": "(", "start": 170, "end": 171, "id": 42}, {"text": "panniculus", "start": 171, "end": 181, "id": 43}, {"text": ")", "start": 181, "end": 182, "id": 44}, {"text": "muscle", "start": 183, "end": 189, "id": 45}, {"text": ",", "start": 189, "end": 190, "id": 46}, {"text": "d", "start": 191, "end": 192, "id": 47}, {"text": "subcutaneous", "start": 193, "end": 205, "id": 48}, {"text": "connective", "start": 206, "end": 216, "id": 49}, {"text": "tissue", "start": 217, "end": 223, "id": 50}, {"text": ",", "start": 223, "end": 224, "id": 51}, {"text": "and", "start": 225, "end": 228, "id": 52}, {"text": "e", "start": 229, "end": 230, "id": 53}, {"text": "skeletal", "start": 231, "end": 239, "id": 54}, {"text": "muscle", "start": 240, "end": 246, "id": 55}, {"text": "of", "start": 247, "end": 249, "id": 56}, {"text": "trunk", "start": 250, "end": 255, "id": 57}, {"text": ".", "start": 255, "end": 256, "id": 58}, {"text": "Hematoxylin", "start": 257, "end": 268, "id": 59}, {"text": "-", "start": 268, "end": 269, "id": 60}, {"text": "eosin", "start": 269, "end": 274, "id": 61}, {"text": "staining", "start": 275, "end": 283, "id": 62}, {"text": ".", "start": 283, "end": 284, "id": 63}, {"text": "Bar=0.5", "start": 285, "end": 292, "id": 64}, {"text": "mm", "start": 293, "end": 295, "id": 65}]}
{"pdf_hash": "208ba34cfcf710d2b40b41f8dfd928638331c736", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3A\u2013C (A) A loose and dislocated glenoid component has resulted in massive glenoid bone loss in this failed total shoulder arthroplasty (Patient 9). (B) An initial postoperative radiograph shows the structural allograft has been fixed into the glenoid defect. (C) A 2- year postoperative radiograph shows substantial subsidence of the graft and uncovering of the screws.", "width": 1040, "height": 356, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "c": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70]}, "subfigures": [{"id": "8665d575-1a9b-4cf9-b24e-0748407cfaa2", "label": "a", "points": [[14, 6.3], [14, 320.1], [347.6, 320.1], [347.6, 6.3]], "color": "yellow"}, {"id": "fc31ee9a-a8d1-4a60-9759-fb6690b920b2", "label": "b", "points": [[360.7, 1.4], [360.7, 318.5], [684.4, 318.5], [684.4, 1.4]], "color": "cyan"}, {"id": "2ea8ec28-f6f0-4cd4-85f4-46e869fd2699", "label": "c", "points": [[700.8, 3], [700.8, 323.4], [1006.4, 323.4], [1006.4, 3]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3A", "start": 5, "end": 7, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "C", "start": 8, "end": 9, "id": 4}, {"text": "(", "start": 10, "end": 11, "id": 5}, {"text": "A", "start": 11, "end": 12, "id": 6}, {"text": ")", "start": 12, "end": 13, "id": 7}, {"text": "A", "start": 14, "end": 15, "id": 8}, {"text": "loose", "start": 16, "end": 21, "id": 9}, {"text": "and", "start": 22, "end": 25, "id": 10}, {"text": "dislocated", "start": 26, "end": 36, "id": 11}, {"text": "glenoid", "start": 37, "end": 44, "id": 12}, {"text": "component", "start": 45, "end": 54, "id": 13}, {"text": "has", "start": 55, "end": 58, "id": 14}, {"text": "resulted", "start": 59, "end": 67, "id": 15}, {"text": "in", "start": 68, "end": 70, "id": 16}, {"text": "massive", "start": 71, "end": 78, "id": 17}, {"text": "glenoid", "start": 79, "end": 86, "id": 18}, {"text": "bone", "start": 87, "end": 91, "id": 19}, {"text": "loss", "start": 92, "end": 96, "id": 20}, {"text": "in", "start": 97, "end": 99, "id": 21}, {"text": "this", "start": 100, "end": 104, "id": 22}, {"text": "failed", "start": 105, "end": 111, "id": 23}, {"text": "total", "start": 112, "end": 117, "id": 24}, {"text": "shoulder", "start": 118, "end": 126, "id": 25}, {"text": "arthroplasty", "start": 127, "end": 139, "id": 26}, {"text": "(", "start": 140, "end": 141, "id": 27}, {"text": "Patient", "start": 141, "end": 148, "id": 28}, {"text": "9", "start": 149, "end": 150, "id": 29}, {"text": ")", "start": 150, "end": 151, "id": 30}, {"text": ".", "start": 151, "end": 152, "id": 31}, {"text": "(", "start": 153, "end": 154, "id": 32}, {"text": "B", "start": 154, "end": 155, "id": 33}, {"text": ")", "start": 155, "end": 156, "id": 34}, {"text": "An", "start": 157, "end": 159, "id": 35}, {"text": "initial", "start": 160, "end": 167, "id": 36}, {"text": "postoperative", "start": 168, "end": 181, "id": 37}, {"text": "radiograph", "start": 182, "end": 192, "id": 38}, {"text": "shows", "start": 193, "end": 198, "id": 39}, {"text": "the", "start": 199, "end": 202, "id": 40}, {"text": "structural", "start": 203, "end": 213, "id": 41}, {"text": "allograft", "start": 214, "end": 223, "id": 42}, {"text": "has", "start": 224, "end": 227, "id": 43}, {"text": "been", "start": 228, "end": 232, "id": 44}, {"text": "fixed", "start": 233, "end": 238, "id": 45}, {"text": "into", "start": 239, "end": 243, "id": 46}, {"text": "the", "start": 244, "end": 247, "id": 47}, {"text": "glenoid", "start": 248, "end": 255, "id": 48}, {"text": "defect", "start": 256, "end": 262, "id": 49}, {"text": ".", "start": 262, "end": 263, "id": 50}, {"text": "(", "start": 264, "end": 265, "id": 51}, {"text": "C", "start": 265, "end": 266, "id": 52}, {"text": ")", "start": 266, "end": 267, "id": 53}, {"text": "A", "start": 268, "end": 269, "id": 54}, {"text": "2-", "start": 270, "end": 272, "id": 55}, {"text": "year", "start": 273, "end": 277, "id": 56}, {"text": "postoperative", "start": 278, "end": 291, "id": 57}, {"text": "radiograph", "start": 292, "end": 302, "id": 58}, {"text": "shows", "start": 303, "end": 308, "id": 59}, {"text": "substantial", "start": 309, "end": 320, "id": 60}, {"text": "subsidence", "start": 321, "end": 331, "id": 61}, {"text": "of", "start": 332, "end": 334, "id": 62}, {"text": "the", "start": 335, "end": 338, "id": 63}, {"text": "graft", "start": 339, "end": 344, "id": 64}, {"text": "and", "start": 345, "end": 348, "id": 65}, {"text": "uncovering", "start": 349, "end": 359, "id": 66}, {"text": "of", "start": 360, "end": 362, "id": 67}, {"text": "the", "start": 363, "end": 366, "id": 68}, {"text": "screws", "start": 367, "end": 373, "id": 69}, {"text": ".", "start": 373, "end": 374, "id": 70}]}
{"pdf_hash": "6cc36b27b10280b5e90dba3a8e163f80c49e2698", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "Figure 6 Immunogold labelling of transgenic HSA-expressing chloroplasts. (a) Chloroplast (chl) labelled with anti-HSA antibody, where gold particles concentrate exclusively in the protein body (pb). (b) Anti-HSA immunogold labelling of a chloroplast expressing Trx\u2013HSA fusion. Gold particles decorate exclusively the protein bodies, independently of their size. (c\u2013e) Double immunolocalization of HSA (5 nm gold particles) and Trx (10 nm gold particles) in chloroplasts co-expressing both proteins. The signal corresponding to both proteins is found exclusively within the chloroplast, where it is distributed mostly with a dispersed pattern. However, some clusters are observed (arrowheads) where particles of anti-HSA and anti-Trx can be clearly seen to co-localize (d and e). ct: cytoplasm; mit: mitochondria. Bars in a\u2013b: 200 nm; c\u2013e: 100 nm. Trx, thioredoxin; HSA, human serum albumin.", "width": 624, "height": 692, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67], "c": [68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121], "d": [68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154], "e": [68, 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{"pdf_hash": "dfe01c65430dd8b43deeaae9dc3a599f7a2cdcce", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Figure 1 Extravillous trophoblast cells in the human uterine cavity. Immunocytochemical staining in utero with an antibody against HLA-G (and Hemalaun nuclear counterstain) in paraffin sections of an archived placenta (most likely early first trimester). The dark brown labeling of HLA-G serves as a marker for extravillous trophoblast (EVT) cells in the invasive zone between fetal and maternal regions. (a) An overview at the margin of the placenta showing villi and intervillous space, decidua basalis, decidua parietalis, decidua capsularis and the uterine cavity, as labeled. Details of the red insets in (a) follow: (b) demonstrates endoglandular EVTs (arrows) in the lumen of a gland near the edge of the placenta. (c) Shows an HLA-G positive EVT cell (arrow) located in the uterine cavity. (d) Shows an EVT cell (arrow) that has replaced the uterine epithelium, while others nearby approach the epithelium. 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{"pdf_hash": "f164ea464b2e644977cf8403e8536471ddf08694", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. T2 weighted MRIs show low signal changes like bone mass in sagittal view (A) and transverse view (B). These mass lesions show homogenous densities and slightly destructed cortex, red arrow: suspect ed mass lesions.", "width": 1010, "height": 474, "subcaptions": {"a": [15, 16, 17, 18, 19], "b": [21, 22, 23, 24, 25]}, "subfigures": [{"id": "03ba7540-79e3-44c6-b359-d57016c6915d", "label": "a", "points": [[4.1, 1.3], [4.1, 470.4], [476.3, 470.4], [476.3, 1.3]], "color": "yellow"}, {"id": "f0d84b77-32ef-4752-9374-86fdef679661", "label": "b", "points": [[490.7, 1.3], [490.7, 470.4], [975.8, 470.4], [975.8, 1.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "T2", "start": 8, "end": 10, "id": 4}, {"text": "weighted", "start": 11, "end": 19, "id": 5}, {"text": "MRIs", "start": 20, "end": 24, "id": 6}, {"text": "show", "start": 25, "end": 29, "id": 7}, {"text": "low", "start": 30, "end": 33, "id": 8}, {"text": "signal", "start": 34, "end": 40, "id": 9}, {"text": "changes", "start": 41, "end": 48, "id": 10}, {"text": "like", "start": 49, "end": 53, "id": 11}, {"text": "bone", "start": 54, "end": 58, "id": 12}, {"text": "mass", "start": 59, "end": 63, "id": 13}, {"text": "in", "start": 64, "end": 66, "id": 14}, {"text": "sagittal", "start": 67, "end": 75, "id": 15}, {"text": "view", "start": 76, "end": 80, "id": 16}, {"text": "(", "start": 81, "end": 82, "id": 17}, {"text": "A", "start": 82, "end": 83, "id": 18}, {"text": ")", "start": 83, "end": 84, "id": 19}, {"text": "and", "start": 85, "end": 88, "id": 20}, {"text": "transverse", "start": 89, "end": 99, "id": 21}, {"text": "view", "start": 100, "end": 104, "id": 22}, {"text": "(", "start": 105, "end": 106, "id": 23}, {"text": "B", "start": 106, "end": 107, "id": 24}, {"text": ")", "start": 107, "end": 108, "id": 25}, {"text": ".", "start": 108, "end": 109, "id": 26}, {"text": "These", "start": 110, "end": 115, "id": 27}, {"text": "mass", "start": 116, "end": 120, "id": 28}, {"text": "lesions", "start": 121, "end": 128, "id": 29}, {"text": "show", "start": 129, "end": 133, "id": 30}, {"text": "homogenous", "start": 134, "end": 144, "id": 31}, {"text": "densities", "start": 145, "end": 154, "id": 32}, {"text": "and", "start": 155, "end": 158, "id": 33}, {"text": "slightly", "start": 159, "end": 167, "id": 34}, {"text": "destructed", "start": 168, "end": 178, "id": 35}, {"text": "cortex", "start": 179, "end": 185, "id": 36}, {"text": ",", "start": 185, "end": 186, "id": 37}, {"text": "red", "start": 187, "end": 190, "id": 38}, {"text": "arrow", "start": 191, "end": 196, "id": 39}, {"text": ":", "start": 196, "end": 197, "id": 40}, {"text": "suspect", "start": 198, "end": 205, "id": 41}, {"text": "ed", "start": 206, "end": 208, "id": 42}, {"text": "mass", "start": 209, "end": 213, "id": 43}, {"text": "lesions", "start": 214, "end": 221, "id": 44}, {"text": ".", "start": 221, "end": 222, "id": 45}]}
{"pdf_hash": "f3cc749cda1c265853c7d77a464c2b715e493efc", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "FIG. 2. a-c. Transabdominal fetal ultrasound at 34th week. A central stripe in the well circumscribed left suprarenal mass demonstrates the normal adrenal gland (arrow) (a). On Doppler examination the mass has no vascularization (b). Transabdominal fetal ultrasound at 36th week of left adrenal mass. 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{"pdf_hash": "8dda9bc77b8d8457820962b96181813e1511e970", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Cardiac computed tomography angiography (CCTA) showing an intimal flap in the left main coronary artery (LM) and proximal left anterior descending coronary artery (LAD) (A). Image (B) shows the CCTA of right coronary artery (RCA) and its zoomed detail. Coronary angiography of the LAD in the right anterior oblique view (C). Note diffuse lumen narrowing involving the LM and the proximal and mid LAD (arrows). Coronary angiography of the RCA in the left anterior oblique view (D). Distal intraluminal linear filling defect is noted (arrows). Optical coherence tomography (OCT) from distal (E) to proximal (H ) in the LAD. Panel E indicates the intact three-layer aspect of the LAD just beyond the dissection. OCT depicting the presence of intramural haematoma in the LM (H, asterisk) and throughout the entire proximal and mid LAD (F and G, asterisk), showing an intimal flap (arrows) most likely as an entry point. OCT from distal (I ) to proximal (L) in the RCA. Images showing double lumen morphology (I and J ) with intimomedial dissection separating the true lumen (where probe is located) from the false lumen. Panel K shows the presence of intramural haematoma (asterisk). 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{"pdf_hash": "2944f7b05dd7b48c78b14c7a6c570851d9ce76e6", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. A 63-year-old female underwent left total knee arthroplasty. A. Note the degradation of the image quality of the 3.5 cm-long segment (between the two arrows) in the popliteal fossa on the threedimensional volume rendered image. B. An axial CT image shows the non-enhancing, low-attenuated lesions surrounded by contrast material within the left calf veins (asterisks). C. Color Doppler sonography reveals a hypoechoic lesion partially obstructing the left calf vein. 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{"pdf_hash": "d93017bf619bfa269a6bc1dce0ae13ce38d6762d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Standard venous phase (A) and excretory phase (B). Axial MDCT showed circular urothelial thickening of the upper ureter with no filling defects. Potential differential diagnosis were urothelial cancer, inflammatory disease and peristalsis in the ureter.", "width": 1094, "height": 652, "subcaptions": {"a": [3, 4, 5, 6, 7, 8], "b": [10, 11, 12, 13, 14]}, "subfigures": [{"id": "dce313ff-4356-4c48-af74-ad0e000378d3", "label": "a", "points": [[2.7, 3.2], [2.7, 621.9], [522.8, 621.9], [522.8, 3.2]], "color": "yellow"}, {"id": "730e559b-99fb-41c9-8590-639d441cdf97", "label": "b", "points": [[543.6, 1.4], [543.6, 621.9], [1062, 621.9], [1062, 1.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Standard", "start": 10, "end": 18, "id": 3}, {"text": "venous", "start": 19, "end": 25, "id": 4}, {"text": "phase", "start": 26, "end": 31, "id": 5}, {"text": "(", "start": 32, "end": 33, "id": 6}, {"text": "A", "start": 33, "end": 34, "id": 7}, {"text": ")", "start": 34, "end": 35, "id": 8}, {"text": "and", "start": 36, "end": 39, "id": 9}, {"text": "excretory", "start": 40, "end": 49, "id": 10}, {"text": "phase", "start": 50, "end": 55, "id": 11}, {"text": "(", "start": 56, "end": 57, "id": 12}, {"text": "B", "start": 57, "end": 58, "id": 13}, {"text": ")", "start": 58, "end": 59, "id": 14}, {"text": ".", "start": 59, "end": 60, "id": 15}, {"text": "Axial", "start": 61, "end": 66, "id": 16}, {"text": "MDCT", "start": 67, "end": 71, "id": 17}, {"text": "showed", "start": 72, "end": 78, "id": 18}, {"text": "circular", "start": 79, "end": 87, "id": 19}, {"text": "urothelial", "start": 88, "end": 98, "id": 20}, {"text": "thickening", "start": 99, "end": 109, "id": 21}, {"text": "of", "start": 110, "end": 112, "id": 22}, {"text": "the", "start": 113, "end": 116, "id": 23}, {"text": "upper", "start": 117, "end": 122, "id": 24}, {"text": "ureter", "start": 123, "end": 129, "id": 25}, {"text": "with", "start": 130, "end": 134, "id": 26}, {"text": "no", "start": 135, "end": 137, "id": 27}, {"text": "filling", "start": 138, "end": 145, "id": 28}, {"text": "defects", "start": 146, "end": 153, "id": 29}, {"text": ".", "start": 153, "end": 154, "id": 30}, {"text": "Potential", "start": 155, "end": 164, "id": 31}, {"text": "differential", "start": 165, "end": 177, "id": 32}, {"text": "diagnosis", "start": 178, "end": 187, "id": 33}, {"text": "were", "start": 188, "end": 192, "id": 34}, {"text": "urothelial", "start": 193, "end": 203, "id": 35}, {"text": "cancer", "start": 204, "end": 210, "id": 36}, {"text": ",", "start": 210, "end": 211, "id": 37}, {"text": "inflammatory", "start": 212, "end": 224, "id": 38}, {"text": "disease", "start": 225, "end": 232, "id": 39}, {"text": "and", "start": 233, "end": 236, "id": 40}, {"text": "peristalsis", "start": 237, "end": 248, "id": 41}, {"text": "in", "start": 249, "end": 251, "id": 42}, {"text": "the", "start": 252, "end": 255, "id": 43}, {"text": "ureter", "start": 256, "end": 262, "id": 44}, {"text": ".", "start": 262, "end": 263, "id": 45}]}
{"pdf_hash": "851c341d467913b3edd798dd88d0508225f584d8", "fig_key": "Figure8", "fig_uri": "5-Figure8-1.png", "text": "Figure 8. AP pelvis radiograph (a) and lateral view (b) 12 weeks after revision of the left acetabular shell and exchange to a polyethylene acetabular liner and a ceramic femoral head.", "width": 1116, "height": 546, "subcaptions": {"a": [3, 4, 5, 6, 7, 8], "b": [10, 11, 12, 13, 14]}, "subfigures": [{"id": "f6191264-7e8d-4e69-9405-fd1f97e3a764", "label": "a", "points": [[34, 6.8], [34, 511], [649.3, 511], [649.3, 6.8]], "color": "yellow"}, {"id": "3c1a4bfc-bf08-46d1-b0c4-03b80cb995c5", "label": "b", "points": [[658.1, 8.6], [658.1, 514.6], [1088.3, 514.6], [1088.3, 8.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "8", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "AP", "start": 10, "end": 12, "id": 3}, {"text": "pelvis", "start": 13, "end": 19, "id": 4}, {"text": "radiograph", "start": 20, "end": 30, "id": 5}, {"text": "(", "start": 31, "end": 32, "id": 6}, {"text": "a", "start": 32, "end": 33, "id": 7}, {"text": ")", "start": 33, "end": 34, "id": 8}, {"text": "and", "start": 35, "end": 38, "id": 9}, {"text": "lateral", "start": 39, "end": 46, "id": 10}, {"text": "view", "start": 47, "end": 51, "id": 11}, {"text": "(", "start": 52, "end": 53, "id": 12}, {"text": "b", "start": 53, "end": 54, "id": 13}, {"text": ")", "start": 54, "end": 55, "id": 14}, {"text": "12", "start": 56, "end": 58, "id": 15}, {"text": "weeks", "start": 59, "end": 64, "id": 16}, {"text": "after", "start": 65, "end": 70, "id": 17}, {"text": "revision", "start": 71, "end": 79, "id": 18}, {"text": "of", "start": 80, "end": 82, "id": 19}, {"text": "the", "start": 83, "end": 86, "id": 20}, {"text": "left", "start": 87, "end": 91, "id": 21}, {"text": "acetabular", "start": 92, "end": 102, "id": 22}, {"text": "shell", "start": 103, "end": 108, "id": 23}, {"text": "and", "start": 109, "end": 112, "id": 24}, {"text": "exchange", "start": 113, "end": 121, "id": 25}, {"text": "to", "start": 122, "end": 124, "id": 26}, {"text": "a", "start": 125, "end": 126, "id": 27}, {"text": "polyethylene", "start": 127, "end": 139, "id": 28}, {"text": "acetabular", "start": 140, "end": 150, "id": 29}, {"text": "liner", "start": 151, "end": 156, "id": 30}, {"text": "and", "start": 157, "end": 160, "id": 31}, {"text": "a", "start": 161, "end": 162, "id": 32}, {"text": "ceramic", "start": 163, "end": 170, "id": 33}, {"text": "femoral", "start": 171, "end": 178, "id": 34}, {"text": "head", "start": 179, "end": 183, "id": 35}, {"text": ".", "start": 183, "end": 184, "id": 36}]}
{"pdf_hash": "2cec8d6124f11a65000e9775d60ca7bc1ca87af5", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 Magnetic resonance imaging 1 week after the starting date of steroid treatment. a Sagittal: T2 signal hyperintensity lesion between T5 and T8 spinal levels was unclear. b Axial: T2 signal hyperintensity lesion in the center of the spinal cord at T7 spinal level shrunk", "width": 646, "height": 370, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50]}, "subfigures": [{"id": "05d8090d-0e98-4cbd-8c87-c097fcf25c07", "label": "a", "points": [[0, 0], [0, 369.4], [316.4, 369.4], [316.4, 0]], "color": "yellow"}, {"id": "ac109357-e157-4980-a720-135e3fac973c", "label": "b", "points": [[329.6, 299], [329.6, 2], [641.9, 2], [641.9, 299]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Magnetic", "start": 7, "end": 15, "id": 3}, {"text": "resonance", "start": 16, "end": 25, "id": 4}, {"text": "imaging", "start": 26, "end": 33, "id": 5}, {"text": "1", "start": 34, "end": 35, "id": 6}, {"text": "week", "start": 36, "end": 40, "id": 7}, {"text": "after", "start": 41, "end": 46, "id": 8}, {"text": "the", "start": 47, "end": 50, "id": 9}, {"text": "starting", "start": 51, "end": 59, "id": 10}, {"text": "date", "start": 60, "end": 64, "id": 11}, {"text": "of", "start": 65, "end": 67, "id": 12}, {"text": "steroid", "start": 68, "end": 75, "id": 13}, {"text": "treatment", "start": 76, "end": 85, "id": 14}, {"text": ".", "start": 85, "end": 86, "id": 15}, {"text": "a", "start": 87, "end": 88, "id": 16}, {"text": "Sagittal", "start": 89, "end": 97, "id": 17}, {"text": ":", "start": 97, "end": 98, "id": 18}, {"text": "T2", "start": 99, "end": 101, "id": 19}, {"text": "signal", "start": 102, "end": 108, "id": 20}, {"text": "hyperintensity", "start": 109, "end": 123, "id": 21}, {"text": "lesion", "start": 124, "end": 130, "id": 22}, {"text": "between", "start": 131, "end": 138, "id": 23}, {"text": "T5", "start": 139, "end": 141, "id": 24}, {"text": "and", "start": 142, "end": 145, "id": 25}, {"text": "T8", "start": 146, "end": 148, "id": 26}, {"text": "spinal", "start": 149, "end": 155, "id": 27}, {"text": "levels", "start": 156, "end": 162, "id": 28}, {"text": "was", "start": 163, "end": 166, "id": 29}, {"text": "unclear", "start": 167, "end": 174, "id": 30}, {"text": ".", "start": 174, "end": 175, "id": 31}, {"text": "b", "start": 176, "end": 177, "id": 32}, {"text": "Axial", "start": 178, "end": 183, "id": 33}, {"text": ":", "start": 183, "end": 184, "id": 34}, {"text": "T2", "start": 185, "end": 187, "id": 35}, {"text": "signal", "start": 188, "end": 194, "id": 36}, {"text": "hyperintensity", "start": 195, "end": 209, "id": 37}, {"text": "lesion", "start": 210, "end": 216, "id": 38}, {"text": "in", "start": 217, "end": 219, "id": 39}, {"text": "the", "start": 220, "end": 223, "id": 40}, {"text": "center", "start": 224, "end": 230, "id": 41}, {"text": "of", "start": 231, "end": 233, "id": 42}, {"text": "the", "start": 234, "end": 237, "id": 43}, {"text": "spinal", "start": 238, "end": 244, "id": 44}, {"text": "cord", "start": 245, "end": 249, "id": 45}, {"text": "at", "start": 250, "end": 252, "id": 46}, {"text": "T7", "start": 253, "end": 255, "id": 47}, {"text": "spinal", "start": 256, "end": 262, "id": 48}, {"text": "level", "start": 263, "end": 268, "id": 49}, {"text": "shrunk", "start": 269, "end": 275, "id": 50}]}
{"pdf_hash": "0589b65f08a9f2cfee3d3f54312e4644a1d3dd12", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Figure 6. A representative image set for quantitative analysis of dual-energy CT of a cardiac tumor. Three modes of images were obtained using dual-energy CT: (A) a monochromatic 70 keV image representing the post-contrast CT image, (B) a MSI image representing the pre-contrast CT image, and (C) an iodine (water) image; A volume of interest covering the entire cardiac mass was drawn on the image of each mode on the identical level of the cardiac tumor.", "width": 900, "height": 296, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61], "c": [63, 64, 65, 66, 67, 68, 69, 70, 71]}, "subfigures": [{"id": "0bf0fd88-305d-4c51-b815-0fd70fce6186", "label": "a", "points": [[5, 2.6], [5, 289.8], [290.8, 289.8], [290.8, 2.6]], "color": "yellow"}, {"id": "3e5d57ca-7226-4bbf-a50d-e8dcfe636bb6", "label": "b", "points": [[300.8, 5.5], [300.8, 287], [590.8, 287], [590.8, 5.5]], "color": "cyan"}, {"id": "a48cc687-bcbe-4629-ad7f-4276c2f4eee4", "label": "c", "points": [[599.3, 4], [599.3, 288.4], [895, 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{"pdf_hash": "d9b0255dd405ec7dd088cd753eaaea9e8b2a9238", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Scanning electron microscopy (SEM) image of the cross-section of PZT-PWAS: (a) at room temperature; (b) after exposure to 250 \u2022 C temperature; (c) after exposure to 225 kGy nuclear radiation.", "width": 1188, "height": 724, "subcaptions": {"a": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "e613d7cd-75cb-4cba-bab8-b3a6b474e9f1", "label": "a", "points": [[8.5, 11], [8.5, 318.7], [380.1, 318.7], [380.1, 11]], "color": "yellow"}, {"id": "02e3499a-7ddf-4d90-a573-299216a8955c", "label": "a", "points": [[14.1, 330], [14.1, 632.1], [378.2, 632.1], [378.2, 330]], "color": "cyan"}, {"id": "c6e47c66-7393-4e19-b61b-2172ba75d66c", "label": "b", "points": [[402.6, 11], [402.6, 318.7], [768.6, 318.7], [768.6, 11]], "color": "magenta"}, {"id": "75d921e3-8380-4e3a-bd74-1bc61e61efcd", "label": "b", "points": [[406.4, 331.9], [406.4, 632.1], [766.7, 632.1], [766.7, 331.9]], "color": "springgreen"}, {"id": "77785df9-fe48-40a2-b30a-19baba544c9c", "label": "c", "points": [[791.1, 9.1], [791.1, 315], [1175.8, 315], [1175.8, 9.1]], "color": "tomato"}, {"id": "854238db-9adc-4913-a546-0d626595022e", "label": "c", "points": [[785.5, 330], [785.5, 639.7], [1177.7, 639.7], [1177.7, 330]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Scanning", "start": 10, "end": 18, "id": 3}, {"text": "electron", "start": 19, "end": 27, "id": 4}, {"text": "microscopy", "start": 28, "end": 38, "id": 5}, {"text": "(", "start": 39, "end": 40, "id": 6}, {"text": "SEM", "start": 40, "end": 43, "id": 7}, {"text": ")", "start": 43, "end": 44, "id": 8}, {"text": "image", "start": 45, "end": 50, "id": 9}, {"text": "of", "start": 51, "end": 53, "id": 10}, {"text": "the", "start": 54, "end": 57, "id": 11}, {"text": "cross", "start": 58, "end": 63, "id": 12}, {"text": "-", "start": 63, "end": 64, "id": 13}, {"text": "section", "start": 64, "end": 71, "id": 14}, {"text": "of", "start": 72, "end": 74, "id": 15}, {"text": "PZT", "start": 75, "end": 78, "id": 16}, {"text": "-", "start": 78, "end": 79, "id": 17}, {"text": "PWAS", "start": 79, "end": 83, "id": 18}, {"text": ":", "start": 83, "end": 84, "id": 19}, {"text": "(", "start": 85, "end": 86, "id": 20}, {"text": "a", "start": 86, "end": 87, "id": 21}, {"text": ")", "start": 87, "end": 88, "id": 22}, {"text": "at", "start": 89, "end": 91, "id": 23}, {"text": "room", "start": 92, "end": 96, "id": 24}, {"text": "temperature", "start": 97, "end": 108, "id": 25}, {"text": ";", "start": 108, "end": 109, "id": 26}, {"text": "(", "start": 110, "end": 111, "id": 27}, {"text": "b", "start": 111, "end": 112, "id": 28}, {"text": ")", "start": 112, "end": 113, "id": 29}, {"text": "after", "start": 114, "end": 119, "id": 30}, {"text": "exposure", "start": 120, "end": 128, "id": 31}, {"text": "to", "start": 129, "end": 131, "id": 32}, {"text": "250", "start": 132, "end": 135, "id": 33}, {"text": "\u2022", "start": 136, "end": 137, "id": 34}, {"text": "C", "start": 138, "end": 139, "id": 35}, {"text": "temperature", "start": 140, "end": 151, "id": 36}, {"text": ";", "start": 151, "end": 152, "id": 37}, {"text": "(", "start": 153, "end": 154, "id": 38}, {"text": "c", "start": 154, "end": 155, "id": 39}, {"text": ")", "start": 155, "end": 156, "id": 40}, {"text": "after", "start": 157, "end": 162, "id": 41}, {"text": "exposure", "start": 163, "end": 171, "id": 42}, {"text": "to", "start": 172, "end": 174, "id": 43}, {"text": "225", "start": 175, "end": 178, "id": 44}, {"text": "kGy", "start": 179, "end": 182, "id": 45}, {"text": "nuclear", "start": 183, "end": 190, "id": 46}, {"text": "radiation", "start": 191, "end": 200, "id": 47}, {"text": ".", "start": 200, "end": 201, "id": 48}]}
{"pdf_hash": "d81bc0eddf582ed8d57c1cabe334854bb4976374", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIG. 1. Example healthy volunteer MRSI grid placement for: above the corpus callosum sagittal (A) and axial (B) views and the basal ganglia sagittal (C) and axial (D) views. Water line width map is included for corpus callosum (B) and basal ganglia (D) for the PRESS excitation region.", "width": 1002, "height": 944, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19], "b": [12, 13, 14, 15, 21, 22, 23, 24, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 59, 60, 61, 62, 63, 64], "c": [32, 33, 27, 28, 29, 30, 31], "d": [27, 28, 29, 35, 36, 37, 38, 41, 42, 43, 44, 45, 46, 47, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "46cacc5d-f02b-42f7-8b7f-9e4182c8c25f", "label": "a", "points": [[1.6, 3.2], [1.6, 471.7], [455.9, 471.7], [455.9, 3.2]], "color": "yellow"}, {"id": "419dbc53-1394-4b5c-a703-87038ea5c530", "label": "b", "points": [[460.6, 1.6], [460.6, 471.7], [840.6, 471.7], [840.6, 1.6]], "color": "cyan"}, {"id": "705d18a5-2a21-46b5-88ea-4a55cbf153e4", "label": "c", "points": [[6.3, 486], [6.3, 934], [449.6, 934], [449.6, 486]], "color": "magenta"}, {"id": "17c8b320-56ea-4774-aa3b-2f4bea3ade1e", "label": "d", "points": [[463.8, 478.1], [463.8, 934], [843.7, 934], [843.7, 478.1]], "color": "springgreen"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Example", "start": 8, "end": 15, "id": 4}, {"text": "healthy", "start": 16, "end": 23, "id": 5}, {"text": "volunteer", "start": 24, "end": 33, "id": 6}, {"text": "MRSI", "start": 34, "end": 38, "id": 7}, {"text": "grid", "start": 39, "end": 43, "id": 8}, {"text": "placement", "start": 44, "end": 53, "id": 9}, {"text": "for", "start": 54, "end": 57, "id": 10}, {"text": ":", "start": 57, "end": 58, "id": 11}, {"text": "above", "start": 59, "end": 64, "id": 12}, {"text": "the", "start": 65, "end": 68, "id": 13}, {"text": "corpus", "start": 69, "end": 75, "id": 14}, {"text": "callosum", "start": 76, "end": 84, "id": 15}, {"text": "sagittal", "start": 85, "end": 93, "id": 16}, {"text": "(", "start": 94, "end": 95, "id": 17}, {"text": "A", "start": 95, "end": 96, "id": 18}, {"text": ")", "start": 96, "end": 97, "id": 19}, {"text": "and", "start": 98, "end": 101, "id": 20}, {"text": "axial", "start": 102, "end": 107, "id": 21}, {"text": "(", "start": 108, "end": 109, "id": 22}, {"text": "B", "start": 109, "end": 110, "id": 23}, {"text": ")", "start": 110, "end": 111, "id": 24}, {"text": "views", "start": 112, "end": 117, "id": 25}, {"text": "and", "start": 118, "end": 121, "id": 26}, {"text": "the", "start": 122, "end": 125, "id": 27}, {"text": "basal", "start": 126, "end": 131, "id": 28}, {"text": "ganglia", "start": 132, "end": 139, "id": 29}, {"text": "sagittal", "start": 140, "end": 148, "id": 30}, {"text": "(", "start": 149, "end": 150, "id": 31}, {"text": "C", "start": 150, "end": 151, "id": 32}, {"text": ")", "start": 151, "end": 152, "id": 33}, {"text": "and", "start": 153, "end": 156, "id": 34}, {"text": "axial", "start": 157, "end": 162, "id": 35}, {"text": "(", "start": 163, "end": 164, "id": 36}, {"text": "D", "start": 164, "end": 165, "id": 37}, {"text": ")", "start": 165, "end": 166, "id": 38}, {"text": "views", "start": 167, "end": 172, "id": 39}, {"text": ".", "start": 172, "end": 173, "id": 40}, {"text": "Water", "start": 174, "end": 179, "id": 41}, {"text": "line", "start": 180, "end": 184, "id": 42}, {"text": "width", "start": 185, "end": 190, "id": 43}, {"text": "map", "start": 191, "end": 194, "id": 44}, {"text": "is", "start": 195, "end": 197, "id": 45}, {"text": "included", "start": 198, "end": 206, "id": 46}, {"text": "for", "start": 207, "end": 210, "id": 47}, {"text": "corpus", "start": 211, "end": 217, "id": 48}, {"text": "callosum", "start": 218, "end": 226, "id": 49}, {"text": "(", "start": 227, "end": 228, "id": 50}, {"text": "B", "start": 228, "end": 229, "id": 51}, {"text": ")", "start": 229, "end": 230, "id": 52}, {"text": "and", "start": 231, "end": 234, "id": 53}, {"text": "basal", "start": 235, "end": 240, "id": 54}, {"text": "ganglia", "start": 241, "end": 248, "id": 55}, {"text": "(", "start": 249, "end": 250, "id": 56}, {"text": "D", "start": 250, "end": 251, "id": 57}, {"text": ")", "start": 251, "end": 252, "id": 58}, {"text": "for", "start": 253, "end": 256, "id": 59}, {"text": "the", "start": 257, "end": 260, "id": 60}, {"text": "PRESS", "start": 261, "end": 266, "id": 61}, {"text": "excitation", "start": 267, "end": 277, "id": 62}, {"text": "region", "start": 278, "end": 284, "id": 63}, {"text": ".", "start": 284, "end": 285, "id": 64}]}
{"pdf_hash": "42dbc5c07941eac7b637117ea262f8a9990b6b87", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2 Iris and ciliary body tumour in the right eye of a 72-year-old woman (a) treated with cyclo-iridectomy. On high-frequency ultrasonography the tumour measured 3.0 by 3.5 mm basally, with a thickness of 1.5 mm (b). One clock hour of ciliary body was involved. Six weeks after surgery, the visual acuity was 6/9 (c). Ultrasound scan showing the resection site (d). 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{"pdf_hash": "8bb081311e53df02b3e3d8f36f8334e052f68f94", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Pre-and postoperative imaging: (A) clinical target volume (red) of the left supraclavicular region; (B) clinical target volume (red) of the mediastinum; (C) clinical target volume (red) of the abdominal cavity (A-C) gross tumor volume and planning target volume contours omitted for clarity); (D) gastric endoscopy showing anastomotic stenosis due to gastric cancer with intragastric hemorrhage; (E) PET-CT showing extensive distant metastasis in supraclavicular lymph nodes (arrow), the mediastinum (arrow), and multiple parts of the abdominal cavity (circle and arrow) before concurrent apatinib and radiotherapy; (F) PET-CT showing a partial response in the supraclavicular lymph nodes, mediastinum, and multiple parts of the abdominal cavity after concurrent apatinib and radiotherapy. 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{"pdf_hash": "982ed91b1d54d69dc9863043379718d54fa6c2f6", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIG. 1. (a) Ouchterlony double-diffusion analysis of 0.6M NaCl extract from Novikoff hepatoma nuclear chromatin. An aliquot of 0.6 M NaCl extract (50 Al) was placed in well A and antiserum in well B. Protein concentrations for all extracts and antisera were 15 mg/ml. Plates were incubated at 250 in a moist chamber. The precipitin lines formed after 18 hr of diffusion. (b) Ouchterlony double-diffusion analysis of 0.6 M NaCl extracts from Novikoff hepatoma and Walker 256 carcinosarcoma chromatins. A 50-gl aliquot of the extract of Novikoff hepatoma (15 mg/ml) was placed in well A and a 50-,l aliquot of the extract of Walker 256 carcinosarcoma (15 mg/ml) in well B. Antiserum (15 mg/ml) was placed in well C. The precipitin bands shown were detected within 18 hr of diffusion. (c) Ouchterlony double-diffusion analysis of preadsorbed antiserum. Antiserum was adsorbed exhaustively with 0.6M NaCl extract (15 mg/ml) from 18-hr regenerating rat liver chromatin before placement in well A. Fifty microliters of 0.6 M NaCl extract of Novikoff hepatoma chromatin (15 mg/ml) was placed in well B. 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{"pdf_hash": "d6c7dfc4426576a0f8674c352454b600cb6992be", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1 (A) Sagital T1FSE; (B, C) Coronal and axial T2FSE; (D) Axial FLAIR; (E, F): anisotropic diffusion study (b1000 and ADC map, respectively). The images show a symmetric central pontine lesion (arrows), sparing the peripheral fi bres, with a typical trident shape and areas of restricted diffusion. 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{"pdf_hash": "c4dde4d7eefbbd2b25cb8c690b2f7be38804f7ec", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. T1-weighted (A) and short-tau inversion recovery (B) sagittal images showing liquid retention at the facet joint of L4/L5 (white arrowhead).", "width": 980, "height": 462, "subcaptions": {"a": [3, 4, 5, 6], "b": [8, 9, 10, 11, 12, 13, 14, 15]}, "subfigures": [{"id": "3304aacb-7829-4995-8a3c-a90ff8988074", "label": "a", "points": [[6.5, 2.1], [6.5, 434], [466.3, 434], [466.3, 2.1]], "color": "yellow"}, {"id": "a050bdcd-5c81-42c3-b9b4-6c6f4faf8d87", "label": "b", "points": [[489.5, 2.1], [489.5, 437.1], [943.2, 437.1], [943.2, 2.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "T1-weighted", "start": 10, "end": 21, "id": 3}, {"text": "(", "start": 22, "end": 23, "id": 4}, {"text": "A", "start": 23, "end": 24, "id": 5}, {"text": ")", "start": 24, "end": 25, "id": 6}, {"text": "and", "start": 26, "end": 29, "id": 7}, {"text": "short", "start": 30, "end": 35, "id": 8}, {"text": "-", "start": 35, "end": 36, "id": 9}, {"text": "tau", "start": 36, "end": 39, "id": 10}, {"text": "inversion", "start": 40, "end": 49, "id": 11}, {"text": "recovery", "start": 50, "end": 58, "id": 12}, {"text": "(", "start": 59, "end": 60, "id": 13}, {"text": "B", "start": 60, "end": 61, "id": 14}, {"text": ")", "start": 61, "end": 62, "id": 15}, {"text": "sagittal", "start": 63, "end": 71, "id": 16}, {"text": "images", "start": 72, "end": 78, "id": 17}, {"text": "showing", "start": 79, "end": 86, "id": 18}, {"text": "liquid", "start": 87, "end": 93, "id": 19}, {"text": "retention", "start": 94, "end": 103, "id": 20}, {"text": "at", "start": 104, "end": 106, "id": 21}, {"text": "the", "start": 107, "end": 110, "id": 22}, {"text": "facet", "start": 111, "end": 116, "id": 23}, {"text": "joint", "start": 117, "end": 122, "id": 24}, {"text": "of", "start": 123, "end": 125, "id": 25}, {"text": "L4", "start": 126, "end": 128, "id": 26}, {"text": "/", "start": 128, "end": 129, "id": 27}, {"text": "L5", "start": 129, "end": 131, "id": 28}, {"text": "(", "start": 132, "end": 133, "id": 29}, {"text": "white", "start": 133, "end": 138, "id": 30}, {"text": "arrowhead", "start": 139, "end": 148, "id": 31}, {"text": ")", "start": 148, "end": 149, "id": 32}, {"text": ".", "start": 149, "end": 150, "id": 33}]}
{"pdf_hash": "3e68888bb650c744f617d67eacfdf7301b4a24cf", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3 MRI features in tremor\u2212ataxia with central hypomyelination (TACH). Characteristic MRI images in two subjects: cases 5 (a) and 7 (b) (the least and most affected patients, at ages 11 and 21 years, respectively). The MRI show diffuse hypomyelination with diffusely increased T2 signal, isointense or hyperintense T1 signal, with relative sparing of arcuate fibers and optic radiations. Thinning of the corpus callosum is a constant feature. In the most clinically affected patients, such as in case 7, there is some periventricular deep white matter rarefaction on FLAIR images, as well as atrophy of the cerebellum", "width": 1044, "height": 822, "subcaptions": {"a": [33, 36, 37, 41, 44, 22, 23, 24, 25], "b": [27, 28, 29, 30, 35, 36, 37, 43, 44, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117]}, "subfigures": [{"id": "2e74fbf9-9bf2-49ea-be80-e18c532f6c8f", "label": "a", "points": [[33.3, 105.6], [33.3, 394.2], [1041, 394.2], [1041, 105.6]], "color": "yellow"}, {"id": "05a59b4e-c156-461a-ab28-157c03fd33af", "label": "b", "points": [[31.6, 423.9], [31.6, 813.1], [1037.7, 813.1], [1037.7, 423.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "MRI", "start": 7, "end": 10, "id": 3}, {"text": "features", 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{"pdf_hash": "2a3448ced38f7cc29f5d6accaa3e6ad718210a99", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3 (a&b) MR coronal and (c) axial images showed well defined mass above the medial epicondyle with ulnar nerve compression (arrowed).", "width": 1014, "height": 548, "subcaptions": {"a": [2, 3, 4, 5, 6], "b": [2, 3, 4, 5, 6], "c": [8, 9, 10, 11]}, "subfigures": [{"id": "5f188f73-e886-4ced-b49c-7401ae20bb7f", "label": "a", "points": [[40.3, 19.8], [40.3, 526], [540.1, 526], [540.1, 19.8]], "color": "yellow"}, {"id": "155def1e-c682-465e-95cf-c98de6005a77", "label": "b", "points": [[543.3, 21.4], [543.3, 295.3], [975.9, 295.3], [975.9, 21.4]], "color": "cyan"}, {"id": "15fb1832-a7f7-4f7b-930d-996c43b485e4", "label": "c", "points": [[551.3, 302.8], [551.3, 530.2], [769.2, 530.2], [769.2, 302.8]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a&b", "start": 10, "end": 13, "id": 3}, {"text": ")", "start": 13, "end": 14, "id": 4}, {"text": "MR", "start": 15, "end": 17, "id": 5}, {"text": "coronal", "start": 18, "end": 25, "id": 6}, {"text": "and", "start": 26, "end": 29, "id": 7}, {"text": "(", "start": 30, "end": 31, "id": 8}, {"text": "c", "start": 31, "end": 32, "id": 9}, {"text": ")", "start": 32, "end": 33, "id": 10}, {"text": "axial", "start": 34, "end": 39, "id": 11}, {"text": "images", "start": 40, "end": 46, "id": 12}, {"text": "showed", "start": 47, "end": 53, "id": 13}, {"text": "well", "start": 54, "end": 58, "id": 14}, {"text": "defined", "start": 59, "end": 66, "id": 15}, {"text": "mass", "start": 67, "end": 71, "id": 16}, {"text": "above", "start": 72, "end": 77, "id": 17}, {"text": "the", "start": 78, "end": 81, "id": 18}, {"text": "medial", "start": 82, "end": 88, "id": 19}, {"text": "epicondyle", "start": 89, "end": 99, "id": 20}, {"text": "with", "start": 100, "end": 104, "id": 21}, {"text": "ulnar", "start": 105, "end": 110, "id": 22}, {"text": "nerve", "start": 111, "end": 116, "id": 23}, {"text": "compression", "start": 117, "end": 128, "id": 24}, {"text": "(", "start": 129, "end": 130, "id": 25}, {"text": "arrowed", "start": 130, "end": 137, "id": 26}, {"text": ")", "start": 137, "end": 138, "id": 27}, {"text": ".", "start": 138, "end": 139, "id": 28}]}
{"pdf_hash": "48d31df337a3b9009755337592259ae9f463498e", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Immunohistochemical staining for hMLH1 protein expression in gastric cancers with unmethylated (A) or hypermethylated (B) gene promoters. (A) Nuclear staining of hMLH1 in a MSS tumour without promoter hypermethylation (intramucosal well differentiated tubular adenocarcinoma). (B) Loss of hMLH1 expression in a MSI-H tumour with promoter hypermethylation (left, intramucosal well differentiated tubular adenocarcinoma; right, intestinal metaplastic mucosa exhibiting hMLH1 expression).", "width": 640, "height": 822, "subcaptions": {"a": [12, 13, 14, 15, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "b": [17, 18, 19, 20, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80]}, "subfigures": [{"id": "719ee37e-73ac-477b-90c4-4fd53326a5e0", "label": "a", "points": [[38, 30.2], [38, 405.2], [602.1, 405.2], [602.1, 30.2]], "color": "yellow"}, {"id": "c206b695-408f-436b-84b3-8f95539794cb", "label": "b", "points": [[39, 418.4], [39, 790.4], [604.1, 790.4], [604.1, 418.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Immunohistochemical", "start": 9, 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{"pdf_hash": "2ee9d36c75c70aa3c43b0814525c2dc62f8c5f78", "fig_key": "Figure5", "fig_uri": "12-Figure5-1.png", "text": "Fig. 5. MRI brain studies of patient with MMA. (a) Axial flair demonstrating infraction of the lenticular nuclei bilaterally. (b) Axial T2 image demonstrating a right cerebellar infarct.", "width": 1110, "height": 1400, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36]}, "subfigures": [{"id": "b6299207-58b5-4a93-abb8-10ae6b734790", "label": "a", "points": [[5.6, 1.2], [5.6, 690.3], [1103.3, 690.3], [1103.3, 1.2]], "color": "yellow"}, {"id": "29f8411b-009e-47a8-a53c-24fe9cc8e56c", "label": "b", "points": [[3.8, 711.4], [3.8, 1391.7], [1105, 1391.7], [1105, 711.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "MRI", "start": 8, "end": 11, "id": 4}, {"text": "brain", "start": 12, "end": 17, "id": 5}, {"text": "studies", "start": 18, "end": 25, "id": 6}, {"text": "of", "start": 26, "end": 28, "id": 7}, {"text": "patient", "start": 29, "end": 36, "id": 8}, {"text": "with", "start": 37, "end": 41, "id": 9}, {"text": "MMA", "start": 42, "end": 45, "id": 10}, {"text": ".", "start": 45, "end": 46, "id": 11}, {"text": "(", "start": 47, "end": 48, "id": 12}, {"text": "a", "start": 48, "end": 49, "id": 13}, {"text": ")", "start": 49, "end": 50, "id": 14}, {"text": "Axial", "start": 51, "end": 56, "id": 15}, {"text": "flair", "start": 57, "end": 62, "id": 16}, {"text": "demonstrating", "start": 63, "end": 76, "id": 17}, {"text": "infraction", "start": 77, "end": 87, "id": 18}, {"text": "of", "start": 88, "end": 90, "id": 19}, {"text": "the", "start": 91, "end": 94, "id": 20}, {"text": "lenticular", "start": 95, "end": 105, "id": 21}, {"text": "nuclei", "start": 106, "end": 112, "id": 22}, {"text": "bilaterally", "start": 113, "end": 124, "id": 23}, {"text": ".", "start": 124, "end": 125, "id": 24}, {"text": "(", "start": 126, "end": 127, "id": 25}, {"text": "b", "start": 127, "end": 128, "id": 26}, {"text": ")", "start": 128, "end": 129, "id": 27}, {"text": "Axial", "start": 130, "end": 135, "id": 28}, {"text": "T2", "start": 136, "end": 138, "id": 29}, {"text": "image", "start": 139, "end": 144, "id": 30}, {"text": "demonstrating", "start": 145, "end": 158, "id": 31}, {"text": "a", "start": 159, "end": 160, "id": 32}, {"text": "right", "start": 161, "end": 166, "id": 33}, {"text": "cerebellar", "start": 167, "end": 177, "id": 34}, {"text": "infarct", "start": 178, "end": 185, "id": 35}, {"text": ".", "start": 185, "end": 186, "id": 36}]}
{"pdf_hash": "291855539c0320df459f56a911ffa1a175cb6818", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4. Changes in laser speckle flowgraphy and enhanced depth imaging optical coherence tomography findings in the amblyopic eye in case 2. A laser speckle flowgraphy color map and enhanced depth imaging optical coherence tomography images of the right eye at 2 months (A and B) and 8 months (C and D) after the first visit are shown. The mean blur rates were 11.4 and 13.4 at 2 and 8 months after the first visit, respectively. The central choroidal thickness of the right eye was 294 mm and 287 mm at 2 and 8 months after the first visit, respectively. 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{"pdf_hash": "e067a2a545e52efe5ee69d67d0fe9899927ceee4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 \u2013 A) View of the aortic paravalvular regurgitant jet in a transesophageal echocardiogram. B and C) Picture showing the multipurpose catheter in an angiography to identify the leak. D) Amplatzer positioned to check location prior to occlusive device implantation. AV=aortic valve; OA=occlusive Amplatzer; PVL=paravalvular leak", "width": 1398, "height": 1070, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [32, 33, 34, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [32, 33, 34, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "d": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "1d83fb5e-e445-4660-90a1-edbba6d682bb", "label": "a", "points": [[4.4, 6.6], [4.4, 521.2], [580.8, 521.2], [580.8, 6.6]], "color": "yellow"}, {"id": "a891e2db-17ca-4432-90b7-8d8168932e11", "label": "b", "points": [[587.5, 521.2], [587.5, 2.2], [1393.6, 2.2], [1393.6, 521.2]], "color": "cyan"}, {"id": "41d05514-be36-45eb-8de5-48f936b77e4b", "label": "c", "points": [[678, 1044.6], [678, 527.8], [4.4, 527.8], [4.4, 1044.6]], "color": "magenta"}, {"id": "11020a90-9725-4d6a-b5ce-88d1aad31298", "label": "d", "points": [[684.6, 1042.4], [684.6, 523.4], [1391.4, 523.4], [1391.4, 1042.4]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "A", "start": 9, "end": 10, "id": 4}, {"text": ")", "start": 10, "end": 11, "id": 5}, {"text": "View", "start": 12, "end": 16, "id": 6}, {"text": "of", "start": 17, "end": 19, "id": 7}, {"text": "the", "start": 20, "end": 23, "id": 8}, {"text": "aortic", "start": 24, "end": 30, "id": 9}, {"text": "paravalvular", "start": 31, "end": 43, "id": 10}, {"text": "regurgitant", "start": 44, "end": 55, "id": 11}, {"text": "jet", "start": 56, "end": 59, "id": 12}, {"text": "in", "start": 60, "end": 62, "id": 13}, {"text": "a", "start": 63, "end": 64, "id": 14}, {"text": "transesophageal", "start": 65, "end": 80, "id": 15}, {"text": "echocardiogram", "start": 81, "end": 95, "id": 16}, {"text": ".", "start": 95, "end": 96, "id": 17}, {"text": "B", "start": 97, "end": 98, "id": 18}, {"text": "and", "start": 99, "end": 102, "id": 19}, {"text": "C", "start": 103, "end": 104, "id": 20}, {"text": ")", "start": 104, "end": 105, "id": 21}, {"text": "Picture", "start": 106, "end": 113, "id": 22}, {"text": "showing", "start": 114, "end": 121, "id": 23}, {"text": "the", "start": 122, "end": 125, "id": 24}, {"text": "multipurpose", "start": 126, "end": 138, "id": 25}, {"text": "catheter", "start": 139, "end": 147, "id": 26}, {"text": "in", "start": 148, "end": 150, "id": 27}, {"text": "an", "start": 151, "end": 153, "id": 28}, {"text": "angiography", "start": 154, "end": 165, "id": 29}, {"text": "to", "start": 166, "end": 168, "id": 30}, {"text": "identify", "start": 169, "end": 177, "id": 31}, {"text": "the", "start": 178, "end": 181, "id": 32}, {"text": "leak", "start": 182, "end": 186, "id": 33}, {"text": ".", "start": 186, "end": 187, "id": 34}, {"text": "D", "start": 188, "end": 189, "id": 35}, {"text": ")", "start": 189, "end": 190, "id": 36}, {"text": "Amplatzer", "start": 191, "end": 200, "id": 37}, {"text": "positioned", "start": 201, "end": 211, "id": 38}, {"text": "to", "start": 212, "end": 214, "id": 39}, {"text": "check", "start": 215, "end": 220, "id": 40}, {"text": "location", "start": 221, "end": 229, "id": 41}, {"text": "prior", "start": 230, "end": 235, "id": 42}, {"text": "to", "start": 236, "end": 238, "id": 43}, {"text": "occlusive", "start": 239, "end": 248, "id": 44}, {"text": "device", "start": 249, "end": 255, "id": 45}, {"text": "implantation", "start": 256, "end": 268, "id": 46}, {"text": ".", "start": 268, "end": 269, "id": 47}, {"text": "AV", "start": 270, "end": 272, "id": 48}, {"text": "=", "start": 272, "end": 273, "id": 49}, {"text": "aortic", "start": 273, "end": 279, "id": 50}, {"text": "valve", "start": 280, "end": 285, "id": 51}, {"text": ";", "start": 285, "end": 286, "id": 52}, {"text": "OA", "start": 287, "end": 289, "id": 53}, {"text": "=", "start": 289, "end": 290, "id": 54}, {"text": "occlusive", "start": 290, "end": 299, "id": 55}, {"text": "Amplatzer", "start": 300, "end": 309, "id": 56}, {"text": ";", "start": 309, "end": 310, "id": 57}, {"text": "PVL", "start": 311, "end": 314, "id": 58}, {"text": "=", "start": 314, "end": 315, "id": 59}, {"text": "paravalvular", "start": 315, "end": 327, "id": 60}, {"text": "leak", "start": 328, "end": 332, "id": 61}]}
{"pdf_hash": "54cdb20e6bdb2aea2966049f2de3de07a4a434c2", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "FIGURE 3. Blood-oxygen level-dependent magnetic resonance imaging Blood-oxygen level-dependent magnetic resonance imaging from normal (left) and stenotic (right) swine kidneys. Cortical and medullary hypoxic (red) regions are observed in the poststenotic kidney.", "width": 884, "height": 480, "subcaptions": {"a": [22, 23, 24, 25], "b": [27, 28, 29, 30]}, "subfigures": [{"id": "1a6e7849-1399-4a40-af2c-33826df6d38a", "label": "a", "points": [[14.7, 45.9], [14.7, 438.2], [408.5, 438.2], [408.5, 45.9]], "color": "yellow"}, {"id": "03a7295d-553d-4d3b-8836-265e1cda64fd", "label": "b", "points": [[415.5, 43.1], [415.5, 439.6], [775.8, 439.6], [775.8, 43.1]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Blood", "start": 10, "end": 15, "id": 3}, {"text": "-", "start": 15, "end": 16, "id": 4}, {"text": "oxygen", "start": 16, "end": 22, "id": 5}, {"text": "level", "start": 23, "end": 28, "id": 6}, {"text": "-", "start": 28, "end": 29, "id": 7}, {"text": "dependent", "start": 29, "end": 38, "id": 8}, {"text": "magnetic", "start": 39, "end": 47, "id": 9}, {"text": "resonance", "start": 48, "end": 57, "id": 10}, {"text": "imaging", "start": 58, "end": 65, "id": 11}, {"text": "Blood", "start": 66, "end": 71, "id": 12}, {"text": "-", "start": 71, "end": 72, "id": 13}, {"text": "oxygen", "start": 72, "end": 78, "id": 14}, {"text": "level", "start": 79, "end": 84, "id": 15}, {"text": "-", "start": 84, "end": 85, "id": 16}, {"text": "dependent", "start": 85, "end": 94, "id": 17}, {"text": "magnetic", "start": 95, "end": 103, "id": 18}, {"text": "resonance", "start": 104, "end": 113, "id": 19}, {"text": "imaging", "start": 114, "end": 121, "id": 20}, {"text": "from", "start": 122, "end": 126, "id": 21}, {"text": "normal", "start": 127, "end": 133, "id": 22}, {"text": "(", "start": 134, "end": 135, "id": 23}, {"text": "left", "start": 135, "end": 139, "id": 24}, {"text": ")", "start": 139, "end": 140, "id": 25}, {"text": "and", "start": 141, "end": 144, "id": 26}, {"text": "stenotic", "start": 145, "end": 153, "id": 27}, {"text": "(", "start": 154, "end": 155, "id": 28}, {"text": "right", "start": 155, "end": 160, "id": 29}, {"text": ")", "start": 160, "end": 161, "id": 30}, {"text": "swine", "start": 162, "end": 167, "id": 31}, {"text": "kidneys", "start": 168, "end": 175, "id": 32}, {"text": ".", "start": 175, "end": 176, "id": 33}, {"text": "Cortical", "start": 177, "end": 185, "id": 34}, {"text": "and", "start": 186, "end": 189, "id": 35}, {"text": "medullary", "start": 190, "end": 199, "id": 36}, {"text": "hypoxic", "start": 200, "end": 207, "id": 37}, {"text": "(", "start": 208, "end": 209, "id": 38}, {"text": "red", "start": 209, "end": 212, "id": 39}, {"text": ")", "start": 212, "end": 213, "id": 40}, {"text": "regions", "start": 214, "end": 221, "id": 41}, {"text": "are", "start": 222, "end": 225, "id": 42}, {"text": "observed", "start": 226, "end": 234, "id": 43}, {"text": "in", "start": 235, "end": 237, "id": 44}, {"text": "the", "start": 238, "end": 241, "id": 45}, {"text": "poststenotic", "start": 242, "end": 254, "id": 46}, {"text": "kidney", "start": 255, "end": 261, "id": 47}, {"text": ".", "start": 261, "end": 262, "id": 48}]}
{"pdf_hash": "2d0c0d335db89d9bc7f2e489d51afbc330958e0e", "fig_key": "Figure2", "fig_uri": "16-Figure2-1.png", "text": "Fig. 2. Bathypolypus bairdii (a) Transmission electron micrograph of the neck (Ne) and middle piece (MP), 365 showing the nuclear fossa (NF) which connects with the centriolar fossa (CF) via a small lumen (L). The chromatin (Cr) is projected on the neck forming the nuclear invagination (NI). The middle piece is marked by the beginning of the mitochondrial sheath (MS) and the fibrous sheath (FS). Asterisk show electron dense spheroid. Ax, axoneme; C, centriole; CFi coarse fibers; NM, nuclear membrane; PM, plasma membrane. Bar 300 nm. (b) Transmission electron micrograph of a cross section through the line represented in Fig. 2a, showing the centriolar fossa (CF), the coarse 370 fibers (CFi) partially defined, the central doublet (arrowheads) and the axoneme-coarse fibers complex (ACF). Cr, chromatin; NM, nuclear membrane; PM, plasma membrane. Bar 100 nm. (c) Transmission electron micrograph of the middle piece in cross section showing the mitochondria (M), the fibrous sheath (FS), the inner mitochondrial membrane (arrowhead) and the electron dense spheroid (asterisk). CFi, coarse fibers; PM, plasma membrane. Bar 200 nm. (d) Scanning electron micrograph of the neck (Ne), middle piece (MP) and annulus (An). Note the enlarged 375 mitochondria (arrowheads). 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{"pdf_hash": "cd46e232f7b306cdfd108302e9e7e887021bb1c9", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Colonic polyp. A: A sigmoid flat polyp was viewed using digital chromoendoscopy with high definition by i-scan, which revealed a pit pattern suggestive of a hyperplastic lesion in a patient with cirrhosis and important coagulation disorders; B: CLE showing dysplasia (image optimized by using a green-white image color palette in Cellvizio \u00ae viewer software); C: A histological analysis of the specimen confirmed the dysplasia. 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{"pdf_hash": "93f154a10fdb0b977f475747b48d3d9404f09057", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. 55-year-old woman with repaired tendon that changed from type I to type III during follow-up period. A. Supraspinatus tendon shows type I pattern with fluid-like bright high signal intensity (SI) foci (thick arrow) on oblique coronal T2-weighted images 5 months after surgery. Linear or curvilinear structures with intermediate to low SI, which appeared to be suture material, are detected within high SI area at repair site (thin arrows). B. 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{"pdf_hash": "cc2e8bd58a5d9efa7ff6052cf6d3296425e54952", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 MTR image processing. (A) NAWM from two 5 mm axial slices were extracted at (B) and immediately below (C) the level of the insula. Rings of concentric MTR values from the NAWM around the ventricles were then extracted (D and E). 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{"pdf_hash": "ea0edb780ccb1142565a7302d85b4cbc6c5f3cd9", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig 1. T2-weighted 3D coronal MRI. A- Landmarks for identification of STN (subthalamic nucleus): 14 to 18 mm posterior to AC (anterior commissure); superior and medial to the apex of the choroidal fissure; superior and lateral to SNR (substantia nigra pars reticulata); superior, lateral and anterior to RN (red nucleus); and an imaginary line passing through the lateral border of the brainstem usually crosses STN through its medial region; B- Habitual characteristics of the early-phase STN radiofrequency (RF) lesion: a three-concentriczone image; C- Unusual characteristics of the early-phase STN RF lesion: a hyperintense image, probably correlated with a poor outcome (only our two patients harboring such a lesion presented recurrence). 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{"pdf_hash": "767ab25445c483c7a229a4fcbbfa927e701e1d54", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Anatomy of the tessellated lower jaw skeleton of batoid elasmobranch fish (stingrays and relatives); lettered and inset red boxes reference other panels in the figure (e.g. the box in panel A references panel B). Elasmobranch skeletal elements are tiled superficially with abutting mineralized blocks called tesserae (T) (panel A: microCT scan, left lateral view; panel B: cleared and stained tissue), overlain by a fibrous perichondrium (PC) and surmounting a monolithic core of uncalcified cartilage (UC; panel C: cryoSEM cross-section). Note the camera view is somewhat oblique in panel C; tesserae can be seen in cross-section [T(c)] at the top of the image and in surface view [T(s)], covered by perichondrium, at the bottom. This sample was incompletely etched and from a young histotroph animal (79 mm); tesserae are less distinct than in other preparations (see Methods). At higher magnifications (panels D, E: hematoxylin-eosin stained cross-sections), the margins of tesserae are less regular and vital chondrocytes (CH) can be seen in mineralized lacunae in tesserae and extending into the intertesseral fibrous joints (IT). The tessellated skeleton can therefore be thought of simply as unmineralized cartilage wrapped in a composite fibro-mineral bark (panel F: schematic cross-section; black arrows indicate dimensions used to determine tesseral width and depth, see Methods).", "width": 856, "height": 1046, "subcaptions": {"a": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105], "b": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105], "c": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 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{"pdf_hash": "4d1d9c77a65ae934ad2e6b2d5cc31e7cf89de334", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Examples of HRP injection sites in the nucleus raphe magnus. A, Coronal brain section illustrating the size of the HRP deposit from case R-251 in which an iontophoretic injection of HRP was made into the raphe magnus (arrow). B, Coronal section through the rostra1 medulla depicting the size of the injection site (arrow) from case R-381 following a pressure injection of HRP in the raphe magnus. Some spread of the enzyme tracer is evident in the area dorsal to the raphe magnus.", "width": 1144, "height": 1364, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "b": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94]}, "subfigures": [{"id": "2dd6576e-d938-496b-9bf9-51ea1005f183", "label": "a", "points": [[17.2, 39.8], [17.2, 773.5], [1112.4, 773.5], [1112.4, 39.8]], "color": "yellow"}, {"id": "f5883c77-1432-42ae-8c73-72f0dd7c857d", "label": "b", "points": [[20.8, 797], [20.8, 1337.4], [1114.2, 1337.4], [1114.2, 797]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Examples", "start": 10, "end": 18, "id": 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{"pdf_hash": "bf492e480e1fca13eb8790ff528622507f9adb5c", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Figure 1. a, Nuclear reactivity for HMGI-C in the neoplastic adipocytes of a lipoma (case 17L); t(2;12)(q35;q15) was identified in the tumor karyotype, FISH analysis was not performed. b, The corresponding immunohistochemical stain for HMGI(Y) is negative (case 17L). c, Positive nuclear reactivity for HMGI(Y) in the mesenchymal cells of a pulmonary chondroid hamartoma (case 11P); t(6;10)(p21.3;q22.3) was identified in the tumor karyotype (Fig. 2d), FISH analysis results are illustrated in Figure 2c and are compatible with HMGI(Y) gene rearrangement. d, The corresponding immunohistochemical stain for HMGI(Y) is negative (case 11P). e, Nuclear reactivity for HMGI(Y) in the neoplastic smooth muscle cells of an uterine leiomyoma (case 1M); t(6;14)(p21;q24) was identified in the tumor karyotype; FISH analysis results are compatible with HMGI(Y) gene rearrangement. f, The corresponding immunohistochemical stain for HMGI-C is negative (case 1M). g, Nuclear reactivity for HMGI-C in the stromal component of an endometrial polyp (case 10E); t(12;14)(q15;q24\u201325) was identified in the tumor karyotype; FISH analysis results are compatible with HMGI-C gene rearrangement. 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{"pdf_hash": "d9f2948a0e3e18672cf194f05d3ee695759b96ca", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5 Electron microscope evidence for necrotic cell death in murine cortical cultures exposed to 60 min OGD. (A) Control healthy neurons showing nuclei with dispersed chromatin and a clearly defined nucleolus. A glial cell can be detected at the bottom-left corner of the microphotograph. (B) Six h after OGD, two well preserved neurons together with a shrinked, damaged neuron (asterisk). (C) Enlarged microphotograph of the same damaged neuron shown in B, rotated clockwise by 908 with the asterisk in the same position, displaying signs of necrotic degeneration. Chromatin is condensing, the nuclear and plasma membranes are disrupted, the cytoplasm is dispersed and contains vacuoles and swollen organelles. (D) Another enlarged neuron observed 6 h after 60 min OGD, showing necrotic features such as clumped chromatin, amorphous organelles, mitochondrial densities and cytoplasm disorganization. (E) Twenty-four h after 60 min OGD, only healthy and isolated glial cells can be detected. 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{"pdf_hash": "394b7569ded5954467b6ebc4557e516bbfbcd268", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. (a) MRI Head (T2 weighted) showing severe ethmoid sinusitis (unmarked). (b) MRI Head (T2 weighted) showing severe ethmoid sinusitis (marked).", "width": 694, "height": 1528, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "6302bbb8-1e1b-4e8b-a25f-61cb2a481c42", "label": "a", "points": [[47.7, 2], [47.7, 726.7], [674.8, 726.7], [674.8, 2]], "color": "yellow"}, {"id": "74a1248d-ba5b-440a-a2cf-3a81080b5199", "label": "b", "points": [[46.6, 763.4], [46.6, 1496.8], [678.1, 1496.8], [678.1, 763.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "a", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "MRI", "start": 12, "end": 15, "id": 7}, {"text": "Head", "start": 16, "end": 20, "id": 8}, {"text": "(", "start": 21, "end": 22, "id": 9}, {"text": "T2", "start": 22, "end": 24, "id": 10}, {"text": "weighted", "start": 25, "end": 33, "id": 11}, {"text": ")", "start": 33, "end": 34, "id": 12}, {"text": "showing", "start": 35, "end": 42, "id": 13}, {"text": "severe", "start": 43, "end": 49, "id": 14}, {"text": "ethmoid", "start": 50, "end": 57, "id": 15}, {"text": "sinusitis", "start": 58, "end": 67, "id": 16}, {"text": "(", "start": 68, "end": 69, "id": 17}, {"text": "unmarked", "start": 69, "end": 77, "id": 18}, {"text": ")", "start": 77, "end": 78, "id": 19}, {"text": ".", "start": 78, "end": 79, "id": 20}, {"text": "(", "start": 80, "end": 81, "id": 21}, {"text": "b", "start": 81, "end": 82, "id": 22}, {"text": ")", "start": 82, "end": 83, "id": 23}, {"text": "MRI", "start": 84, "end": 87, "id": 24}, {"text": "Head", "start": 88, "end": 92, "id": 25}, {"text": "(", "start": 93, "end": 94, "id": 26}, {"text": "T2", "start": 94, "end": 96, "id": 27}, {"text": "weighted", "start": 97, "end": 105, "id": 28}, {"text": ")", "start": 105, "end": 106, "id": 29}, {"text": "showing", "start": 107, "end": 114, "id": 30}, {"text": "severe", "start": 115, "end": 121, "id": 31}, {"text": "ethmoid", "start": 122, "end": 129, "id": 32}, {"text": "sinusitis", "start": 130, "end": 139, "id": 33}, {"text": "(", "start": 140, "end": 141, "id": 34}, {"text": "marked", "start": 141, "end": 147, "id": 35}, {"text": ")", "start": 147, "end": 148, "id": 36}, {"text": ".", "start": 148, "end": 149, "id": 37}]}
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{"pdf_hash": "1418e0734a2fe01d87678da9275edffc12cde282", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 In situ analysis of TDG transcript distribution in 14.5 d.p.c. mouse fetuses. All panels are composed of a bright-\u00aeeld view of a selected section, showing the histology, and of the corresponding dark-\u00aeeld view where the signal grain appears in white. (a) General view of a 14.5 d.p.c. fetus sectioned sagittally. (b) Sagittal section through the developing hindlimb. (c) Sagittal section through the lung and thymus. (d) Enlargement of two intestinal loops. Abbreviations: a: adrenal gland; bl: urinary bladder; br: stem bronchus; c: cartilage; ep: intestinal epithelium; fb: forebrain; hb: hindbrain; ht: heart; in: intestine; k: kidney; li: liver; lu: lung; m: muscle; mb: midbrain; mc: mouth cavity; me: intestinal mesenchyme; ne: nasal epithelium; pi: pituitary gland (anterior lobe); sg: spinal ganglia; th: thymus", "width": 1044, "height": 1502, "subcaptions": {"a": [65, 66, 67, 68, 69, 70, 71, 72, 73, 74], "b": [75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85], "c": [86, 87, 88, 89, 90, 91, 92, 93]}, "subfigures": [{"id": "0c6f1fb6-733e-41c8-9e72-571233974488", "label": "a", "points": [[41.5, 1.6], [41.5, 720.7], [521.5, 720.7], [521.5, 1.6]], "color": "yellow"}, {"id": "57fa300e-26f7-4d2e-8691-08251a661444", "label": "a", "points": [[542.9, 4.9], [542.9, 724], [1017.9, 724], [1017.9, 4.9]], "color": "cyan"}, {"id": "711edf6c-c1a0-4e4f-b113-8c567579657e", "label": "b", "points": [[48.1, 738.9], [48.1, 1172.7], [442.3, 1172.7], [442.3, 738.9]], 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{"pdf_hash": "f36db66068a9e46093a04572da630d99b3064d9a", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. Computed tomography (CT). (A) Pectoral CT reveals a large, heterogeneous tumorous formation obturating the esophageal lumen, with no enlarged lymph node observed, located in the same plane as the lower tracheal bifurcation. The value of CT is ~78 Hu. (B) The abdominal CT reveals the nodular increased thickness of the gastric antral wall and the narrowing gastric cavity.", "width": 690, "height": 254, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "b": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73]}, "subfigures": [{"id": "57607250-82b5-489d-9dcc-43e92883e257", "label": "a", "points": [[3.8, 7.6], [3.8, 247.4], [342.8, 247.4], [342.8, 7.6]], "color": "yellow"}, {"id": "f7e6a7b7-f45a-45a9-ae59-3e5c5ae76d6e", "label": "b", "points": [[347.2, 4.4], [347.2, 246.4], [677.5, 246.4], [677.5, 4.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Computed", "start": 10, "end": 18, "id": 3}, {"text": "tomography", "start": 19, "end": 29, "id": 4}, {"text": "(", "start": 30, "end": 31, "id": 5}, {"text": "CT", "start": 31, "end": 33, "id": 6}, {"text": ")", "start": 33, "end": 34, "id": 7}, {"text": ".", "start": 34, "end": 35, "id": 8}, {"text": "(", "start": 36, "end": 37, "id": 9}, {"text": "A", "start": 37, "end": 38, "id": 10}, {"text": ")", "start": 38, "end": 39, "id": 11}, {"text": "Pectoral", "start": 40, "end": 48, "id": 12}, {"text": "CT", "start": 49, "end": 51, "id": 13}, {"text": "reveals", "start": 52, "end": 59, "id": 14}, {"text": "a", "start": 60, "end": 61, "id": 15}, {"text": "large", "start": 62, "end": 67, "id": 16}, {"text": ",", "start": 67, "end": 68, "id": 17}, {"text": "heterogeneous", "start": 69, "end": 82, "id": 18}, {"text": "tumorous", "start": 83, "end": 91, "id": 19}, {"text": "formation", "start": 92, "end": 101, "id": 20}, {"text": "obturating", "start": 102, "end": 112, "id": 21}, {"text": "the", "start": 113, "end": 116, "id": 22}, {"text": "esophageal", "start": 117, "end": 127, "id": 23}, {"text": "lumen", "start": 128, "end": 133, "id": 24}, {"text": ",", "start": 133, "end": 134, "id": 25}, {"text": "with", "start": 135, "end": 139, "id": 26}, {"text": "no", "start": 140, "end": 142, "id": 27}, {"text": "enlarged", "start": 143, "end": 151, "id": 28}, {"text": "lymph", "start": 152, "end": 157, "id": 29}, {"text": "node", "start": 158, "end": 162, "id": 30}, {"text": "observed", "start": 163, "end": 171, "id": 31}, {"text": ",", "start": 171, "end": 172, "id": 32}, {"text": "located", "start": 173, "end": 180, "id": 33}, {"text": "in", "start": 181, "end": 183, "id": 34}, {"text": "the", "start": 184, "end": 187, "id": 35}, {"text": "same", "start": 188, "end": 192, "id": 36}, {"text": "plane", "start": 193, "end": 198, "id": 37}, {"text": "as", "start": 199, "end": 201, "id": 38}, {"text": "the", "start": 202, "end": 205, "id": 39}, {"text": "lower", "start": 206, "end": 211, "id": 40}, {"text": "tracheal", "start": 212, "end": 220, "id": 41}, {"text": "bifurcation", "start": 221, "end": 232, "id": 42}, {"text": ".", "start": 232, "end": 233, "id": 43}, {"text": "The", "start": 234, "end": 237, "id": 44}, {"text": "value", "start": 238, "end": 243, "id": 45}, {"text": "of", "start": 244, "end": 246, "id": 46}, {"text": "CT", "start": 247, "end": 249, "id": 47}, {"text": "is", "start": 250, "end": 252, "id": 48}, {"text": "~78", "start": 253, "end": 256, "id": 49}, {"text": "Hu", "start": 257, "end": 259, "id": 50}, {"text": ".", "start": 259, "end": 260, "id": 51}, {"text": "(", "start": 261, "end": 262, "id": 52}, {"text": "B", "start": 262, "end": 263, "id": 53}, {"text": ")", "start": 263, "end": 264, "id": 54}, {"text": "The", "start": 265, "end": 268, "id": 55}, {"text": "abdominal", "start": 269, "end": 278, "id": 56}, {"text": "CT", "start": 279, "end": 281, "id": 57}, {"text": "reveals", "start": 282, "end": 289, "id": 58}, {"text": "the", "start": 290, "end": 293, "id": 59}, {"text": "nodular", "start": 294, "end": 301, "id": 60}, {"text": "increased", "start": 302, "end": 311, "id": 61}, {"text": "thickness", "start": 312, "end": 321, "id": 62}, {"text": "of", "start": 322, "end": 324, "id": 63}, {"text": "the", "start": 325, "end": 328, "id": 64}, {"text": "gastric", "start": 329, "end": 336, "id": 65}, {"text": "antral", "start": 337, "end": 343, "id": 66}, {"text": "wall", "start": 344, "end": 348, "id": 67}, {"text": "and", "start": 349, "end": 352, "id": 68}, {"text": "the", "start": 353, "end": 356, "id": 69}, {"text": "narrowing", "start": 357, "end": 366, "id": 70}, {"text": "gastric", "start": 367, "end": 374, "id": 71}, {"text": "cavity", "start": 375, "end": 381, "id": 72}, {"text": ".", "start": 381, "end": 382, "id": 73}]}
{"pdf_hash": "8b1252c6941bc5cb4d02c6e86556084496eb6a74", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Figure 5. Oligodendrocytes, their processes, and nodes of Ranvier are associated with the reticular astrocyte network. u, Transverse EM section, showing an oligodendrocyte (0) and its process (p) running apposed to reticular astrocytic profiles (n). x 16,000. b, Transverse section showing a neighbor pair of nodes (N, top right), one touched (Table 1) by a reticular astrocyte process (p). The subaxolemmal density of nodes distinguished them from unmyelinated fibers (u, left). x 32,000. c and d, Examples from the spectrum of pet-modal astrocytic processes observed; see Table 1. pn, paranode; other labels as above. x 5 1,000. e, Longitudinal section through a representative node, with a reticular astrocyte process to the right. 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{"pdf_hash": "df3e7003f0ca7411783d6bb807cd6ae15043be27", "fig_key": "Figure2", "fig_uri": "1-Figure2-1.png", "text": "Figure 2 Sagittal T1-weighted (left) and coronal T2-weighted (right) images demonstrating a spaceoccupying lesion in the left cerebellopontine angle compressing the brainstem and vestibulocerebellum.", "width": 548, "height": 312, "subcaptions": {"a": [2, 3, 4, 5, 6], "b": [8, 9, 10, 11, 12]}, "subfigures": [{"id": "047ee31b-fff3-42b1-811e-f4728d15d680", "label": "a", "points": [[2, 3], [2, 278], [268, 278], [268, 3]], "color": "yellow"}, {"id": "536f7a86-7d36-4b0c-bbcd-a4a9051e5f6a", "label": "b", "points": [[271, 0], [271, 278], [546, 278], [546, 0]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Sagittal", "start": 9, "end": 17, "id": 2}, {"text": "T1-weighted", "start": 18, "end": 29, "id": 3}, {"text": "(", "start": 30, "end": 31, "id": 4}, {"text": "left", "start": 31, "end": 35, "id": 5}, {"text": ")", "start": 35, "end": 36, "id": 6}, {"text": "and", "start": 37, "end": 40, "id": 7}, {"text": "coronal", "start": 41, "end": 48, "id": 8}, {"text": "T2-weighted", "start": 49, "end": 60, "id": 9}, {"text": "(", "start": 61, "end": 62, "id": 10}, {"text": "right", "start": 62, "end": 67, "id": 11}, {"text": ")", "start": 67, "end": 68, "id": 12}, {"text": "images", "start": 69, "end": 75, "id": 13}, {"text": "demonstrating", "start": 76, "end": 89, "id": 14}, {"text": "a", "start": 90, "end": 91, "id": 15}, {"text": "spaceoccupying", "start": 92, "end": 106, "id": 16}, {"text": "lesion", "start": 107, "end": 113, "id": 17}, {"text": "in", "start": 114, "end": 116, "id": 18}, {"text": "the", "start": 117, "end": 120, "id": 19}, {"text": "left", "start": 121, "end": 125, "id": 20}, {"text": "cerebellopontine", "start": 126, "end": 142, "id": 21}, {"text": "angle", "start": 143, "end": 148, "id": 22}, {"text": "compressing", "start": 149, "end": 160, "id": 23}, {"text": "the", "start": 161, "end": 164, "id": 24}, {"text": "brainstem", "start": 165, "end": 174, "id": 25}, {"text": "and", "start": 175, "end": 178, "id": 26}, {"text": "vestibulocerebellum", "start": 179, "end": 198, "id": 27}, {"text": ".", "start": 198, "end": 199, "id": 28}]}
{"pdf_hash": "330f8a069605a8d246c30651af2dc4460c43431e", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Fig 2. Thymosin-\u03b24 is not co-localised with MHC in the ventricle wall. Fluorescent immunostaining of foetal heart sections dual stained for thymosin \u03b24 (A & E) and MHC (B & F), a cardiomyocyte marker, at low (A-D) and high (E-H) magnification. DAPI nuclear staining is also shown (C & G). Thymosin \u03b24 staining is distinct from MHC staining (H). Representative of six individual hearts (7-12 pcw). 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{"pdf_hash": "1a4575ccb88287ae8646d9e393d262ce30560987", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. A 54-year-old female patient admitted with the complaints of severe neck pain weakness at all four extremities and numbness particularly in the upper extremities. Her Nurick grade was 1 preoperatively. Her contrast-enhanced cervical magnetic resonance imaging (MRI) revealed about a 2.5 cm mass lesion in the neural channel with a typical meningioma view of a dural tail at the C1 level (sagittal [A] and axial [B] views with contrast). 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{"pdf_hash": "37122967788dd01176a33faf0538e72b71a35215", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Fig. 3. Group\u00d7neural: negatively valenced distraction interactions. The figures show axial s deactivations in purple/blue. The color bars indicate the voxel-wise t statistic. Neural: cognit controls, a group\u00d7neural: negatively valence distraction interaction was detected in the righ driven by greater deactivation in the right mPFC in the unmedicated ADHD sample as comp identified in the mPFC bilaterally when examining the medicated and unmedicated ADHD unmedicated as compared to mediated ADHD sample. 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{"pdf_hash": "d08e28dfcea5ff09ba469ef80e8185d37360d89e", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Non-small Cell Lung Cancer FDG PET-CT Imaging Features. A three dimensional, maximum intensity projection, whole body 18F-FDG PET-CT (left). Physiologic uptake is seen in the brain, heart and liver with excretion through the renal pelvis and bladder. This tumor showed an intense FDG uptake with SUVmax of 19, SUVmean of 9.6, and TLG of 65.6 using a 50% SUVmax threshold (upper right). 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{"pdf_hash": "9a6a4ae39374fd32ffe0bd7fe0e313e72fa49526", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2 Experimental pain paradigm and functional connectivity results. The schematic illustration (A) represents the experimental pressure pain paradigm used during fMRI scanning. Calibrated painful pressures (long lines), representing 50 mm VAS, and non-painful pressures (short lines) were randomly delivered to the thumbnail during 2 adjacent 8 minute runs with 20 painful and 10 non-painful stimuli in each run. Functional connectivity results for the rACC seed (B) revealed incraesed connectivity to the amygdala (peak coordinate x = \u221214, y = 0, = \u2212 16) and a cluster encompassing the brainstem/PAG/hippocampus (peak coordinate x = 12, y = 24, z = \u221212) in healthy controls, comapred to FM patients. 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{"pdf_hash": "56a5c4b9d488f0b5f2ef4d3745b73bbe0b6ffa0a", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. (A) Complete hydatidiform mole (CHM): irregular villous outline (club shaped) with villous stromal karyorrhectic debris. (B) Partial hydatidiform mole (PHM). Two villous populations; large edematous villi with irregular outline and normal appearing nondistended ones. (C) Hydropic abortion (HA): distended villi with hydropic change. (D) CHM: trophoblastic inclusion (arrow). (E) CHM: cistern formation. (F) CHM: multifocal villous trophoblastic hyperplasia. (G) HA: positive p57Kip2 nuclear staining in intermediate trophoblast as positive internal control (asterisk). Positive p57Kip2 nuclear staining in villous cytotrophoblasts (CT) (short arrow) and villous stromal cells (long arrow) (immunoperoxidase). (H) CHM p57Kip2 immunohistochemistry: negative nuclear staining in villous CT (short arrow) and villous stromal cells (long arrow); positive p57Kip2 nuclear staining in intermediate trophoblast as positive internal control (asterisk) (immunoperoxidase). 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{"pdf_hash": "b3444c38934607753dc9b096dc2049f0f657d72f", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. T 2 weighted MR images at the level of the pons (a) and at the level of the mesencephalon (b) at first presentation in 2011 (first row), at second presentation in 2013 (second row) and at time of diagnosis in 2015 (third row). In 2015, an abnormal T 2 hyperintense signal is seen on the dorsolateral side of the fourth ventricle (arrows), with little mass effect. 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{"pdf_hash": "ceceb80730e02ebec807061ace6346109b7a6a4d", "fig_key": "Figure12", "fig_uri": "8-Figure12-1.png", "text": "Fig. 12. Partial tear of undersurface of supraspinatus tendon with SGHL tear in 47-year-old man. A. Oblique coronal fat-saturated T1-weighted MR arthrographic image shows partial tear of undersurface of supraspinatus tendon (white arrowheads). B, C. Oblique sagittal and oblique coronal fat-saturated T1-weighted MR arthrographic images show SGHL tear (black arrow). 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{"pdf_hash": "f51c723ce71db9ab319d51bc2b0f70a485846dd2", "fig_key": "Figure4", "fig_uri": "11-Figure4-1.png", "text": "FIGURE 4. Immunostaining results of UB-MNAC. A, Uniform nuclear GATA3 expression. B, Diffuse and strong nuclear PAX2 immunoreactivity. C, Preserved PTEN expression. D, Lack of ER expression. E, Lack of PR expression. F, Wild-type p53 immunostaining pattern. G, Focal p16 expression. H, Uniform CD10 immunoreactivity along the luminal surface. 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{"pdf_hash": "1e6a1c7d13676b5ba6d5b16c27c89b5af0b70f61", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Contrast-enhanced computed tomography scan (A, transverse view; B, coronal view) images demonstrate a tumor (arrowheads) protruding into the esophageal lumen. The large tumor is almost completely obstructing the esophagus.", "width": 1174, "height": 582, "subcaptions": {"a": [11, 12, 13, 14, 15], "b": [16, 17, 18, 19]}, "subfigures": [{"id": "054a27b5-b43d-4351-b50f-432f93570829", "label": "a", "points": [[33.7, 1.2], [33.7, 557.7], [580.8, 557.7], [580.8, 1.2]], "color": "yellow"}, {"id": "0be65841-2873-484e-8f4b-edec211d7c42", "label": "b", "points": [[593.8, 1.2], [593.8, 559.5], [1141, 559.5], [1141, 1.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Contrast", "start": 8, "end": 16, "id": 4}, {"text": "-", "start": 16, "end": 17, "id": 5}, {"text": "enhanced", "start": 17, "end": 25, "id": 6}, {"text": "computed", "start": 26, "end": 34, "id": 7}, {"text": "tomography", "start": 35, "end": 45, "id": 8}, {"text": "scan", "start": 46, "end": 50, "id": 9}, {"text": "(", "start": 51, "end": 52, "id": 10}, {"text": "A", "start": 52, "end": 53, "id": 11}, {"text": ",", "start": 53, "end": 54, "id": 12}, {"text": "transverse", "start": 55, "end": 65, "id": 13}, {"text": "view", "start": 66, "end": 70, "id": 14}, {"text": ";", "start": 70, "end": 71, "id": 15}, {"text": "B", "start": 72, "end": 73, "id": 16}, {"text": ",", "start": 73, "end": 74, "id": 17}, {"text": "coronal", "start": 75, "end": 82, "id": 18}, {"text": "view", "start": 83, "end": 87, "id": 19}, {"text": ")", "start": 87, "end": 88, "id": 20}, {"text": "images", "start": 89, "end": 95, "id": 21}, {"text": "demonstrate", "start": 96, "end": 107, "id": 22}, {"text": "a", "start": 108, "end": 109, "id": 23}, {"text": "tumor", "start": 110, "end": 115, "id": 24}, {"text": "(", "start": 116, "end": 117, "id": 25}, {"text": "arrowheads", "start": 117, "end": 127, "id": 26}, {"text": ")", "start": 127, "end": 128, "id": 27}, {"text": "protruding", "start": 129, "end": 139, "id": 28}, {"text": "into", "start": 140, "end": 144, "id": 29}, {"text": "the", "start": 145, "end": 148, "id": 30}, {"text": "esophageal", "start": 149, "end": 159, "id": 31}, {"text": "lumen", "start": 160, "end": 165, "id": 32}, {"text": ".", "start": 165, "end": 166, "id": 33}, {"text": "The", "start": 167, "end": 170, "id": 34}, {"text": "large", "start": 171, "end": 176, "id": 35}, {"text": "tumor", "start": 177, "end": 182, "id": 36}, {"text": "is", "start": 183, "end": 185, "id": 37}, {"text": "almost", "start": 186, "end": 192, "id": 38}, {"text": "completely", "start": 193, "end": 203, "id": 39}, {"text": "obstructing", "start": 204, "end": 215, "id": 40}, {"text": "the", "start": 216, "end": 219, "id": 41}, {"text": "esophagus", "start": 220, "end": 229, "id": 42}, {"text": ".", "start": 229, "end": 230, "id": 43}]}
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{"pdf_hash": "ccbf14006c9355047861afaa7764d95781204bad", "fig_key": "Figure19", "fig_uri": "20-Figure19-1.png", "text": "Figure 19. Tubulanus polymorphus, confocal laserscanning (cLSM) micrographs of differently immunostained vibratome sections. a: Transverse section, anti-FMRF (red), anti-a-tubulin (green) showing the subepidermal (snp) and the stomatogastric (sgp) nerve plexus. b: Horizontal section, anti-FMRF showing the regular arranged neurites (ne) of the subepidermal nerve plexus. c: Horizontal section, anti-FMRF. The neurites (ne) of the intrastomatogastric nerve plexus (isgp) are arranged in a regular ladder-like fashion. d: Transverse section, anti-serotonin. The lateral medullary cords (mc) are interconnected by a commissural plexus (cnp). 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{"pdf_hash": "d68cab79c593ddd0abf35045ebdca24053a89d5d", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Patterns of the SMA boundary in the arterial phase on preoperative abdominal contrast-enhanced computed tomography. The short red arrows indicate the SMA, the long red arrows indicate tissues in the SMA margin, and the black circles indicate pancreatic head adenocarcinoma. (A) Obscure SMA boundary. (B) Clear SMA boundary. SMA, superior mesenteric artery.", "width": 684, "height": 1032, "subcaptions": {"a": [49, 50, 51, 52, 53, 54, 55], "b": [56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "3d19423a-c102-44ac-8143-1ef64ec41504", "label": "a", "points": [[62.7, 8.6], [62.7, 486.3], [677.5, 486.3], [677.5, 8.6]], "color": "yellow"}, {"id": "b56201dd-747a-44d6-91fe-065279ea421e", "label": "b", "points": [[61.6, 516.5], [61.6, 992], [678.6, 992], [678.6, 516.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Patterns", "start": 10, "end": 18, "id": 3}, {"text": "of", "start": 19, "end": 21, "id": 4}, {"text": "the", "start": 22, "end": 25, "id": 5}, {"text": "SMA", "start": 26, "end": 29, "id": 6}, {"text": "boundary", "start": 30, "end": 38, "id": 7}, {"text": "in", "start": 39, "end": 41, "id": 8}, {"text": "the", "start": 42, "end": 45, "id": 9}, {"text": "arterial", "start": 46, "end": 54, "id": 10}, {"text": "phase", "start": 55, "end": 60, "id": 11}, {"text": "on", "start": 61, "end": 63, "id": 12}, {"text": "preoperative", "start": 64, "end": 76, "id": 13}, {"text": "abdominal", "start": 77, "end": 86, "id": 14}, {"text": "contrast", "start": 87, "end": 95, "id": 15}, {"text": "-", "start": 95, "end": 96, "id": 16}, {"text": "enhanced", "start": 96, "end": 104, "id": 17}, {"text": "computed", "start": 105, "end": 113, "id": 18}, {"text": "tomography", "start": 114, "end": 124, "id": 19}, {"text": ".", "start": 124, "end": 125, "id": 20}, {"text": "The", "start": 126, "end": 129, "id": 21}, {"text": "short", "start": 130, "end": 135, "id": 22}, {"text": "red", "start": 136, "end": 139, "id": 23}, {"text": "arrows", "start": 140, "end": 146, "id": 24}, {"text": "indicate", "start": 147, "end": 155, "id": 25}, {"text": "the", "start": 156, "end": 159, "id": 26}, {"text": "SMA", "start": 160, "end": 163, "id": 27}, {"text": ",", "start": 163, "end": 164, "id": 28}, {"text": "the", "start": 165, "end": 168, "id": 29}, {"text": "long", "start": 169, "end": 173, "id": 30}, {"text": "red", "start": 174, "end": 177, "id": 31}, {"text": "arrows", "start": 178, "end": 184, "id": 32}, {"text": "indicate", "start": 185, "end": 193, "id": 33}, {"text": "tissues", "start": 194, "end": 201, "id": 34}, {"text": "in", "start": 202, "end": 204, "id": 35}, {"text": "the", "start": 205, "end": 208, "id": 36}, {"text": "SMA", "start": 209, "end": 212, "id": 37}, {"text": "margin", "start": 213, "end": 219, "id": 38}, {"text": ",", "start": 219, "end": 220, "id": 39}, {"text": "and", "start": 221, "end": 224, "id": 40}, {"text": "the", "start": 225, "end": 228, "id": 41}, {"text": "black", "start": 229, "end": 234, "id": 42}, {"text": "circles", "start": 235, "end": 242, "id": 43}, {"text": "indicate", "start": 243, "end": 251, "id": 44}, {"text": "pancreatic", "start": 252, "end": 262, "id": 45}, {"text": "head", "start": 263, "end": 267, "id": 46}, {"text": "adenocarcinoma", "start": 268, "end": 282, "id": 47}, {"text": ".", "start": 282, "end": 283, "id": 48}, {"text": "(", "start": 284, "end": 285, "id": 49}, {"text": "A", "start": 285, "end": 286, "id": 50}, {"text": ")", "start": 286, "end": 287, "id": 51}, {"text": "Obscure", "start": 288, "end": 295, "id": 52}, {"text": "SMA", "start": 296, "end": 299, "id": 53}, {"text": "boundary", "start": 300, "end": 308, "id": 54}, {"text": ".", "start": 308, "end": 309, "id": 55}, {"text": "(", "start": 310, "end": 311, "id": 56}, {"text": "B", "start": 311, "end": 312, "id": 57}, {"text": ")", "start": 312, "end": 313, "id": 58}, {"text": "Clear", "start": 314, "end": 319, "id": 59}, {"text": "SMA", "start": 320, "end": 323, "id": 60}, {"text": "boundary", "start": 324, "end": 332, "id": 61}, {"text": ".", "start": 332, "end": 333, "id": 62}, {"text": "SMA", "start": 334, "end": 337, "id": 63}, {"text": ",", "start": 337, "end": 338, "id": 64}, {"text": "superior", "start": 339, "end": 347, "id": 65}, {"text": "mesenteric", "start": 348, "end": 358, "id": 66}, {"text": "artery", "start": 359, "end": 365, "id": 67}, {"text": ".", "start": 365, "end": 366, "id": 68}]}
{"pdf_hash": "995b7b9c7e181f176dfddf1b619540c815aa30dc", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. Histological findings of atypical carcinoid. (a) The tumor focally extends into the stromawith palisading of columnar cells and rosette-like structures. The cells had relatively abundant cytoplasm, oval nuclear pleomorphism, and irregularity (\u00d7400 hematoxylin\u2013 eosin). (b) Chromogranin A on immunohistochemical study (\u00d7200). (c) Synaptophysin on immunohistochemical study (\u00d7200). 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{"pdf_hash": "61265fd4e581127c13ccbaca6e3852ab72858eaf", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "FIGURE 6. Clinical utility of blood flow quantification. In this example, from 81-y-old man with hypertension and dyslipidemia, relative MPI (A) with 82 Rb PET demonstrated only mild, reversible perfusion abnormality involving distribution of left anterior descending coronary artery. However, MFR was severely reduced globally at 1.11. Nearly entire heart had severely reduced MFR except for inferior and inferolateral walls, where it was only moderately reduced. 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{"pdf_hash": "0cf4c33881b421e8b58106d6671e01ff50550a59", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1: Imaging data and the removed prostatic specimen. Preoperative (a and b) and postoperative (c and d) imaging data. CT (a) show that the whole pelvic cavity is occupied by a giant prostate. Urography (b) reveals passable filling of the bladder with no urethral stenosis, ectasia, or atresia. CT (c) re\u2011examinations show that the pelvic wound heals well and the bladder is in place. Cystoscopic urography (d) shows normal bladder containment with no urethral stenosis. (e) The final gross prostatectomy specimen measuring 11 cm \u00d7 13 cm. (f) The removed prostatic specimen weighing 524.2 g. 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(A) Computed tomography detected a 2 \u00d7 1.5 cm hypodense solid mass with an unclear margin in the head of the pancreas; (B) expanded primary pancreatic duct and the cystic low density in the tail of pancreas; (C) cystic low density in the uncinate process of the pancreas; (D) PET-CT revealed a malignant mass in the pancreatic head.", "width": 998, "height": 892, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "c": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65], "d": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80]}, "subfigures": [{"id": "30abaeb6-9de8-4f44-a00e-e72286f6cdb3", "label": "a", "points": [[26.1, 21.8], [26.1, 444.3], [483.3, 444.3], [483.3, 21.8]], "color": "yellow"}, {"id": "38b2cd22-a4d0-4c97-ba3d-16cacb95989d", "label": "b", "points": [[500.6, 25], [500.6, 445.9], [957.8, 445.9], [957.8, 25]], "color": 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{"pdf_hash": "f4868ba4248a4cef93d4a4d3511ae47763654a9f", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Preoperative MRI images showing the three types of burst fracture according to the Magerl classification system. (A) Superior-type patient with superior incomplete burst fracture (arrow). (B) Inferior-type patient with inferior incomplete burst fracture (arrow). (C) Complete-type patient with complete burst fracture (arrow). Arrowheads indicate regions of collapse. 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{"pdf_hash": "8e97a9afcea66154517fe1a1bb7a6318fe2fda89", "fig_key": "Figure10", "fig_uri": "10-Figure10-1.png", "text": "Fig. 10 Biphosphonate osteonecrosis. a OPT; b 3D reconstruction anteo-lateral view. Contrast-enhanced axial CT image with bone window settings (c) and soft tissue settings (d). Poorly defined osteolytic lesion of the left mandibular body (thick white arrows) with partly sclerotic margins (thin arrows in a) and large osseous defect (red arrows in b). 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{"pdf_hash": "132885913e9c8ab498ce8a2112587a625ac75b7f", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. (A) Preoperative kidney, ureter and bladder (KUB) radiograph of Case 1, showing two stones in the lower calyx of the left kidney (diameter 6-7 mm). (B) Preoperative computed tomography (CT) scan showing two stones in the lower calyx of the left kidney (diameter 6-7 mm). 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{"pdf_hash": "43e72f95777d246e3872c798c16966d9a4c0a284", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 MRI of this case. A significant cerebellar tonsillar hernia (a), Syringomyelia from C1 to T4 (b), disappearance of humeral head and swollen soft tissue of the surrounding of the joint (c and d).", "width": 1014, "height": 660, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14], "b": [16, 17, 18, 19, 20, 21, 22, 23], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 25, 26, 27, 28, 29, 30, 31], "d": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "9cc77c09-bcba-4eaa-9330-6e2c4eda1406", "label": "a", "points": [[40.3, 20.3], [40.3, 625.8], [362.3, 625.8], [362.3, 20.3]], "color": "yellow"}, {"id": "6f5c27c3-3bf4-4db3-bf23-5fbb7f7d1f69", "label": "b", "points": [[373.5, 21.9], [373.5, 622.6], [690.7, 622.6], [690.7, 21.9]], "color": "cyan"}, {"id": "51b0a336-b0de-413c-b0b2-5398f68bd7f2", "label": "c", "points": [[705.1, 18.7], [705.1, 323.1], [974.2, 323.1], [974.2, 18.7]], "color": "magenta"}, {"id": "121fbd13-be26-4a09-9111-349ae4c76203", "label": "d", "points": [[711.5, 332.7], [711.5, 625.8], [980.7, 625.8], [980.7, 332.7]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "MRI", "start": 9, "end": 12, "id": 2}, {"text": "of", "start": 13, "end": 15, "id": 3}, {"text": "this", "start": 16, "end": 20, "id": 4}, {"text": "case", "start": 21, "end": 25, "id": 5}, {"text": ".", "start": 25, "end": 26, "id": 6}, {"text": "A", "start": 27, "end": 28, "id": 7}, {"text": "significant", "start": 29, "end": 40, "id": 8}, {"text": "cerebellar", "start": 41, "end": 51, "id": 9}, {"text": "tonsillar", "start": 52, "end": 61, "id": 10}, {"text": "hernia", "start": 62, "end": 68, "id": 11}, {"text": "(", "start": 69, "end": 70, "id": 12}, {"text": "a", "start": 70, "end": 71, "id": 13}, {"text": ")", "start": 71, "end": 72, "id": 14}, {"text": ",", "start": 72, "end": 73, "id": 15}, {"text": "Syringomyelia", "start": 74, "end": 87, "id": 16}, {"text": "from", "start": 88, "end": 92, "id": 17}, {"text": "C1", "start": 93, "end": 95, "id": 18}, {"text": "to", "start": 96, "end": 98, "id": 19}, {"text": "T4", "start": 99, "end": 101, "id": 20}, {"text": "(", "start": 102, "end": 103, "id": 21}, {"text": "b", "start": 103, "end": 104, "id": 22}, {"text": ")", "start": 104, "end": 105, "id": 23}, {"text": ",", "start": 105, "end": 106, "id": 24}, {"text": "disappearance", "start": 107, "end": 120, "id": 25}, {"text": "of", "start": 121, "end": 123, "id": 26}, {"text": "humeral", "start": 124, "end": 131, "id": 27}, {"text": "head", "start": 132, "end": 136, "id": 28}, {"text": "and", "start": 137, "end": 140, "id": 29}, {"text": "swollen", "start": 141, "end": 148, "id": 30}, {"text": "soft", "start": 149, "end": 153, "id": 31}, {"text": "tissue", "start": 154, "end": 160, "id": 32}, {"text": "of", "start": 161, "end": 163, "id": 33}, {"text": "the", "start": 164, "end": 167, "id": 34}, {"text": "surrounding", "start": 168, "end": 179, "id": 35}, {"text": "of", "start": 180, "end": 182, "id": 36}, {"text": "the", "start": 183, "end": 186, "id": 37}, {"text": "joint", "start": 187, "end": 192, "id": 38}, {"text": "(", "start": 193, "end": 194, "id": 39}, {"text": "c", "start": 194, "end": 195, "id": 40}, {"text": "and", "start": 196, "end": 199, "id": 41}, {"text": "d", "start": 200, "end": 201, "id": 42}, {"text": ")", "start": 201, "end": 202, "id": 43}, {"text": ".", "start": 202, "end": 203, "id": 44}]}
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{"pdf_hash": "99de8ef54da243ca5c09d6f74e3cc19d1863f5a3", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Breast Core Biopsy. (A) Low power: moderately differentiated invasive ductal carcinoma. The invasive tumor exhibits stromal desmoplasia and is composed of infiltrating small irregular solid nests of cells with absent glandular formation. (B) High power: the tumor cells are large with amphophilic cytoplasm and moderate nuclear hyperchromasia and pleomorphism. Some nuclei show prominent nucleoli. Mitoses are identified. 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{"pdf_hash": "b62b498f54ee67458344563f5f5f5067afb85d45", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 Approximately 1 month after presentation, representative images of a brain MRI with gadolinium: T2-weighted (a) and FLAIR (b) images. Both demonstrate confluent, symmetric, and bilateral high signal in the periventricular white matter, sparing the subcortical U-fibers", "width": 1044, "height": 616, "subcaptions": {"a": [18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "fc9955e4-7850-4337-8482-0e00e48a80c7", "label": "a", "points": [[23.9, 24.7], [23.9, 613.6], [533.6, 613.6], [533.6, 24.7]], "color": "yellow"}, {"id": "3d974f42-0af7-4049-a27b-63ba500d9844", "label": "b", "points": [[543.5, 26.4], [543.5, 611.9], [1041.6, 611.9], [1041.6, 26.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Approximately", "start": 7, "end": 20, "id": 3}, {"text": "1", "start": 21, "end": 22, "id": 4}, {"text": "month", "start": 23, "end": 28, "id": 5}, {"text": "after", "start": 29, "end": 34, "id": 6}, {"text": "presentation", "start": 35, "end": 47, "id": 7}, {"text": ",", "start": 47, "end": 48, "id": 8}, {"text": "representative", "start": 49, "end": 63, "id": 9}, {"text": "images", "start": 64, "end": 70, "id": 10}, {"text": "of", "start": 71, "end": 73, "id": 11}, {"text": "a", "start": 74, "end": 75, "id": 12}, {"text": "brain", "start": 76, "end": 81, "id": 13}, {"text": "MRI", "start": 82, "end": 85, "id": 14}, {"text": "with", "start": 86, "end": 90, "id": 15}, {"text": "gadolinium", "start": 91, "end": 101, "id": 16}, {"text": ":", "start": 101, "end": 102, "id": 17}, {"text": "T2-weighted", "start": 103, "end": 114, "id": 18}, {"text": "(", "start": 115, "end": 116, "id": 19}, {"text": "a", "start": 116, "end": 117, "id": 20}, {"text": ")", "start": 117, "end": 118, "id": 21}, {"text": "and", "start": 119, "end": 122, "id": 22}, {"text": "FLAIR", "start": 123, "end": 128, "id": 23}, {"text": "(", "start": 129, "end": 130, "id": 24}, {"text": "b", "start": 130, "end": 131, "id": 25}, {"text": ")", "start": 131, "end": 132, "id": 26}, {"text": "images", "start": 133, "end": 139, "id": 27}, {"text": ".", "start": 139, "end": 140, "id": 28}, {"text": "Both", "start": 141, "end": 145, "id": 29}, {"text": "demonstrate", "start": 146, "end": 157, "id": 30}, {"text": "confluent", "start": 158, "end": 167, "id": 31}, {"text": ",", "start": 167, "end": 168, "id": 32}, {"text": "symmetric", "start": 169, "end": 178, "id": 33}, {"text": ",", "start": 178, "end": 179, "id": 34}, {"text": "and", "start": 180, "end": 183, "id": 35}, {"text": "bilateral", "start": 184, "end": 193, "id": 36}, {"text": "high", "start": 194, "end": 198, "id": 37}, {"text": "signal", "start": 199, "end": 205, "id": 38}, {"text": "in", "start": 206, "end": 208, "id": 39}, {"text": "the", "start": 209, "end": 212, "id": 40}, {"text": "periventricular", "start": 213, "end": 228, "id": 41}, {"text": "white", "start": 229, "end": 234, "id": 42}, {"text": "matter", "start": 235, "end": 241, "id": 43}, {"text": ",", "start": 241, "end": 242, "id": 44}, {"text": "sparing", "start": 243, "end": 250, "id": 45}, {"text": "the", "start": 251, "end": 254, "id": 46}, {"text": "subcortical", "start": 255, "end": 266, "id": 47}, {"text": "U", "start": 267, "end": 268, "id": 48}, {"text": "-", "start": 268, "end": 269, "id": 49}, {"text": "fibers", "start": 269, "end": 275, "id": 50}]}
{"pdf_hash": "05de190f4196a96effc6767eb09bbd1cb1a7f96a", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "FIGURE 1 | (A) Transcranial magnetic stimulation (TMS)-induced motor evoked potentials (MEP) heat map over M1. Brighter colors represent larger MEP amplitudes. Orange circle denotes \u201chotspot.\u201d (B) Tissues identified from MRI and atlas CT, including brain (brown), skull (blue), eyes (green), air (purple), and scalp. Not shown are white matter and CSF. 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{"pdf_hash": "63fefd23e9a02f9f25c0713e13a303feaf8bfb6b", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 Case 2. Multimodal imaging of the left eye. CFP (a), FA (c), and ICGA (d) show a large occult CNV (asterisk) with no evidence of reticular pseudodrusen on blue FAF (b). OCT scan in correspondence of the fovea shows subretinal fluid (SRF), a shallow PED, and a foveomacular retinoschisis with characteristic splitting of the OPL (arrows) at presentation (e); 3 months (g) and 12 months (i) after the initiation of anti-VEGF injections, SRF is no more detectable and retinoschisis is still evident. 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{"pdf_hash": "aede38dea8c7442b6b4f42e8d87d1d03a4312607", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. Transverse CT (A\u2013C) and MRI (D\u2013F) in Dog 2. The urinary bladder mass is irregular and isoattenuating to the muscular layer in noncontrast CT (A). The mass is attached to the ventral bladder wall (B and C) and enhanced more intensely than the remainder of the bladder wall on arterial phase (B, arrows). On T2W image, the low signal intensity of the muscular layer is interrupted by the tumor (D, arrow). 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{"pdf_hash": "a6a01c6a5cf1ae41f444038cc2f6dce21b5f17ef", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Diagnostic Imaging. (a) Chest computed tomographic showing multiple metastatic nodules. (b) Technetium-99 methylene diphosphonate bone scintigraphy showing abnormally strong uptakes at the distal site of the right femur, proximal site of the right tibia, and right ankle.", "width": 660, "height": 586, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15], "b": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "1a71d7f3-4c18-42d1-b542-9389a93c9b50", "label": "a", "points": [[9.2, 48.8], [9.2, 386.6], [422, 386.6], [422, 48.8]], "color": "yellow"}, {"id": "a0d3abc3-2d38-453b-86ad-edc381dda8ae", "label": "b", "points": [[458.5, 8.2], [458.5, 582.6], [659.7, 582.6], [659.7, 8.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Diagnostic", "start": 9, "end": 19, "id": 2}, {"text": "Imaging", "start": 20, "end": 27, "id": 3}, {"text": ".", "start": 27, "end": 28, "id": 4}, {"text": "(", "start": 29, "end": 30, "id": 5}, {"text": "a", "start": 30, "end": 31, "id": 6}, {"text": ")", "start": 31, "end": 32, "id": 7}, {"text": "Chest", "start": 33, "end": 38, "id": 8}, {"text": "computed", "start": 39, "end": 47, "id": 9}, {"text": "tomographic", "start": 48, "end": 59, "id": 10}, {"text": "showing", "start": 60, "end": 67, "id": 11}, {"text": "multiple", "start": 68, "end": 76, "id": 12}, {"text": "metastatic", "start": 77, "end": 87, "id": 13}, {"text": "nodules", "start": 88, "end": 95, "id": 14}, {"text": ".", "start": 95, "end": 96, "id": 15}, {"text": "(", "start": 97, "end": 98, "id": 16}, {"text": "b", "start": 98, "end": 99, "id": 17}, {"text": ")", "start": 99, "end": 100, "id": 18}, {"text": "Technetium-99", "start": 101, "end": 114, "id": 19}, {"text": "methylene", "start": 115, "end": 124, "id": 20}, {"text": "diphosphonate", "start": 125, "end": 138, "id": 21}, {"text": "bone", "start": 139, "end": 143, "id": 22}, {"text": "scintigraphy", "start": 144, "end": 156, "id": 23}, {"text": "showing", "start": 157, "end": 164, "id": 24}, {"text": "abnormally", "start": 165, "end": 175, "id": 25}, {"text": "strong", "start": 176, "end": 182, "id": 26}, {"text": "uptakes", "start": 183, "end": 190, "id": 27}, {"text": "at", "start": 191, "end": 193, "id": 28}, {"text": "the", "start": 194, "end": 197, "id": 29}, {"text": "distal", "start": 198, "end": 204, "id": 30}, {"text": "site", "start": 205, "end": 209, "id": 31}, {"text": "of", "start": 210, "end": 212, "id": 32}, {"text": "the", "start": 213, "end": 216, "id": 33}, {"text": "right", "start": 217, "end": 222, "id": 34}, {"text": "femur", "start": 223, "end": 228, "id": 35}, {"text": ",", "start": 228, "end": 229, "id": 36}, {"text": "proximal", "start": 230, "end": 238, "id": 37}, {"text": "site", "start": 239, "end": 243, "id": 38}, {"text": "of", "start": 244, "end": 246, "id": 39}, {"text": "the", "start": 247, "end": 250, "id": 40}, {"text": "right", "start": 251, "end": 256, "id": 41}, {"text": "tibia", "start": 257, "end": 262, "id": 42}, {"text": ",", "start": 262, "end": 263, "id": 43}, {"text": "and", "start": 264, "end": 267, "id": 44}, {"text": "right", "start": 268, "end": 273, "id": 45}, {"text": "ankle", "start": 274, "end": 279, "id": 46}, {"text": ".", "start": 279, "end": 280, "id": 47}]}
{"pdf_hash": "e2b418e2af56a151e9bc9484d7a6c856ca76ae16", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Axial CT (first column), PET (second column) and PET/CT (third column) showed multiple areas of symmetrically increased FDG uptake corresponding to several muscle groups (yellow arrows), without any significant abnormalities at the corresponding CT scan. The muscles with increased FDG uptake bilaterally were the infraspinatus (first row; SUVmax: 6.8 on the left and 5.6 on the right), the", "width": 1184, "height": 1296, "subcaptions": {"a": [3, 4, 5, 6, 7, 8], "b": [10, 11, 12, 13, 14], "c": [16, 17, 18, 19, 20, 21, 22]}, "subfigures": [{"id": "dc5d91ee-2302-4505-b937-d11e2ddd6c4c", "label": "a", "points": [[2.9, 3.4], [2.9, 1286.5], [403.1, 1286.5], [403.1, 3.4]], "color": "yellow"}, {"id": "9c48a0b8-ae51-4e91-a98c-2e4fec9d37b8", "label": "b", "points": [[405, 5.3], [405, 1290.2], [767.8, 1290.2], [767.8, 5.3]], "color": "cyan"}, {"id": "bfce40d0-dd6b-48ad-85f7-c70fe0e12684", "label": "c", "points": [[773.5, 5.3], [773.5, 1282.7], [1171.8, 1282.7], [1171.8, 5.3]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Axial", "start": 7, "end": 12, "id": 3}, {"text": "CT", "start": 13, "end": 15, "id": 4}, {"text": "(", "start": 16, "end": 17, "id": 5}, {"text": "first", "start": 17, "end": 22, "id": 6}, {"text": "column", "start": 23, "end": 29, "id": 7}, {"text": ")", "start": 29, "end": 30, "id": 8}, {"text": ",", "start": 30, "end": 31, "id": 9}, {"text": "PET", "start": 32, "end": 35, "id": 10}, {"text": "(", "start": 36, "end": 37, "id": 11}, {"text": "second", "start": 37, "end": 43, "id": 12}, {"text": "column", "start": 44, "end": 50, "id": 13}, {"text": ")", "start": 50, "end": 51, "id": 14}, {"text": "and", "start": 52, "end": 55, "id": 15}, {"text": "PET", "start": 56, "end": 59, "id": 16}, {"text": "/", "start": 59, "end": 60, "id": 17}, {"text": "CT", "start": 60, "end": 62, "id": 18}, {"text": "(", "start": 63, "end": 64, "id": 19}, {"text": "third", "start": 64, "end": 69, "id": 20}, {"text": "column", "start": 70, "end": 76, "id": 21}, {"text": ")", "start": 76, "end": 77, "id": 22}, {"text": "showed", "start": 78, "end": 84, "id": 23}, {"text": "multiple", "start": 85, "end": 93, "id": 24}, {"text": "areas", "start": 94, "end": 99, "id": 25}, {"text": "of", "start": 100, "end": 102, "id": 26}, {"text": "symmetrically", "start": 103, "end": 116, "id": 27}, {"text": "increased", "start": 117, "end": 126, "id": 28}, {"text": "FDG", "start": 127, "end": 130, "id": 29}, {"text": "uptake", "start": 131, "end": 137, "id": 30}, {"text": "corresponding", "start": 138, "end": 151, "id": 31}, {"text": "to", "start": 152, "end": 154, "id": 32}, {"text": "several", "start": 155, "end": 162, "id": 33}, {"text": "muscle", "start": 163, "end": 169, "id": 34}, {"text": "groups", "start": 170, "end": 176, "id": 35}, {"text": "(", "start": 177, "end": 178, "id": 36}, {"text": "yellow", "start": 178, "end": 184, "id": 37}, {"text": "arrows", "start": 185, "end": 191, "id": 38}, {"text": ")", "start": 191, "end": 192, "id": 39}, {"text": ",", "start": 192, "end": 193, "id": 40}, {"text": "without", "start": 194, "end": 201, "id": 41}, {"text": "any", "start": 202, "end": 205, "id": 42}, {"text": "significant", "start": 206, "end": 217, "id": 43}, {"text": "abnormalities", "start": 218, "end": 231, "id": 44}, {"text": "at", "start": 232, "end": 234, "id": 45}, {"text": "the", "start": 235, "end": 238, "id": 46}, {"text": "corresponding", "start": 239, "end": 252, "id": 47}, {"text": "CT", "start": 253, "end": 255, "id": 48}, {"text": "scan", "start": 256, "end": 260, "id": 49}, {"text": ".", "start": 260, "end": 261, "id": 50}, {"text": "The", "start": 262, "end": 265, "id": 51}, {"text": "muscles", "start": 266, "end": 273, "id": 52}, {"text": "with", "start": 274, "end": 278, "id": 53}, {"text": "increased", "start": 279, "end": 288, "id": 54}, {"text": "FDG", "start": 289, "end": 292, "id": 55}, {"text": "uptake", "start": 293, "end": 299, "id": 56}, {"text": "bilaterally", "start": 300, "end": 311, "id": 57}, {"text": "were", "start": 312, "end": 316, "id": 58}, {"text": "the", "start": 317, "end": 320, "id": 59}, {"text": "infraspinatus", "start": 321, "end": 334, "id": 60}, {"text": "(", "start": 335, "end": 336, "id": 61}, {"text": "first", "start": 336, "end": 341, "id": 62}, {"text": "row", "start": 342, "end": 345, "id": 63}, {"text": ";", "start": 345, "end": 346, "id": 64}, {"text": "SUVmax", "start": 347, "end": 353, "id": 65}, {"text": ":", "start": 353, "end": 354, "id": 66}, {"text": "6.8", "start": 355, "end": 358, "id": 67}, {"text": "on", "start": 359, "end": 361, "id": 68}, {"text": "the", "start": 362, "end": 365, "id": 69}, {"text": "left", "start": 366, "end": 370, "id": 70}, {"text": "and", "start": 371, "end": 374, "id": 71}, {"text": "5.6", "start": 375, "end": 378, "id": 72}, {"text": "on", "start": 379, "end": 381, "id": 73}, {"text": "the", "start": 382, "end": 385, "id": 74}, {"text": "right", "start": 386, "end": 391, "id": 75}, {"text": ")", "start": 391, "end": 392, "id": 76}, {"text": ",", "start": 392, "end": 393, "id": 77}, {"text": "the", "start": 394, "end": 397, "id": 78}]}
{"pdf_hash": "334c1530a95063cde1467965b2a19b8b6d0dd632", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Brain MRI findings of two patients with mutations in TUBA1A. (a) Foetal MRI at 28 weeks of gestation of patient 1 (T2-weighted image). White arrowheads indicate the basal ganglia. (b-d) MRI findings at 6 days after the birth of patient 1 (b: T1-weighted image; c,d: Fluid Attenuated Inversion recovery [FLAIR]). The patient showed an extremely thin cerebral parenchyma, hypoplastic brain stem, and agenesis of the cerebellum and corpus callosum. Most of the intracranial space was occupied with cerebrospinal fluid. (e-h) MRI findings at 1 year of age of patient 2 (T1-weighted images). The patient showed marked ventricular dilatation with a thin cortex, agyria, or limited pachygyria, poorly differentiated dysmorphic basal ganglia, agenesis of the corpus callosum, and slightly hypoplastic cerebellar vermis. 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{"pdf_hash": "d2e8ea2cbf45ddf4409866c871e20fe930937309", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Images of hyaluronic acid (HA) for Patient 7. A) Point of injection on CT; B) 1 month after the injection on MRI; C) 2 months after the injection on MRI; D) 3 months after the injection on MRI", "width": 1300, "height": 934, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "c": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "d": [43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "e40e1007-80d2-45fe-90b1-cb7a754edb9a", "label": "a", "points": [[5.2, 2.7], [5.2, 446.3], [623.4, 446.3], [623.4, 2.7]], "color": "yellow"}, {"id": "73d93936-2462-47e3-a7da-c284dcbf2935", "label": "b", "points": [[676.8, 4.8], [676.8, 440.2], [1296.9, 440.2], [1296.9, 4.8]], "color": "cyan"}, {"id": "a89173ac-84f9-4653-bca2-8c89cebf498d", "label": "c", "points": [[9.3, 487.4], [9.3, 906.3], [627.5, 906.3], [627.5, 487.4]], "color": "magenta"}, {"id": "1131ffdb-d53a-4a53-b6ef-68322f79c450", "label": "d", "points": [[674.7, 481.2], [674.7, 906.3], [1292.8, 906.3], [1292.8, 481.2]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Images", "start": 8, "end": 14, "id": 4}, {"text": "of", "start": 15, "end": 17, "id": 5}, {"text": "hyaluronic", "start": 18, "end": 28, "id": 6}, {"text": "acid", "start": 29, "end": 33, "id": 7}, {"text": "(", "start": 34, "end": 35, "id": 8}, {"text": "HA", "start": 35, "end": 37, "id": 9}, {"text": ")", "start": 37, "end": 38, "id": 10}, {"text": "for", "start": 39, "end": 42, "id": 11}, {"text": "Patient", "start": 43, "end": 50, "id": 12}, {"text": "7", "start": 51, "end": 52, "id": 13}, {"text": ".", "start": 52, "end": 53, "id": 14}, {"text": "A", "start": 54, "end": 55, "id": 15}, {"text": ")", "start": 55, "end": 56, "id": 16}, {"text": "Point", "start": 57, "end": 62, "id": 17}, {"text": "of", "start": 63, "end": 65, "id": 18}, {"text": "injection", "start": 66, "end": 75, "id": 19}, {"text": "on", "start": 76, "end": 78, "id": 20}, {"text": "CT", "start": 79, "end": 81, "id": 21}, {"text": ";", "start": 81, "end": 82, "id": 22}, {"text": "B", "start": 83, "end": 84, "id": 23}, {"text": ")", "start": 84, "end": 85, "id": 24}, {"text": "1", "start": 86, "end": 87, "id": 25}, {"text": "month", "start": 88, "end": 93, "id": 26}, {"text": "after", "start": 94, "end": 99, "id": 27}, {"text": "the", "start": 100, "end": 103, "id": 28}, {"text": "injection", "start": 104, "end": 113, "id": 29}, {"text": "on", "start": 114, "end": 116, "id": 30}, {"text": "MRI", "start": 117, "end": 120, "id": 31}, {"text": ";", "start": 120, "end": 121, "id": 32}, {"text": "C", "start": 122, "end": 123, "id": 33}, {"text": ")", "start": 123, "end": 124, "id": 34}, {"text": "2", "start": 125, "end": 126, "id": 35}, {"text": "months", "start": 127, "end": 133, "id": 36}, {"text": "after", "start": 134, "end": 139, "id": 37}, {"text": "the", "start": 140, "end": 143, "id": 38}, {"text": "injection", "start": 144, "end": 153, "id": 39}, {"text": "on", "start": 154, "end": 156, "id": 40}, {"text": "MRI", "start": 157, "end": 160, "id": 41}, {"text": ";", "start": 160, "end": 161, "id": 42}, {"text": "D", "start": 162, "end": 163, "id": 43}, {"text": ")", "start": 163, "end": 164, "id": 44}, {"text": "3", "start": 165, "end": 166, "id": 45}, {"text": "months", "start": 167, "end": 173, "id": 46}, {"text": "after", "start": 174, "end": 179, "id": 47}, {"text": "the", "start": 180, "end": 183, "id": 48}, {"text": "injection", "start": 184, "end": 193, "id": 49}, {"text": "on", "start": 194, "end": 196, "id": 50}, {"text": "MRI", "start": 197, "end": 200, "id": 51}]}
{"pdf_hash": "55a86577e528ab7c4e0714a48541a89dd6608b6f", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4. Modeling dTTP and ANS-dTTP in the HIV-RT complex. The backbone structures of p66 and p51 are rendered in brown and green ribbons, respectively. The lighter brown region represents residues from 1 to 235 (finger and palm domains) which were allowed to move during the simulations. The DNA template and primer backbone structures are rendered in red and blue ribbons, and two Mg 2+ ions are rendered as cyan spheres. In each figure, the following colors were used for the different atoms: C-green, O-red, N-blue, Ppink, and S-yellow. (A) The X-ray structure of the dTTP was displayed with the neighboring residues of the two Mg 2+ ions and the gamma-phosphate moiety: K65, K70, D110, V111, D113, D185 and D186. The dTTP structure is adjacent to the primer DNA in ball and stick. (B) For the initial structure of ANS-dTTP, the ANS group was manually attached to an oxygen atom of the gammaphosphate group. The ten membered ring and sulfate group were placed without atomic overlaps against the existing atoms of the p66 domain of the HIV-RT structure. Forcefield parameters were developed for the ANS linked to the gamma-phosphate via an oxygen atom, instead of an NH group, to simplify the force field parameterization process. (C) Solvent accessible surface renderings for panel A is shown. (D) Solvent accessible surface renderings for panel B is shown. Viewing angles in panels C and D were slightly changed from those of A and B to more clearly show the locations of gamma-phosphate and ANS groups.", "width": 690, "height": 736, "subcaptions": {"a": [118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176], "b": [177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262], "c": [263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 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{"pdf_hash": "b06601a5c146023dc8badbf987175943dbc8b7f3", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Case 2. A US of the liver shows a 15-mm hypoechoic nodular lesion resembling a secondary solitary mass in the subcapsular portion of segment VI. B Four months later, US shows a 15-mm targetlike lesion in the subcapsular portion of segment VI, with a central hyperechoic core surrounded by a peripheral hypoechoic ring. C Helical CT in the portal phase after intravenous administration of iodinated contrast material shows a nonenhancing hypodense nodular lesion in segment VI. D On a GRASE SPIR T2W image, the lesion appears as a small, strongly hypointense mass. E DW image (b 500) shows a hypointense nodule. F Biopsy specimen of the solitary necrotic nodule of the liver. Hematoxylin and eosin; original magnification, 40 . 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{"pdf_hash": "2fd59f4bf73b41fd387542db7bccd1fc6e1695be", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 Bedside CXR and simulated DTS reconstruction of a 49-year-old man who was admitted to the ICU after a neurosurgical intervention with removal of a fourth ventricle ependymoma. Five days after surgery he developed respiratory insufficiency. a Bedside CXR shows subcutaneous emphysema in the neck and pulmonary consolidations bilaterally in the basal parts of both lungs. b Simulated DTS acquisition from a CT examination, performed 1 h later. Because of the discrepancy between respiratory function and findings on CXR, the CT examination was performed to rule out pulmonary embolism. c Slice of the DTS reconstruction of the simulated acquisitions at the level of the heart shows linear areas of hyperlucency around the heart and in the paravertebral region (black arrows). Also note an area of relative hyperlucency in the left lung with a clear delineation of the adjacent consolidation (white arrows). These findings are consistent with pneumomediastinum. d Slice of the DTS reconstruction of the simulated acquisitions more posterior than DTS reconstruction A shown in c, showing a large retrocardiac consolidation with air bronchogram (black arrows). e A coronal reformatted CT image confirms the pneumomediastinum and a large consolidation (f) with air bronchogram, consistent with subtotal atelectasis of the left lower lobe. Due to the retrocardiac location, the consolidation is not visible on the CXR. Moreover, the extent of the pneumomediastinum is better appreciated on the DTS reconstructions compared to the bedside radiograph", "width": 1342, "height": 936, "subcaptions": {"a": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "b": [63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99], "c": [100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164], "d": [165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197], "e": [198, 199, 200, 201, 202, 203, 204, 205, 206], "f": [207, 208, 209, 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{"pdf_hash": "b8a6a7a8df4db054f5149ff85529e9c2b31dbd16", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3 \u2013 Axial brain CT scan at the level of cerebellum, in subdural window performed 1 week after initial craniotomy. (A) Showing bilateral cerebellar hemorrhages (white arrow) which closely resemble the zebra sign in addition to elements of interstitial hemorrhage (mixed pattern). (B) The white arrow points toward a slight downward extension of the right cerebellar hemorrhage compared to the left side.", "width": 1200, "height": 738, "subcaptions": {"a": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75]}, "subfigures": [{"id": "cef6079e-55c6-4244-9c7a-f810f550a45d", "label": "a", "points": [[0, 0], [0, 737.5], [595.3, 737.5], [595.3, 0]], "color": "yellow"}, {"id": "72ac9f7f-50a1-4c00-8e4d-305ce4f76113", "label": "b", "points": [[612.3, 737.5], [612.3, 5.7], [1198.1, 5.7], [1198.1, 737.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "\u2013", "start": 7, "end": 8, "id": 3}, {"text": "Axial", "start": 9, "end": 14, "id": 4}, {"text": "brain", "start": 15, "end": 20, "id": 5}, {"text": "CT", "start": 21, "end": 23, "id": 6}, {"text": "scan", "start": 24, "end": 28, "id": 7}, {"text": "at", "start": 29, "end": 31, "id": 8}, {"text": "the", "start": 32, "end": 35, "id": 9}, {"text": "level", "start": 36, "end": 41, "id": 10}, {"text": "of", "start": 42, "end": 44, "id": 11}, {"text": "cerebellum", "start": 45, "end": 55, "id": 12}, {"text": ",", "start": 55, "end": 56, "id": 13}, {"text": "in", "start": 57, "end": 59, "id": 14}, {"text": "subdural", "start": 60, "end": 68, "id": 15}, {"text": "window", "start": 69, "end": 75, "id": 16}, {"text": "performed", "start": 76, "end": 85, "id": 17}, {"text": "1", "start": 86, "end": 87, "id": 18}, {"text": "week", "start": 88, "end": 92, "id": 19}, {"text": "after", "start": 93, "end": 98, "id": 20}, {"text": "initial", "start": 99, "end": 106, "id": 21}, {"text": "craniotomy", "start": 107, "end": 117, "id": 22}, {"text": ".", "start": 117, "end": 118, "id": 23}, {"text": "(", "start": 119, "end": 120, "id": 24}, {"text": "A", "start": 120, "end": 121, "id": 25}, {"text": ")", "start": 121, "end": 122, "id": 26}, {"text": "Showing", "start": 123, "end": 130, "id": 27}, {"text": "bilateral", "start": 131, "end": 140, "id": 28}, {"text": "cerebellar", "start": 141, "end": 151, "id": 29}, {"text": "hemorrhages", "start": 152, "end": 163, "id": 30}, {"text": "(", "start": 164, "end": 165, "id": 31}, {"text": "white", "start": 165, "end": 170, "id": 32}, {"text": "arrow", "start": 171, "end": 176, "id": 33}, {"text": ")", "start": 176, "end": 177, "id": 34}, {"text": "which", "start": 178, "end": 183, "id": 35}, {"text": "closely", "start": 184, "end": 191, "id": 36}, {"text": "resemble", "start": 192, "end": 200, "id": 37}, {"text": "the", "start": 201, "end": 204, "id": 38}, {"text": "zebra", "start": 205, "end": 210, "id": 39}, {"text": "sign", "start": 211, "end": 215, "id": 40}, {"text": "in", "start": 216, "end": 218, "id": 41}, {"text": "addition", "start": 219, "end": 227, "id": 42}, {"text": "to", "start": 228, "end": 230, "id": 43}, {"text": "elements", "start": 231, "end": 239, "id": 44}, {"text": "of", "start": 240, "end": 242, "id": 45}, {"text": "interstitial", "start": 243, "end": 255, "id": 46}, {"text": "hemorrhage", "start": 256, "end": 266, "id": 47}, {"text": "(", "start": 267, "end": 268, "id": 48}, {"text": "mixed", "start": 268, "end": 273, "id": 49}, {"text": "pattern", "start": 274, "end": 281, "id": 50}, {"text": ")", "start": 281, "end": 282, "id": 51}, {"text": ".", "start": 282, "end": 283, "id": 52}, {"text": "(", "start": 284, "end": 285, "id": 53}, {"text": "B", "start": 285, "end": 286, "id": 54}, {"text": ")", "start": 286, "end": 287, "id": 55}, {"text": "The", "start": 288, "end": 291, "id": 56}, {"text": "white", "start": 292, "end": 297, "id": 57}, {"text": "arrow", "start": 298, "end": 303, "id": 58}, {"text": "points", "start": 304, "end": 310, "id": 59}, {"text": "toward", "start": 311, "end": 317, "id": 60}, {"text": "a", "start": 318, "end": 319, "id": 61}, {"text": "slight", "start": 320, "end": 326, "id": 62}, {"text": "downward", "start": 327, "end": 335, "id": 63}, {"text": "extension", "start": 336, "end": 345, "id": 64}, {"text": "of", "start": 346, "end": 348, "id": 65}, {"text": "the", "start": 349, "end": 352, "id": 66}, {"text": "right", "start": 353, "end": 358, "id": 67}, {"text": "cerebellar", "start": 359, "end": 369, "id": 68}, {"text": "hemorrhage", "start": 370, "end": 380, "id": 69}, {"text": "compared", "start": 381, "end": 389, "id": 70}, {"text": "to", "start": 390, "end": 392, "id": 71}, {"text": "the", "start": 393, "end": 396, "id": 72}, {"text": "left", "start": 397, "end": 401, "id": 73}, {"text": "side", "start": 402, "end": 406, "id": 74}, {"text": ".", "start": 406, "end": 407, "id": 75}]}
{"pdf_hash": "63bd0d837abc23f4bf4a89e8d33658ef79617a77", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig 4. Altered centrality of the sensory-motor network in the remitting phase of RRMS patients. The spatial distribution of abnormal DC (a) and EC (b) in the remitting phase of RRMS patients (P < 0.05, AlphaSim corrected critical cluster size k = 20) as visualized using surface brain imaging in Brainnet Viewer (www.nitrc.org/projects/bnv/). doi:10.1371/journal.pone.0130524.g004", "width": 956, "height": 362, "subcaptions": {"a": [24, 25, 26, 27], "b": [32, 29, 30, 31]}, "subfigures": [{"id": "7089f117-28f6-4aca-95dd-7ef192e609bd", "label": "a", "points": [[6.9, 20.9], [6.9, 329], [449.4, 329], [449.4, 20.9]], "color": "yellow"}, {"id": "743d24fe-8645-47e6-a2c1-3bfe43d9a9b1", "label": "b", "points": [[472, 20.9], [472, 327.5], [925.1, 327.5], [925.1, 20.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "4", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Altered", "start": 7, "end": 14, "id": 3}, {"text": "centrality", "start": 15, "end": 25, "id": 4}, {"text": "of", "start": 26, "end": 28, "id": 5}, {"text": "the", "start": 29, "end": 32, "id": 6}, {"text": "sensory", "start": 33, "end": 40, "id": 7}, {"text": "-", "start": 40, "end": 41, "id": 8}, {"text": "motor", "start": 41, "end": 46, "id": 9}, {"text": "network", "start": 47, "end": 54, "id": 10}, {"text": "in", "start": 55, "end": 57, "id": 11}, {"text": "the", "start": 58, "end": 61, "id": 12}, {"text": "remitting", "start": 62, "end": 71, "id": 13}, {"text": "phase", "start": 72, "end": 77, "id": 14}, {"text": "of", "start": 78, "end": 80, "id": 15}, {"text": "RRMS", "start": 81, "end": 85, "id": 16}, {"text": "patients", "start": 86, "end": 94, "id": 17}, {"text": ".", "start": 94, "end": 95, "id": 18}, {"text": "The", "start": 96, "end": 99, "id": 19}, {"text": "spatial", "start": 100, "end": 107, "id": 20}, {"text": "distribution", "start": 108, "end": 120, "id": 21}, {"text": "of", "start": 121, "end": 123, "id": 22}, {"text": "abnormal", "start": 124, "end": 132, "id": 23}, {"text": "DC", "start": 133, "end": 135, "id": 24}, {"text": "(", "start": 136, "end": 137, "id": 25}, {"text": "a", "start": 137, "end": 138, "id": 26}, {"text": ")", "start": 138, "end": 139, "id": 27}, {"text": "and", "start": 140, "end": 143, "id": 28}, {"text": "EC", "start": 144, "end": 146, "id": 29}, {"text": "(", "start": 147, "end": 148, "id": 30}, {"text": "b", "start": 148, "end": 149, "id": 31}, {"text": ")", "start": 149, "end": 150, "id": 32}, {"text": "in", "start": 151, "end": 153, "id": 33}, {"text": "the", "start": 154, "end": 157, "id": 34}, {"text": "remitting", "start": 158, "end": 167, "id": 35}, {"text": "phase", "start": 168, "end": 173, "id": 36}, {"text": "of", "start": 174, "end": 176, "id": 37}, {"text": "RRMS", "start": 177, "end": 181, "id": 38}, {"text": "patients", "start": 182, "end": 190, "id": 39}, {"text": "(", "start": 191, "end": 192, "id": 40}, {"text": "P", "start": 192, "end": 193, "id": 41}, {"text": "<", "start": 194, "end": 195, "id": 42}, {"text": "0.05", "start": 196, "end": 200, "id": 43}, {"text": ",", "start": 200, "end": 201, "id": 44}, {"text": "AlphaSim", "start": 202, "end": 210, "id": 45}, {"text": "corrected", "start": 211, "end": 220, "id": 46}, {"text": "critical", "start": 221, "end": 229, "id": 47}, {"text": "cluster", "start": 230, "end": 237, "id": 48}, {"text": "size", "start": 238, "end": 242, "id": 49}, {"text": "k", "start": 243, "end": 244, "id": 50}, {"text": "=", "start": 245, "end": 246, "id": 51}, {"text": "20", "start": 247, "end": 249, "id": 52}, {"text": ")", "start": 249, "end": 250, "id": 53}, {"text": "as", "start": 251, "end": 253, "id": 54}, {"text": "visualized", "start": 254, "end": 264, "id": 55}, {"text": "using", "start": 265, "end": 270, "id": 56}, {"text": "surface", "start": 271, "end": 278, "id": 57}, {"text": "brain", "start": 279, "end": 284, "id": 58}, {"text": "imaging", "start": 285, "end": 292, "id": 59}, {"text": "in", "start": 293, "end": 295, "id": 60}, {"text": "Brainnet", "start": 296, "end": 304, "id": 61}, {"text": "Viewer", "start": 305, "end": 311, "id": 62}, {"text": "(", "start": 312, "end": 313, "id": 63}, {"text": "www.nitrc.org/projects/bnv/", "start": 313, "end": 340, "id": 64}, {"text": ")", "start": 340, "end": 341, "id": 65}, {"text": ".", "start": 341, "end": 342, "id": 66}, {"text": "doi:10.1371", "start": 343, "end": 354, "id": 67}, {"text": "/", "start": 354, "end": 355, "id": 68}, {"text": "journal.pone.0130524.g004", "start": 355, "end": 380, "id": 69}]}
{"pdf_hash": "aa4e9419ace89c5d38101d14aae657d32e5f5e7e", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5. Ultrastructural changes observed after 6 and 24 h of buparvaquone treatment. (A)\u2013(C) show cells processed after 6 h, and (D)\u2013(F) shows specimens processed after 24 h of drug treatment. (A) and (B) (B = higher magnification view of A) show an increased vacuolization (v) and accumulation of intravacuolar membrane stacks (apv). In other specimens such as in (C), vacuoles become rather spacious and occupied large parts of the schizont cytoplasm. (D)\u2013(F) show cells processed after 24 h of buparvaquone treatment, with considerable shrinkage of parasite nuclei (n) and electron dense deposits within the nuclear matrix and also at the schizont periphery adjacent to the host cell cytoplasm (E) and (F) (at a higher magnification of E). The button-like electron dense structures remained associated with the schizont periphery in some cells (D, marked with white triangles), in others cells (Fig. 5E and F), these structures were completely lost. Note that in all instances the parasite plasma membrane (white arrows) remained intact, and no alterations in the host cell were observed. mito = host cell mitochondria. 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{"pdf_hash": "514c02422e0eaf95e919a3ef4cbc93be9ef258c8", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3: 19-year-old male of grade IV splenic injury underwent combined transcatheter arterial embolization. (A, B) Contrast-enhanced axial and coronal CT at portal venous phase shows a pseudoaneurysm (arrow) at the lacerated spleen (S) surrounded by hemoperitoneum (H). (C) Angiography discloses multiple tiny pseudoaneurysms (arrow) and the supplying branch artery (arrowhead). 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{"pdf_hash": "2006e306295a79d1a0f3c4e0c67920d22af7d7f7", "fig_key": "Figure4", "fig_uri": "9-Figure4-1.png", "text": "Fig. 4. Process of fusion imaging between real-time US and reference MR images. A. Plane registration: after loading of reference MR images to US equipment that implemented fusion imaging technique; plane registration was done. In this case, sagittal plane was used for plane registration. B. Point registration: after plane registration, point registration was performed by selecting same anatomic landmark (proximal right portal vein in this case) on both real-time working US and reference MR images. C. Target tumor marking: after point registration, targeted tumor was marked on reference MR image. Location of targeted tumor on real-time working US was immediately visualized in corresponding location. 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{"pdf_hash": "1e3029afdbe7cba5d8603c496f3d1bbd7142f5f6", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. A 52-year-old woman with a mass detected on the screening breast ultrasound (US) in left breast, upper center. (A) An initial US image shows a 1.0 cm oval shape circumscribed isoechoic mass corresponding to Breast Imaging Reporting and Data System (BI-RADS) category 3 on US (arrows). (B) and (C) at the 12 months and 2 years follow-up US, the mass in the left upper center was not changed, and downgraded to BI-RADS category 2. 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{"pdf_hash": "9187fb12681afc14efd7e5bfda64603a5317da07", "fig_key": "Figure12", "fig_uri": "16-Figure12-1.png", "text": "Figure 12. A, CAM II kinase-or-immunoreactive cells and neuropil concentrated in a large island in the caudate nucleus. Arrows indicate two larger stained cells. Scale bar, 100 pm. B, CAM II kinase-wimmunoreactive staining of the claustrum (CT) and putamen (Pu). Arrows indicate two large stained cells. Scale bar, 100 pm. C, CAM II kinase-oc immunoreactivity in large cells of the basal nucleus of Meynert (BNA4) and in the adjacent putamen (Pu). Scale bar, 25 pm. D, CAM II kinase-cu immunoreactivity in cells and neuropil of the putamen (Pu) but apparently in fibers only in the external division of the globus pallidus (GPe). See Figure 13A. 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{"pdf_hash": "cca4b81594f8327617fab4415f457fd8bfaa9cd5", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Punctate white matter lesions with a cluster pattern. Early (A\u2013C) and term equivalent (D\u2013F) scans in an infant of 31+3 weeks gestation with lesions in a cluster pattern. T2-weighted imaging shows multiple lesions throughout the white matter (A) that are also clearly visible on inversion recovery imaging (B). The apparent diffusion coefficient -map shows restricted diffusion at the site of the lesions (C). The SWI sequence (not shown) did not show any signal loss. The arrow indicates one of the lesions, visible on all images. At term equivalent age, lesion load has diminished. Lesions are now better appreciated on T1-weighted imaging (E), compared with T2-weighted imaging (D). Again, SWI does not show signal loss (F). 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{"pdf_hash": "ccb5dee6251393fb65036c5d5c7ac1f30f9cbc15", "fig_key": "Figure7", "fig_uri": "14-Figure7-1.png", "text": "Fig. 7 CT analysis showing bone damage was still present in the 3D-PLA, 3D-PLA + human gingival mesenchymal stem cells (hGMSCs), and 3D-PLA + extracellular vesicles (EVs) groups. On the contrary, in the 3D-PLA + EVs + hGMSCs, 3D-PLA + polyethyleneimine (PEI)-EVs, and 3D-PLA + PEI-EVs + hGMSCs groups the complete repair of the calvarial defect was shown. 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{"pdf_hash": "00429a03ea569ab7a4bb2793869eae49a3f9bf6e", "fig_key": "Figure8", "fig_uri": "9-Figure8-1.png", "text": "Fig. 8 Ultrasound image obtained from a 54-year-old patient with a suspicious mass: \u0351a\u0352 contralateral normal site and \u0351b\u0352 lesion site.", "width": 1108, "height": 434, "subcaptions": {"a": [17, 18, 19, 20], "b": [22, 23, 24, 25]}, "subfigures": [{"id": "22fd60cf-6a30-48d4-a8ea-5100fa02f3e3", "label": "a", "points": [[30, 2.9], [30, 358.3], [525.4, 358.3], [525.4, 2.9]], "color": "yellow"}, {"id": "54b779c3-e01d-4706-a3aa-19c6909c74bb", "label": "b", "points": [[581.4, 1.2], [581.4, 353], [1094.3, 353], [1094.3, 1.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "8", "start": 5, "end": 6, "id": 2}, {"text": "Ultrasound", "start": 7, "end": 17, "id": 3}, {"text": "image", "start": 18, "end": 23, "id": 4}, {"text": "obtained", "start": 24, "end": 32, "id": 5}, {"text": "from", "start": 33, "end": 37, "id": 6}, {"text": "a", "start": 38, "end": 39, "id": 7}, {"text": "54-year", "start": 40, "end": 47, "id": 8}, {"text": "-", "start": 47, "end": 48, "id": 9}, {"text": "old", "start": 48, "end": 51, "id": 10}, {"text": "patient", "start": 52, "end": 59, "id": 11}, {"text": "with", "start": 60, "end": 64, "id": 12}, {"text": "a", "start": 65, "end": 66, "id": 13}, {"text": "suspicious", "start": 67, "end": 77, "id": 14}, {"text": "mass", "start": 78, "end": 82, "id": 15}, {"text": ":", "start": 82, "end": 83, "id": 16}, {"text": "\u0351a\u0352", "start": 84, "end": 87, "id": 17}, {"text": "contralateral", "start": 88, "end": 101, "id": 18}, {"text": "normal", "start": 102, "end": 108, "id": 19}, {"text": "site", "start": 109, "end": 113, "id": 20}, {"text": "and", "start": 114, "end": 117, "id": 21}, {"text": "\u0351b\u0352", "start": 118, "end": 121, "id": 22}, {"text": "lesion", "start": 122, "end": 128, "id": 23}, {"text": "site", "start": 129, "end": 133, "id": 24}, {"text": ".", "start": 133, "end": 134, "id": 25}]}
{"pdf_hash": "cb54235cadd150a1db0ccd58b3a261da9ac22223", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: (a-c) A computerized tomography scan of right shoulder joint shows a large pedunculated bony lesion originating from the medial aspect of the superior margin of right scapula. The mass measures 5.3\u00d73.0\u00d71.5 cm in size. The tumor shows speculated sclerosed margins with no cortical break.", "width": 682, "height": 318, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53]}, "subfigures": [{"id": "06b43b4b-4ae2-4f54-8224-5c4925246843", "label": "a", "points": [[15.7, 13.8], [15.7, 283.2], [235.4, 283.2], [235.4, 13.8]], "color": "yellow"}, {"id": "bdfd22a7-5125-4f34-b579-81845ab29159", "label": "b", "points": [[240.8, 16], [240.8, 284.2], [454.1, 284.2], [454.1, 16]], "color": "cyan"}, {"id": "e6294ba9-00f6-4d13-bfd2-896dba8f7c30", "label": "c", "points": [[463.8, 16], [463.8, 286.4], [669.6, 286.4], [669.6, 16]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": "-", "start": 12, "end": 13, "id": 5}, {"text": "c", "start": 13, "end": 14, "id": 6}, {"text": ")", "start": 14, "end": 15, "id": 7}, {"text": "A", "start": 16, "end": 17, "id": 8}, {"text": "computerized", "start": 18, "end": 30, "id": 9}, {"text": "tomography", "start": 31, "end": 41, "id": 10}, {"text": "scan", "start": 42, "end": 46, "id": 11}, {"text": "of", "start": 47, "end": 49, "id": 12}, {"text": "right", "start": 50, "end": 55, "id": 13}, {"text": "shoulder", "start": 56, "end": 64, "id": 14}, {"text": "joint", "start": 65, "end": 70, "id": 15}, {"text": "shows", "start": 71, "end": 76, "id": 16}, {"text": "a", "start": 77, "end": 78, "id": 17}, {"text": "large", "start": 79, "end": 84, "id": 18}, {"text": "pedunculated", "start": 85, "end": 97, "id": 19}, {"text": "bony", "start": 98, "end": 102, "id": 20}, {"text": "lesion", "start": 103, "end": 109, "id": 21}, {"text": "originating", "start": 110, "end": 121, "id": 22}, {"text": "from", "start": 122, "end": 126, "id": 23}, {"text": "the", "start": 127, "end": 130, "id": 24}, {"text": "medial", "start": 131, "end": 137, "id": 25}, {"text": "aspect", "start": 138, "end": 144, "id": 26}, {"text": "of", "start": 145, "end": 147, "id": 27}, {"text": "the", "start": 148, "end": 151, "id": 28}, {"text": "superior", "start": 152, "end": 160, "id": 29}, {"text": "margin", "start": 161, "end": 167, "id": 30}, {"text": "of", "start": 168, "end": 170, "id": 31}, {"text": "right", "start": 171, "end": 176, "id": 32}, {"text": "scapula", "start": 177, "end": 184, "id": 33}, {"text": ".", "start": 184, "end": 185, "id": 34}, {"text": "The", "start": 186, "end": 189, "id": 35}, {"text": "mass", "start": 190, "end": 194, "id": 36}, {"text": "measures", "start": 195, "end": 203, "id": 37}, {"text": "5.3\u00d73.0\u00d71.5", "start": 204, "end": 215, "id": 38}, {"text": "cm", "start": 216, "end": 218, "id": 39}, {"text": "in", "start": 219, "end": 221, "id": 40}, {"text": "size", "start": 222, "end": 226, "id": 41}, {"text": ".", "start": 226, "end": 227, "id": 42}, {"text": "The", "start": 228, "end": 231, "id": 43}, {"text": "tumor", "start": 232, "end": 237, "id": 44}, {"text": "shows", "start": 238, "end": 243, "id": 45}, {"text": "speculated", "start": 244, "end": 254, "id": 46}, {"text": "sclerosed", "start": 255, "end": 264, "id": 47}, {"text": "margins", "start": 265, "end": 272, "id": 48}, {"text": "with", "start": 273, "end": 277, "id": 49}, {"text": "no", "start": 278, "end": 280, "id": 50}, {"text": "cortical", "start": 281, "end": 289, "id": 51}, {"text": "break", "start": 290, "end": 295, "id": 52}, {"text": ".", "start": 295, "end": 296, "id": 53}]}
{"pdf_hash": "3c0c6dfca4090e3feedc2d60cbdc3099a6cb31f6", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. AFM images of DNA translocation. Typical images of translocation activity by R 1 -complex after incubation for (a) 10 s, (b) 30 s and (c) 60 s in the presence of ATP and 724 bp DNA fragments, containing a single recognition site at 175 bp. At the position of the protein, which shows up as a white globular feature, one small DNA loop is observed that increases in size with longer incubation times. Scan range, 250 nm; z range, 3 nm. (d) Distribution of the loop size after incubation for 10 s. Translocation distances were fitted with a Gaussian distribution, resulting in an average translocation distance of 2.8 \u00b7 10 2 bp. (e and f ) R 2 complexes on 2364 bp DNA after incubation with ATP for several minutes. As expected, double loops of DNA are formed. 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{"pdf_hash": "1ef3ff4e1012612c3a09f1ce5573e5b7cf619ae7", "fig_key": "Figure8", "fig_uri": "10-Figure8-1.png", "text": "Fig. 8 Schistosomiasis with superimposed squamocellular carcinoma in a 48 year-old Gambian man with pelvic pain and tenderness, dysuria and difficult urination. Unenhanced (a) and post-contrast (b) CT images showed marked asymmetric solid mural thickening (*), with poor enhancement along the anterior right lateral and superior bladder", "width": 1370, "height": 486, "subcaptions": {"a": [27, 28, 29, 30], "b": [32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "c59582d6-f951-414d-9a50-5bcbe4ef0b49", "label": "a", "points": [[2.2, 6.1], [2.2, 452], [441.6, 452], [441.6, 6.1]], "color": "yellow"}, {"id": "c997d8ff-1634-49ea-b2cc-5078667c33b6", "label": "b", "points": [[454.6, 10.5], [454.6, 456.3], [906.9, 456.3], [906.9, 10.5]], "color": "cyan"}, {"id": "81cc59aa-0087-4224-b489-0dc8eeb9d008", "label": "c", "points": [[926.4, 6.1], [926.4, 452], [1361.4, 452], [1361.4, 6.1]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "8", "start": 5, "end": 6, "id": 2}, {"text": "Schistosomiasis", "start": 7, "end": 22, "id": 3}, {"text": "with", "start": 23, "end": 27, "id": 4}, {"text": "superimposed", "start": 28, "end": 40, "id": 5}, {"text": "squamocellular", "start": 41, "end": 55, "id": 6}, {"text": "carcinoma", "start": 56, "end": 65, "id": 7}, {"text": "in", "start": 66, "end": 68, "id": 8}, {"text": "a", "start": 69, "end": 70, "id": 9}, {"text": "48", "start": 71, "end": 73, "id": 10}, {"text": "year", "start": 74, "end": 78, "id": 11}, {"text": "-", "start": 78, "end": 79, "id": 12}, {"text": "old", "start": 79, "end": 82, "id": 13}, {"text": "Gambian", "start": 83, "end": 90, "id": 14}, {"text": "man", "start": 91, "end": 94, "id": 15}, {"text": "with", "start": 95, "end": 99, "id": 16}, {"text": "pelvic", "start": 100, "end": 106, "id": 17}, {"text": "pain", "start": 107, "end": 111, "id": 18}, {"text": "and", "start": 112, "end": 115, "id": 19}, {"text": "tenderness", "start": 116, "end": 126, "id": 20}, {"text": ",", "start": 126, "end": 127, "id": 21}, {"text": "dysuria", "start": 128, "end": 135, "id": 22}, {"text": "and", "start": 136, "end": 139, "id": 23}, {"text": "difficult", "start": 140, "end": 149, "id": 24}, {"text": "urination", "start": 150, "end": 159, "id": 25}, {"text": ".", "start": 159, "end": 160, "id": 26}, {"text": "Unenhanced", "start": 161, "end": 171, "id": 27}, {"text": "(", "start": 172, "end": 173, "id": 28}, {"text": "a", "start": 173, "end": 174, "id": 29}, {"text": ")", "start": 174, "end": 175, "id": 30}, {"text": "and", "start": 176, "end": 179, "id": 31}, {"text": "post", "start": 180, "end": 184, "id": 32}, {"text": "-", "start": 184, "end": 185, "id": 33}, {"text": "contrast", "start": 185, "end": 193, "id": 34}, {"text": "(", "start": 194, "end": 195, "id": 35}, {"text": "b", "start": 195, "end": 196, "id": 36}, {"text": ")", "start": 196, "end": 197, "id": 37}, {"text": "CT", "start": 198, "end": 200, "id": 38}, {"text": "images", "start": 201, "end": 207, "id": 39}, {"text": "showed", "start": 208, "end": 214, "id": 40}, {"text": "marked", "start": 215, "end": 221, "id": 41}, {"text": "asymmetric", "start": 222, "end": 232, "id": 42}, {"text": "solid", "start": 233, "end": 238, "id": 43}, {"text": "mural", "start": 239, "end": 244, "id": 44}, {"text": "thickening", "start": 245, "end": 255, "id": 45}, {"text": "(", "start": 256, "end": 257, "id": 46}, {"text": "*", "start": 257, "end": 258, "id": 47}, {"text": ")", "start": 258, "end": 259, "id": 48}, {"text": ",", "start": 259, "end": 260, "id": 49}, {"text": "with", "start": 261, "end": 265, "id": 50}, {"text": "poor", "start": 266, "end": 270, "id": 51}, {"text": "enhancement", "start": 271, "end": 282, "id": 52}, {"text": "along", "start": 283, "end": 288, "id": 53}, {"text": "the", "start": 289, "end": 292, "id": 54}, {"text": "anterior", "start": 293, "end": 301, "id": 55}, {"text": "right", "start": 302, "end": 307, "id": 56}, {"text": "lateral", "start": 308, "end": 315, "id": 57}, {"text": "and", "start": 316, "end": 319, "id": 58}, {"text": "superior", "start": 320, "end": 328, "id": 59}, {"text": "bladder", "start": 329, "end": 336, "id": 60}]}
{"pdf_hash": "91a1bf22f1f325b26f06ba1497f49e695fe056e0", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "FIGURE 5. A 72-year-old man with lung cancer left 8th costal bone metastasis complained of left side chest pain underwent MDCT. Axial images show destruction of the bone with soft tissue edema. Oblique axial multiplanar images show the lesions limited in posterior segment of rib with irregular cortical destruction. 3D images with more opacity show the lesions were in left 8th costal bone with irregular bone destruction. 3D \u00bc 3-dimensional, MDCT \u00bc multidetector CT.", "width": 1308, "height": 358, "subcaptions": {"a": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "b": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54], "c": [55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73]}, "subfigures": [{"id": "7ac7e6fb-b347-40b6-998e-61cdb94f3275", "label": "a", "points": [[448.4, 330.6], [448.4, -2.1], [20.7, -2.1], [20.7, 330.6]], "color": "yellow"}, {"id": "4257e726-fee0-44f6-b416-0206ff4405f5", "label": "c", "points": [[911.3, 0], [911.3, 322.4], [1289.4, 322.4], [1289.4, 0]], "color": "magenta"}, {"id": "a0ea7d81-566e-4495-86f7-cf5a7d122e49", "label": "b", "points": [[458.7, 0], [458.7, 324.4], [888.5, 324.4], [888.5, 0]], 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{"pdf_hash": "18a96f0024aca850bc650af0af5dd31642dbd960", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Posterior cervical laminar decompression and intraspinal tumor resection, followed by tumor dissection and resection through an anterior approach. (A) Female, 39 years old: MRI of the preoperative C7 schwannoma (coronal plane). (B) C6 and 7 posterior laminar decompression, partial resection of the schwannoma and partial resection of the affected right C7 nerve root (sagittal plane). (C) C7 posterior laminar decompression, partial resection of the schwannoma and partial resection of the affected right C7 nerve root (transverse plane). (D) Postoperative MRI: Phase II dumbbell-shaped giant schwannoma body resection through an anterior approach. 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{"pdf_hash": "780bd7c75d74a18194ebed5d57ee018efd210393", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: Multimodal imaging of AVL. (a) Color photograph showing an AVL associated with sparse drusen. (b) FAF reveals hyperautofluorescence corresponding to the yellowish material in the color photograph; VL is irregular and in an eccentric position related to the fovea. (c) SD-OCT shows hyperreflective material within the subretinal space. (d) FA revealing blocked fluorescence by material within the subretinal space in the early phases and staining of the AVL during the late phases of angiogram. 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{"pdf_hash": "b79a941d83bf6d91fc026a908e7b9a74dae7993c", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4 Computed tomography images of the patient undergoing ECG-gated computed tomography who showed the highest serum IgG4 level among this group (CT-case 1). Soft tissue mass encasing the abdominal aorta, and iliac and femoral arteries (A-C, arrows). Coronary arteries were normal (D-F).", "width": 654, "height": 298, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "d": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "e": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "f": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "45468d9d-6214-4c36-912d-ed7bb366f34c", "label": "a", "points": [[14.5, 4.1], [14.5, 147.7], [219, 147.7], [219, 4.1]], "color": "yellow"}, {"id": "80cd7b5a-5836-45e3-87a8-fddc4fdd0a44", "label": "b", "points": [[221.1, 147.7], [221.1, 3.1], [429.8, 3.1], [429.8, 147.7]], "color": "cyan"}, {"id": "0c75bb3b-b76d-422d-b259-b30a33370534", "label": "c", "points": [[432.9, 3.1], [432.9, 149.8], [639.6, 149.8], [639.6, 3.1]], "color": "magenta"}, {"id": "4f00e10c-f7ee-4d1e-ad99-1ce19a8e167b", "label": "d", "points": [[215.9, 152.9], [215.9, 264.5], [10.3, 264.5], [10.3, 152.9]], "color": "deepskyblue"}, {"id": "0f78356d-89ee-462d-a521-add5c6fb871c", "label": "e", "points": [[426.7, 150.8], [426.7, 263.5], [220.1, 263.5], [220.1, 150.8]], "color": "tomato"}, {"id": "d45e0969-fb0a-4c81-8300-39224b3d0b91", "label": "f", "points": [[639.6, 153.9], [639.6, 263.5], [436, 263.5], [436, 153.9]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Computed", "start": 7, "end": 15, "id": 3}, {"text": "tomography", "start": 16, "end": 26, "id": 4}, {"text": "images", "start": 27, "end": 33, "id": 5}, {"text": "of", "start": 34, "end": 36, "id": 6}, {"text": "the", "start": 37, "end": 40, "id": 7}, {"text": "patient", "start": 41, "end": 48, "id": 8}, {"text": "undergoing", "start": 49, "end": 59, "id": 9}, {"text": "ECG", "start": 60, "end": 63, "id": 10}, {"text": "-", "start": 63, "end": 64, "id": 11}, {"text": "gated", "start": 64, "end": 69, "id": 12}, {"text": "computed", "start": 70, "end": 78, "id": 13}, {"text": "tomography", "start": 79, "end": 89, "id": 14}, {"text": "who", "start": 90, "end": 93, "id": 15}, {"text": "showed", "start": 94, "end": 100, "id": 16}, {"text": "the", "start": 101, "end": 104, "id": 17}, {"text": "highest", "start": 105, "end": 112, "id": 18}, {"text": "serum", "start": 113, "end": 118, "id": 19}, {"text": "IgG4", "start": 119, "end": 123, "id": 20}, {"text": "level", "start": 124, "end": 129, "id": 21}, {"text": "among", "start": 130, "end": 135, "id": 22}, {"text": "this", "start": 136, "end": 140, "id": 23}, {"text": "group", "start": 141, "end": 146, "id": 24}, {"text": "(", "start": 147, "end": 148, "id": 25}, {"text": "CT", "start": 148, "end": 150, "id": 26}, {"text": "-", "start": 150, "end": 151, "id": 27}, {"text": "case", "start": 151, "end": 155, "id": 28}, {"text": "1", "start": 156, "end": 157, "id": 29}, {"text": ")", "start": 157, "end": 158, "id": 30}, {"text": ".", "start": 158, "end": 159, "id": 31}, {"text": "Soft", "start": 160, "end": 164, "id": 32}, {"text": "tissue", "start": 165, "end": 171, "id": 33}, {"text": "mass", "start": 172, "end": 176, "id": 34}, {"text": "encasing", "start": 177, "end": 185, "id": 35}, {"text": "the", "start": 186, "end": 189, "id": 36}, {"text": "abdominal", "start": 190, "end": 199, "id": 37}, {"text": "aorta", "start": 200, "end": 205, "id": 38}, {"text": ",", "start": 205, "end": 206, "id": 39}, {"text": "and", "start": 207, "end": 210, "id": 40}, {"text": "iliac", "start": 211, "end": 216, "id": 41}, {"text": "and", "start": 217, "end": 220, "id": 42}, {"text": "femoral", "start": 221, "end": 228, "id": 43}, {"text": "arteries", "start": 229, "end": 237, "id": 44}, {"text": "(", "start": 238, "end": 239, "id": 45}, {"text": "A", "start": 239, "end": 240, "id": 46}, {"text": "-", "start": 240, "end": 241, "id": 47}, {"text": "C", "start": 241, "end": 242, "id": 48}, {"text": ",", "start": 242, "end": 243, "id": 49}, {"text": "arrows", "start": 244, "end": 250, "id": 50}, {"text": ")", "start": 250, "end": 251, "id": 51}, {"text": ".", "start": 251, "end": 252, "id": 52}, {"text": "Coronary", "start": 253, "end": 261, "id": 53}, {"text": "arteries", "start": 262, "end": 270, "id": 54}, {"text": "were", "start": 271, "end": 275, "id": 55}, {"text": "normal", "start": 276, "end": 282, "id": 56}, {"text": "(", "start": 283, "end": 284, "id": 57}, {"text": "D", "start": 284, "end": 285, "id": 58}, {"text": "-", "start": 285, "end": 286, "id": 59}, {"text": "F", "start": 286, "end": 287, "id": 60}, {"text": ")", "start": 287, "end": 288, "id": 61}, {"text": ".", "start": 288, "end": 289, "id": 62}]}
{"pdf_hash": "b7ddcc39f36de6cc9d6ed72fb31e962a91c2a678", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig. 3. Label-free 3D molecular imaging of tumor presentation with DESI\u2013MS. (a) 3D visualization of DESI\u2013MSI results over MRI segmented tumor volume for surgical case 41. The MRI was acquired pre-operatively, and the tumor segmented and modeled using Slicer 4.0. Inset shows the overall tumor volume in light green. The position of each stereotactic sample was digitally registered to the pre-operative MRI using BrainLab iplan cranial 3.0, and the corresponding 3 dimensional coordinates used to render the distribution of the DESI\u2013MSI analyses in the 3D tumor volume. The warm color scale from yellow to red represents the relative intensity of the peak at m/z 682.7. (b) Results are further visualized on axial sections of post-contrast T1 MR images. (c) Intensity values of the peak at m/z 682.7 for each surgical sample and autopsy. Arrow shows the dural tail. S, superior; A, anterior; L, lateral; P, posterior. 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{"pdf_hash": "07be4cabb2a62d7be1dc72b0037600eb21c90b38", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Pancreatic images of type 1 AIP (cited from ref. 1 with permission). a. Dynamic CT shows diffuse swelling of the pancreas with late phase enhancement and low-density rim. b. Endoscopic pancreatography shows diffusely irregular narrowing of the main pancreatic duct. c. Endoscopic cholangiography shows beaded like and long stenotic biliary duct similar to primary sclerosing cholangitis.", "width": 976, "height": 578, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51], "c": [52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "aa45850a-8834-43ee-9222-297f7295e1bd", "label": "a", "points": [[12.6, 6.7], [12.6, 199.4], [482.9, 199.4], [482.9, 6.7]], "color": "yellow"}, {"id": "75d4bc4f-dcc8-413f-b5a3-04d31781c8f4", "label": "b", "points": [[24.9, 204], [24.9, 543.3], [486, 543.3], [486, 204]], "color": "cyan"}, {"id": "34a451c8-f821-41c5-954e-3eaddaa1dff1", "label": "c", "points": [[516.8, 105.4], [516.8, 440], [950.1, 440], [950.1, 105.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Pancreatic", "start": 8, "end": 18, "id": 4}, {"text": "images", "start": 19, "end": 25, "id": 5}, {"text": "of", "start": 26, "end": 28, "id": 6}, {"text": "type", "start": 29, "end": 33, "id": 7}, {"text": "1", "start": 34, "end": 35, "id": 8}, {"text": "AIP", "start": 36, "end": 39, "id": 9}, {"text": "(", "start": 40, "end": 41, "id": 10}, {"text": "cited", "start": 41, "end": 46, "id": 11}, {"text": "from", "start": 47, "end": 51, "id": 12}, {"text": "ref", "start": 52, "end": 55, "id": 13}, {"text": ".", "start": 55, "end": 56, "id": 14}, {"text": "1", "start": 57, "end": 58, "id": 15}, {"text": "with", "start": 59, "end": 63, "id": 16}, {"text": "permission", "start": 64, "end": 74, "id": 17}, {"text": ")", "start": 74, "end": 75, "id": 18}, {"text": ".", "start": 75, "end": 76, "id": 19}, {"text": "a.", "start": 77, "end": 79, "id": 20}, {"text": "Dynamic", "start": 80, "end": 87, "id": 21}, {"text": "CT", "start": 88, "end": 90, "id": 22}, {"text": "shows", "start": 91, "end": 96, "id": 23}, {"text": "diffuse", "start": 97, "end": 104, "id": 24}, {"text": "swelling", "start": 105, "end": 113, "id": 25}, {"text": "of", "start": 114, "end": 116, "id": 26}, {"text": "the", "start": 117, "end": 120, "id": 27}, {"text": "pancreas", "start": 121, "end": 129, "id": 28}, {"text": "with", "start": 130, "end": 134, "id": 29}, {"text": "late", "start": 135, "end": 139, "id": 30}, {"text": "phase", "start": 140, "end": 145, "id": 31}, {"text": "enhancement", "start": 146, "end": 157, "id": 32}, {"text": "and", "start": 158, "end": 161, "id": 33}, {"text": "low", "start": 162, "end": 165, "id": 34}, {"text": "-", "start": 165, "end": 166, "id": 35}, {"text": "density", "start": 166, "end": 173, "id": 36}, {"text": "rim", "start": 174, "end": 177, "id": 37}, {"text": ".", "start": 177, "end": 178, "id": 38}, {"text": "b.", "start": 179, "end": 181, "id": 39}, {"text": "Endoscopic", "start": 182, "end": 192, "id": 40}, {"text": "pancreatography", "start": 193, "end": 208, "id": 41}, {"text": "shows", "start": 209, "end": 214, "id": 42}, {"text": "diffusely", "start": 215, "end": 224, "id": 43}, {"text": "irregular", "start": 225, "end": 234, "id": 44}, {"text": "narrowing", "start": 235, "end": 244, "id": 45}, {"text": "of", "start": 245, "end": 247, "id": 46}, {"text": "the", "start": 248, "end": 251, "id": 47}, {"text": "main", "start": 252, "end": 256, "id": 48}, {"text": "pancreatic", "start": 257, "end": 267, "id": 49}, {"text": "duct", "start": 268, "end": 272, "id": 50}, {"text": ".", "start": 272, "end": 273, "id": 51}, {"text": "c.", "start": 274, "end": 276, "id": 52}, {"text": "Endoscopic", "start": 277, "end": 287, "id": 53}, {"text": "cholangiography", "start": 288, "end": 303, "id": 54}, {"text": "shows", "start": 304, "end": 309, "id": 55}, {"text": "beaded", "start": 310, "end": 316, "id": 56}, {"text": "like", "start": 317, "end": 321, "id": 57}, {"text": "and", "start": 322, "end": 325, "id": 58}, {"text": "long", "start": 326, "end": 330, "id": 59}, {"text": "stenotic", "start": 331, "end": 339, "id": 60}, {"text": "biliary", "start": 340, "end": 347, "id": 61}, {"text": "duct", "start": 348, "end": 352, "id": 62}, {"text": "similar", "start": 353, "end": 360, "id": 63}, {"text": "to", "start": 361, "end": 363, "id": 64}, {"text": "primary", "start": 364, "end": 371, "id": 65}, {"text": "sclerosing", "start": 372, "end": 382, "id": 66}, {"text": "cholangitis", "start": 383, "end": 394, "id": 67}, {"text": ".", "start": 394, "end": 395, "id": 68}]}
{"pdf_hash": "58f876b96e60b91b1e6eb8489082fd7c52ff0529", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Findings of the computed tomography analysis. (A) A multilobulated cystic mass was observed to extend into the pelvic cavity. (B) This mass originated from the lesser omentum, including the truncal vagus.", "width": 982, "height": 1202, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "88ac1733-e3b2-4d0e-9c49-3339d2623daf", "label": "a", "points": [[4.7, 6], [4.7, 725.7], [468.5, 725.7], [468.5, 6]], "color": "yellow"}, {"id": "43da400c-ae27-4645-b500-91991b723e61", "label": "b", "points": [[480.9, 2.8], [480.9, 722.6], [978.9, 722.6], [978.9, 2.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Findings", "start": 8, "end": 16, "id": 4}, {"text": "of", "start": 17, "end": 19, "id": 5}, {"text": "the", "start": 20, "end": 23, "id": 6}, {"text": "computed", "start": 24, "end": 32, "id": 7}, {"text": "tomography", "start": 33, "end": 43, "id": 8}, {"text": "analysis", "start": 44, "end": 52, "id": 9}, {"text": ".", "start": 52, "end": 53, "id": 10}, {"text": "(", "start": 54, "end": 55, "id": 11}, {"text": "A", "start": 55, "end": 56, "id": 12}, {"text": ")", "start": 56, "end": 57, "id": 13}, {"text": "A", "start": 58, "end": 59, "id": 14}, {"text": "multilobulated", "start": 60, "end": 74, "id": 15}, {"text": "cystic", "start": 75, "end": 81, "id": 16}, {"text": "mass", "start": 82, "end": 86, "id": 17}, {"text": "was", "start": 87, "end": 90, "id": 18}, {"text": "observed", "start": 91, "end": 99, "id": 19}, {"text": "to", "start": 100, "end": 102, "id": 20}, {"text": "extend", "start": 103, "end": 109, "id": 21}, {"text": "into", "start": 110, "end": 114, "id": 22}, {"text": "the", "start": 115, "end": 118, "id": 23}, {"text": "pelvic", "start": 119, "end": 125, "id": 24}, {"text": "cavity", "start": 126, "end": 132, "id": 25}, {"text": ".", "start": 132, "end": 133, "id": 26}, {"text": "(", "start": 134, "end": 135, "id": 27}, {"text": "B", "start": 135, "end": 136, "id": 28}, {"text": ")", "start": 136, "end": 137, "id": 29}, {"text": "This", "start": 138, "end": 142, "id": 30}, {"text": "mass", "start": 143, "end": 147, "id": 31}, {"text": "originated", "start": 148, "end": 158, "id": 32}, {"text": "from", "start": 159, "end": 163, "id": 33}, {"text": "the", "start": 164, "end": 167, "id": 34}, {"text": "lesser", "start": 168, "end": 174, "id": 35}, {"text": "omentum", "start": 175, "end": 182, "id": 36}, {"text": ",", "start": 182, "end": 183, "id": 37}, {"text": "including", "start": 184, "end": 193, "id": 38}, {"text": "the", "start": 194, "end": 197, "id": 39}, {"text": "truncal", "start": 198, "end": 205, "id": 40}, {"text": "vagus", "start": 206, "end": 211, "id": 41}, {"text": ".", "start": 211, "end": 212, "id": 42}]}
{"pdf_hash": "866ad9436ec5d3888885660b66c8ffef731a3d93", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 63 years-old female with GBM. MRI at diagnosis (upper row) and first recurrence (lower row). At diagnosis a left parieto-occipital mass was found, hyperintense in T2 FLAIR (arrow in a) and with irregular peripheral enhancement with central necrosis in T1Gd (arrow in b), with normal left temporal lobe (c and d). 13 months after surgery there was no evidence of recurrence at the surgical", "width": 1354, "height": 792, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23, 24, 25]}, "subfigures": [{"id": "8f253907-a54c-43d1-b831-a97df9f58605", "label": "a", "points": [[3.3, 4.8], [3.3, 400], [329.4, 400], [329.4, 4.8]], "color": "yellow"}, {"id": "88334840-b759-4ed6-a8bd-df29e8f749e6", "label": "b", "points": [[344.5, 7], [344.5, 400], [664.1, 400], [664.1, 7]], "color": "cyan"}, {"id": "372aee80-8b9a-4a1f-a3ed-abdb301c9fe1", "label": "c", "points": [[681.4, 4.8], [681.4, 393.5], [1011.8, 393.5], [1011.8, 4.8]], "color": "magenta"}, {"id": "92a1d44d-e6ff-47cf-9bf7-b22b5778eb7e", "label": "d", "points": [[1031.2, 2.6], [1031.2, 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{"pdf_hash": "ea8afe45c9f077813b389b4bf9936ff939af29b1", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 A typical FDG-PET image (a) and CT (b) of a noninvasive thymoma, patient no.12, 45 -55 min after injection of 4.5 mCi (167 MBq) of FDG, showing a low FDG uptake by tumour (DUR: 2.63).", "width": 650, "height": 904, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10], "b": [12, 13, 14, 15]}, "subfigures": [{"id": "445f0037-b759-4ab2-9ff9-c555750f189e", "label": "a", "points": [[4.3, 5.5], [4.3, 470.6], [649.1, 470.6], [649.1, 5.5]], "color": "yellow"}, {"id": "947ef969-eb9c-4c46-8441-9d14b2cbc268", "label": "b", "points": [[40.2, 514.8], [40.2, 904], [607, 904], [607, 514.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "A", "start": 9, "end": 10, "id": 2}, {"text": "typical", "start": 11, "end": 18, "id": 3}, {"text": "FDG", "start": 19, "end": 22, "id": 4}, {"text": "-", "start": 22, "end": 23, "id": 5}, {"text": "PET", "start": 23, "end": 26, "id": 6}, {"text": "image", "start": 27, "end": 32, "id": 7}, {"text": "(", "start": 33, "end": 34, "id": 8}, {"text": "a", "start": 34, "end": 35, "id": 9}, {"text": ")", "start": 35, "end": 36, "id": 10}, {"text": "and", "start": 37, "end": 40, "id": 11}, {"text": "CT", "start": 41, "end": 43, "id": 12}, {"text": "(", "start": 44, "end": 45, "id": 13}, {"text": "b", "start": 45, "end": 46, "id": 14}, {"text": ")", "start": 46, "end": 47, "id": 15}, {"text": "of", "start": 48, "end": 50, "id": 16}, {"text": "a", "start": 51, "end": 52, "id": 17}, {"text": "noninvasive", "start": 53, "end": 64, "id": 18}, {"text": "thymoma", "start": 65, "end": 72, "id": 19}, {"text": ",", "start": 72, "end": 73, "id": 20}, {"text": "patient", "start": 74, "end": 81, "id": 21}, {"text": "no.12", "start": 82, "end": 87, "id": 22}, {"text": ",", "start": 87, "end": 88, "id": 23}, {"text": "45", "start": 89, "end": 91, "id": 24}, {"text": "-55", "start": 92, "end": 95, "id": 25}, {"text": "min", "start": 96, "end": 99, "id": 26}, {"text": "after", "start": 100, "end": 105, "id": 27}, {"text": "injection", "start": 106, "end": 115, "id": 28}, {"text": "of", "start": 116, "end": 118, "id": 29}, {"text": "4.5", "start": 119, "end": 122, "id": 30}, {"text": "mCi", "start": 123, "end": 126, "id": 31}, {"text": "(", "start": 127, "end": 128, "id": 32}, {"text": "167", "start": 128, "end": 131, "id": 33}, {"text": "MBq", "start": 132, "end": 135, "id": 34}, {"text": ")", "start": 135, "end": 136, "id": 35}, {"text": "of", "start": 137, "end": 139, "id": 36}, {"text": "FDG", "start": 140, "end": 143, "id": 37}, {"text": ",", "start": 143, "end": 144, "id": 38}, {"text": "showing", "start": 145, "end": 152, "id": 39}, {"text": "a", "start": 153, "end": 154, "id": 40}, {"text": "low", "start": 155, "end": 158, "id": 41}, {"text": "FDG", "start": 159, "end": 162, "id": 42}, {"text": "uptake", "start": 163, "end": 169, "id": 43}, {"text": "by", "start": 170, "end": 172, "id": 44}, {"text": "tumour", "start": 173, "end": 179, "id": 45}, {"text": "(", "start": 180, "end": 181, "id": 46}, {"text": "DUR", "start": 181, "end": 184, "id": 47}, {"text": ":", "start": 184, "end": 185, "id": 48}, {"text": "2.63", "start": 186, "end": 190, "id": 49}, {"text": ")", "start": 190, "end": 191, "id": 50}, {"text": ".", "start": 191, "end": 192, "id": 51}]}
{"pdf_hash": "30da66238e0b6e0e10914287230271a948632aea", "fig_key": "Figure7", "fig_uri": "14-Figure7-1.png", "text": "Fig 7. Pathogenicity of eq/J-K/08 H3N8 EIV in mice: A: Intercellular space with influenza virions, budding and released from surface of the degenerating cells from trachea at 3 dpi. Irregularly shaped microvilli can be seen amongst the virions X10000. B:Ultra thin section of lung at 3 dpi, showing budding of influenza virions from degenerating cell along with disintegration of nuclear envelope and loss of organelle architecture X 10000.C: Budding and release of influenza virions from surface of a degenerating cell in lung X8000.D: Fragmentation of nucleus with degeneration of endoplasmic reticulum of epithelial cells of lung at 3 dpi X8000 (n = 6).", "width": 1026, "height": 1044, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "b": [49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80], "c": [80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96], "d": [96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120]}, "subfigures": [{"id": "dfd86593-06cd-4c33-9de5-fbdb93eb1801", 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{"pdf_hash": "2e42c1aeed11376eec89ff4846531bb797fda638", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Coronary computed tomography (CT) angiography findings. (A, B) Volume rendering CT imaging and (C) multiplanar reformation image showed a single coronary artery in which the right coronary artery (RCA) originated from a branch of the left circumflex (LCx) artery with minimal possibility of chronic total occlusion of the RCA ostium with collateral supply from the LCx artery.", "width": 1370, "height": 480, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20], "c": [22, 23, 24, 25, 26, 27]}, "subfigures": [{"id": "d30e898b-252f-40a3-8762-250c2cd0a9e0", "label": "a", "points": [[1.2, 6.1], [1.2, 434.7], [442.7, 434.7], [442.7, 6.1]], "color": "yellow"}, {"id": "16c72c12-e153-4952-8291-b7b860823b59", "label": "b", "points": [[466.5, 1.8], [466.5, 443.3], [912.3, 443.3], [912.3, 1.8]], "color": "cyan"}, {"id": "abdad6b7-95ef-4925-8f23-8733602ca531", "label": "c", "points": [[933.9, 10.5], [933.9, 439], [1364.6, 439], [1364.6, 10.5]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Coronary", "start": 10, "end": 18, "id": 3}, {"text": "computed", "start": 19, "end": 27, "id": 4}, {"text": "tomography", "start": 28, "end": 38, "id": 5}, {"text": "(", "start": 39, "end": 40, "id": 6}, {"text": "CT", "start": 40, "end": 42, "id": 7}, {"text": ")", "start": 42, "end": 43, "id": 8}, {"text": "angiography", "start": 44, "end": 55, "id": 9}, {"text": "findings", "start": 56, "end": 64, "id": 10}, {"text": ".", "start": 64, "end": 65, "id": 11}, {"text": "(", "start": 66, "end": 67, "id": 12}, {"text": "A", "start": 67, "end": 68, "id": 13}, {"text": ",", "start": 68, "end": 69, "id": 14}, {"text": "B", "start": 70, "end": 71, "id": 15}, {"text": ")", "start": 71, "end": 72, "id": 16}, {"text": "Volume", "start": 73, "end": 79, "id": 17}, {"text": "rendering", "start": 80, "end": 89, "id": 18}, {"text": "CT", "start": 90, "end": 92, "id": 19}, {"text": "imaging", "start": 93, "end": 100, "id": 20}, {"text": "and", "start": 101, "end": 104, "id": 21}, {"text": "(", "start": 105, "end": 106, "id": 22}, {"text": "C", "start": 106, "end": 107, "id": 23}, {"text": ")", "start": 107, "end": 108, "id": 24}, {"text": "multiplanar", "start": 109, "end": 120, "id": 25}, {"text": "reformation", "start": 121, "end": 132, "id": 26}, {"text": "image", "start": 133, "end": 138, "id": 27}, {"text": "showed", "start": 139, "end": 145, "id": 28}, {"text": "a", "start": 146, "end": 147, "id": 29}, {"text": "single", "start": 148, "end": 154, "id": 30}, {"text": "coronary", "start": 155, "end": 163, "id": 31}, {"text": "artery", "start": 164, "end": 170, "id": 32}, {"text": "in", "start": 171, "end": 173, "id": 33}, {"text": "which", "start": 174, "end": 179, "id": 34}, {"text": "the", "start": 180, "end": 183, "id": 35}, {"text": "right", "start": 184, "end": 189, "id": 36}, {"text": "coronary", "start": 190, "end": 198, "id": 37}, {"text": "artery", "start": 199, "end": 205, "id": 38}, {"text": "(", "start": 206, "end": 207, "id": 39}, {"text": "RCA", "start": 207, "end": 210, "id": 40}, {"text": ")", "start": 210, "end": 211, "id": 41}, {"text": "originated", "start": 212, "end": 222, "id": 42}, {"text": "from", "start": 223, "end": 227, "id": 43}, {"text": "a", "start": 228, "end": 229, "id": 44}, {"text": "branch", "start": 230, "end": 236, "id": 45}, {"text": "of", "start": 237, "end": 239, "id": 46}, {"text": "the", "start": 240, "end": 243, "id": 47}, {"text": "left", "start": 244, "end": 248, "id": 48}, {"text": "circumflex", "start": 249, "end": 259, "id": 49}, {"text": "(", "start": 260, "end": 261, "id": 50}, {"text": "LCx", "start": 261, "end": 264, "id": 51}, {"text": ")", "start": 264, "end": 265, "id": 52}, {"text": "artery", "start": 266, "end": 272, "id": 53}, {"text": "with", "start": 273, "end": 277, "id": 54}, {"text": "minimal", "start": 278, "end": 285, "id": 55}, {"text": "possibility", "start": 286, "end": 297, "id": 56}, {"text": "of", "start": 298, "end": 300, "id": 57}, {"text": "chronic", "start": 301, "end": 308, "id": 58}, {"text": "total", "start": 309, "end": 314, "id": 59}, {"text": "occlusion", "start": 315, "end": 324, "id": 60}, {"text": "of", "start": 325, "end": 327, "id": 61}, {"text": "the", "start": 328, "end": 331, "id": 62}, {"text": "RCA", "start": 332, "end": 335, "id": 63}, {"text": "ostium", "start": 336, "end": 342, "id": 64}, {"text": "with", "start": 343, "end": 347, "id": 65}, {"text": "collateral", "start": 348, "end": 358, "id": 66}, {"text": "supply", "start": 359, "end": 365, "id": 67}, {"text": "from", "start": 366, "end": 370, "id": 68}, {"text": "the", "start": 371, "end": 374, "id": 69}, {"text": "LCx", "start": 375, "end": 378, "id": 70}, {"text": "artery", "start": 379, "end": 385, "id": 71}, {"text": ".", "start": 385, "end": 386, "id": 72}]}
{"pdf_hash": "6d6b9188414396d5a85bfa2e61e44558d7c8be88", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4. (a) Longitudinal ultrasound image shows a well-circumscribed and hypoechoic intratesticular lesion in a male patient with congenital adrenal hyperplasia (CAH) consistent with testicular adrenal rest tumour (TART). (b) Internal vascularity is demonstrated on colour Doppler assessment of this lesion, which is adjacent to the mediastinum testis, a relatively characteristic feature of TART (white arrow). (c) Axial image shows the relationship of the TART to the mediastinum testis (white arrow). (d) Larger hypoechoic and illdefined intratesticular mass with a focus of central macroscopic calcification in a different patient with TART secondary to CAH.", "width": 786, "height": 588, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72], "c": [73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92], "d": [93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118]}, "subfigures": [{"id": "20b3dccd-7850-44ec-85f2-d458c8f973b2", "label": "a", "points": [[26.7, 28.1], [26.7, 228.1], [364.4, 228.1], [364.4, 28.1]], "color": "yellow"}, {"id": "bdc05776-e78d-4d76-bc71-c6bb051da0e4", "label": "b", "points": [[380.6, 29.4], [380.6, 233], [764.3, 233], 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{"pdf_hash": "23b13b4f6b8d995a497bfde3a8bcb63faf32b312", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. Diffusion (A and C) and fluid attenuated inversion recovery (FLAIR) MRI (B and D) at admission day 1. High signal intensities of bilateral middle cerebellar peduncles in diffusion and FLAIR MRI (A and B) were noted. 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{"pdf_hash": "6a30d35d56d4d95f4b34d3dd0653f5c1c17372b7", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A) Preoperative radiograph; B) Root filling radiograph; C)Eighteen months follow-up radiograph", "width": 1216, "height": 594, "subcaptions": {"a": [3, 4, 5, 6, 7], "b": [8, 9, 10, 11, 12, 13], "c": [14, 15, 16, 17, 18, 19]}, "subfigures": [{"id": "757e259c-dda7-4bd1-84f0-b72674e4b432", "label": "a", "points": [[2.2, 1.3], [2.2, 560.3], [401.8, 560.3], [401.8, 1.3]], "color": "yellow"}, {"id": "47450444-f9ff-4d43-a7bb-7dfaa876ed3e", "label": "b", "points": [[409.5, 7], [409.5, 558.4], [807.2, 558.4], [807.2, 7]], "color": "cyan"}, {"id": "71bdb637-fef7-4e8a-ae2c-44e01a3a2ad3", "label": "c", "points": [[812.9, 1.3], [812.9, 560.3], [1212.5, 560.3], [1212.5, 1.3]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "Preoperative", "start": 13, "end": 25, "id": 5}, {"text": "radiograph", "start": 26, "end": 36, "id": 6}, {"text": ";", "start": 36, "end": 37, "id": 7}, {"text": "B", "start": 38, "end": 39, "id": 8}, {"text": ")", "start": 39, "end": 40, "id": 9}, {"text": "Root", "start": 41, "end": 45, "id": 10}, {"text": "filling", "start": 46, "end": 53, "id": 11}, {"text": "radiograph", "start": 54, "end": 64, "id": 12}, {"text": ";", "start": 64, "end": 65, "id": 13}, {"text": "C)Eighteen", "start": 66, "end": 76, "id": 14}, {"text": "months", "start": 77, "end": 83, "id": 15}, {"text": "follow", "start": 84, "end": 90, "id": 16}, {"text": "-", "start": 90, "end": 91, "id": 17}, {"text": "up", "start": 91, "end": 93, "id": 18}, {"text": "radiograph", "start": 94, "end": 104, "id": 19}]}
{"pdf_hash": "84fa139ffc94fa605009daaa1784553c7faf68c7", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. (A) CT scan on admission. Bilateral patchy infil trative shadows are seen in both lung fields (white arrows). The shadows demonstrate very light ground grass opacities. (B) Two weeks after the withdrawal of bucilamine, the shad ows disappeared completely.", "width": 680, "height": 920, "subcaptions": {"a": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52]}, "subfigures": [{"id": "f12f6832-add4-45c3-b102-1e870e724f73", "label": "a", "points": [[2.7, 44.9], [2.7, 234], [334.7, 234], [334.7, 44.9]], "color": "yellow"}, {"id": "c0e6d652-f955-4723-9cf6-a1fe46c670ea", "label": "a", "points": [[2.7, 243.7], [2.7, 444.5], [336.8, 444.5], [336.8, 243.7]], "color": "cyan"}, {"id": "96d747d4-2adf-449c-aacc-dc9a4e9fb2e7", "label": "a", "points": [[4.9, 458.5], [4.9, 674.4], [333.6, 674.4], [333.6, 458.5]], "color": "magenta"}, {"id": "0ccfbba2-61bf-4dd6-9f2f-0f4f28c9acad", "label": "a", "points": [[4.9, 688.9], [4.9, 917.7], [332.5, 917.7], [332.5, 688.9]], "color": "springgreen"}, {"id": "3a68b90e-1222-4943-9e2a-f66d085e78c1", "label": "b", "points": [[347.5, 44.9], [347.5, 231.9], [678.4, 231.9], [678.4, 44.9]], "color": "tomato"}, {"id": "e43446b5-2443-4e9e-bb6b-66e0f0494f7b", "label": "b", "points": [[350.8, 242.6], [350.8, 442.4], [675.2, 442.4], [675.2, 242.6]], "color": "deepskyblue"}, {"id": "9b24c738-a8dd-4cba-994b-bb18dd987b20", "label": "b", "points": [[346.5, 459.6], [346.5, 674.4], [675.2, 674.4], [675.2, 459.6]], "color": "orange"}, {"id": "fd8ddf53-70de-4505-8027-9506cf4f7fbb", "label": "b", "points": [[348.6, 691.1], [348.6, 918.8], [677.3, 918.8], [677.3, 691.1]], "color": "hotpink"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "CT", "start": 14, "end": 16, "id": 6}, {"text": "scan", "start": 17, "end": 21, "id": 7}, {"text": "on", "start": 22, "end": 24, "id": 8}, {"text": "admission", "start": 25, "end": 34, "id": 9}, {"text": ".", "start": 34, "end": 35, "id": 10}, {"text": "Bilateral", "start": 36, "end": 45, "id": 11}, {"text": "patchy", "start": 46, "end": 52, "id": 12}, {"text": "infil", "start": 53, "end": 58, "id": 13}, {"text": "trative", "start": 59, "end": 66, "id": 14}, {"text": "shadows", "start": 67, "end": 74, "id": 15}, {"text": "are", "start": 75, "end": 78, "id": 16}, {"text": "seen", "start": 79, "end": 83, "id": 17}, {"text": "in", "start": 84, "end": 86, "id": 18}, {"text": "both", "start": 87, "end": 91, "id": 19}, {"text": "lung", "start": 92, "end": 96, "id": 20}, {"text": "fields", "start": 97, "end": 103, "id": 21}, {"text": "(", "start": 104, "end": 105, "id": 22}, {"text": "white", "start": 105, "end": 110, "id": 23}, {"text": "arrows", "start": 111, "end": 117, "id": 24}, {"text": ")", "start": 117, "end": 118, "id": 25}, {"text": ".", "start": 118, "end": 119, "id": 26}, {"text": "The", "start": 120, "end": 123, "id": 27}, {"text": "shadows", "start": 124, "end": 131, "id": 28}, {"text": "demonstrate", "start": 132, "end": 143, "id": 29}, {"text": "very", "start": 144, "end": 148, "id": 30}, {"text": "light", "start": 149, "end": 154, "id": 31}, {"text": "ground", "start": 155, "end": 161, "id": 32}, {"text": "grass", "start": 162, "end": 167, "id": 33}, {"text": "opacities", "start": 168, "end": 177, "id": 34}, {"text": ".", "start": 177, "end": 178, "id": 35}, {"text": "(", "start": 179, "end": 180, "id": 36}, {"text": "B", "start": 180, "end": 181, "id": 37}, {"text": ")", "start": 181, "end": 182, "id": 38}, {"text": "Two", "start": 183, "end": 186, "id": 39}, {"text": "weeks", "start": 187, "end": 192, "id": 40}, {"text": "after", "start": 193, "end": 198, "id": 41}, {"text": "the", "start": 199, "end": 202, "id": 42}, {"text": "withdrawal", "start": 203, "end": 213, "id": 43}, {"text": "of", "start": 214, "end": 216, "id": 44}, {"text": "bucilamine", "start": 217, "end": 227, "id": 45}, {"text": ",", "start": 227, "end": 228, "id": 46}, {"text": "the", "start": 229, "end": 232, "id": 47}, {"text": "shad", "start": 233, "end": 237, "id": 48}, {"text": "ows", "start": 238, "end": 241, "id": 49}, {"text": "disappeared", "start": 242, "end": 253, "id": 50}, {"text": "completely", "start": 254, "end": 264, "id": 51}, {"text": ".", "start": 264, "end": 265, "id": 52}]}
{"pdf_hash": "8c5d1304c836177b888ed524ca04b32041e982dc", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 a\u2013d Ultrasound images of thyroid nodule in 2 patients ( a, b \u2013 patient 1 and c, d \u2013 patient 2) with histopathological diagnosis of FVPTC showing positive hypoechoic internal septae sign which is seen as ill-defined hypoechoic branching echoes within a well defined isoechoic nodule.", "width": 1334, "height": 776, "subcaptions": {"a": [15, 16, 17, 18, 19, 20], "b": [15, 16, 17, 18, 19, 20], "c": [22, 23, 24, 25, 26, 27], "d": [22, 23, 24, 25, 26, 27]}, "subfigures": [{"id": "ccc5c694-ec1a-44cb-b1b6-d15cad8efc75", "label": "a", "points": [[5.3, 6.3], [5.3, 358.3], [445.7, 358.3], [445.7, 6.3]], "color": "yellow"}, {"id": "5d6406f8-8989-4b0b-9939-8f9ebdbc46c3", "label": "c", "points": [[9.5, 366.7], [9.5, 771.3], [449.9, 771.3], [449.9, 366.7]], "color": "magenta"}, {"id": "e37c4fd6-6240-4451-ad62-8f22c1d3cc7a", "label": "b", "points": [[452, 4.2], [452, 356.2], [896.7, 356.2], [896.7, 4.2]], "color": "cyan"}, {"id": "67e24f1d-59de-431a-b0a3-59778a7a6bb8", "label": "d", "points": [[464.7, 366.7], [464.7, 769.2], [900.9, 769.2], [900.9, 366.7]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "\u2013", "start": 8, "end": 9, "id": 4}, {"text": "d", "start": 9, "end": 10, "id": 5}, {"text": "Ultrasound", "start": 11, "end": 21, "id": 6}, {"text": "images", "start": 22, "end": 28, "id": 7}, {"text": "of", "start": 29, "end": 31, "id": 8}, {"text": "thyroid", "start": 32, "end": 39, "id": 9}, {"text": "nodule", "start": 40, "end": 46, "id": 10}, {"text": "in", "start": 47, "end": 49, "id": 11}, {"text": "2", "start": 50, "end": 51, "id": 12}, {"text": "patients", "start": 52, "end": 60, "id": 13}, {"text": "(", "start": 61, "end": 62, "id": 14}, {"text": "a", "start": 63, "end": 64, "id": 15}, {"text": ",", "start": 64, "end": 65, "id": 16}, {"text": "b", "start": 66, "end": 67, "id": 17}, {"text": "\u2013", "start": 68, "end": 69, "id": 18}, {"text": "patient", "start": 70, "end": 77, "id": 19}, {"text": "1", "start": 78, "end": 79, "id": 20}, {"text": "and", "start": 80, "end": 83, "id": 21}, {"text": "c", "start": 84, "end": 85, "id": 22}, {"text": ",", "start": 85, "end": 86, "id": 23}, {"text": "d", "start": 87, "end": 88, "id": 24}, {"text": "\u2013", "start": 89, "end": 90, "id": 25}, {"text": "patient", "start": 91, "end": 98, "id": 26}, {"text": "2", "start": 99, "end": 100, "id": 27}, {"text": ")", "start": 100, "end": 101, "id": 28}, {"text": "with", "start": 102, "end": 106, "id": 29}, {"text": "histopathological", "start": 107, "end": 124, "id": 30}, {"text": "diagnosis", "start": 125, "end": 134, "id": 31}, {"text": "of", "start": 135, "end": 137, "id": 32}, {"text": "FVPTC", "start": 138, "end": 143, "id": 33}, {"text": "showing", "start": 144, "end": 151, "id": 34}, {"text": "positive", "start": 152, "end": 160, "id": 35}, {"text": "hypoechoic", "start": 161, "end": 171, "id": 36}, {"text": "internal", "start": 172, "end": 180, "id": 37}, {"text": "septae", "start": 181, "end": 187, "id": 38}, {"text": "sign", "start": 188, "end": 192, "id": 39}, {"text": "which", "start": 193, "end": 198, "id": 40}, {"text": "is", "start": 199, "end": 201, "id": 41}, {"text": "seen", "start": 202, "end": 206, "id": 42}, {"text": "as", "start": 207, "end": 209, "id": 43}, {"text": "ill", "start": 210, "end": 213, "id": 44}, {"text": "-", "start": 213, "end": 214, "id": 45}, {"text": "defined", "start": 214, "end": 221, "id": 46}, {"text": "hypoechoic", "start": 222, "end": 232, "id": 47}, {"text": "branching", "start": 233, "end": 242, "id": 48}, {"text": "echoes", "start": 243, "end": 249, "id": 49}, {"text": "within", "start": 250, "end": 256, "id": 50}, {"text": "a", "start": 257, "end": 258, "id": 51}, {"text": "well", "start": 259, "end": 263, "id": 52}, {"text": "defined", "start": 264, "end": 271, "id": 53}, {"text": "isoechoic", "start": 272, "end": 281, "id": 54}, {"text": "nodule", "start": 282, "end": 288, "id": 55}, {"text": ".", "start": 288, "end": 289, "id": 56}]}
{"pdf_hash": "43e07c61005a62f3d79e1fac30f4dcdff8f9a619", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. A. Coronal FDG-PET image before treatment. FDG accumulation was observed in the right kidney and at the midline of the lower abdomen (arrow), and in salivary glands, but not in the nasal area or pancreas. B. Coronal FDG-PET image after treatment without FDG accumulation. C. Axial FDG-PET/CT image before treatment. FDG accumulation corresponds to the soft tissue mass surrounding the abdominal aorta, i.e., retroperitoneal fibrosis. D. 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{"pdf_hash": "a472b1507829f421d646c3baf44f653def735e47", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Orbital contrast MRI of the same patient. Axial scans showed predominantly T1 hypointensity (A) and T2 hyperintensity (B) with focal T1 hyperintense and T2 hypointense foci (A and B, arrows). No demonstrable contrast enhancement was observed on the postcontrast T1-weighted image (C). 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{"pdf_hash": "018698d11b4a1a34ed26c32e3fca5885a4f6ff9b", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5. (A\u2013D) Electron micrographs of thin sections from the testicular biopsy. (A) Typical zygotene-like cell showing single axes (asterisks). Magnification: \u00d75000. (B) A terminal segment of an infrequent synaptonemal complex, showing the lateral elements (LE), the central element (CE) and the normal transverse filaments (TF). Magnification: \u00d721 000. (C) Low-magnification electron micrograph showing normal spermatogonia (SG) and leptotenes (L) and one abnormal cell division (arrowhead) near the lumen. Magnification: \u00d71900. (D) Electron micrograph of one abnormal spermatocyte division showing the absence of microtubuli, the abundant clear vacuoles and the lattice-like array of small vacuoles. 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{"pdf_hash": "7d3193ab54415da9a3eea5cbf3d8f9318df0ffd4", "fig_key": "Figure7", "fig_uri": "10-Figure7-1.png", "text": "Figure 7: Plantar fasciitis in a 64-year-old female. (a) Longitudinal ultrasound image shows fusiform thickening of the plantar fascia with loss of the normal reflectivity and fibrillar pattern. (b) Sagittal fused technetium-99m methylene diphosphonate single-photon emission computed tomography/computed tomography images of the same patient demonstrate increased entheseal uptake related to the plantar fascia origin at the os calcis b a", "width": 674, "height": 250, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73]}, "subfigures": [{"id": "acdf9e95-370f-4075-b709-6a72ba474acd", "label": "a", "points": [[2.1, 0], [2.1, 217.2], [263, 217.2], [263, 0]], "color": "yellow"}, {"id": "67bd5d0a-1ad8-46a2-817e-319bb3dcacd5", "label": "b", "points": [[270.4, 4.5], [270.4, 214.2], [668.1, 214.2], [668.1, 4.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "7", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Plantar", "start": 10, "end": 17, "id": 3}, {"text": "fasciitis", "start": 18, "end": 27, "id": 4}, {"text": "in", "start": 28, "end": 30, "id": 5}, {"text": "a", "start": 31, "end": 32, "id": 6}, {"text": "64-year", "start": 33, "end": 40, "id": 7}, {"text": "-", "start": 40, "end": 41, "id": 8}, {"text": "old", "start": 41, "end": 44, "id": 9}, {"text": "female", "start": 45, "end": 51, "id": 10}, {"text": ".", "start": 51, "end": 52, "id": 11}, {"text": "(", "start": 53, "end": 54, "id": 12}, {"text": "a", "start": 54, "end": 55, "id": 13}, {"text": ")", "start": 55, "end": 56, "id": 14}, {"text": "Longitudinal", "start": 57, "end": 69, "id": 15}, {"text": "ultrasound", "start": 70, "end": 80, "id": 16}, {"text": "image", "start": 81, "end": 86, "id": 17}, {"text": "shows", "start": 87, "end": 92, "id": 18}, {"text": "fusiform", "start": 93, "end": 101, "id": 19}, {"text": "thickening", "start": 102, "end": 112, "id": 20}, {"text": "of", "start": 113, "end": 115, "id": 21}, {"text": "the", "start": 116, "end": 119, "id": 22}, {"text": "plantar", "start": 120, "end": 127, "id": 23}, {"text": "fascia", "start": 128, "end": 134, "id": 24}, {"text": "with", "start": 135, "end": 139, "id": 25}, {"text": "loss", "start": 140, "end": 144, "id": 26}, {"text": "of", "start": 145, "end": 147, "id": 27}, {"text": "the", "start": 148, "end": 151, "id": 28}, {"text": "normal", "start": 152, "end": 158, "id": 29}, {"text": "reflectivity", "start": 159, "end": 171, "id": 30}, {"text": "and", "start": 172, "end": 175, "id": 31}, {"text": "fibrillar", "start": 176, "end": 185, "id": 32}, {"text": "pattern", "start": 186, "end": 193, "id": 33}, {"text": ".", "start": 193, "end": 194, "id": 34}, {"text": "(", "start": 195, "end": 196, "id": 35}, {"text": "b", "start": 196, "end": 197, "id": 36}, {"text": ")", "start": 197, "end": 198, "id": 37}, {"text": "Sagittal", "start": 199, "end": 207, "id": 38}, {"text": "fused", "start": 208, "end": 213, "id": 39}, {"text": "technetium-99", "start": 214, "end": 227, "id": 40}, {"text": "m", "start": 227, "end": 228, "id": 41}, {"text": "methylene", "start": 229, "end": 238, "id": 42}, {"text": "diphosphonate", "start": 239, "end": 252, "id": 43}, {"text": "single", "start": 253, "end": 259, "id": 44}, {"text": "-", "start": 259, "end": 260, "id": 45}, {"text": "photon", "start": 260, "end": 266, "id": 46}, {"text": "emission", "start": 267, "end": 275, "id": 47}, {"text": "computed", "start": 276, "end": 284, "id": 48}, {"text": "tomography", "start": 285, "end": 295, "id": 49}, {"text": "/", "start": 295, "end": 296, "id": 50}, {"text": "computed", "start": 296, "end": 304, "id": 51}, {"text": "tomography", "start": 305, "end": 315, "id": 52}, {"text": "images", "start": 316, "end": 322, "id": 53}, {"text": "of", "start": 323, "end": 325, "id": 54}, {"text": "the", "start": 326, "end": 329, "id": 55}, {"text": "same", "start": 330, "end": 334, "id": 56}, {"text": "patient", "start": 335, "end": 342, "id": 57}, {"text": "demonstrate", "start": 343, "end": 354, "id": 58}, {"text": "increased", "start": 355, "end": 364, "id": 59}, {"text": "entheseal", "start": 365, "end": 374, "id": 60}, {"text": "uptake", "start": 375, "end": 381, "id": 61}, {"text": "related", "start": 382, "end": 389, "id": 62}, {"text": "to", "start": 390, "end": 392, "id": 63}, {"text": "the", "start": 393, "end": 396, "id": 64}, {"text": "plantar", "start": 397, "end": 404, "id": 65}, {"text": "fascia", "start": 405, "end": 411, "id": 66}, {"text": "origin", "start": 412, "end": 418, "id": 67}, {"text": "at", "start": 419, "end": 421, "id": 68}, {"text": "the", "start": 422, "end": 425, "id": 69}, {"text": "os", "start": 426, "end": 428, "id": 70}, {"text": "calcis", "start": 429, "end": 435, "id": 71}, {"text": "b", "start": 436, "end": 437, "id": 72}, {"text": "a", "start": 438, "end": 439, "id": 73}]}
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{"pdf_hash": "ced7a2dde2ba9ba66ad10a5435d3ef99c2dcac1f", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. En-expressing neurons in the Johnston's Organ. A-G. mCD8::GFP (green) in the JO of P6 stage left pupal antennae, neuronal nuclei stained with Elav antibody (red), and Engrailed (En) antibody (magenta with Elav staining). A. Frontal view of en.GFP and En protein in the posterior half of the pedicel, showing En-expressing neurons (En-JONs) only in the ventral half of the posterior group. B. Anterior half of same pedicel showing en.GFP and En protein only in two large neurons. C. Transverse section through pedicel, showing medial and posterior neuronal groups (divided by dashed line). Most En-JONs are in the posterior group. D. Frontal view of JO15. GFP and En protein in the posterior half of pedicel, showing En expression in many JO15-expressing neurons. E. Anterior half of the same antenna, showing many JO15-expressing neurons, only one of which has En (arrowhead). F. Transverse section through pedicel. G. 3D views from lateral side of JO, showing 'open bowl' arrangement of Elav-positive neurons. En-JONs are present in the posterior and ventral regions of the neuronal array, with only two large neurons in the medial region (arrowheads). JO15-expressing neurons are present in both sides of the array. Ventral neurons with En protein (brackets) do not express JO15. H, I. Frontal views of posterior (H) and anterior (I) halves of pedicel with en .2xEGFP (green) and nompA-GFP (cyan or white) to label dendritic caps and threads. Cap threads of most En-JONs (cyan dashes) insert on medial side of cuticular ring (white arrow), only a few ventral En-JONs insert ventrally (white dashes). Anterior caps insert on lateral side of the ring (black arrow). I. Dorsally and ventrally inserting threads colored white. Ventral En-JONs encircled with white dots. Dorsal (D), lateral (L), and anterior (A) axes are indicated by arrows. 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{"pdf_hash": "d2cb3f2d2bbb9420520f23c8defc01c82627f2e9", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Cre-mediated recombination in [Tie2-Cre: sGFP] embryos. (A): Activation of green fluorescent protein in the vasculature network of the E9.5 embryo. (B, C): Magnified images of intersomitic vascular network and yolk sac vascular network. (D-F): Transverse sections of E10.5 embryo through the aorta-gonad-mesonephros region. (D): Anti-Tie2 antibody staining (green); (E) anti-Cre-recombinase antibody staining (red); (F) merged (D) and (E) and 4 0 ,6-diamidino-2-phenylindole staining (blue, not shown) images. Note lateral (arrowhead) and ventral (arrow) intra-aortic clusters. (G): Magnified image of the lateral intra-aortic cluster shown in (F) by arrowhead. 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{"pdf_hash": "06801e39b5c3c6a2e03492d4f36ddf32533747e2", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2 Four-chamber view of the transthoracic echocardiogram (TTE).\u00a0Left: diastolic phase; right, systolic phase. TTE described akinesis of the mid to apical portions of both the left and right ventricles.", "width": 686, "height": 280, "subcaptions": {"a": [15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24]}, "subfigures": [{"id": "827b7a5d-3363-43e5-afc0-095f91c45d41", "label": "a", "points": [[4.9, 4.2], [4.9, 244.7], [331.1, 244.7], [331.1, 4.2]], "color": "yellow"}, {"id": "a777fff7-7786-4341-b20f-c265f6b69716", "label": "b", "points": [[337.6, 3.1], [337.6, 244.7], [685.5, 244.7], [685.5, 3.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Four", "start": 9, "end": 13, "id": 2}, {"text": "-", "start": 13, "end": 14, "id": 3}, {"text": "chamber", "start": 14, "end": 21, "id": 4}, {"text": "view", "start": 22, "end": 26, "id": 5}, {"text": "of", "start": 27, "end": 29, "id": 6}, {"text": "the", "start": 30, "end": 33, "id": 7}, {"text": "transthoracic", "start": 34, "end": 47, "id": 8}, {"text": "echocardiogram", "start": 48, "end": 62, "id": 9}, {"text": "(", "start": 63, "end": 64, "id": 10}, {"text": "TTE", "start": 64, "end": 67, "id": 11}, {"text": ")", "start": 67, "end": 68, "id": 12}, {"text": ".", "start": 68, "end": 69, "id": 13}, {"text": "\u00a0", "start": 69, "end": 70, "id": 14}, {"text": "Left", "start": 70, "end": 74, "id": 15}, {"text": ":", "start": 74, "end": 75, "id": 16}, {"text": "diastolic", "start": 76, "end": 85, "id": 17}, {"text": "phase", "start": 86, "end": 91, "id": 18}, {"text": ";", "start": 91, "end": 92, "id": 19}, {"text": "right", "start": 93, "end": 98, "id": 20}, {"text": ",", "start": 98, "end": 99, "id": 21}, {"text": "systolic", "start": 100, "end": 108, "id": 22}, {"text": "phase", "start": 109, "end": 114, "id": 23}, {"text": ".", "start": 114, "end": 115, "id": 24}, {"text": "TTE", "start": 116, "end": 119, "id": 25}, {"text": "described", "start": 120, "end": 129, "id": 26}, {"text": "akinesis", "start": 130, "end": 138, "id": 27}, {"text": "of", "start": 139, "end": 141, "id": 28}, {"text": "the", "start": 142, "end": 145, "id": 29}, {"text": "mid", "start": 146, "end": 149, "id": 30}, {"text": "to", "start": 150, "end": 152, "id": 31}, {"text": "apical", "start": 153, "end": 159, "id": 32}, {"text": "portions", "start": 160, "end": 168, "id": 33}, {"text": "of", "start": 169, "end": 171, "id": 34}, {"text": "both", "start": 172, "end": 176, "id": 35}, {"text": "the", "start": 177, "end": 180, "id": 36}, {"text": "left", "start": 181, "end": 185, "id": 37}, {"text": "and", "start": 186, "end": 189, "id": 38}, {"text": "right", "start": 190, "end": 195, "id": 39}, {"text": "ventricles", "start": 196, "end": 206, "id": 40}, {"text": ".", "start": 206, "end": 207, "id": 41}]}
{"pdf_hash": "6bc544fc642934ad5550cd3fc1487e0b580c5612", "fig_key": "Figure2", "fig_uri": "1-Figure2-1.png", "text": "Figure 2. Sagittal T2-weighted MRI sequence (A) and contrast-enhanced sagittal T1-weighted MRI sequence (B) showing an intradural extramedullary lesion in the lower dorsal spine, with elevated signal intensity on the T2-weighted sequence (arrow) and intense contrast enhancement (arrowhead), consistent with leptomeningeal involvement.", "width": 1090, "height": 554, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9], "b": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20]}, "subfigures": [{"id": "9aab7ccf-7b2c-4d09-9aab-fd33acd3378f", "label": "a", "points": [[-0.9, 1.7], [-0.9, 545.9], [531.2, 545.9], [531.2, 1.7]], "color": "yellow"}, {"id": "3101f8f6-0fc8-4d6a-b17d-81ed61687cfa", "label": "b", "points": [[538.1, 3.4], [538.1, 552.8], [1061.6, 552.8], [1061.6, 3.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Sagittal", "start": 10, "end": 18, "id": 3}, {"text": "T2-weighted", "start": 19, "end": 30, "id": 4}, {"text": "MRI", "start": 31, "end": 34, "id": 5}, {"text": "sequence", "start": 35, "end": 43, "id": 6}, {"text": "(", "start": 44, "end": 45, "id": 7}, {"text": "A", "start": 45, "end": 46, "id": 8}, {"text": ")", "start": 46, "end": 47, "id": 9}, {"text": "and", "start": 48, "end": 51, "id": 10}, {"text": "contrast", "start": 52, "end": 60, "id": 11}, {"text": "-", "start": 60, "end": 61, "id": 12}, {"text": "enhanced", "start": 61, "end": 69, "id": 13}, {"text": "sagittal", "start": 70, "end": 78, "id": 14}, {"text": "T1-weighted", "start": 79, "end": 90, "id": 15}, {"text": "MRI", "start": 91, "end": 94, "id": 16}, {"text": "sequence", "start": 95, "end": 103, "id": 17}, {"text": "(", "start": 104, "end": 105, "id": 18}, {"text": "B", "start": 105, "end": 106, "id": 19}, {"text": ")", "start": 106, "end": 107, "id": 20}, {"text": "showing", "start": 108, "end": 115, "id": 21}, {"text": "an", "start": 116, "end": 118, "id": 22}, {"text": "intradural", "start": 119, "end": 129, "id": 23}, {"text": "extramedullary", "start": 130, "end": 144, "id": 24}, {"text": "lesion", "start": 145, "end": 151, "id": 25}, {"text": "in", "start": 152, "end": 154, "id": 26}, {"text": "the", "start": 155, "end": 158, "id": 27}, {"text": "lower", "start": 159, "end": 164, "id": 28}, {"text": "dorsal", "start": 165, "end": 171, "id": 29}, {"text": "spine", "start": 172, "end": 177, "id": 30}, {"text": ",", "start": 177, "end": 178, "id": 31}, {"text": "with", "start": 179, "end": 183, "id": 32}, {"text": "elevated", "start": 184, "end": 192, "id": 33}, {"text": "signal", "start": 193, "end": 199, "id": 34}, {"text": "intensity", "start": 200, "end": 209, "id": 35}, {"text": "on", "start": 210, "end": 212, "id": 36}, {"text": "the", "start": 213, "end": 216, "id": 37}, {"text": "T2-weighted", "start": 217, "end": 228, "id": 38}, {"text": "sequence", "start": 229, "end": 237, "id": 39}, {"text": "(", "start": 238, "end": 239, "id": 40}, {"text": "arrow", "start": 239, "end": 244, "id": 41}, {"text": ")", "start": 244, "end": 245, "id": 42}, {"text": "and", "start": 246, "end": 249, "id": 43}, {"text": "intense", "start": 250, "end": 257, "id": 44}, {"text": "contrast", "start": 258, "end": 266, "id": 45}, {"text": "enhancement", "start": 267, "end": 278, "id": 46}, {"text": "(", "start": 279, "end": 280, "id": 47}, {"text": "arrowhead", "start": 280, "end": 289, "id": 48}, {"text": ")", "start": 289, "end": 290, "id": 49}, {"text": ",", "start": 290, "end": 291, "id": 50}, {"text": "consistent", "start": 292, "end": 302, "id": 51}, {"text": "with", "start": 303, "end": 307, "id": 52}, {"text": "leptomeningeal", "start": 308, "end": 322, "id": 53}, {"text": "involvement", "start": 323, "end": 334, "id": 54}, {"text": ".", "start": 334, "end": 335, "id": 55}]}
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{"pdf_hash": "59927398b6e24d5fb5932789bd062330e8dd50ee", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Technetium\u201399m-ethylcysteinate dimer single photon emission computed tomography scans, before treatment (A) showing diffuse hypoperfusion in the left frontal lobe, and after treatment (B) demonstrating improved cerebral blood flow in the left frontal lobe.", "width": 552, "height": 638, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 29, 30, 31]}, "subfigures": [{"id": "d026b8ab-5905-4f2a-8a34-4c0f7d8223be", "label": "a", "points": [[4, 3], [4, 306], [547, 306], [547, 3]], "color": "yellow"}, {"id": "eff8c8c0-a57d-4b40-b66b-ba8ba29c2f14", "label": "b", "points": [[2, 320], [2, 634], [549, 634], [549, 320]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Technetium\u201399m", "start": 7, "end": 21, "id": 3}, {"text": "-", "start": 21, "end": 22, "id": 4}, {"text": "ethylcysteinate", "start": 22, "end": 37, "id": 5}, {"text": "dimer", "start": 38, "end": 43, "id": 6}, {"text": "single", "start": 44, "end": 50, "id": 7}, {"text": "photon", "start": 51, "end": 57, "id": 8}, {"text": "emission", "start": 58, "end": 66, "id": 9}, {"text": "computed", "start": 67, "end": 75, "id": 10}, {"text": "tomography", "start": 76, "end": 86, "id": 11}, {"text": "scans", "start": 87, "end": 92, "id": 12}, {"text": ",", "start": 92, "end": 93, "id": 13}, {"text": "before", "start": 94, "end": 100, "id": 14}, {"text": "treatment", "start": 101, "end": 110, "id": 15}, {"text": "(", "start": 111, "end": 112, "id": 16}, {"text": "A", "start": 112, "end": 113, "id": 17}, {"text": ")", "start": 113, "end": 114, "id": 18}, {"text": "showing", "start": 115, "end": 122, "id": 19}, {"text": "diffuse", "start": 123, "end": 130, "id": 20}, {"text": "hypoperfusion", "start": 131, "end": 144, "id": 21}, {"text": "in", "start": 145, "end": 147, "id": 22}, {"text": "the", "start": 148, "end": 151, "id": 23}, {"text": "left", "start": 152, "end": 156, "id": 24}, {"text": "frontal", "start": 157, "end": 164, "id": 25}, {"text": "lobe", "start": 165, "end": 169, "id": 26}, {"text": ",", "start": 169, "end": 170, "id": 27}, {"text": "and", "start": 171, "end": 174, "id": 28}, {"text": "after", "start": 175, "end": 180, "id": 29}, {"text": "treatment", "start": 181, "end": 190, "id": 30}, {"text": "(", "start": 191, "end": 192, "id": 31}, {"text": "B", "start": 192, "end": 193, "id": 32}, {"text": ")", "start": 193, "end": 194, "id": 33}, {"text": "demonstrating", "start": 195, "end": 208, "id": 34}, {"text": "improved", "start": 209, "end": 217, "id": 35}, {"text": "cerebral", "start": 218, "end": 226, "id": 36}, {"text": "blood", "start": 227, "end": 232, "id": 37}, {"text": "flow", "start": 233, "end": 237, "id": 38}, {"text": "in", "start": 238, "end": 240, "id": 39}, {"text": "the", "start": 241, "end": 244, "id": 40}, {"text": "left", "start": 245, "end": 249, "id": 41}, {"text": "frontal", "start": 250, "end": 257, "id": 42}, {"text": "lobe", "start": 258, "end": 262, "id": 43}, {"text": ".", "start": 262, "end": 263, "id": 44}]}
{"pdf_hash": "f09883b4bcff78498ee11c36d693865353eabe19", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIGURE 2. Contrast-enhanced neck CT scan. An over distension state of the upper (cervical) trachea and adjacent soft tissue with air bubbles around the trachea, the right thyroid gland, and both visceral spaces are shown (A and B). 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{"pdf_hash": "8bdc7e9940868cc0c20e3accc5d48920c1881b50", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Positron emission tomography\u9104 computed tomography (PET\u9104 CT) or CT results of lungs and pericardium prior to chemotherapy (A, B), after 2 cycles of chemotherapy (C, D) and 6 cycles of chemotherapy (E, F) Significant reduction of the tumor volume was observed.", "width": 1286, "height": 612, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25], "b": [18, 19, 20, 21, 22, 23, 24, 25], "c": [32, 33, 34, 35, 36, 27, 28, 29, 30, 31], "d": [32, 33, 34, 35, 36, 27, 28, 29, 30, 31], "e": [38, 39, 40, 41, 42, 43, 44, 45, 46], "f": [38, 39, 40, 41, 42, 43, 44, 45, 46]}, "subfigures": [{"id": "a399e329-6e71-46de-9e85-cbe90eaa8fda", "label": "a", "points": [[7.7, 3.7], [7.7, 280], [414, 280], [414, 3.7]], "color": "yellow"}, {"id": "146518e1-a130-41d5-bd19-ec1eb9d1564f", "label": "b", "points": [[422.1, -0.3], [422.1, 280], [838.6, 280], [838.6, -0.3]], "color": "cyan"}, {"id": "21e79eec-d156-4751-b59f-f1f31ca6a57f", "label": "c", "points": [[850.8, -0.3], [850.8, 284.1], [1275.4, 284.1], [1275.4, -0.3]], "color": "magenta"}, {"id": "ae3fd901-1807-49fe-95d0-db68e0e2a90a", "label": "d", "points": [[-0.4, 294.2], [-0.4, 586.8], [405.9, 586.8], [405.9, 294.2]], "color": "springgreen"}, {"id": "4d58f6cf-7d52-4e1d-af20-f0b34a00e70e", "label": "e", "points": [[428.2, 292.2], [428.2, 578.7], [838.6, 578.7], [838.6, 292.2]], "color": "tomato"}, {"id": "0acbc992-55b5-419b-8cfd-24e412555786", "label": "f", "points": [[852.8, 294.2], [852.8, 586.8], [1281.5, 586.8], [1281.5, 294.2]], "color": "deepskyblue"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Positron", "start": 9, "end": 17, "id": 2}, {"text": "emission", "start": 18, "end": 26, "id": 3}, {"text": "tomography\u9104", "start": 27, "end": 38, "id": 4}, {"text": "computed", "start": 39, "end": 47, "id": 5}, {"text": "tomography", "start": 48, "end": 58, "id": 6}, {"text": "(", "start": 59, "end": 60, "id": 7}, {"text": "PET\u9104", "start": 60, "end": 64, "id": 8}, {"text": "CT", "start": 65, "end": 67, "id": 9}, {"text": ")", "start": 67, "end": 68, "id": 10}, {"text": "or", "start": 69, "end": 71, "id": 11}, {"text": "CT", "start": 72, "end": 74, "id": 12}, {"text": "results", "start": 75, "end": 82, "id": 13}, {"text": "of", "start": 83, "end": 85, "id": 14}, {"text": "lungs", "start": 86, "end": 91, "id": 15}, {"text": "and", "start": 92, "end": 95, "id": 16}, {"text": "pericardium", "start": 96, "end": 107, "id": 17}, {"text": "prior", "start": 108, "end": 113, "id": 18}, {"text": "to", "start": 114, "end": 116, "id": 19}, {"text": "chemotherapy", "start": 117, "end": 129, "id": 20}, {"text": "(", "start": 130, "end": 131, "id": 21}, {"text": "A", "start": 131, "end": 132, "id": 22}, {"text": ",", "start": 132, "end": 133, "id": 23}, {"text": "B", "start": 134, "end": 135, "id": 24}, {"text": ")", "start": 135, "end": 136, "id": 25}, {"text": ",", "start": 136, "end": 137, "id": 26}, {"text": "after", "start": 138, "end": 143, "id": 27}, {"text": "2", "start": 144, "end": 145, "id": 28}, {"text": "cycles", "start": 146, "end": 152, "id": 29}, {"text": "of", "start": 153, "end": 155, "id": 30}, {"text": "chemotherapy", "start": 156, "end": 168, "id": 31}, {"text": "(", "start": 169, "end": 170, "id": 32}, {"text": "C", "start": 170, "end": 171, "id": 33}, {"text": ",", "start": 171, "end": 172, "id": 34}, {"text": "D", "start": 173, "end": 174, "id": 35}, {"text": ")", "start": 174, "end": 175, "id": 36}, {"text": "and", "start": 176, "end": 179, "id": 37}, {"text": "6", "start": 180, "end": 181, "id": 38}, {"text": "cycles", "start": 182, "end": 188, "id": 39}, {"text": "of", "start": 189, "end": 191, "id": 40}, {"text": "chemotherapy", "start": 192, "end": 204, "id": 41}, {"text": "(", "start": 205, "end": 206, "id": 42}, {"text": "E", "start": 206, "end": 207, "id": 43}, {"text": ",", "start": 207, "end": 208, "id": 44}, {"text": "F", "start": 209, "end": 210, "id": 45}, {"text": ")", "start": 210, "end": 211, "id": 46}, {"text": "Significant", "start": 212, "end": 223, "id": 47}, {"text": "reduction", "start": 224, "end": 233, "id": 48}, {"text": "of", "start": 234, "end": 236, "id": 49}, {"text": "the", "start": 237, "end": 240, "id": 50}, {"text": "tumor", "start": 241, "end": 246, "id": 51}, {"text": "volume", "start": 247, "end": 253, "id": 52}, {"text": "was", "start": 254, "end": 257, "id": 53}, {"text": "observed", "start": 258, "end": 266, "id": 54}, {"text": ".", "start": 266, "end": 267, "id": 55}]}
{"pdf_hash": "fada941a28855200171e8305113e4ea95dd03ee5", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. (A) Endoscopy findings. A 1-cm polypoid lesion covered by exudates is observed just above the esophagogastric junction. (B) Endosonographic findings. A homogeneously hyperechoic lesion is seen in the submucosa. (C) Saline solution is injected to lift the lesion. (D) Complete removal of the lesion using a snare. (E) Resected specimen. (F) Histological findings. 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{"pdf_hash": "39651615f1057270e2ee7ddc82d7bba4b883211d", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Fig. 1 Tissue-restricted transgenic expression of Cre recombinase in neural crest and endothelium. E10.5 embryos (a,c) and hearts (b,d) resulting from a cross of either Wnt1\u2013cre (a,b) or Tek\u2013cre (c,e) mice to the Z/EG reporter mouse. Cre activates expression of GFP in derivatives of the neural crest (a,b) and of endothelial cells (c\u2013e). A transverse section through the heart of a Tek\u2013cre \u00d7 Z/EG embryo (e) shows GFP expression in both endothelial cells lining the endocardial cushions (yellow arrows) and the endothelial-derived mesenchymal cells within the cushion (white arrows). f, PCR was used to detect the recombined allele (Rcre) as described previously7 in genomic DNAs isolated from Nf1flox embryonic hearts either positive or negative for Tek\u2013cre. PCR amplification of the Nf1flox allele from both samples is shown below as control. pa, pharyngeal arches; nt, neural tube; rv, right ventricle; lv, left ventricle; nc, neural crest; h, heart; ec, endocardial cushions.", "width": 630, "height": 828, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76], "b": [17, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76], "c": [17, 18, 19, 20, 21, 22, 23, 31, 32, 33, 34, 35, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 78, 79, 80, 81, 82, 83, 84, 85, 86], "d": [25, 26, 27, 28, 29, 61, 62, 63, 64, 65, 66, 67, 78, 79, 80, 81, 82, 83, 84, 85, 86], "e": [128, 129, 130, 131, 132, 133, 134, 135, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 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{"pdf_hash": "565a15c194a7d8487484cff6f5b327208f3aa03f", "fig_key": "Figure8", "fig_uri": "14-Figure8-1.png", "text": "FIGURE 8 | Marf regulates ER stress in frataxin deficient glial cells. (A) Representative image of 35-day-old frataxin-deficient GGCs coexpressing a control construct (fhRNAi-1/+; Repo-GAL4/ UAS-mcherryRNAi) stained with anti-BiP. A second UAS line does not influence BiP induction in frataxin-deficient flies. (B) Representative image of 35-day-old frataxin-deficient GGCs coexpressing a MarfRNAi construct (fhRNAi-1/+; Repo-GAL4/ UAS-MarfRNAi) stained with anti-BiP. Clear suppression of BiP induction by Marf silencing. (C) Representative image of 35-day-old control GGCs (Repo-GAL4/ UAS-MarfRNAi) stained with anti-BiP. In contrast to muscles (Debattisti et al., 2014), Marf downregulation in glia did not induce BiP expression. (D) Representative image of 35-day-old frataxin-deficient GGCs coexpressing Marf downregulation and the Xbp1GFP reporter (fhRNAi-1/UAS-Xbp1GFP; Repo-GAL4/ UAS-MarfRNAi) stained with anti-BiP. Nuclear localization of Xbp1 and BiP expression were restored to wild type levels. (E) A second RNAi line to downregulate Marf expression also reduces BiP immunoreactivity in FRDA flies (fhRNAi-1/+; Repo-GAL4/UAS-MarfRNAi(TRiP)). 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{"pdf_hash": "01577f988fbb52077c51b8ee672fa8aa13d5a5a8", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 I. Photographs of serially adjacent sections processed for corticostriatal labeling (dark-field photographs; A, B) and for enkephalinlike immunoreactivity (reverse-contrast photographs; A', B') demonstrating the relationship between corticostriatal projection fibers and striosomes. In monkey M2 (A, A '), sections at approximately A 16 show that projection fibers labeled by an injection of WGA-HRP in the FEF crisply avoid striosomes (see Fig. 5 for injection site). In monkey M7 (B, B ), sections at approximately A 15 (Macucu mulattu) show that the SMA fibers (WGA-HRP) crisply avoid striosomes in the putamen; where striatal labeling is heaviest in the caudate nucleus, striosomal avoids are less obvious (injection site indicated on the brain hemisphere shown here). Asterisks indicate the locations of corresponding striosomes on the pairs of sections. AC, anterior commissure; CN, caudate nucleus; GPe, globus pallidus external segment; P, putamen; T/z, thalamus. 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{"pdf_hash": "558966f86704b4f838103e7298c60e9ad99a87b6", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3 Anterior Segment Optical Coherence Tomography (AS-OCT) images of a corneal sample obtained during tissue storage. The corneal central thickness was 670 mm before dissection (A). The posterior lenticule central corneal thickness was 240 mm immediately after dissection (B); 250 microns at 4 h (C); 230 mm at 24 h (D) and 220 mm at 48 h post-cut (E). 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{"pdf_hash": "cff9ec2b69c9b82504a04e5ecc9f71b5fd124c80", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. (A) Photograph of dissected section compared with 2D PD TSE transverse MR slice, and (B) 2D T2-weighted TSE fat saturated sagittal MR image of a L1L2 IVD. The anterior lamellae are drawn into the annular fissure (indicated by the arrow) in the sagittal plane (right anterio-lateral in the transverse plane). The fibrotic nucleus appears less intense, and fissures in the nucleus closer to the endplates appear bright. The vertebral-fluid rearrangement due to repeated freeze-thaw cycles are seen as a linear pattern of hyperintense signals within the vertebral bodies on the sagittal image. 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{"pdf_hash": "14820a6ccc2e1951a0014dcad48f320d2d24f6c1", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Alterations in mucus plugging on high resolution computed tomography imaging of the chest comparing images at baseline and then one year after ivacaftor therapy.", "width": 882, "height": 492, "subcaptions": {"a": [20], "b": [21, 22, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "805a26fd-1f1f-4927-b93a-e212ef0bf14e", "label": "a", "points": [[2.1, 2.3], [2.1, 484.5], [446.6, 484.5], [446.6, 2.3]], "color": "yellow"}, {"id": "e3a45403-6022-4c48-beba-3741fc4027d4", "label": "b", "points": [[459.1, 2.3], [459.1, 487.2], [877.2, 487.2], [877.2, 2.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Alterations", "start": 8, "end": 19, "id": 4}, {"text": "in", "start": 20, "end": 22, "id": 5}, {"text": "mucus", "start": 23, "end": 28, "id": 6}, {"text": "plugging", "start": 29, "end": 37, "id": 7}, {"text": "on", "start": 38, "end": 40, "id": 8}, {"text": "high", "start": 41, "end": 45, "id": 9}, {"text": "resolution", "start": 46, "end": 56, "id": 10}, {"text": "computed", "start": 57, "end": 65, "id": 11}, {"text": "tomography", "start": 66, "end": 76, "id": 12}, {"text": "imaging", "start": 77, "end": 84, "id": 13}, {"text": "of", "start": 85, "end": 87, "id": 14}, {"text": "the", "start": 88, "end": 91, "id": 15}, {"text": "chest", "start": 92, "end": 97, "id": 16}, {"text": "comparing", "start": 98, "end": 107, "id": 17}, {"text": "images", "start": 108, "end": 114, "id": 18}, {"text": "at", "start": 115, "end": 117, "id": 19}, {"text": "baseline", "start": 118, "end": 126, "id": 20}, {"text": "and", "start": 127, "end": 130, "id": 21}, {"text": "then", "start": 131, "end": 135, "id": 22}, {"text": "one", "start": 136, "end": 139, "id": 23}, {"text": "year", "start": 140, "end": 144, "id": 24}, {"text": "after", "start": 145, "end": 150, "id": 25}, {"text": "ivacaftor", "start": 151, "end": 160, "id": 26}, {"text": "therapy", "start": 161, "end": 168, "id": 27}, {"text": ".", "start": 168, "end": 169, "id": 28}]}
{"pdf_hash": "bc4eec87f6e0e14da1282335bfbcee50718db247", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 PET/CT images illustrating tumor volume delineation of a typical gastric cancer. a, transverse PET image; b, transverse PET/CT fusion image; c, maximum intensity projection image. Circles in a and b denote volume of interest under a threshold of SUV \u2265 2.5. In addition, multiple metastases can be visualized in the liver (arrows). 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{"pdf_hash": "8e94bc9b0e9b113d1175e3a1f34b00f3addedcd8", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 a Color fundus photograph of the left eye on presentation. b Optical coherence tomography through the lesion showing the choroidal neovascular membrane, retinal thickening, and subretinal fluid", "width": 652, "height": 774, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13], "b": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32]}, "subfigures": [{"id": "8590a358-07fc-4e92-b086-b0f81395f883", "label": "a", "points": [[33.1, 21.6], [33.1, 477.9], [622.3, 477.9], [622.3, 21.6]], "color": "yellow"}, {"id": "938b35a3-f74d-4ae7-ad52-0f5e2b2a88a3", "label": "b", "points": [[30, 478.3], [30, 742], [627.5, 742], [627.5, 478.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Color", "start": 9, "end": 14, "id": 4}, {"text": "fundus", "start": 15, "end": 21, "id": 5}, {"text": "photograph", "start": 22, "end": 32, "id": 6}, {"text": "of", "start": 33, "end": 35, "id": 7}, {"text": "the", "start": 36, "end": 39, "id": 8}, {"text": "left", "start": 40, "end": 44, "id": 9}, {"text": "eye", "start": 45, "end": 48, "id": 10}, {"text": "on", "start": 49, "end": 51, "id": 11}, {"text": "presentation", "start": 52, "end": 64, "id": 12}, {"text": ".", "start": 64, "end": 65, "id": 13}, {"text": "b", "start": 66, "end": 67, "id": 14}, {"text": "Optical", "start": 68, "end": 75, "id": 15}, {"text": "coherence", "start": 76, "end": 85, "id": 16}, {"text": "tomography", "start": 86, "end": 96, "id": 17}, {"text": "through", "start": 97, "end": 104, "id": 18}, {"text": "the", "start": 105, "end": 108, "id": 19}, {"text": "lesion", "start": 109, "end": 115, "id": 20}, {"text": "showing", "start": 116, "end": 123, "id": 21}, {"text": "the", "start": 124, "end": 127, "id": 22}, {"text": "choroidal", "start": 128, "end": 137, "id": 23}, {"text": "neovascular", "start": 138, "end": 149, "id": 24}, {"text": "membrane", "start": 150, "end": 158, "id": 25}, {"text": ",", "start": 158, "end": 159, "id": 26}, {"text": "retinal", "start": 160, "end": 167, "id": 27}, {"text": "thickening", "start": 168, "end": 178, "id": 28}, {"text": ",", "start": 178, "end": 179, "id": 29}, {"text": "and", "start": 180, "end": 183, "id": 30}, {"text": "subretinal", "start": 184, "end": 194, "id": 31}, {"text": "fluid", "start": 195, "end": 200, "id": 32}]}
{"pdf_hash": "f12813383b32de7b39d1e7f1fca7203518126104", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIG. 1. A, Brain CT scan acquired on admission. Mild atrophy of the bilateral nucleus caudatus and corpus striatum is shown relative to normal features for patient\u2019s age. B, T1-weighted brain MRI acquired on d 17 after admission. Axial image of brain MRI shows atrophy of the striatum and enlargement of the frontal horns.", "width": 668, "height": 374, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "3ca813eb-45f3-41ad-936b-9947f70bf2a1", "label": "a", "points": [[1.6, 4.2], [1.6, 343], [328.7, 343], [328.7, 4.2]], "color": "yellow"}, {"id": "222fd9b1-dae9-48cc-bffe-e5daf61f8963", "label": "b", "points": [[334, 4.2], [334, 341.9], [666.4, 341.9], [666.4, 4.2]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": ",", "start": 9, "end": 10, "id": 5}, {"text": "Brain", "start": 11, "end": 16, "id": 6}, {"text": "CT", "start": 17, "end": 19, "id": 7}, {"text": "scan", "start": 20, "end": 24, "id": 8}, {"text": "acquired", "start": 25, "end": 33, "id": 9}, {"text": "on", "start": 34, "end": 36, "id": 10}, {"text": "admission", "start": 37, "end": 46, "id": 11}, {"text": ".", "start": 46, "end": 47, "id": 12}, {"text": "Mild", "start": 48, "end": 52, "id": 13}, {"text": "atrophy", "start": 53, "end": 60, "id": 14}, {"text": "of", "start": 61, "end": 63, "id": 15}, {"text": "the", "start": 64, "end": 67, "id": 16}, {"text": "bilateral", "start": 68, "end": 77, "id": 17}, {"text": "nucleus", "start": 78, "end": 85, "id": 18}, {"text": "caudatus", "start": 86, "end": 94, "id": 19}, {"text": "and", "start": 95, "end": 98, "id": 20}, {"text": "corpus", "start": 99, "end": 105, "id": 21}, {"text": "striatum", "start": 106, "end": 114, "id": 22}, {"text": "is", "start": 115, "end": 117, "id": 23}, {"text": "shown", "start": 118, "end": 123, "id": 24}, {"text": "relative", "start": 124, "end": 132, "id": 25}, {"text": "to", "start": 133, "end": 135, "id": 26}, {"text": "normal", "start": 136, "end": 142, "id": 27}, {"text": "features", "start": 143, "end": 151, "id": 28}, {"text": "for", "start": 152, "end": 155, "id": 29}, {"text": "patient", "start": 156, "end": 163, "id": 30}, {"text": "\u2019s", "start": 163, "end": 165, "id": 31}, {"text": "age", "start": 166, "end": 169, "id": 32}, {"text": ".", "start": 169, "end": 170, "id": 33}, {"text": "B", "start": 171, "end": 172, "id": 34}, {"text": ",", "start": 172, "end": 173, "id": 35}, {"text": "T1-weighted", "start": 174, "end": 185, "id": 36}, {"text": "brain", "start": 186, "end": 191, "id": 37}, {"text": "MRI", "start": 192, "end": 195, "id": 38}, {"text": "acquired", "start": 196, "end": 204, "id": 39}, {"text": "on", "start": 205, "end": 207, "id": 40}, {"text": "d", "start": 208, "end": 209, "id": 41}, {"text": "17", "start": 210, "end": 212, "id": 42}, {"text": "after", "start": 213, "end": 218, "id": 43}, {"text": "admission", "start": 219, "end": 228, "id": 44}, {"text": ".", "start": 228, "end": 229, "id": 45}, {"text": "Axial", "start": 230, "end": 235, "id": 46}, {"text": "image", "start": 236, "end": 241, "id": 47}, {"text": "of", "start": 242, "end": 244, "id": 48}, {"text": "brain", "start": 245, "end": 250, "id": 49}, {"text": "MRI", "start": 251, "end": 254, "id": 50}, {"text": "shows", "start": 255, "end": 260, "id": 51}, {"text": "atrophy", "start": 261, "end": 268, "id": 52}, {"text": "of", "start": 269, "end": 271, "id": 53}, {"text": "the", "start": 272, "end": 275, "id": 54}, {"text": "striatum", "start": 276, "end": 284, "id": 55}, {"text": "and", "start": 285, "end": 288, "id": 56}, {"text": "enlargement", "start": 289, "end": 300, "id": 57}, {"text": "of", "start": 301, "end": 303, "id": 58}, {"text": "the", "start": 304, "end": 307, "id": 59}, {"text": "frontal", "start": 308, "end": 315, "id": 60}, {"text": "horns", "start": 316, "end": 321, "id": 61}, {"text": ".", "start": 321, "end": 322, "id": 62}]}
{"pdf_hash": "5eb5ae6d0a17f723873c981277610f9fe98a2aa8", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig 3. Sagittal images showing disk displacement without reduction to condyle. A, Closed mouth; B, open mouth. Disk (arrow) was anteriorly displaced relative to posterior slope of articular eminence (E) and head of condyle (C), but without reduction of disk on mouth opening.", "width": 864, "height": 420, "subcaptions": {"a": [13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22]}, "subfigures": [{"id": "33ab9e13-1666-4cb6-b647-ebb79cab84c7", "label": "a", "points": [[0.7, 2.7], [0.7, 416.3], [423.8, 416.3], [423.8, 2.7]], "color": "yellow"}, {"id": "f78b5184-5a16-4607-9188-4d04d3811650", "label": "b", "points": [[449.8, 1.4], [449.8, 416.3], [860.6, 416.3], [860.6, 1.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "3", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Sagittal", "start": 7, "end": 15, "id": 3}, {"text": "images", "start": 16, "end": 22, "id": 4}, {"text": "showing", "start": 23, "end": 30, "id": 5}, {"text": "disk", "start": 31, "end": 35, "id": 6}, {"text": "displacement", "start": 36, "end": 48, "id": 7}, {"text": "without", "start": 49, "end": 56, "id": 8}, {"text": "reduction", "start": 57, "end": 66, "id": 9}, {"text": "to", "start": 67, "end": 69, "id": 10}, {"text": "condyle", "start": 70, "end": 77, "id": 11}, {"text": ".", "start": 77, "end": 78, "id": 12}, {"text": "A", "start": 79, "end": 80, "id": 13}, {"text": ",", "start": 80, "end": 81, "id": 14}, {"text": "Closed", "start": 82, "end": 88, "id": 15}, {"text": "mouth", "start": 89, "end": 94, "id": 16}, {"text": ";", "start": 94, "end": 95, "id": 17}, {"text": "B", "start": 96, "end": 97, "id": 18}, {"text": ",", "start": 97, "end": 98, "id": 19}, {"text": "open", "start": 99, "end": 103, "id": 20}, {"text": "mouth", "start": 104, "end": 109, "id": 21}, {"text": ".", "start": 109, "end": 110, "id": 22}, {"text": "Disk", "start": 111, "end": 115, "id": 23}, {"text": "(", "start": 116, "end": 117, "id": 24}, {"text": "arrow", "start": 117, "end": 122, "id": 25}, {"text": ")", "start": 122, "end": 123, "id": 26}, {"text": "was", "start": 124, "end": 127, "id": 27}, {"text": "anteriorly", "start": 128, "end": 138, "id": 28}, {"text": "displaced", "start": 139, "end": 148, "id": 29}, {"text": "relative", "start": 149, "end": 157, "id": 30}, {"text": "to", "start": 158, "end": 160, "id": 31}, {"text": "posterior", "start": 161, "end": 170, "id": 32}, {"text": "slope", "start": 171, "end": 176, "id": 33}, {"text": "of", "start": 177, "end": 179, "id": 34}, {"text": "articular", "start": 180, "end": 189, "id": 35}, {"text": "eminence", "start": 190, "end": 198, "id": 36}, {"text": "(", "start": 199, "end": 200, "id": 37}, {"text": "E", "start": 200, "end": 201, "id": 38}, {"text": ")", "start": 201, "end": 202, "id": 39}, {"text": "and", "start": 203, "end": 206, "id": 40}, {"text": "head", "start": 207, "end": 211, "id": 41}, {"text": "of", "start": 212, "end": 214, "id": 42}, {"text": "condyle", "start": 215, "end": 222, "id": 43}, {"text": "(", "start": 223, "end": 224, "id": 44}, {"text": "C", "start": 224, "end": 225, "id": 45}, {"text": ")", "start": 225, "end": 226, "id": 46}, {"text": ",", "start": 226, "end": 227, "id": 47}, {"text": "but", "start": 228, "end": 231, "id": 48}, {"text": "without", "start": 232, "end": 239, "id": 49}, {"text": "reduction", "start": 240, "end": 249, "id": 50}, {"text": "of", "start": 250, "end": 252, "id": 51}, {"text": "disk", "start": 253, "end": 257, "id": 52}, {"text": "on", "start": 258, "end": 260, "id": 53}, {"text": "mouth", "start": 261, "end": 266, "id": 54}, {"text": "opening", "start": 267, "end": 274, "id": 55}, {"text": ".", "start": 274, "end": 275, "id": 56}]}
{"pdf_hash": "1995627de75ab3c56c62f24577529e92b0290881", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 BMP-4-implanted bead locally induces PCD in the NT. BMP-4 or PBS (control) soaked beads (50-100 mm in size) were implanted in the NT at the level of somite four to five of eight to nine somite embryos in ovo and incubated at 381C for 6 h. Embryos that developed into 12 to 14 somites were taken for analysis. PCD was assessed qualitatively by neutral red staining in micrographs in (a) and (b) shows the difference in the pattern of neutral red staining around the implanted BMP-4 (a) and control (b) beads. (c) and (d) shows a confocal micrograph of the dorsal localization of BMP-4 bead induced PCD in an NT transverse section taken near the BMP-4 bead, which was double labeled by immunofluorescence with CM1 antibodies that detect caspase-3-like activity in the cytoplasm of the apoptotic cells (green) and by PI (red) that stains all nuclei to assess for pyknosis of apoptotic cells. (d) is two times confocal magnification of C ( \u00c2 40 objective); arrows indicate two examples of double-labeled apoptotic cells in the dorsal NT in detail. e: ectoderm; n: notochord; nt: neural tube; s: somite. 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{"pdf_hash": "da40b9d1228fd8d7b295141373ca1e3819e68bc3", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 a Transaxial view from the CT pulmonary angiogram shows compression of the right pulmonary artery and b another transaxial view shows compression of the mainstem bronchi. c A sagittal view shows compression of both the right pulmonary artery and right mainstem bronchus", "width": 1374, "height": 350, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 30, 31]}, "subfigures": [{"id": "b1453af2-359b-4ac3-873b-4a980b2ceb28", "label": "a", "points": [[11.2, 22.4], [11.2, 341.5], [467.1, 341.5], [467.1, 22.4]], "color": "yellow"}, {"id": "40e3bab9-4212-4bb4-ad3a-ece65b9e6f3d", "label": "b", "points": [[486.6, 22.4], [486.6, 348.1], [920.8, 348.1], [920.8, 22.4]], "color": "cyan"}, {"id": "cf129dfd-cce6-4fb6-a342-8f65054ffc21", "label": "c", "points": [[962, 26.8], [962, 343.7], [1370.2, 343.7], [1370.2, 26.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Transaxial", "start": 9, "end": 19, "id": 4}, {"text": "view", "start": 20, "end": 24, "id": 5}, {"text": "from", "start": 25, "end": 29, "id": 6}, {"text": "the", "start": 30, "end": 33, "id": 7}, {"text": "CT", "start": 34, "end": 36, "id": 8}, {"text": "pulmonary", "start": 37, "end": 46, "id": 9}, {"text": "angiogram", "start": 47, "end": 56, "id": 10}, {"text": "shows", "start": 57, "end": 62, "id": 11}, {"text": "compression", "start": 63, "end": 74, "id": 12}, {"text": "of", "start": 75, "end": 77, "id": 13}, {"text": "the", "start": 78, "end": 81, "id": 14}, {"text": "right", "start": 82, "end": 87, "id": 15}, {"text": "pulmonary", "start": 88, "end": 97, "id": 16}, {"text": "artery", "start": 98, "end": 104, "id": 17}, {"text": "and", "start": 105, "end": 108, "id": 18}, {"text": "b", "start": 109, "end": 110, "id": 19}, {"text": "another", "start": 111, "end": 118, "id": 20}, {"text": "transaxial", "start": 119, "end": 129, "id": 21}, {"text": "view", "start": 130, "end": 134, "id": 22}, {"text": "shows", "start": 135, "end": 140, "id": 23}, {"text": "compression", "start": 141, "end": 152, "id": 24}, {"text": "of", "start": 153, "end": 155, "id": 25}, {"text": "the", "start": 156, "end": 159, "id": 26}, {"text": "mainstem", "start": 160, "end": 168, "id": 27}, {"text": "bronchi", "start": 169, "end": 176, "id": 28}, {"text": ".", "start": 176, "end": 177, "id": 29}, {"text": "c", "start": 178, "end": 179, "id": 30}, {"text": "A", "start": 180, "end": 181, "id": 31}, {"text": "sagittal", "start": 182, "end": 190, "id": 32}, {"text": "view", "start": 191, "end": 195, "id": 33}, {"text": "shows", "start": 196, "end": 201, "id": 34}, {"text": "compression", "start": 202, "end": 213, "id": 35}, {"text": "of", "start": 214, "end": 216, "id": 36}, {"text": "both", "start": 217, "end": 221, "id": 37}, {"text": "the", "start": 222, "end": 225, "id": 38}, {"text": "right", "start": 226, "end": 231, "id": 39}, {"text": "pulmonary", "start": 232, "end": 241, "id": 40}, {"text": "artery", "start": 242, "end": 248, "id": 41}, {"text": "and", "start": 249, "end": 252, "id": 42}, {"text": "right", "start": 253, "end": 258, "id": 43}, {"text": "mainstem", "start": 259, "end": 267, "id": 44}, {"text": "bronchus", "start": 268, "end": 276, "id": 45}]}
{"pdf_hash": "23b366ef9d2fdaaa1c34284393b369320c220ff5", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Figure 5 CT scan of the right scapula with (A) axial soft tissue, (B) axial and (C) sagittal bone windows, reveals a large destructive mass lesion involving the posterior upper body of the scapula (arrows, A,B) and acromion (white arrow, C) with an associated large extraosseous soft tissue component. (D) Axial fused PET/CT image of the right scapula reveals intense FDG uptake (SUV max 20) within the destructive scapular mass and extraosseous soft tissue component.", "width": 1266, "height": 952, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "b": [2, 3, 4, 5, 6, 7, 8, 16, 17, 18, 19, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48], "c": [2, 3, 4, 5, 6, 7, 8, 21, 22, 23, 24, 25, 26, 27, 28, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65], "d": [66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98]}, "subfigures": [{"id": "286b998c-8788-43c8-b5c8-bf3fba8e432a", "label": "a", "points": [[39, 34], [39, 476], [619, 476], [619, 34]], "color": "yellow"}, {"id": "4bed0d59-39de-4c2a-a2c8-2658ea4831e5", "label": "b", "points": [[649, 26], [649, 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{"pdf_hash": "6a0b7e3a7e3b00f32fc474f4c9466f38b4724073", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1. Representative responder vs non-responder. Representative DOS parametric maps for a responder (left column) and a non-responder (right column) are presented, and corresponding clinical contrast-enhanced magnetic resonance images of the breast. Baseline DOS images were acquired prior to starting NAC, using a tomographic diffuse optical spectroscopy device. Parametric maps were constructed volumetrically for analysis in order to calculate the GLCM texture features.", "width": 1224, "height": 1084, "subcaptions": {"a": [15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26, 27, 28, 29]}, "subfigures": [{"id": "f8e0fb34-f54d-40ed-8cc0-fd092abe0148", "label": "a", "points": [[69.2, -0.3], [69.2, 519.8], [583.5, 519.8], [583.5, -0.3]], "color": "yellow"}, {"id": "6bb674a7-197e-442f-824e-8c375748b76f", "label": "a", "points": [[65.3, 531.4], [65.3, 1051.5], [577.7, 1051.5], [577.7, 531.4]], "color": "cyan"}, {"id": "5066840b-b94b-44db-9a1e-6617b8bfe044", "label": "b", "points": [[1192.6, 519.8], [1192.6, -0.3], [662.8, -0.3], [662.8, 519.8]], "color": "magenta"}, {"id": "70b13892-fa0c-49b2-b3fb-434812779759", "label": "b", "points": [[664.7, 529.5], [664.7, 1049.6], [1194.5, 1049.6], [1194.5, 529.5]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", 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{"pdf_hash": "6770a172c2c2234dcb6709c61f76c650498002fb", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3 Two examples of abnormal a2 labeling patterns in dysgenic myotubes with poorly (a) and highly developed T-tubules (b) . Myotubes were double labeled for the DHP receptor a2 subunit (a and b) and Ttubules (a' and d) ; the corresponding phase contrast images are shown (a\" and b') . Immunolabel for the a2 Subunit did not occur in punctate patterns as observed in normal cultures. Instead, a2 was frequently colocalized with Ttubule specific antigens in structures preferentially located in the perinuclear region (a; arrows) while normal, randomly oriented Ttubules (upper portion of the myotube) were devoid of a2 label . Little or no a2 was expressed in the myotube shown in b, however, the Ttubules achieved the highest degree of organization reached in culture, as indicated by their transverse orientation at the I-A interfaces (arrowheads) . Bars, 10 Am .", "width": 1366, "height": 840, "subcaptions": null, "subfigures": [{"id": "ba01e143-4bd5-49ca-aafb-0667550216a4", "label": "a", "points": [[4.3, 8.6], [4.3, 274.1], [662.5, 274.1], [662.5, 8.6]], "color": "yellow"}, {"id": "7238d5ce-7f40-4fdc-b3eb-c5fcb26bcbd8", "label": "b", "points": [[8.6, 295.6], [8.6, 550.3], [669, 550.3], [669, 295.6]], "color": "cyan"}, {"id": "125de1ff-9dcc-4536-8ead-148c76ddb21a", "label": "c", "points": [[662.5, 563.2], [662.5, 824.4], [2.2, 824.4], [2.2, 563.2]], "color": "magenta"}, {"id": "1346163c-b1ed-4d14-9b82-08a2882a0ce0", "label": "d", "points": [[710, 274.1], [710, 12.9], [1348.7, 12.9], [1348.7, 274.1]], "color": "springgreen"}, {"id": "ab8e4198-e58c-404b-905b-4871c38c66f0", "label": "e", "points": [[1359.5, 289.2], [1359.5, 554.6], [703.5, 554.6], [703.5, 289.2]], "color": "tomato"}, {"id": "5eb0aabf-797d-474c-9c5f-3feeea1835dc", "label": "f", "points": [[705.7, 561.1], [705.7, 833], [1353.1, 833], [1353.1, 561.1]], "color": 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{"pdf_hash": "bc034e03ca6290fd8d62875101468a4512535149", "fig_key": "Figure7", "fig_uri": "4-Figure7-1.png", "text": "Fig. 7 Brain magnetic resonance imaging after the total removal of left-sided vestibular schwannoma. (A) T2-weighted image. (B) 3D SSFP AIC. (C) T1 \u00fe Gd.", "width": 626, "height": 608, "subcaptions": {"a": [18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30], "c": [31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "9c122337-d4d2-4d4c-8d2b-a8e83913054a", "label": "a", "points": [[2, 1.7], [2, 307.7], [311, 307.7], [311, 1.7]], "color": "yellow"}, {"id": "65368173-9266-432d-9c34-2e336b8c7da1", "label": "b", "points": [[313, 3.7], [313, 306.7], [624, 306.7], [624, 3.7]], "color": "cyan"}, {"id": "5b6a5b72-9506-43e8-bc0f-7e4be495ff4a", "label": "c", "points": [[4, 312.7], [4, 605.7], [624, 605.7], [624, 312.7]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "7", "start": 5, "end": 6, "id": 2}, {"text": "Brain", "start": 7, "end": 12, "id": 3}, {"text": "magnetic", "start": 13, "end": 21, "id": 4}, {"text": "resonance", "start": 22, "end": 31, "id": 5}, {"text": "imaging", "start": 32, "end": 39, "id": 6}, {"text": "after", "start": 40, "end": 45, "id": 7}, {"text": "the", "start": 46, "end": 49, "id": 8}, {"text": "total", "start": 50, "end": 55, "id": 9}, {"text": "removal", "start": 56, "end": 63, "id": 10}, {"text": "of", "start": 64, "end": 66, "id": 11}, {"text": "left", "start": 67, "end": 71, "id": 12}, {"text": "-", "start": 71, "end": 72, "id": 13}, {"text": "sided", "start": 72, "end": 77, "id": 14}, {"text": "vestibular", "start": 78, "end": 88, "id": 15}, {"text": "schwannoma", "start": 89, "end": 99, "id": 16}, {"text": ".", "start": 99, "end": 100, "id": 17}, {"text": "(", "start": 101, "end": 102, "id": 18}, {"text": "A", "start": 102, "end": 103, "id": 19}, {"text": ")", "start": 103, "end": 104, "id": 20}, {"text": "T2-weighted", "start": 105, "end": 116, "id": 21}, {"text": "image", "start": 117, "end": 122, "id": 22}, {"text": ".", "start": 122, "end": 123, "id": 23}, {"text": "(", "start": 124, "end": 125, "id": 24}, {"text": "B", "start": 125, "end": 126, "id": 25}, {"text": ")", "start": 126, "end": 127, "id": 26}, {"text": "3D", "start": 128, "end": 130, "id": 27}, {"text": "SSFP", "start": 131, "end": 135, "id": 28}, {"text": "AIC", "start": 136, "end": 139, "id": 29}, {"text": ".", "start": 139, "end": 140, "id": 30}, {"text": "(", "start": 141, "end": 142, "id": 31}, {"text": "C", "start": 142, "end": 143, "id": 32}, {"text": ")", "start": 143, "end": 144, "id": 33}, {"text": "T1", "start": 145, "end": 147, "id": 34}, {"text": "\u00fe", "start": 148, "end": 149, "id": 35}, {"text": "Gd", "start": 150, "end": 152, "id": 36}, {"text": ".", "start": 152, "end": 153, "id": 37}]}
{"pdf_hash": "1d68eccd109dbece6244e0a59fbd29fe627ddbfa", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. (A) Clinical image of case 4. A large mass located in the right section of the back. (B) Computed tomography image demonstrating the lesion mostly localized in the back muscle, partly penetrating into the thorax.", "width": 1008, "height": 514, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "fff24997-c37f-418a-9370-a7ae87460ec7", "label": "a", "points": [[14.6, 3.7], [14.6, 511.7], [314, 511.7], [314, 3.7]], "color": "yellow"}, {"id": "feeffb3a-4b68-462d-948b-82ae089fb657", "label": "b", "points": [[422.3, 2.1], [422.3, 506.9], [1005.1, 506.9], [1005.1, 2.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Clinical", "start": 14, "end": 22, "id": 6}, {"text": "image", "start": 23, "end": 28, "id": 7}, {"text": "of", "start": 29, "end": 31, "id": 8}, {"text": "case", "start": 32, "end": 36, "id": 9}, {"text": "4", "start": 37, "end": 38, "id": 10}, {"text": ".", "start": 38, "end": 39, "id": 11}, {"text": "A", "start": 40, "end": 41, "id": 12}, {"text": "large", "start": 42, "end": 47, "id": 13}, {"text": "mass", "start": 48, "end": 52, "id": 14}, {"text": "located", "start": 53, "end": 60, "id": 15}, {"text": "in", "start": 61, "end": 63, "id": 16}, {"text": "the", "start": 64, "end": 67, "id": 17}, {"text": "right", "start": 68, "end": 73, "id": 18}, {"text": "section", "start": 74, "end": 81, "id": 19}, {"text": "of", "start": 82, "end": 84, "id": 20}, {"text": "the", "start": 85, "end": 88, "id": 21}, {"text": "back", "start": 89, "end": 93, "id": 22}, {"text": ".", "start": 93, "end": 94, "id": 23}, {"text": "(", "start": 95, "end": 96, "id": 24}, {"text": "B", "start": 96, "end": 97, "id": 25}, {"text": ")", "start": 97, "end": 98, "id": 26}, {"text": "Computed", "start": 99, "end": 107, "id": 27}, {"text": "tomography", "start": 108, "end": 118, "id": 28}, {"text": "image", "start": 119, "end": 124, "id": 29}, {"text": "demonstrating", "start": 125, "end": 138, "id": 30}, {"text": "the", "start": 139, "end": 142, "id": 31}, {"text": "lesion", "start": 143, "end": 149, "id": 32}, {"text": "mostly", "start": 150, "end": 156, "id": 33}, {"text": "localized", "start": 157, "end": 166, "id": 34}, {"text": "in", "start": 167, "end": 169, "id": 35}, {"text": "the", "start": 170, "end": 173, "id": 36}, {"text": "back", "start": 174, "end": 178, "id": 37}, {"text": "muscle", "start": 179, "end": 185, "id": 38}, {"text": ",", "start": 185, "end": 186, "id": 39}, {"text": "partly", "start": 187, "end": 193, "id": 40}, {"text": "penetrating", "start": 194, "end": 205, "id": 41}, {"text": "into", "start": 206, "end": 210, "id": 42}, {"text": "the", "start": 211, "end": 214, "id": 43}, {"text": "thorax", "start": 215, "end": 221, "id": 44}, {"text": ".", "start": 221, "end": 222, "id": 45}]}
{"pdf_hash": "29f96ba1b7610c40388bc010291a1d77ddc55ee0", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 (a) Transverse section of sperm tails of the SEIBERSDORF strain of C. capitata within a single cyst. Each sperm is identical in showing a single axoneme (ax) and two paracrystalline bodies (pcb). (b) Transverse section of sperm tails of the MP strain of C. capitata within a single cyst. Some sperms show abnormal numbers of axonemes and/or PCB (four examples are circled), and the number of sperms is depleted below the normal range of 233\u2013256 per cyst.", "width": 912, "height": 532, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "b": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "70763c2e-2235-44cf-ba14-4b7b12c1f292", "label": "a", "points": [[1.3, 7.3], [1.3, 501.5], [434.9, 501.5], [434.9, 7.3]], "color": "yellow"}, {"id": "62306e57-427c-425b-9279-635c23b02aee", "label": "b", "points": [[462.3, 4.4], [462.3, 504.4], [898.9, 504.4], [898.9, 4.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", 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{"pdf_hash": "06573d6a9071194458a5c05b5584f9e58ba9684e", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. A, Squamous cell carcinoma invading the middle cranial fossa before chemoradiation. B, After chemoradiation. C, After craniofacial resection using a transcranial approach only, coronal view. No facial incisions were necessary. D, After craniofacial resection, sagittal view.", "width": 1332, "height": 1084, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15], "b": [16, 17, 18, 19, 20], "c": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "d": [41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "826f86c6-2392-4e77-90d9-4ee0578ad8c2", "label": "a", "points": [[4.2, 6.3], [4.2, 515.5], [654.4, 515.5], [654.4, 6.3]], "color": "yellow"}, {"id": "12fcc984-0309-44e5-be68-dc5c6370a9cd", "label": "b", "points": [[667.1, 513.4], [667.1, 6.3], [1325.7, 6.3], [1325.7, 513.4]], "color": "cyan"}, {"id": "fb6576a2-677f-4f14-af0c-320ec729194c", "label": "c", "points": [[656.5, 1060.6], [656.5, 521.9], [4.2, 521.9], [4.2, 1060.6]], "color": "magenta"}, {"id": "f80a8a2a-b94a-4b97-96a8-a76a16198f4c", "label": "d", "points": [[669.2, 1066.9], [669.2, 524], [1325.7, 524], [1325.7, 1066.9]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "Squamous", "start": 13, "end": 21, "id": 5}, {"text": "cell", "start": 22, "end": 26, "id": 6}, {"text": "carcinoma", "start": 27, "end": 36, "id": 7}, {"text": "invading", "start": 37, "end": 45, "id": 8}, {"text": "the", "start": 46, "end": 49, "id": 9}, {"text": "middle", "start": 50, "end": 56, "id": 10}, {"text": "cranial", "start": 57, "end": 64, "id": 11}, {"text": "fossa", "start": 65, "end": 70, "id": 12}, {"text": "before", "start": 71, "end": 77, "id": 13}, {"text": "chemoradiation", "start": 78, "end": 92, "id": 14}, {"text": ".", "start": 92, "end": 93, "id": 15}, {"text": "B", "start": 94, "end": 95, "id": 16}, {"text": ",", "start": 95, "end": 96, "id": 17}, {"text": "After", "start": 97, "end": 102, "id": 18}, {"text": "chemoradiation", "start": 103, "end": 117, "id": 19}, {"text": ".", "start": 117, "end": 118, "id": 20}, {"text": "C", "start": 119, "end": 120, "id": 21}, {"text": ",", "start": 120, "end": 121, "id": 22}, {"text": "After", "start": 122, "end": 127, "id": 23}, {"text": "craniofacial", "start": 128, "end": 140, "id": 24}, {"text": "resection", "start": 141, "end": 150, "id": 25}, {"text": "using", "start": 151, "end": 156, "id": 26}, {"text": "a", "start": 157, "end": 158, "id": 27}, {"text": "transcranial", "start": 159, "end": 171, "id": 28}, {"text": "approach", "start": 172, "end": 180, "id": 29}, {"text": "only", "start": 181, "end": 185, "id": 30}, {"text": ",", "start": 185, "end": 186, "id": 31}, {"text": "coronal", "start": 187, "end": 194, "id": 32}, {"text": "view", "start": 195, "end": 199, "id": 33}, {"text": ".", "start": 199, "end": 200, "id": 34}, {"text": "No", "start": 201, "end": 203, "id": 35}, {"text": "facial", "start": 204, "end": 210, "id": 36}, {"text": "incisions", "start": 211, "end": 220, "id": 37}, {"text": "were", "start": 221, "end": 225, "id": 38}, {"text": "necessary", "start": 226, "end": 235, "id": 39}, {"text": ".", "start": 235, "end": 236, "id": 40}, {"text": "D", "start": 237, "end": 238, "id": 41}, {"text": ",", "start": 238, "end": 239, "id": 42}, {"text": "After", "start": 240, "end": 245, "id": 43}, {"text": "craniofacial", "start": 246, "end": 258, "id": 44}, {"text": "resection", "start": 259, "end": 268, "id": 45}, {"text": ",", "start": 268, "end": 269, "id": 46}, {"text": "sagittal", "start": 270, "end": 278, "id": 47}, {"text": "view", "start": 279, "end": 283, "id": 48}, {"text": ".", "start": 283, "end": 284, "id": 49}]}
{"pdf_hash": "61bdd5df026528cd1f032e23cf215a4f652953e6", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. Spinal cord fibre Tracking (A): Whole cervical spinal cord fiber tracking reconstruction; the arrow indicates the laminectomy and implant site. (B) Magnetic resonance imaging (MRI) 15 days after stem cell graft. Directional color-coded fractional anisotropy map at the implant site level, obtained from diffusion tensor imaging acquisition, with evidence of apparent diffusion coefficient map. 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{"pdf_hash": "0c2e7c8ea85c9efc58ff65f30a0965312a384163", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. (A and B) Chest radiography and the CT scan showed a decrease in the size of the primary tumor. (C and D) Metastatic cutaneous lesions (arms, neck, and lip), cervical lymph nodes, and multiple nodules in the chest wall spontaneously regressed.", "width": 858, "height": 650, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "c": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "d": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "2cbb3255-1e20-4e69-b504-6fbf1558c04e", "label": "a", "points": [[1.6, 0.5], [1.6, 328.5], [421.8, 328.5], [421.8, 0.5]], "color": "yellow"}, {"id": "d7cbc689-007e-4710-b966-bd487d85c56c", "label": "b", "points": [[443.5, 1.8], [443.5, 316.3], [856.9, 316.3], [856.9, 1.8]], "color": "cyan"}, {"id": "a2b56183-0edb-43bd-9599-197f045c5687", "label": "c", "points": [[1.6, 336.6], [1.6, 648.4], [423.1, 648.4], [423.1, 336.6]], "color": "magenta"}, {"id": "c710db0e-ff51-4033-a3b7-cb1a616f1d68", "label": "d", "points": [[446.2, 330.7], [446.2, 643.8], [851.5, 643.8], [851.5, 330.7]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": "and", "start": 13, "end": 16, "id": 5}, {"text": "B", "start": 17, "end": 18, "id": 6}, {"text": ")", "start": 18, "end": 19, "id": 7}, {"text": "Chest", "start": 20, "end": 25, "id": 8}, {"text": "radiography", "start": 26, "end": 37, "id": 9}, {"text": "and", "start": 38, "end": 41, "id": 10}, {"text": "the", "start": 42, "end": 45, "id": 11}, {"text": "CT", "start": 46, "end": 48, "id": 12}, {"text": "scan", "start": 49, "end": 53, "id": 13}, {"text": "showed", "start": 54, "end": 60, "id": 14}, {"text": "a", "start": 61, "end": 62, "id": 15}, {"text": "decrease", "start": 63, "end": 71, "id": 16}, {"text": "in", "start": 72, "end": 74, "id": 17}, {"text": "the", "start": 75, "end": 78, "id": 18}, {"text": "size", "start": 79, "end": 83, "id": 19}, {"text": "of", "start": 84, "end": 86, "id": 20}, {"text": "the", "start": 87, "end": 90, "id": 21}, {"text": "primary", "start": 91, "end": 98, "id": 22}, {"text": "tumor", "start": 99, "end": 104, "id": 23}, {"text": ".", "start": 104, "end": 105, "id": 24}, {"text": "(", "start": 106, "end": 107, "id": 25}, {"text": "C", "start": 107, "end": 108, "id": 26}, {"text": "and", "start": 109, "end": 112, "id": 27}, {"text": "D", "start": 113, "end": 114, "id": 28}, {"text": ")", "start": 114, "end": 115, "id": 29}, {"text": "Metastatic", "start": 116, "end": 126, "id": 30}, {"text": "cutaneous", "start": 127, "end": 136, "id": 31}, {"text": "lesions", "start": 137, "end": 144, "id": 32}, {"text": "(", "start": 145, "end": 146, "id": 33}, {"text": "arms", "start": 146, "end": 150, "id": 34}, {"text": ",", "start": 150, "end": 151, "id": 35}, {"text": "neck", "start": 152, "end": 156, "id": 36}, {"text": ",", "start": 156, "end": 157, "id": 37}, {"text": "and", "start": 158, "end": 161, "id": 38}, {"text": "lip", "start": 162, "end": 165, "id": 39}, {"text": ")", "start": 165, "end": 166, "id": 40}, {"text": ",", "start": 166, "end": 167, "id": 41}, {"text": "cervical", "start": 168, "end": 176, "id": 42}, {"text": "lymph", "start": 177, "end": 182, "id": 43}, {"text": "nodes", "start": 183, "end": 188, "id": 44}, {"text": ",", "start": 188, "end": 189, "id": 45}, {"text": "and", "start": 190, "end": 193, "id": 46}, {"text": "multiple", "start": 194, "end": 202, "id": 47}, {"text": "nodules", "start": 203, "end": 210, "id": 48}, {"text": "in", "start": 211, "end": 213, "id": 49}, {"text": "the", "start": 214, "end": 217, "id": 50}, {"text": "chest", "start": 218, "end": 223, "id": 51}, {"text": "wall", "start": 224, "end": 228, "id": 52}, {"text": "spontaneously", "start": 229, "end": 242, "id": 53}, {"text": "regressed", "start": 243, "end": 252, "id": 54}, {"text": ".", "start": 252, "end": 253, "id": 55}]}
{"pdf_hash": "f326120f488a2bbaaf9fe88649279240ef731d04", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig 1. Nonfocal symptoms in MIS patients with or without MetS on brain MRI. A 65-year-old female with headache and dizziness for 3d (NIHSS = 0 score), several typical small infarcts in the right lateral temporal and parietal area is visible on the DWI (A, arrows), and she were diagnosed with MIS with MetS. A 52-year-old male with dizziness for 2 d (NIHSS = 0) and with MetS, on the FLAIR imaging shows two recent small infarcts near the centrum ovale areas (B, arrows). A 76-year-old male with recurrent headache for 10 d (NIHSS = 0) without MetS, MRI-FLAIR shows typical recent multiple small infarcts in bilateral anterior circulation areas (C, arrows). doi:10.1371/journal.pone.0156243.g001", "width": 1496, "height": 530, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102], "c": [104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142]}, "subfigures": [{"id": "81a002fd-6cc6-456c-8fd7-22653f81bfb7", "label": "a", "points": [[4.7, 7.1], [4.7, 498.7], [482.1, 498.7], [482.1, 7.1]], "color": "yellow"}, 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{"pdf_hash": "3aa7a066787ba41f93a0eb7bddb352337b894041", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Coronal views demonstrating increased dose to the brachial plexus (contoured in purple) from the intensitymodulated radiotherapy plan (a) compared with the conventional radiotherapy plan (b) for the patient from Figure 1. Isodose lines are 72 Gy (grey), 70 Gy (red), 66 Gy (khaki), 60 Gy (green), 56 Gy (light blue), and 30 Gy (purple).", "width": 1396, "height": 794, "subcaptions": {"a": [19, 20, 21, 22, 23, 24], "b": [32, 33, 28, 29, 30, 31]}, "subfigures": [{"id": "997bf896-72bf-4c2e-afc2-fceca5b777d5", "label": "a", "points": [[3.3, 99.2], [3.3, 769.7], [671.6, 769.7], [671.6, 99.2]], "color": "yellow"}, {"id": "c93b5a2f-8c42-4cad-ad51-c1b516c96ebf", "label": "b", "points": [[733.3, 4.4], [733.3, 769.7], [1392.7, 769.7], [1392.7, 4.4]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Coronal", "start": 10, "end": 17, "id": 3}, {"text": "views", "start": 18, "end": 23, "id": 4}, {"text": "demonstrating", "start": 24, "end": 37, "id": 5}, {"text": "increased", "start": 38, "end": 47, "id": 6}, {"text": "dose", "start": 48, "end": 52, "id": 7}, {"text": "to", "start": 53, "end": 55, "id": 8}, {"text": "the", "start": 56, "end": 59, "id": 9}, {"text": "brachial", "start": 60, "end": 68, "id": 10}, {"text": "plexus", "start": 69, "end": 75, "id": 11}, {"text": "(", "start": 76, "end": 77, "id": 12}, {"text": "contoured", "start": 77, "end": 86, "id": 13}, {"text": "in", "start": 87, "end": 89, "id": 14}, {"text": "purple", "start": 90, "end": 96, "id": 15}, {"text": ")", "start": 96, "end": 97, "id": 16}, {"text": "from", "start": 98, "end": 102, "id": 17}, {"text": "the", "start": 103, "end": 106, "id": 18}, {"text": "intensitymodulated", "start": 107, "end": 125, "id": 19}, {"text": "radiotherapy", "start": 126, "end": 138, "id": 20}, {"text": "plan", "start": 139, "end": 143, "id": 21}, {"text": "(", "start": 144, "end": 145, "id": 22}, {"text": "a", "start": 145, "end": 146, "id": 23}, {"text": ")", "start": 146, "end": 147, "id": 24}, {"text": "compared", "start": 148, "end": 156, "id": 25}, {"text": "with", "start": 157, "end": 161, "id": 26}, {"text": "the", "start": 162, "end": 165, "id": 27}, {"text": "conventional", "start": 166, "end": 178, "id": 28}, {"text": "radiotherapy", "start": 179, "end": 191, "id": 29}, {"text": "plan", "start": 192, "end": 196, "id": 30}, {"text": "(", "start": 197, "end": 198, "id": 31}, {"text": "b", "start": 198, "end": 199, "id": 32}, {"text": ")", "start": 199, "end": 200, "id": 33}, {"text": "for", "start": 201, "end": 204, "id": 34}, {"text": "the", "start": 205, "end": 208, "id": 35}, {"text": "patient", "start": 209, "end": 216, "id": 36}, {"text": "from", "start": 217, "end": 221, "id": 37}, {"text": "Figure", "start": 222, "end": 228, "id": 38}, {"text": "1", "start": 229, "end": 230, "id": 39}, {"text": ".", "start": 230, "end": 231, "id": 40}, {"text": "Isodose", "start": 232, "end": 239, "id": 41}, {"text": "lines", "start": 240, "end": 245, "id": 42}, {"text": "are", "start": 246, "end": 249, "id": 43}, {"text": "72", "start": 250, "end": 252, "id": 44}, {"text": "Gy", "start": 253, "end": 255, "id": 45}, {"text": "(", "start": 256, "end": 257, "id": 46}, {"text": "grey", "start": 257, "end": 261, "id": 47}, {"text": ")", "start": 261, "end": 262, "id": 48}, {"text": ",", "start": 262, "end": 263, "id": 49}, {"text": "70", "start": 264, "end": 266, "id": 50}, {"text": "Gy", "start": 267, "end": 269, "id": 51}, {"text": "(", "start": 270, "end": 271, "id": 52}, {"text": "red", "start": 271, "end": 274, "id": 53}, {"text": ")", "start": 274, "end": 275, "id": 54}, {"text": ",", "start": 275, "end": 276, "id": 55}, {"text": "66", "start": 277, "end": 279, "id": 56}, {"text": "Gy", "start": 280, "end": 282, "id": 57}, {"text": "(", "start": 283, "end": 284, "id": 58}, {"text": "khaki", "start": 284, "end": 289, "id": 59}, {"text": ")", "start": 289, "end": 290, "id": 60}, {"text": ",", "start": 290, "end": 291, "id": 61}, {"text": "60", "start": 292, "end": 294, "id": 62}, {"text": "Gy", "start": 295, "end": 297, "id": 63}, {"text": "(", "start": 298, "end": 299, "id": 64}, {"text": "green", "start": 299, "end": 304, "id": 65}, {"text": ")", "start": 304, "end": 305, "id": 66}, {"text": ",", "start": 305, "end": 306, "id": 67}, {"text": "56", "start": 307, "end": 309, "id": 68}, {"text": "Gy", "start": 310, "end": 312, "id": 69}, {"text": "(", "start": 313, "end": 314, "id": 70}, {"text": "light", "start": 314, "end": 319, "id": 71}, {"text": "blue", "start": 320, "end": 324, "id": 72}, {"text": ")", "start": 324, "end": 325, "id": 73}, {"text": ",", "start": 325, "end": 326, "id": 74}, {"text": "and", "start": 327, "end": 330, "id": 75}, {"text": "30", "start": 331, "end": 333, "id": 76}, {"text": "Gy", "start": 334, "end": 336, "id": 77}, {"text": "(", "start": 337, "end": 338, "id": 78}, {"text": "purple", "start": 338, "end": 344, "id": 79}, {"text": ")", "start": 344, "end": 345, "id": 80}, {"text": ".", "start": 345, "end": 346, "id": 81}]}
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{"pdf_hash": "8af8869d9a0d2e21380ad476ab16e2f716cc80b3", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Fig 4. Dedifferentiated chondrosarcoma of the right pelvis in a 58-year-old man (Case 15). (A). Anteroposterior radiograph demonstrated osteolytic bone destruction and a soft tissue mass without chondral or osteoid matrix mineralization. (B). CT showed punctate chondral matrix mineralization in the intraosseous medullary cavity, which might be high-grade chondrosarcoma. (C). Fat-suppressed coronal T2-weighted image showed a clear demarcation between predominant reduced signal intensity (dedifferentiated component) and chondral signal intensity. (D). 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{"pdf_hash": "4e0c006309a6bb798ab3447adfb3cf126995d4ed", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 MRI (A Axial plane R\u2013L, B sagittal plane; T2 weighted image, TR 2500,TE100). Abnormally high signal intensities present in the right side dominant, bilateral pontine tegmentum, and extend slightly to the midbrain and medulla.", "width": 1034, "height": 636, "subcaptions": {"a": [4, 5, 6, 7, 8, 9], "b": [11, 12, 13]}, "subfigures": [{"id": "dc5867b1-10e3-41a3-b2d2-117a3424ae6f", "label": "a", "points": [[2.5, 3.3], [2.5, 615.8], [531.7, 615.8], [531.7, 3.3]], "color": "yellow"}, {"id": "da42d6bb-f2b7-486c-9e01-f11f64a16ba2", "label": "b", "points": [[539.9, 3.3], [539.9, 614.2], [1029.9, 614.2], [1029.9, 3.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "MRI", "start": 9, "end": 12, "id": 2}, {"text": "(", "start": 13, "end": 14, "id": 3}, {"text": "A", "start": 14, "end": 15, "id": 4}, {"text": "Axial", "start": 16, "end": 21, "id": 5}, {"text": "plane", "start": 22, "end": 27, "id": 6}, {"text": "R", "start": 28, "end": 29, "id": 7}, {"text": "\u2013", "start": 29, "end": 30, "id": 8}, {"text": "L", "start": 30, "end": 31, "id": 9}, {"text": ",", "start": 31, "end": 32, "id": 10}, {"text": "B", "start": 33, "end": 34, "id": 11}, {"text": "sagittal", "start": 35, "end": 43, "id": 12}, {"text": "plane", "start": 44, "end": 49, "id": 13}, {"text": ";", "start": 49, "end": 50, "id": 14}, {"text": "T2", "start": 51, "end": 53, "id": 15}, {"text": "weighted", "start": 54, "end": 62, "id": 16}, {"text": "image", "start": 63, "end": 68, "id": 17}, {"text": ",", "start": 68, "end": 69, "id": 18}, {"text": "TR", "start": 70, "end": 72, "id": 19}, {"text": "2500,TE100", "start": 73, "end": 83, "id": 20}, {"text": ")", "start": 83, "end": 84, "id": 21}, {"text": ".", "start": 84, "end": 85, "id": 22}, {"text": "Abnormally", "start": 86, "end": 96, "id": 23}, {"text": "high", "start": 97, "end": 101, "id": 24}, {"text": "signal", "start": 102, "end": 108, "id": 25}, {"text": "intensities", "start": 109, "end": 120, "id": 26}, {"text": "present", "start": 121, "end": 128, "id": 27}, {"text": "in", "start": 129, "end": 131, "id": 28}, {"text": "the", "start": 132, "end": 135, "id": 29}, {"text": "right", "start": 136, "end": 141, "id": 30}, {"text": "side", "start": 142, "end": 146, "id": 31}, {"text": "dominant", "start": 147, "end": 155, "id": 32}, {"text": ",", "start": 155, "end": 156, "id": 33}, {"text": "bilateral", "start": 157, "end": 166, "id": 34}, {"text": "pontine", "start": 167, "end": 174, "id": 35}, {"text": "tegmentum", "start": 175, "end": 184, "id": 36}, {"text": ",", "start": 184, "end": 185, "id": 37}, {"text": "and", "start": 186, "end": 189, "id": 38}, {"text": "extend", "start": 190, "end": 196, "id": 39}, {"text": "slightly", "start": 197, "end": 205, "id": 40}, {"text": "to", "start": 206, "end": 208, "id": 41}, {"text": "the", "start": 209, "end": 212, "id": 42}, {"text": "midbrain", "start": 213, "end": 221, "id": 43}, {"text": "and", "start": 222, "end": 225, "id": 44}, {"text": "medulla", "start": 226, "end": 233, "id": 45}, {"text": ".", "start": 233, "end": 234, "id": 46}]}
{"pdf_hash": "6666d4ceaa7ae45711a4bdfd9bcf2652fc97a24d", "fig_key": "Figure8", "fig_uri": "6-Figure8-1.png", "text": "Fig. 8 Axial T2 FSE (a) and T1 post-contrast (b) CT images demonstrate a large, well-defined expansile mass centered within the right carotid space (white arrowhead). The lesion is heterogeneously hyperintense on T2 and avidly enhances post-contrast. The flow voids of the right internal and external carotid arteries are displaced together anteromedially (white arrows). Axial 2D time-of-flight MR angiography (c) demonstrates the mass (white arrowheads), as well as clearly delineating its resultant mass effect exerted upon the right ICA and ECA, which are pushed together anteriorly within the neck (white arrows). 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{"pdf_hash": "e70e2ae1feecd5711106ecae8e76ee390445e530", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. The endoscopic appearance of a small bowel gastrointestinal stromal tumor (GIST). The endoscopic appearance determined with double-balloon endoscopy (DBE) (A) and capsule endoscopy (CE) (B) showed a round, smooth surface tumor with ulceration on the top. The endoscopic appearance determined with DBE (C) and CE (D) revealed a round, smooth tumor with umbilication.", "width": 962, "height": 950, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "b": [17, 18, 19, 20, 21, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53], "c": [68, 69, 70, 71, 72, 73, 74, 75, 76, 54, 55, 56, 57, 58, 59, 60, 61, 62], "d": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 54, 55, 56, 57, 58]}, "subfigures": [{"id": "e4862900-82d5-4dd4-ac00-8c94f3e2ac23", "label": "a", "points": [[-0.8, 0], [-0.8, 443.8], [465.8, 443.8], [465.8, 0]], "color": "yellow"}, {"id": "96a4c692-185b-42c1-b056-9e6e24bc1a51", "label": "b", "points": [[482.5, 0], [482.5, 443.8], [941.5, 443.8], [941.5, 0]], "color": "cyan"}, {"id": "09c209a4-360c-4b01-bc0e-762b7128eb33", "label": "c", "points": [[-0.8, 454.4], [-0.8, 916.4], [468.8, 916.4], [468.8, 454.4]], "color": 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{"pdf_hash": "ecd2705ef8a4c9902b1d810777f517197145bc28", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "Fig. 7. Twelve-month follow-up CT scan of patient 6, a 3-level PD-L case operated on by the PHO technique, showing late formation of a vertical sclerotic band in the nonfractured L5 vertebral body on axial CT reconstruction (A). One should note the similarities between the sclerosis at this level and what is seen in the fractured L4 vertebral body at the level above. Twelve-month follow-up CT scan of patient 1 (B). One should note that the sclerotic development is seen only between 2 adjacent keels. 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{"pdf_hash": "e7e3f6cfc865717b603c65672d452b822f150143", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. (A) PA X-ray image of the thoracic spine obtained postoperatively. (B) Lateral X-ray image of the thoracic spine obtained postoperatively. PA = posteroanterior.", "width": 1340, "height": 870, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32]}, "subfigures": [{"id": "0c5778c1-b365-43d1-8c55-604b0af806f5", "label": "a", "points": [[39.2, 18.7], [39.2, 840], [663.7, 840], [663.7, 18.7]], "color": "yellow"}, {"id": "a76a79ff-f74b-4fd8-9ef3-b1e2d59b30ac", "label": "b", "points": [[682.7, 27.2], [682.7, 831.6], [1300.8, 831.6], [1300.8, 27.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "PA", "start": 14, "end": 16, "id": 6}, {"text": "X", "start": 17, "end": 18, "id": 7}, {"text": "-", "start": 18, "end": 19, "id": 8}, {"text": "ray", "start": 19, "end": 22, "id": 9}, {"text": "image", "start": 23, "end": 28, "id": 10}, {"text": "of", "start": 29, "end": 31, "id": 11}, {"text": "the", "start": 32, "end": 35, "id": 12}, {"text": "thoracic", "start": 36, "end": 44, "id": 13}, {"text": "spine", "start": 45, "end": 50, "id": 14}, {"text": "obtained", "start": 51, "end": 59, "id": 15}, {"text": "postoperatively", "start": 60, "end": 75, "id": 16}, {"text": ".", "start": 75, "end": 76, "id": 17}, {"text": "(", "start": 77, "end": 78, "id": 18}, {"text": "B", "start": 78, "end": 79, "id": 19}, {"text": ")", "start": 79, "end": 80, "id": 20}, {"text": "Lateral", "start": 81, "end": 88, "id": 21}, {"text": "X", "start": 89, "end": 90, "id": 22}, {"text": "-", "start": 90, "end": 91, "id": 23}, {"text": "ray", "start": 91, "end": 94, "id": 24}, {"text": "image", "start": 95, "end": 100, "id": 25}, {"text": "of", "start": 101, "end": 103, "id": 26}, {"text": "the", "start": 104, "end": 107, "id": 27}, {"text": "thoracic", "start": 108, "end": 116, "id": 28}, {"text": "spine", "start": 117, "end": 122, "id": 29}, {"text": "obtained", "start": 123, "end": 131, "id": 30}, {"text": "postoperatively", "start": 132, "end": 147, "id": 31}, {"text": ".", "start": 147, "end": 148, "id": 32}, {"text": "PA", "start": 149, "end": 151, "id": 33}, {"text": "=", "start": 152, "end": 153, "id": 34}, {"text": "posteroanterior", "start": 154, "end": 169, "id": 35}, {"text": ".", "start": 169, "end": 170, "id": 36}]}
{"pdf_hash": "0b7bd4a11f44908653fe2f91dbba538fbaa7eb3b", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig. 1 Two distinct responder lines reveal Nop-tTA expression beyond the entorhinal cortex. a Using a nuclear localized lacZ reporter, we detected substantial expression outside the areas where the Nop-tTA driver was known to be active. b Using an H2B-GFP reporter, expression was detected in many of the same areas as in the", "width": 1354, "height": 530, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "b": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "83a67842-b01a-4b11-bb32-1a5ae2bfc74d", "label": "a", "points": [[7.6, -0.4], [7.6, 247.8], [1348.7, 247.8], [1348.7, -0.4]], "color": "yellow"}, {"id": "e87069d8-6e09-43d5-b497-449ef08dde54", "label": "b", "points": [[7.6, 264.9], [7.6, 521.6], [1353, 521.6], [1353, 264.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Two", "start": 7, "end": 10, "id": 3}, {"text": "distinct", "start": 11, "end": 19, "id": 4}, {"text": "responder", "start": 20, "end": 29, "id": 5}, {"text": "lines", "start": 30, "end": 35, "id": 6}, {"text": "reveal", "start": 36, "end": 42, "id": 7}, {"text": "Nop", "start": 43, "end": 46, "id": 8}, {"text": "-", "start": 46, "end": 47, "id": 9}, {"text": "tTA", "start": 47, "end": 50, "id": 10}, {"text": "expression", "start": 51, "end": 61, "id": 11}, {"text": "beyond", "start": 62, "end": 68, "id": 12}, {"text": "the", "start": 69, "end": 72, "id": 13}, {"text": "entorhinal", "start": 73, "end": 83, "id": 14}, {"text": "cortex", "start": 84, "end": 90, "id": 15}, {"text": ".", "start": 90, "end": 91, "id": 16}, {"text": "a", "start": 92, "end": 93, "id": 17}, {"text": "Using", "start": 94, "end": 99, "id": 18}, {"text": "a", "start": 100, "end": 101, "id": 19}, {"text": "nuclear", "start": 102, "end": 109, "id": 20}, {"text": "localized", "start": 110, "end": 119, "id": 21}, {"text": "lacZ", "start": 120, "end": 124, "id": 22}, {"text": "reporter", "start": 125, "end": 133, "id": 23}, {"text": ",", "start": 133, "end": 134, "id": 24}, {"text": "we", "start": 135, "end": 137, "id": 25}, {"text": "detected", "start": 138, "end": 146, "id": 26}, {"text": "substantial", "start": 147, "end": 158, "id": 27}, {"text": "expression", "start": 159, "end": 169, "id": 28}, {"text": "outside", "start": 170, "end": 177, "id": 29}, {"text": "the", "start": 178, "end": 181, "id": 30}, {"text": "areas", "start": 182, "end": 187, "id": 31}, {"text": "where", "start": 188, "end": 193, "id": 32}, {"text": "the", "start": 194, "end": 197, "id": 33}, {"text": "Nop", "start": 198, "end": 201, "id": 34}, {"text": "-", "start": 201, "end": 202, "id": 35}, {"text": "tTA", "start": 202, "end": 205, "id": 36}, {"text": "driver", "start": 206, "end": 212, "id": 37}, {"text": "was", "start": 213, "end": 216, "id": 38}, {"text": "known", "start": 217, "end": 222, "id": 39}, {"text": "to", "start": 223, "end": 225, "id": 40}, {"text": "be", "start": 226, "end": 228, "id": 41}, {"text": "active", "start": 229, "end": 235, "id": 42}, {"text": ".", "start": 235, "end": 236, "id": 43}, {"text": "b", "start": 237, "end": 238, "id": 44}, {"text": "Using", "start": 239, "end": 244, "id": 45}, {"text": "an", "start": 245, "end": 247, "id": 46}, {"text": "H2B", "start": 248, "end": 251, "id": 47}, {"text": "-", "start": 251, "end": 252, "id": 48}, {"text": "GFP", "start": 252, "end": 255, "id": 49}, {"text": "reporter", "start": 256, "end": 264, "id": 50}, {"text": ",", "start": 264, "end": 265, "id": 51}, {"text": "expression", "start": 266, "end": 276, "id": 52}, {"text": "was", "start": 277, "end": 280, "id": 53}, {"text": "detected", "start": 281, "end": 289, "id": 54}, {"text": "in", "start": 290, "end": 292, "id": 55}, {"text": "many", "start": 293, "end": 297, "id": 56}, {"text": "of", "start": 298, "end": 300, "id": 57}, {"text": "the", "start": 301, "end": 304, "id": 58}, {"text": "same", "start": 305, "end": 309, "id": 59}, {"text": "areas", "start": 310, "end": 315, "id": 60}, {"text": "as", "start": 316, "end": 318, "id": 61}, {"text": "in", "start": 319, "end": 321, "id": 62}, {"text": "the", "start": 322, "end": 325, "id": 63}]}
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{"pdf_hash": "42722a3beaa9d660e3038a9707834723e452dee4", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 a Preoperative AP radiograph showing an intercrest line passing through the L5 vertebra (L5-Non-Seated Group); b and c Postoperative axial CT images showing no pedicle breach (Grade 0 screw) both at the L5 and S1 level", "width": 848, "height": 592, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "c": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "9fb38de9-f31e-44b4-af95-34ce97133185", "label": "a", "points": [[29.5, 26.6], [29.5, 562.4], [415.3, 562.4], [415.3, 26.6]], "color": "yellow"}, {"id": "04e466d1-70fd-465e-9463-a368a70da8ca", "label": "b", "points": [[427.4, 22.6], [427.4, 266.4], [807.8, 266.4], [807.8, 22.6]], "color": "cyan"}, {"id": "520892e2-9acf-4e74-9289-6aaa163d8237", "label": "c", "points": [[427.4, 278.4], [427.4, 558.4], [810.5, 558.4], [810.5, 278.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Preoperative", "start": 9, "end": 21, "id": 4}, {"text": "AP", "start": 22, "end": 24, "id": 5}, {"text": "radiograph", "start": 25, "end": 35, "id": 6}, {"text": "showing", "start": 36, "end": 43, "id": 7}, {"text": "an", "start": 44, "end": 46, "id": 8}, {"text": "intercrest", "start": 47, "end": 57, "id": 9}, {"text": "line", "start": 58, "end": 62, "id": 10}, {"text": "passing", "start": 63, "end": 70, "id": 11}, {"text": "through", "start": 71, "end": 78, "id": 12}, {"text": "the", "start": 79, "end": 82, "id": 13}, {"text": "L5", "start": 83, "end": 85, "id": 14}, {"text": "vertebra", "start": 86, "end": 94, "id": 15}, {"text": "(", "start": 95, "end": 96, "id": 16}, {"text": "L5-Non", "start": 96, "end": 102, "id": 17}, {"text": "-", "start": 102, "end": 103, "id": 18}, {"text": "Seated", "start": 103, "end": 109, "id": 19}, {"text": "Group", "start": 110, "end": 115, "id": 20}, {"text": ")", "start": 115, "end": 116, "id": 21}, {"text": ";", "start": 116, "end": 117, "id": 22}, {"text": "b", "start": 118, "end": 119, "id": 23}, {"text": "and", "start": 120, "end": 123, "id": 24}, {"text": "c", "start": 124, "end": 125, "id": 25}, {"text": "Postoperative", "start": 126, "end": 139, "id": 26}, {"text": "axial", "start": 140, "end": 145, "id": 27}, {"text": "CT", "start": 146, "end": 148, "id": 28}, {"text": "images", "start": 149, "end": 155, "id": 29}, {"text": "showing", "start": 156, "end": 163, "id": 30}, {"text": "no", "start": 164, "end": 166, "id": 31}, {"text": "pedicle", "start": 167, "end": 174, "id": 32}, {"text": "breach", "start": 175, "end": 181, "id": 33}, {"text": "(", "start": 182, "end": 183, "id": 34}, {"text": "Grade", "start": 183, "end": 188, "id": 35}, {"text": "0", "start": 189, "end": 190, "id": 36}, {"text": "screw", "start": 191, "end": 196, "id": 37}, {"text": ")", "start": 196, "end": 197, "id": 38}, {"text": "both", "start": 198, "end": 202, "id": 39}, {"text": "at", "start": 203, "end": 205, "id": 40}, {"text": "the", "start": 206, "end": 209, "id": 41}, {"text": "L5", "start": 210, "end": 212, "id": 42}, {"text": "and", "start": 213, "end": 216, "id": 43}, {"text": "S1", "start": 217, "end": 219, "id": 44}, {"text": "level", "start": 220, "end": 225, "id": 45}]}
{"pdf_hash": "d67515055e6f91c53cbd8f6ec8fa16377257eb55", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. MR imaging findings one month after thiamine treatment. Axial T2-weighted (a, e), FLAIR (b, f), and DWI (c, g) images show normal signal intensity in the medial thalami (a\u2013c), as well as in the tectum of the midbrain and the periaquaeductal area (e\u2013g). 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{"pdf_hash": "6fd9e948083c09edd5672c797a329174c2ca057e", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. RNV is generated in OIR mice. (A) Fundus photography facilitated visualization of the inner surfaces of the eyes of the WT and OIR mice. The representative images indicate the large number of pale neovascular vessels that had grown into the vitreous cavity in the OIR mice, compared with the WT mice. (B) Representative H&E staining of retinal sections. A large number of the neovascular nuclei were present beyond the internal limiting membrane in the OIR mice, while there were only a few neovascular nuclei in the WT mice. (C) The number of outgrowth endothelial cells in the retinas was calculated using Image-Pro Plus software. The number of neovascular nuclei in the OIR mice was significantly greater compared with that of the control mice. Data are presented as the mean \u00b1 standard deviation of the mean (n=6 mice per group). *** P<0.001 vs. WT mice. GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium. 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{"pdf_hash": "cbc0a52a89cde515525530381bfd69dc5692a185", "fig_key": "Figure2", "fig_uri": "16-Figure2-1.png", "text": "Figure 2. Examination of cardiac cytoarchitecture demonstrates that the migrating myocardium is a polarized epithelium. (A,B) Confocal images of transverse sections, dorsal to the top, of Tg (cmlc2:egfp) [43] embryos at the 20-somite stage, as in [29]. Expression of Tg(cmlc2:egfp) (pseudocolored blue) indicates bilateral populations of cardiomyocytes in the process of cardiac fusion. Immunohistochemistry for \u03b2-catenin (red), PRKCi (green, A), and Fibronectin (green, B) indicates protein localization. (A) At this stage, cardiomyocytes exhibit clear apicobasal polarity, with \u03b2-catenin localized basolaterally and PRKCi localized apicolaterally. (B) Fibronectin deposition is evident adjacent to the basal surface of the myocardial epithelia. Images provided by L. Trinh and D. 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{"pdf_hash": "0100916d15e78073a067075c04512c50cc77e574", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 An 82-year-old woman with primary pancreatic lymphoma, biopsy-proven diffuse large B-cell lymphoma. a Precontrast CT shows ill-defined pancreas head mass (white arrow). b Pancreatic phase dynamic contrast-enhanced CT shows round-shaped and slightly low density mass (white arrow). c Fat-suppressed T2-weighted MR image shows a circumscribed homogeneously hyperintense mass in the pancreatic head (white arrow). d Fat-suppressed T1-weighted MR image", "width": 1078, "height": 650, "subcaptions": {"a": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59], "c": [60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81], "d": [82, 83, 84, 85, 86, 87, 88], "e": [0]}, "subfigures": [{"id": "ebf3a190-3c1c-44eb-9953-9275f3e1cff3", "label": "a", 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{"pdf_hash": "af818a6cf2dfbdc405390247b5cd8df4beac1211", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4. Transverse sections of susceptible clone NC11505 at 3 time points (3 weeks, 5 weeks, and 7 weeks) post-inoculation (PI) depicting anatomical responses to inoculation with a conidial suspension of Sphaerulina musiva. (A) Bright field micrograph of necrotic stem lesion 3 weeks PI. Necrotic area (Nec) bounded by layer of impervious tissue (IT indicated with arrow). (B) Fluorescent micrograph of necrotic lesion 3 weeks PI. IT layer visible as light purple fluorescence (indicated with arrows). (C) Bright field micrograph of necrotic lesion 5 weeks PI. Nec is bounded by a layer of necrophylactic periderm (NP; indicated with arrow). (D) Fluorescent micrograph of necrotic lesion 5 weeks PI. Nec is bounded by IT layer and NP layer (indicated with arrows). (E) Bright field micrograph of necrotic stem 7 weeks PI. Entire cortex (COX) is necrotic and filled with collapsed cells. (F) Fluorescent micrograph of necrotic lesion 7 weeks PI. NP and IT are absent from the Nec. Blue auto-fluorescence viewed under ultraviolet light. Filter parameters: Excitation filter G 365, Beam Splitter FT 395, Emission filter BP 445/50. Green auto-fluorescence viewed under ultraviolet light. Filter parameters: Excitation filter BP 450\u2013490, Beam Splitter FT 510, Emission filter BP 515\u2013565. P = periderm. Pf = primary phloem fiber. X = Xylem. VC = Vascular cambium. 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{"pdf_hash": "9d7e55b6da7e9caf2f3cfddac1202a3c5df8946e", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Retinal histologic findings with toluidine blue light microscopy 7 days after intravitreal injection of 0.05 mL of BBG-D2O in the right eye and 0.05 mL of BSS in the left eye. Eye E1 OD (Left image): Retinal microstructure: normal; vitreous cells or alterations: normal; NFL: focal vacuolization; ganglion cells and IPL: normal; bipolar cells/INL: focal vacuolization and edema; outer plexiform layer, Photoreceptors/ONL, PIS: normal; POS: artifact; RPE, choriocapillaris/choroid: normal Eye E2 OD (Middle Image): retinal microstructure: hyalocytes in the internal surface of the retina; NFL: focal vacuolization, artifact; ganglion cells, IPL: focal vacuolization; bipolar cells/INL: normal; outer plexiform layer: thinning, between this and ONL an area of swelling; Photoreceptors/ONL, PIS, POS, RPE, choriocapillaris/choroid: normal Eye E3 OS (Right image): Retinal microstructure: normal; vitreous cells or alterations: normal; NFL and ganglion cells: focal vacuolization; IPL, bipolar cells/INL, outer plexiform layer, photoreceptors/ONL, PIS, POS: normal, just slight distortion due to artifact, but the layer and cells are fine; RPE and choriocapillaris/choroid: normal BBG, brilliant blue G; D2O, Deuterium; BSS, balanced salt solution; OD, right eye; OS, left eye; NFL, nerve fiber layer; IPL, inner plexiform layer; INL, inner nuclear layer; ONL, outer nuclear layer; PIS, photoreceptor inner segment; POS, photoreceptor outer segment; RPE, retinal pigment epithelium", "width": 1300, "height": 344, "subcaptions": {"a": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101], "b": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "c": [174, 175, 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{"pdf_hash": "5d5fbfc209c8300b459cb5ac86345bf8db26d9ef", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Positron emission tomography scan (left) showing a positive supraclavicular lymph node. Computed tomography scan (right) of the same area illustrates the superior ability of positron emission tomography to identify metastatic disease.", "width": 676, "height": 532, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39]}, "subfigures": [{"id": "62997770-2fd6-4c9e-9013-21073fb10823", "label": "a", "points": [[2.7, -0.4], [2.7, 510.1], [333.7, 510.1], [333.7, -0.4]], "color": "yellow"}, {"id": "44f04ad5-840c-428e-8ea5-a291b9c37c4c", "label": "b", "points": [[341.2, 2.8], [341.2, 512.3], [674.4, 512.3], [674.4, 2.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Positron", "start": 10, "end": 18, "id": 3}, {"text": "emission", "start": 19, "end": 27, "id": 4}, {"text": "tomography", "start": 28, "end": 38, "id": 5}, {"text": "scan", "start": 39, "end": 43, "id": 6}, {"text": "(", "start": 44, "end": 45, "id": 7}, {"text": "left", "start": 45, "end": 49, "id": 8}, {"text": ")", "start": 49, "end": 50, "id": 9}, {"text": "showing", "start": 51, "end": 58, "id": 10}, {"text": "a", "start": 59, "end": 60, "id": 11}, {"text": "positive", "start": 61, "end": 69, "id": 12}, {"text": "supraclavicular", "start": 70, "end": 85, "id": 13}, {"text": "lymph", "start": 86, "end": 91, "id": 14}, {"text": "node", "start": 92, "end": 96, "id": 15}, {"text": ".", "start": 96, "end": 97, "id": 16}, {"text": "Computed", "start": 98, "end": 106, "id": 17}, {"text": "tomography", "start": 107, "end": 117, "id": 18}, {"text": "scan", "start": 118, "end": 122, "id": 19}, {"text": "(", "start": 123, "end": 124, "id": 20}, {"text": "right", "start": 124, "end": 129, "id": 21}, {"text": ")", "start": 129, "end": 130, "id": 22}, {"text": "of", "start": 131, "end": 133, "id": 23}, {"text": "the", "start": 134, "end": 137, "id": 24}, {"text": "same", "start": 138, "end": 142, "id": 25}, {"text": "area", "start": 143, "end": 147, "id": 26}, {"text": "illustrates", "start": 148, "end": 159, "id": 27}, {"text": "the", "start": 160, "end": 163, "id": 28}, {"text": "superior", "start": 164, "end": 172, "id": 29}, {"text": "ability", "start": 173, "end": 180, "id": 30}, {"text": "of", "start": 181, "end": 183, "id": 31}, {"text": "positron", "start": 184, "end": 192, "id": 32}, {"text": "emission", "start": 193, "end": 201, "id": 33}, {"text": "tomography", "start": 202, "end": 212, "id": 34}, {"text": "to", "start": 213, "end": 215, "id": 35}, {"text": "identify", "start": 216, "end": 224, "id": 36}, {"text": "metastatic", "start": 225, "end": 235, "id": 37}, {"text": "disease", "start": 236, "end": 243, "id": 38}, {"text": ".", "start": 243, "end": 244, "id": 39}]}
{"pdf_hash": "4b6f2112b58f45d5ea08df91d3aaca66886dcd31", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. MRI of the abdominal aorta in control and atherosclerotic rabbits using a 0.2-T MRI system. Control rabbit coronal view (A) and enlarged image axial view (A.1) with position indicated by indicated by line A.1, showing normal vessel wall without plaque indicated by the white arrow. Atherosclerotic rabbit coronal view (B), sagittal views (C), and enlarged image axial views (C.1, C.2, C.3 corresponding respectively to positions indicated by lines C.1, C.2, C.3), showing thickened vessel wall and crescent-shaped plaque (white arrows).", "width": 922, "height": 826, "subcaptions": {"a": [19, 20, 21, 22, 23, 24, 25], "d": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54], "b": [55, 56, 57, 58, 59, 60, 61], "c": [64, 65, 66, 67, 63], "e": [70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107]}, "subfigures": [{"id": "bddc3b01-5c0f-4ae2-a9af-9c7f0de4cd32", "label": "b", "points": [[332.8, 4.4], [332.8, 317.5], [644.5, 317.5], [644.5, 4.4]], "color": "cyan"}, {"id": "dca299e6-86fd-4212-87a5-211607e83a47", "label": "c", "points": [[332.8, 355.4], [332.8, 818.6], [641.6, 818.6], [641.6, 355.4]], "color": 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{"pdf_hash": "4a175aeffeb413fd16736ccc50e617438aafde26", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5. Lymphatic endothelial cell damage following afferent DEFINITYH injection. 4-month-old TNF-Tg and WT mice received a footpad injection of DEFINITYH or saline, and were subjected to US imaging as described in Materials & Methods. 4 weeks later, the injected footpad received an injection of Evan's blue dye to identify the lymphatic vessels afferent to the PLN, which were harvested and processed for transmission electron microscopy. Representative images are shown to illustrated the endothelial cells (EC); smooth muscle cells (SMC); and lumen (L) of the lymphatic vessel. Note the damaged lymphatic vessel in the DEFINITY H injected mice (A,B), as evidenced by the cell detachment (arrows in A), and obviously large vacuoles and intraluminal protrusions (arrow heads in B), as well as the atrophic appearance of the smooth muscle cell (B). In contrast, the lymph vessels exposed to saline showed attached endothelial cells and minor vacuoles (arrow head in C), but also have obvious intraluminal protrusions (arrow head in C). 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{"pdf_hash": "c0ebfb7992af436527f89311e50425ac38d02c8c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. T2-weighted and gadolinium enhanced T1-weighted cervical MRI in the patient. (A) Initial cervical spine MRI (magnetic resonance image) revealed increased T2 signal from C4 to C6 level, edematous expansion of the cord and intense nodular enhancement. Based on the MRI, spinal cord tumor, demyelinating disease and acute tranverse myelitis were suspected. (B) One month later, the follow-up spinal MRI showed the extended lesion relative to previous MRI, and which highly suggested the spinal cord tumor such as intramedullay astrocytoma. (C) Demonstrates cervical spine MRI after laminectomy and tissue biopsy. (D) The patient was treated with high-dose corticosteroid and immunosuppressant for over 2 yr and spinal cord lesion was much resolved in MRI.", "width": 1380, "height": 732, "subcaptions": {"a": [15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64], "b": [65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99], "c": [100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112], "d": [113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140]}, "subfigures": [{"id": "d96fa5bd-dd77-43f8-a393-313fb8fe70a2", "label": "a", "points": [[6.6, 36.7], [6.6, 379], [688.9, 379], [688.9, 36.7]], "color": "yellow"}, {"id": "44fc06a2-1f6f-41f5-83fb-867f4086c616", "label": "b", "points": 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{"pdf_hash": "d077452bb721b4477bfc96c28a686e9f65c97712", "fig_key": "Figure4", "fig_uri": "9-Figure4-1.png", "text": "Figure 4. Images stained using silver stain for reticulin fibers and counterstained using nuclear fast red solution. (A and C) Reconstructed stitched pituitary photomicrographs from two control pituitaries. Original magnification, 3100. (B and D) Enlarged photomicrographs from sections of (A) and (C), respectively. Original magnification, 3400. The acinar pattern of reticulin staining is identified in (B) and (D). 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{"pdf_hash": "c36fab06c91f128af1307de458496fcac3eb7ec1", "fig_key": "Figure4", "fig_uri": "14-Figure4-1.png", "text": "Fig 4. Fluorescent micrographs illustrating CSE-immunoreactivity (ir) in mouse colon (A-C), liver (D), and brain (E-I). In the colon, specific staining was present in myenteric neurons (arrows) revealed by both the rabbit anti-CSE (A) and mouse anti-CSE antisera (B and C). B) Cross section of the mouse colon revealed CSE-ir in the mucosa and myenteric neurons. C) An en face preparation of the colonic muscle layers demonstrate CSE-ir neuronal cell bodies. D) CSE-ir in the liver was localized to hepatocytes and within the Space of Disse. E) Coronal section of the striatum revealed CSE-ir in neuronal cell bodies and within the fibers of passage in the internal capsule. Some neurons expressed CSE-ir in proximal processes. F) Coronal section of the hippocampus revealed CSE-ir in neuronal cell bodies. G) Neuronal cell bodies in the mouse neocortex revealed CSE-ir. H) A section adjacent to that in G was stained with an antibody solution that was incubated for 2 h with recombinant CSE (Abnova). This preabsorption reduced or blocked specific immunoreactivity demonstrating the specificity of the antibody in this study. Matched micrographs (G and H) were taken with identical camera settings. I) Montage of a parasaggital section of the mouse brain with CSE-ir in major fiber tracts. Neuronal cell bodies in neocortex and Purkinje cells in the cerebellum can be observed in this section. Scale bars: A, E, G, and H = 50 \u03bcm; B, C and D = 100 \u03bcm; F = 250 \u03bcm; I = 2 mm.", "width": 200, "height": 178, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89], "c": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108], "d": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 21, 22, 23, 24, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "e": [128, 129, 130, 3, 4, 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{"pdf_hash": "5d10610d8b5f3c8d23bd5f577343007fd7f0e81a", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Macroscopic and microscopic findings of the skin lesion. (A) Palpable purpura progressed rapidly into extensive ecchymoses on the back (left), trunk (right upper), and right foot and ankle (right lower). (B) A fascia biopsy of the right crus showing fresh fibrin thrombi (arrows), including neutrophils within a small dilated vessel [Hematoxylin and Eosin (H&E) staining; original magnification 20\u00d7]. (C) A skin biopsy showing infiltration of neutrophils with karyorrhectic nuclear debris, and extravasation of erythrocytes around small vessels in the dermis, leading to a diagnosis of leukocytoclastic vasculitis (H&E staining; original magnification 20\u00d7). 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{"pdf_hash": "0c2a332a4dc15bb66c19a53600dc8e43ae210812", "fig_key": "Figure6", "fig_uri": "6-Figure6-1.png", "text": "FIGURE 6. Images with ultrasound biomicroscopy for patient A whose presurgical refractive error was j18.50 D. (A) Anterior chamber depth was 2.81 mm and ICL vault was 0.10 mm. (B) A representative quadrant.", "width": 1428, "height": 460, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39]}, "subfigures": [{"id": "ef0a1f05-a303-4f63-b1fa-3ec39cfbd9bd", "label": "a", "points": [[5.6, 6.8], [5.6, 419.6], [709.5, 419.6], [709.5, 6.8]], "color": "yellow"}, {"id": "0963371e-ae0a-4dfe-ad47-5a1d1f300319", "label": "b", "points": [[714, 4.5], [714, 424.1], [1422.4, 424.1], [1422.4, 4.5]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Images", "start": 10, "end": 16, "id": 3}, {"text": "with", "start": 17, "end": 21, "id": 4}, {"text": "ultrasound", "start": 22, "end": 32, "id": 5}, {"text": "biomicroscopy", "start": 33, "end": 46, "id": 6}, {"text": "for", "start": 47, "end": 50, "id": 7}, {"text": "patient", "start": 51, "end": 58, "id": 8}, {"text": "A", "start": 59, "end": 60, "id": 9}, {"text": "whose", "start": 61, "end": 66, "id": 10}, {"text": "presurgical", "start": 67, "end": 78, "id": 11}, {"text": "refractive", "start": 79, "end": 89, "id": 12}, {"text": "error", "start": 90, "end": 95, "id": 13}, {"text": "was", "start": 96, "end": 99, "id": 14}, {"text": "j18.50", "start": 100, "end": 106, "id": 15}, {"text": "D.", "start": 107, "end": 109, "id": 16}, {"text": "(", "start": 110, "end": 111, "id": 17}, {"text": "A", "start": 111, "end": 112, "id": 18}, {"text": ")", "start": 112, "end": 113, "id": 19}, {"text": "Anterior", "start": 114, "end": 122, "id": 20}, {"text": "chamber", "start": 123, "end": 130, "id": 21}, {"text": "depth", "start": 131, "end": 136, "id": 22}, {"text": "was", "start": 137, "end": 140, "id": 23}, {"text": "2.81", "start": 141, "end": 145, "id": 24}, {"text": "mm", "start": 146, "end": 148, "id": 25}, {"text": "and", "start": 149, "end": 152, "id": 26}, {"text": "ICL", "start": 153, "end": 156, "id": 27}, {"text": "vault", "start": 157, "end": 162, "id": 28}, {"text": "was", "start": 163, "end": 166, "id": 29}, {"text": "0.10", "start": 167, "end": 171, "id": 30}, {"text": "mm", "start": 172, "end": 174, "id": 31}, {"text": ".", "start": 174, "end": 175, "id": 32}, {"text": "(", "start": 176, "end": 177, "id": 33}, {"text": "B", "start": 177, "end": 178, "id": 34}, {"text": ")", "start": 178, "end": 179, "id": 35}, {"text": "A", "start": 180, "end": 181, "id": 36}, {"text": "representative", "start": 182, "end": 196, "id": 37}, {"text": "quadrant", "start": 197, "end": 205, "id": 38}, {"text": ".", "start": 205, "end": 206, "id": 39}]}
{"pdf_hash": "5fbd5b45173259a2186089f27ce456581e1a1f99", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 (a) An initially normal posteroanterior chest radiograph. (b) An anteroposterior pelvis radiograph showing normal hip and sacroiliac joints on admission, with a tiny bone island on the right ischial area (arrow).", "width": 650, "height": 1048, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11], "b": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "cb3b6b9d-d5ad-426c-9ba2-328017601d99", "label": "a", "points": [[1.2, 8.6], [1.2, 524], [645, 524], [645, 8.6]], "color": "yellow"}, {"id": "abb598d5-09af-46a9-a3b3-c3e373882206", "label": "b", "points": [[4.3, 532.3], [4.3, 1045.7], [646.1, 1045.7], [646.1, 532.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "(", "start": 9, "end": 10, "id": 2}, {"text": "a", "start": 10, "end": 11, "id": 3}, {"text": ")", "start": 11, "end": 12, "id": 4}, {"text": "An", "start": 13, "end": 15, "id": 5}, {"text": "initially", "start": 16, "end": 25, "id": 6}, {"text": "normal", "start": 26, "end": 32, "id": 7}, {"text": "posteroanterior", "start": 33, "end": 48, "id": 8}, {"text": "chest", "start": 49, "end": 54, "id": 9}, {"text": "radiograph", "start": 55, "end": 65, "id": 10}, {"text": ".", "start": 65, "end": 66, "id": 11}, {"text": "(", "start": 67, "end": 68, "id": 12}, {"text": "b", "start": 68, "end": 69, "id": 13}, {"text": ")", "start": 69, "end": 70, "id": 14}, {"text": "An", "start": 71, "end": 73, "id": 15}, {"text": "anteroposterior", "start": 74, "end": 89, "id": 16}, {"text": "pelvis", "start": 90, "end": 96, "id": 17}, {"text": "radiograph", "start": 97, "end": 107, "id": 18}, {"text": "showing", "start": 108, "end": 115, "id": 19}, {"text": "normal", "start": 116, "end": 122, "id": 20}, {"text": "hip", "start": 123, "end": 126, "id": 21}, {"text": "and", "start": 127, "end": 130, "id": 22}, {"text": "sacroiliac", "start": 131, "end": 141, "id": 23}, {"text": "joints", "start": 142, "end": 148, "id": 24}, {"text": "on", "start": 149, "end": 151, "id": 25}, {"text": "admission", "start": 152, "end": 161, "id": 26}, {"text": ",", "start": 161, "end": 162, "id": 27}, {"text": "with", "start": 163, "end": 167, "id": 28}, {"text": "a", "start": 168, "end": 169, "id": 29}, {"text": "tiny", "start": 170, "end": 174, "id": 30}, {"text": "bone", "start": 175, "end": 179, "id": 31}, {"text": "island", "start": 180, "end": 186, "id": 32}, {"text": "on", "start": 187, "end": 189, "id": 33}, {"text": "the", "start": 190, "end": 193, "id": 34}, {"text": "right", "start": 194, "end": 199, "id": 35}, {"text": "ischial", "start": 200, "end": 207, "id": 36}, {"text": "area", "start": 208, "end": 212, "id": 37}, {"text": "(", "start": 213, "end": 214, "id": 38}, {"text": "arrow", "start": 214, "end": 219, "id": 39}, {"text": ")", "start": 219, "end": 220, "id": 40}, {"text": ".", "start": 220, "end": 221, "id": 41}]}
{"pdf_hash": "54e6c3f5bdfa00b75f812c77903ae4f34f237897", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig. 2. Probabilistic tractography between the SC and the amygdala via the pulvinar in one representative participant from the first group. A: three-dimensional (3D) reconstructions of the tract (shown in red) linking the SC (shown in yellow) and the amygdala (shown in green) via the pulvinar (shown in blue). Tracts have been thresholded by 10% (see METHODS for details). The individual structures and tracts in the 3D reconstructions have been dilated by 2\u20134 mm for visualization purposes only. Coronal (B) and sagittal (C) sections show the location of the tract relative to the amygdala (green), pulvinar (blue), and SC (yellow). 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{"pdf_hash": "3c9b34a204de0ae107cc11f6854aadb808942f63", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 High definition white light endoscopy view. A: A depressed lesion with mucosal discoloration due to early gastric cancer; B: High definition white light endoscopy view of early gastric cancer.", "width": 916, "height": 394, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35]}, "subfigures": [{"id": "0498b3fe-a114-47a3-9ffd-f7db51e79ce5", "label": "a", "points": [[-0.7, 2.9], [-0.7, 392.2], [452.2, 392.2], [452.2, 2.9]], "color": "yellow"}, {"id": "7b85997f-e976-4903-8323-277a7d386628", "label": "b", "points": [[468.1, 0], [468.1, 393.6], [912.4, 393.6], [912.4, 0]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "High", "start": 9, "end": 13, "id": 2}, {"text": "definition", "start": 14, "end": 24, "id": 3}, {"text": "white", "start": 25, "end": 30, "id": 4}, {"text": "light", "start": 31, "end": 36, "id": 5}, {"text": "endoscopy", "start": 37, "end": 46, "id": 6}, {"text": "view", "start": 47, "end": 51, "id": 7}, {"text": ".", "start": 51, "end": 52, "id": 8}, {"text": "A", "start": 53, "end": 54, "id": 9}, {"text": ":", "start": 54, "end": 55, "id": 10}, {"text": "A", "start": 56, "end": 57, "id": 11}, {"text": "depressed", "start": 58, "end": 67, "id": 12}, {"text": "lesion", "start": 68, "end": 74, "id": 13}, {"text": "with", "start": 75, "end": 79, "id": 14}, {"text": "mucosal", "start": 80, "end": 87, "id": 15}, {"text": "discoloration", "start": 88, "end": 101, "id": 16}, {"text": "due", "start": 102, "end": 105, "id": 17}, {"text": "to", "start": 106, "end": 108, "id": 18}, {"text": "early", "start": 109, "end": 114, "id": 19}, {"text": "gastric", "start": 115, "end": 122, "id": 20}, {"text": "cancer", "start": 123, "end": 129, "id": 21}, {"text": ";", "start": 129, "end": 130, "id": 22}, {"text": "B", "start": 131, "end": 132, "id": 23}, {"text": ":", "start": 132, "end": 133, "id": 24}, {"text": "High", "start": 134, "end": 138, "id": 25}, {"text": "definition", "start": 139, "end": 149, "id": 26}, {"text": "white", "start": 150, "end": 155, "id": 27}, {"text": "light", "start": 156, "end": 161, "id": 28}, {"text": "endoscopy", "start": 162, "end": 171, "id": 29}, {"text": "view", "start": 172, "end": 176, "id": 30}, {"text": "of", "start": 177, "end": 179, "id": 31}, {"text": "early", "start": 180, "end": 185, "id": 32}, {"text": "gastric", "start": 186, "end": 193, "id": 33}, {"text": "cancer", "start": 194, "end": 200, "id": 34}, {"text": ".", "start": 200, "end": 201, "id": 35}]}
{"pdf_hash": "4c25d87cf7340ef6de08c0a416635b52f0df689e", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 Preoperative and postoperative images of one patient (Case No. 9). a: Sagittal preoperative CT showing the upper tracheal stenosis. b: Postoperative sagittal CT showing the normal trachea. c: The appearance of the suture on the neck", "width": 1342, "height": 510, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "c": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "c0b8045f-a2c9-4dae-b33a-7445bb6ca09a", "label": "a", "points": [[25.4, 61.5], [25.4, 470.7], [472.8, 470.7], [472.8, 61.5]], "color": "yellow"}, {"id": "75de5db2-6de9-4a32-969d-34850776fdd2", "label": "b", "points": [[491.9, 479.2], [491.9, 59.4], [954.1, 59.4], [954.1, 479.2]], "color": "cyan"}, {"id": "fd06b579-71d9-467c-a420-c38666ba9d39", "label": "c", "points": [[971, 59.4], [971, 462.2], [1323, 462.2], [1323, 59.4]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Preoperative", "start": 7, "end": 19, "id": 3}, {"text": "and", "start": 20, "end": 23, "id": 4}, {"text": "postoperative", "start": 24, "end": 37, "id": 5}, {"text": "images", "start": 38, "end": 44, "id": 6}, {"text": "of", "start": 45, "end": 47, "id": 7}, {"text": "one", "start": 48, "end": 51, "id": 8}, {"text": "patient", "start": 52, "end": 59, "id": 9}, {"text": "(", "start": 60, "end": 61, "id": 10}, {"text": "Case", "start": 61, "end": 65, "id": 11}, {"text": "No", "start": 66, "end": 68, "id": 12}, {"text": ".", "start": 68, "end": 69, "id": 13}, {"text": "9", "start": 70, "end": 71, "id": 14}, {"text": ")", "start": 71, "end": 72, "id": 15}, {"text": ".", "start": 72, "end": 73, "id": 16}, {"text": "a", "start": 74, "end": 75, "id": 17}, {"text": ":", "start": 75, "end": 76, "id": 18}, {"text": "Sagittal", "start": 77, "end": 85, "id": 19}, {"text": "preoperative", "start": 86, "end": 98, "id": 20}, {"text": "CT", "start": 99, "end": 101, "id": 21}, {"text": "showing", "start": 102, "end": 109, "id": 22}, {"text": "the", "start": 110, "end": 113, "id": 23}, {"text": "upper", "start": 114, "end": 119, "id": 24}, {"text": "tracheal", "start": 120, "end": 128, "id": 25}, {"text": "stenosis", "start": 129, "end": 137, "id": 26}, {"text": ".", "start": 137, "end": 138, "id": 27}, {"text": "b", "start": 139, "end": 140, "id": 28}, {"text": ":", "start": 140, "end": 141, "id": 29}, {"text": "Postoperative", "start": 142, "end": 155, "id": 30}, {"text": "sagittal", "start": 156, "end": 164, "id": 31}, {"text": "CT", "start": 165, "end": 167, "id": 32}, {"text": "showing", "start": 168, "end": 175, "id": 33}, {"text": "the", "start": 176, "end": 179, "id": 34}, {"text": "normal", "start": 180, "end": 186, "id": 35}, {"text": "trachea", "start": 187, "end": 194, "id": 36}, {"text": ".", "start": 194, "end": 195, "id": 37}, {"text": "c", "start": 196, "end": 197, "id": 38}, {"text": ":", "start": 197, "end": 198, "id": 39}, {"text": "The", "start": 199, "end": 202, "id": 40}, {"text": "appearance", "start": 203, "end": 213, "id": 41}, {"text": "of", "start": 214, "end": 216, "id": 42}, {"text": "the", "start": 217, "end": 220, "id": 43}, {"text": "suture", "start": 221, "end": 227, "id": 44}, {"text": "on", "start": 228, "end": 230, "id": 45}, {"text": "the", "start": 231, "end": 234, "id": 46}, {"text": "neck", "start": 235, "end": 239, "id": 47}]}
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{"pdf_hash": "cea8b356a0d02a796402ae2077fcc5eb18db1c69", "fig_key": "Figure3", "fig_uri": "18-Figure3-1.png", "text": "Fig. 3 AA-PET and MRI findings in a case of differential diagnosis between TML and breast cancer brain metastasis. 71 years old female patient previously treated for breast cancer who underwent ceMRI that showed the presence of a left frontal lesion hyperintense at T2 sequences (Panel a) and hypointense at T1 sequences (Panel b). 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{"pdf_hash": "257ad28a75b266248dfffaa6c3580c629f766b49", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Sagittal T2-weighted images of lumbo-sacral spine (A) and dorsolumba spine (B) show hyper-intense signal involving the D5, D6 and D12 vertebra with soft tissue component and sparing of IV discs which on post contrast scan (C) revealed heterogeneous enhancement in the body, posterior elements and epidural space with compressive myelopathy. Cytology revealed granuloma formation. A B C", "width": 638, "height": 390, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "b": [4, 5, 6, 7, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "c": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "9a202db3-6e51-434a-9c4f-60dd46b9a2ea", "label": "a", "points": [[1, 2.9], [1, 362.7], [210.7, 362.7], [210.7, 2.9]], "color": "yellow"}, {"id": "db4d3de1-a914-40b7-8a75-6ca66b0daec6", "label": "b", "points": [[219.8, 1.9], [219.8, 362.7], [424.4, 362.7], [424.4, 1.9]], "color": "cyan"}, {"id": "d01e8c9b-5339-4625-90ae-e019909e9fc2", "label": "c", "points": [[434.4, 0.8], [434.4, 362.7], [633, 362.7], [633, 0.8]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Sagittal", "start": 8, "end": 16, "id": 4}, {"text": "T2-weighted", "start": 17, "end": 28, "id": 5}, {"text": "images", "start": 29, "end": 35, "id": 6}, {"text": "of", "start": 36, "end": 38, "id": 7}, {"text": "lumbo", "start": 39, "end": 44, "id": 8}, {"text": "-", "start": 44, "end": 45, "id": 9}, {"text": "sacral", "start": 45, "end": 51, "id": 10}, {"text": "spine", "start": 52, "end": 57, "id": 11}, {"text": "(", "start": 58, "end": 59, "id": 12}, {"text": "A", "start": 59, "end": 60, "id": 13}, {"text": ")", "start": 60, "end": 61, "id": 14}, {"text": "and", "start": 62, "end": 65, "id": 15}, {"text": "dorsolumba", "start": 66, "end": 76, "id": 16}, {"text": "spine", "start": 77, "end": 82, "id": 17}, {"text": "(", "start": 83, "end": 84, "id": 18}, {"text": "B", "start": 84, "end": 85, "id": 19}, {"text": ")", "start": 85, "end": 86, "id": 20}, {"text": "show", "start": 87, "end": 91, "id": 21}, {"text": "hyper", "start": 92, "end": 97, "id": 22}, {"text": "-", "start": 97, "end": 98, "id": 23}, {"text": "intense", "start": 98, "end": 105, "id": 24}, {"text": "signal", "start": 106, "end": 112, "id": 25}, {"text": "involving", "start": 113, "end": 122, "id": 26}, {"text": "the", "start": 123, "end": 126, "id": 27}, {"text": "D5", "start": 127, "end": 129, "id": 28}, {"text": ",", "start": 129, "end": 130, "id": 29}, {"text": "D6", "start": 131, "end": 133, "id": 30}, {"text": "and", "start": 134, "end": 137, "id": 31}, {"text": "D12", "start": 138, "end": 141, "id": 32}, {"text": "vertebra", "start": 142, "end": 150, "id": 33}, {"text": "with", "start": 151, "end": 155, "id": 34}, {"text": "soft", "start": 156, "end": 160, "id": 35}, {"text": "tissue", "start": 161, "end": 167, "id": 36}, {"text": "component", "start": 168, "end": 177, "id": 37}, {"text": "and", "start": 178, "end": 181, "id": 38}, {"text": "sparing", "start": 182, "end": 189, "id": 39}, {"text": "of", "start": 190, "end": 192, "id": 40}, {"text": "IV", "start": 193, "end": 195, "id": 41}, {"text": "discs", "start": 196, "end": 201, "id": 42}, {"text": "which", "start": 202, "end": 207, "id": 43}, {"text": "on", "start": 208, "end": 210, "id": 44}, {"text": "post", "start": 211, "end": 215, "id": 45}, {"text": "contrast", "start": 216, "end": 224, "id": 46}, {"text": "scan", "start": 225, "end": 229, "id": 47}, {"text": "(", "start": 230, "end": 231, "id": 48}, {"text": "C", "start": 231, "end": 232, "id": 49}, {"text": ")", "start": 232, "end": 233, "id": 50}, {"text": "revealed", "start": 234, "end": 242, "id": 51}, {"text": "heterogeneous", "start": 243, "end": 256, "id": 52}, {"text": "enhancement", "start": 257, "end": 268, "id": 53}, {"text": "in", "start": 269, "end": 271, "id": 54}, {"text": "the", "start": 272, "end": 275, "id": 55}, {"text": "body", "start": 276, "end": 280, "id": 56}, {"text": ",", "start": 280, "end": 281, "id": 57}, {"text": "posterior", "start": 282, "end": 291, "id": 58}, {"text": "elements", "start": 292, "end": 300, "id": 59}, {"text": "and", "start": 301, "end": 304, "id": 60}, {"text": "epidural", "start": 305, "end": 313, "id": 61}, {"text": "space", "start": 314, "end": 319, "id": 62}, {"text": "with", "start": 320, "end": 324, "id": 63}, {"text": "compressive", "start": 325, "end": 336, "id": 64}, {"text": "myelopathy", "start": 337, "end": 347, "id": 65}, {"text": ".", "start": 347, "end": 348, "id": 66}, {"text": "Cytology", "start": 349, "end": 357, "id": 67}, {"text": "revealed", "start": 358, "end": 366, "id": 68}, {"text": "granuloma", "start": 367, "end": 376, "id": 69}, {"text": "formation", "start": 377, "end": 386, "id": 70}, {"text": ".", "start": 386, "end": 387, "id": 71}, {"text": "A", "start": 388, "end": 389, "id": 72}, {"text": "B", "start": 390, "end": 391, "id": 73}, {"text": "C", "start": 392, "end": 393, "id": 74}]}
{"pdf_hash": "11ce16fb0792b9b71d2df305ed00cb171f6a74b5", "fig_key": "Figure8", "fig_uri": "15-Figure8-1.png", "text": "Fig. 8 MRI 50 min after limb perfusion of an 11-week-old GRMD dog. T2-weighted TSE MR images without (a) and with (b, c) fat saturation. Composite images have been created to orient the left and right limbs in the same plane. As a result, some proximal structures such as the colon are duplicated. Craniocaudal (top) and transverse (bottom) sections proximal to the stifle are seen in a and b. In each image, the perfused limb is on the left. Increased signal intensity is consistently seen in the perfused limb. 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{"pdf_hash": "826e26e075f41d533fb5d2cba1f57159ed624bdb", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Endoscopic submucosal dissection of an esophageal leiomyoma using electrosurgical knife. (A) A large subepithelial tumor is observed at the lower esophagus. (B) The tumor is hypoechoic and located mainly in the submucosal layer on endoscopic ultrasonography. (C) After midline incision of overlying normal mucosa, a subepithelial tumor is exposed. (D) Submucosal dissection of the tumor is performed by using an IT-knife. (E) The lesion is completely removed. 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{"pdf_hash": "e5f7d14fa0710bb442ccdbe11c0cad9b924d68ae", "fig_key": "Figure5", "fig_uri": "3-Figure5-1.png", "text": "Fig. 5 A: Photograph of the solid and hard-elastic tumor. B-H: Photomicrographs showing perivascular lymphoid cell infiltration with nuclear atypia (hematoxylin and eosin stain, original magnifications B: \u00d7200, C: \u00d7400). The MIB-1 labeling index was 31% (D: original magnification \u00d7400). 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{"pdf_hash": "20a7679b83d4dbc1aa1a5280a271e7ffc8432409", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Figure 4. Transmission electron micrographs representative of MCF-7 cells. Confluent cells (60-70%) were treated with 6 \u00b5M of \u03b1-tomatine for 4 h. Images of transverse sections of the cells are shown. (A) Control cells, (B) \u03b1-tomatine-treated cells. The treated cells show disintegration of both the outer and nuclear membranes, but no typical morphologic signs of apoptosis.", "width": 1114, "height": 844, "subcaptions": {"a": [48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "98a17b5f-90f2-45a3-8e27-2307f0bb7fef", "label": "a", "points": [[47.8, 7.6], [47.8, 391.3], [551.2, 391.3], [551.2, 7.6]], "color": "yellow"}, {"id": "6bf90c0f-c5bd-4e3d-81b8-46599c192423", "label": "a", "points": [[591.6, 14.7], [591.6, 389.5], [1091.5, 389.5], [1091.5, 14.7]], "color": "cyan"}, {"id": "cc252f9a-6137-4e7d-8e7f-e797fb19007a", "label": "b", "points": [[42.5, 424.7], [42.5, 804.9], [551.2, 804.9], [551.2, 424.7]], "color": "magenta"}, {"id": "3ea3cdd2-e4b5-4bde-a47c-c8f92fb4f56b", "label": "b", "points": [[593.4, 426.5], [593.4, 810.2], [1093.2, 810.2], [1093.2, 426.5]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 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{"pdf_hash": "0dcf1dda2412aff21703d7662a268df35b349cac", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "Figure 6 Representative histological photomicrographs of coronal sections for two rats with bilateral tracks in the anterior VTA (a, b), and one with a unilateral track in the posterior VTA (c). Coronal typography was determined based on the rat brain atlas of Paxinos and Watson (1986).", "width": 644, "height": 1290, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "c": [32, 33, 34, 35, 36, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "b9a26923-429a-439d-bd6b-e294b03c9637", "label": "a", "points": [[30.6, 3.9], [30.6, 409.8], [603.3, 409.8], [603.3, 3.9]], "color": "yellow"}, {"id": "03f77979-2e80-4382-9ec7-7849c6013b67", "label": "b", "points": [[32.6, 443.4], [32.6, 845.2], [643, 845.2], [643, 443.4]], "color": "cyan"}, {"id": "49027a05-18ae-486a-8691-6fe149f097e3", "label": "c", "points": [[30.6, 883.9], [30.6, 1282.7], [642, 1282.7], [642, 883.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": "Representative", "start": 9, "end": 23, "id": 2}, {"text": "histological", "start": 24, "end": 36, "id": 3}, {"text": "photomicrographs", "start": 37, "end": 53, "id": 4}, {"text": "of", "start": 54, "end": 56, "id": 5}, {"text": "coronal", "start": 57, "end": 64, "id": 6}, {"text": "sections", "start": 65, "end": 73, "id": 7}, {"text": "for", "start": 74, "end": 77, "id": 8}, {"text": "two", "start": 78, "end": 81, "id": 9}, {"text": "rats", "start": 82, "end": 86, "id": 10}, {"text": "with", "start": 87, "end": 91, "id": 11}, {"text": "bilateral", "start": 92, "end": 101, "id": 12}, {"text": "tracks", "start": 102, "end": 108, "id": 13}, {"text": "in", "start": 109, "end": 111, "id": 14}, {"text": "the", "start": 112, "end": 115, "id": 15}, {"text": "anterior", "start": 116, "end": 124, "id": 16}, {"text": "VTA", "start": 125, "end": 128, "id": 17}, {"text": "(", "start": 129, "end": 130, "id": 18}, {"text": "a", "start": 130, "end": 131, "id": 19}, {"text": ",", "start": 131, "end": 132, "id": 20}, {"text": "b", "start": 133, "end": 134, "id": 21}, {"text": ")", "start": 134, "end": 135, "id": 22}, {"text": ",", "start": 135, "end": 136, "id": 23}, {"text": "and", "start": 137, "end": 140, "id": 24}, {"text": "one", "start": 141, "end": 144, "id": 25}, {"text": "with", "start": 145, "end": 149, "id": 26}, {"text": "a", "start": 150, "end": 151, "id": 27}, {"text": "unilateral", "start": 152, "end": 162, "id": 28}, {"text": "track", "start": 163, "end": 168, "id": 29}, {"text": "in", "start": 169, "end": 171, "id": 30}, {"text": "the", "start": 172, "end": 175, "id": 31}, {"text": "posterior", "start": 176, "end": 185, "id": 32}, {"text": "VTA", "start": 186, "end": 189, "id": 33}, {"text": "(", "start": 190, "end": 191, "id": 34}, {"text": "c", "start": 191, "end": 192, "id": 35}, {"text": ")", "start": 192, "end": 193, "id": 36}, {"text": ".", "start": 193, "end": 194, "id": 37}, {"text": "Coronal", "start": 195, "end": 202, "id": 38}, {"text": "typography", "start": 203, "end": 213, "id": 39}, {"text": "was", "start": 214, "end": 217, "id": 40}, {"text": "determined", "start": 218, "end": 228, "id": 41}, {"text": "based", "start": 229, "end": 234, "id": 42}, {"text": "on", "start": 235, "end": 237, "id": 43}, {"text": "the", "start": 238, "end": 241, "id": 44}, {"text": "rat", "start": 242, "end": 245, "id": 45}, {"text": "brain", "start": 246, "end": 251, "id": 46}, {"text": "atlas", "start": 252, "end": 257, "id": 47}, {"text": "of", "start": 258, "end": 260, "id": 48}, {"text": "Paxinos", "start": 261, "end": 268, "id": 49}, {"text": "and", "start": 269, "end": 272, "id": 50}, {"text": "Watson", "start": 273, "end": 279, "id": 51}, {"text": "(", "start": 280, "end": 281, "id": 52}, {"text": "1986", "start": 281, "end": 285, "id": 53}, {"text": ")", "start": 285, "end": 286, "id": 54}, {"text": ".", "start": 286, "end": 287, "id": 55}]}
{"pdf_hash": "fd5dbc4b1d5b5b80365728f9dd13184d9206a49d", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Hematoxylin and Eosin stain of tongue scar at 5 weeks. Axial cuts, perpendicular to the long axis of the tongue demonstrating (A) low power (4x) and (B) high power (20x) H&E stain of the contralateral uninjured hemi tongue. (C) Low power (4x) and (D) high power (20x) H&E stain of the ipsilateral injured hemi tongue. (C) and (D) illustrate dense stromal fibrosis, lymphocytic infiltrate, and loss of a significant portion of the intrinsic muscular architecture of the tongue. 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{"pdf_hash": "a8c091ffb11de470156b5cdb7864b9cdb81d2574", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Twelve right-sided and midline landmarks located on 3D CT reconstructions (lateral view at left; ectocranial base at right) used in analysis. Landmark names are given in Table 2. *Sella (sel) is located endocranially, but its approximate location is shown on the ectocranial view.", "width": 698, "height": 378, "subcaptions": {"a": [17, 18, 19, 20, 21], "b": [22, 23, 24, 25]}, "subfigures": [{"id": "845d7924-285d-41c4-a86c-d7bd0335d6e3", "label": "a", "points": [[4.6, 2.6], [4.6, 349.9], [397.2, 349.9], [397.2, 2.6]], "color": "yellow"}, {"id": "5874b2f5-d454-48f5-8e9e-481e20a2c6fc", "label": "b", "points": [[408.2, 3.7], [408.2, 348.8], [694.9, 348.8], [694.9, 3.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Twelve", "start": 8, "end": 14, "id": 4}, {"text": "right", "start": 15, "end": 20, "id": 5}, {"text": "-", "start": 20, "end": 21, "id": 6}, {"text": "sided", "start": 21, "end": 26, "id": 7}, {"text": "and", "start": 27, "end": 30, "id": 8}, {"text": "midline", "start": 31, "end": 38, "id": 9}, {"text": "landmarks", "start": 39, "end": 48, "id": 10}, {"text": "located", "start": 49, "end": 56, "id": 11}, {"text": "on", "start": 57, "end": 59, "id": 12}, {"text": "3D", "start": 60, "end": 62, "id": 13}, {"text": "CT", "start": 63, "end": 65, "id": 14}, {"text": "reconstructions", "start": 66, "end": 81, "id": 15}, {"text": "(", "start": 82, "end": 83, "id": 16}, {"text": "lateral", "start": 83, "end": 90, "id": 17}, {"text": "view", "start": 91, "end": 95, "id": 18}, {"text": "at", "start": 96, "end": 98, "id": 19}, {"text": "left", "start": 99, "end": 103, "id": 20}, {"text": ";", "start": 103, "end": 104, "id": 21}, {"text": "ectocranial", "start": 105, "end": 116, "id": 22}, {"text": "base", "start": 117, "end": 121, "id": 23}, {"text": "at", "start": 122, "end": 124, "id": 24}, {"text": "right", "start": 125, "end": 130, "id": 25}, {"text": ")", "start": 130, "end": 131, "id": 26}, {"text": "used", "start": 132, "end": 136, "id": 27}, {"text": "in", "start": 137, "end": 139, "id": 28}, {"text": "analysis", "start": 140, "end": 148, "id": 29}, {"text": ".", "start": 148, "end": 149, "id": 30}, {"text": "Landmark", "start": 150, "end": 158, "id": 31}, {"text": "names", "start": 159, "end": 164, "id": 32}, {"text": "are", "start": 165, "end": 168, "id": 33}, {"text": "given", "start": 169, "end": 174, "id": 34}, {"text": "in", "start": 175, "end": 177, "id": 35}, {"text": "Table", "start": 178, "end": 183, "id": 36}, {"text": "2", "start": 184, "end": 185, "id": 37}, {"text": ".", "start": 185, "end": 186, "id": 38}, {"text": "*", "start": 187, "end": 188, "id": 39}, {"text": "Sella", "start": 188, "end": 193, "id": 40}, {"text": "(", "start": 194, "end": 195, "id": 41}, {"text": "sel", "start": 195, "end": 198, "id": 42}, {"text": ")", "start": 198, "end": 199, "id": 43}, {"text": "is", "start": 200, "end": 202, "id": 44}, {"text": "located", "start": 203, "end": 210, "id": 45}, {"text": "endocranially", "start": 211, "end": 224, "id": 46}, {"text": ",", "start": 224, "end": 225, "id": 47}, {"text": "but", "start": 226, "end": 229, "id": 48}, {"text": "its", "start": 230, "end": 233, "id": 49}, {"text": "approximate", "start": 234, "end": 245, "id": 50}, {"text": "location", "start": 246, "end": 254, "id": 51}, {"text": "is", "start": 255, "end": 257, "id": 52}, {"text": "shown", "start": 258, "end": 263, "id": 53}, {"text": "on", "start": 264, "end": 266, "id": 54}, {"text": "the", "start": 267, "end": 270, "id": 55}, {"text": "ectocranial", "start": 271, "end": 282, "id": 56}, {"text": "view", "start": 283, "end": 287, "id": 57}, {"text": ".", "start": 287, "end": 288, "id": 58}]}
{"pdf_hash": "261030a3a7c6391cd1f6fd0ad1a00bce89c47d40", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2: Magnetic resonance angiography suggested left vertebral artery hypoplasia (VAH) (a, arrow). High resolution magnetic resonance images with coronal (b, arrow) and axil (c, arrow) reconstructed image showed slim lumen with normal wall. This case was finally diagnosed as VAH with normal wall.", "width": 562, "height": 522, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 39, 40, 41, 42, 43, 44, 45, 46, 47], "c": [20, 21, 22, 23, 24, 25, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "196f2d92-3d26-474d-bd47-1618716ffe25", "label": "a", "points": [[36, 0.7], [36, 244.7], [283, 244.7], [283, 0.7]], "color": "yellow"}, {"id": "6c91a6bb-fba2-4946-8875-a165fa23603d", "label": "b", "points": [[286, 0.7], [286, 241.7], [528, 241.7], [528, 0.7]], "color": "cyan"}, {"id": "57e62661-6da8-4977-8b85-ffb35994cc21", "label": "c", "points": [[154, 248.7], [154, 486.7], [406, 486.7], [406, 248.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Magnetic", "start": 10, "end": 18, "id": 3}, {"text": "resonance", "start": 19, "end": 28, "id": 4}, {"text": "angiography", "start": 29, "end": 40, "id": 5}, {"text": "suggested", "start": 41, "end": 50, "id": 6}, {"text": "left", "start": 51, "end": 55, "id": 7}, {"text": "vertebral", "start": 56, "end": 65, "id": 8}, {"text": "artery", "start": 66, "end": 72, "id": 9}, {"text": "hypoplasia", "start": 73, "end": 83, "id": 10}, {"text": "(", "start": 84, "end": 85, "id": 11}, {"text": "VAH", "start": 85, "end": 88, "id": 12}, {"text": ")", "start": 88, "end": 89, "id": 13}, {"text": "(", "start": 90, "end": 91, "id": 14}, {"text": "a", "start": 91, "end": 92, "id": 15}, {"text": ",", "start": 92, "end": 93, "id": 16}, {"text": "arrow", "start": 94, "end": 99, "id": 17}, {"text": ")", "start": 99, "end": 100, "id": 18}, {"text": ".", "start": 100, "end": 101, "id": 19}, {"text": "High", "start": 102, "end": 106, "id": 20}, {"text": "resolution", "start": 107, "end": 117, "id": 21}, {"text": "magnetic", "start": 118, "end": 126, "id": 22}, {"text": "resonance", "start": 127, "end": 136, "id": 23}, {"text": "images", "start": 137, "end": 143, "id": 24}, {"text": "with", "start": 144, "end": 148, "id": 25}, {"text": "coronal", "start": 149, "end": 156, "id": 26}, {"text": "(", "start": 157, "end": 158, "id": 27}, {"text": "b", "start": 158, "end": 159, "id": 28}, {"text": ",", "start": 159, "end": 160, "id": 29}, {"text": "arrow", "start": 161, "end": 166, "id": 30}, {"text": ")", "start": 166, "end": 167, "id": 31}, {"text": "and", "start": 168, "end": 171, "id": 32}, {"text": "axil", "start": 172, "end": 176, "id": 33}, {"text": "(", "start": 177, "end": 178, "id": 34}, {"text": "c", "start": 178, "end": 179, "id": 35}, {"text": ",", "start": 179, "end": 180, "id": 36}, {"text": "arrow", "start": 181, "end": 186, "id": 37}, {"text": ")", "start": 186, "end": 187, "id": 38}, {"text": "reconstructed", "start": 188, "end": 201, "id": 39}, {"text": "image", "start": 202, "end": 207, "id": 40}, {"text": "showed", "start": 208, "end": 214, "id": 41}, {"text": "slim", "start": 215, "end": 219, "id": 42}, {"text": "lumen", "start": 220, "end": 225, "id": 43}, {"text": "with", "start": 226, "end": 230, "id": 44}, {"text": "normal", "start": 231, "end": 237, "id": 45}, {"text": "wall", "start": 238, "end": 242, "id": 46}, {"text": ".", "start": 242, "end": 243, "id": 47}, {"text": "This", "start": 244, "end": 248, "id": 48}, {"text": "case", "start": 249, "end": 253, "id": 49}, {"text": "was", "start": 254, "end": 257, "id": 50}, {"text": "finally", "start": 258, "end": 265, "id": 51}, {"text": "diagnosed", "start": 266, "end": 275, "id": 52}, {"text": "as", "start": 276, "end": 278, "id": 53}, {"text": "VAH", "start": 279, "end": 282, "id": 54}, {"text": "with", "start": 283, "end": 287, "id": 55}, {"text": "normal", "start": 288, "end": 294, "id": 56}, {"text": "wall", "start": 295, "end": 299, "id": 57}, {"text": ".", "start": 299, "end": 300, "id": 58}]}
{"pdf_hash": "083850084d086cb7846ebdea0e32cbe183f5639b", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. fMRI images of priming. The images in the upper row are fMRI data (coloured scale, with brighter colours indicating larger signal change) displayed on top of anatomical images. Images are from horizontal sections through the brain. The images below the fMRI data are a schematic representation of the comparison being imaged. (a) fMRI data show brain areas activated by an object classi\u00a2cation task (for both novel and repeated items) compared with a low-level \u00a2xation control task, collapsing over both novel and repeated items, revealing the network of brain areas activated in common by both item types. These include the left dorsal frontal (LDF) cortex and visual areas. 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{"pdf_hash": "c633f29514cd34c64ff9c7a69266be475323611c", "fig_key": "Figure14", "fig_uri": "12-Figure14-1.png", "text": "FIG. 14. Dynamic susceptibility contrast imaging. a: Time course of the T2*-weighted MR images during contrast material bolus passage. Due to the high concentration of contrast material the signal intensity decreases significantly during the peak of the bolus. b: The corresponding concentration time course demonstrates highest signal intensities during the peak of the bolus passage.", "width": 1062, "height": 896, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "b": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "e9142ba5-2a3d-482c-839c-69d19fe34505", "label": "a", "points": [[40.5, 0], [40.5, 424.5], [1025.4, 424.5], [1025.4, 0]], "color": "yellow"}, {"id": "728b67d9-4afd-48e5-8136-79dd2342675d", "label": "b", "points": [[40.5, 442.9], [40.5, 870.8], [1028.8, 870.8], [1028.8, 442.9]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "14", "start": 5, "end": 7, "id": 2}, {"text": ".", "start": 7, "end": 8, "id": 3}, {"text": "Dynamic", "start": 9, "end": 16, "id": 4}, {"text": "susceptibility", "start": 17, "end": 31, "id": 5}, {"text": "contrast", "start": 32, "end": 40, "id": 6}, {"text": "imaging", "start": 41, "end": 48, "id": 7}, {"text": ".", "start": 48, "end": 49, "id": 8}, {"text": "a", "start": 50, "end": 51, "id": 9}, {"text": ":", "start": 51, "end": 52, "id": 10}, {"text": "Time", "start": 53, "end": 57, "id": 11}, {"text": "course", "start": 58, "end": 64, "id": 12}, {"text": "of", "start": 65, "end": 67, "id": 13}, {"text": "the", "start": 68, "end": 71, "id": 14}, {"text": "T2", "start": 72, "end": 74, "id": 15}, {"text": "*", "start": 74, "end": 75, "id": 16}, {"text": "-weighted", "start": 75, "end": 84, "id": 17}, {"text": "MR", "start": 85, "end": 87, "id": 18}, {"text": "images", "start": 88, "end": 94, "id": 19}, {"text": "during", "start": 95, "end": 101, "id": 20}, {"text": "contrast", "start": 102, "end": 110, "id": 21}, {"text": "material", "start": 111, "end": 119, "id": 22}, {"text": "bolus", "start": 120, "end": 125, "id": 23}, {"text": "passage", "start": 126, "end": 133, "id": 24}, {"text": ".", "start": 133, "end": 134, "id": 25}, {"text": "Due", "start": 135, "end": 138, "id": 26}, {"text": "to", "start": 139, "end": 141, "id": 27}, {"text": "the", "start": 142, "end": 145, "id": 28}, {"text": "high", "start": 146, "end": 150, "id": 29}, {"text": "concentration", "start": 151, "end": 164, "id": 30}, {"text": "of", "start": 165, "end": 167, "id": 31}, {"text": "contrast", "start": 168, "end": 176, "id": 32}, {"text": "material", "start": 177, "end": 185, "id": 33}, {"text": "the", "start": 186, "end": 189, "id": 34}, {"text": "signal", "start": 190, "end": 196, "id": 35}, {"text": "intensity", "start": 197, "end": 206, "id": 36}, {"text": "decreases", "start": 207, "end": 216, "id": 37}, {"text": "significantly", "start": 217, "end": 230, "id": 38}, {"text": "during", "start": 231, "end": 237, "id": 39}, {"text": "the", "start": 238, "end": 241, "id": 40}, {"text": "peak", "start": 242, "end": 246, "id": 41}, {"text": "of", "start": 247, "end": 249, "id": 42}, {"text": "the", "start": 250, "end": 253, "id": 43}, {"text": "bolus", "start": 254, "end": 259, "id": 44}, {"text": ".", "start": 259, "end": 260, "id": 45}, {"text": "b", "start": 261, "end": 262, "id": 46}, {"text": ":", "start": 262, "end": 263, "id": 47}, {"text": "The", "start": 264, "end": 267, "id": 48}, {"text": "corresponding", "start": 268, "end": 281, "id": 49}, {"text": "concentration", "start": 282, "end": 295, "id": 50}, {"text": "time", "start": 296, "end": 300, "id": 51}, {"text": "course", "start": 301, "end": 307, "id": 52}, {"text": "demonstrates", "start": 308, "end": 320, "id": 53}, {"text": "highest", "start": 321, "end": 328, "id": 54}, {"text": "signal", "start": 329, "end": 335, "id": 55}, {"text": "intensities", "start": 336, "end": 347, "id": 56}, {"text": "during", "start": 348, "end": 354, "id": 57}, {"text": "the", "start": 355, "end": 358, "id": 58}, {"text": "peak", "start": 359, "end": 363, "id": 59}, {"text": "of", "start": 364, "end": 366, "id": 60}, {"text": "the", "start": 367, "end": 370, "id": 61}, {"text": "bolus", "start": 371, "end": 376, "id": 62}, {"text": "passage", "start": 377, "end": 384, "id": 63}, {"text": ".", "start": 384, "end": 385, "id": 64}]}
{"pdf_hash": "97d454f9e1a5edb02d86d7c1c8fed9f9d175afd3", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4 The nidus and inflammatory response in the surrounding tissues are evident on the coronal T2-weighted (a) and transverse T1-weighted (b) MRIs", "width": 712, "height": 992, "subcaptions": {"a": [16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26]}, "subfigures": [{"id": "550e4481-2776-4b7c-9d6c-549c38247b68", "label": "a", "points": [[7.9, 0], [7.9, 493.8], [676, 493.8], [676, 0]], "color": "yellow"}, {"id": "eef47889-f0c8-4413-974a-16100f4d5a63", "label": "b", "points": [[5.6, 501.7], [5.6, 991], [679.4, 991], [679.4, 501.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "The", "start": 7, "end": 10, "id": 3}, {"text": "nidus", "start": 11, "end": 16, "id": 4}, {"text": "and", "start": 17, "end": 20, "id": 5}, {"text": "inflammatory", "start": 21, "end": 33, "id": 6}, {"text": "response", "start": 34, "end": 42, "id": 7}, {"text": "in", "start": 43, "end": 45, "id": 8}, {"text": "the", "start": 46, "end": 49, "id": 9}, {"text": "surrounding", "start": 50, "end": 61, "id": 10}, {"text": "tissues", "start": 62, "end": 69, "id": 11}, {"text": "are", "start": 70, "end": 73, "id": 12}, {"text": "evident", "start": 74, "end": 81, "id": 13}, {"text": "on", "start": 82, "end": 84, "id": 14}, {"text": "the", "start": 85, "end": 88, "id": 15}, {"text": "coronal", "start": 89, "end": 96, "id": 16}, {"text": "T2-weighted", "start": 97, "end": 108, "id": 17}, {"text": "(", "start": 109, "end": 110, "id": 18}, {"text": "a", "start": 110, "end": 111, "id": 19}, {"text": ")", "start": 111, "end": 112, "id": 20}, {"text": "and", "start": 113, "end": 116, "id": 21}, {"text": "transverse", "start": 117, "end": 127, "id": 22}, {"text": "T1-weighted", "start": 128, "end": 139, "id": 23}, {"text": "(", "start": 140, "end": 141, "id": 24}, {"text": "b", "start": 141, "end": 142, "id": 25}, {"text": ")", "start": 142, "end": 143, "id": 26}, {"text": "MRIs", "start": 144, "end": 148, "id": 27}]}
{"pdf_hash": "8ce9c1c98daff17a47aac877f77b5305e433c1a9", "fig_key": "Figure13", "fig_uri": "7-Figure13-1.png", "text": "Figure 13 MRI view of the anterior (at the bottom) and posterior (at the top) meniscofemoral ligament.", "width": 554, "height": 586, "subcaptions": {"a": [13, 14, 15, 16, 17, 18], "b": [13, 14, 15, 16, 17, 18], "c": [6, 7, 8, 9, 10, 11], "d": [6, 7, 8, 9, 10, 11]}, "subfigures": [{"id": "92322b44-f606-4097-86c8-b4952aae0eb0", "label": "a", "points": [[0.7, 0.3], [0.7, 270.3], [263.7, 270.3], [263.7, 0.3]], "color": "yellow"}, {"id": "52d1b666-1ba8-42ee-ae24-da7ac8c66dc0", "label": "b", "points": [[279.7, 5.3], [279.7, 294.3], [545.7, 294.3], [545.7, 5.3]], "color": "cyan"}, {"id": "e3d3957b-2f12-4650-aa05-e23898e09a49", "label": "c", "points": [[3.7, 282.3], [3.7, 554.3], [268.7, 554.3], [268.7, 282.3]], "color": "magenta"}, {"id": "c6d5e90d-75b0-4640-ae91-0489bb60d9c7", "label": "d", "points": [[287.7, 314.3], [287.7, 553.3], [549.7, 553.3], [549.7, 314.3]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "13", "start": 7, "end": 9, "id": 1}, {"text": "MRI", "start": 10, "end": 13, "id": 2}, {"text": "view", "start": 14, "end": 18, "id": 3}, {"text": "of", "start": 19, "end": 21, "id": 4}, {"text": "the", "start": 22, "end": 25, "id": 5}, {"text": "anterior", "start": 26, "end": 34, "id": 6}, {"text": "(", "start": 35, "end": 36, "id": 7}, {"text": "at", "start": 36, "end": 38, "id": 8}, {"text": "the", "start": 39, "end": 42, "id": 9}, {"text": "bottom", "start": 43, "end": 49, "id": 10}, {"text": ")", "start": 49, "end": 50, "id": 11}, {"text": "and", "start": 51, "end": 54, "id": 12}, {"text": "posterior", "start": 55, "end": 64, "id": 13}, {"text": "(", "start": 65, "end": 66, "id": 14}, {"text": "at", "start": 66, "end": 68, "id": 15}, {"text": "the", "start": 69, "end": 72, "id": 16}, {"text": "top", "start": 73, "end": 76, "id": 17}, {"text": ")", "start": 76, "end": 77, "id": 18}, {"text": "meniscofemoral", "start": 78, "end": 92, "id": 19}, {"text": "ligament", "start": 93, "end": 101, "id": 20}, {"text": ".", "start": 101, "end": 102, "id": 21}]}
{"pdf_hash": "40a5230582928a7a730dc248c6ee86c76843e29d", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. Axillary ultrasound. a: lymph node with benign appearance retaining a fine cortex and an echogenic hilum; b: suspect lymph node showing irregular eccentric thickening of the cortex while the fatty hilum is conserved; c: very suspect lymph node, of increased thickness, with very thick cortex and virtual disappearance of the fatty hilum; d: Round, totally hypoechoic lymph node with metastatic appearance.", "width": 1376, "height": 1072, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "c": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62], "d": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75]}, "subfigures": [{"id": "4a4ab067-b4e8-4992-ac3f-36f1f574cbfe", "label": "a", "points": [[29.4, 4], [29.4, 486.5], [677.2, 486.5], [677.2, 4]], "color": "yellow"}, {"id": "f379eda9-e6f6-4419-8cfa-6fa13f0495f5", "label": "b", "points": [[696.8, 1.8], 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{"pdf_hash": "d108e46c6e5ffd7613ca30ddbaeeaf85347501c0", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 The intraoperative images of a 68-year-old man who underwent RF-TR by the use of the intraoperative CT with MRI fusion-guided technique. The trajectory (green line) was chosen along an unobstructed linear pathway to penetrate foramen ovale (purple circle) into the trigeminal cistern (green circle). The lateral pterygoid plate (yellow line) should be avoided during penetration. Three-dimentional skin probe eye view (a), inline sagittal view (b), inline axial view (c), and probe eye view (d)", "width": 866, "height": 854, "subcaptions": {"a": [75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85], "b": [86, 87, 88, 89, 90, 91, 92], "c": [93, 94, 95, 96, 97, 98, 99], "d": [100, 101, 102, 103, 104, 105, 106]}, "subfigures": [{"id": "6d858bd4-b22c-4fea-9f6f-8eace34c1894", "label": "a", "points": [[7.5, 6.8], [7.5, 417.3], [427.5, 417.3], [427.5, 6.8]], "color": "yellow"}, {"id": "a9d00170-3b10-409a-9a06-a7635f8e4784", "label": "b", "points": [[437.1, 4.1], [437.1, 417.3], [855.8, 417.3], [855.8, 4.1]], "color": "cyan"}, {"id": "a50fd198-64af-49eb-851c-f154dbb31a4b", "label": "c", "points": [[6.2, 432.3], [6.2, 840], [422.1, 840], [422.1, 432.3]], "color": "magenta"}, {"id": "6433582a-e3dd-42bb-b8f2-fc12f87142e7", "label": "d", "points": [[438.5, 429.6], [438.5, 845.5], [855.8, 845.5], [855.8, 429.6]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 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{"pdf_hash": "0fce3d89e754e21e6565f481e1219f887190a644", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1. (a) Metallic coils retention (arrow) in the left middle lung zone in chest X-ray. (b) EGD revealed gastric telangiectases with vessel-pulled appearance.", "width": 1010, "height": 446, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36]}, "subfigures": [{"id": "658bdbd0-6bed-4ed5-917d-3aa94774ceb6", "label": "a", "points": [[34.4, 6.1], [34.4, 401.8], [498.7, 401.8], [498.7, 6.1]], "color": "yellow"}, {"id": "4a300aad-8bac-4808-903e-60f23185aa2a", "label": "b", "points": [[508.2, 10.9], [508.2, 409.8], [974.1, 409.8], [974.1, 10.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Metallic", "start": 14, "end": 22, "id": 6}, {"text": "coils", "start": 23, "end": 28, "id": 7}, {"text": "retention", "start": 29, "end": 38, "id": 8}, {"text": "(", "start": 39, "end": 40, "id": 9}, {"text": "arrow", "start": 40, "end": 45, "id": 10}, {"text": ")", "start": 45, "end": 46, "id": 11}, {"text": "in", "start": 47, "end": 49, "id": 12}, {"text": "the", "start": 50, "end": 53, "id": 13}, {"text": "left", "start": 54, "end": 58, "id": 14}, {"text": "middle", "start": 59, "end": 65, "id": 15}, {"text": "lung", "start": 66, "end": 70, "id": 16}, {"text": "zone", "start": 71, "end": 75, "id": 17}, {"text": "in", "start": 76, "end": 78, "id": 18}, {"text": "chest", "start": 79, "end": 84, "id": 19}, {"text": "X", "start": 85, "end": 86, "id": 20}, {"text": "-", "start": 86, "end": 87, "id": 21}, {"text": "ray", "start": 87, "end": 90, "id": 22}, {"text": ".", "start": 90, "end": 91, "id": 23}, {"text": "(", "start": 92, "end": 93, "id": 24}, {"text": "b", "start": 93, "end": 94, "id": 25}, {"text": ")", "start": 94, "end": 95, "id": 26}, {"text": "EGD", "start": 96, "end": 99, "id": 27}, {"text": "revealed", "start": 100, "end": 108, "id": 28}, {"text": "gastric", "start": 109, "end": 116, "id": 29}, {"text": "telangiectases", "start": 117, "end": 131, "id": 30}, {"text": "with", "start": 132, "end": 136, "id": 31}, {"text": "vessel", "start": 137, "end": 143, "id": 32}, {"text": "-", "start": 143, "end": 144, "id": 33}, {"text": "pulled", "start": 144, "end": 150, "id": 34}, {"text": "appearance", "start": 151, "end": 161, "id": 35}, {"text": ".", "start": 161, "end": 162, "id": 36}]}
{"pdf_hash": "fd167d8e11a98f7a8a899f161295fd06d791ad49", "fig_key": "Figure9", "fig_uri": "7-Figure9-1.png", "text": "Fig. 9 Posttraumatic unstable osteochondral lesion of the talus and massive degenerative changes of the ankle in a 66-year-old female. a. CR (AP view) demonstrating the presence of metallic screw within the fibula (arrow). Note irregular articular surface of talar dome and advanced degenerative changes with osteophytes formation (arrowheads). b. CBCT coronal reformatted image better shows the presence and extent of an unstable osteochondral lesion (arrow) and osteophytes (arrowheads). There is no metal artifact from the screw in the fibula", "width": 578, "height": 1178, "subcaptions": {"a": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "b": [61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85]}, "subfigures": [{"id": "8c5e7ab6-c4d0-46c8-afd7-28261dd077f9", "label": "a", "points": [[38.5, 28.8], [38.5, 640.9], [541.5, 640.9], [541.5, 28.8]], "color": "yellow"}, {"id": "edb3c5e4-d118-4b79-8167-ac05e4d378fc", "label": "b", "points": [[40.5, 661.4], [40.5, 1150.4], [543.5, 1150.4], [543.5, 661.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "9", "start": 5, "end": 6, "id": 2}, {"text": "Posttraumatic", "start": 7, "end": 20, "id": 3}, {"text": "unstable", "start": 21, "end": 29, "id": 4}, {"text": "osteochondral", "start": 30, 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{"pdf_hash": "b2b1415d7b4c75e954d725faa1379a3b6101f5d8", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Lipid-rich adenoma in a 66-year-old woman. Transverse, T1-weighted in-phase (A, TR/TE of 125/4.3 ms, 80\u00b0 flip angle) and out-of-phase (B, TR/TE of 125/ 2.1 ms, 80\u00b0 flip angle) images of a right adrenal nodule that showed a signal drop in the out-of-phase sequence. The adrenal index was 69%. 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{"pdf_hash": "3f81cff7fe6bd5e44533e2fee883c51243a892eb", "fig_key": "Figure4", "fig_uri": "2-Figure4-1.png", "text": "Fig. 4 Post-operative followup chest x-ray day-5 and day-15", "width": 1018, "height": 642, "subcaptions": {"a": [11], "b": [13]}, "subfigures": [{"id": "9b1f41e4-fad1-4f47-9752-5fd80805d998", "label": "a", "points": [[7.3, 3], [7.3, 635], [468.8, 635], [468.8, 3]], "color": "yellow"}, {"id": "d17d8fb8-f027-46ce-ab96-6a3e44c84bc5", "label": "b", "points": [[484.9, 6.2], [484.9, 635], [1010.8, 635], [1010.8, 6.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "Post", "start": 7, "end": 11, "id": 3}, {"text": "-", "start": 11, "end": 12, "id": 4}, {"text": "operative", "start": 12, "end": 21, "id": 5}, {"text": "followup", "start": 22, "end": 30, "id": 6}, {"text": "chest", "start": 31, "end": 36, "id": 7}, {"text": "x", "start": 37, "end": 38, "id": 8}, {"text": "-", "start": 38, "end": 39, "id": 9}, {"text": "ray", "start": 39, "end": 42, "id": 10}, {"text": "day-5", "start": 43, "end": 48, "id": 11}, {"text": "and", "start": 49, "end": 52, "id": 12}, {"text": "day-15", "start": 53, "end": 59, "id": 13}]}
{"pdf_hash": "f54176f1bc0c973d43641cf0399dfc710e7dddaa", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4 Sagittal and axial T2 WIs (a and b) show a large epidural and posterior paraspinal fluid collection in a patient with L4\u20135 decompression and fusion. Postcontrast image (c) shows no significant enhancement around the collection. The patient had orthostatic headaches and MRI brain confirmed dural thickening and effusion on FLAIR (d) with diffuse pachymeningeal enhancement (e) consistent with intracranial hypotension due to CSF leak and psedomeningocele formation", "width": 1370, "height": 390, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 31], "d": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79], "e": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79]}, "subfigures": [{"id": "c8e1f608-e41e-4fb8-a07d-fb1e325f6334", "label": "a", "points": [[8.4, 37], [8.4, 359.4], [224.8, 359.4], [224.8, 37]], "color": "yellow"}, {"id": 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{"pdf_hash": "50402d4917aa717fe172f8803fb001b5fff62549", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Figure 1: Example of densitometric quantification of adipose tissue area (threshold: -190 to -30 HU) in a CT scan at level L3/4: ROI determining TAT (a) and VAT (b). Example of densitometric quantification of muscle area in a CT-scan at level L 3/4 with ROI determining muscle compartments with threshold: -29 to +150 HU (c) and IMFA with threshold: -190 to-30HU (d).", "width": 1384, "height": 1234, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 34, 35, 36, 37], "c": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69], "d": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80]}, "subfigures": [{"id": "1b0a3d86-b0c0-4a54-ad45-c5ddbe4c7974", "label": "a", "points": [[3.3, 35], [3.3, 607.8], [639.5, 607.8], [639.5, 35]], "color": "yellow"}, {"id": "42ffbeec-54ae-4f3a-b68b-13eb8f0b8e46", "label": "b", "points": [[751, 43.7], [751, 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{"pdf_hash": "d7f24ff810b1798462833ee0db3f8f106b2cc60e", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. A 61-year-old man with benign solitary pulmonary nodule. A, Axial T1-weighted FFE and B, T2-weighted TSE MR images show a nodule in the right lower lobe of the lung. C, This nodule (arrow) shows peripheral ring-enhancement on the axial post contrast fat-suppressed T1-weighted image (5th minute). D, SI-time curve and quantitative interpretation of the curve obtained from the nodule. 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{"pdf_hash": "91d4201d749f8570c0d9023433f2b9fd21b3d3fd", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Complete response of hepatocellular carcinoma treated with radiofrequency ablation. Pre-treatment CT obtained in the arterial (a) and the delayed phase (b) shows the lesion as a small hypervascular nodule (a). Injection of an ultrasound contrast agent confirms arterial-phase enhancing tumour (arrow, c). B-mode low-mechanical index image is shown in the left side of the image; the contrast-specific mode during the arterial phase is shown in the right side. The tumour is treated with RF ablation under US guidance. At the end of the procedure, a large hyperechoic cloud covering the tumour as well as a cuff of surrounding liver parenchyma is seen on US (d). Contrast-enhanced ultrasound study performed at the end of the procedure shows the ablation zone as an unenhanced area completely covering the tumour. Peri-ablation enhancement is also seen, representing reactive hyperaemia (e). On CT images obtained in the arterial (f) and the portal venous phase (g) 1 month after treatment, the tumour is replaced by a non-enhancing ablation zone. 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{"pdf_hash": "edf078ce084f7383d49ea3569723b03435a7e062", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "FIG. 4. STM images 300 300 nm2 showing rapid decay of adatom islands while S increases to 35 mML: a island distribution before exposure to S, b imaging during S exposure, which starts at the bottom as indicated by a lower arrow and which is completed at the top arrow. We also indicate the change in size in nm2 of two selected islands near the bottom of the images.", "width": 652, "height": 288, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75]}, "subfigures": [{"id": "c337ffd7-dfbd-48be-a6cb-979187bd27cb", "label": "a", "points": [[5.7, 9.3], [5.7, 278.1], [276.6, 278.1], [276.6, 9.3]], "color": "yellow"}, {"id": "a41e1b6d-40ee-456e-94d7-9169e0f5b188", "label": "b", "points": [[308.5, 5.2], [308.5, 286.4], [648.4, 286.4], [648.4, 5.2]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "STM", "start": 8, "end": 11, "id": 4}, {"text": "images", "start": 12, "end": 18, "id": 5}, {"text": "300", "start": 19, "end": 22, "id": 6}, {"text": "300", "start": 23, "end": 26, "id": 7}, {"text": "nm2", "start": 27, "end": 30, "id": 8}, {"text": "showing", "start": 31, "end": 38, "id": 9}, {"text": "rapid", "start": 39, "end": 44, "id": 10}, {"text": "decay", "start": 45, "end": 50, "id": 11}, {"text": "of", "start": 51, "end": 53, "id": 12}, {"text": "adatom", "start": 54, "end": 60, "id": 13}, {"text": "islands", "start": 61, "end": 68, "id": 14}, {"text": "while", "start": 69, "end": 74, "id": 15}, {"text": "S", "start": 75, "end": 76, "id": 16}, {"text": "increases", "start": 77, "end": 86, "id": 17}, {"text": "to", "start": 87, "end": 89, "id": 18}, {"text": "35", "start": 90, "end": 92, "id": 19}, {"text": "mML", "start": 93, "end": 96, "id": 20}, {"text": ":", "start": 96, "end": 97, "id": 21}, {"text": "a", "start": 98, "end": 99, "id": 22}, {"text": "island", "start": 100, "end": 106, "id": 23}, {"text": "distribution", "start": 107, "end": 119, "id": 24}, {"text": "before", "start": 120, "end": 126, "id": 25}, {"text": "exposure", "start": 127, "end": 135, "id": 26}, {"text": "to", "start": 136, "end": 138, "id": 27}, {"text": "S", "start": 139, "end": 140, "id": 28}, {"text": ",", "start": 140, "end": 141, "id": 29}, {"text": "b", "start": 142, "end": 143, "id": 30}, {"text": "imaging", "start": 144, "end": 151, "id": 31}, {"text": "during", "start": 152, "end": 158, "id": 32}, {"text": "S", "start": 159, "end": 160, "id": 33}, {"text": "exposure", "start": 161, "end": 169, "id": 34}, {"text": ",", "start": 169, "end": 170, "id": 35}, {"text": "which", "start": 171, "end": 176, "id": 36}, {"text": "starts", "start": 177, "end": 183, "id": 37}, {"text": "at", "start": 184, "end": 186, "id": 38}, {"text": "the", "start": 187, "end": 190, "id": 39}, {"text": "bottom", "start": 191, "end": 197, "id": 40}, {"text": "as", "start": 198, "end": 200, "id": 41}, {"text": "indicated", "start": 201, "end": 210, "id": 42}, {"text": "by", "start": 211, "end": 213, "id": 43}, {"text": "a", "start": 214, "end": 215, "id": 44}, {"text": "lower", "start": 216, "end": 221, "id": 45}, {"text": "arrow", "start": 222, "end": 227, "id": 46}, {"text": "and", "start": 228, "end": 231, "id": 47}, {"text": "which", "start": 232, "end": 237, "id": 48}, {"text": "is", "start": 238, "end": 240, "id": 49}, {"text": "completed", "start": 241, "end": 250, "id": 50}, {"text": "at", "start": 251, "end": 253, "id": 51}, {"text": "the", "start": 254, "end": 257, "id": 52}, {"text": "top", "start": 258, "end": 261, "id": 53}, {"text": "arrow", "start": 262, "end": 267, "id": 54}, {"text": ".", "start": 267, "end": 268, "id": 55}, {"text": "We", "start": 269, "end": 271, "id": 56}, {"text": "also", "start": 272, "end": 276, "id": 57}, {"text": "indicate", "start": 277, "end": 285, "id": 58}, {"text": "the", "start": 286, "end": 289, "id": 59}, {"text": "change", "start": 290, "end": 296, "id": 60}, {"text": "in", "start": 297, "end": 299, "id": 61}, {"text": "size", "start": 300, "end": 304, "id": 62}, {"text": "in", "start": 305, "end": 307, "id": 63}, {"text": "nm2", "start": 308, "end": 311, "id": 64}, {"text": "of", "start": 312, "end": 314, "id": 65}, {"text": "two", "start": 315, "end": 318, "id": 66}, {"text": "selected", "start": 319, "end": 327, "id": 67}, {"text": "islands", "start": 328, "end": 335, "id": 68}, {"text": "near", "start": 336, "end": 340, "id": 69}, {"text": "the", "start": 341, "end": 344, "id": 70}, {"text": "bottom", "start": 345, "end": 351, "id": 71}, {"text": "of", "start": 352, "end": 354, "id": 72}, {"text": "the", "start": 355, "end": 358, "id": 73}, {"text": "images", "start": 359, "end": 365, "id": 74}, {"text": ".", "start": 365, "end": 366, "id": 75}]}
{"pdf_hash": "5cb0894f6fa8b10091932f4bf7a52aa6d5bb6d30", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Sagittal reconstructed (A) and volume rendering (B) dual source CT images of a 15-day girl with a large PDA and PAH. (PDA: patent ductus arteriosus; PAH: pulmonary arterial hypertension).", "width": 1262, "height": 1048, "subcaptions": {"a": [3, 4, 5, 6, 7], "b": [9, 10, 11, 12, 13]}, "subfigures": [{"id": "01df4f95-8a2f-47de-b800-5367374abe8d", "label": "a", "points": [[2, 0], [2, 522.3], [394.8, 522.3], [394.8, 0]], "color": "yellow"}, {"id": "f9f7d1e0-bb86-401e-b105-6b9a168848a9", "label": "b", "points": [[400.7, 2], [400.7, 520.4], [785.5, 520.4], [785.5, 2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Sagittal", "start": 10, "end": 18, "id": 3}, {"text": "reconstructed", "start": 19, "end": 32, "id": 4}, {"text": "(", "start": 33, "end": 34, "id": 5}, {"text": "A", "start": 34, "end": 35, "id": 6}, {"text": ")", "start": 35, "end": 36, "id": 7}, {"text": "and", "start": 37, "end": 40, "id": 8}, {"text": "volume", "start": 41, "end": 47, "id": 9}, {"text": "rendering", "start": 48, "end": 57, "id": 10}, {"text": "(", "start": 58, "end": 59, "id": 11}, {"text": "B", "start": 59, "end": 60, "id": 12}, {"text": ")", "start": 60, "end": 61, "id": 13}, {"text": "dual", "start": 62, "end": 66, "id": 14}, {"text": "source", "start": 67, "end": 73, "id": 15}, {"text": "CT", "start": 74, "end": 76, "id": 16}, {"text": "images", "start": 77, "end": 83, "id": 17}, {"text": "of", "start": 84, "end": 86, "id": 18}, {"text": "a", "start": 87, "end": 88, "id": 19}, {"text": "15-day", "start": 89, "end": 95, "id": 20}, {"text": "girl", "start": 96, "end": 100, "id": 21}, {"text": "with", "start": 101, "end": 105, "id": 22}, {"text": "a", "start": 106, "end": 107, "id": 23}, {"text": "large", "start": 108, "end": 113, "id": 24}, {"text": "PDA", "start": 114, "end": 117, "id": 25}, {"text": "and", "start": 118, "end": 121, "id": 26}, {"text": "PAH", "start": 122, "end": 125, "id": 27}, {"text": ".", "start": 125, "end": 126, "id": 28}, {"text": "(", "start": 127, "end": 128, "id": 29}, {"text": "PDA", "start": 128, "end": 131, "id": 30}, {"text": ":", "start": 131, "end": 132, "id": 31}, {"text": "patent", "start": 133, "end": 139, "id": 32}, {"text": "ductus", "start": 140, "end": 146, "id": 33}, {"text": "arteriosus", "start": 147, "end": 157, "id": 34}, {"text": ";", "start": 157, "end": 158, "id": 35}, {"text": "PAH", "start": 159, "end": 162, "id": 36}, {"text": ":", "start": 162, "end": 163, "id": 37}, {"text": "pulmonary", "start": 164, "end": 173, "id": 38}, {"text": "arterial", "start": 174, "end": 182, "id": 39}, {"text": "hypertension", "start": 183, "end": 195, "id": 40}, {"text": ")", "start": 195, "end": 196, "id": 41}, {"text": ".", "start": 196, "end": 197, "id": 42}]}
{"pdf_hash": "dc0dfa01153a7f826906e7d4e98e806f80968a3f", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Endoscopic view. (A) Intraoperative endoscopic view of retained ballistic fragment located within the left fossa of Rosenmuller. The bilateral Eustachian tubes are visualized. Traumatic changes are noted in the nasopharynx and the patient\u2019s left Eustachian tube which is displaced laterally by the suction tip. The soft palate is labeled for reference. (B) Intraoperative endoscopic view of dural defect after resection of necrotic tissue and extraction of the ballistic fragment. Cerebrospinal fluid was noted to egress from the dural defect. 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{"pdf_hash": "3b0c9564bb958b27755179a009301be25c31a6d3", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Pre- and postoperative MRI of second PELD. A and B, Preoperative MRI revealed recurrent disc herniation was identified on L4-L5. The right foramen and nerve root was compressed by disc hernia. C, Resected disc fragment in the second operation. D and E, Postoperative MRI showed decompressed spinal canal and foraminal area.", "width": 1334, "height": 956, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "b": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "c": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "d": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61], "e": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "ce966688-efcd-4528-b39a-cc6d74536358", "label": "a", "points": [[44.6, 26], [44.6, 439.1], [445, 439.1], [445, 26]], "color": "yellow"}, {"id": "4046d1f3-5cb9-46c3-bb17-7ca9690ade8c", "label": "b", "points": [[466.1, 21.8], [466.1, 441.2], [875, 441.2], [875, 21.8]], "color": "cyan"}, {"id": "09c66b5a-5ca2-43d4-bc75-df200d1ed6dd", "label": "c", "points": [[893.9, 26], [893.9, 434.8], [1300.7, 434.8], [1300.7, 26]], "color": "magenta"}, {"id": "0326555c-8a86-4300-aeac-36e8e3acd832", "label": "d", "points": [[32, 485.4], [32, 902.7], [449.2, 902.7], [449.2, 485.4]], "color": "springgreen"}, {"id": "f000c1f1-31a4-4811-b376-a259cf9ad76f", "label": "e", "points": [[457.7, 481.2], [457.7, 890.1], [1298.6, 890.1], [1298.6, 481.2]], "color": "tomato"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Pre-", "start": 10, "end": 14, "id": 3}, {"text": "and", "start": 15, "end": 18, "id": 4}, {"text": "postoperative", "start": 19, "end": 32, "id": 5}, {"text": "MRI", "start": 33, "end": 36, "id": 6}, {"text": "of", "start": 37, "end": 39, "id": 7}, {"text": "second", "start": 40, "end": 46, "id": 8}, {"text": "PELD", "start": 47, "end": 51, "id": 9}, {"text": ".", "start": 51, "end": 52, "id": 10}, {"text": "A", "start": 53, "end": 54, "id": 11}, {"text": "and", "start": 55, "end": 58, "id": 12}, {"text": "B", "start": 59, "end": 60, "id": 13}, {"text": ",", "start": 60, "end": 61, "id": 14}, {"text": "Preoperative", "start": 62, "end": 74, "id": 15}, {"text": "MRI", "start": 75, "end": 78, "id": 16}, {"text": "revealed", "start": 79, "end": 87, "id": 17}, {"text": "recurrent", "start": 88, "end": 97, "id": 18}, {"text": "disc", "start": 98, "end": 102, "id": 19}, {"text": "herniation", "start": 103, "end": 113, "id": 20}, {"text": "was", "start": 114, "end": 117, "id": 21}, {"text": "identified", "start": 118, "end": 128, "id": 22}, {"text": "on", "start": 129, "end": 131, "id": 23}, {"text": "L4-L5", "start": 132, "end": 137, "id": 24}, {"text": ".", "start": 137, "end": 138, "id": 25}, {"text": "The", "start": 139, "end": 142, "id": 26}, {"text": "right", "start": 143, "end": 148, "id": 27}, {"text": "foramen", "start": 149, "end": 156, "id": 28}, {"text": "and", "start": 157, "end": 160, "id": 29}, {"text": "nerve", "start": 161, "end": 166, "id": 30}, {"text": "root", "start": 167, "end": 171, "id": 31}, {"text": "was", "start": 172, "end": 175, "id": 32}, {"text": "compressed", "start": 176, "end": 186, "id": 33}, {"text": "by", "start": 187, "end": 189, "id": 34}, {"text": "disc", "start": 190, "end": 194, "id": 35}, {"text": "hernia", "start": 195, "end": 201, "id": 36}, {"text": ".", "start": 201, "end": 202, "id": 37}, {"text": "C", "start": 203, "end": 204, "id": 38}, {"text": ",", "start": 204, "end": 205, "id": 39}, {"text": "Resected", "start": 206, "end": 214, "id": 40}, {"text": "disc", "start": 215, "end": 219, "id": 41}, {"text": "fragment", "start": 220, "end": 228, "id": 42}, {"text": "in", "start": 229, "end": 231, "id": 43}, {"text": "the", "start": 232, "end": 235, "id": 44}, {"text": "second", "start": 236, "end": 242, "id": 45}, {"text": "operation", "start": 243, "end": 252, "id": 46}, {"text": ".", "start": 252, "end": 253, "id": 47}, {"text": "D", "start": 254, "end": 255, "id": 48}, {"text": "and", "start": 256, "end": 259, "id": 49}, {"text": "E", "start": 260, "end": 261, "id": 50}, {"text": ",", "start": 261, "end": 262, "id": 51}, {"text": "Postoperative", "start": 263, "end": 276, "id": 52}, {"text": "MRI", "start": 277, "end": 280, "id": 53}, {"text": "showed", "start": 281, "end": 287, "id": 54}, {"text": "decompressed", "start": 288, "end": 300, "id": 55}, {"text": "spinal", "start": 301, "end": 307, "id": 56}, {"text": "canal", "start": 308, "end": 313, "id": 57}, {"text": "and", "start": 314, "end": 317, "id": 58}, {"text": "foraminal", "start": 318, "end": 327, "id": 59}, {"text": "area", "start": 328, "end": 332, "id": 60}, {"text": ".", "start": 332, "end": 333, "id": 61}]}
{"pdf_hash": "07a9e044e33c30210ba7cf83ba6532b78fd2de80", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Fig 6. Endoscopic management of calcaneofibular impingement and posterior ankle impingement syndrome of right foot and ankle. The patient is in the prone position. Preoperative and postoperative computed tomograms (CTs) of the right foot are shown for the illustrated case. (A) The preoperative sagittal CT view shows the posterior calcaneal bone spike (CS). (B) The preoperative sagittal CT view shows calcaneofibular impingement (arrowhead). (C) The postoperative sagittal CT view shows that the posterior calcaneal bone spike has been resected. 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{"pdf_hash": "56a006e8711ece9cd54786d3a272bb997c67fe94", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4. SPM{t} maps of voxelwise correlations between grey matter volume and the variability of the early saccade population (\u03c3E) in patients (A) and controls (B). Anatomical localization as projected on axial sections of a normalMRI, spatially normalised into theMNI template (pb0.05, FWE corrected formultiple comparisons) at the given z coordinates in MNI space. 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Dual study using [68Ga]Ga-GallGas (left) and [99mTc]-Technegas (right) in healthy piglets demonstrating similarity in ventilation distribution (A), in piglets with lower lobar obstruction (B), and in the piglets with diffuse airway obstruction induced by infusion of methacholine (C).", "width": 1288, "height": 214, "subcaptions": {"a": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49], "b": [51, 52, 53, 54, 55, 56, 57, 58, 59], "c": [62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77]}, "subfigures": [{"id": "04fe0389-6224-4993-8628-98949bf97f9c", "label": "a", "points": [[26.8, 12.9], [26.8, 173.6], [399.2, 173.6], [399.2, 12.9]], "color": "yellow"}, {"id": "83a1665d-4a13-4d42-ac68-a6b90f527720", "label": "b", "points": [[458.2, 12.9], [458.2, 173.6], [798, 173.6], [798, 12.9]], "color": "cyan"}, {"id": "6dcdebc2-5522-45a7-bf34-d89283906d40", "label": "c", "points": [[852.9, 4.7], [852.9, 181.8], [1264, 181.8], [1264, 4.7]], "color": "magenta"}], "tokens": [{"text": "Fig", 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Contrast-enhanced computed tomography (frontal plane) showing (A) presence of only left portal vein (LPV) and left hepatic artery (LHA) and absence of right portal vein and right hepatic artery and (B) dominant pattern of left hepatic vein (LHV) and absence of right and middle hepatic veins (PV \u2013 main portal vein; CHA \u2013 common hepatic artery; GDA \u2013 gastro-duodenal artery).", "width": 1072, "height": 470, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "b": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "9221fe82-f856-481f-b87e-2a29166022e3", "label": "a", "points": [[2.5, 3.4], [2.5, 433.6], [525.9, 433.6], [525.9, 3.4]], "color": "yellow"}, {"id": "f673882a-6207-4360-ab95-c19e1bcdca99", "label": "b", "points": [[536, 1.7], [536, 435.3], [1064.4, 435.3], [1064.4, 1.7]], "color": "cyan"}], "tokens": [{"text": "Figure", 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{"pdf_hash": "ac93792378c668cecf5b8a152a49a3fef8990f42", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Mass lesion with hypointensity in T1-weighted images (arrow) (A), with slightly lower signal than CSF in T2-weighted images (arrow) (B), and slightly heterogeneous gadolinium-enhanced T1-weighted images (C) upon sagittal thoracic spine MRI. CSF : cerebrospinal fluid. C B A", "width": 1300, "height": 506, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [32, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "0ea09158-69ed-415a-bdb4-8c5d90f491a5", "label": "a", "points": [[0, 6.2], [0, 486.7], [423.1, 486.7], [423.1, 6.2]], "color": "yellow"}, {"id": "d571889a-9f45-4305-bb09-5743f9cf7e86", "label": "b", "points": [[435.4, 486.7], [435.4, 4.1], [862.6, 4.1], [862.6, 486.7]], "color": "cyan"}, {"id": "37add847-206c-4b90-9ae0-339c96017497", "label": "c", "points": [[868.7, 4.1], [868.7, 476.5], [1295.9, 476.5], [1295.9, 4.1]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Mass", "start": 8, "end": 12, "id": 4}, {"text": "lesion", "start": 13, "end": 19, "id": 5}, {"text": "with", "start": 20, "end": 24, "id": 6}, {"text": "hypointensity", "start": 25, "end": 38, "id": 7}, {"text": "in", "start": 39, "end": 41, "id": 8}, {"text": "T1-weighted", "start": 42, "end": 53, "id": 9}, {"text": "images", "start": 54, "end": 60, "id": 10}, {"text": "(", "start": 61, "end": 62, "id": 11}, {"text": "arrow", "start": 62, "end": 67, "id": 12}, {"text": ")", "start": 67, "end": 68, "id": 13}, {"text": "(", "start": 69, "end": 70, "id": 14}, {"text": "A", "start": 70, "end": 71, "id": 15}, {"text": ")", "start": 71, "end": 72, "id": 16}, {"text": ",", "start": 72, "end": 73, "id": 17}, {"text": "with", "start": 74, "end": 78, "id": 18}, {"text": "slightly", "start": 79, "end": 87, "id": 19}, {"text": "lower", "start": 88, "end": 93, "id": 20}, {"text": "signal", "start": 94, "end": 100, "id": 21}, {"text": "than", "start": 101, "end": 105, "id": 22}, {"text": "CSF", "start": 106, "end": 109, "id": 23}, {"text": "in", "start": 110, "end": 112, "id": 24}, {"text": "T2-weighted", "start": 113, "end": 124, "id": 25}, {"text": "images", "start": 125, "end": 131, "id": 26}, {"text": "(", "start": 132, "end": 133, "id": 27}, {"text": "arrow", "start": 133, "end": 138, "id": 28}, {"text": ")", "start": 138, "end": 139, "id": 29}, {"text": "(", "start": 140, "end": 141, "id": 30}, {"text": "B", "start": 141, "end": 142, "id": 31}, {"text": ")", "start": 142, "end": 143, "id": 32}, {"text": ",", "start": 143, "end": 144, "id": 33}, {"text": "and", "start": 145, "end": 148, "id": 34}, {"text": "slightly", "start": 149, "end": 157, "id": 35}, {"text": "heterogeneous", "start": 158, "end": 171, "id": 36}, {"text": "gadolinium", "start": 172, "end": 182, "id": 37}, {"text": "-", "start": 182, "end": 183, "id": 38}, {"text": "enhanced", "start": 183, "end": 191, "id": 39}, {"text": "T1-weighted", "start": 192, "end": 203, "id": 40}, {"text": "images", "start": 204, "end": 210, "id": 41}, {"text": "(", "start": 211, "end": 212, "id": 42}, {"text": "C", "start": 212, "end": 213, "id": 43}, {"text": ")", "start": 213, "end": 214, "id": 44}, {"text": "upon", "start": 215, "end": 219, "id": 45}, {"text": "sagittal", "start": 220, "end": 228, "id": 46}, {"text": "thoracic", "start": 229, "end": 237, "id": 47}, {"text": "spine", "start": 238, "end": 243, "id": 48}, {"text": "MRI", "start": 244, "end": 247, "id": 49}, {"text": ".", "start": 247, "end": 248, "id": 50}, {"text": "CSF", "start": 249, "end": 252, "id": 51}, {"text": ":", "start": 253, "end": 254, "id": 52}, {"text": "cerebrospinal", "start": 255, "end": 268, "id": 53}, {"text": "fluid", "start": 269, "end": 274, "id": 54}, {"text": ".", "start": 274, "end": 275, "id": 55}, {"text": "C", "start": 276, "end": 277, "id": 56}, {"text": "B", "start": 278, "end": 279, "id": 57}, {"text": "A", "start": 280, "end": 281, "id": 58}]}
{"pdf_hash": "30d0bffcaddc1ea3c5b44fe4d60af062991dcd14", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Figure 4 \u2013 Thoracic radiography with distended intestinal loops on the upper abdomen (A); Abdominal echography with distended intestinal loops and slight amount of inter-loops liquid (B).", "width": 1338, "height": 614, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34]}, "subfigures": [{"id": "3800e239-88b1-4ecb-986c-676ccf4c6ffc", "label": "a", "points": [[11.6, 0], [11.6, 583.4], [512.6, 583.4], [512.6, 0]], "color": "yellow"}, {"id": "5d8d11d7-2f36-48a8-8d50-b35e7613c75c", "label": "b", "points": [[521.1, 2.1], [521.1, 581.3], [1328.5, 581.3], [1328.5, 2.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": "\u2013", "start": 9, "end": 10, "id": 2}, {"text": "Thoracic", "start": 11, "end": 19, "id": 3}, {"text": "radiography", "start": 20, "end": 31, "id": 4}, {"text": "with", "start": 32, "end": 36, "id": 5}, {"text": "distended", "start": 37, "end": 46, "id": 6}, {"text": "intestinal", "start": 47, "end": 57, "id": 7}, {"text": "loops", "start": 58, "end": 63, "id": 8}, {"text": "on", "start": 64, "end": 66, "id": 9}, {"text": "the", "start": 67, "end": 70, "id": 10}, {"text": "upper", "start": 71, "end": 76, "id": 11}, {"text": "abdomen", "start": 77, "end": 84, "id": 12}, {"text": "(", "start": 85, "end": 86, "id": 13}, {"text": "A", "start": 86, "end": 87, "id": 14}, {"text": ")", "start": 87, "end": 88, "id": 15}, {"text": ";", "start": 88, "end": 89, "id": 16}, {"text": "Abdominal", "start": 90, "end": 99, "id": 17}, {"text": "echography", "start": 100, "end": 110, "id": 18}, {"text": "with", "start": 111, "end": 115, "id": 19}, {"text": "distended", "start": 116, "end": 125, "id": 20}, {"text": "intestinal", "start": 126, "end": 136, "id": 21}, {"text": "loops", "start": 137, "end": 142, "id": 22}, {"text": "and", "start": 143, "end": 146, "id": 23}, {"text": "slight", "start": 147, "end": 153, "id": 24}, {"text": "amount", "start": 154, "end": 160, "id": 25}, {"text": "of", "start": 161, "end": 163, "id": 26}, {"text": "inter", "start": 164, "end": 169, "id": 27}, {"text": "-", "start": 169, "end": 170, "id": 28}, {"text": "loops", "start": 170, "end": 175, "id": 29}, {"text": "liquid", "start": 176, "end": 182, "id": 30}, {"text": "(", "start": 183, "end": 184, "id": 31}, {"text": "B", "start": 184, "end": 185, "id": 32}, {"text": ")", "start": 185, "end": 186, "id": 33}, {"text": ".", "start": 186, "end": 187, "id": 34}]}
{"pdf_hash": "d9cd6ed9082131539face060990af1665d9579de", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. a) A retroflex view of the stomach shows edematous and hypertrophic mucosa with reddened giant folds covered with thick mucus. b) Mucosa of the gastric antrum shows reddened hypertrophic mucosa with granular changes. c) Narrow-band imaging (NBI) of the mucosa of the cardia shows hypertrophic mucosa. d) Magnification with NBI of the mucosa in the yellow square of (c) shows enlarged marginal crypt epithelium of variable size and shape. e) NBI of mucosa of the antrum shows granular changes with multiple brownish areas. f) Magnification with NBI of the mucosa in the green square of (e) shows enlarged marginal crypt epithelia of variable size and shape, findings similar to those in the gastric body.", "width": 960, "height": 1284, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24], "b": [25, 26, 27, 28, 29, 30, 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{"pdf_hash": "28bfeb6ed13e707f1b053e83d5ca38c68427fb36", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig 1. Representative images of a focal lesion (FL) in left pelvis showing changes after 8 weeks. A FL (red arrow) on (A) pre-contrast fat-only, (B) pre-contrast water-only, (C) post-contrast water only mDixon and (D) b1000 diffusion weighted imaging at baseline (A1\u2013D1) and 8 weeks (A2\u2013D2) in a patient who achieved very good partial response (VGPR) after induction chemotherapy. Estimated tumour volume (eTV), signal fat fraction (sFF), enhancement ratio (ER) and apparent diffusion coefficient (ADC) were 4 5 cm3, 0 11 a.u., 167 8% and 1 13 9 10 3 mm2/s at baseline, respectively. At 8 weeks after starting chemotherapy, eTV, sFF, ER and ADC were 3 96 cm3, 0 23 a.u., 197 5% and 1 97 9 10 3 mm2/s, representing a 12% reduction in eTV, 109% increase in sFF, 17 6% increase in ER and 74 3% increase in ADC. 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{"pdf_hash": "fd75d1f53e140f2ba3e3091dd900c3b5509099a8", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. CT finding at recurrence and terminal stage. (A) Chest CT indicates the lung metastases at pretreatment with bevacizumab and paclitaxel. (B) Brain CT at terminal stage indicated meningeal metastasis.", "width": 1292, "height": 730, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "825c5f2d-dbc4-4d73-987c-e4d687842966", "label": "a", "points": [[11.3, 5.8], [11.3, 693.6], [662.4, 693.6], [662.4, 5.8]], "color": "yellow"}, {"id": "7c53a9c1-63e6-4f57-82eb-d3415d9f3903", "label": "b", "points": [[670.5, 3.7], [670.5, 689.5], [1282.8, 689.5], [1282.8, 3.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "finding", "start": 13, "end": 20, "id": 4}, {"text": "at", "start": 21, "end": 23, "id": 5}, {"text": "recurrence", "start": 24, "end": 34, "id": 6}, {"text": "and", "start": 35, "end": 38, "id": 7}, {"text": "terminal", "start": 39, "end": 47, "id": 8}, {"text": "stage", "start": 48, "end": 53, "id": 9}, {"text": ".", "start": 53, "end": 54, "id": 10}, {"text": "(", "start": 55, "end": 56, "id": 11}, {"text": "A", "start": 56, "end": 57, "id": 12}, {"text": ")", "start": 57, "end": 58, "id": 13}, {"text": "Chest", "start": 59, "end": 64, "id": 14}, {"text": "CT", "start": 65, "end": 67, "id": 15}, {"text": "indicates", "start": 68, "end": 77, "id": 16}, {"text": "the", "start": 78, "end": 81, "id": 17}, {"text": "lung", "start": 82, "end": 86, "id": 18}, {"text": "metastases", "start": 87, "end": 97, "id": 19}, {"text": "at", "start": 98, "end": 100, "id": 20}, {"text": "pretreatment", "start": 101, "end": 113, "id": 21}, {"text": "with", "start": 114, "end": 118, "id": 22}, {"text": "bevacizumab", "start": 119, "end": 130, "id": 23}, {"text": "and", "start": 131, "end": 134, "id": 24}, {"text": "paclitaxel", "start": 135, "end": 145, "id": 25}, {"text": ".", "start": 145, "end": 146, "id": 26}, {"text": "(", "start": 147, "end": 148, "id": 27}, {"text": "B", "start": 148, "end": 149, "id": 28}, {"text": ")", "start": 149, "end": 150, "id": 29}, {"text": "Brain", "start": 151, "end": 156, "id": 30}, {"text": "CT", "start": 157, "end": 159, "id": 31}, {"text": "at", "start": 160, "end": 162, "id": 32}, {"text": "terminal", "start": 163, "end": 171, "id": 33}, {"text": "stage", "start": 172, "end": 177, "id": 34}, {"text": "indicated", "start": 178, "end": 187, "id": 35}, {"text": "meningeal", "start": 188, "end": 197, "id": 36}, {"text": "metastasis", "start": 198, "end": 208, "id": 37}, {"text": ".", "start": 208, "end": 209, "id": 38}]}
{"pdf_hash": "24aeac332dc52f166e4e3ae6f9fbb8900650e4de", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Pre-operative non-contrast CT and fluoroscopic images of Patient 2. (a). Right ureter (straight arrow) displaced anteriorly from the psoas muscle (*) at the level of L4\u2013L5. Compare this to the normally positioned left ureter (curved arrow) in close proximity to the psoas muscle (*). (b) Right ureter (straight arrow) in the inguinal hernia. (c) Anterograde nephrostogram with the patient in prone position at the time of nephrostomy tube insertion. 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{"pdf_hash": "f63d545f6b80fc02ec7b414e0717c496b40f853f", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2: 15-year-old thalassemic diabetic female patient. (a) Axial T2WI revealed decreased signal intensity of the liver. (b) Axial T2 * GRE images revealed more drop in the signal intensity of the liver.", "width": 1042, "height": 464, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "b82e38ad-d9de-4881-ab29-11600c912517", "label": "a", "points": [[37, 1.6], [37, 396.7], [504.6, 396.7], [504.6, 1.6]], "color": "yellow"}, {"id": "35aa820a-2368-4154-b441-53ca1e9736b1", "label": "b", "points": [[532.5, 0], [532.5, 390.2], [1003.4, 390.2], [1003.4, 0]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "15-year", "start": 10, "end": 17, "id": 3}, {"text": "-", "start": 17, "end": 18, "id": 4}, {"text": "old", "start": 18, "end": 21, "id": 5}, {"text": "thalassemic", "start": 22, "end": 33, "id": 6}, {"text": "diabetic", "start": 34, "end": 42, "id": 7}, {"text": "female", "start": 43, "end": 49, "id": 8}, {"text": "patient", "start": 50, "end": 57, "id": 9}, {"text": ".", "start": 57, "end": 58, "id": 10}, {"text": "(", "start": 59, "end": 60, "id": 11}, {"text": "a", "start": 60, "end": 61, "id": 12}, {"text": ")", "start": 61, "end": 62, "id": 13}, {"text": "Axial", "start": 63, "end": 68, "id": 14}, {"text": "T2WI", "start": 69, "end": 73, "id": 15}, {"text": "revealed", "start": 74, "end": 82, "id": 16}, {"text": "decreased", "start": 83, "end": 92, "id": 17}, {"text": "signal", "start": 93, "end": 99, "id": 18}, {"text": "intensity", "start": 100, "end": 109, "id": 19}, {"text": "of", "start": 110, "end": 112, "id": 20}, {"text": "the", "start": 113, "end": 116, "id": 21}, {"text": "liver", "start": 117, "end": 122, "id": 22}, {"text": ".", "start": 122, "end": 123, "id": 23}, {"text": "(", "start": 124, "end": 125, "id": 24}, {"text": "b", "start": 125, "end": 126, "id": 25}, {"text": ")", "start": 126, "end": 127, "id": 26}, {"text": "Axial", "start": 128, "end": 133, "id": 27}, {"text": "T2", "start": 134, "end": 136, "id": 28}, {"text": "*", "start": 137, "end": 138, "id": 29}, {"text": "GRE", "start": 139, "end": 142, "id": 30}, {"text": "images", "start": 143, "end": 149, "id": 31}, {"text": "revealed", "start": 150, "end": 158, "id": 32}, {"text": "more", "start": 159, "end": 163, "id": 33}, {"text": "drop", "start": 164, "end": 168, "id": 34}, {"text": "in", "start": 169, "end": 171, "id": 35}, {"text": "the", "start": 172, "end": 175, "id": 36}, {"text": "signal", "start": 176, "end": 182, "id": 37}, {"text": "intensity", "start": 183, "end": 192, "id": 38}, {"text": "of", "start": 193, "end": 195, "id": 39}, {"text": "the", "start": 196, "end": 199, "id": 40}, {"text": "liver", "start": 200, "end": 205, "id": 41}, {"text": ".", "start": 205, "end": 206, "id": 42}]}
{"pdf_hash": "5f848438ea5c261533f1614f5bea852a688a565c", "fig_key": "Figure6", "fig_uri": "9-Figure6-1.png", "text": "Figure 6. Transmission electron micrographs of Trypanosoma noyesi sp. n. A. longitudinal section showing the kinetoplast (white arrowhead), flagellum, acidocalcisomes (black arrowhead), glycosomes (white asterix), and reservosomes (black asterix). B. transverse section revealing the flagellum, axoneme, mitochondrion (arrowhead), and extension of the flagellar sheath (asterix). 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{"pdf_hash": "7e3109afd14a1699a51ac0463efaaba7231a68ec", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1 Chest radiograph of a 65-year-old man (RM) with histiocytic medullary reticulosis receiving cytotoxic drugs and prednisone: (a) shows a bilateral, predominantly nodular infiltrate; (b) demonstrates the position of the biopsy forceps in the left upper lung zone during fibreoptic bronchoscopy. Aspergillus fumigatus was isolated on both transbronchial brush and forceps biopsies. Aspergillus precipitins rose from a titre of 1:8 to 1:32.", "width": 754, "height": 1324, "subcaptions": {"a": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "ff5070da-651a-49c3-ad02-93816a83064b", "label": "a", "points": [[4.2, 4.4], [4.2, 629.7], [748.6, 629.7], [748.6, 4.4]], "color": "yellow"}, {"id": "0ff6ca5a-6fba-4dd7-8a4b-53ac163006fd", "label": "b", "points": [[107.8, 676.2], [107.8, 1292], [653.4, 1292], [653.4, 676.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Chest", "start": 7, "end": 12, "id": 3}, {"text": "radiograph", "start": 13, "end": 23, "id": 4}, {"text": "of", "start": 24, "end": 26, "id": 5}, {"text": "a", "start": 27, "end": 28, "id": 6}, {"text": "65-year", "start": 29, "end": 36, "id": 7}, {"text": "-", "start": 36, "end": 37, "id": 8}, {"text": "old", "start": 37, "end": 40, "id": 9}, {"text": "man", "start": 41, "end": 44, "id": 10}, {"text": "(", "start": 45, "end": 46, "id": 11}, {"text": "RM", "start": 46, "end": 48, "id": 12}, {"text": ")", "start": 48, "end": 49, "id": 13}, {"text": "with", "start": 50, "end": 54, "id": 14}, {"text": "histiocytic", "start": 55, "end": 66, "id": 15}, {"text": "medullary", "start": 67, "end": 76, "id": 16}, {"text": "reticulosis", "start": 77, "end": 88, "id": 17}, {"text": "receiving", "start": 89, "end": 98, "id": 18}, {"text": "cytotoxic", "start": 99, "end": 108, "id": 19}, {"text": "drugs", "start": 109, "end": 114, "id": 20}, {"text": "and", "start": 115, "end": 118, "id": 21}, {"text": "prednisone", "start": 119, "end": 129, "id": 22}, {"text": ":", "start": 129, "end": 130, "id": 23}, {"text": "(", "start": 131, "end": 132, "id": 24}, {"text": "a", "start": 132, "end": 133, "id": 25}, {"text": ")", "start": 133, "end": 134, "id": 26}, {"text": "shows", "start": 135, "end": 140, "id": 27}, {"text": "a", "start": 141, "end": 142, "id": 28}, {"text": "bilateral", "start": 143, "end": 152, "id": 29}, {"text": ",", "start": 152, "end": 153, "id": 30}, {"text": "predominantly", "start": 154, "end": 167, "id": 31}, {"text": "nodular", "start": 168, "end": 175, "id": 32}, {"text": "infiltrate", "start": 176, "end": 186, "id": 33}, {"text": ";", "start": 186, "end": 187, "id": 34}, {"text": "(", "start": 188, "end": 189, "id": 35}, {"text": "b", "start": 189, "end": 190, "id": 36}, {"text": ")", "start": 190, "end": 191, "id": 37}, {"text": "demonstrates", "start": 192, "end": 204, "id": 38}, {"text": "the", "start": 205, "end": 208, "id": 39}, {"text": "position", "start": 209, "end": 217, "id": 40}, {"text": "of", "start": 218, "end": 220, "id": 41}, {"text": "the", "start": 221, "end": 224, "id": 42}, {"text": "biopsy", "start": 225, "end": 231, "id": 43}, {"text": "forceps", "start": 232, "end": 239, "id": 44}, {"text": "in", "start": 240, "end": 242, "id": 45}, {"text": "the", "start": 243, "end": 246, "id": 46}, {"text": "left", "start": 247, "end": 251, "id": 47}, {"text": "upper", "start": 252, "end": 257, "id": 48}, {"text": "lung", "start": 258, "end": 262, "id": 49}, {"text": "zone", "start": 263, "end": 267, "id": 50}, {"text": "during", "start": 268, "end": 274, "id": 51}, {"text": "fibreoptic", "start": 275, "end": 285, "id": 52}, {"text": "bronchoscopy", "start": 286, "end": 298, "id": 53}, {"text": ".", "start": 298, "end": 299, "id": 54}, {"text": "Aspergillus", "start": 300, "end": 311, "id": 55}, {"text": "fumigatus", "start": 312, "end": 321, "id": 56}, {"text": "was", "start": 322, "end": 325, "id": 57}, {"text": "isolated", "start": 326, "end": 334, "id": 58}, {"text": "on", "start": 335, "end": 337, "id": 59}, {"text": "both", "start": 338, "end": 342, "id": 60}, {"text": "transbronchial", "start": 343, "end": 357, "id": 61}, {"text": "brush", "start": 358, "end": 363, "id": 62}, {"text": "and", "start": 364, "end": 367, "id": 63}, {"text": "forceps", "start": 368, "end": 375, "id": 64}, {"text": "biopsies", "start": 376, "end": 384, "id": 65}, {"text": ".", "start": 384, "end": 385, "id": 66}, {"text": "Aspergillus", "start": 386, "end": 397, "id": 67}, {"text": "precipitins", "start": 398, "end": 409, "id": 68}, {"text": "rose", "start": 410, "end": 414, "id": 69}, {"text": "from", "start": 415, "end": 419, "id": 70}, {"text": "a", "start": 420, "end": 421, "id": 71}, {"text": "titre", "start": 422, "end": 427, "id": 72}, {"text": "of", "start": 428, "end": 430, "id": 73}, {"text": "1:8", "start": 431, "end": 434, "id": 74}, {"text": "to", "start": 435, "end": 437, "id": 75}, {"text": "1:32", "start": 438, "end": 442, "id": 76}, {"text": ".", "start": 442, "end": 443, "id": 77}]}
{"pdf_hash": "24913f77f80a54f95c9214000f23c5114f83dcc7", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Focal lesion seen on transrectal ultrasound (TRUS) and prostate magnetic resonance imaging in a 55-year-old man. (A) TRUS shows low echoic nodular lesion in left peripheral zone (arrow). TRUS guided biopsy for this lesion confirmed that the lesion was prostate cancer. (B) T2 weighted axial magnetic resonance scan shows relatively well defined nodular lesion in left peripheral zone (arrow). (C) Apparent diffusion coefficient map shows signal drop at the same lesion, which suggest diffusion restriction (arrow).", "width": 1378, "height": 396, "subcaptions": {"a": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "b": [56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78], "c": [79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101]}, "subfigures": [{"id": "b345d46f-f571-44af-aea4-6a04bfe33a82", "label": "a", "points": [[499.7, 352.3], [499.7, 8.4], [3.4, 8.4], [3.4, 352.3]], "color": "yellow"}, {"id": "a08ac2c7-05cf-4aa6-9dcb-f3baf4c72b85", "label": "b", "points": [[515, 1.8], [515, 356.7], [935.1, 356.7], [935.1, 1.8]], "color": "cyan"}, {"id": "eb5743b3-ae16-4fa6-ac1d-34c57e56d50e", "label": "c", "points": [[952.5, 6.2], [952.5, 361], [1370.5, 361], [1370.5, 6.2]], "color": "magenta"}], "tokens": [{"text": "Fig", 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{"pdf_hash": "2b721c4d92c6854fbd03a38a1fb8d613036975b0", "fig_key": "Figure9", "fig_uri": "8-Figure9-1.png", "text": "Fig 9. A 61 year old female with a 3.2 cm hypoechoic nodule seen in the right lobe on transverse image (a) that has markedly increased blood flow on color Doppler (b), a very stiff nodular component on strain elastography (c). On 2D-SWE (d) the nodule within the lesion had a stiffness value of 7.0m/s while the majority of the lesion has a stiffness of 2.28m/s. 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{"pdf_hash": "ea0fec464193cac1aae4d5cbe2c6da619090b092", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1. Chest X-rays: on the initial medical examination (a) and after chest tube drainage (b). Computed tomography scans: before the operation (c, d), after the operation (e), and after 3 cycles of pembrolizumab (f). 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{"pdf_hash": "49c52fce89e029c0493c7eeec7fc410f7b5bdb79", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3: (a) T1 axial magnetic resonance imaging (MRI) with contrast revealing an enhancing mass in the left atrium. (b) T1 sagittal MRI with contrast showing an enhancing mass in fourth ventricle b a", "width": 674, "height": 352, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41]}, "subfigures": [{"id": "e8a0e607-00ba-48f4-adc7-881b19042907", "label": "a", "points": [[1.1, 3.2], [1.1, 323.7], [334.3, 323.7], [334.3, 3.2]], "color": "yellow"}, {"id": "aece2d27-b899-49ba-8c3f-67b7bff07d29", "label": "b", "points": [[337.5, 323.7], [337.5, 3.2], [668.7, 3.2], [668.7, 323.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "T1", "start": 14, "end": 16, "id": 6}, {"text": "axial", "start": 17, "end": 22, "id": 7}, {"text": "magnetic", "start": 23, "end": 31, "id": 8}, {"text": "resonance", "start": 32, "end": 41, "id": 9}, {"text": "imaging", "start": 42, "end": 49, "id": 10}, {"text": "(", "start": 50, "end": 51, "id": 11}, {"text": "MRI", "start": 51, "end": 54, "id": 12}, {"text": ")", "start": 54, "end": 55, "id": 13}, {"text": "with", "start": 56, "end": 60, "id": 14}, {"text": "contrast", "start": 61, "end": 69, "id": 15}, {"text": "revealing", "start": 70, "end": 79, "id": 16}, {"text": "an", "start": 80, "end": 82, "id": 17}, {"text": "enhancing", "start": 83, "end": 92, "id": 18}, {"text": "mass", "start": 93, "end": 97, "id": 19}, {"text": "in", "start": 98, "end": 100, "id": 20}, {"text": "the", "start": 101, "end": 104, "id": 21}, {"text": "left", "start": 105, "end": 109, "id": 22}, {"text": "atrium", "start": 110, "end": 116, "id": 23}, {"text": ".", "start": 116, "end": 117, "id": 24}, {"text": "(", "start": 118, "end": 119, "id": 25}, {"text": "b", "start": 119, "end": 120, "id": 26}, {"text": ")", "start": 120, "end": 121, "id": 27}, {"text": "T1", "start": 122, "end": 124, "id": 28}, {"text": "sagittal", "start": 125, "end": 133, "id": 29}, {"text": "MRI", "start": 134, "end": 137, "id": 30}, {"text": "with", "start": 138, "end": 142, "id": 31}, {"text": "contrast", "start": 143, "end": 151, "id": 32}, {"text": "showing", "start": 152, "end": 159, "id": 33}, {"text": "an", "start": 160, "end": 162, "id": 34}, {"text": "enhancing", "start": 163, "end": 172, "id": 35}, {"text": "mass", "start": 173, "end": 177, "id": 36}, {"text": "in", "start": 178, "end": 180, "id": 37}, {"text": "fourth", "start": 181, "end": 187, "id": 38}, {"text": "ventricle", "start": 188, "end": 197, "id": 39}, {"text": "b", "start": 198, "end": 199, "id": 40}, {"text": "a", "start": 200, "end": 201, "id": 41}]}
{"pdf_hash": "45ecc10f0bdd69f84b15ba69c4ed4d3e7aca5595", "fig_key": "Figure9", "fig_uri": "7-Figure9-1.png", "text": "Fig. 9 a, b CECT in axial and coronal sections show infected right inguinal hernia mesh repair with collections (arrows) and sinus tracks (arrowhead). Culture yielded Mycobacterium chelonae. c Coronal plain CT in another patient shows soft tissue thickening and collection along the mesh tackers (arrow). d Laparoscopic retrieval of infected mesh (arrow) which was covered with pus and granulation tissue", "width": 848, "height": 722, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "c": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "d": [64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "11549460-e1e3-42f9-9a23-3dfb82cf28dd", "label": "a", "points": [[30.9, 22.6], [30.9, 352.1], [418, 352.1], [418, 22.6]], "color": "yellow"}, {"id": "dc04efbb-1b7e-44ff-aab4-39fe2c86b0f2", "label": "b", "points": [[428.7, 22.6], [428.7, 350.8], [811.8, 350.8], [811.8, 22.6]], "color": 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{"pdf_hash": "d9dfcdd6a1718df747373b3ad38c90b57fe262a6", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Reconstructed slices of a grating-based, multimodal CT scan of a biological sample (a formalin fixated infant mouse). Shown are sagittal (top row) and axial (bottom row) slices. The reconstruction yields quantitative values of linear attenuation coe cient \u00b5 (a), refractive index decrement (b, c) and linear di\u21b5usion coe cient \u270f (d). For the phase image (c), an iterative reconstruction scheme [20] was used instead of conventional FBP reconstruction in order to reduce stripe artifacts and noise. 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{"pdf_hash": "955a8a6f41d9a7752e76a402573c44e9287d66a8", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Figure 4: CT angiogram demonstrating the evolution of an acute thrombus to an intravascular chronic \u201cweb\u201d in the proximal right descending PA at the level of the right middle lobe take-off. The time interval between the left (A) and right (B) images is 1 year.", "width": 680, "height": 336, "subcaptions": {"a": [42, 43, 44, 45], "b": [47, 48, 49, 50]}, "subfigures": [{"id": "bc804b63-b5ed-4519-b09c-575d8b3b0118", "label": "a", "points": [[4.5, 0.4], [4.5, 309.7], [338.6, 309.7], [338.6, 0.4]], "color": "yellow"}, {"id": "bece3259-6cec-4bee-a96a-223d003d30fb", "label": "b", "points": [[342.9, 2.5], [342.9, 303.3], [675.9, 303.3], [675.9, 2.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "angiogram", "start": 13, "end": 22, "id": 4}, {"text": "demonstrating", "start": 23, "end": 36, "id": 5}, {"text": "the", "start": 37, "end": 40, "id": 6}, {"text": "evolution", "start": 41, "end": 50, "id": 7}, {"text": "of", "start": 51, "end": 53, "id": 8}, {"text": "an", "start": 54, "end": 56, "id": 9}, {"text": "acute", "start": 57, "end": 62, "id": 10}, {"text": "thrombus", "start": 63, "end": 71, "id": 11}, {"text": "to", "start": 72, "end": 74, "id": 12}, {"text": "an", "start": 75, "end": 77, "id": 13}, {"text": "intravascular", "start": 78, "end": 91, "id": 14}, {"text": "chronic", "start": 92, "end": 99, "id": 15}, {"text": "\u201c", "start": 100, "end": 101, "id": 16}, {"text": "web", "start": 101, "end": 104, "id": 17}, {"text": "\u201d", "start": 104, "end": 105, "id": 18}, {"text": "in", "start": 106, "end": 108, "id": 19}, {"text": "the", "start": 109, "end": 112, "id": 20}, {"text": "proximal", "start": 113, "end": 121, "id": 21}, {"text": "right", "start": 122, "end": 127, "id": 22}, {"text": "descending", "start": 128, "end": 138, "id": 23}, {"text": "PA", "start": 139, "end": 141, "id": 24}, {"text": "at", "start": 142, "end": 144, "id": 25}, {"text": "the", "start": 145, "end": 148, "id": 26}, {"text": "level", "start": 149, "end": 154, "id": 27}, {"text": "of", "start": 155, "end": 157, "id": 28}, {"text": "the", "start": 158, "end": 161, "id": 29}, {"text": "right", "start": 162, "end": 167, "id": 30}, {"text": "middle", "start": 168, "end": 174, "id": 31}, {"text": "lobe", "start": 175, "end": 179, "id": 32}, {"text": "take", "start": 180, "end": 184, "id": 33}, {"text": "-", "start": 184, "end": 185, "id": 34}, {"text": "off", "start": 185, "end": 188, "id": 35}, {"text": ".", "start": 188, "end": 189, "id": 36}, {"text": "The", "start": 190, "end": 193, "id": 37}, {"text": "time", "start": 194, "end": 198, "id": 38}, {"text": "interval", "start": 199, "end": 207, "id": 39}, {"text": "between", "start": 208, "end": 215, "id": 40}, {"text": "the", "start": 216, "end": 219, "id": 41}, {"text": "left", "start": 220, "end": 224, "id": 42}, {"text": "(", "start": 225, "end": 226, "id": 43}, {"text": "A", "start": 226, "end": 227, "id": 44}, {"text": ")", "start": 227, "end": 228, "id": 45}, {"text": "and", "start": 229, "end": 232, "id": 46}, {"text": "right", "start": 233, "end": 238, "id": 47}, {"text": "(", "start": 239, "end": 240, "id": 48}, {"text": "B", "start": 240, "end": 241, "id": 49}, {"text": ")", "start": 241, "end": 242, "id": 50}, {"text": "images", "start": 243, "end": 249, "id": 51}, {"text": "is", "start": 250, "end": 252, "id": 52}, {"text": "1", "start": 253, "end": 254, "id": 53}, {"text": "year", "start": 255, "end": 259, "id": 54}, {"text": ".", "start": 259, "end": 260, "id": 55}]}
{"pdf_hash": "a62daf8ff05bf2d3a3a1afe76bb16c167ed3a948", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Pedigree and brain MRI. (A) Pedigree of the family. Black symbol \u00bc affected with spastic ataxia and optic atrophy; grey symbol \u00bc affected with tremor; square \u00bc male; circle \u00bc female; diamond \u00bc masked gender (for anonymization purposes); diagonal line \u00bc deceased. (B and C) Brain MRI of patient III-5 at age 63: (B) Coronal T2 image showing optical atrophy (arrows), and (C) midsagittal T1 image showing mild atrophy of the superior vermis (arrow).", "width": 874, "height": 922, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56], "b": [57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82], "c": [57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101]}, "subfigures": [{"id": "3e315ecb-ba5e-40e7-a07d-61a41d696ad3", "label": "a", "points": [[10.4, 2.5], [10.4, 477.5], [851.2, 477.5], [851.2, 2.5]], "color": "yellow"}, {"id": "5c97f7b7-1938-4bca-a413-0bceb65cca3c", "label": "b", "points": [[3.5, 500.9], [3.5, 913.8], [424.6, 913.8], [424.6, 500.9]], "color": "cyan"}, 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{"pdf_hash": "cf9af6e6f2bc1de37022f06dc5049423a4125eb7", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4 \u2013 Dual-mode strain elastography. Dual-mode strain elastography imaging simultaneously displays the acoustic properties in a standard B-mode image (A) and the elastic properties in an elastogram (B); a color overlay on top of the B-mode image that represents tissue elasticity. As shown in the elastography color bar (left), current practice depicts red regions as tissue that is more elastic (less stiff) than blue regions. 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{"pdf_hash": "48a8b533ececb9d390f38477ecb5958dc0a9fa00", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Molar pregnancy in a 24-year-old woman. (A) Perpendicular to the endometrial line T2-weighted MR image of the pelvis showing a snowstorm appearance. 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{"pdf_hash": "f30bd42011584850f1b07a1bce7e29b8ec6d4da2", "fig_key": "Figure9", "fig_uri": "7-Figure9-1.png", "text": "Figure 9: Sacral plasmocytoma. MR: (a) Sagittal T1-WI shows homogenous mass involving S1, S2 and S3 with intermediate signal intensity. (b) Sagittal T2-WI show a high signal intensity of the mass extending into the pelvis, epidural space, and posterior elements.", "width": 976, "height": 652, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "43d575b0-9054-4598-95fc-c0c1304fe958", "label": "a", "points": [[36.3, 2.8], [36.3, 616.5], [475.7, 616.5], [475.7, 2.8]], "color": "yellow"}, {"id": "103c5bbc-6369-45a2-a121-db4e80a37282", "label": "b", "points": [[488, -0.3], [488, 614.9], [939.8, 614.9], [939.8, -0.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "9", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Sacral", "start": 10, "end": 16, "id": 3}, {"text": "plasmocytoma", "start": 17, "end": 29, "id": 4}, {"text": ".", "start": 29, "end": 30, "id": 5}, {"text": "MR", "start": 31, "end": 33, "id": 6}, {"text": ":", "start": 33, "end": 34, "id": 7}, {"text": "(", "start": 35, "end": 36, "id": 8}, {"text": "a", "start": 36, "end": 37, "id": 9}, {"text": ")", "start": 37, "end": 38, "id": 10}, {"text": "Sagittal", "start": 39, "end": 47, "id": 11}, {"text": "T1-WI", "start": 48, "end": 53, "id": 12}, {"text": "shows", "start": 54, "end": 59, "id": 13}, {"text": "homogenous", "start": 60, "end": 70, "id": 14}, {"text": "mass", "start": 71, "end": 75, "id": 15}, {"text": "involving", "start": 76, "end": 85, "id": 16}, {"text": "S1", "start": 86, "end": 88, "id": 17}, {"text": ",", "start": 88, "end": 89, "id": 18}, {"text": "S2", "start": 90, "end": 92, "id": 19}, {"text": "and", "start": 93, "end": 96, "id": 20}, {"text": "S3", "start": 97, "end": 99, "id": 21}, {"text": "with", "start": 100, "end": 104, "id": 22}, {"text": "intermediate", "start": 105, "end": 117, "id": 23}, {"text": "signal", "start": 118, "end": 124, "id": 24}, {"text": "intensity", "start": 125, "end": 134, "id": 25}, {"text": ".", "start": 134, "end": 135, "id": 26}, {"text": "(", "start": 136, "end": 137, "id": 27}, {"text": "b", "start": 137, "end": 138, "id": 28}, {"text": ")", "start": 138, "end": 139, "id": 29}, {"text": "Sagittal", "start": 140, "end": 148, "id": 30}, {"text": "T2-WI", "start": 149, "end": 154, "id": 31}, {"text": "show", "start": 155, "end": 159, "id": 32}, {"text": "a", "start": 160, "end": 161, "id": 33}, {"text": "high", "start": 162, "end": 166, "id": 34}, {"text": "signal", "start": 167, "end": 173, "id": 35}, {"text": "intensity", "start": 174, "end": 183, "id": 36}, {"text": "of", "start": 184, "end": 186, "id": 37}, {"text": "the", "start": 187, "end": 190, "id": 38}, {"text": "mass", "start": 191, "end": 195, "id": 39}, {"text": "extending", "start": 196, "end": 205, "id": 40}, {"text": "into", "start": 206, "end": 210, "id": 41}, {"text": "the", "start": 211, "end": 214, "id": 42}, {"text": "pelvis", "start": 215, "end": 221, "id": 43}, {"text": ",", "start": 221, "end": 222, "id": 44}, {"text": "epidural", "start": 223, "end": 231, "id": 45}, {"text": "space", "start": 232, "end": 237, "id": 46}, {"text": ",", "start": 237, "end": 238, "id": 47}, {"text": "and", "start": 239, "end": 242, "id": 48}, {"text": "posterior", "start": 243, "end": 252, "id": 49}, {"text": "elements", "start": 253, "end": 261, "id": 50}, {"text": ".", "start": 261, "end": 262, "id": 51}]}
{"pdf_hash": "642fdf54c657e9ebf87b15c12c36a639806dc233", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. CT-scan showing the intralobar sequestration in the left lower lobe with an anomalous aortic branch in case 1 (a) and case (b). CT, computed tomography.", "width": 666, "height": 1158, "subcaptions": {"a": [22, 23, 24, 25, 26], "b": [28, 29, 30, 31]}, "subfigures": [{"id": "e0f98f88-1d8a-45a6-899c-0640fc5a7f68", "label": "a", "points": [[3.2, 1.9], [3.2, 623.7], [661.8, 623.7], [661.8, 1.9]], "color": "yellow"}, {"id": "b6ce9f18-e985-4938-85bf-bf1d275ec1b6", "label": "b", "points": [[4.2, 630.5], [4.2, 1136.6], [658.6, 1136.6], [658.6, 630.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "CT", "start": 8, "end": 10, "id": 4}, {"text": "-", "start": 10, "end": 11, "id": 5}, {"text": "scan", "start": 11, "end": 15, "id": 6}, {"text": "showing", "start": 16, "end": 23, "id": 7}, {"text": "the", "start": 24, "end": 27, "id": 8}, {"text": "intralobar", "start": 28, "end": 38, "id": 9}, {"text": "sequestration", "start": 39, "end": 52, "id": 10}, {"text": "in", "start": 53, "end": 55, "id": 11}, {"text": "the", "start": 56, "end": 59, "id": 12}, {"text": "left", "start": 60, "end": 64, "id": 13}, {"text": "lower", "start": 65, "end": 70, "id": 14}, {"text": "lobe", "start": 71, "end": 75, "id": 15}, {"text": "with", "start": 76, "end": 80, "id": 16}, {"text": "an", "start": 81, "end": 83, "id": 17}, {"text": "anomalous", "start": 84, "end": 93, "id": 18}, {"text": "aortic", "start": 94, "end": 100, "id": 19}, {"text": "branch", "start": 101, "end": 107, "id": 20}, {"text": "in", "start": 108, "end": 110, "id": 21}, {"text": "case", "start": 111, "end": 115, "id": 22}, {"text": "1", "start": 116, "end": 117, "id": 23}, {"text": "(", "start": 118, "end": 119, "id": 24}, {"text": "a", "start": 119, "end": 120, "id": 25}, {"text": ")", "start": 120, "end": 121, "id": 26}, {"text": "and", "start": 122, "end": 125, "id": 27}, {"text": "case", "start": 126, "end": 130, "id": 28}, {"text": "(", "start": 131, "end": 132, "id": 29}, {"text": "b", "start": 132, "end": 133, "id": 30}, {"text": ")", "start": 133, "end": 134, "id": 31}, {"text": ".", "start": 134, "end": 135, "id": 32}, {"text": "CT", "start": 136, "end": 138, "id": 33}, {"text": ",", "start": 138, "end": 139, "id": 34}, {"text": "computed", "start": 140, "end": 148, "id": 35}, {"text": "tomography", "start": 149, "end": 159, "id": 36}, {"text": ".", "start": 159, "end": 160, "id": 37}]}
{"pdf_hash": "4d11a69a9bbf35c197f8bbd3ab1a4d61693dce10", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "Fig. 4 A 64-year-old male with moderately differentiated adenocarcinoma of the appendix (case 4). The coronal (a) and axial (b) contrastenhanced CT scan images reveal a dilated, fluid-filled appendix with mural thickening and enhancement (white arrows). There is also evidence of periappendiceal inflammatory fat stranding (white asterisk) which is best appreciated in the axial image", "width": 578, "height": 1090, "subcaptions": {"a": [21, 22, 23, 24], "b": [26, 27, 28, 29]}, "subfigures": [{"id": "a63fe19e-2462-41d7-b739-00bb2e223574", "label": "a", "points": [[35, 34.3], [35, 666.3], [544, 666.3], [544, 34.3]], "color": "yellow"}, {"id": "604c4c90-1483-4ee9-8a96-22224a70024a", "label": "b", "points": [[34, 685.3], [34, 1059.4], [540, 1059.4], [540, 685.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": "64-year", "start": 9, "end": 16, "id": 4}, {"text": "-", "start": 16, "end": 17, "id": 5}, {"text": "old", "start": 17, "end": 20, "id": 6}, {"text": "male", "start": 21, "end": 25, "id": 7}, {"text": "with", "start": 26, "end": 30, "id": 8}, {"text": "moderately", "start": 31, "end": 41, "id": 9}, {"text": "differentiated", "start": 42, "end": 56, "id": 10}, {"text": "adenocarcinoma", "start": 57, "end": 71, "id": 11}, {"text": "of", "start": 72, "end": 74, "id": 12}, {"text": "the", "start": 75, "end": 78, "id": 13}, {"text": "appendix", "start": 79, "end": 87, "id": 14}, {"text": "(", "start": 88, "end": 89, "id": 15}, {"text": "case", "start": 89, "end": 93, "id": 16}, {"text": "4", "start": 94, "end": 95, "id": 17}, {"text": ")", "start": 95, "end": 96, "id": 18}, {"text": ".", "start": 96, "end": 97, "id": 19}, {"text": "The", "start": 98, "end": 101, "id": 20}, {"text": "coronal", "start": 102, "end": 109, "id": 21}, {"text": "(", "start": 110, "end": 111, "id": 22}, {"text": "a", "start": 111, "end": 112, "id": 23}, {"text": ")", "start": 112, "end": 113, "id": 24}, {"text": "and", "start": 114, "end": 117, "id": 25}, {"text": "axial", "start": 118, "end": 123, "id": 26}, {"text": "(", "start": 124, "end": 125, "id": 27}, {"text": "b", "start": 125, "end": 126, "id": 28}, {"text": ")", "start": 126, "end": 127, "id": 29}, {"text": "contrastenhanced", "start": 128, "end": 144, "id": 30}, {"text": "CT", "start": 145, "end": 147, "id": 31}, {"text": "scan", "start": 148, "end": 152, "id": 32}, {"text": "images", "start": 153, "end": 159, "id": 33}, {"text": "reveal", "start": 160, "end": 166, "id": 34}, {"text": "a", "start": 167, "end": 168, "id": 35}, {"text": "dilated", "start": 169, "end": 176, "id": 36}, {"text": ",", "start": 176, "end": 177, "id": 37}, {"text": "fluid", "start": 178, "end": 183, "id": 38}, {"text": "-", "start": 183, "end": 184, "id": 39}, {"text": "filled", "start": 184, "end": 190, "id": 40}, {"text": "appendix", "start": 191, "end": 199, "id": 41}, {"text": "with", "start": 200, "end": 204, "id": 42}, {"text": "mural", "start": 205, "end": 210, "id": 43}, {"text": "thickening", "start": 211, "end": 221, "id": 44}, {"text": "and", "start": 222, "end": 225, "id": 45}, {"text": "enhancement", "start": 226, "end": 237, "id": 46}, {"text": "(", "start": 238, "end": 239, "id": 47}, {"text": "white", "start": 239, "end": 244, "id": 48}, {"text": "arrows", "start": 245, "end": 251, "id": 49}, {"text": ")", "start": 251, "end": 252, "id": 50}, {"text": ".", "start": 252, "end": 253, "id": 51}, {"text": "There", "start": 254, "end": 259, "id": 52}, {"text": "is", "start": 260, "end": 262, "id": 53}, {"text": "also", "start": 263, "end": 267, "id": 54}, {"text": "evidence", "start": 268, "end": 276, "id": 55}, {"text": "of", "start": 277, "end": 279, "id": 56}, {"text": "periappendiceal", "start": 280, "end": 295, "id": 57}, {"text": "inflammatory", "start": 296, "end": 308, "id": 58}, {"text": "fat", "start": 309, "end": 312, "id": 59}, {"text": "stranding", "start": 313, "end": 322, "id": 60}, {"text": "(", "start": 323, "end": 324, "id": 61}, {"text": "white", "start": 324, "end": 329, "id": 62}, {"text": "asterisk", "start": 330, "end": 338, "id": 63}, {"text": ")", "start": 338, "end": 339, "id": 64}, {"text": "which", "start": 340, "end": 345, "id": 65}, {"text": "is", "start": 346, "end": 348, "id": 66}, {"text": "best", "start": 349, "end": 353, "id": 67}, {"text": "appreciated", "start": 354, "end": 365, "id": 68}, {"text": "in", "start": 366, "end": 368, "id": 69}, {"text": "the", "start": 369, "end": 372, "id": 70}, {"text": "axial", "start": 373, "end": 378, "id": 71}, {"text": "image", "start": 379, "end": 384, "id": 72}]}
{"pdf_hash": "cda6423050434bd20409f61af7e56dc327412231", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. 55 years old male, initial simple X-rays shows nonspecific findings except mild degenerative changes. (A) MRI shows mild compression of cecal sac at Lt. lateral space and minimal fluid signal intensity adjacent Lt. L3 with preserved adjacent intervertebral disc spaces. (B) Successful healing process is observed after HD # 6 months.", "width": 1340, "height": 510, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "c": [0]}, "subfigures": [{"id": "efeddce7-4691-4cbd-a98b-d15674230cfb", "label": "a", "points": [[5.4, 3.9], [5.4, 486.5], [426.6, 486.5], [426.6, 3.9]], "color": "yellow"}, {"id": "a0c318c6-f8b6-4f00-a65f-152aeeb13cec", "label": "b", "points": [[443.6, 1.8], [443.6, 492.9], [881.8, 492.9], [881.8, 1.8]], "color": "cyan"}, {"id": "704edcb6-2541-4dd7-8c1f-669362645d97", "label": "c", "points": [[896.6, 3.9], [896.6, 490.8], [1336.9, 490.8], [1336.9, 3.9]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "55", "start": 8, "end": 10, "id": 4}, {"text": "years", "start": 11, "end": 16, "id": 5}, {"text": "old", "start": 17, "end": 20, "id": 6}, {"text": "male", "start": 21, "end": 25, "id": 7}, {"text": ",", "start": 25, "end": 26, "id": 8}, {"text": "initial", "start": 27, "end": 34, "id": 9}, {"text": "simple", "start": 35, "end": 41, "id": 10}, {"text": "X", "start": 42, "end": 43, "id": 11}, {"text": "-", "start": 43, "end": 44, "id": 12}, {"text": "rays", "start": 44, "end": 48, "id": 13}, {"text": "shows", "start": 49, "end": 54, "id": 14}, {"text": "nonspecific", "start": 55, "end": 66, "id": 15}, {"text": "findings", "start": 67, "end": 75, "id": 16}, {"text": "except", "start": 76, "end": 82, "id": 17}, {"text": "mild", "start": 83, "end": 87, "id": 18}, {"text": "degenerative", "start": 88, "end": 100, "id": 19}, {"text": "changes", "start": 101, "end": 108, "id": 20}, {"text": ".", "start": 108, "end": 109, "id": 21}, {"text": "(", "start": 110, "end": 111, "id": 22}, {"text": "A", "start": 111, "end": 112, "id": 23}, {"text": ")", "start": 112, "end": 113, "id": 24}, {"text": "MRI", "start": 114, "end": 117, "id": 25}, {"text": "shows", "start": 118, "end": 123, "id": 26}, {"text": "mild", "start": 124, "end": 128, "id": 27}, {"text": "compression", "start": 129, "end": 140, "id": 28}, {"text": "of", "start": 141, "end": 143, "id": 29}, {"text": "cecal", "start": 144, "end": 149, "id": 30}, {"text": "sac", "start": 150, "end": 153, "id": 31}, {"text": "at", "start": 154, "end": 156, "id": 32}, {"text": "Lt", "start": 157, "end": 159, "id": 33}, {"text": ".", "start": 159, "end": 160, "id": 34}, {"text": "lateral", "start": 161, "end": 168, "id": 35}, {"text": "space", "start": 169, "end": 174, "id": 36}, {"text": "and", "start": 175, "end": 178, "id": 37}, {"text": "minimal", "start": 179, "end": 186, "id": 38}, {"text": "fluid", "start": 187, "end": 192, "id": 39}, {"text": "signal", "start": 193, "end": 199, "id": 40}, {"text": "intensity", "start": 200, "end": 209, "id": 41}, {"text": "adjacent", "start": 210, "end": 218, "id": 42}, {"text": "Lt", "start": 219, "end": 221, "id": 43}, {"text": ".", "start": 221, "end": 222, "id": 44}, {"text": "L3", "start": 223, "end": 225, "id": 45}, {"text": "with", "start": 226, "end": 230, "id": 46}, {"text": "preserved", "start": 231, "end": 240, "id": 47}, {"text": "adjacent", "start": 241, "end": 249, "id": 48}, {"text": "intervertebral", "start": 250, "end": 264, "id": 49}, {"text": "disc", "start": 265, "end": 269, "id": 50}, {"text": "spaces", "start": 270, "end": 276, "id": 51}, {"text": ".", "start": 276, "end": 277, "id": 52}, {"text": "(", "start": 278, "end": 279, "id": 53}, {"text": "B", "start": 279, "end": 280, "id": 54}, {"text": ")", "start": 280, "end": 281, "id": 55}, {"text": "Successful", "start": 282, "end": 292, "id": 56}, {"text": "healing", "start": 293, "end": 300, "id": 57}, {"text": "process", "start": 301, "end": 308, "id": 58}, {"text": "is", "start": 309, "end": 311, "id": 59}, {"text": "observed", "start": 312, "end": 320, "id": 60}, {"text": "after", "start": 321, "end": 326, "id": 61}, {"text": "HD", "start": 327, "end": 329, "id": 62}, {"text": "#", "start": 330, "end": 331, "id": 63}, {"text": "6", "start": 332, "end": 333, "id": 64}, {"text": "months", "start": 334, "end": 340, "id": 65}, {"text": ".", "start": 340, "end": 341, "id": 66}]}
{"pdf_hash": "f0c61d557d8a7a2e1b842d7683a66753a069210a", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4. Cytoskeletal inhibitors reverse raft aggregation at signalincompetent NK immune synapses. For each effector\u035etarget cell pair, Nomarski imaging is shown to the left of fluorescence (original magnification \u03eb160). NK cell lipid rafts are visible as Alexa 568-conjugated CTX \u2424 staining (red), and target cells express HLA-Cw4-GFP (green). (A) YTS\u035eKIR2DL1(Y377S,Y407S) and 721.221\u035eHLA-Cw4-GFP, no drug treatment. (B) YTS\u035eKIR2DL1(Y377S,Y407S) cells pretreated with 10 M cytochalasin D before co-incubation with 721.221\u035eHLA-Cw4-GFP targets. Note that ligand clustering remains unperturbed, whereas rafts, which were polarized in the untreated sample, are dispersed. 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{"pdf_hash": "819ad95c5ce1f5fc3cc80abb5e501e60b5c00d57", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Figure 1 In vivo endoscopic ultrasound guided needle based confocal laser endomicroscopy, ex vivo confocal laser endomicroscopy, and histopathology of intraductal papillary mucinous neoplasms. Panels A, B and C are from subject 1 (gastric subtype with high grade dysplasia). Panels D, E, and F are from subject 2 (intestinal subtype with high grade dysplasia). Complete \u201cfingerlike\u201d papillae are observed in both in vivo and ex vivo CLE. The vascular core in ex vivo CLE imaging is better defined. 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{"pdf_hash": "b11928dbd6a930090440042291eed39ee00e6ce4", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. A neonatal excitotoxic lesion of the ventral hippocampus shown in a diagram adapted from the atlas of Paxinos and Watson (Paxinos and Watson 1986) (A) and in photomicrographs of Nissl-stained coronal brain sections through the hippocampus of an adult rat with a neonatal sham (B) and ibotenic acid lesion (C). A gray area in a diagram indicates the boundaries of a lesion. 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{"pdf_hash": "b8a84f21a4844a93654acd089662b5bbd6e11580", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Fig 3. The different steps for quantification of total adipose tissue by micro-computed tomography. Anesthetized mice are placed in a supine position in an imaging cell; three-dimensional x-ray images are acquired on the CT part of a \u03bcSPECT-\u03bcCT (eXplore speCZT Vision 120, GE, Waukesha, USA). Volumes are reconstructed with a voxel size equal to 100x100x100 \u03bcm 3 ; reconstructed images are filtered with a Gaussian filter to reduce noise. (a) Whole body scan. (b) Selection of whole body volume. (c) Choice of threshold level based on fat pad (FP). (d) Representation of total adipose tissue with subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT). 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{"pdf_hash": "78a12bc2a43936ccd50427ad8d09fbcb7281d127", "fig_key": "Figure9", "fig_uri": "6-Figure9-1.png", "text": "Figure 9: Fecal impaction: (a and b) Erect and supine plain abdominal radiograph in a 75\u2011year\u2011old man presenting with abdominal distension and worsening lower abdominal pain demonstrates dilatation of the large bowel loops. Computed tomography scan (c and d) performed subsequently demonstrates large amount of stool in the sigmoid colon and rectum (arrows) which resulted in large bowel dilatation. No mass was identified and the patient was managed conservatively with enemas. 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{"pdf_hash": "d78e348fab44894970ce5dcc1049724270806468", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: (a) A plain computed tomography (CT) scan (axial view) indicated vertebral artery injury. (b) An enhanced CT scan (coronal view) demonstrated left vertebral artery interruption", "width": 674, "height": 352, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38]}, "subfigures": [{"id": "7a594c0d-47dc-4f9a-92be-24dc8c0384c7", "label": "a", "points": [[2.7, 2], [2.7, 315], [332.8, 315], [332.8, 2]], "color": "yellow"}, {"id": "8e3d6e0f-6f15-44b2-a464-ffff3f90ba29", "label": "b", "points": [[343.4, 0.9], [343.4, 318.2], [670.3, 318.2], [670.3, 0.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "a", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "A", "start": 14, "end": 15, "id": 6}, {"text": "plain", "start": 16, "end": 21, "id": 7}, {"text": "computed", "start": 22, "end": 30, "id": 8}, {"text": "tomography", "start": 31, "end": 41, "id": 9}, {"text": "(", "start": 42, "end": 43, "id": 10}, {"text": "CT", "start": 43, "end": 45, "id": 11}, {"text": ")", "start": 45, "end": 46, "id": 12}, {"text": "scan", "start": 47, "end": 51, "id": 13}, {"text": "(", "start": 52, "end": 53, "id": 14}, {"text": "axial", "start": 53, "end": 58, "id": 15}, {"text": "view", "start": 59, "end": 63, "id": 16}, {"text": ")", "start": 63, "end": 64, "id": 17}, {"text": "indicated", "start": 65, "end": 74, "id": 18}, {"text": "vertebral", "start": 75, "end": 84, "id": 19}, {"text": "artery", "start": 85, "end": 91, "id": 20}, {"text": "injury", "start": 92, "end": 98, "id": 21}, {"text": ".", "start": 98, "end": 99, "id": 22}, {"text": "(", "start": 100, "end": 101, "id": 23}, {"text": "b", "start": 101, "end": 102, "id": 24}, {"text": ")", "start": 102, "end": 103, "id": 25}, {"text": "An", "start": 104, "end": 106, "id": 26}, {"text": "enhanced", "start": 107, "end": 115, "id": 27}, {"text": "CT", "start": 116, "end": 118, "id": 28}, {"text": "scan", "start": 119, "end": 123, "id": 29}, {"text": "(", "start": 124, "end": 125, "id": 30}, {"text": "coronal", "start": 125, "end": 132, "id": 31}, {"text": "view", "start": 133, "end": 137, "id": 32}, {"text": ")", "start": 137, "end": 138, "id": 33}, {"text": "demonstrated", "start": 139, "end": 151, "id": 34}, {"text": "left", "start": 152, "end": 156, "id": 35}, {"text": "vertebral", "start": 157, "end": 166, "id": 36}, {"text": "artery", "start": 167, "end": 173, "id": 37}, {"text": "interruption", "start": 174, "end": 186, "id": 38}]}
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{"pdf_hash": "c380d8a12eecf89890b69cfe84f58df8f0a41b0b", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. A 30-year-old female patient with giant cell tumor (GCT) of the left distal femur. (A) X-ray film reveals osteolytic destruction and cortical thinning at the left femoral condyle. (B) and (C) T1-weighted MRI reveals low signal at the distal femur and a lateral visible tumor penetrating the front side of the cortex. (D) 4 days after surgery, postoperative X-ray reveals bone cement filling and internal fixation are normal. 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{"pdf_hash": "1e47e26a24994c71e59f60dd0174ba263497ab44", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: MR imaging revealing a non-enhancing cystic-appearing lesion growing off the conus medullaris at L1- L2 in the spinal with hyperintensity on a sagittal T1-weighted image (a) and hypointensity on a T2-weighted image (b)", "width": 676, "height": 434, "subcaptions": {"a": [32, 33, 34, 26, 27, 28, 29, 30, 31], "b": [36, 37, 38, 39, 40, 41, 42, 43]}, "subfigures": [{"id": "4dd3fadc-71d2-4e79-8ca3-f53275dd6ee2", "label": "a", "points": [[2.1, 0], [2.1, 408], [337.5, 408], [337.5, 0]], "color": "yellow"}, {"id": "c35f53bc-aba4-49c6-b6ac-21c74fa163d5", "label": "b", "points": [[341.7, 1.1], [341.7, 406.9], [674.9, 406.9], [674.9, 1.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "MR", "start": 10, "end": 12, "id": 3}, {"text": "imaging", "start": 13, "end": 20, "id": 4}, {"text": "revealing", "start": 21, "end": 30, "id": 5}, {"text": "a", "start": 31, "end": 32, "id": 6}, {"text": "non", "start": 33, "end": 36, "id": 7}, {"text": "-", "start": 36, "end": 37, "id": 8}, {"text": "enhancing", "start": 37, "end": 46, "id": 9}, {"text": "cystic", "start": 47, "end": 53, "id": 10}, {"text": "-", "start": 53, "end": 54, "id": 11}, {"text": "appearing", "start": 54, "end": 63, "id": 12}, {"text": "lesion", "start": 64, "end": 70, "id": 13}, {"text": "growing", "start": 71, "end": 78, "id": 14}, {"text": "off", "start": 79, "end": 82, "id": 15}, {"text": "the", "start": 83, "end": 86, "id": 16}, {"text": "conus", "start": 87, "end": 92, "id": 17}, {"text": "medullaris", "start": 93, "end": 103, "id": 18}, {"text": "at", "start": 104, "end": 106, "id": 19}, {"text": "L1-", "start": 107, "end": 110, "id": 20}, {"text": "L2", "start": 111, "end": 113, "id": 21}, {"text": "in", "start": 114, "end": 116, "id": 22}, {"text": "the", "start": 117, "end": 120, "id": 23}, {"text": "spinal", "start": 121, "end": 127, "id": 24}, {"text": "with", "start": 128, "end": 132, "id": 25}, {"text": "hyperintensity", "start": 133, "end": 147, "id": 26}, {"text": "on", "start": 148, "end": 150, "id": 27}, {"text": "a", "start": 151, "end": 152, "id": 28}, {"text": "sagittal", "start": 153, "end": 161, "id": 29}, {"text": "T1-weighted", "start": 162, "end": 173, "id": 30}, {"text": "image", "start": 174, "end": 179, "id": 31}, {"text": "(", "start": 180, "end": 181, "id": 32}, {"text": "a", "start": 181, "end": 182, "id": 33}, {"text": ")", "start": 182, "end": 183, "id": 34}, {"text": "and", "start": 184, "end": 187, "id": 35}, {"text": "hypointensity", "start": 188, "end": 201, "id": 36}, {"text": "on", "start": 202, "end": 204, "id": 37}, {"text": "a", "start": 205, "end": 206, "id": 38}, {"text": "T2-weighted", "start": 207, "end": 218, "id": 39}, {"text": "image", "start": 219, "end": 224, "id": 40}, {"text": "(", "start": 225, "end": 226, "id": 41}, {"text": "b", "start": 226, "end": 227, "id": 42}, {"text": ")", "start": 227, "end": 228, "id": 43}]}
{"pdf_hash": "81f6de248df1b367e289c926617fa2b5e6e1bde6", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 Fundus examination. a Peripheral schisis with a large hole can be noticed in the retinography of the right eye. b OCT B-scan across the fovea. Intraretinal cysts can be observed along the inner nuclear layer. c Three-dimensional reconstruction across the hole in the peripheral schisis of the inferior retina. 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{"pdf_hash": "800baa15939c8548d6c356a6965061a6b58a4617", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2 New ASPSCR1-TFE3 renal cell carcinomas with t(X;17)(p11;q25). (a\u2013e) H& E-stained sections of nested pseudopapillary growth pattern featuring dyscohesive cells with voluminous cytoplasm. (f) Strong, nuclear labeling for TFE3 protein.", "width": 1368, "height": 1550, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "b": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "c": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "d": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "e": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33], "f": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "7992af5b-a69b-4eee-8e61-43539912baff", "label": "a", "points": [[31.3, 6.5], [31.3, 490.6], [684, 490.6], [684, 6.5]], "color": "yellow"}, {"id": "3cb4b54d-ac1f-4234-ac65-fe20d6df3493", "label": "f", "points": [[697, 1015.8], [697, 1521.5], [1351.8, 1521.5], [1351.8, 1015.8]], "color": "deepskyblue"}, {"id": "18f93e1f-384c-46a3-9011-714c8e315541", "label": "b", "points": [[703.5, 4.3], [703.5, 492.7], [1354, 492.7], [1354, 4.3]], "color": "cyan"}, {"id": "0f87f58f-e4e0-46c1-ac3f-d368ee5b1aac", "label": "c", "points": [[29.2, 514.4], [29.2, 1004.9], [681.9, 1004.9], [681.9, 514.4]], "color": "magenta"}, {"id": "9dbda583-1381-412a-a3ac-e0b8123cb6e3", "label": "d", "points": [[701.3, 510], [701.3, 1002.8], [1347.5, 1002.8], [1347.5, 510]], "color": "springgreen"}, {"id": "586faff9-d3df-4e15-8189-0868923b68a6", "label": "e", "points": [[27, 1017.9], [27, 1523.6], [681.9, 1523.6], [681.9, 1017.9]], "color": "tomato"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "New", "start": 9, "end": 12, "id": 2}, {"text": "ASPSCR1-TFE3", "start": 13, "end": 25, "id": 3}, {"text": "renal", "start": 26, "end": 31, "id": 4}, {"text": "cell", "start": 32, "end": 36, "id": 5}, {"text": "carcinomas", "start": 37, "end": 47, "id": 6}, {"text": "with", "start": 48, "end": 52, "id": 7}, {"text": "t(X;17)(p11;q25", "start": 53, "end": 68, "id": 8}, {"text": ")", "start": 68, "end": 69, "id": 9}, {"text": ".", "start": 69, "end": 70, "id": 10}, {"text": "(", "start": 71, "end": 72, "id": 11}, {"text": "a", "start": 72, "end": 73, "id": 12}, {"text": "\u2013", "start": 73, "end": 74, "id": 13}, {"text": "e", "start": 74, "end": 75, "id": 14}, {"text": ")", "start": 75, "end": 76, "id": 15}, {"text": "H", "start": 77, "end": 78, "id": 16}, {"text": "&", "start": 78, "end": 79, "id": 17}, {"text": "E", "start": 80, "end": 81, "id": 18}, {"text": "-", "start": 81, "end": 82, "id": 19}, {"text": "stained", "start": 82, "end": 89, "id": 20}, {"text": "sections", "start": 90, "end": 98, "id": 21}, {"text": "of", "start": 99, "end": 101, "id": 22}, {"text": "nested", "start": 102, "end": 108, "id": 23}, {"text": "pseudopapillary", "start": 109, "end": 124, "id": 24}, {"text": "growth", "start": 125, "end": 131, "id": 25}, {"text": "pattern", "start": 132, "end": 139, "id": 26}, {"text": "featuring", "start": 140, "end": 149, "id": 27}, {"text": "dyscohesive", "start": 150, "end": 161, "id": 28}, {"text": "cells", "start": 162, "end": 167, "id": 29}, {"text": "with", "start": 168, "end": 172, "id": 30}, {"text": "voluminous", "start": 173, "end": 183, "id": 31}, {"text": "cytoplasm", "start": 184, "end": 193, "id": 32}, {"text": ".", "start": 193, "end": 194, "id": 33}, {"text": "(", "start": 195, "end": 196, "id": 34}, {"text": "f", "start": 196, "end": 197, "id": 35}, {"text": ")", "start": 197, "end": 198, "id": 36}, {"text": "Strong", "start": 199, "end": 205, "id": 37}, {"text": ",", "start": 205, "end": 206, "id": 38}, {"text": "nuclear", "start": 207, "end": 214, "id": 39}, {"text": "labeling", "start": 215, "end": 223, "id": 40}, {"text": "for", "start": 224, "end": 227, "id": 41}, {"text": "TFE3", "start": 228, "end": 232, "id": 42}, {"text": "protein", "start": 233, "end": 240, "id": 43}, {"text": ".", "start": 240, "end": 241, "id": 44}]}
{"pdf_hash": "850541ca5c69c07bbd2ae286733ab99d04fec38c", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Abdominal CT, in the third year of D-penicillamine and zinc sulfate therapy, shows minimal heterogeneity of liver parenchyma (A), dilatation of portal vein and splenomegaly (B), but no nodular lesions.", "width": 1340, "height": 534, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27], "b": [32, 33, 34, 35, 36, 37, 29, 30, 31]}, "subfigures": [{"id": "f8c445ac-580e-4073-93d8-0964d8a7207b", "label": "a", "points": [[4.2, 0], [4.2, 495.4], [647.8, 495.4], [647.8, 0]], "color": "yellow"}, {"id": "06232710-f27b-4c6f-a792-c694845c5bef", "label": "b", "points": [[690.1, 499.6], [690.1, 4.2], [1337.9, 4.2], [1337.9, 499.6]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Abdominal", "start": 10, "end": 19, "id": 3}, {"text": "CT", "start": 20, "end": 22, "id": 4}, {"text": ",", "start": 22, "end": 23, "id": 5}, {"text": "in", "start": 24, "end": 26, "id": 6}, {"text": "the", "start": 27, "end": 30, "id": 7}, {"text": "third", "start": 31, "end": 36, "id": 8}, {"text": "year", "start": 37, "end": 41, "id": 9}, {"text": "of", "start": 42, "end": 44, "id": 10}, {"text": "D", "start": 45, "end": 46, "id": 11}, {"text": "-", "start": 46, "end": 47, "id": 12}, {"text": "penicillamine", "start": 47, "end": 60, "id": 13}, {"text": "and", "start": 61, "end": 64, "id": 14}, {"text": "zinc", "start": 65, "end": 69, "id": 15}, {"text": "sulfate", "start": 70, "end": 77, "id": 16}, {"text": "therapy", "start": 78, "end": 85, "id": 17}, {"text": ",", "start": 85, "end": 86, "id": 18}, {"text": "shows", "start": 87, "end": 92, "id": 19}, {"text": "minimal", "start": 93, "end": 100, "id": 20}, {"text": "heterogeneity", "start": 101, "end": 114, "id": 21}, {"text": "of", "start": 115, "end": 117, "id": 22}, {"text": "liver", "start": 118, "end": 123, "id": 23}, {"text": "parenchyma", "start": 124, "end": 134, "id": 24}, {"text": "(", "start": 135, "end": 136, "id": 25}, {"text": "A", "start": 136, "end": 137, "id": 26}, {"text": ")", "start": 137, "end": 138, "id": 27}, {"text": ",", "start": 138, "end": 139, "id": 28}, {"text": "dilatation", "start": 140, "end": 150, "id": 29}, {"text": "of", "start": 151, "end": 153, "id": 30}, {"text": "portal", "start": 154, "end": 160, "id": 31}, {"text": "vein", "start": 161, "end": 165, "id": 32}, {"text": "and", "start": 166, "end": 169, "id": 33}, {"text": "splenomegaly", "start": 170, "end": 182, "id": 34}, {"text": "(", "start": 183, "end": 184, "id": 35}, {"text": "B", "start": 184, "end": 185, "id": 36}, {"text": ")", "start": 185, "end": 186, "id": 37}, {"text": ",", "start": 186, "end": 187, "id": 38}, {"text": "but", "start": 188, "end": 191, "id": 39}, {"text": "no", "start": 192, "end": 194, "id": 40}, {"text": "nodular", "start": 195, "end": 202, "id": 41}, {"text": "lesions", "start": 203, "end": 210, "id": 42}, {"text": ".", "start": 210, "end": 211, "id": 43}]}
{"pdf_hash": "d04fd3646fffa0b2e07ebd556b4e85706ee8f6e1", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Photomicrographs of lamprey hindbrain and spinal cord. A: transverse section through the cerebellum and isthmus at the level of the trigeminal sensory and motor roots. B: transverse section through the medulla at the level of the trigeminal motor nucleus and descending trigeminal tract (outlined by dashed line). C: transverse section at an isthmal level showing the degenerating trigeminal sensory root. D: transverse section of the spinal cord showing the degenerating descending trigeminal tract in the dorsal funiculus. Bar scales equal 100 ~m. Magnifications of A and B are identical, as are magnifications of C and D. 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{"pdf_hash": "57902a6ced1a7326b341839bec6f9668eb6560d9", "fig_key": "Figure7", "fig_uri": "7-Figure7-1.png", "text": "Fig. 7 Plexiform neurofibroma. a Axial T1-weighted MR image demonstrates a mass that is iso\u2212/hypointense to muscle (arrows). b Axial T2-weighted MR image demonstrates numerous hyperintense masses involving the left carotid space (white arrows). The left internal carotid artery (i) is displaced posterolaterally. Note the characteristic \u201cfish-eye\u201d or \u201ctarget\u201d appearance of this lesion (black arrows). This patient had neurofibromatosis, and extensive transspatial neurofibromas can be seen in other portions of the neck (arrowheads)", "width": 652, "height": 1222, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95]}, "subfigures": [{"id": "df8016ce-3d0e-4972-8796-c5e8f83c79bc", "label": "a", "points": [[27.8, 11.2], [27.8, 399.4], [621.1, 399.4], [621.1, 11.2]], "color": "yellow"}, {"id": "a1dfd1d6-8ddd-408a-8acd-6aeded9dd5a5", "label": "b", "points": [[30.9, 407.7], [30.9, 1210], [621.1, 1210], [621.1, 407.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "7", "start": 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{"pdf_hash": "c136cb811526260f51acc31d3313e83657d466d5", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2: Colour scale brain perfusion SPECT analysis with 99mTx-HMPAO fused with CT scan for patient 1: (a) December 2017; (b) July 2018.", "width": 998, "height": 218, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32]}, "subfigures": [{"id": "855719c1-4084-4bc7-845a-a37514158611", "label": "a", "points": [[3.2, 1.6], [3.2, 149.8], [473, 149.8], [473, 1.6]], "color": "yellow"}, {"id": "2f9747fd-f406-4d80-b92e-df7ecf75f121", "label": "b", "points": [[498.2, 0], [498.2, 145.1], [966.5, 145.1], [966.5, 0]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Colour", "start": 10, "end": 16, "id": 3}, {"text": "scale", "start": 17, "end": 22, "id": 4}, {"text": "brain", "start": 23, "end": 28, "id": 5}, {"text": "perfusion", "start": 29, "end": 38, "id": 6}, {"text": "SPECT", "start": 39, "end": 44, "id": 7}, {"text": "analysis", "start": 45, "end": 53, "id": 8}, {"text": "with", "start": 54, "end": 58, "id": 9}, {"text": "99mTx", "start": 59, "end": 64, "id": 10}, {"text": "-", "start": 64, "end": 65, "id": 11}, {"text": "HMPAO", "start": 65, "end": 70, "id": 12}, {"text": "fused", "start": 71, "end": 76, "id": 13}, {"text": "with", "start": 77, "end": 81, "id": 14}, {"text": "CT", "start": 82, "end": 84, "id": 15}, {"text": "scan", "start": 85, "end": 89, "id": 16}, {"text": "for", "start": 90, "end": 93, "id": 17}, {"text": "patient", "start": 94, "end": 101, "id": 18}, {"text": "1", "start": 102, "end": 103, "id": 19}, {"text": ":", "start": 103, "end": 104, "id": 20}, {"text": "(", "start": 105, "end": 106, "id": 21}, {"text": "a", "start": 106, "end": 107, "id": 22}, {"text": ")", "start": 107, "end": 108, "id": 23}, {"text": "December", "start": 109, "end": 117, "id": 24}, {"text": "2017", "start": 118, "end": 122, "id": 25}, {"text": ";", "start": 122, "end": 123, "id": 26}, {"text": "(", "start": 124, "end": 125, "id": 27}, {"text": "b", "start": 125, "end": 126, "id": 28}, {"text": ")", "start": 126, "end": 127, "id": 29}, {"text": "July", "start": 128, "end": 132, "id": 30}, {"text": "2018", "start": 133, "end": 137, "id": 31}, {"text": ".", "start": 137, "end": 138, "id": 32}]}
{"pdf_hash": "5922d3fe62e13d3ddf688e2d3369adc63f91df46", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. Cross-sectional area (CSA) of multifidus muscles in a patient with right L5 radiculopathy. (A) shows axial planes at the mid-spinous process level of L4 vertebra (L4 MSP), the mid-spinous process level of L5 vertebra (L5 MSP), and the mid-sacral crest level of S1 vertebra (S1 MSC). (B) indicates total muscle CSA of multifidus muscles (TMCSA) at the S1 MSC. (C) indicates pure muscle CSA of multifidus muscles (PMCSA) at the S1 MSC.", "width": 1004, "height": 824, "subcaptions": {"a": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71], "b": [72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89], "c": [90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107]}, "subfigures": [{"id": "f99a95a5-f217-405a-b55f-e4e056b79fdf", "label": "a", "points": [[0.3, 4.2], [0.3, 821.1], [557, 821.1], [557, 4.2]], "color": "yellow"}, {"id": "556dcaf1-f8c3-4050-ae27-d3b718419d1f", "label": "b", "points": [[560.2, 4.2], [560.2, 403.9], [966.2, 403.9], [966.2, 4.2]], "color": "cyan"}, {"id": "012f9446-162b-476a-93a1-e774545c5542", "label": "c", "points": [[566.5, 411.9], [566.5, 817.9], [972.6, 817.9], [972.6, 411.9]], "color": "magenta"}], "tokens": [{"text": "Fig", 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{"pdf_hash": "721bb18129a4916a9f7ab423582b1a66a6683648", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Figure 2. The Spectrum of Fundus Findings among Different Families with Mutations in FAM161A (A\u2013I) Imaging of three pairs of siblings from families with the p.Thr452SerfsX3 mutation, showing different severity of funduscopic changes: bone-spicule-like pigmentation was observed to only a limited degree in most patients (A, C, D, F as compared to H, I), but many patients showed grayish spots extending from the arcades to the periphery. These correlated with spots of hypofluorescence on AF imaging (B, E, G). In addition, a ring of hyperfluoresence around the fovea could be observed in many cases (B, E, G). (J and K). Color fundus mosaic (J) and AF imaging of the macular area (K) in a patient with the R523X mutation. (L and M) OCT imaging shows marked thinning of the outer nuclear layer, with relative preservation under the fovea itself. Fine wrinkling of the retina can be seen in one of the scans (M), related to an epiretinal membrane.", "width": 1362, "height": 950, "subcaptions": {"b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128], "a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87], "c": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 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{"pdf_hash": "238ab8d80a838533d68e7296cc5e621a3c85a036", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "Figure 1. (A) Echocardiography (four-chamber view) depicting the mass (arrows) in the right atrium (RA). (B) Magnetic resonance imaging illustrating the rounded mass (arrows) attached to the right atrial free wall. LA, left atrium; LV, left ventricle; RA, right atrium; RV, right ventricle.", "width": 806, "height": 306, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "66dd1a07-a0b9-42f1-9392-a22f9f46b3dd", "label": "a", "points": [[7.1, 1.1], [7.1, 301.6], [378.8, 301.6], [378.8, 1.1]], "color": "yellow"}, {"id": "0a9ee75a-0a7d-4c71-99e9-4dbdd5a58bed", "label": "b", "points": [[394.1, 1.1], [394.1, 302.8], [800.3, 302.8], [800.3, 1.1]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Echocardiography", "start": 14, "end": 30, "id": 6}, {"text": "(", "start": 31, "end": 32, "id": 7}, {"text": "four", "start": 32, "end": 36, "id": 8}, {"text": "-", "start": 36, "end": 37, "id": 9}, {"text": "chamber", "start": 37, "end": 44, "id": 10}, {"text": "view", "start": 45, "end": 49, "id": 11}, {"text": ")", "start": 49, "end": 50, "id": 12}, {"text": "depicting", "start": 51, "end": 60, "id": 13}, {"text": "the", "start": 61, "end": 64, "id": 14}, {"text": "mass", "start": 65, "end": 69, "id": 15}, {"text": "(", "start": 70, "end": 71, "id": 16}, {"text": "arrows", "start": 71, "end": 77, "id": 17}, {"text": ")", "start": 77, "end": 78, "id": 18}, {"text": "in", "start": 79, "end": 81, "id": 19}, {"text": "the", "start": 82, "end": 85, "id": 20}, {"text": "right", "start": 86, "end": 91, "id": 21}, {"text": "atrium", "start": 92, "end": 98, "id": 22}, {"text": "(", "start": 99, "end": 100, "id": 23}, {"text": "RA", "start": 100, "end": 102, "id": 24}, {"text": ")", "start": 102, "end": 103, "id": 25}, {"text": ".", "start": 103, "end": 104, "id": 26}, {"text": "(", "start": 105, "end": 106, "id": 27}, {"text": "B", "start": 106, "end": 107, "id": 28}, {"text": ")", "start": 107, "end": 108, "id": 29}, {"text": "Magnetic", "start": 109, "end": 117, "id": 30}, {"text": "resonance", "start": 118, "end": 127, "id": 31}, {"text": "imaging", "start": 128, "end": 135, "id": 32}, {"text": "illustrating", "start": 136, "end": 148, "id": 33}, {"text": "the", "start": 149, "end": 152, "id": 34}, {"text": "rounded", "start": 153, "end": 160, "id": 35}, {"text": "mass", "start": 161, "end": 165, "id": 36}, {"text": "(", "start": 166, "end": 167, "id": 37}, {"text": "arrows", "start": 167, "end": 173, "id": 38}, {"text": ")", "start": 173, "end": 174, "id": 39}, {"text": "attached", "start": 175, "end": 183, "id": 40}, {"text": "to", "start": 184, "end": 186, "id": 41}, {"text": "the", "start": 187, "end": 190, "id": 42}, {"text": "right", "start": 191, "end": 196, "id": 43}, {"text": "atrial", "start": 197, "end": 203, "id": 44}, {"text": "free", "start": 204, "end": 208, "id": 45}, {"text": "wall", "start": 209, "end": 213, "id": 46}, {"text": ".", "start": 213, "end": 214, "id": 47}, {"text": "LA", "start": 215, "end": 217, "id": 48}, {"text": ",", "start": 217, "end": 218, "id": 49}, {"text": "left", "start": 219, "end": 223, "id": 50}, {"text": "atrium", "start": 224, "end": 230, "id": 51}, {"text": ";", "start": 230, "end": 231, "id": 52}, {"text": "LV", "start": 232, "end": 234, "id": 53}, {"text": ",", "start": 234, "end": 235, "id": 54}, {"text": "left", "start": 236, "end": 240, "id": 55}, {"text": "ventricle", "start": 241, "end": 250, "id": 56}, {"text": ";", "start": 250, "end": 251, "id": 57}, {"text": "RA", "start": 252, "end": 254, "id": 58}, {"text": ",", "start": 254, "end": 255, "id": 59}, {"text": "right", "start": 256, "end": 261, "id": 60}, {"text": "atrium", "start": 262, "end": 268, "id": 61}, {"text": ";", "start": 268, "end": 269, "id": 62}, {"text": "RV", "start": 270, "end": 272, "id": 63}, {"text": ",", "start": 272, "end": 273, "id": 64}, {"text": "right", "start": 274, "end": 279, "id": 65}, {"text": "ventricle", "start": 280, "end": 289, "id": 66}, {"text": ".", "start": 289, "end": 290, "id": 67}]}
{"pdf_hash": "cb61ad61fe235fe6bd8eda072958f98c633538b8", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig. 1. Areas of decreased blood flow measured using H 2 15 0 PET in an unmedicated patient during the experience of auditory and visual hallucinations (P b 0.01). Axial (A) and midsagittal (B) views showing decreased blood flow in right rostral prefrontal and ventromedial prefrontal cortices as well as in left dorsolateral prefrontal subcortical region. See [59] for methodological details and for areas of increased blood flow during hallucinations.", "width": 896, "height": 538, "subcaptions": {"a": [34, 35, 36, 37], "b": [40, 41, 42, 39]}, "subfigures": [{"id": "53f6d6bc-ada5-4f6e-b36c-36d3d50de303", "label": "a", "points": [[3.5, 32.1], [3.5, 510.5], [381.5, 510.5], [381.5, 32.1]], "color": "yellow"}, {"id": "903faee3-79ba-4202-899e-6252ba3118b2", "label": "b", "points": [[397.1, 33.5], [397.1, 504.9], [895.3, 504.9], [895.3, 33.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Areas", "start": 8, "end": 13, "id": 4}, {"text": "of", "start": 14, "end": 16, "id": 5}, {"text": "decreased", "start": 17, "end": 26, "id": 6}, {"text": "blood", "start": 27, "end": 32, "id": 7}, {"text": "flow", "start": 33, "end": 37, "id": 8}, {"text": "measured", "start": 38, "end": 46, "id": 9}, {"text": "using", "start": 47, "end": 52, "id": 10}, {"text": "H", "start": 53, "end": 54, "id": 11}, {"text": "2", "start": 55, "end": 56, "id": 12}, {"text": "15", "start": 57, "end": 59, "id": 13}, {"text": "0", "start": 60, "end": 61, "id": 14}, {"text": "PET", "start": 62, "end": 65, "id": 15}, {"text": "in", "start": 66, "end": 68, "id": 16}, {"text": "an", "start": 69, "end": 71, "id": 17}, {"text": "unmedicated", "start": 72, "end": 83, "id": 18}, {"text": "patient", "start": 84, "end": 91, "id": 19}, {"text": "during", "start": 92, "end": 98, "id": 20}, {"text": "the", "start": 99, "end": 102, "id": 21}, {"text": "experience", "start": 103, "end": 113, "id": 22}, {"text": "of", "start": 114, "end": 116, "id": 23}, {"text": "auditory", "start": 117, "end": 125, "id": 24}, {"text": "and", "start": 126, "end": 129, "id": 25}, {"text": "visual", "start": 130, "end": 136, "id": 26}, {"text": "hallucinations", "start": 137, "end": 151, "id": 27}, {"text": "(", "start": 152, "end": 153, "id": 28}, {"text": "P", "start": 153, "end": 154, "id": 29}, {"text": "b", "start": 155, "end": 156, "id": 30}, {"text": "0.01", "start": 157, "end": 161, "id": 31}, {"text": ")", "start": 161, "end": 162, "id": 32}, {"text": ".", "start": 162, "end": 163, "id": 33}, {"text": "Axial", "start": 164, "end": 169, "id": 34}, {"text": "(", "start": 170, "end": 171, "id": 35}, {"text": "A", "start": 171, "end": 172, "id": 36}, {"text": ")", "start": 172, "end": 173, "id": 37}, {"text": "and", "start": 174, "end": 177, "id": 38}, {"text": "midsagittal", "start": 178, "end": 189, "id": 39}, {"text": "(", "start": 190, "end": 191, "id": 40}, {"text": "B", "start": 191, "end": 192, "id": 41}, {"text": ")", "start": 192, "end": 193, "id": 42}, {"text": "views", "start": 194, "end": 199, "id": 43}, {"text": "showing", "start": 200, "end": 207, "id": 44}, {"text": "decreased", "start": 208, "end": 217, "id": 45}, {"text": "blood", "start": 218, "end": 223, "id": 46}, {"text": "flow", "start": 224, "end": 228, "id": 47}, {"text": "in", "start": 229, "end": 231, "id": 48}, {"text": "right", "start": 232, "end": 237, "id": 49}, {"text": "rostral", "start": 238, "end": 245, "id": 50}, {"text": "prefrontal", "start": 246, "end": 256, "id": 51}, {"text": "and", "start": 257, "end": 260, "id": 52}, {"text": "ventromedial", "start": 261, "end": 273, "id": 53}, {"text": "prefrontal", "start": 274, "end": 284, "id": 54}, {"text": "cortices", "start": 285, "end": 293, "id": 55}, {"text": "as", "start": 294, "end": 296, "id": 56}, {"text": "well", "start": 297, "end": 301, "id": 57}, {"text": "as", "start": 302, "end": 304, "id": 58}, {"text": "in", "start": 305, "end": 307, "id": 59}, {"text": "left", "start": 308, "end": 312, "id": 60}, {"text": "dorsolateral", "start": 313, "end": 325, "id": 61}, {"text": "prefrontal", "start": 326, "end": 336, "id": 62}, {"text": "subcortical", "start": 337, "end": 348, "id": 63}, {"text": "region", "start": 349, "end": 355, "id": 64}, {"text": ".", "start": 355, "end": 356, "id": 65}, {"text": "See", "start": 357, "end": 360, "id": 66}, {"text": "[", "start": 361, "end": 362, "id": 67}, {"text": "59", "start": 362, "end": 364, "id": 68}, {"text": "]", "start": 364, "end": 365, "id": 69}, {"text": "for", "start": 366, "end": 369, "id": 70}, {"text": "methodological", "start": 370, "end": 384, "id": 71}, {"text": "details", "start": 385, "end": 392, "id": 72}, {"text": "and", "start": 393, "end": 396, "id": 73}, {"text": "for", "start": 397, "end": 400, "id": 74}, {"text": "areas", "start": 401, "end": 406, "id": 75}, {"text": "of", "start": 407, "end": 409, "id": 76}, {"text": "increased", "start": 410, "end": 419, "id": 77}, {"text": "blood", "start": 420, "end": 425, "id": 78}, {"text": "flow", "start": 426, "end": 430, "id": 79}, {"text": "during", "start": 431, "end": 437, "id": 80}, {"text": "hallucinations", "start": 438, "end": 452, "id": 81}, {"text": ".", "start": 452, "end": 453, "id": 82}]}
{"pdf_hash": "2edaf01db436c97d3051e73af167d26492814433", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. A, The mass showed in T1-weighted coronary MRI. B, The mass showed in T1-weighted transverse MRI. C, The mass showed in T2-weighted coronary MRI. D, The mass showed in T2-weighted transverse MRI. CT = computed tomography, MRI = magnetic resonance imaging.", "width": 1340, "height": 298, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11], "b": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "c": [23, 24, 25, 26, 27, 28, 29, 30, 31], "d": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "c7ac51e5-b065-4ca9-acdb-2343e229b050", "label": "a", "points": [[40.6, 19.8], [40.6, 282.3], [336.9, 282.3], [336.9, 19.8]], "color": "yellow"}, {"id": "0a56c0f2-be53-4733-a1dd-1e489e1d632e", "label": "b", "points": [[347.5, 21.9], [347.5, 271.7], [677.8, 271.7], [677.8, 21.9]], "color": "cyan"}, {"id": "46b0b397-ecad-47b8-a20c-fe9984bc44ab", "label": "c", "points": [[694.7, 28.2], [694.7, 273.8], [984.7, 273.8], [984.7, 28.2]], "color": "magenta"}, {"id": "ed732f7f-dcee-46c3-9d56-0d7396d054d3", "label": "d", "points": [[1001.7, 21.9], [1001.7, 271.7], [1306.5, 271.7], [1306.5, 21.9]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "The", "start": 13, "end": 16, "id": 5}, {"text": "mass", "start": 17, "end": 21, "id": 6}, {"text": "showed", "start": 22, "end": 28, "id": 7}, {"text": "in", "start": 29, "end": 31, "id": 8}, {"text": "T1-weighted", "start": 32, "end": 43, "id": 9}, {"text": "coronary", "start": 44, "end": 52, "id": 10}, {"text": "MRI", "start": 53, "end": 56, "id": 11}, {"text": ".", "start": 56, "end": 57, "id": 12}, {"text": "B", "start": 58, "end": 59, "id": 13}, {"text": ",", "start": 59, "end": 60, "id": 14}, {"text": "The", "start": 61, "end": 64, "id": 15}, {"text": "mass", "start": 65, "end": 69, "id": 16}, {"text": "showed", "start": 70, "end": 76, "id": 17}, {"text": "in", "start": 77, "end": 79, "id": 18}, {"text": "T1-weighted", "start": 80, "end": 91, "id": 19}, {"text": "transverse", "start": 92, "end": 102, "id": 20}, {"text": "MRI", "start": 103, "end": 106, "id": 21}, {"text": ".", "start": 106, "end": 107, "id": 22}, {"text": "C", "start": 108, "end": 109, "id": 23}, {"text": ",", "start": 109, "end": 110, "id": 24}, {"text": "The", "start": 111, "end": 114, "id": 25}, {"text": "mass", "start": 115, "end": 119, "id": 26}, {"text": "showed", "start": 120, "end": 126, "id": 27}, {"text": "in", "start": 127, "end": 129, "id": 28}, {"text": "T2-weighted", "start": 130, "end": 141, "id": 29}, {"text": "coronary", "start": 142, "end": 150, "id": 30}, {"text": "MRI", "start": 151, "end": 154, "id": 31}, {"text": ".", "start": 154, "end": 155, "id": 32}, {"text": "D", "start": 156, "end": 157, "id": 33}, {"text": ",", "start": 157, "end": 158, "id": 34}, {"text": "The", "start": 159, "end": 162, "id": 35}, {"text": "mass", "start": 163, "end": 167, "id": 36}, {"text": "showed", "start": 168, "end": 174, "id": 37}, {"text": "in", "start": 175, "end": 177, "id": 38}, {"text": "T2-weighted", "start": 178, "end": 189, "id": 39}, {"text": "transverse", "start": 190, "end": 200, "id": 40}, {"text": "MRI", "start": 201, "end": 204, "id": 41}, {"text": ".", "start": 204, "end": 205, "id": 42}, {"text": "CT", "start": 206, "end": 208, "id": 43}, {"text": "=", "start": 209, "end": 210, "id": 44}, {"text": "computed", "start": 211, "end": 219, "id": 45}, {"text": "tomography", "start": 220, "end": 230, "id": 46}, {"text": ",", "start": 230, "end": 231, "id": 47}, {"text": "MRI", "start": 232, "end": 235, "id": 48}, {"text": "=", "start": 236, "end": 237, "id": 49}, {"text": "magnetic", "start": 238, "end": 246, "id": 50}, {"text": "resonance", "start": 247, "end": 256, "id": 51}, {"text": "imaging", "start": 257, "end": 264, "id": 52}, {"text": ".", "start": 264, "end": 265, "id": 53}]}
{"pdf_hash": "4caa328a6b1039ed16a8212744f328426af3c44b", "fig_key": "Figure4", "fig_uri": "7-Figure4-1.png", "text": "Fig. 4 a Sagittal atlas map and b photomicrographs of adjacent sections stained for myelin, d AChE and c immunoreacted for SMI-32, e CR, and f CB. Case Hb3. Scale bar (upper left panel): 2 mm", "width": 1004, "height": 970, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24], "c": [25, 26], "d": [27, 28, 29, 30]}, "subfigures": [{"id": "2ebebfc5-976a-43ae-874a-6e5d36e659ff", "label": "a", "points": [[3.2, 6.3], [3.2, 318.8], [493.3, 318.8], [493.3, 6.3]], "color": "yellow"}, {"id": "cb9822ec-f995-4b46-843a-f1b3a382e730", "label": "b", "points": [[511.6, 8.4], [511.6, 319], [1000, 319], [1000, 8.4]], "color": "tomato"}, {"id": "05a3ef0e-711c-4f08-9e3d-457c14ebeac0", "label": "c", "points": [[5.6, 328.6], [5.6, 645.7], [498.8, 645.7], [498.8, 328.6]], "color": "deepskyblue"}, {"id": "3a0af37b-7b37-4d97-a3e8-1ad0e282f399", "label": "d", "points": [[507.6, 328.3], [507.6, 647.1], [1000.8, 647.1], [1000.8, 328.3]], "color": "cyan"}, {"id": "21703f50-bf4c-4473-9e5d-b0264c79aa7f", "label": "e", "points": [[1.6, 661.4], [1.6, 964.3], [499.6, 964.3], [499.6, 661.4]], "color": "magenta"}, {"id": "ab9ac641-e636-41af-9c7e-de7ed0d33df8", "label": "f", "points": [[509.1, 659.8], [509.1, 969.1], [996.1, 969.1], [996.1, 659.8]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Sagittal", "start": 9, "end": 17, "id": 4}, {"text": "atlas", "start": 18, "end": 23, "id": 5}, {"text": "map", "start": 24, "end": 27, "id": 6}, {"text": "and", "start": 28, "end": 31, "id": 7}, {"text": "b", "start": 32, "end": 33, "id": 8}, {"text": "photomicrographs", "start": 34, "end": 50, "id": 9}, {"text": "of", "start": 51, "end": 53, "id": 10}, {"text": "adjacent", "start": 54, "end": 62, "id": 11}, {"text": "sections", "start": 63, "end": 71, "id": 12}, {"text": "stained", "start": 72, "end": 79, "id": 13}, {"text": "for", "start": 80, "end": 83, "id": 14}, {"text": "myelin", "start": 84, "end": 90, "id": 15}, {"text": ",", "start": 90, "end": 91, "id": 16}, {"text": "d", "start": 92, "end": 93, "id": 17}, {"text": "AChE", "start": 94, "end": 98, "id": 18}, {"text": "and", "start": 99, "end": 102, "id": 19}, {"text": "c", "start": 103, "end": 104, "id": 20}, {"text": "immunoreacted", "start": 105, "end": 118, "id": 21}, {"text": "for", "start": 119, "end": 122, "id": 22}, {"text": "SMI-32", "start": 123, "end": 129, "id": 23}, {"text": ",", "start": 129, "end": 130, "id": 24}, {"text": "e", "start": 131, "end": 132, "id": 25}, {"text": "CR", "start": 133, "end": 135, "id": 26}, {"text": ",", "start": 135, "end": 136, "id": 27}, {"text": "and", "start": 137, "end": 140, "id": 28}, {"text": "f", "start": 141, "end": 142, "id": 29}, {"text": "CB", "start": 143, "end": 145, "id": 30}, {"text": ".", "start": 145, "end": 146, "id": 31}, {"text": "Case", "start": 147, "end": 151, "id": 32}, {"text": "Hb3", "start": 152, "end": 155, "id": 33}, {"text": ".", "start": 155, "end": 156, "id": 34}, {"text": "Scale", "start": 157, "end": 162, "id": 35}, {"text": "bar", "start": 163, "end": 166, "id": 36}, {"text": "(", "start": 167, "end": 168, "id": 37}, {"text": "upper", "start": 168, "end": 173, "id": 38}, {"text": "left", "start": 174, "end": 178, "id": 39}, {"text": "panel", "start": 179, "end": 184, "id": 40}, {"text": ")", "start": 184, "end": 185, "id": 41}, {"text": ":", "start": 185, "end": 186, "id": 42}, {"text": "2", "start": 187, "end": 188, "id": 43}, {"text": "mm", "start": 189, "end": 191, "id": 44}]}
{"pdf_hash": "be25839b86c21ae7e2ece9e3e3535365c95c048e", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1. A\u2013D: This figure shows ultrasonography still frames of ovarian xenotransplants (arrowheads) and different antral follicle states (arrows). Due to the ultrasonographical findings (one antral follicle, 1.4 mm in diameter, A), we decided to attempt the first oocyte recovery trial six weeks after transplantation. The animal was administered 30 IU eCG s.c. to support oocyte maturation. It was anesthetized 36 h later and its abdominal cavity was opened again. The kidney was exteriorized and the antral follicle cavity was punctured using a 100 \u00b5l syringe. However, no oocyte was recovered from the aspirated fluid. Nine days later we found a new 1.3 mm sized antral follicle (B) in the same animal that grew 2.2 (C) and 3.3 (D) mm in size. 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{"pdf_hash": "cffca3bba58083f32075916a1d439ba63e43e46f", "fig_key": "Figure8", "fig_uri": "10-Figure8-1.png", "text": "Fig. 8. Images obtained in 76-year-old male with glioblastoma. A. T2-weighted MR image shows intra-axial mass with surrounding edema in right parietal lobe. B. DWI shows high signal intensity in corresponding lesion, and thus suggesting high tumor cellularity. C. Contrast-enhanced, axial, T1-weighted MR image shows necrotic, contrastenhancing mass in same lesion. D. Contrast-enhanced SWI shows additional information regarding microhemorrhage and tumor microvessels around tumor necrosis seen on contrast-enhanced, T1-weighted image. 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{"pdf_hash": "9c53d3569c141b2791b193e5dcc52fba8177710c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Sample neuronal cell rendered by maximum intensity projection of different portions of the original 3D fluorescence microscopy image stack. This example emphasizes the multiscale nature of the neuron segmentation problem as part of the digital reconstruction task: from the whole-neuron level (A), through the level of dendritic branches and bifurcations (B), to the level of individual spines (C). It also serves to illustrate the complexity of the problem: while this is a fairly high-quality data set, still several branches are poorly stained and show low contrast, causing visual ambiguities (A). In practical live-cell imaging experiments the noise level may be considerably higher. 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{"pdf_hash": "a0a09d7466c245ceed68af6fcf38f4214bb23280", "fig_key": "Figure6", "fig_uri": "7-Figure6-1.png", "text": "Figure 6. MRI nodal abnormalities in three patients with prostate cancer. The left panel shows conventional MRI and the middle panel showed MRI obtained 24 hs after the administration of lymphotropic superparamagnetic nanoparticles. The right panel shows corresponding histologic analysis (hematoxylin and eosin). A, a homogeneous decrease in signal intensity due to the accumulation of lymphotropic superparamagnetic nanoparticles in a normal lymph node in the left iliac region. B, conventional MRI shows high signal intensity in an unenlarged iliac lymph node completely replaced by tumor. The nodal signal intensity remains high with nanoparticles. C, conventional MRI shows high signal intensity in a retroperitoneal node with micrometastases. MRI with lymphotropic superparamagnetic nanoparticles demonstrates two hyperintense within the node, corresponding to 2-mm metastases. 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{"pdf_hash": "b88eefbb7bef731e88adebf96c7b71ed6e351c04", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Mammographic and ultrasound findings of a 35-year-old woman with ductal carcinomas in situ (DCIS). Screening mammography (A) demonstrated a focal asymmetry in the left upper breast (arrow) and computer-aided detection applied mammography (B) detected the lesion (asterisk, marked by computer-aided detection program) (arrow). The breast ultrasound (C) demonstrated a ductal change in the left upper breast (arrows); this was a pathologically proven DCIS.", "width": 1346, "height": 952, "subcaptions": {"a": [32, 33, 34, 35, 36, 37, 38, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66], "c": [67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84]}, "subfigures": [{"id": "ff067068-41ad-4afd-8a5a-c613907ff077", "label": "a", "points": [[2.5, -0.7], [2.5, 473.5], [742.5, 473.5], [742.5, -0.7]], "color": "yellow"}, {"id": "b1817694-8535-46b8-a8a5-968a17fc0362", "label": "b", "points": [[4.6, 482], [4.6, 945.5], [746.7, 945.5], [746.7, 482]], "color": "cyan"}, {"id": "36801a0f-af24-4561-a2f6-e1a2feb26cbf", "label": "c", "points": [[763.7, -0.7], [763.7, 624.4], [1342.1, 624.4], [1342.1, -0.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", 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{"pdf_hash": "8e98409f1f0448146145941873f69879789bfdca", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "Fig 2. \u2014 Dose distribution for intensity-modulated protons (A) or intensity-modulated photons (B) in a transverse plane (computed tomography slice) through the center of the tumor in a patient with a thoracic paraspinal sarcoma. The isodose contours are represented by different colors (corresponding values in CGE are displayed below the figure). Note the significant reduction in lung and cardiac dose with intensitymodulated protons. From Weber DC, Trofimov AV, DeLaney TF, et al. A treatment planning comparison of intensity modulated photon and proton therapy for paraspinal sarcomas. Int J Radiat Oncol Biol Phys. 2004;58:1596-1606. Reprinted with permission from Elsevier.", "width": 1350, "height": 560, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13], "b": [15, 16, 17, 18, 19, 20, 21]}, "subfigures": [{"id": "b13ca404-23db-4fcd-8019-f50aaa43334d", "label": "a", "points": [[8.1, 3.9], [8.1, 526.4], [669.2, 526.4], [669.2, 3.9]], "color": "yellow"}, {"id": "0dd1ad18-c7da-4487-95a0-4e9475e6d677", "label": "b", "points": [[679.8, 6], [679.8, 530.7], [1347.3, 530.7], [1347.3, 6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "\u2014", "start": 7, "end": 8, "id": 3}, {"text": "Dose", "start": 9, "end": 13, "id": 4}, {"text": "distribution", "start": 14, "end": 26, "id": 5}, {"text": "for", "start": 27, "end": 30, "id": 6}, {"text": "intensity", "start": 31, "end": 40, "id": 7}, {"text": "-", "start": 40, "end": 41, "id": 8}, {"text": "modulated", "start": 41, "end": 50, "id": 9}, {"text": 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{"pdf_hash": "206c4a115dcd330686f6c9c242301970557d5011", "fig_key": "Figure5", "fig_uri": "8-Figure5-1.png", "text": "Figure 5. The 5-HT 2A receptor is expressed in regions appropriate for mediating propagation of activity A, fluo-4-loaded dextran-injected motor neurones during [Ca 2+ ] i imaging experiment. B, horizontal 20 \u00b5m cryostat section demonstrating immunoreactivity for the 5-HT 2A receptor. Strong staining is observed in the midline commissural area (vertical line indicates midline), and in the marginal zone lateral to the midline. This animal was dextran-injected in the b1 branchial arch, and motor neurones can be seen in the V motor group (nV) in red. Strong receptor immunoreactivity is also observed in the sensory axons of the V th sensory ganglion (gV). Arrows at right of figure show the dorsal and ventral axes, and apply to part C as well. C, co-immunolabelling for serotonin reactivity (red) and 5-HT 2A receptor (green). Receptor immunoreactivity is strong in processes crossing the midline, in a few serotonin-immunolabelled neurones immediately lateral to the midline (arrowheads), and in the marginal zone extending laterally. 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{"pdf_hash": "e829e1638fc1de317f63df3677848b37023b5153", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. CT scan of the patient\u2019s liver showed lipiodol accumulation ((A) post-TACE day 14), and liver abscess formation (arrow) of S7 ((B) post-TACE day 87). CT = computed tomography, TACE = transarterial chemoembolization.", "width": 970, "height": 418, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "74e111bb-92da-4272-a182-1851863ff34b", "label": "a", "points": [[33.7, 21.5], [33.7, 384.6], [473.5, 384.6], [473.5, 21.5]], "color": "yellow"}, {"id": "7b02e4ec-4528-4ba5-988b-ef79d5d3450f", "label": "b", "points": [[493.4, 23], [493.4, 389.2], [930.2, 389.2], [930.2, 23]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "scan", "start": 13, "end": 17, "id": 4}, {"text": "of", "start": 18, "end": 20, "id": 5}, {"text": "the", "start": 21, "end": 24, "id": 6}, {"text": "patient", "start": 25, "end": 32, "id": 7}, {"text": "\u2019s", "start": 32, "end": 34, "id": 8}, {"text": "liver", "start": 35, "end": 40, "id": 9}, {"text": "showed", "start": 41, "end": 47, "id": 10}, {"text": "lipiodol", "start": 48, "end": 56, "id": 11}, {"text": "accumulation", "start": 57, "end": 69, "id": 12}, {"text": "(", "start": 70, "end": 71, "id": 13}, {"text": "(", "start": 71, "end": 72, "id": 14}, {"text": "A", "start": 72, "end": 73, "id": 15}, {"text": ")", "start": 73, "end": 74, "id": 16}, {"text": "post", "start": 75, "end": 79, "id": 17}, {"text": "-", "start": 79, "end": 80, "id": 18}, {"text": "TACE", "start": 80, "end": 84, "id": 19}, {"text": "day", "start": 85, "end": 88, "id": 20}, {"text": "14", "start": 89, "end": 91, "id": 21}, {"text": ")", "start": 91, "end": 92, "id": 22}, {"text": ",", "start": 92, "end": 93, "id": 23}, {"text": "and", "start": 94, "end": 97, "id": 24}, {"text": "liver", "start": 98, "end": 103, "id": 25}, {"text": "abscess", "start": 104, "end": 111, "id": 26}, {"text": "formation", "start": 112, "end": 121, "id": 27}, {"text": "(", "start": 122, "end": 123, "id": 28}, {"text": "arrow", "start": 123, "end": 128, "id": 29}, {"text": ")", "start": 128, "end": 129, "id": 30}, {"text": "of", "start": 130, "end": 132, "id": 31}, {"text": "S7", "start": 133, "end": 135, "id": 32}, {"text": "(", "start": 136, "end": 137, "id": 33}, {"text": "(", "start": 137, "end": 138, "id": 34}, {"text": "B", "start": 138, "end": 139, "id": 35}, {"text": ")", "start": 139, "end": 140, "id": 36}, {"text": "post", "start": 141, "end": 145, "id": 37}, {"text": "-", "start": 145, "end": 146, "id": 38}, {"text": "TACE", "start": 146, "end": 150, "id": 39}, {"text": "day", "start": 151, "end": 154, "id": 40}, {"text": "87", "start": 155, "end": 157, "id": 41}, {"text": ")", "start": 157, "end": 158, "id": 42}, {"text": ".", "start": 158, "end": 159, "id": 43}, {"text": "CT", "start": 160, "end": 162, "id": 44}, {"text": "=", "start": 163, "end": 164, "id": 45}, {"text": "computed", "start": 165, "end": 173, "id": 46}, {"text": "tomography", "start": 174, "end": 184, "id": 47}, {"text": ",", "start": 184, "end": 185, "id": 48}, {"text": "TACE", "start": 186, "end": 190, "id": 49}, {"text": "=", "start": 191, "end": 192, "id": 50}, {"text": "transarterial", "start": 193, "end": 206, "id": 51}, {"text": "chemoembolization", "start": 207, "end": 224, "id": 52}, {"text": ".", "start": 224, "end": 225, "id": 53}]}
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{"pdf_hash": "5b3a600e2d90779c613c7398698ca2177909123b", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1: Axial cross-sections were obtained by computed tomography in patients with normal and high ABI. The image in a 47-year-old patient with normal ABI showed no obvious calcification (arrow) in abdominal aorta A. However, abdominal aorta calcification was evident (arrow) in a 46-year-old patient with high ABI B. Scale bar=1cm.", "width": 668, "height": 1336, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "b": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "68f4d0ea-9369-4d81-9c40-dd4c7ac4ffaa", "label": "a", "points": [[3.3, 2.8], [3.3, 623.3], [661.8, 623.3], [661.8, 2.8]], "color": "yellow"}, {"id": "26bbf231-476a-49e5-b3a1-b18267f76edf", "label": "b", "points": [[4.4, 697.9], [4.4, 1330], [661.8, 1330], [661.8, 697.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Axial", "start": 10, "end": 15, "id": 3}, {"text": "cross", "start": 16, "end": 21, "id": 4}, {"text": "-", "start": 21, "end": 22, "id": 5}, {"text": "sections", "start": 22, "end": 30, "id": 6}, {"text": "were", "start": 31, "end": 35, "id": 7}, {"text": "obtained", "start": 36, "end": 44, "id": 8}, {"text": "by", "start": 45, "end": 47, "id": 9}, {"text": "computed", "start": 48, "end": 56, "id": 10}, {"text": "tomography", "start": 57, "end": 67, "id": 11}, {"text": "in", "start": 68, "end": 70, "id": 12}, {"text": "patients", "start": 71, "end": 79, "id": 13}, {"text": "with", "start": 80, "end": 84, "id": 14}, {"text": "normal", "start": 85, "end": 91, "id": 15}, {"text": "and", "start": 92, "end": 95, "id": 16}, {"text": "high", "start": 96, "end": 100, "id": 17}, {"text": "ABI", "start": 101, "end": 104, "id": 18}, {"text": ".", "start": 104, "end": 105, "id": 19}, {"text": "The", "start": 106, "end": 109, "id": 20}, {"text": "image", "start": 110, "end": 115, "id": 21}, {"text": "in", "start": 116, "end": 118, "id": 22}, {"text": "a", "start": 119, "end": 120, "id": 23}, {"text": "47-year", "start": 121, "end": 128, "id": 24}, {"text": "-", "start": 128, "end": 129, "id": 25}, {"text": "old", "start": 129, "end": 132, "id": 26}, {"text": "patient", "start": 133, "end": 140, "id": 27}, {"text": "with", "start": 141, "end": 145, "id": 28}, {"text": "normal", "start": 146, "end": 152, "id": 29}, {"text": "ABI", "start": 153, "end": 156, "id": 30}, {"text": "showed", "start": 157, "end": 163, "id": 31}, {"text": "no", "start": 164, "end": 166, "id": 32}, {"text": "obvious", "start": 167, "end": 174, "id": 33}, {"text": "calcification", "start": 175, "end": 188, "id": 34}, {"text": "(", "start": 189, "end": 190, "id": 35}, {"text": "arrow", "start": 190, "end": 195, "id": 36}, {"text": ")", "start": 195, "end": 196, "id": 37}, {"text": "in", "start": 197, "end": 199, "id": 38}, {"text": "abdominal", "start": 200, "end": 209, "id": 39}, {"text": "aorta", "start": 210, "end": 215, "id": 40}, {"text": "A.", "start": 216, "end": 218, "id": 41}, {"text": "However", "start": 219, "end": 226, "id": 42}, {"text": ",", "start": 226, "end": 227, "id": 43}, {"text": "abdominal", "start": 228, "end": 237, "id": 44}, {"text": "aorta", "start": 238, "end": 243, "id": 45}, {"text": "calcification", "start": 244, "end": 257, "id": 46}, {"text": "was", "start": 258, "end": 261, "id": 47}, {"text": "evident", "start": 262, "end": 269, "id": 48}, {"text": "(", "start": 270, "end": 271, "id": 49}, {"text": "arrow", "start": 271, "end": 276, "id": 50}, {"text": ")", "start": 276, "end": 277, "id": 51}, {"text": "in", "start": 278, "end": 280, "id": 52}, {"text": "a", "start": 281, "end": 282, "id": 53}, {"text": "46-year", "start": 283, "end": 290, "id": 54}, {"text": "-", "start": 290, "end": 291, "id": 55}, {"text": "old", "start": 291, "end": 294, "id": 56}, {"text": "patient", "start": 295, "end": 302, "id": 57}, {"text": "with", "start": 303, "end": 307, "id": 58}, {"text": "high", "start": 308, "end": 312, "id": 59}, {"text": "ABI", "start": 313, "end": 316, "id": 60}, {"text": "B.", "start": 317, "end": 319, "id": 61}, {"text": "Scale", "start": 320, "end": 325, "id": 62}, {"text": "bar=1", "start": 326, "end": 331, "id": 63}, {"text": "cm", "start": 331, "end": 333, "id": 64}, {"text": ".", "start": 333, "end": 334, "id": 65}]}
{"pdf_hash": "7005732a14dce4b817642b7ebdd646210cb03a05", "fig_key": "Figure5", "fig_uri": "7-Figure5-1.png", "text": "Fig. 5 The axial (A) and sagittal (B) micro-CT MIP images show the location of the micrograph (C). Whilst the endplate portion of radial annular-endplate tears usually occurred at the cartilaginous/ vertebral endplate junction, in two discs the right mediolateral portion of the endplate tear occurred at the annulus/endplate junction (disc 5-L12 is shown). In both discs, only fibres inclined in the direction of the applied axial rotation were ruptured, in this case those of the in-plane lamellae (I), but not the cross-sectioned lamellae (C). IV inferior vertebra, rg residual gel. 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{"pdf_hash": "c2747e3f6624641016c518fc803f8d4825de10ed", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. X-ray diffraction (XRD) patterns of nanograined (NG) and coarse-grained (CG) Ti-6Al-4V alloys (a). Optical micrograph (b) and SEM magnified images (c) for CG microstructure, TEM bright-field (d), and dark-field (e) micrograph for NG microstructure.", "width": 866, "height": 1366, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "b": [32, 33, 41, 42, 43, 29, 30, 31], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43], "d": [64, 45, 46, 47, 48, 49, 50, 51, 61, 62, 63], "e": [64, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "1b623925-43d8-439b-a7f1-9e5dbcc0aa7d", "label": "a", "points": [[73.2, -0.2], [73.2, 499.1], [736.7, 499.1], [736.7, -0.2]], "color": "yellow"}, {"id": "f5c61016-90b9-4d66-a535-cc3485fb7a29", "label": "b", "points": [[4.8, 510.7], [4.8, 926.6], [415.2, 926.6], [415.2, 510.7]], "color": "cyan"}, {"id": "b0d54ee2-9d7b-4db7-8f0b-f1218af2b1f4", "label": "c", "points": [[442.6, 510.7], [442.6, 926.6], [858.5, 926.6], [858.5, 510.7]], "color": "magenta"}, {"id": "a947b394-37ae-4175-80d2-63c54e1b7291", "label": "d", "points": [[4.8, 948.5], [4.8, 1361.6], [416.6, 1361.6], [416.6, 948.5]], "color": "springgreen"}, {"id": "067497a8-2e94-4b92-8438-eca64151db8a", "label": "e", "points": [[444, 951.2], [444, 1364.4], [853, 1364.4], [853, 951.2]], "color": "tomato"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "X", "start": 10, "end": 11, "id": 3}, {"text": "-", "start": 11, "end": 12, "id": 4}, {"text": "ray", "start": 12, "end": 15, "id": 5}, {"text": "diffraction", "start": 16, "end": 27, "id": 6}, {"text": "(", "start": 28, "end": 29, "id": 7}, {"text": "XRD", "start": 29, "end": 32, "id": 8}, {"text": ")", "start": 32, "end": 33, "id": 9}, {"text": "patterns", "start": 34, "end": 42, "id": 10}, {"text": "of", "start": 43, "end": 45, "id": 11}, {"text": "nanograined", "start": 46, "end": 57, "id": 12}, {"text": "(", "start": 58, "end": 59, "id": 13}, {"text": "NG", "start": 59, "end": 61, "id": 14}, {"text": ")", "start": 61, "end": 62, "id": 15}, {"text": "and", "start": 63, "end": 66, "id": 16}, {"text": "coarse", "start": 67, "end": 73, "id": 17}, {"text": "-", "start": 73, "end": 74, "id": 18}, {"text": "grained", "start": 74, "end": 81, "id": 19}, {"text": "(", "start": 82, "end": 83, "id": 20}, {"text": "CG", "start": 83, "end": 85, "id": 21}, {"text": ")", "start": 85, "end": 86, "id": 22}, {"text": "Ti-6Al-4V", "start": 87, "end": 96, "id": 23}, {"text": "alloys", "start": 97, "end": 103, "id": 24}, {"text": "(", "start": 104, "end": 105, "id": 25}, {"text": "a", "start": 105, "end": 106, "id": 26}, {"text": ")", "start": 106, "end": 107, "id": 27}, {"text": ".", "start": 107, "end": 108, "id": 28}, {"text": "Optical", "start": 109, "end": 116, "id": 29}, {"text": "micrograph", "start": 117, "end": 127, "id": 30}, {"text": "(", "start": 128, "end": 129, "id": 31}, {"text": "b", "start": 129, "end": 130, "id": 32}, {"text": ")", "start": 130, "end": 131, "id": 33}, {"text": "and", "start": 132, "end": 135, "id": 34}, {"text": "SEM", "start": 136, "end": 139, "id": 35}, {"text": "magnified", "start": 140, "end": 149, "id": 36}, {"text": "images", "start": 150, "end": 156, "id": 37}, {"text": "(", "start": 157, "end": 158, "id": 38}, {"text": "c", "start": 158, "end": 159, "id": 39}, {"text": ")", "start": 159, "end": 160, "id": 40}, {"text": "for", "start": 161, "end": 164, "id": 41}, {"text": "CG", "start": 165, "end": 167, "id": 42}, {"text": "microstructure", "start": 168, "end": 182, "id": 43}, {"text": ",", "start": 182, "end": 183, "id": 44}, {"text": "TEM", "start": 184, "end": 187, "id": 45}, {"text": "bright", "start": 188, "end": 194, "id": 46}, {"text": "-", "start": 194, "end": 195, "id": 47}, {"text": "field", "start": 195, "end": 200, "id": 48}, {"text": "(", "start": 201, "end": 202, "id": 49}, {"text": "d", "start": 202, "end": 203, "id": 50}, {"text": ")", "start": 203, "end": 204, "id": 51}, {"text": ",", "start": 204, "end": 205, "id": 52}, {"text": "and", "start": 206, "end": 209, "id": 53}, {"text": "dark", "start": 210, "end": 214, "id": 54}, {"text": "-", "start": 214, "end": 215, "id": 55}, {"text": "field", "start": 215, "end": 220, "id": 56}, {"text": "(", "start": 221, "end": 222, "id": 57}, {"text": "e", "start": 222, "end": 223, "id": 58}, {"text": ")", "start": 223, "end": 224, "id": 59}, {"text": "micrograph", "start": 225, "end": 235, "id": 60}, {"text": "for", "start": 236, "end": 239, "id": 61}, {"text": "NG", "start": 240, "end": 242, "id": 62}, {"text": "microstructure", "start": 243, "end": 257, "id": 63}, {"text": ".", "start": 257, "end": 258, "id": 64}]}
{"pdf_hash": "9d43abd4f06fc7809f5217fe7d32d8db0b0930e8", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4 A 58-year-old woman with hepatitis C infection who had been detected as having a right hepatic nodule on contrast-enhanced CT (a, arrow). PET was requested for further assessment, and revealed FDG avidity of the hepatic mass (b, arrow) as well as FDG avid deposits below the anterior abdominal wall (c, arrow head). 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{"pdf_hash": "a11377da3718034b45b11669f57d4d7fb9c81f5d", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "FIGURE 4. Cerenkov luminescence imaging of a notched COB type plaque sutured close to the optic nerve. (A) Plaque is misaligned relative to the optic nerve. (B) Plaque is centered around the optic nerve but not close to the nerve. (C) Plaque is adjacent to the optic nerve. (D) Plaque is tilted away from the sclera, leading to an irregular and diffuse demarcation of the Cerenkov emission. 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{"pdf_hash": "5098f98e99279b607ba2fbcc4f20d8bc00e87157", "fig_key": "Figure6", "fig_uri": "5-Figure6-1.png", "text": "Figure 6 Case of schwannoma. Endoscopy reveals a slightly elevated lesion in the posterior wall of the body. Endoscopic ultrasonography (EUS) detects a round, hypoechoic tumor originating from the fourth layer and elastography as a hard tumor. Histology shows spindle cells with S-100 positivity by EUS-guided fine-needle aspiration (FNA). HE, hematoxylin and eosin.", "width": 1306, "height": 818, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "c": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "e": [43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61], "d": [64, 65, 66, 67, 62, 63]}, "subfigures": [{"id": "d5f0534d-b49d-4255-b3fd-8a74a62843d2", "label": "a", "points": [[73.3, 36.8], [73.3, 457.7], [651, 457.7], [651, 36.8]], "color": "cyan"}, {"id": "564b1f16-55b0-4bc1-8bd6-41e6b2f4560c", "label": "b", "points": [[735.6, 34.7], [735.6, 455.6], [1300.9, 455.6], [1300.9, 34.7]], "color": "tomato"}, {"id": "7fa4e0ea-16a4-44a7-b8d4-ed979f8b38b8", "label": "c", "points": [[7.3, 494.8], [7.3, 812.5], [384.8, 812.5], [384.8, 494.8]], "color": "yellow"}, {"id": "dae215a1-a0eb-49ed-af57-37c23b4475ab", "label": "d", "points": [[428.2, 492.7], [428.2, 810.5], [849, 810.5], [849, 492.7]], "color": "magenta"}, {"id": "98d39321-8c6a-4bbb-a35a-05f3e987a366", "label": "e", "points": [[886.2, 496.9], [886.2, 810.5], [1298.8, 810.5], [1298.8, 496.9]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": "Case", "start": 9, "end": 13, "id": 2}, {"text": "of", "start": 14, "end": 16, "id": 3}, {"text": "schwannoma", "start": 17, "end": 27, "id": 4}, {"text": ".", "start": 27, "end": 28, "id": 5}, {"text": "Endoscopy", "start": 29, "end": 38, "id": 6}, {"text": "reveals", "start": 39, "end": 46, "id": 7}, {"text": "a", "start": 47, "end": 48, "id": 8}, {"text": "slightly", "start": 49, "end": 57, "id": 9}, {"text": "elevated", "start": 58, "end": 66, "id": 10}, {"text": "lesion", "start": 67, "end": 73, "id": 11}, {"text": "in", "start": 74, "end": 76, "id": 12}, {"text": "the", "start": 77, "end": 80, "id": 13}, {"text": "posterior", "start": 81, "end": 90, "id": 14}, {"text": "wall", "start": 91, "end": 95, "id": 15}, {"text": "of", "start": 96, "end": 98, "id": 16}, {"text": "the", "start": 99, "end": 102, "id": 17}, {"text": "body", "start": 103, "end": 107, "id": 18}, {"text": ".", "start": 107, "end": 108, "id": 19}, {"text": "Endoscopic", "start": 109, "end": 119, "id": 20}, {"text": "ultrasonography", "start": 120, "end": 135, "id": 21}, {"text": "(", "start": 136, "end": 137, "id": 22}, {"text": "EUS", "start": 137, "end": 140, "id": 23}, {"text": ")", "start": 140, "end": 141, "id": 24}, {"text": "detects", "start": 142, "end": 149, "id": 25}, {"text": "a", "start": 150, "end": 151, "id": 26}, {"text": "round", "start": 152, "end": 157, "id": 27}, {"text": ",", "start": 157, "end": 158, "id": 28}, {"text": "hypoechoic", "start": 159, "end": 169, "id": 29}, {"text": "tumor", "start": 170, "end": 175, "id": 30}, {"text": "originating", "start": 176, "end": 187, "id": 31}, {"text": "from", "start": 188, "end": 192, "id": 32}, {"text": "the", "start": 193, "end": 196, "id": 33}, {"text": "fourth", "start": 197, "end": 203, "id": 34}, {"text": "layer", "start": 204, "end": 209, "id": 35}, {"text": "and", "start": 210, "end": 213, "id": 36}, {"text": "elastography", "start": 214, "end": 226, "id": 37}, {"text": "as", "start": 227, "end": 229, "id": 38}, {"text": "a", "start": 230, "end": 231, "id": 39}, {"text": "hard", "start": 232, "end": 236, "id": 40}, {"text": "tumor", "start": 237, "end": 242, "id": 41}, {"text": ".", "start": 242, "end": 243, "id": 42}, {"text": "Histology", "start": 244, "end": 253, "id": 43}, {"text": "shows", "start": 254, "end": 259, "id": 44}, {"text": "spindle", "start": 260, "end": 267, "id": 45}, {"text": "cells", "start": 268, "end": 273, "id": 46}, {"text": "with", "start": 274, "end": 278, "id": 47}, {"text": "S-100", "start": 279, "end": 284, "id": 48}, {"text": "positivity", "start": 285, "end": 295, "id": 49}, {"text": "by", "start": 296, "end": 298, "id": 50}, {"text": "EUS", "start": 299, "end": 302, "id": 51}, {"text": "-", "start": 302, "end": 303, "id": 52}, {"text": "guided", "start": 303, "end": 309, "id": 53}, {"text": "fine", "start": 310, "end": 314, "id": 54}, {"text": "-", "start": 314, "end": 315, "id": 55}, {"text": "needle", "start": 315, "end": 321, "id": 56}, {"text": "aspiration", "start": 322, "end": 332, "id": 57}, {"text": "(", "start": 333, "end": 334, "id": 58}, {"text": "FNA", "start": 334, "end": 337, "id": 59}, {"text": ")", "start": 337, "end": 338, "id": 60}, {"text": ".", "start": 338, "end": 339, "id": 61}, {"text": "HE", "start": 340, "end": 342, "id": 62}, {"text": ",", "start": 342, "end": 343, "id": 63}, {"text": "hematoxylin", "start": 344, "end": 355, "id": 64}, {"text": "and", "start": 356, "end": 359, "id": 65}, {"text": "eosin", "start": 360, "end": 365, "id": 66}, {"text": ".", "start": 365, "end": 366, "id": 67}]}
{"pdf_hash": "499647e9e083f8d12c7d3ebef86c4be07d583e50", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Endoscopic findings of multiple inflammatory polyps. A and B: Caps of fibrinopurulent exudate from the sigmoid colon to the rectum interspersed with normal colonic mucosa; C and D: Magnifying endoscopy shows an area in the cap of amorphous fibrinopurulent exudate and tortuous and long branching crypts under the cap; E: Endoscopic ultrasonography showed significant thickening of the colonic mucosa layers.", "width": 1340, "height": 796, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "c": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "d": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55], "e": [64, 65, 66, 67, 68, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "49df5880-d8da-4fbe-9868-b5830f57338a", "label": "a", "points": [[3.3, 6], [3.3, 395.5], [445.7, 395.5], [445.7, 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{"pdf_hash": "78e09ee8147c132df3a52557cfecd5fa9e17285d", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Fig. 4. 71-year-old woman who fell from chair after spontaneous intracranial hemorrhage. A. Coronal STIR images show increased signal intensity along posterior subcutaneous area of both scapular regions (arrows). B. Autopsy photography of upper back reveals fresh soft tissue hemorrhage in corresponding areas (arrows).", "width": 1378, "height": 354, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36], "b": [37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54]}, "subfigures": [{"id": "bedabd8a-0ffc-4239-bc50-79996b1a806f", "label": "a", "points": [[9.9, 8.4], [9.9, 328.4], [702.2, 328.4], [702.2, 8.4]], "color": "yellow"}, {"id": "891dd45e-b9a0-48ca-b640-75c0e7f97c20", "label": "b", "points": [[723.9, 10.5], [723.9, 326.2], [1372.7, 326.2], [1372.7, 10.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "71-year", "start": 8, "end": 15, "id": 4}, {"text": "-", "start": 15, "end": 16, "id": 5}, {"text": "old", "start": 16, "end": 19, "id": 6}, {"text": "woman", "start": 20, "end": 25, "id": 7}, {"text": "who", "start": 26, "end": 29, "id": 8}, {"text": "fell", "start": 30, "end": 34, "id": 9}, {"text": "from", "start": 35, "end": 39, "id": 10}, {"text": "chair", "start": 40, "end": 45, "id": 11}, {"text": "after", "start": 46, "end": 51, "id": 12}, {"text": "spontaneous", "start": 52, "end": 63, "id": 13}, {"text": "intracranial", "start": 64, "end": 76, "id": 14}, {"text": "hemorrhage", "start": 77, "end": 87, "id": 15}, {"text": ".", "start": 87, "end": 88, "id": 16}, {"text": "A.", "start": 89, "end": 91, "id": 17}, {"text": "Coronal", "start": 92, "end": 99, "id": 18}, {"text": "STIR", "start": 100, "end": 104, "id": 19}, {"text": "images", "start": 105, "end": 111, "id": 20}, {"text": "show", "start": 112, "end": 116, "id": 21}, {"text": "increased", "start": 117, "end": 126, "id": 22}, {"text": "signal", "start": 127, "end": 133, "id": 23}, {"text": "intensity", "start": 134, "end": 143, "id": 24}, {"text": "along", "start": 144, "end": 149, "id": 25}, {"text": "posterior", "start": 150, "end": 159, "id": 26}, {"text": "subcutaneous", "start": 160, "end": 172, "id": 27}, {"text": "area", "start": 173, "end": 177, "id": 28}, {"text": "of", "start": 178, "end": 180, "id": 29}, {"text": "both", "start": 181, "end": 185, "id": 30}, {"text": "scapular", "start": 186, "end": 194, "id": 31}, {"text": "regions", "start": 195, "end": 202, "id": 32}, {"text": "(", "start": 203, "end": 204, "id": 33}, {"text": "arrows", "start": 204, "end": 210, "id": 34}, {"text": ")", "start": 210, "end": 211, "id": 35}, {"text": ".", "start": 211, "end": 212, "id": 36}, {"text": "B.", "start": 213, "end": 215, "id": 37}, {"text": "Autopsy", "start": 216, "end": 223, "id": 38}, {"text": "photography", "start": 224, "end": 235, "id": 39}, {"text": "of", "start": 236, "end": 238, "id": 40}, {"text": "upper", "start": 239, "end": 244, "id": 41}, {"text": "back", "start": 245, "end": 249, "id": 42}, {"text": "reveals", "start": 250, "end": 257, "id": 43}, {"text": "fresh", "start": 258, "end": 263, "id": 44}, {"text": "soft", "start": 264, "end": 268, "id": 45}, {"text": "tissue", "start": 269, "end": 275, "id": 46}, {"text": "hemorrhage", "start": 276, "end": 286, "id": 47}, {"text": "in", "start": 287, "end": 289, "id": 48}, {"text": "corresponding", "start": 290, "end": 303, "id": 49}, {"text": "areas", "start": 304, "end": 309, "id": 50}, {"text": "(", "start": 310, "end": 311, "id": 51}, {"text": "arrows", "start": 311, "end": 317, "id": 52}, {"text": ")", "start": 317, "end": 318, "id": 53}, {"text": ".", "start": 318, "end": 319, "id": 54}]}
{"pdf_hash": "0a79d0f2348f3d005c1a4cd24fedffa5a964fc07", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 Dye injection study following percutaneous abscess drainage and pigtail catheter insertion (a AP radiograph, b CT scan reconstruction, both following dye injection). The abscess cavity is seen communicating only with the L4\u2013L5 disc level", "width": 646, "height": 568, "subcaptions": {"a": [16, 17, 15], "b": [19, 20, 21, 22]}, "subfigures": [{"id": "a0dbf2fd-d4ba-4436-9f6d-acefd90005b2", "label": "a", "points": [[1.5, 3.1], [1.5, 566.4], [331.2, 566.4], [331.2, 3.1]], "color": "yellow"}, {"id": "076b688d-bfc3-44c2-b6b4-9ecd926ddc26", "label": "b", "points": [[344.4, 286.8], [344.4, 564.4], [640.4, 564.4], [640.4, 286.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Dye", "start": 7, "end": 10, "id": 3}, {"text": "injection", "start": 11, "end": 20, "id": 4}, {"text": "study", "start": 21, "end": 26, "id": 5}, {"text": "following", "start": 27, "end": 36, "id": 6}, {"text": "percutaneous", "start": 37, "end": 49, "id": 7}, {"text": "abscess", "start": 50, "end": 57, "id": 8}, {"text": "drainage", "start": 58, "end": 66, "id": 9}, {"text": "and", "start": 67, "end": 70, "id": 10}, {"text": "pigtail", "start": 71, "end": 78, "id": 11}, {"text": "catheter", "start": 79, "end": 87, "id": 12}, {"text": "insertion", "start": 88, "end": 97, "id": 13}, {"text": "(", "start": 98, "end": 99, "id": 14}, {"text": "a", "start": 99, "end": 100, "id": 15}, {"text": "AP", "start": 101, "end": 103, "id": 16}, {"text": "radiograph", "start": 104, "end": 114, "id": 17}, {"text": ",", "start": 114, "end": 115, "id": 18}, {"text": "b", "start": 116, "end": 117, "id": 19}, {"text": "CT", "start": 118, "end": 120, "id": 20}, {"text": "scan", "start": 121, "end": 125, "id": 21}, {"text": "reconstruction", "start": 126, "end": 140, "id": 22}, {"text": ",", "start": 140, "end": 141, "id": 23}, {"text": "both", "start": 142, "end": 146, "id": 24}, {"text": "following", "start": 147, "end": 156, "id": 25}, {"text": "dye", "start": 157, "end": 160, "id": 26}, {"text": "injection", "start": 161, "end": 170, "id": 27}, {"text": ")", "start": 170, "end": 171, "id": 28}, {"text": ".", "start": 171, "end": 172, "id": 29}, {"text": "The", "start": 173, "end": 176, "id": 30}, {"text": "abscess", "start": 177, "end": 184, "id": 31}, {"text": "cavity", "start": 185, "end": 191, "id": 32}, {"text": "is", "start": 192, "end": 194, "id": 33}, {"text": "seen", "start": 195, "end": 199, "id": 34}, {"text": "communicating", "start": 200, "end": 213, "id": 35}, {"text": "only", "start": 214, "end": 218, "id": 36}, {"text": "with", "start": 219, "end": 223, "id": 37}, {"text": "the", "start": 224, "end": 227, "id": 38}, {"text": "L4\u2013L5", "start": 228, "end": 233, "id": 39}, {"text": "disc", "start": 234, "end": 238, "id": 40}, {"text": "level", "start": 239, "end": 244, "id": 41}]}
{"pdf_hash": "48276b8ab3a40f7b5341c9a24e6ec0017f3d99e6", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. Endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN). (a) Schematic of EUSCPN; (b) Color flow EUS image from the lesser curvature of the stomach showing a longitudinal view of the aorta (Ao) and celiac artery (CA); (c) EUS image of EUS-CPN during needle puncture. A 22- gauge needle was advanced adjacent to the CA origin. Arrowheads indicate the needle tip. 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{"pdf_hash": "c6cf73ae38f248b07e419bea91cc38f8da08ab1d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 Pretreatment of the right eye of a patient with pathological myopia. Top left, fundus photograph shows characteristic of pathological myopia and signs of choroidal neovascularisation (CNV). Top right, optical coherence tomography (OCT) shows subretinal fluid (asterisk). The CNV complex also is identifiable in OCT scan (white arrow). Bottom left, early phase of angiogram shows a classic CNV membrane. 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{"pdf_hash": "be993dfcd9ab37dfa781a156dd02267ee9487a21", "fig_key": "Figure5", "fig_uri": "4-Figure5-1.png", "text": "Figure 5 (A) lupus nephritis class V. light micrograph of a glomerulus with diffuse membranous glomerulonephritis (h&e stained, 200\u00d7). (B) P53 nuclear immunostaining of apoptotic cells in class II of clN, score II/III (200\u00d7). (C) Ki-67 nuclear immunostaining of mesangial proliferative glomeruli in class II of clN, score II/III (200\u00d7). (D) Moderate to severe mononuclear tubulointerstitial nephritis (h&e stained, 200\u00d7). 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{"pdf_hash": "82f96f69db958fb10e406350304ce97d3e6a96bc", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 A 36-year-old patient with aggressive non-Hodgkin s lymphoma who initially presented with a huge left axillary mass and partial response at completion of first-line chemotherapy. At re-staging 10 months later (a c), PET/CT with FDG demonstrates, in addition to local residual disease over the left axillary region, at least four occult hepatic lesions (fused-CT images not shown). Only one of the lesions (arrow) can be retrospectively identified on the contrast-enhanced abdominal CT performed 9 days earlier (d). The patient s condition deteriorated rapidly after the PET/CT exam.", "width": 782, "height": 814, "subcaptions": {"a": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79], "c": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79], "d": [80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106]}, "subfigures": [{"id": "6542d45d-2ebe-40ed-b1df-0b2f787bf7c3", "label": "a", "points": [[42.4, 20.8], [42.4, 810.2], [349.9, 810.2], [349.9, 20.8]], "color": "yellow"}, {"id": 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{"pdf_hash": "842bb144988fbea844001e7701ad3fbfb2d5478e", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: A. Venogram, performed with contrast injection in the left basilic vein, demonstrating a suboccluded left subclavian vein (red arrow) and the presence of a collateral vein (white arrows) draining into the right subclavian vein. B. Chest radiograph (anteroposterior view) obtained the day after the procedure. The coronary sinus pacing lead (green arrows) passes from the left subclavian vein to its final position via a collateral vein and the right subclavian vein. 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{"pdf_hash": "96f871aa52e395a66b0efbefd9ec681485517336", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1 HRCT images of the lower chest in a 16 year-old boy (Case 2) at presentation (A), and 8 weeks later after a 6-week course of erythromycin 250mg twice daily. The bilateral bronchiectasis and prominent centri-lobular nodules with a tree-in-bud pattern shows marked improvement on the follow-up scan.", "width": 1168, "height": 536, "subcaptions": {"a": [19, 20, 21, 22, 23], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66]}, "subfigures": [{"id": "55170e02-e0ad-470f-9cbd-9afcba0d0fe0", "label": "a", "points": [[6.5, -0.3], [6.5, 481.3], [582.2, 481.3], [582.2, -0.3]], "color": "yellow"}, {"id": "1fc164f7-9562-4b83-99d9-add8f10ede72", "label": "b", "points": [[617.2, 1.5], [617.2, 473.9], [1161.5, 473.9], [1161.5, 1.5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "HRCT", "start": 9, "end": 13, "id": 2}, {"text": "images", "start": 14, "end": 20, "id": 3}, {"text": "of", "start": 21, "end": 23, "id": 4}, {"text": "the", "start": 24, "end": 27, "id": 5}, {"text": "lower", "start": 28, "end": 33, "id": 6}, {"text": "chest", "start": 34, "end": 39, "id": 7}, {"text": "in", "start": 40, "end": 42, "id": 8}, {"text": "a", "start": 43, "end": 44, "id": 9}, {"text": "16", "start": 45, "end": 47, "id": 10}, {"text": "year", "start": 48, "end": 52, "id": 11}, {"text": "-", "start": 52, "end": 53, "id": 12}, {"text": "old", "start": 53, "end": 56, "id": 13}, {"text": "boy", "start": 57, "end": 60, "id": 14}, {"text": "(", "start": 61, "end": 62, "id": 15}, {"text": "Case", "start": 62, "end": 66, "id": 16}, {"text": "2", "start": 67, "end": 68, "id": 17}, {"text": ")", "start": 68, "end": 69, "id": 18}, {"text": "at", "start": 70, "end": 72, "id": 19}, {"text": "presentation", "start": 73, "end": 85, "id": 20}, {"text": "(", "start": 86, "end": 87, "id": 21}, {"text": "A", "start": 87, "end": 88, "id": 22}, {"text": ")", "start": 88, "end": 89, "id": 23}, {"text": ",", "start": 89, "end": 90, "id": 24}, {"text": "and", "start": 91, "end": 94, "id": 25}, {"text": "8", "start": 95, "end": 96, "id": 26}, {"text": "weeks", "start": 97, "end": 102, "id": 27}, {"text": "later", "start": 103, "end": 108, "id": 28}, {"text": "after", "start": 109, "end": 114, "id": 29}, {"text": "a", "start": 115, "end": 116, "id": 30}, {"text": "6-week", "start": 117, "end": 123, "id": 31}, {"text": "course", "start": 124, "end": 130, "id": 32}, {"text": "of", "start": 131, "end": 133, "id": 33}, {"text": "erythromycin", "start": 134, "end": 146, "id": 34}, {"text": "250", "start": 147, "end": 150, "id": 35}, {"text": "mg", "start": 150, "end": 152, "id": 36}, {"text": "twice", "start": 153, "end": 158, "id": 37}, {"text": "daily", "start": 159, "end": 164, "id": 38}, {"text": ".", "start": 164, "end": 165, "id": 39}, {"text": "The", "start": 166, "end": 169, "id": 40}, {"text": "bilateral", "start": 170, "end": 179, "id": 41}, {"text": "bronchiectasis", "start": 180, "end": 194, "id": 42}, {"text": "and", "start": 195, "end": 198, "id": 43}, {"text": "prominent", "start": 199, "end": 208, "id": 44}, {"text": "centri", "start": 209, "end": 215, "id": 45}, {"text": "-", "start": 215, "end": 216, "id": 46}, {"text": "lobular", "start": 216, "end": 223, "id": 47}, {"text": "nodules", "start": 224, "end": 231, "id": 48}, {"text": "with", "start": 232, "end": 236, "id": 49}, {"text": "a", "start": 237, "end": 238, "id": 50}, {"text": "tree", "start": 239, "end": 243, "id": 51}, {"text": "-", "start": 243, "end": 244, "id": 52}, {"text": "in", "start": 244, "end": 246, "id": 53}, {"text": "-", "start": 246, "end": 247, "id": 54}, {"text": "bud", "start": 247, "end": 250, "id": 55}, {"text": "pattern", "start": 251, "end": 258, "id": 56}, {"text": "shows", "start": 259, "end": 264, "id": 57}, {"text": "marked", "start": 265, "end": 271, "id": 58}, {"text": "improvement", "start": 272, "end": 283, "id": 59}, {"text": "on", "start": 284, "end": 286, "id": 60}, {"text": "the", "start": 287, "end": 290, "id": 61}, {"text": "follow", "start": 291, "end": 297, "id": 62}, {"text": "-", "start": 297, "end": 298, "id": 63}, {"text": "up", "start": 298, "end": 300, "id": 64}, {"text": "scan", "start": 301, "end": 305, "id": 65}, {"text": ".", "start": 305, "end": 306, "id": 66}]}
{"pdf_hash": "da73d03cda1d8a82b5535bbe7cdb523e6bda0401", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. A representative axial slice from the input images used for detecting WMHs at run time (left) and ground-truth data used for training the WMH detection method and validating the results (right)", "width": 962, "height": 200, "subcaptions": {"a": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40]}, "subfigures": [{"id": "4fdea765-7d6f-4523-a2b5-5d42ac563f82", "label": "a", "points": [[8, 37.8], [8, 165.4], [175.2, 165.4], [175.2, 37.8]], "color": "yellow"}, {"id": "eb8bbdbd-4766-4ad5-9d69-6162b4a2d59c", "label": "a", "points": [[193.4, 33.2], [193.4, 171.5], [366.7, 171.5], [366.7, 33.2]], "color": "cyan"}, {"id": "704eb2c5-f73f-448e-a876-2258d0a837c7", "label": "a", "points": [[381.9, 30.2], [381.9, 162.4], [558.2, 162.4], [558.2, 30.2]], "color": "magenta"}, {"id": "afd784a8-10bf-4a2f-b00f-26fd34250a27", "label": "b", "points": [[603.8, 21.1], [603.8, 162.4], [777, 162.4], [777, 21.1]], "color": "springgreen"}, {"id": "cc10b8f6-fb94-4501-8c63-5356d8ff48c0", "label": "b", "points": [[790.7, 25.6], [790.7, 160.9], [951.8, 160.9], [951.8, 25.6]], "color": "tomato"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": "representative", "start": 10, "end": 24, "id": 5}, {"text": "axial", "start": 25, "end": 30, "id": 6}, {"text": "slice", "start": 31, "end": 36, "id": 7}, {"text": "from", "start": 37, "end": 41, "id": 8}, {"text": "the", "start": 42, "end": 45, "id": 9}, {"text": "input", "start": 46, "end": 51, "id": 10}, {"text": "images", "start": 52, "end": 58, "id": 11}, {"text": "used", "start": 59, "end": 63, "id": 12}, {"text": "for", "start": 64, "end": 67, "id": 13}, {"text": "detecting", "start": 68, "end": 77, "id": 14}, {"text": "WMHs", "start": 78, "end": 82, "id": 15}, {"text": "at", "start": 83, "end": 85, "id": 16}, {"text": "run", "start": 86, "end": 89, "id": 17}, {"text": "time", "start": 90, "end": 94, "id": 18}, {"text": "(", "start": 95, "end": 96, "id": 19}, {"text": "left", "start": 96, "end": 100, "id": 20}, {"text": ")", "start": 100, "end": 101, "id": 21}, {"text": "and", "start": 102, "end": 105, "id": 22}, {"text": "ground", "start": 106, "end": 112, "id": 23}, {"text": "-", "start": 112, "end": 113, "id": 24}, {"text": "truth", "start": 113, "end": 118, "id": 25}, {"text": "data", "start": 119, "end": 123, "id": 26}, {"text": "used", "start": 124, "end": 128, "id": 27}, {"text": "for", "start": 129, "end": 132, "id": 28}, {"text": "training", "start": 133, "end": 141, "id": 29}, {"text": "the", "start": 142, "end": 145, "id": 30}, {"text": "WMH", "start": 146, "end": 149, "id": 31}, {"text": "detection", "start": 150, "end": 159, "id": 32}, {"text": "method", "start": 160, "end": 166, "id": 33}, {"text": "and", "start": 167, "end": 170, "id": 34}, {"text": "validating", "start": 171, "end": 181, "id": 35}, {"text": "the", "start": 182, "end": 185, "id": 36}, {"text": "results", "start": 186, "end": 193, "id": 37}, {"text": "(", "start": 194, "end": 195, "id": 38}, {"text": "right", "start": 195, "end": 200, "id": 39}, {"text": ")", "start": 200, "end": 201, "id": 40}]}
{"pdf_hash": "549b5fbe1b8f008edb404c72c087d9b7125014d0", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "FIGURE 3. Using methods from Rucker et al., 90 (a) preoperative liver model and registered swabbed point cloud acquired from intraoperative liver surface are shown with ultrasound image of segment III portal pedicle in (b), and (c) showing manual segmentation of structure. In (d) we see the planned model cloud with ultrasound slice (white arrow) showing alignment of pedicle based on rigid registration, and (e) is the close-up. Notice how inferior vessel region does not align with corresponding vascular structure. In (f), a deformation correction driven by the closest point mismatch in data shown in (a) has been performed, and (g) shows the new location of the structure as well as modified shapes to vasculature. It should be noted that in this example ultrasound data was used for validation only, i.e., no localized ultrasound structures were used within the alignment algorithm, only data shown in (a) was used. We should further note that the alignment error of this feature after rigid registration was estimated at 5.5 6 2.6 mm (10.9 mm maximum error). The error was reduced to 2.4 6 1.5 mm (5.4 mm maximum error) after modelbased deformation correction.", "width": 1274, "height": 752, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 47, 48, 49, 50, 51, 52, 31], "c": [32, 33, 34, 35, 36, 37, 38, 44, 45, 46, 47, 48, 49, 50, 51, 52, 31], "d": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77], "e": [80, 81, 82, 83, 84, 85, 86, 87, 88], "f": [102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125], "g": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145]}, "subfigures": [{"id": "3e9addf4-1582-41e3-9085-4e9f5e56c055", "label": "a", "points": [[9.1, 3.7], [9.1, 235.1], [325.1, 235.1], [325.1, 3.7]], "color": "yellow"}, {"id": "f9ba53d5-c23c-4b9d-aea4-0179f65a42f7", "label": "b", "points": [[5.1, 257.3], 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{"pdf_hash": "e88a091c8f010b854623af9e525d88175c9bb244", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Immunohistochemical localization of aFGF immunoreactivity in cerebral cortex and hippocampus. A shows a low-power photomicrograph of a coronal section spanning all of cerebral cortex and most of hippocampus. Few aFGF-positive neurons are observed in these areas. The cell identified by an arrow in A is shown at larger magnification in B. The irregular multipolar morphology of this cell is representative for the morphology of most aFGF-positive cortical and hippocampal neurons. Fibers containing aFGF immunoreactivity in cingulate cortex are shown in C. The density of labeled fibers appears to be too high for fibers that would originate solely from the few aFGF-positive neurons within cortex. Scale bars: A, 120 pm; B, 15 pm; C, 8 pm.", "width": 1352, "height": 1022, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "b": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "c": [83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93]}, "subfigures": [{"id": "4b7a4875-cac6-4592-becd-8b3a96ae0d4c", "label": "a", "points": [[32, 4.3], [32, 1008.1], [448.5, 1008.1], [448.5, 4.3]], "color": "yellow"}, {"id": "256003d6-7830-45cf-b8be-584ba0e969c6", "label": "b", "points": [[478.4, 1006], [478.4, 0], [905.6, 0], [905.6, 1006]], "color": "cyan"}, {"id": "b66c97f5-feb8-4925-a7e7-6edd7091f8a7", "label": "c", "points": [[931.3, 4.3], [931.3, 1008.1], [1341.4, 1008.1], [1341.4, 4.3]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": ".", 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{"pdf_hash": "a5c3dca3341102c95a5f165fd312dc50a552acaa", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A. Axial contrast-enhanced CT scan of the lower leg of a patient with plasma cell leukemia and anterior tibial compartment pyomyositis (patient 4) demonstrates edema and swelling in the anterior compartment with an associated rim-enhancing intramuscular abscess (arrow). B. 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{"pdf_hash": "c67ac8313ee73163c46a957eb38f94d6221c6928", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. A, Macular grid 5 (MG5) scan pattern (768 A-scans spiral from center outward; grid spacing, 0.14 mm in central 3 mm and 0.29 mm between 3 and 5 mm). B, Optical coherence tomography (OCT) image of MG5. C, Fast Macular Thickness Map scan pattern (6 radial line scans). 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{"pdf_hash": "b04c59696eb53eddaa65223264d19e6c11030447", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Morphometric analysis of the ribosome population in the G1 and G2 phases. (A) Example of a higher magnification view of a G1 cell with a mounted triple-lattice grid for counting the density of ribosomes. (B) An expanded view shows how the grid was mounted on a region proximal to the nuclear envelope. (C) An enlarged view shows the exact co-localization of the ribosome particle on the center white dot of the grid that represents one positive score. 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{"pdf_hash": "0f28fa06b6500e947bc1bcae61b7f9a516f80557", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1 Different ALK staining expression at IHC with clone 5A4 (A) and Ventana D5F3 CD assay (B). Insert in image (A) shows the ALK positivity in signet ring tumor cells with a thin rim of brownish-stained cytoplasm dislocated under the nuclear membrane. FISH analysis showing tumor cells with normal ALK set-up with one normal fusion signal and one single red/orange signal (C); ALK positivity by gene deletion with single 3' orange rearranged signals (deleted green signal) (D, arrowheads) and ALK positivity by inversion with \u201cbroken apart\u201d signals, 2 or more signal diameters apart (E, arrows). 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{"pdf_hash": "74a300a9f7a184359e05b7fadbc20b0a6b07c80f", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. X-ray crystal structure of the PPAR\u2425\u035eRXR\u2423 LBDs. (A) The PPAR\u2425 protein is displayed as a yellow worm and the RXR\u2423 protein as a dark blue worm with the LxxLL peptides in purple. The agonist ligands GW409544 and 9-cis-retinoic acid are displayed in space-filling representations colored by atom type. (B) A 2F o \u03ea Fc omit map showing the electron density (1) of the ligand and the surrounding residues. The amino acids Phe-282, Tyr-323, and Tyr-473 are indicated. 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{"pdf_hash": "ea4f492e838b17260e8c4b087b3e212d6c49d7b3", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2. Subcellular localization of InsP3R isoforms in HepG2 cells. Type II and III InsP 3Rs were localized by confocal immunofluorescence. Cells were doublelabeled with isoform-specific InsP 3R antibodies (green) or with added propidium iodide (red) to identify the nucleus. (A) Type II InsP 3R labeling. (B) Propidium iodide. (C) Merged images demonstrate that type II InsP 3R is in both cytosol and nucleus. Notice the reticular pattern of nuclear staining. (D) Type III InsP 3R labeling. (E) Propidium iodide. (F) Merged images demonstrate that type III InsP 3R is in the cytosol but not in the nucleus of HepG2 cells. Labeling with secondary but not primary antibody plus propidium iodide reveals no nonspecific staining (not shown).", "width": 684, "height": 476, "subcaptions": {"a": [51, 52, 53, 54, 55, 56, 57, 58, 59], "b": [60, 61, 62, 63, 64, 65], "c": [66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91], "d": [92, 93, 94, 95, 96, 97, 98, 99, 100], "e": [101, 102, 103, 104, 105, 106], "f": [107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130]}, "subfigures": [{"id": "51bd755a-3e03-4d76-8c83-a9f4b8ac8d3d", "label": "a", "points": [[7.1, 2], [7.1, 219.2], [222.1, 219.2], [222.1, 2]], "color": "yellow"}, {"id": "b7eeb759-f466-42cc-913d-a8421f9e8ecf", "label": "b", "points": [[235.1, 3.1], [235.1, 219.2], [452.2, 219.2], [452.2, 3.1]], "color": "cyan"}, {"id": "fee0bbef-508b-46df-9d9f-1c29d44cb5b5", "label": "c", "points": [[463, -0.2], [463, 215.9], [675.9, 215.9], [675.9, -0.2]], 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{"pdf_hash": "b06f940a1d8d32ff5fbfcc8258e8ea7fa940ca02", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. 61-year-old woman with well differentiated retroperitoneal liposarcoma. A. Axial contrast-enhanced CT image at time of diagnosis demonstrates large predominantly fat containing mass in left retroperitoneum (arrows). Presence of heterogeneous non-lipomatous component differentiates it from simple lipoma. B, C. Axial T1-out-of-phase and post-gadolinium fatsuppressed T1-weighted images demonstrate mass to have areas of signal drop on out-of-phase imaging with no significant enhancement (arrows). Patient underwent surgery and histopathology showed well-differentiated liposarcoma.", "width": 1380, "height": 390, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50], "b": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89], "c": [51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89]}, "subfigures": [{"id": "b03530c9-4cb5-4aa1-93ef-12d588125493", "label": "a", "points": [[0, 2.2], [0, 342.3], [449.1, 342.3], [449.1, 2.2]], "color": "yellow"}, {"id": "6c2d52e3-52b4-44ac-90e5-7fb8e63dd3fa", "label": "b", "points": [[470.9, 344.5], [470.9, 2.2], [915.6, 2.2], [915.6, 344.5]], "color": "cyan"}, {"id": "956d210e-cbf9-4030-8925-6a69fa127e5a", "label": "c", "points": 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{"pdf_hash": "9b3a13bc73a9972d79497bb3c8aa15cd230ff837", "fig_key": "Figure12", "fig_uri": "11-Figure12-1.png", "text": "Fig. 12. Morphological features of the manchette during rat spermatogenesis. (A,B) Electron microscopy. (A) This electron micrograph shows the absence of the manchette at the start of acrosome formation in rat spermatogenesis. N: nucleus, PA: proacrosome (B) This electron micrograph shows the presence of the manchette (arrows) during nuclear shaping in rat spermatogenesis. N: nucleus (C,D) Immunofluorescent staining. These immunofluorescent light micrographs show the localization of tubulin (green staining) and KIFC1 (red staining) in rat spermatids. 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{"pdf_hash": "6733b9471d7ecac6ec17eca4f0d50788e8de4ecb", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Case 1. (A) Recurrent choroidal hemangioma with submacular fluid, previously treated by photocoagulation, before intravitreal bevacizumab. Ultrasonography reveals a tumor thickness of 1.6 mm. Optical coherence tomography (OCT) demonstrates the presence of submacular fluid. (B) Two months after intravitreal bevacizumab. The hemangioma thickness is reduced on ultrasonography and the subretinal fluid around the tumor is absorbed on OCT.", "width": 646, "height": 658, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75]}, "subfigures": [{"id": "f0c5c3f2-25c7-476c-90c4-cb8e5a9f0334", "label": "a", "points": [[0, 3.1], [0, 628.7], [319.4, 628.7], [319.4, 3.1]], "color": "yellow"}, {"id": "b6c0bada-e3e3-4b15-b4b9-15d582194699", "label": "b", "points": [[323.5, 632.7], [323.5, 4.1], [644, 4.1], [644, 632.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Case", "start": 8, "end": 12, "id": 4}, {"text": "1", "start": 13, "end": 14, "id": 5}, {"text": ".", "start": 14, "end": 15, "id": 6}, {"text": "(", "start": 16, "end": 17, "id": 7}, {"text": "A", "start": 17, "end": 18, "id": 8}, {"text": ")", "start": 18, "end": 19, "id": 9}, {"text": "Recurrent", "start": 20, "end": 29, "id": 10}, {"text": "choroidal", "start": 30, "end": 39, "id": 11}, {"text": "hemangioma", "start": 40, "end": 50, "id": 12}, {"text": "with", "start": 51, "end": 55, "id": 13}, {"text": "submacular", "start": 56, "end": 66, "id": 14}, {"text": "fluid", "start": 67, "end": 72, "id": 15}, {"text": ",", "start": 72, "end": 73, "id": 16}, {"text": "previously", "start": 74, "end": 84, "id": 17}, {"text": "treated", "start": 85, "end": 92, "id": 18}, {"text": "by", "start": 93, "end": 95, "id": 19}, {"text": "photocoagulation", "start": 96, "end": 112, "id": 20}, {"text": ",", "start": 112, "end": 113, "id": 21}, {"text": "before", "start": 114, "end": 120, "id": 22}, {"text": "intravitreal", "start": 121, "end": 133, "id": 23}, {"text": "bevacizumab", "start": 134, "end": 145, "id": 24}, {"text": ".", "start": 145, "end": 146, "id": 25}, {"text": "Ultrasonography", "start": 147, "end": 162, "id": 26}, {"text": "reveals", "start": 163, "end": 170, "id": 27}, {"text": "a", "start": 171, "end": 172, "id": 28}, {"text": "tumor", "start": 173, "end": 178, "id": 29}, {"text": "thickness", "start": 179, "end": 188, "id": 30}, {"text": "of", "start": 189, "end": 191, "id": 31}, {"text": "1.6", "start": 192, "end": 195, "id": 32}, {"text": "mm", "start": 196, "end": 198, "id": 33}, {"text": ".", "start": 198, "end": 199, "id": 34}, {"text": "Optical", "start": 200, "end": 207, "id": 35}, {"text": "coherence", "start": 208, "end": 217, "id": 36}, {"text": "tomography", "start": 218, "end": 228, "id": 37}, {"text": "(", "start": 229, "end": 230, "id": 38}, {"text": "OCT", "start": 230, "end": 233, "id": 39}, {"text": ")", "start": 233, "end": 234, "id": 40}, {"text": "demonstrates", "start": 235, "end": 247, "id": 41}, {"text": "the", "start": 248, "end": 251, "id": 42}, {"text": "presence", "start": 252, "end": 260, "id": 43}, {"text": "of", "start": 261, "end": 263, "id": 44}, {"text": "submacular", "start": 264, "end": 274, "id": 45}, {"text": "fluid", "start": 275, "end": 280, "id": 46}, {"text": ".", "start": 280, "end": 281, "id": 47}, {"text": "(", "start": 282, "end": 283, "id": 48}, {"text": "B", "start": 283, "end": 284, "id": 49}, {"text": ")", "start": 284, "end": 285, "id": 50}, {"text": "Two", "start": 286, "end": 289, "id": 51}, {"text": "months", "start": 290, "end": 296, "id": 52}, {"text": "after", "start": 297, "end": 302, "id": 53}, {"text": "intravitreal", "start": 303, "end": 315, "id": 54}, {"text": "bevacizumab", "start": 316, "end": 327, "id": 55}, {"text": ".", "start": 327, "end": 328, "id": 56}, {"text": "The", "start": 329, "end": 332, "id": 57}, {"text": "hemangioma", "start": 333, "end": 343, "id": 58}, {"text": "thickness", "start": 344, "end": 353, "id": 59}, {"text": "is", "start": 354, "end": 356, "id": 60}, {"text": "reduced", "start": 357, "end": 364, "id": 61}, {"text": "on", "start": 365, "end": 367, "id": 62}, {"text": "ultrasonography", "start": 368, "end": 383, "id": 63}, {"text": "and", "start": 384, "end": 387, "id": 64}, {"text": "the", "start": 388, "end": 391, "id": 65}, {"text": "subretinal", "start": 392, "end": 402, "id": 66}, {"text": "fluid", "start": 403, "end": 408, "id": 67}, {"text": "around", "start": 409, "end": 415, "id": 68}, {"text": "the", "start": 416, "end": 419, "id": 69}, {"text": "tumor", "start": 420, "end": 425, "id": 70}, {"text": "is", "start": 426, "end": 428, "id": 71}, {"text": "absorbed", "start": 429, "end": 437, "id": 72}, {"text": "on", "start": 438, "end": 440, "id": 73}, {"text": "OCT", "start": 441, "end": 444, "id": 74}, {"text": ".", "start": 444, "end": 445, "id": 75}]}
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{"pdf_hash": "2f49a93b0d5cdb7276f5f9e4e08eb76f0c8b86ed", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3. Defects associated with the Smad4 m4Mag allele. Hematoxylin and eosin-stained sagittal sections of E7.5 embryos are shown. (A) Wild-type gastrulating embryo showing newly formed mesoderm (arrow) and other well patterned structures. (B) Homozygous Smad4 tm1Cxd embryo. (C) Smad4 m4Mag \u035e Smad4 tm1Cxd embryo. (D) Homozygous Smad4 m4Mag embryo. (B-D) Compared with the wild-type E7.5 embryo (A), these mutant embryos are much smaller, with no sign of the initiation of gastrulation or the formation of mesoderm. Also note the disproportionally large cavity between the visceral and parietal endoderm (asterisks). (E) Steady-state level of SMAD4 protein in unmutagenized wild-type ES cells (lane 1) and three mutagenized sibling subclones (lane 2, wild-type for Smad4; lanes 3 and 4, heterozygous for Smad4 m4Mag ). 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{"pdf_hash": "8e7d535ec4ea6574bf9b0a36783c258e64bd72eb", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3: A 72\u2011year\u2011old female patient with a symptomatic carotid stenosis. Ultrasound examination showed: (a and b) Soft\u2011tissue mass, vascularized, with sonographic findings suggestive of thyroid tissue, located just above the geniohyoid muscle in the sublingual and suprahyoid space. 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{"pdf_hash": "a26874b34773a6e4e9427272f6ca9064d53a31ef", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Magnetic resonance imaging of the cervical spine. ''A'' is T2 sagittal acquisition; ''B'' is T1 post-gadolinium sagittal acquisition. White open arrow in ''A'' shows phlegmon or abscess within the prevertebral space between C1 and C6. White long arrow in ''A'' shows involvement of C6 vertebral body, likely representing osteomyelitis. White short arrow in ''A'' shows signal abnormality in the spinal cord, representing edema. 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{"pdf_hash": "b3e85bd94ce03734f3996cc21e15399179bf089f", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Foveal detachment from focal vitreoretinal adherence visualized with en face OCT. (a) En face longitudinal B-scan showing a dome-shaped non-reflective space under the fovea associated with loss of foveal contour and focal foveolar hyaloidal attachment (arrow). (b, c) Left, overlaid red-free coronal C-scan image; right, OCT C-scan. Consecutive anteroposterior C-scans. Angular size, 20 \u00c2 201. The sigmoid hyperreflective band and its relationships with the vascular arcades and the fovea are clearly detectable (arrow). (d) Left, red-free image; right, OCT C-scan. The hyporeflective circle represents the subretinal fluid. It is surrounded by the hyper-reflective ringshaped signal coming from the edges of the detachment. 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{"pdf_hash": "1bb9c9a337738122cfd07e6c848629bf3279abb3", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Grade I RPOH in a 69 years old male patient: AP (A) and axial (B) views of the left hip show partial joint space narrowing and clearly visible geodes in both the acetabulum and femoral head, creating and inhomogeneous aspect. The femoral head is not deformed or ascended.", "width": 1006, "height": 480, "subcaptions": {"a": [14, 15, 16, 17], "b": [19, 20, 21, 22]}, "subfigures": [{"id": "bbfa5fbb-cec8-4537-b8a9-84093dbe0315", "label": "a", "points": [[35.4, 20.4], [35.4, 459.1], [499.5, 459.1], [499.5, 20.4]], "color": "yellow"}, {"id": "6d3f4009-a9b8-4b07-9ba3-b9a1b12889b1", "label": "b", "points": [[512.2, 22], [512.2, 454.3], [965.1, 454.3], [965.1, 22]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Grade", "start": 10, "end": 15, "id": 3}, {"text": "I", "start": 16, "end": 17, "id": 4}, {"text": "RPOH", "start": 18, "end": 22, "id": 5}, {"text": "in", "start": 23, "end": 25, "id": 6}, {"text": "a", "start": 26, "end": 27, "id": 7}, {"text": "69", "start": 28, "end": 30, "id": 8}, {"text": "years", "start": 31, "end": 36, "id": 9}, {"text": "old", "start": 37, "end": 40, "id": 10}, {"text": "male", "start": 41, "end": 45, "id": 11}, {"text": "patient", "start": 46, "end": 53, "id": 12}, {"text": ":", "start": 53, "end": 54, "id": 13}, {"text": "AP", "start": 55, "end": 57, "id": 14}, {"text": "(", "start": 58, "end": 59, "id": 15}, {"text": "A", "start": 59, "end": 60, "id": 16}, {"text": ")", "start": 60, "end": 61, "id": 17}, {"text": "and", "start": 62, "end": 65, "id": 18}, {"text": "axial", "start": 66, "end": 71, "id": 19}, {"text": "(", "start": 72, "end": 73, "id": 20}, {"text": "B", "start": 73, "end": 74, "id": 21}, {"text": ")", "start": 74, "end": 75, "id": 22}, {"text": "views", "start": 76, "end": 81, "id": 23}, {"text": "of", "start": 82, "end": 84, "id": 24}, {"text": "the", "start": 85, "end": 88, "id": 25}, {"text": "left", "start": 89, "end": 93, "id": 26}, {"text": "hip", "start": 94, "end": 97, "id": 27}, {"text": "show", "start": 98, "end": 102, "id": 28}, {"text": "partial", "start": 103, "end": 110, "id": 29}, {"text": "joint", "start": 111, "end": 116, "id": 30}, {"text": "space", "start": 117, "end": 122, "id": 31}, {"text": "narrowing", "start": 123, "end": 132, "id": 32}, {"text": "and", "start": 133, "end": 136, "id": 33}, {"text": "clearly", "start": 137, "end": 144, "id": 34}, {"text": "visible", "start": 145, "end": 152, "id": 35}, {"text": "geodes", "start": 153, "end": 159, "id": 36}, {"text": "in", "start": 160, "end": 162, "id": 37}, {"text": "both", "start": 163, "end": 167, "id": 38}, {"text": "the", "start": 168, "end": 171, "id": 39}, {"text": "acetabulum", "start": 172, "end": 182, "id": 40}, {"text": "and", "start": 183, "end": 186, "id": 41}, {"text": "femoral", "start": 187, "end": 194, "id": 42}, {"text": "head", "start": 195, "end": 199, "id": 43}, {"text": ",", "start": 199, "end": 200, "id": 44}, {"text": "creating", "start": 201, "end": 209, "id": 45}, {"text": "and", "start": 210, "end": 213, "id": 46}, {"text": "inhomogeneous", "start": 214, "end": 227, "id": 47}, {"text": "aspect", "start": 228, "end": 234, "id": 48}, {"text": ".", "start": 234, "end": 235, "id": 49}, {"text": "The", "start": 236, "end": 239, "id": 50}, {"text": "femoral", "start": 240, "end": 247, "id": 51}, {"text": "head", "start": 248, "end": 252, "id": 52}, {"text": "is", "start": 253, "end": 255, "id": 53}, {"text": "not", "start": 256, "end": 259, "id": 54}, {"text": "deformed", "start": 260, "end": 268, "id": 55}, {"text": "or", "start": 269, "end": 271, "id": 56}, {"text": "ascended", "start": 272, "end": 280, "id": 57}, {"text": ".", "start": 280, "end": 281, "id": 58}]}
{"pdf_hash": "390b53b4991c60e6101ada79268621153486a19d", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Fig. 6. FeSEM of isolated nuclear envelopes from oocytes expressing high levels of lamin A after injection of 1.5 ng of plasmid DNA. (A,B) Lamin A filaments that are arranged in layered bundles are indicated by small arrows; they surround, but appear not to interact with, structures that are consistent with NPC baskets. In general, the distal basket ring is visible (large arrows), and sometimes basket filaments can be seen (arrowheads). Oocytes expressing lamin A were also analysed by TEM thin sections and compared with controls. 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{"pdf_hash": "eb14fc338dd866f60eccf382c7b9548a9867ee9c", "fig_key": "Figure3", "fig_uri": "8-Figure3-1.png", "text": "FIGURE 3 | Scanning electron microscopy (SEM) imaging of Devosia mutans 17-2-E-8 (A) and transmission electron microscopy (TEM) images (B,C) of isolate 17-2-E-8.", "width": 1370, "height": 534, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [32, 33, 34, 35, 36, 37, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [32, 33, 34, 35, 36, 37, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "2a27c05e-ff7f-4d71-9a80-508d1b04d9c5", "label": "a", "points": [[48.2, 73.3], [48.2, 523.5], [433.5, 523.5], [433.5, 73.3]], "color": "yellow"}, {"id": "e6c96b51-2d36-4853-8c86-5302cdc746cb", "label": "b", "points": [[466, 69], [466, 523.5], [872.9, 523.5], [872.9, 69]], "color": "cyan"}, {"id": "8c64f0df-9c2b-412e-84c5-58ecf26ce887", "label": "c", "points": [[931.3, 82], [931.3, 514.8], [1323, 514.8], [1323, 82]], "color": "magenta"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "|", "start": 9, "end": 10, "id": 2}, {"text": "Scanning", "start": 11, "end": 19, "id": 3}, {"text": "electron", "start": 20, "end": 28, "id": 4}, {"text": "microscopy", "start": 29, "end": 39, "id": 5}, {"text": "(", "start": 40, "end": 41, "id": 6}, {"text": "SEM", "start": 41, "end": 44, "id": 7}, {"text": ")", "start": 44, "end": 45, "id": 8}, {"text": "imaging", "start": 46, "end": 53, "id": 9}, {"text": "of", "start": 54, "end": 56, "id": 10}, {"text": "Devosia", "start": 57, "end": 64, "id": 11}, {"text": "mutans", "start": 65, "end": 71, "id": 12}, {"text": "17", "start": 72, "end": 74, "id": 13}, {"text": "-", "start": 74, "end": 75, "id": 14}, {"text": "2-E-8", "start": 75, "end": 80, "id": 15}, {"text": "(", "start": 81, "end": 82, "id": 16}, {"text": "A", "start": 82, "end": 83, "id": 17}, {"text": ")", "start": 83, "end": 84, "id": 18}, {"text": "and", "start": 85, "end": 88, "id": 19}, {"text": "transmission", "start": 89, "end": 101, "id": 20}, {"text": "electron", "start": 102, "end": 110, "id": 21}, {"text": "microscopy", "start": 111, "end": 121, "id": 22}, {"text": "(", "start": 122, "end": 123, "id": 23}, {"text": "TEM", "start": 123, "end": 126, "id": 24}, {"text": ")", "start": 126, "end": 127, "id": 25}, {"text": "images", "start": 128, "end": 134, "id": 26}, {"text": "(", "start": 135, "end": 136, "id": 27}, {"text": "B", "start": 136, "end": 137, "id": 28}, {"text": ",", "start": 137, "end": 138, "id": 29}, {"text": "C", "start": 138, "end": 139, "id": 30}, {"text": ")", "start": 139, "end": 140, "id": 31}, {"text": "of", "start": 141, "end": 143, "id": 32}, {"text": "isolate", "start": 144, "end": 151, "id": 33}, {"text": "17", "start": 152, "end": 154, "id": 34}, {"text": "-", "start": 154, "end": 155, "id": 35}, {"text": "2-E-8", "start": 155, "end": 160, "id": 36}, {"text": ".", "start": 160, "end": 161, "id": 37}]}
{"pdf_hash": "1ad621a0d41e2f1eac4ae3d75f9f5af4e3853020", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Figure 1. CT scans of a 45-year-old man with small cell carcinoma of the rectum (patient 4). (A) Axial non-enhanced CT scan demonstrating a thickened left wall of the rectum, with patchy low attenuation and the presence of an exophytic mass. Tumor invasion of the prostate glands and seminal vesicle was also observed. (B) Axial contrast-enhanced CT scan demonstrating heterogeneous strong enhancement. (C) Axial CT scan demonstrating the presence of multiple lung metastases. (D) Axial non-enhanced and contrast-enhanced CT scan demonstrating the presence of multiple liver metastases. 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{"pdf_hash": "334c684c32c80d491d815f0cc873120a99d9a7c3", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Magnetic resonance (MR) images. A. Coronal MR image showed a low attenuated on T1-weighted in the ventral tongue. B. A high attenuated on T2-weighted. Thus, we could concluded this lesion is consisted with fluid accumulation. Eun-Jung Kwak et al: Oral foregut cyst in the ventral tongue: a case report. J Korean Assoc Oral Maxillofac Surg 2014", "width": 1010, "height": 530, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [32, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "db3dc5c4-fa76-43e4-865c-2df201ce3daa", "label": "a", "points": [[15.2, 26.9], [15.2, 515.1], [479.5, 515.1], [479.5, 26.9]], "color": "yellow"}, {"id": "b47e0f57-2de2-479a-a7fe-6fcee8ad1256", "label": "b", "points": [[508.2, 26.9], [508.2, 518.3], [967.7, 518.3], [967.7, 26.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Magnetic", "start": 8, "end": 16, "id": 4}, {"text": "resonance", "start": 17, "end": 26, "id": 5}, {"text": "(", "start": 27, "end": 28, "id": 6}, {"text": "MR", "start": 28, "end": 30, "id": 7}, {"text": ")", "start": 30, "end": 31, "id": 8}, {"text": "images", "start": 32, "end": 38, "id": 9}, {"text": ".", "start": 38, "end": 39, "id": 10}, {"text": "A.", "start": 40, "end": 42, "id": 11}, {"text": "Coronal", "start": 43, "end": 50, "id": 12}, {"text": "MR", "start": 51, "end": 53, "id": 13}, {"text": "image", "start": 54, "end": 59, "id": 14}, {"text": "showed", "start": 60, "end": 66, "id": 15}, {"text": "a", "start": 67, "end": 68, "id": 16}, {"text": "low", "start": 69, "end": 72, "id": 17}, {"text": "attenuated", "start": 73, "end": 83, "id": 18}, {"text": "on", "start": 84, "end": 86, "id": 19}, {"text": "T1-weighted", "start": 87, "end": 98, "id": 20}, {"text": "in", "start": 99, "end": 101, "id": 21}, {"text": "the", "start": 102, "end": 105, "id": 22}, {"text": "ventral", "start": 106, "end": 113, "id": 23}, {"text": "tongue", "start": 114, "end": 120, "id": 24}, {"text": ".", "start": 120, "end": 121, "id": 25}, {"text": "B.", "start": 122, "end": 124, "id": 26}, {"text": "A", "start": 125, "end": 126, "id": 27}, {"text": "high", "start": 127, "end": 131, "id": 28}, {"text": "attenuated", "start": 132, "end": 142, "id": 29}, {"text": "on", "start": 143, "end": 145, "id": 30}, {"text": "T2-weighted", "start": 146, "end": 157, "id": 31}, {"text": ".", "start": 157, "end": 158, "id": 32}, {"text": "Thus", "start": 159, "end": 163, "id": 33}, {"text": ",", "start": 163, "end": 164, "id": 34}, {"text": "we", "start": 165, "end": 167, "id": 35}, {"text": "could", "start": 168, "end": 173, "id": 36}, {"text": "concluded", "start": 174, "end": 183, "id": 37}, {"text": "this", "start": 184, "end": 188, "id": 38}, {"text": "lesion", "start": 189, "end": 195, "id": 39}, {"text": "is", "start": 196, "end": 198, "id": 40}, {"text": "consisted", "start": 199, "end": 208, "id": 41}, {"text": "with", "start": 209, "end": 213, "id": 42}, {"text": "fluid", "start": 214, "end": 219, "id": 43}, {"text": "accumulation", "start": 220, "end": 232, "id": 44}, {"text": ".", "start": 232, "end": 233, "id": 45}, {"text": "Eun", "start": 234, "end": 237, "id": 46}, {"text": "-", "start": 237, "end": 238, "id": 47}, {"text": "Jung", "start": 238, "end": 242, "id": 48}, {"text": "Kwak", "start": 243, "end": 247, "id": 49}, {"text": "et", "start": 248, "end": 250, "id": 50}, {"text": "al", "start": 251, "end": 253, "id": 51}, {"text": ":", "start": 253, "end": 254, "id": 52}, {"text": "Oral", "start": 255, "end": 259, "id": 53}, {"text": "foregut", "start": 260, "end": 267, "id": 54}, {"text": "cyst", "start": 268, "end": 272, "id": 55}, {"text": "in", "start": 273, "end": 275, "id": 56}, {"text": "the", "start": 276, "end": 279, "id": 57}, {"text": "ventral", "start": 280, "end": 287, "id": 58}, {"text": "tongue", "start": 288, "end": 294, "id": 59}, {"text": ":", "start": 294, "end": 295, "id": 60}, {"text": "a", "start": 296, "end": 297, "id": 61}, {"text": "case", "start": 298, "end": 302, "id": 62}, {"text": "report", "start": 303, "end": 309, "id": 63}, {"text": ".", "start": 309, "end": 310, "id": 64}, {"text": "J", "start": 311, "end": 312, "id": 65}, {"text": "Korean", "start": 313, "end": 319, "id": 66}, {"text": "Assoc", "start": 320, "end": 325, "id": 67}, {"text": "Oral", "start": 326, "end": 330, "id": 68}, {"text": "Maxillofac", "start": 331, "end": 341, "id": 69}, {"text": "Surg", "start": 342, "end": 346, "id": 70}, {"text": "2014", "start": 347, "end": 351, "id": 71}]}
{"pdf_hash": "60915c91c63f7456d4e084c89ca9319c828d2402", "fig_key": "Figure1", "fig_uri": "6-Figure1-1.png", "text": "Fig. 1 a, b CT images are showing a lesion of 9.0\u00d76.5\u00d7 4.0 cm located on the right adrenal gland. c, d MRI images are showing a multi-cystic lesion on the right adrenal gland. All arrows are indicating the cystic lesion", "width": 1044, "height": 832, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "c": [32, 33, 34, 35, 36, 37, 38, 39, 40, 23, 24, 25, 26, 27, 28, 29, 30, 31], "d": [32, 33, 34, 35, 36, 37, 38, 39, 40, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "e3da772b-e21f-4d72-a317-4ba8004abeff", "label": "a", "points": [[28.5, 36.1], [28.5, 426.9], [518.3, 426.9], [518.3, 36.1]], "color": "yellow"}, {"id": "6b9ab85b-46ac-4c82-b5fa-c8a9f802ef5a", "label": "b", "points": [[556.3, 31.1], [556.3, 431.9], [1041.1, 431.9], [1041.1, 31.1]], "color": "cyan"}, {"id": "3096eba6-eb57-4e91-8e3e-9ed3de0852ec", "label": "c", "points": [[36.8, 441.8], [36.8, 822.7], [572.7, 822.7], [572.7, 441.8]], "color": "magenta"}, {"id": "5ad30c85-e403-4c04-87ec-5c9085f7c22c", "label": "d", "points": [[572.7, 436.8], [572.7, 822.7], [1042.8, 822.7], [1042.8, 436.8]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": ",", "start": 8, "end": 9, "id": 4}, {"text": "b", "start": 10, "end": 11, "id": 5}, {"text": "CT", "start": 12, "end": 14, "id": 6}, {"text": "images", "start": 15, "end": 21, "id": 7}, {"text": "are", "start": 22, "end": 25, "id": 8}, {"text": "showing", "start": 26, "end": 33, "id": 9}, {"text": "a", "start": 34, "end": 35, "id": 10}, {"text": "lesion", "start": 36, "end": 42, "id": 11}, {"text": "of", "start": 43, "end": 45, "id": 12}, {"text": "9.0\u00d76.5\u00d7", "start": 46, "end": 54, "id": 13}, {"text": "4.0", "start": 55, "end": 58, "id": 14}, {"text": "cm", "start": 59, "end": 61, "id": 15}, {"text": "located", "start": 62, "end": 69, "id": 16}, {"text": "on", "start": 70, "end": 72, "id": 17}, {"text": "the", "start": 73, "end": 76, "id": 18}, {"text": "right", "start": 77, "end": 82, "id": 19}, {"text": "adrenal", "start": 83, "end": 90, "id": 20}, {"text": "gland", "start": 91, "end": 96, "id": 21}, {"text": ".", "start": 96, "end": 97, "id": 22}, {"text": "c", "start": 98, "end": 99, "id": 23}, {"text": ",", "start": 99, "end": 100, "id": 24}, {"text": "d", "start": 101, "end": 102, "id": 25}, {"text": "MRI", "start": 103, "end": 106, "id": 26}, {"text": "images", "start": 107, "end": 113, "id": 27}, {"text": "are", "start": 114, "end": 117, "id": 28}, {"text": "showing", "start": 118, "end": 125, "id": 29}, {"text": "a", "start": 126, "end": 127, "id": 30}, {"text": "multi", "start": 128, "end": 133, "id": 31}, {"text": "-", "start": 133, "end": 134, "id": 32}, {"text": "cystic", "start": 134, "end": 140, "id": 33}, {"text": "lesion", "start": 141, "end": 147, "id": 34}, {"text": "on", "start": 148, "end": 150, "id": 35}, {"text": "the", "start": 151, "end": 154, "id": 36}, {"text": "right", "start": 155, "end": 160, "id": 37}, {"text": "adrenal", "start": 161, "end": 168, "id": 38}, {"text": "gland", "start": 169, "end": 174, "id": 39}, {"text": ".", "start": 174, "end": 175, "id": 40}, {"text": "All", "start": 176, "end": 179, "id": 41}, {"text": "arrows", "start": 180, "end": 186, "id": 42}, {"text": "are", "start": 187, "end": 190, "id": 43}, {"text": "indicating", "start": 191, "end": 201, "id": 44}, {"text": "the", "start": 202, "end": 205, "id": 45}, {"text": "cystic", "start": 206, "end": 212, "id": 46}, {"text": "lesion", "start": 213, "end": 219, "id": 47}]}
{"pdf_hash": "34f48fa29fc5c3121a53edd2e77a8f5d35965df1", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Findings from computed tomography. A: Unenhanced computed tomography (CT) shows a 16 mm \u00d7 15 mm, somewhat obscure cystic lesion (red arrow) in the pancreatic tail; B: Contrast-enhanced CT shows an 18 mm \u00d7 17 mm cystic lesion (red arrow) with a well-defined, hyper-enhanced, thin peripheral rim and a 6-mm nodule during the arterial phase; C: The outer rim appears iso-enhanced compared to normal pancreatic parenchyma during the portal venous phases (red arrow).", "width": 1284, "height": 356, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35], "b": [36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76], "c": [77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100]}, "subfigures": [{"id": "b21794b9-9b25-4956-8ff3-23dfbacda553", "label": "a", "points": [[7.2, -0.3], [7.2, 344.5], 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{"pdf_hash": "0e103a2307b0894b8d3e45c0079c8f2ebfb4b810", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Magnetic resonance imaging [T1-weighted (A) and fat-suppressed T2-weighted (B) coronal images] of the abdomen revealed multiple nodular or lobulated masses in the bilateral kidneys showing low signal intensity on T1-weighted image and inhomogeneous high signal intensity on T2-weighted image. There was also a lesion in the first lumbar (L1) vertebra showing similar but more inhomogeneous signal intensity (arrows).", "width": 1070, "height": 526, "subcaptions": {"a": [7, 8, 9, 10], "b": [12, 13, 14, 15, 16, 17, 18]}, "subfigures": [{"id": "448b5b4a-a24b-4ea2-b1f4-25388a927bec", "label": "a", "points": [[38.9, 20.3], [38.9, 491.9], [535.9, 491.9], [535.9, 20.3]], "color": "yellow"}, {"id": "c102c509-0e8d-4e91-b784-4d53c2ad2537", "label": "b", "points": [[540.9, 491.9], [540.9, 28.7], [1031.1, 28.7], [1031.1, 491.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Magnetic", "start": 10, "end": 18, "id": 3}, {"text": "resonance", "start": 19, "end": 28, "id": 4}, {"text": "imaging", "start": 29, "end": 36, "id": 5}, {"text": "[", "start": 37, "end": 38, "id": 6}, {"text": "T1-weighted", "start": 38, "end": 49, "id": 7}, {"text": "(", "start": 50, "end": 51, "id": 8}, {"text": "A", "start": 51, "end": 52, "id": 9}, {"text": ")", "start": 52, "end": 53, "id": 10}, {"text": "and", "start": 54, "end": 57, "id": 11}, {"text": "fat", "start": 58, "end": 61, "id": 12}, {"text": "-", "start": 61, "end": 62, "id": 13}, {"text": "suppressed", "start": 62, "end": 72, "id": 14}, {"text": "T2-weighted", "start": 73, "end": 84, "id": 15}, {"text": "(", "start": 85, "end": 86, "id": 16}, {"text": "B", "start": 86, "end": 87, "id": 17}, {"text": ")", "start": 87, "end": 88, "id": 18}, {"text": "coronal", "start": 89, "end": 96, "id": 19}, {"text": "images", "start": 97, "end": 103, "id": 20}, {"text": "]", "start": 103, "end": 104, "id": 21}, {"text": "of", "start": 105, "end": 107, "id": 22}, {"text": "the", "start": 108, "end": 111, "id": 23}, {"text": "abdomen", "start": 112, "end": 119, "id": 24}, {"text": "revealed", "start": 120, "end": 128, "id": 25}, {"text": "multiple", "start": 129, "end": 137, "id": 26}, {"text": "nodular", "start": 138, "end": 145, "id": 27}, {"text": "or", "start": 146, "end": 148, "id": 28}, {"text": "lobulated", "start": 149, "end": 158, "id": 29}, {"text": "masses", "start": 159, "end": 165, "id": 30}, {"text": "in", "start": 166, "end": 168, "id": 31}, {"text": "the", "start": 169, "end": 172, "id": 32}, {"text": "bilateral", "start": 173, "end": 182, "id": 33}, {"text": "kidneys", "start": 183, "end": 190, "id": 34}, {"text": "showing", "start": 191, "end": 198, "id": 35}, {"text": "low", "start": 199, "end": 202, "id": 36}, {"text": "signal", "start": 203, "end": 209, "id": 37}, {"text": "intensity", "start": 210, "end": 219, "id": 38}, {"text": "on", "start": 220, "end": 222, "id": 39}, {"text": "T1-weighted", "start": 223, "end": 234, "id": 40}, {"text": "image", "start": 235, "end": 240, "id": 41}, {"text": "and", "start": 241, "end": 244, "id": 42}, {"text": "inhomogeneous", "start": 245, "end": 258, "id": 43}, {"text": "high", "start": 259, "end": 263, "id": 44}, {"text": "signal", "start": 264, "end": 270, "id": 45}, {"text": "intensity", "start": 271, "end": 280, "id": 46}, {"text": "on", "start": 281, "end": 283, "id": 47}, {"text": "T2-weighted", "start": 284, "end": 295, "id": 48}, {"text": "image", "start": 296, "end": 301, "id": 49}, {"text": ".", "start": 301, "end": 302, "id": 50}, {"text": "There", "start": 303, "end": 308, "id": 51}, {"text": "was", "start": 309, "end": 312, "id": 52}, {"text": "also", "start": 313, "end": 317, "id": 53}, {"text": "a", "start": 318, "end": 319, "id": 54}, {"text": "lesion", "start": 320, "end": 326, "id": 55}, {"text": "in", "start": 327, "end": 329, "id": 56}, {"text": "the", "start": 330, "end": 333, "id": 57}, {"text": "first", "start": 334, "end": 339, "id": 58}, {"text": "lumbar", "start": 340, "end": 346, "id": 59}, {"text": "(", "start": 347, "end": 348, "id": 60}, {"text": "L1", "start": 348, "end": 350, "id": 61}, {"text": ")", "start": 350, "end": 351, "id": 62}, {"text": "vertebra", "start": 352, "end": 360, "id": 63}, {"text": "showing", "start": 361, "end": 368, "id": 64}, {"text": "similar", "start": 369, "end": 376, "id": 65}, {"text": "but", "start": 377, "end": 380, "id": 66}, {"text": "more", "start": 381, "end": 385, "id": 67}, {"text": "inhomogeneous", "start": 386, "end": 399, "id": 68}, {"text": "signal", "start": 400, "end": 406, "id": 69}, {"text": "intensity", "start": 407, "end": 416, "id": 70}, {"text": "(", "start": 417, "end": 418, "id": 71}, {"text": "arrows", "start": 418, "end": 424, "id": 72}, {"text": ")", "start": 424, "end": 425, "id": 73}, {"text": ".", "start": 425, "end": 426, "id": 74}]}
{"pdf_hash": "27d338e811d3aa7e47cb4a02c04ba19f231facb4", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. A 38-year-old man with pleural effusion who was diagnosed with pleural paragonimiasis. (A) Chest radiography showed pleural effusion. (B) Chest computed tomography showed pleural thickening with pleural effusion. (C) Subpleural consolidation.", "width": 1012, "height": 640, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "c": [40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "569a9ce0-460f-4001-bd94-28d07d050793", "label": "a", "points": [[8.9, 2.9], [8.9, 632.8], [536.4, 632.8], [536.4, 2.9]], "color": "yellow"}, {"id": "64f0490a-b2b8-4aae-b442-d68a2372d9d5", "label": "b", "points": [[552.4, 4.5], [552.4, 313.1], [972.8, 313.1], [972.8, 4.5]], "color": "cyan"}, {"id": "56038235-6a5d-4d8d-9a5e-fa1c973339b9", "label": "c", "points": [[554, 330.7], [554, 639.2], [969.6, 639.2], [969.6, 330.7]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "38-year", "start": 12, "end": 19, "id": 4}, {"text": "-", "start": 19, "end": 20, "id": 5}, {"text": "old", "start": 20, "end": 23, "id": 6}, {"text": "man", "start": 24, "end": 27, "id": 7}, {"text": "with", "start": 28, "end": 32, "id": 8}, {"text": "pleural", "start": 33, "end": 40, "id": 9}, {"text": "effusion", "start": 41, "end": 49, "id": 10}, {"text": "who", "start": 50, "end": 53, "id": 11}, {"text": "was", "start": 54, "end": 57, "id": 12}, {"text": "diagnosed", "start": 58, "end": 67, "id": 13}, {"text": "with", "start": 68, "end": 72, "id": 14}, {"text": "pleural", "start": 73, "end": 80, "id": 15}, {"text": "paragonimiasis", "start": 81, "end": 95, "id": 16}, {"text": ".", "start": 95, "end": 96, "id": 17}, {"text": "(", "start": 97, "end": 98, "id": 18}, {"text": "A", "start": 98, "end": 99, "id": 19}, {"text": ")", "start": 99, "end": 100, "id": 20}, {"text": "Chest", "start": 101, "end": 106, "id": 21}, {"text": "radiography", "start": 107, "end": 118, "id": 22}, {"text": "showed", "start": 119, "end": 125, "id": 23}, {"text": "pleural", "start": 126, "end": 133, "id": 24}, {"text": "effusion", "start": 134, "end": 142, "id": 25}, {"text": ".", "start": 142, "end": 143, "id": 26}, {"text": "(", "start": 144, "end": 145, "id": 27}, {"text": "B", "start": 145, "end": 146, "id": 28}, {"text": ")", "start": 146, "end": 147, "id": 29}, {"text": "Chest", "start": 148, "end": 153, "id": 30}, {"text": "computed", "start": 154, "end": 162, "id": 31}, {"text": "tomography", "start": 163, "end": 173, "id": 32}, {"text": "showed", "start": 174, "end": 180, "id": 33}, {"text": "pleural", "start": 181, "end": 188, "id": 34}, {"text": "thickening", "start": 189, "end": 199, "id": 35}, {"text": "with", "start": 200, "end": 204, "id": 36}, {"text": "pleural", "start": 205, "end": 212, "id": 37}, {"text": "effusion", "start": 213, "end": 221, "id": 38}, {"text": ".", "start": 221, "end": 222, "id": 39}, {"text": "(", "start": 223, "end": 224, "id": 40}, {"text": "C", "start": 224, "end": 225, "id": 41}, {"text": ")", "start": 225, "end": 226, "id": 42}, {"text": "Subpleural", "start": 227, "end": 237, "id": 43}, {"text": "consolidation", "start": 238, "end": 251, "id": 44}, {"text": ".", "start": 251, "end": 252, "id": 45}]}
{"pdf_hash": "fc59bc90c5362f86da26cb78ca722bbd299aaae8", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4 Usual MRI appearance of a SEMS-treated CRC. At diagnosis, sagittal CT image (a) shows an endoscopically impassable, ulcerated CRC of the sigmoid colon as segmental mural thickening (arrowhead). After stent placement, sagittal T2- (b) and coronal fat-saturated T1-weighted after intravenous gadolinium contrast (c) MRI images show well-expanded SEMS (thick arrows) with patent lumen devoid of signal, and mural thickening (arrowheads) with T2-hypersignal (b) and positive enhancement (b) corresponding to the treated tumour", "width": 1014, "height": 364, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102], "c": [41, 42, 43, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79]}, "subfigures": [{"id": "16db1f5c-bd31-413d-bb2c-af9abfff4be9", "label": "a", "points": [[36.1, 20.6], [36.1, 329.7], [340.5, 329.7], [340.5, 20.6]], "color": 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{"pdf_hash": "36c7034fc85510eee943d8781375b3bbbfc6a4de", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Figure 4 Some results of the automatic segmentation in \u2018typical\u2019 cases. The SAATs are enclosed by white contour lines. The MR pulse sequences were STIR, SE, FLAIR, and STIR for subfigures (a)\u2013(d), respectively. (a) The thickness of SAAT could be small compared with the abdominal diameters and arms can be seen in the field of view. (b) The backside inner boundary of SAAT was \u2018spiky\u2019 and the cross-section of an abdomen could look \u2018flat\u2019. (c) There was an umbilical discontinuity that made the inner and outer boundaries of the SAAT one. The thickness of SAAT could vary significantly with different locations on the same image slice. The cross-section of an abdomen could be like an inverted \u2018heart\u2019. (d) There might be low-signal areas inside SAAT. These were real nonadipose connective tissues such as fascia and not one of the imaging artefacts.", "width": 660, "height": 526, "subcaptions": {"a": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69], "b": [70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96], "c": [97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148], "d": [149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178]}, "subfigures": [{"id": "ae8f6337-2a4b-48fa-806a-6bf0d80ee33d", "label": "a", "points": [[2.6, 1.9], [2.6, 243.8], [319.6, 243.8], [319.6, 1.9]], "color": "yellow"}, {"id": 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{"pdf_hash": "bdbf6419e8b84f2cfd830d2a23e91c6ccde5c1e3", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. (A, B) Chest computed tomography shows a consolidative nodule (arrow) in a background of subpleural reticulation and honeycomb fibrosis at both lung bases. Positron emission tomography reveals 18 F-fluorodeoxyglucose uptake by the nodule. (C) The cut section of the lung showed an ill-defined and gray-tan colored mass (arrow). The background lung was emphysematous and fibrotic. (D-F) Histologic examination shows irregular interstitial fibrosis with patchy lymphoid aggregation, predominant lymphoplasmacytic infiltration, and occasional obliterative phlebitis. (G) The squamous cell carcinoma component shows keratinization and multifocal dyskeratosis. (H) The adenocarcinoma component was mainly composed of a moderately differentiated acinar pattern. 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{"pdf_hash": "19e41b34c6004a2aef8cb8cc97ca3b6d3cf1cbb4", "fig_key": "Figure7", "fig_uri": "10-Figure7-1.png", "text": "Figure 7. Connections of pegs to ribs and the presynaptic membrane. A: Two pegs (red) extend from a rib to the presynaptic membrane viewed in the transverse plane of an active zone. B,C: One or two pegs (red) are connected to each of the several ribs (gold) linked to a pair of primary docked vesicles viewed in the horizontal plane of the active zone. The viewpoint is deep to the ribs, which have been made transparent to show the contact sites of the pegs. D: Freeze-fracture replica from the presynaptic membrane of a mouse neuromuscular junction showing paired double rows of membrane macromolecules (from fig. 2, Fukuoka et al., 1987. Annals of Neurology 22:193-199, Copyright \u00a9 1987, Wiley-Blackwell, reproduced by permission). E: A surface model of the presynaptic membrane at an active zone with attached pegs viewed in the same plane and at the same scale as the freeze-fracture replica from the presynaptic membrane in D. The frequency and distribution of peg connection sites on the presynaptic membrane is similar to the frequency and distribution of macromolecules in the freeze-fracture replica of the membrane. 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{"pdf_hash": "edb25770e8bc7093a32021413361e8e9a2f6d1e7", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Figure 3. Patient 3. (A) Abdominal CT of an enlarged right adrenal gland, indicated by an arrow. (B) Abdominal CT of para-aortic lymph node swelling, indicated by an arrow. (C) Abdominal PET-CT with FDG uptake of right adrenal gland, indicated by an arrow. (D) Abdominal PET-CT of the para-aortic lymph node with FDG uptake, indicated by an arrow. (E) Alterations in the serum CEA levels of the patient. CT, computed tomography; PET, positron emission tomography; FDG, [18F]\u20112\u2011fluoro\u20112\u2011deoxy\u2011D\u2011glucose; CEA, serum carcinoembryonic antigen; UFT, tegaful/uracil; CPT-11, camptothecin-11; mFOLFOX6, modified FOLFOX6 regimen (5\u2011fluorouracil with leucovorin and oxaliplatin).", "width": 888, "height": 938, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22], "b": [23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "c": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60], "d": [61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83], "e": [84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141]}, "subfigures": [{"id": 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{"pdf_hash": "f0ef2d59c20036590f181156317b151d1b773921", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) (B) Chest CT showing intraluminal tumor (arrow) in the upper trachea. (C) (D) A bronchoscopic examination showing the non-pigmented flat tumor in the upper trachea.", "width": 978, "height": 822, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "c": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42], "d": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42]}, "subfigures": [{"id": "45d15493-d8b4-4cfa-b997-65cac8ec6425", "label": "a", "points": [[3.1, 71.1], [3.1, 403.3], [596.4, 403.3], [596.4, 71.1]], "color": "yellow"}, {"id": "257ac265-82c3-4571-9727-dd15c99d0212", "label": "b", "points": [[598.2, 33.1], [598.2, 404.3], [944.5, 404.3], [944.5, 33.1]], "color": "springgreen"}, {"id": "3fc68cbd-96ff-482f-abc2-1c60d62ff8d0", "label": "c", "points": [[386.3, 794.2], [386.3, 451.2], [0, 451.2], [0, 794.2]], "color": "magenta"}, {"id": "e24f858a-d3d5-4f70-9c3a-0e2ac6b4cb6c", "label": "d", "points": [[397, 449.6], [397, 795.8], [735.5, 795.8], [735.5, 449.6]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "(", "start": 14, "end": 15, "id": 6}, {"text": "B", "start": 15, "end": 16, "id": 7}, {"text": ")", "start": 16, "end": 17, "id": 8}, {"text": "Chest", "start": 18, "end": 23, "id": 9}, {"text": "CT", "start": 24, "end": 26, "id": 10}, {"text": "showing", "start": 27, "end": 34, "id": 11}, {"text": "intraluminal", "start": 35, "end": 47, "id": 12}, {"text": "tumor", "start": 48, "end": 53, "id": 13}, {"text": "(", "start": 54, "end": 55, "id": 14}, {"text": "arrow", "start": 55, "end": 60, "id": 15}, {"text": ")", "start": 60, "end": 61, "id": 16}, {"text": "in", "start": 62, "end": 64, "id": 17}, {"text": "the", "start": 65, "end": 68, "id": 18}, {"text": "upper", "start": 69, "end": 74, "id": 19}, {"text": "trachea", "start": 75, "end": 82, "id": 20}, {"text": ".", "start": 82, "end": 83, "id": 21}, {"text": "(", "start": 84, "end": 85, "id": 22}, {"text": "C", "start": 85, "end": 86, "id": 23}, {"text": ")", "start": 86, "end": 87, "id": 24}, {"text": "(", "start": 88, "end": 89, "id": 25}, {"text": "D", "start": 89, "end": 90, "id": 26}, {"text": ")", "start": 90, "end": 91, "id": 27}, {"text": "A", "start": 92, "end": 93, "id": 28}, {"text": "bronchoscopic", "start": 94, "end": 107, "id": 29}, {"text": "examination", "start": 108, "end": 119, "id": 30}, {"text": "showing", "start": 120, "end": 127, "id": 31}, {"text": "the", "start": 128, "end": 131, "id": 32}, {"text": "non", "start": 132, "end": 135, "id": 33}, {"text": "-", "start": 135, "end": 136, "id": 34}, {"text": "pigmented", "start": 136, "end": 145, "id": 35}, {"text": "flat", "start": 146, "end": 150, "id": 36}, {"text": "tumor", "start": 151, "end": 156, "id": 37}, {"text": "in", "start": 157, "end": 159, "id": 38}, {"text": "the", "start": 160, "end": 163, "id": 39}, {"text": "upper", "start": 164, "end": 169, "id": 40}, {"text": "trachea", "start": 170, "end": 177, "id": 41}, {"text": ".", "start": 177, "end": 178, "id": 42}]}
{"pdf_hash": "c0961f3844b9a52717fa68e4a70c78c1fd63acba", "fig_key": "Figure2", "fig_uri": "7-Figure2-1.png", "text": "Figure 2. MRI axial and sagittal FLAIR imaging. A, Pre-PCD axial T1 image at time of ataxia onset, 2 months prior to Purkinje cell cytoplasmic antibody type 1 diagnosis (5.5 years ago). Patient had known congenital dilatation of the lateral ventricles, particularly occipital horns. The size of the ventricles remained stable over years with no need for neurosurgical intervention. B, MRI was performed 9 months after onset of symptoms at time of most severe ataxia (5 years ago). It was diagnostic for PCD; T2 image shows cerebellar atrophy with enlargement of fourth ventricle. C, MRI T2 axial image 8 months after acute lymphocytic leukemia diagnosis at time of cytosine arabinoside encephalopathy (1 year ago). Cerebellar volume remained stable when compared to MRI 4 years prior. D, Sagittal image from MRI at onset of ataxia (corresponding to A). Cerebellar vermian volume appears normal. E, On the sagittal image (corresponding to B), there is notable progression of cerebellar vermian atrophy after progression of PCA-1 disease. F, The sagittal image from MRI 1 year ago (corresponding to C) shows no interval change after immunotherapy and systemic chemotherapy. Although only a single image can be shown here, when the entire 2 MRI studies (sagittal, axial, coronal images) were compared with our radiologist, they look remarkably similar, including the dimensions of the vermis and fovea. Despite the severe vermian volume loss, the patient has mild ataxia with minimal impact on the quality of daily life. 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{"pdf_hash": "bb8d199be5c1e42686ccd6893f55be1e97dec83c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 \u2013 Magnetic resonance imaging of Balo concentric sclerosis. (A) Axial and (B) sagittal T2-weighted FLAIR images show typical multilayered concentric ring lesion in the right centrum semiovale. (C) Cerebral blood flow map shows regional hypoperfusion with central minimally increased perfusion within the lesion. (D) Isotropic combined diffusion-weighted image and mean diffusivity map show a ring of relatively reduced diffusion along the rim of the lesion. 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{"pdf_hash": "f1b58678cd80075afd4052c7b8b2a01baa45e79f", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. (A) A 64-year-old man with pigment epithelial detachment (PED) secondary to age-related macular degeneration in right eye with subfoveal choroidal neovascularization was injected with conventional dose anti-vascular endothelial growth factor 28 times (ranibizumab 0.5 mg) during a 40-month period. Subfoveal PED persisted with no improvement of visual acuity. (B) Afterwards, bevacizumab 5.0 mg was injected monthly. 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{"pdf_hash": "65ab133d8296e93ac4a211088ee32de4511b8443", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. Magnetic resonance images in T2 sagittal (A) and T1 sagittal (B) images revealed a hyper-acute epidural hematoma over the T6 extending to the T10 vertebrae. Axial cuts showing epidural hematoma compressing the spinal cord (C). Arrows indicate the epidural hematoma. Axial cut showing polymethylmethacrylate in the left pedicle (D) (arrow).", "width": 1294, "height": 826, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "b": [3, 4, 5, 6, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34], "c": [35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "d": [64, 65, 66, 67, 68, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63]}, "subfigures": [{"id": "809e6b0d-aaa7-4de2-8beb-aa95ab52279a", "label": "a", "points": [[13.4, 14], [13.4, 792.8], [407.9, 792.8], [407.9, 14]], "color": "yellow"}, {"id": "d0d6b84c-89e3-4018-abe8-aef4879233f0", "label": "b", "points": [[416.1, 7.8], [416.1, 792.8], [888.2, 792.8], [888.2, 7.8]], "color": "cyan"}, {"id": "a291f159-5f88-4a5c-a82b-6bf4fe00bf91", "label": "c", "points": [[898.5, 16], [898.5, 396.2], [1290.9, 396.2], [1290.9, 16]], "color": "magenta"}, {"id": "00c25246-9aee-4b60-bb88-b70285687574", "label": "d", "points": [[900.5, 408.5], [900.5, 796.9], [1280.7, 796.9], [1280.7, 408.5]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Magnetic", "start": 10, "end": 18, "id": 3}, {"text": "resonance", "start": 19, "end": 28, "id": 4}, {"text": "images", "start": 29, "end": 35, "id": 5}, {"text": "in", "start": 36, "end": 38, "id": 6}, {"text": "T2", "start": 39, "end": 41, "id": 7}, {"text": "sagittal", "start": 42, "end": 50, "id": 8}, {"text": "(", "start": 51, "end": 52, "id": 9}, {"text": "A", "start": 52, "end": 53, "id": 10}, {"text": ")", "start": 53, "end": 54, "id": 11}, {"text": "and", "start": 55, "end": 58, "id": 12}, {"text": "T1", "start": 59, "end": 61, "id": 13}, {"text": "sagittal", "start": 62, "end": 70, "id": 14}, {"text": "(", "start": 71, "end": 72, "id": 15}, {"text": "B", "start": 72, "end": 73, "id": 16}, {"text": ")", "start": 73, "end": 74, "id": 17}, {"text": "images", "start": 75, "end": 81, "id": 18}, {"text": "revealed", "start": 82, "end": 90, "id": 19}, {"text": "a", "start": 91, "end": 92, "id": 20}, {"text": "hyper", "start": 93, "end": 98, "id": 21}, {"text": "-", "start": 98, "end": 99, "id": 22}, {"text": "acute", "start": 99, "end": 104, "id": 23}, {"text": "epidural", "start": 105, "end": 113, "id": 24}, {"text": "hematoma", "start": 114, "end": 122, "id": 25}, {"text": "over", "start": 123, "end": 127, "id": 26}, {"text": "the", "start": 128, "end": 131, "id": 27}, {"text": "T6", "start": 132, "end": 134, "id": 28}, {"text": "extending", "start": 135, "end": 144, "id": 29}, {"text": "to", "start": 145, "end": 147, "id": 30}, {"text": "the", "start": 148, "end": 151, "id": 31}, {"text": "T10", "start": 152, "end": 155, "id": 32}, {"text": "vertebrae", "start": 156, "end": 165, "id": 33}, {"text": ".", "start": 165, "end": 166, "id": 34}, {"text": "Axial", "start": 167, "end": 172, "id": 35}, {"text": "cuts", "start": 173, "end": 177, "id": 36}, {"text": "showing", "start": 178, "end": 185, "id": 37}, {"text": "epidural", "start": 186, "end": 194, "id": 38}, {"text": "hematoma", "start": 195, "end": 203, "id": 39}, {"text": "compressing", "start": 204, "end": 215, "id": 40}, {"text": "the", "start": 216, "end": 219, "id": 41}, {"text": "spinal", "start": 220, "end": 226, "id": 42}, {"text": "cord", "start": 227, "end": 231, "id": 43}, {"text": "(", "start": 232, "end": 233, "id": 44}, {"text": "C", "start": 233, "end": 234, "id": 45}, {"text": ")", "start": 234, "end": 235, "id": 46}, {"text": ".", "start": 235, "end": 236, "id": 47}, {"text": "Arrows", "start": 237, "end": 243, "id": 48}, {"text": "indicate", "start": 244, "end": 252, "id": 49}, {"text": "the", "start": 253, "end": 256, "id": 50}, {"text": "epidural", "start": 257, "end": 265, "id": 51}, {"text": "hematoma", "start": 266, "end": 274, "id": 52}, {"text": ".", "start": 274, "end": 275, "id": 53}, {"text": "Axial", "start": 276, "end": 281, "id": 54}, {"text": "cut", "start": 282, "end": 285, "id": 55}, {"text": "showing", "start": 286, "end": 293, "id": 56}, {"text": "polymethylmethacrylate", "start": 294, "end": 316, "id": 57}, {"text": "in", "start": 317, "end": 319, "id": 58}, {"text": "the", "start": 320, "end": 323, "id": 59}, {"text": "left", "start": 324, "end": 328, "id": 60}, {"text": "pedicle", "start": 329, "end": 336, "id": 61}, {"text": "(", "start": 337, "end": 338, "id": 62}, {"text": "D", "start": 338, "end": 339, "id": 63}, {"text": ")", "start": 339, "end": 340, "id": 64}, {"text": "(", "start": 341, "end": 342, "id": 65}, {"text": "arrow", "start": 342, "end": 347, "id": 66}, {"text": ")", "start": 347, "end": 348, "id": 67}, {"text": ".", "start": 348, "end": 349, "id": 68}]}
{"pdf_hash": "076f12a4001a50130f3d64a27bc14d8db56cad7b", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2. Reveals a high bifurcation of the basilar artery complicated with atherosclerosis and posterior circulation infarction. The patient is 85-year-old man. A, Reconstruction MRA image of maximum density projection of cerebral vessels, from the anterior-to-posterior view. The cerebral artery presents with atherosclerotic changes, the vertebrobasilar artery significantly deviates to right, showing an S shape, reaching the left CP corner area (grade 3). B, TOF reconstruction image of the coronal surface, the basilar artery bifurcation reaches the level of the middle of the third ventricle (grade 3). C, Cross-sectional TOF image. The basilar artery signals are uneven, suggesting mural macro thrombi and atherosclerosis, with a diameter of 8.3 mm. D, E, Cross-sectional SWI images. D, It reveals low mural signal, suggesting mural thrombi (white arrow). 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{"pdf_hash": "c4b08d34ad351b3b13e9b3317dd5d20c0ad7dfc1", "fig_key": "Figure2", "fig_uri": "5-Figure2-1.png", "text": "FIGURE 2 | DiI labeling of the magnocellular hypothalamic neurons in coronal sections. Low-magnification photomicrographs of the coronal sections of the hypothalamus showing retrograde DiI labeling of the neurons following DiI insertions into the posterior (A,B,C,D) and intermediate pituitary lobes on different prenatal stages. (A) E15, neurons in the supraoptic nucleus (SO) and wide space of the anterior hypothalamus. (B) E20, magnocellular neurons in SO. (C) E19, magnocellular neurons in the paraventricular nuclei (PV). (D) P9, neurons in the dorsolateral accessory nucleus. (E) P10, neurons in the periventricular hypothalamic nucleus after DiI insertion in the intermediate pituitary lobe. 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{"pdf_hash": "68b57d1523af26017652e4a11f7a5445627980a5", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "FIG. 3. Empty CTN phantom imaged with CT. (a) Coronal slice of empty CTN phantom. (b) Region-growing-based segmentation results. In this case, only inserts 1, 2, 4, and 8 are shown. [Color figure can be viewed at wileyonlinelibrary.com]", "width": 976, "height": 434, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "31e604d1-c4fa-40ed-888f-c6353777f079", "label": "a", "points": [[38.6, 4.4], [38.6, 397.5], [481.1, 397.5], [481.1, 4.4]], "color": "yellow"}, {"id": "75a6b648-4ecd-4fea-9115-42465791758d", "label": "b", "points": [[504.2, 2.8], [504.2, 402.2], [943.7, 402.2], [943.7, 2.8]], "color": "cyan"}], "tokens": [{"text": "FIG", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Empty", "start": 8, "end": 13, "id": 4}, {"text": "CTN", "start": 14, "end": 17, "id": 5}, {"text": "phantom", "start": 18, "end": 25, "id": 6}, {"text": "imaged", "start": 26, "end": 32, "id": 7}, {"text": "with", "start": 33, "end": 37, "id": 8}, {"text": "CT", "start": 38, "end": 40, "id": 9}, {"text": ".", "start": 40, "end": 41, "id": 10}, {"text": "(", "start": 42, "end": 43, "id": 11}, {"text": "a", "start": 43, "end": 44, "id": 12}, {"text": ")", "start": 44, "end": 45, "id": 13}, {"text": "Coronal", "start": 46, "end": 53, "id": 14}, {"text": "slice", "start": 54, "end": 59, "id": 15}, {"text": "of", "start": 60, "end": 62, "id": 16}, {"text": "empty", "start": 63, "end": 68, "id": 17}, {"text": "CTN", "start": 69, "end": 72, "id": 18}, {"text": "phantom", "start": 73, "end": 80, "id": 19}, {"text": ".", "start": 80, "end": 81, "id": 20}, {"text": "(", "start": 82, "end": 83, "id": 21}, {"text": "b", "start": 83, "end": 84, "id": 22}, {"text": ")", "start": 84, "end": 85, "id": 23}, {"text": "Region", "start": 86, "end": 92, "id": 24}, {"text": "-", "start": 92, "end": 93, "id": 25}, {"text": "growing", "start": 93, "end": 100, "id": 26}, {"text": "-", "start": 100, "end": 101, "id": 27}, {"text": "based", "start": 101, "end": 106, "id": 28}, {"text": "segmentation", "start": 107, "end": 119, "id": 29}, {"text": "results", "start": 120, "end": 127, "id": 30}, {"text": ".", "start": 127, "end": 128, "id": 31}, {"text": "In", "start": 129, "end": 131, "id": 32}, {"text": "this", "start": 132, "end": 136, "id": 33}, {"text": "case", "start": 137, "end": 141, "id": 34}, {"text": ",", "start": 141, "end": 142, "id": 35}, {"text": "only", "start": 143, "end": 147, "id": 36}, {"text": "inserts", "start": 148, "end": 155, "id": 37}, {"text": "1", "start": 156, "end": 157, "id": 38}, {"text": ",", "start": 157, "end": 158, "id": 39}, {"text": "2", "start": 159, "end": 160, "id": 40}, {"text": ",", "start": 160, "end": 161, "id": 41}, {"text": "4", "start": 162, "end": 163, "id": 42}, {"text": ",", "start": 163, "end": 164, "id": 43}, {"text": "and", "start": 165, "end": 168, "id": 44}, {"text": "8", "start": 169, "end": 170, "id": 45}, {"text": "are", "start": 171, "end": 174, "id": 46}, {"text": "shown", "start": 175, "end": 180, "id": 47}, {"text": ".", "start": 180, "end": 181, "id": 48}, {"text": "[", "start": 182, "end": 183, "id": 49}, {"text": "Color", "start": 183, "end": 188, "id": 50}, {"text": "figure", "start": 189, "end": 195, "id": 51}, {"text": "can", "start": 196, "end": 199, "id": 52}, {"text": "be", "start": 200, "end": 202, "id": 53}, {"text": "viewed", "start": 203, "end": 209, "id": 54}, {"text": "at", "start": 210, "end": 212, "id": 55}, {"text": "wileyonlinelibrary.com", "start": 213, "end": 235, "id": 56}, {"text": "]", "start": 235, "end": 236, "id": 57}]}
{"pdf_hash": "04e6cb0deeee070a227ded2e92904e14446aa33d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2 Extensive transmural inferior (arrows) wall chronic myocardial infarction assessed using dual energy delayed enhancement computed CT at low (50 keV) energy levels, both using grayscale (A) and color-coded (B) images. Dotted arrows depict an area of subendocardial necrosis. Rest SPECT images confirm the findings (C).", "width": 1402, "height": 428, "subcaptions": {"a": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "c": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "e20b167b-237f-4f03-bed6-ca90fe96a42d", "label": "a", "points": [[5.6, 1.9], [5.6, 389.4], [479.6, 389.4], [479.6, 1.9]], "color": "yellow"}, {"id": "ba77a24b-cf82-4297-afd7-8117d71ada61", "label": "b", "points": [[501.7, 1.9], [501.7, 391.7], [955.8, 391.7], [955.8, 1.9]], "color": "cyan"}, {"id": "1b3dc96a-4a11-4cca-8b9f-99581cafd4b0", "label": "c", "points": [[969.1, 4.1], [969.1, 391.7], [1396.5, 391.7], [1396.5, 4.1]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Extensive", "start": 9, "end": 18, "id": 2}, {"text": "transmural", "start": 19, "end": 29, "id": 3}, {"text": "inferior", "start": 30, "end": 38, "id": 4}, {"text": "(", "start": 39, "end": 40, "id": 5}, {"text": "arrows", "start": 40, "end": 46, "id": 6}, {"text": ")", "start": 46, "end": 47, "id": 7}, {"text": "wall", "start": 48, "end": 52, "id": 8}, {"text": "chronic", "start": 53, "end": 60, "id": 9}, {"text": "myocardial", "start": 61, "end": 71, "id": 10}, {"text": "infarction", "start": 72, "end": 82, "id": 11}, {"text": "assessed", "start": 83, "end": 91, "id": 12}, {"text": "using", "start": 92, "end": 97, "id": 13}, {"text": "dual", "start": 98, "end": 102, "id": 14}, {"text": "energy", "start": 103, "end": 109, "id": 15}, {"text": "delayed", "start": 110, "end": 117, "id": 16}, {"text": "enhancement", "start": 118, "end": 129, "id": 17}, {"text": "computed", "start": 130, "end": 138, "id": 18}, {"text": "CT", "start": 139, "end": 141, "id": 19}, {"text": "at", "start": 142, "end": 144, "id": 20}, {"text": "low", "start": 145, "end": 148, "id": 21}, {"text": "(", "start": 149, "end": 150, "id": 22}, {"text": "50", "start": 150, "end": 152, "id": 23}, {"text": "keV", "start": 153, "end": 156, "id": 24}, {"text": ")", "start": 156, "end": 157, "id": 25}, {"text": "energy", "start": 158, "end": 164, "id": 26}, {"text": "levels", "start": 165, "end": 171, "id": 27}, {"text": ",", "start": 171, "end": 172, "id": 28}, {"text": "both", "start": 173, "end": 177, "id": 29}, {"text": "using", "start": 178, "end": 183, "id": 30}, {"text": "grayscale", "start": 184, "end": 193, "id": 31}, {"text": "(", "start": 194, "end": 195, "id": 32}, {"text": "A", "start": 195, "end": 196, "id": 33}, {"text": ")", "start": 196, "end": 197, "id": 34}, {"text": "and", "start": 198, "end": 201, "id": 35}, {"text": "color", "start": 202, "end": 207, "id": 36}, {"text": "-", "start": 207, "end": 208, "id": 37}, {"text": "coded", "start": 208, "end": 213, "id": 38}, {"text": "(", "start": 214, "end": 215, "id": 39}, {"text": "B", "start": 215, "end": 216, "id": 40}, {"text": ")", "start": 216, "end": 217, "id": 41}, {"text": "images", "start": 218, "end": 224, "id": 42}, {"text": ".", "start": 224, "end": 225, "id": 43}, {"text": "Dotted", "start": 226, "end": 232, "id": 44}, {"text": "arrows", "start": 233, "end": 239, "id": 45}, {"text": "depict", "start": 240, "end": 246, "id": 46}, {"text": "an", "start": 247, "end": 249, "id": 47}, {"text": "area", "start": 250, "end": 254, "id": 48}, {"text": "of", "start": 255, "end": 257, "id": 49}, {"text": "subendocardial", "start": 258, "end": 272, "id": 50}, {"text": "necrosis", "start": 273, "end": 281, "id": 51}, {"text": ".", "start": 281, "end": 282, "id": 52}, {"text": "Rest", "start": 283, "end": 287, "id": 53}, {"text": "SPECT", "start": 288, "end": 293, "id": 54}, {"text": "images", "start": 294, "end": 300, "id": 55}, {"text": "confirm", "start": 301, "end": 308, "id": 56}, {"text": "the", "start": 309, "end": 312, "id": 57}, {"text": "findings", "start": 313, "end": 321, "id": 58}, {"text": "(", "start": 322, "end": 323, "id": 59}, {"text": "C", "start": 323, "end": 324, "id": 60}, {"text": ")", "start": 324, "end": 325, "id": 61}, {"text": ".", "start": 325, "end": 326, "id": 62}]}
{"pdf_hash": "28dc7b12b50bcfd2d0c328d976f10efb42c42e00", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1: Chest radiography findings. (a) Chest radiography showed no abnormal shadow. (b) Four years later, a large mass was observed in the right inferior mediastinum (arrow).", "width": 652, "height": 358, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16], "b": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]}, "subfigures": [{"id": "7c8d88dc-6c14-45f7-879c-53744d3094d7", "label": "a", "points": [[10.6, 4], [10.6, 328.4], [320.6, 328.4], [320.6, 4]], "color": "yellow"}, {"id": "5a6fd4b6-f4c5-4217-b2f7-3d52fe7ba24e", "label": "b", "points": [[322.7, 5], [322.7, 322.2], [647.1, 322.2], [647.1, 5]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "Chest", "start": 10, "end": 15, "id": 3}, {"text": "radiography", "start": 16, "end": 27, "id": 4}, {"text": "findings", "start": 28, "end": 36, "id": 5}, {"text": ".", "start": 36, "end": 37, "id": 6}, {"text": "(", "start": 38, "end": 39, "id": 7}, {"text": "a", "start": 39, "end": 40, "id": 8}, {"text": ")", "start": 40, "end": 41, "id": 9}, {"text": "Chest", "start": 42, "end": 47, "id": 10}, {"text": "radiography", "start": 48, "end": 59, "id": 11}, {"text": "showed", "start": 60, "end": 66, "id": 12}, {"text": "no", "start": 67, "end": 69, "id": 13}, {"text": "abnormal", "start": 70, "end": 78, "id": 14}, {"text": "shadow", "start": 79, "end": 85, "id": 15}, {"text": ".", "start": 85, "end": 86, "id": 16}, {"text": "(", "start": 87, "end": 88, "id": 17}, {"text": "b", "start": 88, "end": 89, "id": 18}, {"text": ")", "start": 89, "end": 90, "id": 19}, {"text": "Four", "start": 91, "end": 95, "id": 20}, {"text": "years", "start": 96, "end": 101, "id": 21}, {"text": "later", "start": 102, "end": 107, "id": 22}, {"text": ",", "start": 107, "end": 108, "id": 23}, {"text": "a", "start": 109, "end": 110, "id": 24}, {"text": "large", "start": 111, "end": 116, "id": 25}, {"text": "mass", "start": 117, "end": 121, "id": 26}, {"text": "was", "start": 122, "end": 125, "id": 27}, {"text": "observed", "start": 126, "end": 134, "id": 28}, {"text": "in", "start": 135, "end": 137, "id": 29}, {"text": "the", "start": 138, "end": 141, "id": 30}, {"text": "right", "start": 142, "end": 147, "id": 31}, {"text": "inferior", "start": 148, "end": 156, "id": 32}, {"text": "mediastinum", "start": 157, "end": 168, "id": 33}, {"text": "(", "start": 169, "end": 170, "id": 34}, {"text": "arrow", "start": 170, "end": 175, "id": 35}, {"text": ")", "start": 175, "end": 176, "id": 36}, {"text": ".", "start": 176, "end": 177, "id": 37}]}
{"pdf_hash": "a8e9091d9a70ea7cc5a8702215cc6ba27a347469", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. CT findings 2 months before death. The part of the tumor receiving radiotherapy (ar row) (a) and the part that did not receive radiotherapy (b).", "width": 1034, "height": 400, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [32, 33, 34, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "9aea8eef-7a1e-4a74-9b21-dfb87e3364a6", "label": "a", "points": [[32.9, 3.8], [32.9, 369.7], [524.7, 369.7], [524.7, 3.8]], "color": "yellow"}, {"id": "d1578f7a-56f1-4aab-b23b-87eb9daf7580", "label": "b", "points": [[531.2, 3.8], [531.2, 363.2], [1014.8, 363.2], [1014.8, 3.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "CT", "start": 10, "end": 12, "id": 3}, {"text": "findings", "start": 13, "end": 21, "id": 4}, {"text": "2", "start": 22, "end": 23, "id": 5}, {"text": "months", "start": 24, "end": 30, "id": 6}, {"text": "before", "start": 31, "end": 37, "id": 7}, {"text": "death", "start": 38, "end": 43, "id": 8}, {"text": ".", "start": 43, "end": 44, "id": 9}, {"text": "The", "start": 45, "end": 48, "id": 10}, {"text": "part", "start": 49, "end": 53, "id": 11}, {"text": "of", "start": 54, "end": 56, "id": 12}, {"text": "the", "start": 57, "end": 60, "id": 13}, {"text": "tumor", "start": 61, "end": 66, "id": 14}, {"text": "receiving", "start": 67, "end": 76, "id": 15}, {"text": "radiotherapy", "start": 77, "end": 89, "id": 16}, {"text": "(", "start": 90, "end": 91, "id": 17}, {"text": "ar", "start": 91, "end": 93, "id": 18}, {"text": "row", "start": 94, "end": 97, "id": 19}, {"text": ")", "start": 97, "end": 98, "id": 20}, {"text": "(", "start": 99, "end": 100, "id": 21}, {"text": "a", "start": 100, "end": 101, "id": 22}, {"text": ")", "start": 101, "end": 102, "id": 23}, {"text": "and", "start": 103, "end": 106, "id": 24}, {"text": "the", "start": 107, "end": 110, "id": 25}, {"text": "part", "start": 111, "end": 115, "id": 26}, {"text": "that", "start": 116, "end": 120, "id": 27}, {"text": "did", "start": 121, "end": 124, "id": 28}, {"text": "not", "start": 125, "end": 128, "id": 29}, {"text": "receive", "start": 129, "end": 136, "id": 30}, {"text": "radiotherapy", "start": 137, "end": 149, "id": 31}, {"text": "(", "start": 150, "end": 151, "id": 32}, {"text": "b", "start": 151, "end": 152, "id": 33}, {"text": ")", "start": 152, "end": 153, "id": 34}, {"text": ".", "start": 153, "end": 154, "id": 35}]}
{"pdf_hash": "52ed309808af35a40b661467ae3f2bb83482c77a", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5. Histological examination of CAR- or d-galN-primed endotoxin shock-induced mice liver. (A) LPS (20 mg/mouse) was administered i.v. to CAR (5 mg/mouse)-primed C57BL/6 mice, and 12 h later, the livers were extirpated from these mice. (B) LPS (0.5 mg/mouse) was administered i.v. to D-galN (20 mg/mouse)-primed C57BL/6 mice. The livers were extirpated after 6 h of LPS injection. (C) Untreated mice were used as negative control. The extirpated livers were fixed in 10%- formaldehyde neutral buffer solution and embedded in paraffin; thin sections were cut and stained with hematoxylin-eosin. Arrow and arrow head represent chromatin aggregation and nuclear fragmentation, respectively. 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{"pdf_hash": "d247436f9b0d364ef9bbc9791197188497be9ac9", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "FIGURE 1 | Anatomical landmarks on the human supratemporal plane. (A) Lateral view of the left hemisphere, with STG indicated in red. (B\u2013D) Top view of left supratemporal plane, after removal of a large part of the parietal cortex. PP, HG, and PT are indicated in blue, yellow, and green, respectively. Major sulci are outlined in black (FTS, first transverse sulcus; SI, sulcus intermediate; HS, Heschl\u2019s sulcus; HS1, first Heschl\u2019s sulcus; HS2, second Heschl\u2019s sulcus). 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{"pdf_hash": "325f56245849aa4c30c57519008e4e60d98343f4", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "FIGURE 3 3D architecture of the nucleus. (a) Volume-rendered 3D image of a whole, unstained nucleus. (b) Nuclear substructures of chromatin region (blue), nucleolus (~330 nm in red), condensed chromatin (~340 nm in green), and nuclear bodies or speckles (~80 nm in cyan). (c and d) Side and top views of the nucleus are shown. To visualize the nuclear substructures clearly, the nuclear envelope is not displayed. 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{"pdf_hash": "decfe88c9fbfcef19bb8176c029eb164effe27f0", "fig_key": "Figure2", "fig_uri": "9-Figure2-1.png", "text": "Figure 2 Brain MRI. T2-weighted brain MRI in the axial (A and B) and sagittal (C and D) plane showing marked cerebellar atrophy and generalised cerebral atrophy.", "width": 1076, "height": 938, "subcaptions": {"a": [10, 11, 12, 13, 14, 15], "b": [10, 11, 12, 13, 14, 15], "c": [17, 18, 19, 20, 21, 22], "d": [17, 18, 19, 20, 21, 22]}, "subfigures": [{"id": "a6fa1be2-44f6-40fe-b3e8-1edaee273fa4", "label": "a", "points": [[46.2, 34.6], [46.2, 439.1], [517, 439.1], [517, 34.6]], "color": "yellow"}, {"id": "888aed23-713b-4897-90ca-62b823271697", "label": "b", "points": [[569.7, 29.5], [569.7, 444.2], [1047.4, 444.2], [1047.4, 29.5]], "color": "cyan"}, {"id": "3026da4e-db77-4655-a5bd-e8ce10a8a173", "label": "c", "points": [[41.1, 498.6], [41.1, 904.9], [523.8, 904.9], [523.8, 498.6]], "color": "magenta"}, {"id": "6125ec01-0534-4114-9c04-6bd637a6ed4e", "label": "d", "points": [[559.5, 512.2], [559.5, 901.5], [1045.7, 901.5], [1045.7, 512.2]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": "Brain", "start": 9, "end": 14, "id": 2}, {"text": "MRI", "start": 15, "end": 18, "id": 3}, {"text": ".", "start": 18, "end": 19, "id": 4}, {"text": "T2-weighted", "start": 20, "end": 31, "id": 5}, {"text": "brain", "start": 32, "end": 37, "id": 6}, {"text": "MRI", "start": 38, "end": 41, "id": 7}, {"text": "in", "start": 42, "end": 44, "id": 8}, {"text": "the", "start": 45, "end": 48, "id": 9}, {"text": "axial", "start": 49, "end": 54, "id": 10}, {"text": "(", "start": 55, "end": 56, "id": 11}, {"text": "A", "start": 56, "end": 57, "id": 12}, {"text": "and", "start": 58, "end": 61, "id": 13}, {"text": "B", "start": 62, "end": 63, "id": 14}, {"text": ")", "start": 63, "end": 64, "id": 15}, {"text": "and", "start": 65, "end": 68, "id": 16}, {"text": "sagittal", "start": 69, "end": 77, "id": 17}, {"text": "(", "start": 78, "end": 79, "id": 18}, {"text": "C", "start": 79, "end": 80, "id": 19}, {"text": "and", "start": 81, "end": 84, "id": 20}, {"text": "D", "start": 85, "end": 86, "id": 21}, {"text": ")", "start": 86, "end": 87, "id": 22}, {"text": "plane", "start": 88, "end": 93, "id": 23}, {"text": "showing", "start": 94, "end": 101, "id": 24}, {"text": "marked", "start": 102, "end": 108, "id": 25}, {"text": "cerebellar", "start": 109, "end": 119, "id": 26}, {"text": "atrophy", "start": 120, "end": 127, "id": 27}, {"text": "and", "start": 128, "end": 131, "id": 28}, {"text": "generalised", "start": 132, "end": 143, "id": 29}, {"text": "cerebral", "start": 144, "end": 152, "id": 30}, {"text": "atrophy", "start": 153, "end": 160, "id": 31}, {"text": ".", "start": 160, "end": 161, "id": 32}]}
{"pdf_hash": "4169d2d34a1a1b9f7c1999659ec9aa8052f508d8", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 Radiological images of the pituitary lesion and metastatic deposits. a Sagittal section of MRI pituitary post gadolinium showing suprasellar mass and extra-axial metastatic deposit in the posterior fossa with extension into the left hypoglossal canal. b MRI axial sequence post gadolinium showing the intradural extra-medullary cervical metastatic deposit at the level C3/C4", "width": 1018, "height": 452, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "b": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "82a7977d-6e55-4f73-95a5-5ac7da8a2c17", "label": "a", "points": [[15.3, 7.8], [15.3, 443.6], [552.5, 443.6], [552.5, 7.8]], "color": "yellow"}, {"id": "c596c669-c485-4d6d-994d-ec0e1d847d2b", "label": "b", "points": [[565.3, 9.4], [565.3, 443.6], [1010.8, 443.6], [1010.8, 9.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Radiological", "start": 7, "end": 19, "id": 3}, {"text": "images", "start": 20, "end": 26, "id": 4}, {"text": "of", "start": 27, "end": 29, "id": 5}, {"text": "the", "start": 30, "end": 33, "id": 6}, {"text": "pituitary", "start": 34, "end": 43, "id": 7}, {"text": "lesion", "start": 44, "end": 50, "id": 8}, {"text": "and", "start": 51, "end": 54, "id": 9}, {"text": "metastatic", "start": 55, "end": 65, "id": 10}, {"text": "deposits", "start": 66, "end": 74, "id": 11}, {"text": ".", "start": 74, "end": 75, "id": 12}, {"text": "a", "start": 76, "end": 77, "id": 13}, {"text": "Sagittal", "start": 78, "end": 86, "id": 14}, {"text": "section", "start": 87, "end": 94, "id": 15}, {"text": "of", "start": 95, "end": 97, "id": 16}, {"text": "MRI", "start": 98, "end": 101, "id": 17}, {"text": "pituitary", "start": 102, "end": 111, "id": 18}, {"text": "post", "start": 112, "end": 116, "id": 19}, {"text": "gadolinium", "start": 117, "end": 127, "id": 20}, {"text": "showing", "start": 128, "end": 135, "id": 21}, {"text": "suprasellar", "start": 136, "end": 147, "id": 22}, {"text": "mass", "start": 148, "end": 152, "id": 23}, {"text": "and", "start": 153, "end": 156, "id": 24}, {"text": "extra", "start": 157, "end": 162, "id": 25}, {"text": "-", "start": 162, "end": 163, "id": 26}, {"text": "axial", "start": 163, "end": 168, "id": 27}, {"text": "metastatic", "start": 169, "end": 179, "id": 28}, {"text": "deposit", "start": 180, "end": 187, "id": 29}, {"text": "in", "start": 188, "end": 190, "id": 30}, {"text": "the", "start": 191, "end": 194, "id": 31}, {"text": "posterior", "start": 195, "end": 204, "id": 32}, {"text": "fossa", "start": 205, "end": 210, "id": 33}, {"text": "with", "start": 211, "end": 215, "id": 34}, {"text": "extension", "start": 216, "end": 225, "id": 35}, {"text": "into", "start": 226, "end": 230, "id": 36}, {"text": "the", "start": 231, "end": 234, "id": 37}, {"text": "left", "start": 235, "end": 239, "id": 38}, {"text": "hypoglossal", "start": 240, "end": 251, "id": 39}, {"text": "canal", "start": 252, "end": 257, "id": 40}, {"text": ".", "start": 257, "end": 258, "id": 41}, {"text": "b", "start": 259, "end": 260, "id": 42}, {"text": "MRI", "start": 261, "end": 264, "id": 43}, {"text": "axial", "start": 265, "end": 270, "id": 44}, {"text": "sequence", "start": 271, "end": 279, "id": 45}, {"text": "post", "start": 280, "end": 284, "id": 46}, {"text": "gadolinium", "start": 285, "end": 295, "id": 47}, {"text": "showing", "start": 296, "end": 303, "id": 48}, {"text": "the", "start": 304, "end": 307, "id": 49}, {"text": "intradural", "start": 308, "end": 318, "id": 50}, {"text": "extra", "start": 319, "end": 324, "id": 51}, {"text": "-", "start": 324, "end": 325, "id": 52}, {"text": "medullary", "start": 325, "end": 334, "id": 53}, {"text": "cervical", "start": 335, "end": 343, "id": 54}, {"text": "metastatic", "start": 344, "end": 354, "id": 55}, {"text": "deposit", "start": 355, "end": 362, "id": 56}, {"text": "at", "start": 363, "end": 365, "id": 57}, {"text": "the", "start": 366, "end": 369, "id": 58}, {"text": "level", "start": 370, "end": 375, "id": 59}, {"text": "C3", "start": 376, "end": 378, "id": 60}, {"text": "/", "start": 378, "end": 379, "id": 61}, {"text": "C4", "start": 379, "end": 381, "id": 62}]}
{"pdf_hash": "b6e2aea356b1a22bc0501ac5ce019b2e51648a20", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4 In a 48-year-old man with acute aortic dissection, CT image at the level of the distal descending aorta (A) shows a posterior false lumen [F] and a competent partially collapsed anterior true lumen [T]. As the true and false lumens are traced from slice to slice from the chest (A) to the abdomen (B), the true lumen has collapsed completely and the false lumen now occupies nearly the entire aortic crosssection. Both celiac and SMA origins were covered by the dissection flap, which has collapsed up against the front wall of the aorta. The patient arrested and died in the Emergency Department before he could be transported to the angiography suite. 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{"pdf_hash": "67d70a70fd1daf48ce864df4ed8f49f8bbb79c8d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "FIGURE 2: AP and lateral X-ray", "width": 1070, "height": 668, "subcaptions": {"a": [3], "b": [5]}, "subfigures": [{"id": "cb1e459d-807c-45f4-b72b-3b65747c71df", "label": "a", "points": [[17.4, 1.5], [17.4, 660.7], [531.2, 660.7], [531.2, 1.5]], "color": "yellow"}, {"id": "f0824f2d-17e1-44d2-a3c9-e53ab525d756", "label": "b", "points": [[571.8, 3.2], [571.8, 662.4], [1058.6, 662.4], [1058.6, 3.2]], "color": "cyan"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, "end": 9, "id": 2}, {"text": "AP", "start": 10, "end": 12, "id": 3}, {"text": "and", "start": 13, "end": 16, "id": 4}, {"text": "lateral", "start": 17, "end": 24, "id": 5}, {"text": "X", "start": 25, "end": 26, "id": 6}, {"text": "-", "start": 26, "end": 27, "id": 7}, {"text": "ray", "start": 27, "end": 30, "id": 8}]}
{"pdf_hash": "8362605335cff339c785ff3c53dbd242e7a7d576", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1 a A cylindrical ROI was positioned manually in the left ventricle (LV) to obtain the time activity curves, LV(t), from the early phase images of the dynamic 11C-acetate PET data. b A whole myocardial ROI was set semi-automatically to obtain the time activity curves from myocardium, R(t), using the last frame images of the dynamic 11C-acetate data", "width": 1046, "height": 416, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40], "b": [41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74]}, "subfigures": [{"id": "dd4c780e-94c8-474b-a2cf-186dce13f59f", "label": "a", "points": [[32.3, 3], [32.3, 379.8], [491.6, 379.8], [491.6, 3]], "color": "yellow"}, {"id": 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{"pdf_hash": "04250e99c8f6d3d40bb849f17e74fe104a55fdf3", "fig_key": "Figure3", "fig_uri": "4-Figure3-1.png", "text": "Fig. 3. Computed tomography (CT) images and a fundoscopic examination of Case 1. (3a) After 10 days of chemotherapy, abdominal CT revealed submucosal bleeding of the intestine and obstructive ileus in cross-sectional images. (3b) After 16 days of chemotherapy, a fundoscopic examination revealed a left submacular hemorrhage (arrow).", "width": 680, "height": 1012, "subcaptions": {"a": [18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43], "b": [44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64]}, "subfigures": [{"id": "b9c0ebb0-cf3e-4ee5-bbd4-ff9907e9d054", "label": "a", "points": [[1.4, 0.9], [1.4, 520.8], [607.2, 520.8], [607.2, 0.9]], "color": "cyan"}, {"id": "84233cdb-620b-44cd-8b89-a30f66ab03ea", "label": "b", "points": [[1.4, 543.9], [1.4, 985.4], [676, 985.4], [676, 543.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Computed", "start": 8, "end": 16, "id": 4}, {"text": "tomography", "start": 17, "end": 27, "id": 5}, {"text": "(", "start": 28, "end": 29, "id": 6}, {"text": "CT", "start": 29, "end": 31, "id": 7}, {"text": ")", "start": 31, "end": 32, "id": 8}, {"text": "images", "start": 33, "end": 39, "id": 9}, {"text": "and", "start": 40, "end": 43, "id": 10}, {"text": "a", "start": 44, "end": 45, "id": 11}, {"text": "fundoscopic", "start": 46, "end": 57, "id": 12}, {"text": "examination", "start": 58, "end": 69, "id": 13}, {"text": "of", "start": 70, "end": 72, "id": 14}, {"text": "Case", "start": 73, "end": 77, "id": 15}, {"text": "1", "start": 78, "end": 79, "id": 16}, {"text": ".", "start": 79, "end": 80, "id": 17}, {"text": "(", "start": 81, "end": 82, "id": 18}, {"text": "3a", "start": 82, "end": 84, "id": 19}, {"text": ")", "start": 84, "end": 85, "id": 20}, {"text": "After", "start": 86, "end": 91, "id": 21}, {"text": "10", "start": 92, "end": 94, "id": 22}, {"text": "days", "start": 95, "end": 99, "id": 23}, {"text": "of", "start": 100, "end": 102, "id": 24}, {"text": "chemotherapy", "start": 103, "end": 115, "id": 25}, {"text": ",", "start": 115, "end": 116, "id": 26}, {"text": "abdominal", "start": 117, "end": 126, "id": 27}, {"text": "CT", "start": 127, "end": 129, "id": 28}, {"text": "revealed", "start": 130, "end": 138, "id": 29}, {"text": "submucosal", "start": 139, "end": 149, "id": 30}, {"text": "bleeding", "start": 150, "end": 158, "id": 31}, {"text": "of", "start": 159, "end": 161, "id": 32}, {"text": "the", "start": 162, "end": 165, "id": 33}, {"text": "intestine", "start": 166, "end": 175, "id": 34}, {"text": "and", "start": 176, "end": 179, "id": 35}, {"text": "obstructive", "start": 180, "end": 191, "id": 36}, {"text": "ileus", "start": 192, "end": 197, "id": 37}, {"text": "in", "start": 198, "end": 200, "id": 38}, {"text": "cross", "start": 201, "end": 206, "id": 39}, {"text": "-", "start": 206, "end": 207, "id": 40}, {"text": "sectional", "start": 207, "end": 216, "id": 41}, {"text": "images", "start": 217, "end": 223, "id": 42}, {"text": ".", "start": 223, "end": 224, "id": 43}, {"text": "(", "start": 225, "end": 226, "id": 44}, {"text": "3b", "start": 226, "end": 228, "id": 45}, {"text": ")", "start": 228, "end": 229, "id": 46}, {"text": "After", "start": 230, "end": 235, "id": 47}, {"text": "16", "start": 236, "end": 238, "id": 48}, {"text": "days", "start": 239, "end": 243, "id": 49}, {"text": "of", "start": 244, "end": 246, "id": 50}, {"text": "chemotherapy", "start": 247, "end": 259, "id": 51}, {"text": ",", "start": 259, "end": 260, "id": 52}, {"text": "a", "start": 261, "end": 262, "id": 53}, {"text": "fundoscopic", "start": 263, "end": 274, "id": 54}, {"text": "examination", "start": 275, "end": 286, "id": 55}, {"text": "revealed", "start": 287, "end": 295, "id": 56}, {"text": "a", "start": 296, "end": 297, "id": 57}, {"text": "left", "start": 298, "end": 302, "id": 58}, {"text": "submacular", "start": 303, "end": 313, "id": 59}, {"text": "hemorrhage", "start": 314, "end": 324, "id": 60}, {"text": "(", "start": 325, "end": 326, "id": 61}, {"text": "arrow", "start": 326, "end": 331, "id": 62}, {"text": ")", "start": 331, "end": 332, "id": 63}, {"text": ".", "start": 332, "end": 333, "id": 64}]}
{"pdf_hash": "fd995867c7339e523872a267dd2e9138fedf6ce9", "fig_key": "Figure8", "fig_uri": "7-Figure8-1.png", "text": "Figure 8. Binding and uptake of FITC-labeled transferrin in control and mutant hSFs. FITC\u2013transferrin was bound to control (A and C) and DAPAT-deficient (patient 3) (B and D) cells at 0\u00b0C (A and B) and uptake was analyzed after 10 min at 37\u00b0C (C and D). Note that in control cells (C) most of the internalized transferrin is released, whereas in the mutants, as demonstrated by three-dimensional confocal imaging (insets), distinct amounts are still present at the surface and internalized transferrin accumulates in perinuclear, late endosomal/lysosomal structures (D). 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{"pdf_hash": "7ec10fd6b02ed33988cf995ce46abd7c1e799523", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3 Endoscopic full-thickness resection with the full thickness resection device. A: Endoscopic aspect of a recurrence after piecemeal endoscopic mucosal resection in the ascending colon. B: The lesion is marked and retracted into the resection cap using a grasping forceps. C: Resection bed with over the scope clip in situ. Note the periluminal fat within the clip. D: Resected specimen on corkboard. 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{"pdf_hash": "7497927c4e7056f00b8d4a60fd91df425a76150c", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Renal Manifestations of TSC. (A) CT scan of the abdomen in the year 2002, which shows large kidneys with multiple angiomyolipomas and a subcapsular haematoma (double asterisk) in the left kidney. (B) Macroscopic view of the left kidney after nephrectomy; co-existence of RCC (arrows) and angiomyolipomatous tissue.", "width": 1036, "height": 626, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41], "b": [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65]}, "subfigures": [{"id": "75f79774-f248-433c-bbec-52a706c3a9e7", "label": "a", "points": [[2.1, 30.9], [2.1, 590.6], [610.9, 590.6], [610.9, 30.9]], "color": "yellow"}, {"id": "b1593e55-737b-4978-945c-8c006610e157", "label": "b", "points": [[642, 37.4], [642, 590.6], [1005.3, 590.6], [1005.3, 37.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Renal", "start": 8, "end": 13, "id": 4}, {"text": "Manifestations", "start": 14, "end": 28, "id": 5}, {"text": "of", "start": 29, "end": 31, "id": 6}, {"text": "TSC", "start": 32, "end": 35, "id": 7}, {"text": ".", "start": 35, "end": 36, "id": 8}, {"text": "(", "start": 37, "end": 38, "id": 9}, {"text": "A", "start": 38, "end": 39, "id": 10}, {"text": ")", "start": 39, "end": 40, "id": 11}, {"text": "CT", "start": 41, "end": 43, "id": 12}, {"text": "scan", "start": 44, "end": 48, "id": 13}, {"text": "of", "start": 49, "end": 51, "id": 14}, {"text": "the", "start": 52, "end": 55, "id": 15}, {"text": "abdomen", "start": 56, "end": 63, "id": 16}, {"text": "in", "start": 64, "end": 66, "id": 17}, {"text": "the", "start": 67, "end": 70, "id": 18}, {"text": "year", "start": 71, "end": 75, "id": 19}, {"text": "2002", "start": 76, "end": 80, "id": 20}, {"text": ",", "start": 80, "end": 81, "id": 21}, {"text": "which", "start": 82, "end": 87, "id": 22}, {"text": "shows", "start": 88, "end": 93, "id": 23}, {"text": "large", "start": 94, "end": 99, "id": 24}, {"text": "kidneys", "start": 100, "end": 107, "id": 25}, {"text": "with", "start": 108, "end": 112, "id": 26}, {"text": "multiple", "start": 113, "end": 121, "id": 27}, {"text": "angiomyolipomas", "start": 122, "end": 137, "id": 28}, {"text": "and", "start": 138, "end": 141, "id": 29}, {"text": "a", "start": 142, "end": 143, "id": 30}, {"text": "subcapsular", "start": 144, "end": 155, "id": 31}, {"text": "haematoma", "start": 156, "end": 165, "id": 32}, {"text": "(", "start": 166, "end": 167, "id": 33}, {"text": "double", "start": 167, "end": 173, "id": 34}, {"text": "asterisk", "start": 174, "end": 182, "id": 35}, {"text": ")", "start": 182, "end": 183, "id": 36}, {"text": "in", "start": 184, "end": 186, "id": 37}, {"text": "the", "start": 187, "end": 190, "id": 38}, {"text": "left", "start": 191, "end": 195, "id": 39}, {"text": "kidney", "start": 196, "end": 202, "id": 40}, {"text": ".", "start": 202, "end": 203, "id": 41}, {"text": "(", "start": 204, "end": 205, "id": 42}, {"text": "B", "start": 205, "end": 206, "id": 43}, {"text": ")", "start": 206, "end": 207, "id": 44}, {"text": "Macroscopic", "start": 208, "end": 219, "id": 45}, {"text": "view", "start": 220, "end": 224, "id": 46}, {"text": "of", "start": 225, "end": 227, "id": 47}, {"text": "the", "start": 228, "end": 231, "id": 48}, {"text": "left", "start": 232, "end": 236, "id": 49}, {"text": "kidney", "start": 237, "end": 243, "id": 50}, {"text": "after", "start": 244, "end": 249, "id": 51}, {"text": "nephrectomy", "start": 250, "end": 261, "id": 52}, {"text": ";", "start": 261, "end": 262, "id": 53}, {"text": "co", "start": 263, "end": 265, "id": 54}, {"text": "-", "start": 265, "end": 266, "id": 55}, {"text": "existence", "start": 266, "end": 275, "id": 56}, {"text": "of", "start": 276, "end": 278, "id": 57}, {"text": "RCC", "start": 279, "end": 282, "id": 58}, {"text": "(", "start": 283, "end": 284, "id": 59}, {"text": "arrows", "start": 284, "end": 290, "id": 60}, {"text": ")", "start": 290, "end": 291, "id": 61}, {"text": "and", "start": 292, "end": 295, "id": 62}, {"text": "angiomyolipomatous", "start": 296, "end": 314, "id": 63}, {"text": "tissue", "start": 315, "end": 321, "id": 64}, {"text": ".", "start": 321, "end": 322, "id": 65}]}
{"pdf_hash": "b9b83d3f32ff1c0028ed165a28ca6c0e20301b2e", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 a Quadrant division of macular scan. b Quadrant division of optic disc scan", "width": 856, "height": 472, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9], "b": [10, 11, 12, 13, 14, 15, 16]}, "subfigures": [{"id": "7ac8f3f3-7b82-4a30-889b-2ea30daca92a", "label": "a", "points": [[39.2, 48.7], [39.2, 442.2], [417.9, 442.2], [417.9, 48.7]], "color": "yellow"}, {"id": "82580bc6-ad1f-450a-97d8-f31990503e5a", "label": "b", "points": [[442.2, 442.2], [442.2, 54.1], [824.9, 54.1], [824.9, 442.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Quadrant", "start": 9, "end": 17, "id": 4}, {"text": "division", "start": 18, "end": 26, "id": 5}, {"text": "of", "start": 27, "end": 29, "id": 6}, {"text": "macular", "start": 30, "end": 37, "id": 7}, {"text": "scan", "start": 38, "end": 42, "id": 8}, {"text": ".", "start": 42, "end": 43, "id": 9}, {"text": "b", "start": 44, "end": 45, "id": 10}, {"text": "Quadrant", "start": 46, "end": 54, "id": 11}, {"text": "division", "start": 55, "end": 63, "id": 12}, {"text": "of", "start": 64, "end": 66, "id": 13}, {"text": "optic", "start": 67, "end": 72, "id": 14}, {"text": "disc", "start": 73, "end": 77, "id": 15}, {"text": "scan", "start": 78, "end": 82, "id": 16}]}
{"pdf_hash": "08147141c7327cc8ca9e56a94730b9e65997ea57", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. ESD of the rectal laterally spreading tumor was performed. (A) Endoscopic findings revealed the laterally spreading tumor in the rectum. (B) Perimeter of the lesion is marked with cautery and a lifting agent (indigo carmine) is injected into the submucosa around the perimeter of the lesion. (C) Submucosa beneath the lesion was injected and then dissected in a free-hand manner using an electrosurgical knife until the specimen was completely resected. (D) ESD specimen of the lesion in the rectum. 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{"pdf_hash": "6f1773bea90ebb9241e552933c912a836af734a6", "fig_key": "Figure5", "fig_uri": "10-Figure5-1.png", "text": "FIGURE 5 | MS vs. SL beamforming source estimates in the beta (13-25 Hz) band. Axial, sagittal, and coronal views (left to right) of group (N = 12) SAM pseudo-F source estimates overlayed on the Colin template. Note that in all images right and left sides are crossed. Color bar indicates PSC degree. Cluster A reveals prefrontal deactivations in two views: the crosshairs in (A1) are on the left anterior medial prefrontal gyrus, and in (A2) on the right subgenual anterior cingulate. Cluster (B) shows deactivation in the posterior medial cortex, with the crosshairs pinpointing the right precuneus. 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{"pdf_hash": "2aa29709029928d5daa3079249cda54fd8ffc1cf", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3. Hyperpolarised 13 C imaging in the porcine brain. (A-C) Example summed [1-13 C]pyruvate, summed [1-13 C]lactate and k P maps of the porcine brain post saline infusion, respectively. Here no detectable lactate signal is observed post bolus, with [1-13 C]pyruvate appearing in the major vessels of the brain. (D-F) Representative [1-13 C]pyruvate, [1-13 C]lactate, and k P of the porcine brain post mannitol infusion, respectively. Here lactate exchange is observed globally, post infusion, with a similar distribution of [1-13 C]pyruvate signal in the major vessels as seen in (A). 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A tumor response was observed seven months after the administration of conformal radiotherapy (right). The patients\u2019 left hemiparesis was ameliorated, and the KPS improved 60 to 70 (walking with a stick 32 months after treatment). C: Gd-enhanced T1-weighted MR images. Breast cancer brain metastasis in a 70-year-old female. A large tumor in the parietal lobe (23.5 cm3) with perifocal edema was treated with a marginal dose of 35 Gy in eight fractions at an isodose of 57% (left). A tumor response was found two months after treatment, Gerstmann\u2019s syndrome disappeared, and the KPS improved 60 to 70. Marginal recurrence was noted 20 months after the first treatment, and the recurrent lesion (1.7 cm3) was treated with a marginal dose of 20 Gy at an isodose of 69% in single-session radiosurgery (center). 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{"pdf_hash": "83f42926ad026d13460065b328fad27c519f53bc", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. A, Computed tomography (CT) shows the filling of the bladder and intestine; B and C, axial CT shows the bilateral lumbar hernia.", "width": 1306, "height": 440, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30], "c": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30]}, "subfigures": [{"id": "6f944eee-0cae-4a37-9568-6a98608d4d37", "label": "a", "points": [[30, 32.7], [30, 408.2], [415.8, 408.2], [415.8, 32.7]], "color": "yellow"}, {"id": "06e501e4-076a-4197-b228-04158422ad15", "label": "b", "points": [[459.1, 28.5], [459.1, 408.2], [853.2, 408.2], [853.2, 28.5]], "color": "cyan"}, {"id": "8cabc147-78cf-4315-8570-c7409f8cfde7", "label": "c", "points": [[890.4, 26.5], [890.4, 408.2], [1280.3, 408.2], [1280.3, 26.5]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": ",", "start": 11, "end": 12, "id": 4}, {"text": "Computed", "start": 13, "end": 21, "id": 5}, {"text": "tomography", "start": 22, "end": 32, "id": 6}, {"text": "(", "start": 33, "end": 34, "id": 7}, {"text": "CT", "start": 34, "end": 36, "id": 8}, {"text": ")", "start": 36, "end": 37, "id": 9}, {"text": "shows", "start": 38, "end": 43, "id": 10}, {"text": "the", "start": 44, "end": 47, "id": 11}, {"text": "filling", "start": 48, "end": 55, "id": 12}, {"text": "of", "start": 56, "end": 58, "id": 13}, {"text": "the", "start": 59, "end": 62, "id": 14}, {"text": "bladder", "start": 63, "end": 70, "id": 15}, {"text": "and", "start": 71, "end": 74, "id": 16}, {"text": "intestine", "start": 75, "end": 84, "id": 17}, {"text": ";", "start": 84, "end": 85, "id": 18}, {"text": "B", "start": 86, "end": 87, "id": 19}, {"text": "and", "start": 88, "end": 91, "id": 20}, {"text": "C", "start": 92, "end": 93, "id": 21}, {"text": ",", "start": 93, "end": 94, "id": 22}, {"text": "axial", "start": 95, "end": 100, "id": 23}, {"text": "CT", "start": 101, "end": 103, "id": 24}, {"text": "shows", "start": 104, "end": 109, "id": 25}, {"text": "the", "start": 110, "end": 113, "id": 26}, {"text": "bilateral", "start": 114, "end": 123, "id": 27}, {"text": "lumbar", "start": 124, "end": 130, "id": 28}, {"text": "hernia", "start": 131, "end": 137, "id": 29}, {"text": ".", "start": 137, "end": 138, "id": 30}]}
{"pdf_hash": "d5825923800d0e067474cea08f1c6ab176804aa6", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Case: A 80-year-old woman. (a) Simple radiograph showed a Vancouver type B2 periprosthetic femoral fracture. (b) This patient treated by an osteosynthesis using a lateral plating and wiring. (c) Eleven months after surgery, bony union was obtained. She fell and sustained a femoral fracture at the distal end of plate, classified as Vancouver type C periprosthetic fracture. 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{"pdf_hash": "298e288968b5018043b2568713df2e8e95f911a8", "fig_key": "Figure3", "fig_uri": "9-Figure3-1.png", "text": "Fig. 3. Popliteal artery entrapment syndrome (PAES). (A) Magnetic resonance angiography of the left leg with PAES before muscle contraction. The popliteal artery has a regular blood flow. (B) Magnetic resonance angiography of the same leg after muscle contraction. The blood flow is obstructed at the level of the popliteal fossa. (C) Duplex ultrasonography of a patient with PAES before muscle contraction. (D) Duplex ultrasonography of a patient with PAES after muscle contraction. 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{"pdf_hash": "8dd18f9e98da41877645b6d10eaf811ea4028686", "fig_key": "Figure7", "fig_uri": "6-Figure7-1.png", "text": "FIG. 7. Ex vivo DTI markers of cortex and white matter abnormalities in a single brain taken 1 day following CCI were compared with fluorescence labeled immunohistochemistry. A, DTI maps for Trace and FA for the whole slice at the level of CCI injury and magnified regions of the DTI maps reveal regions of decreased Trace and FA near the CCI site compared with the uninjured side. B, A low power image of the same brain showing immunoreactivity for MAP2 and Tuj1, both neuronal markers. A decrease in staining can be seen in the same region that shows abnormalities in the DTI maps. C and D, Higher power images of the site show that both MAP2 and Tuj1 indicate reduced numbers of processes. 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{"pdf_hash": "22e5151d0c6e8a6c2d7261a10d071046d00e1a69", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Figure 3. (a) A balanced steady-state free-precession (bSSFP) MRI image of the aortic root and ascending aorta. There is a spiralling dissection flap which arises 15 mm above the sino-tubular junction and extends into the aortic arch (white arrows). The false lumen contains a large thrombus (asterisk). A jet of mild aortic regurgitation can also be observed (black arrow). (b) MR angiogram (MRA) shows the thrombus as a filling defect within the false lumen of the proximal ascending aorta (asterisk). The dissection flap in the aortic arch and proximal descending aorta is clearly seen (white arrows). 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{"pdf_hash": "df053b6236af095d10cd723b27738b4e7ec6334c", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 ICG fluorescence imaging. a Transcutaneous real-time lymphography for detection of the SLN after injection of ICG (left upper site). The lymphatic vessel (arrows) and the SLN are displayed. b The end of the lymphatic vessels with the SLN is marked on the skin for excision", "width": 646, "height": 974, "subcaptions": {"a": [7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56]}, "subfigures": [{"id": "e157d599-b9cc-4983-9ea7-d4fb0587d14b", "label": "a", "points": [[4.6, 3.9], [4.6, 485.6], [642.4, 485.6], [642.4, 3.9]], "color": "yellow"}, {"id": "c249a56a-461b-43f0-b23b-6c387d37f488", "label": "b", "points": [[1.6, 494.2], [1.6, 968.8], [642.4, 968.8], [642.4, 494.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "ICG", "start": 7, "end": 10, "id": 3}, {"text": "fluorescence", "start": 11, "end": 23, "id": 4}, {"text": "imaging", "start": 24, "end": 31, "id": 5}, {"text": ".", "start": 31, "end": 32, "id": 6}, {"text": "a", "start": 33, "end": 34, "id": 7}, {"text": "Transcutaneous", "start": 35, "end": 49, "id": 8}, {"text": "real", "start": 50, "end": 54, "id": 9}, {"text": "-", "start": 54, "end": 55, "id": 10}, {"text": "time", "start": 55, "end": 59, "id": 11}, {"text": "lymphography", "start": 60, "end": 72, "id": 12}, {"text": "for", "start": 73, "end": 76, "id": 13}, {"text": "detection", "start": 77, "end": 86, "id": 14}, {"text": "of", "start": 87, "end": 89, "id": 15}, {"text": "the", "start": 90, "end": 93, "id": 16}, {"text": "SLN", "start": 94, "end": 97, "id": 17}, {"text": "after", "start": 98, "end": 103, "id": 18}, {"text": "injection", "start": 104, "end": 113, "id": 19}, {"text": "of", "start": 114, "end": 116, "id": 20}, {"text": "ICG", "start": 117, "end": 120, "id": 21}, {"text": "(", "start": 121, "end": 122, "id": 22}, {"text": "left", "start": 122, "end": 126, "id": 23}, {"text": "upper", "start": 127, "end": 132, "id": 24}, {"text": "site", "start": 133, "end": 137, "id": 25}, {"text": ")", "start": 137, "end": 138, "id": 26}, {"text": ".", "start": 138, "end": 139, "id": 27}, {"text": "The", "start": 140, "end": 143, "id": 28}, {"text": "lymphatic", "start": 144, "end": 153, "id": 29}, {"text": "vessel", "start": 154, "end": 160, "id": 30}, {"text": "(", "start": 161, "end": 162, "id": 31}, {"text": "arrows", "start": 162, "end": 168, "id": 32}, {"text": ")", "start": 168, "end": 169, "id": 33}, {"text": "and", "start": 170, "end": 173, "id": 34}, {"text": "the", "start": 174, "end": 177, "id": 35}, {"text": "SLN", "start": 178, "end": 181, "id": 36}, {"text": "are", "start": 182, "end": 185, "id": 37}, {"text": "displayed", "start": 186, "end": 195, "id": 38}, {"text": ".", "start": 195, "end": 196, "id": 39}, {"text": "b", "start": 197, "end": 198, "id": 40}, {"text": "The", "start": 199, "end": 202, "id": 41}, {"text": "end", "start": 203, "end": 206, "id": 42}, {"text": "of", "start": 207, "end": 209, "id": 43}, {"text": "the", "start": 210, "end": 213, "id": 44}, {"text": "lymphatic", "start": 214, "end": 223, "id": 45}, {"text": "vessels", "start": 224, "end": 231, "id": 46}, {"text": "with", "start": 232, "end": 236, "id": 47}, {"text": "the", "start": 237, "end": 240, "id": 48}, {"text": "SLN", "start": 241, "end": 244, "id": 49}, {"text": "is", "start": 245, "end": 247, "id": 50}, {"text": "marked", "start": 248, "end": 254, "id": 51}, {"text": "on", "start": 255, "end": 257, "id": 52}, {"text": "the", "start": 258, "end": 261, "id": 53}, {"text": "skin", "start": 262, "end": 266, "id": 54}, {"text": "for", "start": 267, "end": 270, "id": 55}, {"text": "excision", "start": 271, "end": 279, "id": 56}]}
{"pdf_hash": "72d1075d25ac0b94a6ec00908b1dee7e47845bdf", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 A 45~ 50-year-old patient with tumor recurrence/persistence of papillary thyroid carcinoma (PTC) in a regional lymph node. Before thyroid surgery, a longitudinal gray-scale sonogram (a) showed a primary PTC in the right lobe (9.6 mm in the largest diameter). On the 44-month follow-up ultrasonography after total thyroidectomy, transverse (b) and longitudinal (c) gray-scale sonograms showed a suspicious lymph node with intranodal microcalcifications and diffusely increased echogenicity in the right lower neck (arrows, 6.6 \u00d7 8.2 \u00d7 11.0 mm). On the transverse color-Doppler sonogram (d), a suspicious lymph node showed an increased vascularity. After US-guided fine-needle aspiration for this node, nodal metastasis of PTC was diagnosed on cytology. 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{"pdf_hash": "ad0afd9640e0f5252cbb1f059aad3061c6298145", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 Sagittal and coronal MIP images (a ) of 18 F-NaF PET/CT performed because of severe back pain following the fourth cycle of chemotherapy demonstrate metastases in the thoracic vertebrae (black arrow) and sternum (white arrow). Sternum metastasis is also evident on axial PET/CT images (b ). Metastatic pulmonary lesion in the", "width": 934, "height": 500, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62]}, "subfigures": [{"id": "3a9f977e-3bb9-43c0-9522-e54b79fa4835", "label": "a", "points": [[6.3, 2.8], [6.3, 479.3], [435.7, 479.3], [435.7, 2.8]], "color": "yellow"}, {"id": "99814ea9-4fbc-49d3-8074-519e1e63518f", "label": "b", "points": [[450.4, 2.8], [450.4, 138.5], [661.4, 138.5], [661.4, 2.8]], "color": "cyan"}, {"id": "68e07bf2-f6dc-4d7e-8233-c28e49b93190", "label": "c", "points": [[450.4, 147.3], [450.4, 306.7], [657, 306.7], [657, 147.3]], "color": "magenta"}, {"id": "749dd9f8-415c-46b8-8948-d869d1875c43", "label": "d", "points": [[454.9, 315.5], [454.9, 476.4], [667.3, 476.4], [667.3, 315.5]], "color": "springgreen"}, {"id": "533758b3-ffdc-4d4c-97d4-f3f8b31dc4d5", "label": "e", "points": [[667.3, 7.2], [667.3, 235.9], [893.1, 235.9], [893.1, 7.2]], "color": "tomato"}, {"id": "c608dd4f-bfbc-46a7-8adc-3150831c93af", "label": "f", "points": [[679.1, 246.2], [679.1, 466], [896, 466], [896, 246.2]], "color": "deepskyblue"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Sagittal", "start": 7, "end": 15, "id": 3}, {"text": "and", "start": 16, "end": 19, "id": 4}, {"text": "coronal", "start": 20, "end": 27, "id": 5}, {"text": "MIP", "start": 28, "end": 31, "id": 6}, {"text": "images", "start": 32, "end": 38, "id": 7}, {"text": "(", "start": 39, "end": 40, "id": 8}, {"text": "a", "start": 40, "end": 41, "id": 9}, {"text": ")", "start": 42, "end": 43, "id": 10}, {"text": "of", "start": 44, "end": 46, "id": 11}, {"text": "18", "start": 47, "end": 49, "id": 12}, {"text": "F", "start": 50, "end": 51, "id": 13}, {"text": "-", "start": 51, "end": 52, "id": 14}, {"text": "NaF", "start": 52, "end": 55, "id": 15}, {"text": "PET", "start": 56, "end": 59, "id": 16}, {"text": "/", "start": 59, "end": 60, "id": 17}, {"text": "CT", "start": 60, "end": 62, "id": 18}, {"text": "performed", "start": 63, "end": 72, "id": 19}, {"text": "because", "start": 73, "end": 80, "id": 20}, {"text": "of", "start": 81, "end": 83, "id": 21}, {"text": "severe", "start": 84, "end": 90, "id": 22}, {"text": "back", "start": 91, "end": 95, "id": 23}, {"text": "pain", "start": 96, "end": 100, "id": 24}, {"text": "following", "start": 101, "end": 110, "id": 25}, {"text": "the", "start": 111, "end": 114, "id": 26}, {"text": "fourth", "start": 115, "end": 121, "id": 27}, {"text": "cycle", "start": 122, "end": 127, "id": 28}, {"text": "of", "start": 128, "end": 130, "id": 29}, {"text": "chemotherapy", "start": 131, "end": 143, "id": 30}, {"text": "demonstrate", "start": 144, "end": 155, "id": 31}, {"text": "metastases", "start": 156, "end": 166, "id": 32}, {"text": "in", "start": 167, "end": 169, "id": 33}, {"text": "the", "start": 170, "end": 173, "id": 34}, {"text": "thoracic", "start": 174, "end": 182, "id": 35}, {"text": "vertebrae", "start": 183, "end": 192, "id": 36}, {"text": "(", "start": 193, "end": 194, "id": 37}, {"text": "black", "start": 194, "end": 199, "id": 38}, {"text": "arrow", "start": 200, "end": 205, "id": 39}, {"text": ")", "start": 205, "end": 206, "id": 40}, {"text": "and", "start": 207, "end": 210, "id": 41}, {"text": "sternum", "start": 211, "end": 218, "id": 42}, {"text": "(", "start": 219, "end": 220, "id": 43}, {"text": "white", "start": 220, "end": 225, "id": 44}, {"text": "arrow", "start": 226, "end": 231, "id": 45}, {"text": ")", "start": 231, "end": 232, "id": 46}, {"text": ".", "start": 232, "end": 233, "id": 47}, {"text": "Sternum", "start": 234, "end": 241, "id": 48}, {"text": "metastasis", "start": 242, "end": 252, "id": 49}, {"text": "is", "start": 253, "end": 255, "id": 50}, {"text": "also", "start": 256, "end": 260, "id": 51}, {"text": "evident", "start": 261, "end": 268, "id": 52}, {"text": "on", "start": 269, "end": 271, "id": 53}, {"text": "axial", "start": 272, "end": 277, "id": 54}, {"text": "PET", "start": 278, "end": 281, "id": 55}, {"text": "/", "start": 281, "end": 282, "id": 56}, {"text": "CT", "start": 282, "end": 284, "id": 57}, {"text": "images", "start": 285, "end": 291, "id": 58}, {"text": "(", "start": 292, "end": 293, "id": 59}, {"text": "b", "start": 293, "end": 294, "id": 60}, {"text": ")", "start": 295, "end": 296, "id": 61}, {"text": ".", "start": 296, "end": 297, "id": 62}, {"text": "Metastatic", "start": 298, "end": 308, "id": 63}, {"text": "pulmonary", "start": 309, "end": 318, "id": 64}, {"text": "lesion", "start": 319, "end": 325, "id": 65}, {"text": "in", "start": 326, "end": 328, "id": 66}, {"text": "the", "start": 329, "end": 332, "id": 67}]}
{"pdf_hash": "82af2d57e812d598a38315ac7595c2332cad7283", "fig_key": "Figure1", "fig_uri": "1-Figure1-1.png", "text": "FIG. 1. MRI images of a large intruder sphere (D 25 mm) rising in a bed of smaller particles. Images are vertical cuts through the center of the container. (a) Layered bed and starting position of the intruder before shaking. (b) -(d) Size separation in the presence of convection for intruders of three different densities at \u00ff 5, f 13 Hz: (b) = m 0:08 after 23 taps; (c) = m 0:44 after 30 taps; and (d) = m 2:33 after 11 taps. Here m 1:10 g=ml is the average density of individual seeds. 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{"pdf_hash": "93937827ba03f11de55c6d8765b341bb19651717", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. CLSM images of wild-type A. thaliana roots after staining with FM4-64 (a) or after tubulin immunostaining (bf). (a) CLSM longitudinal section through the root tip, illustrating the apical root zones. (b) Cortical microtubules are predominantly transverse in interphase cells of the meristematic zone. (c) In cells that have just divided (arrow) microtubules are randomly oriented. (d) The arrow points a cell close to the quiescent center, dividing almost parallel to the root axis. (e, f) Microtubule organization in protodermal cells of the meristematic zone (marked by arrows). (e) Maximum projection of CLSM sections of the external periclinal cell face. Cortical microtubules exhibit a loose longitudinal orientation. (f) CLSM section through the inner periclinal cell face, where cortical microtubules are transverse. The root tip in these images as well as in the following ones is located towards the bottom of the page. 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{"pdf_hash": "9fc71c77c5a8317f138490e17f83bcc78e532cc6", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3 Sagittal (a) T2-weighted and transverse (b) T2-weighted at the level of mid-C2 magnetic resonance imaging scans of the cervical spine obtained 4 months after initial presentation following recurrence of clinical signs. The intramedullary lesion seen dorsal to the dens is still present (arrow), with a diffuse T2-weighted hyperintense midline intramedullary lesion seen in the dorsal cord at the level of C2 (arrowhead), suspected to represent early syrinx formation", "width": 936, "height": 292, "subcaptions": {"a": [2, 3, 4, 5, 6], "b": [8, 9, 10, 11, 12]}, "subfigures": [{"id": "71ff77e5-6e4a-41c7-b4dd-17b92d2d63fe", "label": "a", "points": [[21.5, 21.9], [21.5, 271.8], [583.4, 271.8], [583.4, 21.9]], "color": "yellow"}, {"id": "c210d20d-f442-4924-b7ab-c69ab8147569", "label": "b", "points": [[590.8, 21.9], [590.8, 276.3], [914.6, 276.3], [914.6, 21.9]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "3", "start": 7, "end": 8, "id": 1}, {"text": "Sagittal", "start": 9, "end": 17, "id": 2}, {"text": "(", "start": 18, "end": 19, "id": 3}, {"text": "a", "start": 19, "end": 20, "id": 4}, {"text": ")", "start": 20, "end": 21, "id": 5}, {"text": "T2-weighted", 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{"pdf_hash": "dcdabe37fca62469b97acbc4fa4b6cae204f912f", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3. (A) Chest X-ray taken during the second lavage procedure shows a newly developed right-side pneumothorax. (B) Chest X-ray taken after chest-tube insertion shows that the right-side pneumothorax had decreased.", "width": 1008, "height": 446, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "ec97da13-77f8-4c53-a887-1acff79f8b37", "label": "a", "points": [[7.2, 6.1], [7.2, 442.4], [408.5, 442.4], [408.5, 6.1]], "color": "yellow"}, {"id": "d63e3eb8-7c0a-48ca-b256-550468553ed6", "label": "b", "points": [[426, 7.7], [426, 439.2], [972.2, 439.2], [972.2, 7.7]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Chest", "start": 12, "end": 17, "id": 7}, {"text": "X", "start": 18, "end": 19, "id": 8}, {"text": "-", "start": 19, "end": 20, "id": 9}, {"text": "ray", "start": 20, "end": 23, "id": 10}, {"text": "taken", "start": 24, "end": 29, "id": 11}, {"text": "during", "start": 30, "end": 36, "id": 12}, {"text": "the", "start": 37, "end": 40, "id": 13}, {"text": "second", "start": 41, "end": 47, "id": 14}, {"text": "lavage", "start": 48, "end": 54, "id": 15}, {"text": "procedure", "start": 55, "end": 64, "id": 16}, {"text": "shows", "start": 65, "end": 70, "id": 17}, {"text": "a", "start": 71, "end": 72, "id": 18}, {"text": "newly", "start": 73, "end": 78, "id": 19}, {"text": "developed", "start": 79, "end": 88, "id": 20}, {"text": "right", "start": 89, "end": 94, "id": 21}, {"text": "-", "start": 94, "end": 95, "id": 22}, {"text": "side", "start": 95, "end": 99, "id": 23}, {"text": "pneumothorax", "start": 100, "end": 112, "id": 24}, {"text": ".", "start": 112, "end": 113, "id": 25}, {"text": "(", "start": 114, "end": 115, "id": 26}, {"text": "B", "start": 115, "end": 116, "id": 27}, {"text": ")", "start": 116, "end": 117, "id": 28}, {"text": "Chest", "start": 118, "end": 123, "id": 29}, {"text": "X", "start": 124, "end": 125, "id": 30}, {"text": "-", "start": 125, "end": 126, "id": 31}, {"text": "ray", "start": 126, "end": 129, "id": 32}, {"text": "taken", "start": 130, "end": 135, "id": 33}, {"text": "after", "start": 136, "end": 141, "id": 34}, {"text": "chest", "start": 142, "end": 147, "id": 35}, {"text": "-", "start": 147, "end": 148, "id": 36}, {"text": "tube", "start": 148, "end": 152, "id": 37}, {"text": "insertion", "start": 153, "end": 162, "id": 38}, {"text": "shows", "start": 163, "end": 168, "id": 39}, {"text": "that", "start": 169, "end": 173, "id": 40}, {"text": "the", "start": 174, "end": 177, "id": 41}, {"text": "right", "start": 178, "end": 183, "id": 42}, {"text": "-", "start": 183, "end": 184, "id": 43}, {"text": "side", "start": 184, "end": 188, "id": 44}, {"text": "pneumothorax", "start": 189, "end": 201, "id": 45}, {"text": "had", "start": 202, "end": 205, "id": 46}, {"text": "decreased", "start": 206, "end": 215, "id": 47}, {"text": ".", "start": 215, "end": 216, "id": 48}]}
{"pdf_hash": "7d083bb12a6533c6000ac249957826b64f925803", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "FIGURE 2. 18 F-FDG PET/CT of patient with community-acquired S. aureus bacteremia and proven endocarditis, presenting with fever, heart failure, and new cardiac murmur (aortic valve insufficiency). 18 F-FDG PET/CT detected accumulation in left common iliac artery (arrow) due to clinically silent mycotic aneurysm. This finding resulted in prolonged treatment with antibiotics and monitoring of aneurysm size. Coronal sections are shown for 18 F-FDG PET (A), CT (B), and integrated 18 F-FDG PET/CT (C).", "width": 900, "height": 234, "subcaptions": {"a": [83, 84, 85, 86, 87, 88, 89, 90], "b": [92, 93, 94, 95], "c": [98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108]}, "subfigures": [{"id": "92feb97a-011e-424f-98a9-9a9f8d99e675", "label": "a", "points": [[6.5, 5.5], [6.5, 203.1], [300.8, 203.1], [300.8, 5.5]], "color": "yellow"}, {"id": "9015aeea-5b3d-4a8d-8ee0-d98eba7c1d99", "label": "b", "points": [[305, 2.6], [305, 200.2], [595.1, 200.2], [595.1, 2.6]], "color": "cyan"}, {"id": "cf7c7eb7-0919-4766-affc-6f1f9cc724b6", "label": "c", "points": [[603.6, 2.6], [603.6, 198.8], [893.7, 198.8], [893.7, 2.6]], "color": "magenta"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "18", "start": 10, "end": 12, "id": 3}, {"text": "F", "start": 13, "end": 14, "id": 4}, {"text": "-", 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{"pdf_hash": "6b232b5041af15eb5f7f9dbb51ed4f8462e85b8c", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. Morphological characterization of a G4/ECO/pDNA N/N/P ratio 3/3/1 formulation. (a) 2D image from a tapping mode AFM scan. (b) Corresponding 3D image from the same tapping mode AFM scan. (c) TEM image of dry form G4/ECO/pDNA N/N/P ratio 3/3/1 particles.", "width": 1300, "height": 454, "subcaptions": {"a": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46], "c": [47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68]}, "subfigures": [{"id": "7f865329-0ed7-404f-bdc7-a230a9bc3a96", "label": "a", "points": [[38.1, 5.8], [38.1, 410.4], [450.9, 410.4], [450.9, 5.8]], "color": "yellow"}, {"id": "795b85d3-97ae-4a8a-8a67-3ec7997e5b71", "label": "b", "points": [[469.4, 5.8], [469.4, 416.6], [884.2, 416.6], [884.2, 5.8]], "color": "cyan"}, {"id": "5ee0d3ae-e126-4c1c-91fb-b68bda564fba", "label": "c", "points": [[898.6, 7.9], [898.6, 412.5], [1290.8, 412.5], [1290.8, 7.9]], "color": "magenta"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Morphological", "start": 10, "end": 23, "id": 3}, {"text": "characterization", "start": 24, "end": 40, "id": 4}, {"text": "of", "start": 41, "end": 43, "id": 5}, {"text": "a", "start": 44, "end": 45, "id": 6}, {"text": "G4", "start": 46, "end": 48, "id": 7}, {"text": "/", "start": 48, "end": 49, "id": 8}, {"text": "ECO", "start": 49, "end": 52, "id": 9}, {"text": "/", "start": 52, "end": 53, "id": 10}, {"text": "pDNA", "start": 53, "end": 57, "id": 11}, {"text": "N", "start": 58, "end": 59, "id": 12}, {"text": "/", "start": 59, "end": 60, "id": 13}, {"text": "N", "start": 60, "end": 61, "id": 14}, {"text": "/", "start": 61, "end": 62, "id": 15}, {"text": "P", "start": 62, "end": 63, "id": 16}, {"text": "ratio", "start": 64, "end": 69, "id": 17}, {"text": "3/3/1", "start": 70, "end": 75, "id": 18}, {"text": "formulation", "start": 76, "end": 87, "id": 19}, {"text": ".", "start": 87, "end": 88, "id": 20}, {"text": "(", "start": 89, "end": 90, "id": 21}, {"text": "a", "start": 90, "end": 91, "id": 22}, {"text": ")", "start": 91, "end": 92, "id": 23}, {"text": "2D", "start": 93, "end": 95, "id": 24}, {"text": "image", "start": 96, "end": 101, "id": 25}, {"text": "from", "start": 102, "end": 106, "id": 26}, {"text": "a", "start": 107, "end": 108, "id": 27}, {"text": "tapping", "start": 109, "end": 116, "id": 28}, {"text": "mode", "start": 117, "end": 121, "id": 29}, {"text": "AFM", "start": 122, "end": 125, "id": 30}, {"text": "scan", "start": 126, "end": 130, "id": 31}, {"text": ".", "start": 130, "end": 131, "id": 32}, {"text": "(", "start": 132, "end": 133, "id": 33}, {"text": "b", "start": 133, "end": 134, "id": 34}, {"text": ")", "start": 134, "end": 135, "id": 35}, {"text": "Corresponding", "start": 136, "end": 149, "id": 36}, {"text": "3D", "start": 150, "end": 152, "id": 37}, {"text": "image", "start": 153, "end": 158, "id": 38}, {"text": "from", "start": 159, "end": 163, "id": 39}, {"text": "the", "start": 164, "end": 167, "id": 40}, {"text": "same", "start": 168, "end": 172, "id": 41}, {"text": "tapping", "start": 173, "end": 180, "id": 42}, {"text": "mode", "start": 181, "end": 185, "id": 43}, {"text": "AFM", "start": 186, "end": 189, "id": 44}, {"text": "scan", "start": 190, "end": 194, "id": 45}, {"text": ".", "start": 194, "end": 195, "id": 46}, {"text": "(", "start": 196, "end": 197, "id": 47}, {"text": "c", "start": 197, "end": 198, "id": 48}, {"text": ")", "start": 198, "end": 199, "id": 49}, {"text": "TEM", "start": 200, "end": 203, "id": 50}, {"text": "image", "start": 204, "end": 209, "id": 51}, {"text": "of", "start": 210, "end": 212, "id": 52}, {"text": "dry", "start": 213, "end": 216, "id": 53}, {"text": "form", "start": 217, "end": 221, "id": 54}, {"text": "G4", "start": 222, "end": 224, "id": 55}, {"text": "/", "start": 224, "end": 225, "id": 56}, {"text": "ECO", "start": 225, "end": 228, "id": 57}, {"text": "/", "start": 228, "end": 229, "id": 58}, {"text": "pDNA", "start": 229, "end": 233, "id": 59}, {"text": "N", "start": 234, "end": 235, "id": 60}, {"text": "/", "start": 235, "end": 236, "id": 61}, {"text": "N", "start": 236, "end": 237, "id": 62}, {"text": "/", "start": 237, "end": 238, "id": 63}, {"text": "P", "start": 238, "end": 239, "id": 64}, {"text": "ratio", "start": 240, "end": 245, "id": 65}, {"text": "3/3/1", "start": 246, "end": 251, "id": 66}, {"text": "particles", "start": 252, "end": 261, "id": 67}, {"text": ".", "start": 261, "end": 262, "id": 68}]}
{"pdf_hash": "afcf4cfdc9d829d0910fcc5551eea8bb33f6c31f", "fig_key": "Figure2", "fig_uri": "1-Figure2-1.png", "text": "Fig. 2. (A) A transverse CT scan showing a pseudoaneurysmal formation arising from the ascending aorta and subcutaneously passing through the broken sternum. (B) A lateral CT scan showing the neck of the pseudoaneurysm below the origin of the innominate artery.", "width": 654, "height": 302, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "69ace43d-1788-4e51-80a8-63162e9f2186", "label": "a", "points": [[1.3, 1.9], [1.3, 301.5], [339.2, 301.5], [339.2, 1.9]], "color": "yellow"}, {"id": "109a5a69-2595-4133-be2c-6fd3fdcff66c", "label": "b", "points": [[343.3, 1.9], [343.3, 301.5], [650.1, 301.5], [650.1, 1.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "A", "start": 12, "end": 13, "id": 7}, {"text": "transverse", "start": 14, "end": 24, "id": 8}, {"text": "CT", "start": 25, "end": 27, "id": 9}, {"text": "scan", "start": 28, "end": 32, "id": 10}, {"text": "showing", "start": 33, "end": 40, "id": 11}, {"text": "a", "start": 41, "end": 42, "id": 12}, {"text": "pseudoaneurysmal", "start": 43, "end": 59, "id": 13}, {"text": "formation", "start": 60, "end": 69, "id": 14}, {"text": "arising", "start": 70, "end": 77, "id": 15}, {"text": "from", "start": 78, "end": 82, "id": 16}, {"text": "the", "start": 83, "end": 86, "id": 17}, {"text": "ascending", "start": 87, "end": 96, "id": 18}, {"text": "aorta", "start": 97, "end": 102, "id": 19}, {"text": "and", "start": 103, "end": 106, "id": 20}, {"text": "subcutaneously", "start": 107, "end": 121, "id": 21}, {"text": "passing", "start": 122, "end": 129, "id": 22}, {"text": "through", "start": 130, "end": 137, "id": 23}, {"text": "the", "start": 138, "end": 141, "id": 24}, {"text": "broken", "start": 142, "end": 148, "id": 25}, {"text": "sternum", "start": 149, "end": 156, "id": 26}, {"text": ".", "start": 156, "end": 157, "id": 27}, {"text": "(", "start": 158, "end": 159, "id": 28}, {"text": "B", "start": 159, "end": 160, "id": 29}, {"text": ")", "start": 160, "end": 161, "id": 30}, {"text": "A", "start": 162, "end": 163, "id": 31}, {"text": "lateral", "start": 164, "end": 171, "id": 32}, {"text": "CT", "start": 172, "end": 174, "id": 33}, {"text": "scan", "start": 175, "end": 179, "id": 34}, {"text": "showing", "start": 180, "end": 187, "id": 35}, {"text": "the", "start": 188, "end": 191, "id": 36}, {"text": "neck", "start": 192, "end": 196, "id": 37}, {"text": "of", "start": 197, "end": 199, "id": 38}, {"text": "the", "start": 200, "end": 203, "id": 39}, {"text": "pseudoaneurysm", "start": 204, "end": 218, "id": 40}, {"text": "below", "start": 219, "end": 224, "id": 41}, {"text": "the", "start": 225, "end": 228, "id": 42}, {"text": "origin", "start": 229, "end": 235, "id": 43}, {"text": "of", "start": 236, "end": 238, "id": 44}, {"text": "the", "start": 239, "end": 242, "id": 45}, {"text": "innominate", "start": 243, "end": 253, "id": 46}, {"text": "artery", "start": 254, "end": 260, "id": 47}, {"text": ".", "start": 260, "end": 261, "id": 48}]}
{"pdf_hash": "7c65803a3cd3c3d02a5ae811e60bf833bb611e8e", "fig_key": "Figure8", "fig_uri": "12-Figure8-1.png", "text": "FIGURE 8 Transverse sections of lengthened fibers . (a) A fiber with sarcomere length of 9 .4 Am . Misalignment of thick filaments is seen as isolated groups occurring in regions otherwise populated mainly by thin filaments. H, A-I, and I bands are apparent . X 40,000 . (b) Transverse section of portion of a myofibril with sarcomere length of 9 .4 \u00b5m . H, A-I, and I band regions are seen . Note occasional intrusion of thin filament into H zone . 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{"pdf_hash": "1d02e0583bd8398e1cb4c85f7545e7ed7e9681ca", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "FIGURE 1. Examples of the high-resolution computed tomography scan semi-quantitative scoring system. Each panel contains a characteristic upper and lower lobe slice of a patient scored as a) none, b) mild, c) moderate and d) severe emphysema.", "width": 1414, "height": 696, "subcaptions": {"a": [33, 34, 35], "b": [37, 38, 39], "c": [41, 42, 43], "d": [45, 46, 47]}, "subfigures": [{"id": "8c6e9ecf-0ea7-449b-8eab-b72346c58be1", "label": "a", "points": [[2.9, 1.9], [2.9, 345.9], [353.6, 345.9], [353.6, 1.9]], "color": "yellow"}, {"id": "fb796304-a711-4464-a858-b65c1a35b213", "label": "b", "points": [[364.8, 1.9], [364.8, 345.9], [695.4, 345.9], [695.4, 1.9]], "color": "magenta"}, {"id": "ab237149-9ea2-4fe1-b087-4168e0a4e722", "label": "c", "points": [[726.6, 17.6], [726.6, 339.2], [1063.9, 339.2], [1063.9, 17.6]], "color": "tomato"}, {"id": "45653046-625b-43e3-8dbb-f639c21aeea3", "label": "d", "points": [[1077.3, 8.6], [1077.3, 343.7], [1410.2, 343.7], [1410.2, 8.6]], "color": "orange"}, {"id": "19a4c8b4-51f2-4e69-8889-234f05435eed", "label": "a", "points": [[1.2, 352.3], [1.2, 690.6], [343.9, 690.6], [343.9, 352.3]], "color": "hotpink"}, {"id": "7baf2af2-7d42-4c1d-95d3-d5bd9c047fb2", "label": "b", "points": [[371.5, 352.6], [371.5, 694.4], [699.8, 694.4], [699.8, 352.6]], "color": "springgreen"}, {"id": "c2f4e88e-8e62-493f-9988-0017ca7252f2", "label": "c", "points": [[719.9, 359.3], [719.9, 692.2], [1043.8, 692.2], [1043.8, 359.3]], "color": "deepskyblue"}, {"id": "94247e14-adc3-4fc6-9d4a-ce6b808c9318", "label": "d", "points": [[1081.8, 359.3], [1081.8, 687.7], [1403.5, 687.7], [1403.5, 359.3]], "color": "hotpink"}], "tokens": [{"text": "FIGURE", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Examples", "start": 10, "end": 18, "id": 3}, {"text": "of", "start": 19, "end": 21, "id": 4}, {"text": "the", "start": 22, "end": 25, "id": 5}, {"text": "high", "start": 26, "end": 30, "id": 6}, {"text": "-", "start": 30, "end": 31, "id": 7}, {"text": "resolution", "start": 31, "end": 41, "id": 8}, {"text": "computed", "start": 42, "end": 50, "id": 9}, {"text": "tomography", "start": 51, "end": 61, "id": 10}, {"text": "scan", "start": 62, "end": 66, "id": 11}, {"text": "semi", "start": 67, "end": 71, "id": 12}, {"text": "-", "start": 71, "end": 72, "id": 13}, {"text": "quantitative", "start": 72, "end": 84, "id": 14}, {"text": "scoring", "start": 85, "end": 92, "id": 15}, {"text": "system", "start": 93, "end": 99, "id": 16}, {"text": ".", "start": 99, "end": 100, "id": 17}, {"text": "Each", "start": 101, "end": 105, "id": 18}, {"text": "panel", "start": 106, "end": 111, "id": 19}, {"text": "contains", "start": 112, "end": 120, "id": 20}, {"text": "a", "start": 121, "end": 122, "id": 21}, {"text": "characteristic", "start": 123, "end": 137, "id": 22}, {"text": "upper", "start": 138, "end": 143, "id": 23}, {"text": "and", "start": 144, "end": 147, "id": 24}, {"text": "lower", "start": 148, "end": 153, "id": 25}, {"text": "lobe", "start": 154, "end": 158, "id": 26}, {"text": "slice", "start": 159, "end": 164, "id": 27}, {"text": "of", "start": 165, "end": 167, "id": 28}, {"text": "a", "start": 168, "end": 169, "id": 29}, {"text": "patient", "start": 170, "end": 177, "id": 30}, {"text": "scored", "start": 178, "end": 184, "id": 31}, {"text": "as", "start": 185, "end": 187, "id": 32}, {"text": "a", "start": 188, "end": 189, "id": 33}, {"text": ")", "start": 189, "end": 190, "id": 34}, {"text": "none", "start": 191, "end": 195, "id": 35}, {"text": ",", "start": 195, "end": 196, "id": 36}, {"text": "b", "start": 197, "end": 198, "id": 37}, {"text": ")", "start": 198, "end": 199, "id": 38}, {"text": "mild", "start": 200, "end": 204, "id": 39}, {"text": ",", "start": 204, "end": 205, "id": 40}, {"text": "c", "start": 206, "end": 207, "id": 41}, {"text": ")", "start": 207, "end": 208, "id": 42}, {"text": "moderate", "start": 209, "end": 217, "id": 43}, {"text": "and", "start": 218, "end": 221, "id": 44}, {"text": "d", "start": 222, "end": 223, "id": 45}, {"text": ")", "start": 223, "end": 224, "id": 46}, {"text": "severe", "start": 225, "end": 231, "id": 47}, {"text": "emphysema", "start": 232, "end": 241, "id": 48}, {"text": ".", "start": 241, "end": 242, "id": 49}]}
{"pdf_hash": "f086af4770a61bf4655984e656b89afc3aeffdcf", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. Magnetic resonance imaging before liver segmentectomy: (A) sagittal plane and (B) coronal plane. A spinal tumor was detected at the level of C2 (arrow).", "width": 1002, "height": 590, "subcaptions": {"a": [10, 11, 12, 13, 14], "b": [16, 17, 18, 19, 20, 21]}, "subfigures": [{"id": "eaf57a33-d8b4-4eca-aabd-53c61d8b94db", "label": "a", "points": [[36.1, 2.9], [36.1, 555.3], [493.5, 555.3], [493.5, 2.9]], "color": "yellow"}, {"id": "e802282c-5958-4a1d-81c8-164098463e2d", "label": "b", "points": [[506.2, 1.3], [506.2, 556.9], [962, 556.9], [962, 1.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Magnetic", "start": 10, "end": 18, "id": 3}, {"text": "resonance", "start": 19, "end": 28, "id": 4}, {"text": "imaging", "start": 29, "end": 36, "id": 5}, {"text": "before", "start": 37, "end": 43, "id": 6}, {"text": "liver", "start": 44, "end": 49, "id": 7}, {"text": "segmentectomy", "start": 50, "end": 63, "id": 8}, {"text": ":", "start": 63, "end": 64, "id": 9}, {"text": "(", "start": 65, "end": 66, "id": 10}, {"text": "A", "start": 66, "end": 67, "id": 11}, {"text": ")", "start": 67, "end": 68, "id": 12}, {"text": "sagittal", "start": 69, "end": 77, "id": 13}, {"text": "plane", "start": 78, "end": 83, "id": 14}, {"text": "and", "start": 84, "end": 87, "id": 15}, {"text": "(", "start": 88, "end": 89, "id": 16}, {"text": "B", "start": 89, "end": 90, "id": 17}, {"text": ")", "start": 90, "end": 91, "id": 18}, {"text": "coronal", "start": 92, "end": 99, "id": 19}, {"text": "plane", "start": 100, "end": 105, "id": 20}, {"text": ".", "start": 105, "end": 106, "id": 21}, {"text": "A", "start": 107, "end": 108, "id": 22}, {"text": "spinal", "start": 109, "end": 115, "id": 23}, {"text": "tumor", "start": 116, "end": 121, "id": 24}, {"text": "was", "start": 122, "end": 125, "id": 25}, {"text": "detected", "start": 126, "end": 134, "id": 26}, {"text": "at", "start": 135, "end": 137, "id": 27}, {"text": "the", "start": 138, "end": 141, "id": 28}, {"text": "level", "start": 142, "end": 147, "id": 29}, {"text": "of", "start": 148, "end": 150, "id": 30}, {"text": "C2", "start": 151, "end": 153, "id": 31}, {"text": "(", "start": 154, "end": 155, "id": 32}, {"text": "arrow", "start": 155, "end": 160, "id": 33}, {"text": ")", "start": 160, "end": 161, "id": 34}, {"text": ".", "start": 161, "end": 162, "id": 35}]}
{"pdf_hash": "9c57e1fa1cc8695ab0f917dffa558604eceb023c", "fig_key": "Figure14", "fig_uri": "11-Figure14-1.png", "text": "Fig. 14 A 14-year-old boy presented with pain in the right iliac fossa of 1 month duration associated with diarrhoea. His abdomen was soft and tender at the right iliac fossa. POCUS (a) using a highfrequency linear probe of the right iliac fossa showed a thickened hyperechoic non-compressible small bowel (arrowheads). The bowel layers could not be seen. Crohn\u2019s disease was suspected. 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{"pdf_hash": "0afffe183af449900108b5634f474930a8ec7a6b", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig 2. Case 1: Preoperative and operative imaging. A, Three-dimensional reconstruction of preoperative computed tomography scan showing infradiaphragmatic dissection and previous stent in right iliac artery. B, Coronal computed tomography scan showing dissection extending up to left renal artery. C, Operative angiogram showing infradiaphragmatic dissection.", "width": 1286, "height": 568, "subcaptions": {"a": [11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "c": [48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "efd18195-aa2d-4a66-b567-a761da7e1c43", "label": "a", "points": [[30.5, 10.2], [30.5, 528.2], [430.7, 528.2], [430.7, 10.2]], "color": "yellow"}, {"id": "1aabcb76-18e2-43b4-8628-e522326842d6", "label": "b", "points": [[440.9, 532.3], [440.9, 6.1], [847.2, 6.1], [847.2, 532.3]], "color": "cyan"}, {"id": "958a1e53-b11a-4753-8ac8-1cf7d3c96038", "label": "c", "points": [[859.4, 6.1], [859.4, 526.2], [1253.5, 526.2], [1253.5, 6.1]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": "2", "start": 4, "end": 5, "id": 1}, {"text": ".", "start": 5, "end": 6, "id": 2}, {"text": "Case", "start": 7, "end": 11, "id": 3}, {"text": "1", "start": 12, "end": 13, "id": 4}, {"text": ":", "start": 13, "end": 14, "id": 5}, {"text": "Preoperative", "start": 15, "end": 27, "id": 6}, {"text": "and", "start": 28, "end": 31, "id": 7}, {"text": "operative", "start": 32, "end": 41, "id": 8}, {"text": "imaging", "start": 42, "end": 49, "id": 9}, {"text": ".", "start": 49, "end": 50, "id": 10}, {"text": "A", "start": 51, "end": 52, "id": 11}, {"text": ",", "start": 52, "end": 53, "id": 12}, {"text": "Three", "start": 54, "end": 59, "id": 13}, {"text": "-", "start": 59, "end": 60, "id": 14}, {"text": "dimensional", "start": 60, "end": 71, "id": 15}, {"text": "reconstruction", "start": 72, "end": 86, "id": 16}, {"text": "of", "start": 87, "end": 89, "id": 17}, {"text": "preoperative", "start": 90, "end": 102, "id": 18}, {"text": "computed", "start": 103, "end": 111, "id": 19}, {"text": "tomography", "start": 112, "end": 122, "id": 20}, {"text": "scan", "start": 123, "end": 127, "id": 21}, {"text": "showing", "start": 128, "end": 135, "id": 22}, {"text": "infradiaphragmatic", "start": 136, "end": 154, "id": 23}, {"text": "dissection", "start": 155, "end": 165, "id": 24}, {"text": "and", "start": 166, "end": 169, "id": 25}, {"text": "previous", "start": 170, "end": 178, "id": 26}, {"text": "stent", "start": 179, "end": 184, "id": 27}, {"text": "in", "start": 185, "end": 187, "id": 28}, {"text": "right", "start": 188, "end": 193, "id": 29}, {"text": "iliac", "start": 194, "end": 199, "id": 30}, {"text": "artery", "start": 200, "end": 206, "id": 31}, {"text": ".", "start": 206, "end": 207, "id": 32}, {"text": "B", "start": 208, "end": 209, "id": 33}, {"text": ",", "start": 209, "end": 210, "id": 34}, {"text": "Coronal", "start": 211, "end": 218, "id": 35}, {"text": "computed", "start": 219, "end": 227, "id": 36}, {"text": "tomography", "start": 228, "end": 238, "id": 37}, {"text": "scan", "start": 239, "end": 243, "id": 38}, {"text": "showing", "start": 244, "end": 251, "id": 39}, {"text": "dissection", "start": 252, "end": 262, "id": 40}, {"text": "extending", "start": 263, "end": 272, "id": 41}, {"text": "up", "start": 273, "end": 275, "id": 42}, {"text": "to", "start": 276, "end": 278, "id": 43}, {"text": "left", "start": 279, "end": 283, "id": 44}, {"text": "renal", "start": 284, "end": 289, "id": 45}, {"text": "artery", "start": 290, "end": 296, "id": 46}, {"text": ".", "start": 296, "end": 297, "id": 47}, {"text": "C", "start": 298, "end": 299, "id": 48}, {"text": ",", "start": 299, "end": 300, "id": 49}, {"text": "Operative", "start": 301, "end": 310, "id": 50}, {"text": "angiogram", "start": 311, "end": 320, "id": 51}, {"text": "showing", "start": 321, "end": 328, "id": 52}, {"text": "infradiaphragmatic", "start": 329, "end": 347, "id": 53}, {"text": "dissection", "start": 348, "end": 358, "id": 54}, {"text": ".", "start": 358, "end": 359, "id": 55}]}
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{"pdf_hash": "5fead3f5b6881bc66500292d305f7afab960901d", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. A 43 yrs Old Female Patient, CT Pelvis with Contrast, Axial and Coronal Images Showing Complex Cystic Lesion in Left Adnexa Adnexal with Peripheral Enhancement Associated with Pelvic Ascites Raising the Possilbilty of Malignancy", "width": 1114, "height": 460, "subcaptions": {"a": [15], "b": [17]}, "subfigures": [{"id": "5e6b7058-7605-4119-b82f-a5e62ec97fbb", "label": "a", "points": [[42.5, 35.8], [42.5, 440.6], [598.7, 440.6], [598.7, 35.8]], "color": "yellow"}, {"id": "30e6970b-1cad-4c31-9a0d-18326880a3dd", "label": "b", "points": [[605.7, 42.8], [605.7, 440.6], [1079.1, 440.6], [1079.1, 42.8]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "2", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "A", "start": 10, "end": 11, "id": 3}, {"text": "43", "start": 12, "end": 14, "id": 4}, {"text": "yrs", "start": 15, "end": 18, "id": 5}, {"text": "Old", "start": 19, "end": 22, "id": 6}, {"text": "Female", "start": 23, "end": 29, "id": 7}, {"text": "Patient", "start": 30, "end": 37, "id": 8}, {"text": ",", "start": 37, "end": 38, "id": 9}, {"text": "CT", "start": 39, "end": 41, "id": 10}, {"text": "Pelvis", "start": 42, "end": 48, "id": 11}, {"text": "with", "start": 49, "end": 53, "id": 12}, {"text": "Contrast", "start": 54, "end": 62, "id": 13}, {"text": ",", "start": 62, "end": 63, "id": 14}, {"text": "Axial", "start": 64, "end": 69, "id": 15}, {"text": "and", "start": 70, "end": 73, "id": 16}, {"text": "Coronal", "start": 74, "end": 81, "id": 17}, {"text": "Images", "start": 82, "end": 88, "id": 18}, {"text": "Showing", "start": 89, "end": 96, "id": 19}, {"text": "Complex", "start": 97, "end": 104, "id": 20}, {"text": "Cystic", "start": 105, "end": 111, "id": 21}, {"text": "Lesion", "start": 112, "end": 118, "id": 22}, {"text": "in", "start": 119, "end": 121, "id": 23}, {"text": "Left", "start": 122, "end": 126, "id": 24}, {"text": "Adnexa", "start": 127, "end": 133, "id": 25}, {"text": "Adnexal", "start": 134, "end": 141, "id": 26}, {"text": "with", "start": 142, "end": 146, "id": 27}, {"text": "Peripheral", "start": 147, "end": 157, "id": 28}, {"text": "Enhancement", "start": 158, "end": 169, "id": 29}, {"text": "Associated", "start": 170, "end": 180, "id": 30}, {"text": "with", "start": 181, "end": 185, "id": 31}, {"text": "Pelvic", "start": 186, "end": 192, "id": 32}, {"text": "Ascites", "start": 193, "end": 200, "id": 33}, {"text": "Raising", "start": 201, "end": 208, "id": 34}, {"text": "the", "start": 209, "end": 212, "id": 35}, {"text": "Possilbilty", "start": 213, "end": 224, "id": 36}, {"text": "of", "start": 225, "end": 227, "id": 37}, {"text": "Malignancy", "start": 228, "end": 238, "id": 38}]}
{"pdf_hash": "6f160341f0ec395293fcef3872e12118e601dc47", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Abdominal CT scan during the portal phase. (A) Pelvic mass (blue arrow). (B) Multiple hepatic lesions.", "width": 668, "height": 1246, "subcaptions": {"a": [12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "7f4f0e4a-c33c-4098-8aff-55fff267f1ba", "label": "a", "points": [[5.6, 2], [5.6, 729], [667.2, 729], [667.2, 2]], "color": "yellow"}, {"id": "a364ca1f-8dc1-4f27-ba6c-e8a5204495e6", "label": "b", "points": [[1.4, 774.9], [1.4, 1241.3], [667.2, 1241.3], [667.2, 774.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Abdominal", "start": 8, "end": 17, "id": 4}, {"text": "CT", "start": 18, "end": 20, "id": 5}, {"text": "scan", "start": 21, "end": 25, "id": 6}, {"text": "during", "start": 26, "end": 32, "id": 7}, {"text": "the", "start": 33, "end": 36, "id": 8}, {"text": "portal", "start": 37, "end": 43, "id": 9}, {"text": "phase", "start": 44, "end": 49, "id": 10}, {"text": ".", "start": 49, "end": 50, "id": 11}, {"text": "(", "start": 51, "end": 52, "id": 12}, {"text": "A", "start": 52, "end": 53, "id": 13}, {"text": ")", "start": 53, "end": 54, "id": 14}, {"text": "Pelvic", "start": 55, "end": 61, "id": 15}, {"text": "mass", "start": 62, "end": 66, "id": 16}, {"text": "(", "start": 67, "end": 68, "id": 17}, {"text": "blue", "start": 68, "end": 72, "id": 18}, {"text": "arrow", "start": 73, "end": 78, "id": 19}, {"text": ")", "start": 78, "end": 79, "id": 20}, {"text": ".", "start": 79, "end": 80, "id": 21}, {"text": "(", "start": 81, "end": 82, "id": 22}, {"text": "B", "start": 82, "end": 83, "id": 23}, {"text": ")", "start": 83, "end": 84, "id": 24}, {"text": "Multiple", "start": 85, "end": 93, "id": 25}, {"text": "hepatic", "start": 94, "end": 101, "id": 26}, {"text": "lesions", "start": 102, "end": 109, "id": 27}, {"text": ".", "start": 109, "end": 110, "id": 28}]}
{"pdf_hash": "f86d0206f93e2258ad8a445dd174b8ab3c2262c7", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 The preoperative transesophageal echocardiogram. a It showed transseptal interventricular communication with a shunting ratio of 2.4. b The defect (asterisk) located in the posterior septum close to the base of the posteromedial papillary muscle (P). A: anterior papillary muscle", "width": 652, "height": 456, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44]}, "subfigures": [{"id": "bcaa450d-4aed-4f00-8974-6ab5aa43f6f1", "label": "a", "points": [[33.5, 22.5], [33.5, 395.3], [326, 395.3], [326, 22.5]], "color": "yellow"}, {"id": "be927150-c3a5-4622-9b09-e383c7efc2fc", "label": "b", "points": [[330.1, 21.5], [330.1, 393.3], [622.7, 393.3], [622.7, 21.5]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "The", "start": 7, "end": 10, "id": 3}, {"text": "preoperative", "start": 11, "end": 23, "id": 4}, {"text": "transesophageal", "start": 24, "end": 39, "id": 5}, {"text": "echocardiogram", "start": 40, "end": 54, "id": 6}, {"text": ".", "start": 54, "end": 55, "id": 7}, {"text": "a", "start": 56, "end": 57, "id": 8}, {"text": "It", "start": 58, "end": 60, "id": 9}, {"text": "showed", "start": 61, "end": 67, "id": 10}, {"text": "transseptal", "start": 68, "end": 79, "id": 11}, {"text": "interventricular", "start": 80, "end": 96, "id": 12}, {"text": "communication", "start": 97, "end": 110, "id": 13}, {"text": "with", "start": 111, "end": 115, "id": 14}, {"text": "a", "start": 116, "end": 117, "id": 15}, {"text": "shunting", "start": 118, "end": 126, "id": 16}, {"text": "ratio", "start": 127, "end": 132, "id": 17}, {"text": "of", "start": 133, "end": 135, "id": 18}, {"text": "2.4", "start": 136, "end": 139, "id": 19}, {"text": ".", "start": 139, "end": 140, "id": 20}, {"text": "b", "start": 141, "end": 142, "id": 21}, {"text": "The", "start": 143, "end": 146, "id": 22}, {"text": "defect", "start": 147, "end": 153, "id": 23}, {"text": "(", "start": 154, "end": 155, "id": 24}, {"text": "asterisk", "start": 155, "end": 163, "id": 25}, {"text": ")", "start": 163, "end": 164, "id": 26}, {"text": "located", "start": 165, "end": 172, "id": 27}, {"text": "in", "start": 173, "end": 175, "id": 28}, {"text": "the", "start": 176, "end": 179, "id": 29}, {"text": "posterior", "start": 180, "end": 189, "id": 30}, {"text": "septum", "start": 190, "end": 196, "id": 31}, {"text": "close", "start": 197, "end": 202, "id": 32}, {"text": "to", "start": 203, "end": 205, "id": 33}, {"text": "the", "start": 206, "end": 209, "id": 34}, {"text": "base", "start": 210, "end": 214, "id": 35}, {"text": "of", "start": 215, "end": 217, "id": 36}, {"text": "the", "start": 218, "end": 221, "id": 37}, {"text": "posteromedial", "start": 222, "end": 235, "id": 38}, {"text": "papillary", "start": 236, "end": 245, "id": 39}, {"text": "muscle", "start": 246, "end": 252, "id": 40}, {"text": "(", "start": 253, "end": 254, "id": 41}, {"text": "P", "start": 254, "end": 255, "id": 42}, {"text": ")", "start": 255, "end": 256, "id": 43}, {"text": ".", "start": 256, "end": 257, "id": 44}, {"text": "A", "start": 258, "end": 259, "id": 45}, {"text": ":", "start": 259, "end": 260, "id": 46}, {"text": "anterior", "start": 261, "end": 269, "id": 47}, {"text": "papillary", "start": 270, "end": 279, "id": 48}, {"text": "muscle", "start": 280, "end": 286, "id": 49}]}
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{"pdf_hash": "d303cd36b16395d328bb4fbacdce6e28b2e51ead", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2 a Computed tomography scan of the abdomen showing two hypodense lesions of the spleen. b, c Magnetic resonance imaging of the abdomen showing the two lesions in T1 and T2 mode, respectively", "width": 1014, "height": 356, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17], "b": [32, 35, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], "c": [34, 35, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "ec3e4407-6975-41f4-ba04-5adae30d3e1b", "label": "a", "points": [[36.8, 22.4], [36.8, 328.4], [349.2, 328.4], [349.2, 22.4]], "color": "yellow"}, {"id": "c20f3d05-b050-4a95-90ec-934d8ef67b28", "label": "b", "points": [[663.2, 16], [663.2, 328.4], [354, 328.4], [354, 16]], "color": "cyan"}, {"id": "9fb9fcb6-1ae0-41e0-b261-0a69b9986d79", "label": "c", "points": [[980.4, 17.6], [980.4, 330], [666.4, 330], [666.4, 17.6]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "a", "start": 7, "end": 8, "id": 3}, {"text": "Computed", "start": 9, "end": 17, "id": 4}, {"text": "tomography", "start": 18, "end": 28, "id": 5}, {"text": "scan", "start": 29, "end": 33, "id": 6}, {"text": "of", "start": 34, "end": 36, "id": 7}, {"text": "the", "start": 37, "end": 40, "id": 8}, {"text": "abdomen", "start": 41, "end": 48, "id": 9}, {"text": "showing", "start": 49, "end": 56, "id": 10}, {"text": "two", "start": 57, "end": 60, "id": 11}, {"text": "hypodense", "start": 61, "end": 70, "id": 12}, {"text": "lesions", "start": 71, "end": 78, "id": 13}, {"text": "of", "start": 79, "end": 81, "id": 14}, {"text": "the", "start": 82, "end": 85, "id": 15}, {"text": "spleen", "start": 86, "end": 92, "id": 16}, {"text": ".", "start": 92, "end": 93, "id": 17}, {"text": "b", "start": 94, "end": 95, "id": 18}, {"text": ",", "start": 95, "end": 96, "id": 19}, {"text": "c", "start": 97, "end": 98, "id": 20}, {"text": "Magnetic", "start": 99, "end": 107, "id": 21}, {"text": "resonance", "start": 108, "end": 117, "id": 22}, {"text": "imaging", "start": 118, "end": 125, "id": 23}, {"text": "of", "start": 126, "end": 128, "id": 24}, {"text": "the", "start": 129, "end": 132, "id": 25}, {"text": "abdomen", "start": 133, "end": 140, "id": 26}, {"text": "showing", "start": 141, "end": 148, "id": 27}, {"text": "the", "start": 149, "end": 152, "id": 28}, {"text": "two", "start": 153, "end": 156, "id": 29}, {"text": "lesions", "start": 157, "end": 164, "id": 30}, {"text": "in", "start": 165, "end": 167, "id": 31}, {"text": "T1", "start": 168, "end": 170, "id": 32}, {"text": "and", "start": 171, "end": 174, "id": 33}, {"text": "T2", "start": 175, "end": 177, "id": 34}, {"text": "mode", "start": 178, "end": 182, "id": 35}, {"text": ",", "start": 182, "end": 183, "id": 36}, {"text": "respectively", "start": 184, "end": 196, "id": 37}]}
{"pdf_hash": "fcce429c4f1ddcf2bcc26e8e18899ecf219e7924", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1 A 58-year-old woman with suspected lung carcinoma and bone metastasis. a, b, d 18F-FDG PET/CT imaging (a maximum intensity projection image, b, d axial fusion images) shows uptake (SUVmax 4.6) in a lesion in the third lumbar vertebra on the right (a, b yellow arrows) which is highly suspicious of metastasis, and uptake (SUVmax 11.3) in a lung nodule in the right lower lobe (a, d white arrows). c Axial noncontrast CT image (using bone windows) shows the biopsy needle", "width": 1078, "height": 600, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95], "b": [16, 17, 18, 19, 20, 21, 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{"pdf_hash": "e7f477a22838b1457dafc19107ac1658130d1a4e", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4. Antero-posterior cervical radiograph. Left: Initial taken on May 2, 2016. Right: Follow-up taken on Sep. 28, 2016. The right head translation was reduced from 67.5 mm to 36.5 mm. Red indicates patient, green indicates normal alignment.", "width": 658, "height": 412, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31]}, "subfigures": [{"id": "5693fb92-b18e-48d5-99cb-efe2162dcb32", "label": "a", "points": [[-0.5, 4], [-0.5, 377.1], [316.5, 377.1], [316.5, 4]], "color": "yellow"}, {"id": "63a0b2b7-33c5-4a75-9dab-dd290ee2fd4c", "label": "b", "points": [[319.7, 2.9], [319.7, 377.1], [630.4, 377.1], [630.4, 2.9]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Antero", "start": 8, "end": 14, "id": 4}, {"text": "-", "start": 14, "end": 15, "id": 5}, {"text": "posterior", "start": 15, "end": 24, "id": 6}, {"text": "cervical", "start": 25, "end": 33, "id": 7}, {"text": "radiograph", "start": 34, "end": 44, "id": 8}, {"text": ".", "start": 44, "end": 45, "id": 9}, {"text": "Left", "start": 46, "end": 50, "id": 10}, {"text": ":", "start": 50, "end": 51, "id": 11}, {"text": "Initial", "start": 52, "end": 59, "id": 12}, {"text": "taken", "start": 60, "end": 65, "id": 13}, {"text": "on", "start": 66, "end": 68, "id": 14}, {"text": "May", "start": 69, "end": 72, "id": 15}, {"text": "2", "start": 73, "end": 74, "id": 16}, {"text": ",", "start": 74, "end": 75, "id": 17}, {"text": "2016", "start": 76, "end": 80, "id": 18}, {"text": ".", "start": 80, "end": 81, "id": 19}, {"text": "Right", "start": 82, "end": 87, "id": 20}, {"text": ":", "start": 87, "end": 88, "id": 21}, {"text": "Follow", "start": 89, "end": 95, "id": 22}, {"text": "-", "start": 95, "end": 96, "id": 23}, {"text": "up", "start": 96, "end": 98, "id": 24}, {"text": "taken", "start": 99, "end": 104, "id": 25}, {"text": "on", "start": 105, "end": 107, "id": 26}, {"text": "Sep.", "start": 108, "end": 112, "id": 27}, {"text": "28", "start": 113, "end": 115, "id": 28}, {"text": ",", "start": 115, "end": 116, "id": 29}, {"text": "2016", "start": 117, "end": 121, "id": 30}, {"text": ".", "start": 121, "end": 122, "id": 31}, {"text": "The", "start": 123, "end": 126, "id": 32}, {"text": "right", "start": 127, "end": 132, "id": 33}, {"text": "head", "start": 133, "end": 137, "id": 34}, {"text": "translation", "start": 138, "end": 149, "id": 35}, {"text": "was", "start": 150, "end": 153, "id": 36}, {"text": "reduced", "start": 154, "end": 161, "id": 37}, {"text": "from", "start": 162, "end": 166, "id": 38}, {"text": "67.5", "start": 167, "end": 171, "id": 39}, {"text": "mm", "start": 172, "end": 174, "id": 40}, {"text": "to", "start": 175, "end": 177, "id": 41}, {"text": "36.5", "start": 178, "end": 182, "id": 42}, {"text": "mm", "start": 183, "end": 185, "id": 43}, {"text": ".", "start": 185, "end": 186, "id": 44}, {"text": "Red", "start": 187, "end": 190, "id": 45}, {"text": "indicates", "start": 191, "end": 200, "id": 46}, {"text": "patient", "start": 201, "end": 208, "id": 47}, {"text": ",", "start": 208, "end": 209, "id": 48}, {"text": "green", "start": 210, "end": 215, "id": 49}, {"text": "indicates", "start": 216, "end": 225, "id": 50}, {"text": "normal", "start": 226, "end": 232, "id": 51}, {"text": "alignment", "start": 233, "end": 242, "id": 52}, {"text": ".", "start": 242, "end": 243, "id": 53}]}
{"pdf_hash": "71e27eb2e5fd805180cf9517fdf604138df62506", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2. Images of case 2. (A) C4-5 intervertebral disc herniation (arrow) compressing the right C5 root. (B) High signal intensity in the C5 root (arrowheads) on coronal T2 short-tau inversion recovery image.", "width": 1012, "height": 460, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26], "b": [27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "2df47af2-5576-45d2-b2e4-f72d425092c9", "label": "a", "points": [[3.7, 6.2], [3.7, 457], [483.3, 457], [483.3, 6.2]], "color": "yellow"}, {"id": "d70feca3-b110-4ea1-8bde-f79467aedd1c", "label": "b", "points": [[496, 3], [496, 457], [985.2, 457], [985.2, 3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Images", "start": 8, "end": 14, "id": 4}, {"text": "of", "start": 15, "end": 17, "id": 5}, {"text": "case", "start": 18, "end": 22, "id": 6}, {"text": "2", "start": 23, "end": 24, "id": 7}, {"text": ".", "start": 24, "end": 25, "id": 8}, {"text": "(", "start": 26, "end": 27, "id": 9}, {"text": "A", "start": 27, "end": 28, "id": 10}, {"text": ")", "start": 28, "end": 29, "id": 11}, {"text": "C4", "start": 30, "end": 32, "id": 12}, {"text": "-", "start": 32, "end": 33, "id": 13}, {"text": "5", "start": 33, "end": 34, "id": 14}, {"text": "intervertebral", "start": 35, "end": 49, "id": 15}, {"text": "disc", "start": 50, "end": 54, "id": 16}, {"text": "herniation", "start": 55, "end": 65, "id": 17}, {"text": "(", "start": 66, "end": 67, "id": 18}, {"text": "arrow", "start": 67, "end": 72, "id": 19}, {"text": ")", "start": 72, "end": 73, "id": 20}, {"text": "compressing", "start": 74, "end": 85, "id": 21}, {"text": "the", "start": 86, "end": 89, "id": 22}, {"text": "right", "start": 90, "end": 95, "id": 23}, {"text": "C5", "start": 96, "end": 98, "id": 24}, {"text": "root", "start": 99, "end": 103, "id": 25}, {"text": ".", "start": 103, "end": 104, "id": 26}, {"text": "(", "start": 105, "end": 106, "id": 27}, {"text": "B", "start": 106, "end": 107, "id": 28}, {"text": ")", "start": 107, "end": 108, "id": 29}, {"text": "High", "start": 109, "end": 113, "id": 30}, {"text": "signal", "start": 114, "end": 120, "id": 31}, {"text": "intensity", "start": 121, "end": 130, "id": 32}, {"text": "in", "start": 131, "end": 133, "id": 33}, {"text": "the", "start": 134, "end": 137, "id": 34}, {"text": "C5", "start": 138, "end": 140, "id": 35}, {"text": "root", "start": 141, "end": 145, "id": 36}, {"text": "(", "start": 146, "end": 147, "id": 37}, {"text": "arrowheads", "start": 147, "end": 157, "id": 38}, {"text": ")", "start": 157, "end": 158, "id": 39}, {"text": "on", "start": 159, "end": 161, "id": 40}, {"text": "coronal", "start": 162, "end": 169, "id": 41}, {"text": "T2", "start": 170, "end": 172, "id": 42}, {"text": "short", "start": 173, "end": 178, "id": 43}, {"text": "-", "start": 178, "end": 179, "id": 44}, {"text": "tau", "start": 179, "end": 182, "id": 45}, {"text": "inversion", "start": 183, "end": 192, "id": 46}, {"text": "recovery", "start": 193, "end": 201, "id": 47}, {"text": "image", "start": 202, "end": 207, "id": 48}, {"text": ".", "start": 207, "end": 208, "id": 49}]}
{"pdf_hash": "fde7212d2f4641830080fed53137421b7a472036", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. (A) Histopathologically, the resected lesion is a squamous cell carcinoma that overlies a leiomyoma in situ . The red arrows correspond to the lateral margins of the squamous cell carcinoma (H&E stain, \u00d712.5). (B) The esophageal leiomyoma is composed of bland spindle cells with no mitosis or nuclear atypia (H&E stain, \u00d740). (C) The entire layer of atypical epithelial cells is positive for the Ki-67 stain and demonstrates a Ki-67 labeling index of less than 1% (\u00d740). 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{"pdf_hash": "802a6d1936447c7a1d3b90bb787157f8781c7992", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Duplex scan showing the stent in the iatrogenic fistula (AVF) joining the profunda femoral artery (PFA) and common femoral vein (CFV). (B) Doppler flow evaluation at the level of fistula showing very high velocity and low resistance flow.", "width": 1048, "height": 696, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32], "b": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53]}, "subfigures": [{"id": "6a30cb6d-29fd-4f70-a428-f99ef6095da7", "label": "a", "points": [[40, 8.8], [40, 629.7], [498.6, 629.7], [498.6, 8.8]], "color": "yellow"}, {"id": "2518d2f2-7a14-4fd3-b66d-59098fb9218c", "label": "b", "points": [[511.9, 2.2], [511.9, 669.4], [1026.8, 669.4], [1026.8, 2.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "(", "start": 10, "end": 11, "id": 3}, {"text": "A", "start": 11, "end": 12, "id": 4}, {"text": ")", "start": 12, "end": 13, "id": 5}, {"text": "Duplex", "start": 14, "end": 20, "id": 6}, {"text": "scan", "start": 21, "end": 25, "id": 7}, {"text": "showing", "start": 26, "end": 33, "id": 8}, {"text": "the", "start": 34, "end": 37, "id": 9}, {"text": "stent", "start": 38, "end": 43, "id": 10}, {"text": "in", "start": 44, "end": 46, "id": 11}, {"text": "the", "start": 47, "end": 50, "id": 12}, {"text": "iatrogenic", "start": 51, "end": 61, "id": 13}, {"text": "fistula", "start": 62, "end": 69, "id": 14}, {"text": "(", "start": 70, "end": 71, "id": 15}, {"text": "AVF", "start": 71, "end": 74, "id": 16}, {"text": ")", "start": 74, "end": 75, "id": 17}, {"text": "joining", "start": 76, "end": 83, "id": 18}, {"text": "the", "start": 84, "end": 87, "id": 19}, {"text": "profunda", "start": 88, "end": 96, "id": 20}, {"text": "femoral", "start": 97, "end": 104, "id": 21}, {"text": "artery", "start": 105, "end": 111, "id": 22}, {"text": "(", "start": 112, "end": 113, "id": 23}, {"text": "PFA", "start": 113, "end": 116, "id": 24}, {"text": ")", "start": 116, "end": 117, "id": 25}, {"text": "and", "start": 118, "end": 121, "id": 26}, {"text": "common", "start": 122, "end": 128, "id": 27}, {"text": "femoral", "start": 129, "end": 136, "id": 28}, {"text": "vein", "start": 137, "end": 141, "id": 29}, {"text": "(", "start": 142, "end": 143, "id": 30}, {"text": "CFV", "start": 143, "end": 146, "id": 31}, {"text": ")", "start": 146, "end": 147, "id": 32}, {"text": ".", "start": 147, "end": 148, "id": 33}, {"text": "(", "start": 149, "end": 150, "id": 34}, {"text": "B", "start": 150, "end": 151, "id": 35}, {"text": ")", "start": 151, "end": 152, "id": 36}, {"text": "Doppler", "start": 153, "end": 160, "id": 37}, {"text": "flow", "start": 161, "end": 165, "id": 38}, {"text": "evaluation", "start": 166, "end": 176, "id": 39}, {"text": "at", "start": 177, "end": 179, "id": 40}, {"text": "the", "start": 180, "end": 183, "id": 41}, {"text": "level", "start": 184, "end": 189, "id": 42}, {"text": "of", "start": 190, "end": 192, "id": 43}, {"text": "fistula", "start": 193, "end": 200, "id": 44}, {"text": "showing", "start": 201, "end": 208, "id": 45}, {"text": "very", "start": 209, "end": 213, "id": 46}, {"text": "high", "start": 214, "end": 218, "id": 47}, {"text": "velocity", "start": 219, "end": 227, "id": 48}, {"text": "and", "start": 228, "end": 231, "id": 49}, {"text": "low", "start": 232, "end": 235, "id": 50}, {"text": "resistance", "start": 236, "end": 246, "id": 51}, {"text": "flow", "start": 247, "end": 251, "id": 52}, {"text": ".", "start": 251, "end": 252, "id": 53}]}
{"pdf_hash": "74cc37d95ddd29a971142ae5d06b8299d8790f40", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 Neck computed tomography revealed an irregular enhanced mass measuring 3\u00d74 cm in diameter at the left supra-clavicula\uff08A\uff09. Abdominal and chest computed tomography taken at the same time showed no metastases of abdominal lymph nodes or evidence of recurrence in the liver or lung\uff08B\uff09.", "width": 1104, "height": 406, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23], "b": [24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51]}, "subfigures": [{"id": "25f5ea01-760f-4e03-a5aa-bbb632e5b320", "label": "a", "points": [[-0.8, 3.2], [-0.8, 404.3], [557.3, 404.3], [557.3, 3.2]], "color": "yellow"}, {"id": "022aab7f-dd8f-47e9-a3c5-2dc949d7532b", "label": "b", "points": [[562.5, 3.2], [562.5, 402.6], [1099.6, 402.6], [1099.6, 3.2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "Neck", "start": 7, "end": 11, "id": 3}, {"text": "computed", "start": 12, "end": 20, "id": 4}, {"text": "tomography", "start": 21, "end": 31, "id": 5}, {"text": "revealed", "start": 32, "end": 40, "id": 6}, {"text": "an", "start": 41, "end": 43, "id": 7}, {"text": "irregular", "start": 44, "end": 53, "id": 8}, {"text": "enhanced", "start": 54, "end": 62, "id": 9}, {"text": "mass", "start": 63, "end": 67, "id": 10}, {"text": "measuring", "start": 68, "end": 77, "id": 11}, {"text": "3\u00d74", "start": 78, "end": 81, "id": 12}, {"text": "cm", "start": 82, "end": 84, "id": 13}, {"text": "in", "start": 85, "end": 87, "id": 14}, {"text": "diameter", "start": 88, "end": 96, "id": 15}, {"text": "at", "start": 97, "end": 99, "id": 16}, {"text": "the", "start": 100, "end": 103, "id": 17}, {"text": "left", "start": 104, "end": 108, "id": 18}, {"text": "supra", "start": 109, "end": 114, "id": 19}, {"text": "-", "start": 114, "end": 115, "id": 20}, {"text": "clavicula\uff08A", "start": 115, "end": 126, "id": 21}, {"text": "\uff09", "start": 126, "end": 127, "id": 22}, {"text": ".", "start": 127, "end": 128, "id": 23}, {"text": "Abdominal", "start": 129, "end": 138, "id": 24}, {"text": "and", "start": 139, "end": 142, "id": 25}, {"text": "chest", "start": 143, "end": 148, "id": 26}, {"text": "computed", "start": 149, "end": 157, "id": 27}, {"text": "tomography", "start": 158, "end": 168, "id": 28}, {"text": "taken", "start": 169, "end": 174, "id": 29}, {"text": "at", "start": 175, "end": 177, "id": 30}, {"text": "the", "start": 178, "end": 181, "id": 31}, {"text": "same", "start": 182, "end": 186, "id": 32}, {"text": "time", "start": 187, "end": 191, "id": 33}, {"text": "showed", "start": 192, "end": 198, "id": 34}, {"text": "no", "start": 199, "end": 201, "id": 35}, {"text": "metastases", "start": 202, "end": 212, "id": 36}, {"text": "of", "start": 213, "end": 215, "id": 37}, {"text": "abdominal", "start": 216, "end": 225, "id": 38}, {"text": "lymph", "start": 226, "end": 231, "id": 39}, {"text": "nodes", "start": 232, "end": 237, "id": 40}, {"text": "or", "start": 238, "end": 240, "id": 41}, {"text": "evidence", "start": 241, "end": 249, "id": 42}, {"text": "of", "start": 250, "end": 252, "id": 43}, {"text": "recurrence", "start": 253, "end": 263, "id": 44}, {"text": "in", "start": 264, "end": 266, "id": 45}, {"text": "the", "start": 267, "end": 270, "id": 46}, {"text": "liver", "start": 271, "end": 276, "id": 47}, {"text": "or", "start": 277, "end": 279, "id": 48}, {"text": "lung\uff08B", "start": 280, "end": 286, "id": 49}, {"text": "\uff09", "start": 286, "end": 287, "id": 50}, {"text": ".", "start": 287, "end": 288, "id": 51}]}
{"pdf_hash": "9bcfa95bd12a8ab34e83aa849495cc02df11dece", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 Results of CT and histopathological examination. A: Coronal CT image. B: Sagittal CT image. The red arrows indicate pheochromcytoma. C: H&E staining (40\u00d7) of pheochromcytoma. D: Immunohistochemical staining of thyroid sections: calcitonin (+).", "width": 982, "height": 682, "subcaptions": {"a": [10, 11, 12, 13, 14], "b": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "c": [28, 29, 30, 31, 32, 33, 34, 35, 36, 37], "d": [38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]}, "subfigures": [{"id": "2c062b3a-d124-454f-938b-93e9841adf42", "label": "a", "points": [[45.2, 2.1], [45.2, 323.2], [461, 323.2], [461, 2.1]], "color": "yellow"}, {"id": "f45c0295-3537-4ff0-8c1a-855f9a6dea37", "label": "b", "points": [[523.1, 9.8], [523.1, 323.2], [949.7, 323.2], [949.7, 9.8]], "color": "cyan"}, {"id": "b091caf9-dbfe-4eec-9825-5dffca0b8c37", "label": "c", "points": [[42.1, 369.7], [42.1, 661.4], [454.8, 661.4], [454.8, 369.7]], "color": "magenta"}, {"id": "142cac59-224c-445e-9276-f48719a4ad2e", "label": "d", "points": [[526.2, 368.2], [526.2, 659.9], [949.7, 659.9], [949.7, 368.2]], "color": "springgreen"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "Results", "start": 7, "end": 14, "id": 3}, {"text": "of", "start": 15, "end": 17, "id": 4}, {"text": "CT", "start": 18, "end": 20, "id": 5}, {"text": "and", "start": 21, "end": 24, "id": 6}, {"text": "histopathological", "start": 25, "end": 42, "id": 7}, {"text": "examination", "start": 43, "end": 54, "id": 8}, {"text": ".", "start": 54, "end": 55, "id": 9}, {"text": "A", "start": 56, "end": 57, "id": 10}, {"text": ":", "start": 57, "end": 58, "id": 11}, {"text": "Coronal", "start": 59, "end": 66, "id": 12}, {"text": "CT", "start": 67, "end": 69, "id": 13}, {"text": "image", "start": 70, "end": 75, "id": 14}, {"text": ".", "start": 75, "end": 76, "id": 15}, {"text": "B", "start": 77, "end": 78, "id": 16}, {"text": ":", "start": 78, "end": 79, "id": 17}, {"text": "Sagittal", "start": 80, "end": 88, "id": 18}, {"text": "CT", "start": 89, "end": 91, "id": 19}, {"text": "image", "start": 92, "end": 97, "id": 20}, {"text": ".", "start": 97, "end": 98, "id": 21}, {"text": "The", "start": 99, "end": 102, "id": 22}, {"text": "red", "start": 103, "end": 106, "id": 23}, {"text": "arrows", "start": 107, "end": 113, "id": 24}, {"text": "indicate", "start": 114, "end": 122, "id": 25}, {"text": "pheochromcytoma", "start": 123, "end": 138, "id": 26}, {"text": ".", "start": 138, "end": 139, "id": 27}, {"text": "C", "start": 140, "end": 141, "id": 28}, {"text": ":", "start": 141, "end": 142, "id": 29}, {"text": "H&E", "start": 143, "end": 146, "id": 30}, {"text": "staining", "start": 147, "end": 155, "id": 31}, {"text": "(", "start": 156, "end": 157, "id": 32}, {"text": "40\u00d7", "start": 157, "end": 160, "id": 33}, {"text": ")", "start": 160, "end": 161, "id": 34}, {"text": "of", "start": 162, "end": 164, "id": 35}, {"text": "pheochromcytoma", "start": 165, "end": 180, "id": 36}, {"text": ".", "start": 180, "end": 181, "id": 37}, {"text": "D", "start": 182, "end": 183, "id": 38}, {"text": ":", "start": 183, "end": 184, "id": 39}, {"text": "Immunohistochemical", "start": 185, "end": 204, "id": 40}, {"text": "staining", "start": 205, "end": 213, "id": 41}, {"text": "of", "start": 214, "end": 216, "id": 42}, {"text": "thyroid", "start": 217, "end": 224, "id": 43}, {"text": "sections", "start": 225, "end": 233, "id": 44}, {"text": ":", "start": 233, "end": 234, "id": 45}, {"text": "calcitonin", "start": 235, "end": 245, "id": 46}, {"text": "(", "start": 246, "end": 247, "id": 47}, {"text": "+", "start": 247, "end": 248, "id": 48}, {"text": ")", "start": 248, "end": 249, "id": 49}, {"text": ".", "start": 249, "end": 250, "id": 50}]}
{"pdf_hash": "a92a0d8bf97110201eb7c866ed9d18c77de68e7d", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. Chest computed tomography (A) and echocardiogram (B) revealed a large ovoid immobile mass (11\u00d76 cm2) in the pericardial space, which was attached to the posterior wall of the LA, and this was accompanied by a large quantity of pericardial effusion. Chemotherapy for six cycles was followed by chest computed topography (C) and an echocardiogram (D). 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{"pdf_hash": "c77060342e25eaa5bd965db7256ad6fd74279c9b", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2. 3D rendered views from micro-CT imaging of bee head case, brain and brain structures. (a) External head case with independently segmented structures: right eye (RE), left eye (LE) right lateral ocellus (RLO), median ocellus (MO), left lateral ocellus (LLO), right antenna (RAn), left antenna (LAn). (b) transparent head case showing brain in situ; (c) brain tissue, virtually segmented from head case; (d) transparent brain tissue showing brain structures in situ; (e) individually segmented brain structures independent of additional brain tissue showing: central body (CB), and one of the pair of lobulas (Lo), medullas (Me), antennal lobes (AL), mushroom body calyces (MBC) and mushroom body lobes (MBL). 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{"pdf_hash": "e452d30aabc79d60ce7417bb14544a283a7830d8", "fig_key": "Figure8", "fig_uri": "11-Figure8-1.png", "text": "FIGURE 8 | Immunochemical properties of contacts on pre-cerebellar neurons in the LRt. (A) A fluorescent micrograph showing a coronal section through the medulla containing pre-cerebellar neurons labeled with FG from the anterior cerebellum. Note the cells within the LRt and the inferior olivary complex (IO). (Gr, Gracile nucleus; mlf, medial longitudinal fasciculus; py, pyramid; Sp5, spinal trigeminal nucleus). (B) A single optical section showing a precerebellar neuron (green) with several CTb (red) contacts on it. The contact shown in the box (C) is immunoreactive for VGAT (C-C\") and the contact shown in box (D) is immunoreactive for VGLUT2 (D-D\"). CTb, b subunit of cholera toxin; FG, Fluorogold; VGLUT2, vesicular glutamate transporter 2; VGAT, vesicular GABA transporter. 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{"pdf_hash": "e4c0234e7750d322be678d19f1d64ca8cc681cd7", "fig_key": "Figure5", "fig_uri": "6-Figure5-1.png", "text": "Figure 5. Oblique coronal (a) T2w FS FSE and (b) PDw FSE images show an intraosseous cyst in the humeral head at the insertion of the anterior fibers of the ISP tendon in a 47-year-old patient. T2w FS FSE, T2-weighted fat-suppressed fast spin echo; PDw FSE, proton density\u2013weighted fast spin echo; ISP, infraspinatus.", "width": 1338, "height": 804, "subcaptions": {"a": [5, 6, 7, 8, 9, 10], "b": [12, 13, 14, 15, 16]}, "subfigures": [{"id": "822b560c-320d-4501-9e49-424e16950912", "label": "a", "points": [[34.2, 34.5], [34.2, 774.4], [649.3, 774.4], [649.3, 34.5]], "color": "yellow"}, {"id": "3d11dc1b-10d5-4c51-a996-0c8df82ceca8", "label": "b", "points": [[674.7, 30.3], [674.7, 774.4], [1310.9, 774.4], [1310.9, 30.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "5", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Oblique", "start": 10, "end": 17, "id": 3}, {"text": "coronal", "start": 18, "end": 25, "id": 4}, {"text": "(", "start": 26, "end": 27, "id": 5}, {"text": "a", "start": 27, "end": 28, "id": 6}, {"text": ")", "start": 28, "end": 29, "id": 7}, {"text": "T2w", "start": 30, "end": 33, "id": 8}, {"text": "FS", "start": 34, "end": 36, "id": 9}, {"text": "FSE", "start": 37, "end": 40, "id": 10}, {"text": "and", "start": 41, "end": 44, "id": 11}, {"text": "(", "start": 45, "end": 46, "id": 12}, {"text": "b", "start": 46, "end": 47, "id": 13}, {"text": ")", "start": 47, "end": 48, "id": 14}, {"text": "PDw", "start": 49, "end": 52, "id": 15}, {"text": "FSE", "start": 53, "end": 56, "id": 16}, {"text": "images", "start": 57, "end": 63, "id": 17}, {"text": "show", "start": 64, "end": 68, "id": 18}, {"text": "an", "start": 69, "end": 71, "id": 19}, {"text": "intraosseous", "start": 72, "end": 84, "id": 20}, {"text": "cyst", "start": 85, "end": 89, "id": 21}, {"text": "in", "start": 90, "end": 92, "id": 22}, {"text": "the", "start": 93, "end": 96, "id": 23}, {"text": "humeral", "start": 97, "end": 104, "id": 24}, {"text": "head", "start": 105, "end": 109, "id": 25}, {"text": "at", "start": 110, "end": 112, "id": 26}, {"text": "the", "start": 113, "end": 116, "id": 27}, {"text": "insertion", "start": 117, "end": 126, "id": 28}, {"text": "of", "start": 127, "end": 129, "id": 29}, {"text": "the", "start": 130, "end": 133, "id": 30}, {"text": "anterior", "start": 134, "end": 142, "id": 31}, {"text": "fibers", "start": 143, "end": 149, "id": 32}, {"text": "of", "start": 150, "end": 152, "id": 33}, {"text": "the", "start": 153, "end": 156, "id": 34}, {"text": "ISP", "start": 157, "end": 160, "id": 35}, {"text": "tendon", "start": 161, "end": 167, "id": 36}, {"text": "in", "start": 168, "end": 170, "id": 37}, {"text": "a", "start": 171, "end": 172, "id": 38}, {"text": "47-year", "start": 173, "end": 180, "id": 39}, {"text": "-", "start": 180, "end": 181, "id": 40}, {"text": "old", "start": 181, "end": 184, "id": 41}, {"text": "patient", "start": 185, "end": 192, "id": 42}, {"text": ".", "start": 192, "end": 193, "id": 43}, {"text": "T2w", "start": 194, "end": 197, "id": 44}, {"text": "FS", "start": 198, "end": 200, "id": 45}, {"text": "FSE", "start": 201, "end": 204, "id": 46}, {"text": ",", "start": 204, "end": 205, "id": 47}, {"text": "T2-weighted", "start": 206, "end": 217, "id": 48}, {"text": "fat", "start": 218, "end": 221, "id": 49}, {"text": "-", "start": 221, "end": 222, "id": 50}, {"text": "suppressed", "start": 222, "end": 232, "id": 51}, {"text": "fast", "start": 233, "end": 237, "id": 52}, {"text": "spin", "start": 238, "end": 242, "id": 53}, {"text": "echo", "start": 243, "end": 247, "id": 54}, {"text": ";", "start": 247, "end": 248, "id": 55}, {"text": "PDw", "start": 249, "end": 252, "id": 56}, {"text": "FSE", "start": 253, "end": 256, "id": 57}, {"text": ",", "start": 256, "end": 257, "id": 58}, {"text": "proton", "start": 258, "end": 264, "id": 59}, {"text": "density", "start": 265, "end": 272, "id": 60}, {"text": "\u2013", "start": 272, "end": 273, "id": 61}, {"text": "weighted", "start": 273, "end": 281, "id": 62}, {"text": "fast", "start": 282, "end": 286, "id": 63}, {"text": "spin", "start": 287, "end": 291, "id": 64}, {"text": "echo", "start": 292, "end": 296, "id": 65}, {"text": ";", "start": 296, "end": 297, "id": 66}, {"text": "ISP", "start": 298, "end": 301, "id": 67}, {"text": ",", "start": 301, "end": 302, "id": 68}, {"text": "infraspinatus", "start": 303, "end": 316, "id": 69}, {"text": ".", "start": 316, "end": 317, "id": 70}]}
{"pdf_hash": "a050a087cbfc20ad7b82475dccfe1c74eb1a9ecc", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig 1. The topographic features of the ENS in the jejunum, of the pig. (a) VIP-like immunoreactivity in a 25 \u00b5m paraffin section. Note ISP ganglion (ISP) with many immunoreactive neurons (arrow), intensely stained VIP-like positive nerve fibres in the inner circular muscle layer (IC). Weak reactivity is seen in the tunica mucosa (M). MP, myenteric plexus ; OL, outer longitudinal smooth muscle layer. i900. (b) HE stained, 5 \u00b5m paraffin section. Both the ESP ganglion (ESP) and its neurons (arrows) are larger than the ISP ganglion (ISP) and its neurons (arrow). The ESP is situated close to the inner circular muscle layer (IC) on the serosal side and to submucosal vascular arcades (v), close to the ISP ganglia (ISP). The tunica mucosa (M) with the lamina muscularis mucosae (L) is also seen. i840. (c) HE, 2n5 \u00b5m Historesin section. Two ISP ganglia in the submucous layer (SM) ; ganglia of the external ISP (ISPe) and internal ISP (ISPi) plexuses are located at 2 different topographic levels, and separated by a thin connective tissue layer (ct). The internal ISP is situated adjacent to the lamina muscularis mucosae (L) of the tunica mucosa (M). Neurons are marked by arrows. i4200.", "width": 1292, "height": 1260, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89], "b": [91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184], "c": [186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 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{"pdf_hash": "bdf9ccae197633eddd49f926323ad9ae0b8d0333", "fig_key": "Figure1", "fig_uri": "4-Figure1-1.png", "text": "Fig 1. HME patients have cranial base defects. (A) Sagittal plane T2 MRI sequence showing an example of a normal clivus (delineated by pink arrowheads) and normal posterior foramen magnum (cyan arrowhead) in a HME patient. (B-C) Sagittal plane T1 and T2 MRI sequences showing a very large osteochondroma-like outgrowth (red arrowheads) in a patient that is characterized by continuity with clivus cortical bone and marrow. For orientation, note that the cerebellum is the large tissue mass occupying the upper right half of the images. (D) Sagittal T2 MRI sequence from a patient displaying an irregularity in the occipital lip of the foramen magnum (purple arrowhead). 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{"pdf_hash": "3c662394919342fddaa5277155758b9787386b41", "fig_key": "Figure4", "fig_uri": "6-Figure4-1.png", "text": "FIGURE 4 | c-fos expression induced by optogenetic stimulation was localized in the anteromedial OT during the RTPP tests. (A) Images of c-fos mRNA expression in the OT coronal sections after the RTPP tests. Left panels, ipsilateral; right panels, contralateral. Scale bar: 200 \u00b5m. (B) Number of c-fos mRNA-expressing cells in the anteromedial OT. (C) Number of c-fos mRNA-expressing cells in the NAc medial shell. Data shows mean with individual data plots. ns, not significant; * * p < 0.01; * * * p < 0.001. 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{"pdf_hash": "ed89164621df2e540b772bd4585952e500e6f113", "fig_key": "Figure1", "fig_uri": "5-Figure1-1.png", "text": "Fig. 1 Case 2: a Unenhanced CT image at bone window settings shows that a lytic lesion with lattice\u2011like coarse trabeculae, interrupted cortex (arrowhead), and partial peripheral sclerosis (white arrow). b Enhanced CT image shows paraspinal mass and posterior intercostal artery (white arrow) passing through the lesion without involvement", "width": 1110, "height": 426, "subcaptions": {"a": [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "b": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]}, "subfigures": [{"id": "070f5a22-d401-4267-a867-7c4796b69bfa", "label": "a", "points": [[28.9, 22.8], [28.9, 391.1], [546.3, 391.1], [546.3, 22.8]], "color": "yellow"}, {"id": "01f7de1d-7074-40ea-b92f-e8bb3f6a7be8", "label": "b", "points": [[562, 22.8], [562, 392.8], [1074.1, 392.8], [1074.1, 22.8]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": "Case", "start": 7, "end": 11, "id": 3}, {"text": "2", "start": 12, "end": 13, "id": 4}, {"text": ":", "start": 13, "end": 14, "id": 5}, {"text": "a", "start": 15, "end": 16, "id": 6}, {"text": "Unenhanced", "start": 17, "end": 27, "id": 7}, {"text": "CT", "start": 28, "end": 30, "id": 8}, {"text": "image", "start": 31, "end": 36, "id": 9}, {"text": "at", "start": 37, "end": 39, "id": 10}, {"text": "bone", "start": 40, "end": 44, "id": 11}, {"text": "window", "start": 45, "end": 51, "id": 12}, {"text": "settings", "start": 52, "end": 60, "id": 13}, {"text": "shows", "start": 61, "end": 66, "id": 14}, {"text": "that", "start": 67, "end": 71, "id": 15}, {"text": "a", "start": 72, "end": 73, "id": 16}, {"text": "lytic", "start": 74, "end": 79, "id": 17}, {"text": "lesion", "start": 80, "end": 86, "id": 18}, {"text": "with", "start": 87, "end": 91, "id": 19}, {"text": "lattice\u2011like", "start": 92, "end": 104, "id": 20}, {"text": "coarse", "start": 105, "end": 111, "id": 21}, {"text": "trabeculae", "start": 112, "end": 122, "id": 22}, {"text": ",", "start": 122, "end": 123, "id": 23}, {"text": "interrupted", "start": 124, "end": 135, "id": 24}, {"text": "cortex", "start": 136, "end": 142, "id": 25}, {"text": "(", "start": 143, "end": 144, "id": 26}, {"text": "arrowhead", "start": 144, "end": 153, "id": 27}, {"text": ")", "start": 153, "end": 154, "id": 28}, {"text": ",", "start": 154, "end": 155, "id": 29}, {"text": "and", "start": 156, "end": 159, "id": 30}, {"text": "partial", "start": 160, "end": 167, "id": 31}, {"text": "peripheral", "start": 168, "end": 178, "id": 32}, {"text": "sclerosis", "start": 179, "end": 188, "id": 33}, {"text": "(", "start": 189, "end": 190, "id": 34}, {"text": "white", "start": 190, "end": 195, "id": 35}, {"text": "arrow", "start": 196, "end": 201, "id": 36}, {"text": ")", "start": 201, "end": 202, "id": 37}, {"text": ".", "start": 202, "end": 203, "id": 38}, {"text": "b", "start": 204, "end": 205, "id": 39}, {"text": "Enhanced", "start": 206, "end": 214, "id": 40}, {"text": "CT", "start": 215, "end": 217, "id": 41}, {"text": "image", "start": 218, "end": 223, "id": 42}, {"text": "shows", "start": 224, "end": 229, "id": 43}, {"text": "paraspinal", "start": 230, "end": 240, "id": 44}, {"text": "mass", "start": 241, "end": 245, "id": 45}, {"text": "and", "start": 246, "end": 249, "id": 46}, {"text": "posterior", "start": 250, "end": 259, "id": 47}, {"text": "intercostal", "start": 260, "end": 271, "id": 48}, {"text": "artery", "start": 272, "end": 278, "id": 49}, {"text": "(", "start": 279, "end": 280, "id": 50}, {"text": "white", "start": 280, "end": 285, "id": 51}, {"text": "arrow", "start": 286, "end": 291, "id": 52}, {"text": ")", "start": 291, "end": 292, "id": 53}, {"text": "passing", "start": 293, "end": 300, "id": 54}, {"text": "through", "start": 301, "end": 308, "id": 55}, {"text": "the", "start": 309, "end": 312, "id": 56}, {"text": "lesion", "start": 313, "end": 319, "id": 57}, {"text": "without", "start": 320, "end": 327, "id": 58}, {"text": "involvement", "start": 328, "end": 339, "id": 59}]}
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{"pdf_hash": "f434f59e1f59cc32f785aad95d14a80c3d6963a1", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1. Endoscopic findings. A) The stomach wall is pushed from inside the abdominal cavity. B) Guide wire puncture into the stomach wall. C) Insertion of sheath for the gastrostomy tube. D) PEG is performed in the standard fashion.", "width": 1430, "height": 1106, "subcaptions": {"a": [5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18], "b": [19, 20, 21, 22, 23, 24, 25, 26, 27, 28], "c": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38], "d": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "9379b9b6-3027-44dc-9d33-54e56a5a7743", "label": "a", "points": [[15.8, 0], [15.8, 530.9], [702.6, 530.9], [702.6, 0]], "color": "yellow"}, {"id": "4261f50b-d94b-4741-b3e9-cf9222fbe3fb", "label": "b", "points": [[722.9, 4.5], [722.9, 533.1], [1418.7, 533.1], [1418.7, 4.5]], "color": "cyan"}, {"id": "ef42d424-2dbe-4be0-bf5d-efc0bc4e32fa", "label": "c", "points": [[4.5, 537.7], [4.5, 1088.9], [709.4, 1088.9], [709.4, 537.7]], "color": "magenta"}, {"id": "503fed38-09b8-4164-92eb-4bab87572978", "label": "d", "points": [[731.9, 553.5], [731.9, 1079.8], [1421, 1079.8], [1421, 553.5]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Endoscopic", "start": 10, "end": 20, "id": 3}, {"text": "findings", "start": 21, "end": 29, "id": 4}, {"text": ".", "start": 29, "end": 30, "id": 5}, {"text": "A", "start": 31, "end": 32, "id": 6}, {"text": ")", "start": 32, "end": 33, "id": 7}, {"text": "The", "start": 34, "end": 37, "id": 8}, {"text": "stomach", "start": 38, "end": 45, "id": 9}, {"text": "wall", "start": 46, "end": 50, "id": 10}, {"text": "is", "start": 51, "end": 53, "id": 11}, {"text": "pushed", "start": 54, "end": 60, "id": 12}, {"text": "from", "start": 61, "end": 65, "id": 13}, {"text": "inside", "start": 66, "end": 72, "id": 14}, {"text": "the", "start": 73, "end": 76, "id": 15}, {"text": "abdominal", "start": 77, "end": 86, "id": 16}, {"text": "cavity", "start": 87, "end": 93, "id": 17}, {"text": ".", "start": 93, "end": 94, "id": 18}, {"text": "B", "start": 95, "end": 96, "id": 19}, {"text": ")", "start": 96, "end": 97, "id": 20}, {"text": "Guide", "start": 98, "end": 103, "id": 21}, {"text": "wire", "start": 104, "end": 108, "id": 22}, {"text": "puncture", "start": 109, "end": 117, "id": 23}, {"text": "into", "start": 118, "end": 122, "id": 24}, {"text": "the", "start": 123, "end": 126, "id": 25}, {"text": "stomach", "start": 127, "end": 134, "id": 26}, {"text": "wall", "start": 135, "end": 139, "id": 27}, {"text": ".", "start": 139, "end": 140, "id": 28}, {"text": "C", "start": 141, "end": 142, "id": 29}, {"text": ")", "start": 142, "end": 143, "id": 30}, {"text": "Insertion", "start": 144, "end": 153, "id": 31}, {"text": "of", "start": 154, "end": 156, "id": 32}, {"text": "sheath", "start": 157, "end": 163, "id": 33}, {"text": "for", "start": 164, "end": 167, "id": 34}, {"text": "the", "start": 168, "end": 171, "id": 35}, {"text": "gastrostomy", "start": 172, "end": 183, "id": 36}, {"text": "tube", "start": 184, "end": 188, "id": 37}, {"text": ".", "start": 188, "end": 189, "id": 38}, {"text": "D", "start": 190, "end": 191, "id": 39}, {"text": ")", "start": 191, "end": 192, "id": 40}, {"text": "PEG", "start": 193, "end": 196, "id": 41}, {"text": "is", "start": 197, "end": 199, "id": 42}, {"text": "performed", "start": 200, "end": 209, "id": 43}, {"text": "in", "start": 210, "end": 212, "id": 44}, {"text": "the", "start": 213, "end": 216, "id": 45}, {"text": "standard", "start": 217, "end": 225, "id": 46}, {"text": "fashion", "start": 226, "end": 233, "id": 47}, {"text": ".", "start": 233, "end": 234, "id": 48}]}
{"pdf_hash": "b882d9eaf162942adad4c9285199e2cb1d26aced", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Fig. 3 - Color Doppler ultrasonography of neck showing patent common carotid artery and internal jugular vein (A) and healed cervical scar (B).", "width": 1398, "height": 492, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [22, 23, 24, 25, 26, 27, 28]}, "subfigures": [{"id": "8ba86c62-5c68-41fe-a763-b05712f03489", "label": "b", "points": [[839.6, 18.4], [839.6, 460.1], [1394, 460.1], [1394, 18.4]], "color": "cyan"}, {"id": "4e909c4c-a8fa-4ac2-b8b7-d6728d5d826a", "label": "a", "points": [[7, 11.8], [7, 453.5], [824.2, 453.5], [824.2, 11.8]], "color": "yellow"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": "-", "start": 7, "end": 8, "id": 3}, {"text": "Color", "start": 9, "end": 14, "id": 4}, {"text": "Doppler", "start": 15, "end": 22, "id": 5}, {"text": "ultrasonography", "start": 23, "end": 38, "id": 6}, {"text": "of", "start": 39, "end": 41, "id": 7}, {"text": "neck", "start": 42, "end": 46, "id": 8}, {"text": "showing", "start": 47, "end": 54, "id": 9}, {"text": "patent", "start": 55, "end": 61, "id": 10}, {"text": "common", "start": 62, "end": 68, "id": 11}, {"text": "carotid", "start": 69, "end": 76, "id": 12}, {"text": "artery", "start": 77, "end": 83, "id": 13}, {"text": "and", "start": 84, "end": 87, "id": 14}, {"text": "internal", "start": 88, "end": 96, "id": 15}, {"text": "jugular", "start": 97, "end": 104, "id": 16}, {"text": "vein", "start": 105, "end": 109, "id": 17}, {"text": "(", "start": 110, "end": 111, "id": 18}, {"text": "A", "start": 111, "end": 112, "id": 19}, {"text": ")", "start": 112, "end": 113, "id": 20}, {"text": "and", "start": 114, "end": 117, "id": 21}, {"text": "healed", "start": 118, "end": 124, "id": 22}, {"text": "cervical", "start": 125, "end": 133, "id": 23}, {"text": "scar", "start": 134, "end": 138, "id": 24}, {"text": "(", "start": 139, "end": 140, "id": 25}, {"text": "B", "start": 140, "end": 141, "id": 26}, {"text": ")", "start": 141, "end": 142, "id": 27}, {"text": ".", "start": 142, "end": 143, "id": 28}]}
{"pdf_hash": "b8264a1c9096a59f1f29c58bf4ab58911f387d8e", "fig_key": "Figure4", "fig_uri": "9-Figure4-1.png", "text": "Figure 4: Curved multiplanar reformations acquired along the centerline of the coronary arteries at SASmode CT coronary angiography. (a) Angiogram obtained with scanning protocol B in 70-year-old man with a BMI of 27.3 kg/m2 shows atherosclerosis of the right coronary artery without significant stenosis. (b) Angiogram obtained with scanning protocol A in 58-year-old man with a BMI of 24.0 kg/m2 shows significant stenosis due to mixed plaque (arrow) in proximal left anterior descending artery.", "width": 784, "height": 690, "subcaptions": {"a": [20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91]}, "subfigures": [{"id": "53922fae-e2f1-4775-b1e6-25d4ac79c932", "label": "a", "points": [[131.6, 38.2], [131.6, 622.8], [428.9, 622.8], [428.9, 38.2]], "color": "yellow"}, {"id": "faf68c37-a712-49b9-b425-71afb45b9bbf", "label": "b", "points": [[441.3, 38.2], [441.3, 621.6], [729.8, 621.6], [729.8, 38.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ":", "start": 8, 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{"pdf_hash": "7e6aa5a5fa961888708ca417f3e6ab9db28bf8f0", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2: (a and b) Computed tomography (CT) revealed the cecum to be prominently enlarged. The cecum enlarged to 60 mm \u00d7 70 mm and the cecum walls exhibited hypertrophy (arrows). (c and d) The results of flourodeoxyglucose (FDG)-positron emission tomography coincided with a tumor-like shadow observed in CT and abnormal accumulation of FDG was observed. 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{"pdf_hash": "c457f549dddbc48b025bbb863aa4ce142db04384", "fig_key": "Figure2", "fig_uri": "6-Figure2-1.png", "text": "Figure 2 Histopathology of the murine ALTS1C1 brain tumors. (a) H&E stain of the coronal sections of ALTS1C1 tumor-bearing brain. Black arrows indicated the atypical multinucleic cells. Scale bar \u00bc 20 mm. (b) Low field imaging shows the tumor invasion into the adjacent brain tissues. Necrotic regions (white line) were selected and quantified by ImagePro software. Scale bar \u00bc 1 mm. IHC staining of the frozen sections of ALTS1C1 brain tumor by (c) CD31, (d) SDF-1, or (e) VEGFR-2 antibody. Scale bar \u00bc 200 mm. (f) CD31-positive MVD in tumor core and tumor infiltration islands (n \u00bc 6-12 fields per tumor of total five tumors; **Po0.01).", "width": 1374, "height": 1722, "subcaptions": {"a": [10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39], "b": [40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75], "c": [76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 102, 103, 104, 105, 106, 107, 108, 109], "d": [76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 92, 93, 94, 95, 102, 103, 104, 105, 106, 107, 108, 109], "e": [76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109], "f": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": 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{"pdf_hash": "9a73d7da863dfe3e6f63f1e3bc0528f03077f9e1", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Fig. 3 Imaging findings in Case 2. MRI at 4 days after admission showed high-intensity signal areas in the cerebellar vermis and the left cerebellar hemisphere on DWI (a, arrow), the loss of the proximal portion of the left PICA and dilatation of the adjacent distal portion on MRA (b, arrow), and a high-intensity signal area at the dilatation portion on T1-VISTA (c, arrow). 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{"pdf_hash": "c731ee7da92365c3e37d3e9aee0d1c883edeac40", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Fig. 5 MR Venography findings & CT Angiogram findings. MR Venography (right side) showed the extensive occlude lesions of IVC, both iliac veins, femoral veins, popliteal veins, anterior & posterior tibial veins and fibular veins. CT Angiogram (left side) showed normal arterial flow to both legs.", "width": 632, "height": 376, "subcaptions": {"a": [44, 45, 46, 47, 48, 49], "b": [11, 12, 13, 14, 15, 16]}, "subfigures": [{"id": "f8f1965d-dc2d-412d-9f36-7ccc1d9b2046", "label": "a", "points": [[2.7, 5.3], [2.7, 372.3], [263.7, 372.3], [263.7, 5.3]], "color": "yellow"}, {"id": "2116ef4d-44ae-4798-9f80-17639826fdef", "label": "b", "points": [[326.7, 1.3], [326.7, 374.3], [627.7, 374.3], [627.7, 1.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "5", "start": 5, "end": 6, "id": 2}, {"text": "MR", "start": 7, "end": 9, "id": 3}, {"text": "Venography", "start": 10, "end": 20, "id": 4}, {"text": "findings", "start": 21, "end": 29, "id": 5}, {"text": "&", "start": 30, "end": 31, "id": 6}, {"text": "CT", "start": 32, "end": 34, "id": 7}, {"text": "Angiogram", "start": 35, "end": 44, "id": 8}, {"text": "findings", "start": 45, "end": 53, "id": 9}, {"text": ".", "start": 53, "end": 54, "id": 10}, {"text": "MR", "start": 55, "end": 57, "id": 11}, {"text": "Venography", "start": 58, "end": 68, "id": 12}, {"text": "(", "start": 69, "end": 70, "id": 13}, {"text": "right", "start": 70, "end": 75, "id": 14}, {"text": "side", "start": 76, "end": 80, "id": 15}, {"text": ")", "start": 80, "end": 81, "id": 16}, {"text": "showed", "start": 82, "end": 88, "id": 17}, {"text": "the", "start": 89, "end": 92, "id": 18}, {"text": "extensive", "start": 93, "end": 102, "id": 19}, {"text": "occlude", "start": 103, "end": 110, "id": 20}, {"text": "lesions", "start": 111, "end": 118, "id": 21}, {"text": "of", "start": 119, "end": 121, "id": 22}, {"text": "IVC", "start": 122, "end": 125, "id": 23}, {"text": ",", "start": 125, "end": 126, "id": 24}, {"text": "both", "start": 127, "end": 131, "id": 25}, {"text": "iliac", "start": 132, "end": 137, "id": 26}, {"text": "veins", "start": 138, "end": 143, "id": 27}, {"text": ",", "start": 143, "end": 144, "id": 28}, {"text": "femoral", "start": 145, "end": 152, "id": 29}, {"text": "veins", "start": 153, "end": 158, "id": 30}, {"text": ",", "start": 158, "end": 159, "id": 31}, {"text": "popliteal", "start": 160, "end": 169, "id": 32}, {"text": "veins", "start": 170, "end": 175, "id": 33}, {"text": ",", "start": 175, "end": 176, "id": 34}, {"text": "anterior", "start": 177, "end": 185, "id": 35}, {"text": "&", "start": 186, "end": 187, "id": 36}, {"text": "posterior", "start": 188, "end": 197, "id": 37}, {"text": "tibial", "start": 198, "end": 204, "id": 38}, {"text": "veins", "start": 205, "end": 210, "id": 39}, {"text": "and", "start": 211, "end": 214, "id": 40}, {"text": "fibular", "start": 215, "end": 222, "id": 41}, {"text": "veins", "start": 223, "end": 228, "id": 42}, {"text": ".", "start": 228, "end": 229, "id": 43}, {"text": "CT", "start": 230, "end": 232, "id": 44}, {"text": "Angiogram", "start": 233, "end": 242, "id": 45}, {"text": "(", "start": 243, "end": 244, "id": 46}, {"text": "left", "start": 244, "end": 248, "id": 47}, {"text": "side", "start": 249, "end": 253, "id": 48}, {"text": ")", "start": 253, "end": 254, "id": 49}, {"text": "showed", "start": 255, "end": 261, "id": 50}, {"text": "normal", "start": 262, "end": 268, "id": 51}, {"text": "arterial", "start": 269, "end": 277, "id": 52}, {"text": "flow", "start": 278, "end": 282, "id": 53}, {"text": "to", "start": 283, "end": 285, "id": 54}, {"text": "both", "start": 286, "end": 290, "id": 55}, {"text": "legs", "start": 291, "end": 295, "id": 56}, {"text": ".", "start": 295, "end": 296, "id": 57}]}
{"pdf_hash": "8b4c3be67bb7b11f017317ff7a9fcf0dc7c97b54", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. \u2014 T1 weighted axial (A) and T2 weighted axial (B) images showing retroperiteonal lipoma isointense to fat tissue. At the level of the hip joint herniation of the lesion to sciatic foramen and compression of the left sciatic nerve is observed (arrow: right sciatic nerve). C. Fat-suppressed postcontrast T1 weighted coronal image shows signal loss of the retroperiteonal lipoma. No postcontrast enhancement is observed in the lesion.", "width": 672, "height": 762, "subcaptions": {"a": [58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83]}, "subfigures": [{"id": "0917b1d1-34ac-4f14-9a52-3d8f4e2c888a", "label": "a", "points": [[5.9, -0.2], [5.9, 724.9], [669.3, 724.9], [669.3, -0.2]], "color": "yellow"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "\u2014", "start": 8, "end": 9, "id": 4}, {"text": "T1", "start": 10, "end": 12, "id": 5}, {"text": "weighted", "start": 13, "end": 21, "id": 6}, {"text": "axial", "start": 22, "end": 27, "id": 7}, {"text": "(", "start": 28, "end": 29, "id": 8}, {"text": "A", "start": 29, "end": 30, "id": 9}, {"text": ")", "start": 30, "end": 31, "id": 10}, {"text": "and", "start": 32, "end": 35, "id": 11}, {"text": "T2", "start": 36, "end": 38, "id": 12}, {"text": "weighted", "start": 39, "end": 47, "id": 13}, {"text": "axial", "start": 48, "end": 53, "id": 14}, {"text": "(", "start": 54, "end": 55, "id": 15}, {"text": "B", "start": 55, "end": 56, "id": 16}, {"text": ")", "start": 56, "end": 57, "id": 17}, {"text": "images", "start": 58, "end": 64, "id": 18}, {"text": "showing", "start": 65, "end": 72, "id": 19}, {"text": "retroperiteonal", "start": 73, "end": 88, "id": 20}, {"text": "lipoma", "start": 89, "end": 95, "id": 21}, {"text": "isointense", "start": 96, "end": 106, "id": 22}, {"text": "to", "start": 107, "end": 109, "id": 23}, {"text": "fat", "start": 110, "end": 113, "id": 24}, {"text": "tissue", "start": 114, "end": 120, "id": 25}, {"text": ".", "start": 120, "end": 121, "id": 26}, {"text": "At", "start": 122, "end": 124, "id": 27}, {"text": "the", "start": 125, "end": 128, "id": 28}, {"text": "level", "start": 129, "end": 134, "id": 29}, {"text": "of", "start": 135, "end": 137, "id": 30}, {"text": "the", "start": 138, "end": 141, "id": 31}, {"text": "hip", "start": 142, "end": 145, "id": 32}, {"text": "joint", "start": 146, "end": 151, "id": 33}, {"text": "herniation", "start": 152, "end": 162, "id": 34}, {"text": "of", "start": 163, "end": 165, "id": 35}, {"text": "the", "start": 166, "end": 169, "id": 36}, {"text": "lesion", "start": 170, "end": 176, "id": 37}, {"text": "to", "start": 177, "end": 179, "id": 38}, {"text": "sciatic", "start": 180, "end": 187, "id": 39}, {"text": "foramen", "start": 188, "end": 195, "id": 40}, {"text": "and", "start": 196, "end": 199, "id": 41}, {"text": "compression", "start": 200, "end": 211, "id": 42}, {"text": "of", "start": 212, "end": 214, "id": 43}, {"text": "the", "start": 215, "end": 218, "id": 44}, {"text": "left", "start": 219, "end": 223, "id": 45}, {"text": "sciatic", "start": 224, "end": 231, "id": 46}, {"text": "nerve", "start": 232, "end": 237, "id": 47}, {"text": "is", "start": 238, "end": 240, "id": 48}, {"text": "observed", "start": 241, "end": 249, "id": 49}, {"text": "(", "start": 250, "end": 251, "id": 50}, {"text": "arrow", "start": 251, "end": 256, "id": 51}, {"text": ":", "start": 256, "end": 257, "id": 52}, {"text": "right", "start": 258, "end": 263, "id": 53}, {"text": "sciatic", "start": 264, "end": 271, "id": 54}, {"text": "nerve", "start": 272, "end": 277, "id": 55}, {"text": ")", "start": 277, "end": 278, "id": 56}, {"text": ".", "start": 278, "end": 279, "id": 57}, {"text": "C.", "start": 280, "end": 282, "id": 58}, {"text": "Fat", "start": 283, "end": 286, "id": 59}, {"text": "-", "start": 286, "end": 287, "id": 60}, {"text": "suppressed", "start": 287, "end": 297, "id": 61}, {"text": "postcontrast", "start": 298, "end": 310, "id": 62}, {"text": "T1", "start": 311, "end": 313, "id": 63}, {"text": "weighted", "start": 314, "end": 322, "id": 64}, {"text": "coronal", "start": 323, "end": 330, "id": 65}, {"text": "image", "start": 331, "end": 336, "id": 66}, {"text": "shows", "start": 337, "end": 342, "id": 67}, {"text": "signal", "start": 343, "end": 349, "id": 68}, {"text": "loss", "start": 350, "end": 354, "id": 69}, {"text": "of", "start": 355, "end": 357, "id": 70}, {"text": "the", "start": 358, "end": 361, "id": 71}, {"text": "retroperiteonal", "start": 362, "end": 377, "id": 72}, {"text": "lipoma", "start": 378, "end": 384, "id": 73}, {"text": ".", "start": 384, "end": 385, "id": 74}, {"text": "No", "start": 386, "end": 388, "id": 75}, {"text": "postcontrast", "start": 389, "end": 401, "id": 76}, {"text": "enhancement", "start": 402, "end": 413, "id": 77}, {"text": "is", "start": 414, "end": 416, "id": 78}, {"text": "observed", "start": 417, "end": 425, "id": 79}, {"text": "in", "start": 426, "end": 428, "id": 80}, {"text": "the", "start": 429, "end": 432, "id": 81}, {"text": "lesion", "start": 433, "end": 439, "id": 82}, {"text": ".", "start": 439, "end": 440, "id": 83}]}
{"pdf_hash": "7e64dbeaeb00ff27e7e678fad2c9a4c402ad0099", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Fig. 4. Immunoreactivity results for cytochrome c (A-C), M30 (D-F), and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) (G-I) in all experimental groups. (A) Very intense cytoplasmic immunolabeling in convoluted tubules in Group 1 (Ringer's lactate). (B) Very intense cytoplasmic immunolabeling in convoluted tubules in Group 2 (hydroxyethyl starch 130/0.4). (C) Moderate cytoplasmic immunolabeling in convoluted tubules in Group 3 (control). (D) Moderate immunolabeling in proximal convoluted tubules in Group 1. (E) Intense immunolabeling in collecting tubules in Group 2. (F) Absence of immunolabeling in collecting tubules in Group 3. (G) Weak immunostaining in convoluted tubules in Group 1. (H) Intense nuclear immunostaining in convoluted tubules in Group 2. (I) Negative immunostaining in Group 3. H&E stain (A-I). 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Capillaries and mesenchymal tissues (asterisks) were not stained (no counterstain; original magnification, 2303).", "width": 648, "height": 1112, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75], "b": [3, 4, 5, 6, 7, 8, 9, 10, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120]}, "subfigures": [{"id": "0c02c918-57ce-4793-b05a-988a88784d10", "label": "a", "points": [[0.6, 0.9], [0.6, 535.2], [644.4, 535.2], [644.4, 0.9]], "color": "yellow"}, {"id": "cb0125f1-99f2-45de-a8e0-d7b3a1bfa0dc", "label": "b", "points": [[1.6, 555.7], [1.6, 1080.8], [645.4, 1080.8], [645.4, 555.7]], "color": 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{"pdf_hash": "5c0cd99bbf9c962fa2b229e5a7ee9bee8b00df4a", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3 Brain MRI images and measurement of anatomical angles. One patient is shown in A\u2013C and a second patient is shown in D\u2013F. Midbrain-pons angles are shown in (B) and (E), which was defined as the angle between the line tangential to the anterior margin of the midbrain and the line tangential to the superior margin of pons based on the midline sagittal view of brain MRI; note the more severe diencephalicmesencephalic deformity with a \u2018closed\u2019 midbrain-pons angle in the second patient (E). 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{"pdf_hash": "10d8ad0d814f4bdaeaa77f3c539736d3a75876a6", "fig_key": "Figure4", "fig_uri": "3-Figure4-1.png", "text": "Fig. 4. A: Sagittal T 1 -weighted MR image of the lumbar spine obtained in September 2001, revealing an isointense mass in the L5-S1 region (white arrowheads). B: Sagittal T 2 -weighted MR image of the lumbar spine demonstrating a high-intensity circumscribed mass in the L-5 region (black arrowheads). C: Illustration of the operative findings. 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{"pdf_hash": "42630cbcc167c88f7c826318ae02f6709372f06f", "fig_key": "Figure7", "fig_uri": "9-Figure7-1.png", "text": "Figure 7. Delayed enhancement magnetic resonance imaging. 4- chamber and short axis views of De-CMR showing delayed enhancement of the free right ventricular wall. notes: The arrow indicates the area of delayed enhancement, which represents fibrofatty replacement. The figure on the right shows a significantly dilated Rv.", "width": 632, "height": 322, "subcaptions": {"a": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44], "b": [45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55]}, "subfigures": [{"id": "58078bd7-0f01-4b7b-9657-fe5b0923bbbe", "label": "a", "points": [[4, 0], [4, 321], [313, 321], [313, 0]], "color": "yellow"}, {"id": "b5f5635c-ed7e-422c-8e18-61dbc7c70a55", "label": "b", "points": [[318, 3], [318, 318], [630, 318], [630, 3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "7", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Delayed", "start": 10, "end": 17, "id": 3}, {"text": "enhancement", "start": 18, "end": 29, "id": 4}, {"text": "magnetic", "start": 30, "end": 38, "id": 5}, {"text": "resonance", "start": 39, "end": 48, "id": 6}, {"text": "imaging", "start": 49, "end": 56, "id": 7}, {"text": ".", "start": 56, "end": 57, "id": 8}, {"text": "4-", "start": 58, "end": 60, "id": 9}, {"text": "chamber", "start": 61, "end": 68, "id": 10}, {"text": "and", "start": 69, "end": 72, "id": 11}, {"text": "short", "start": 73, "end": 78, "id": 12}, {"text": "axis", "start": 79, "end": 83, "id": 13}, {"text": "views", "start": 84, "end": 89, "id": 14}, {"text": "of", "start": 90, "end": 92, "id": 15}, {"text": "De", "start": 93, "end": 95, "id": 16}, {"text": "-", "start": 95, "end": 96, "id": 17}, {"text": "CMR", "start": 96, "end": 99, "id": 18}, {"text": "showing", "start": 100, "end": 107, "id": 19}, {"text": "delayed", "start": 108, "end": 115, "id": 20}, {"text": "enhancement", "start": 116, "end": 127, "id": 21}, {"text": "of", "start": 128, "end": 130, "id": 22}, {"text": "the", "start": 131, "end": 134, "id": 23}, {"text": "free", "start": 135, "end": 139, "id": 24}, {"text": "right", "start": 140, "end": 145, "id": 25}, {"text": "ventricular", "start": 146, "end": 157, "id": 26}, {"text": "wall", "start": 158, "end": 162, "id": 27}, {"text": ".", "start": 162, "end": 163, "id": 28}, {"text": "notes", "start": 164, "end": 169, "id": 29}, {"text": ":", "start": 169, "end": 170, "id": 30}, {"text": "The", "start": 171, "end": 174, "id": 31}, {"text": "arrow", "start": 175, "end": 180, "id": 32}, {"text": "indicates", "start": 181, "end": 190, "id": 33}, {"text": "the", "start": 191, "end": 194, "id": 34}, {"text": "area", "start": 195, "end": 199, "id": 35}, {"text": "of", "start": 200, "end": 202, "id": 36}, {"text": "delayed", "start": 203, "end": 210, "id": 37}, {"text": "enhancement", "start": 211, "end": 222, "id": 38}, {"text": ",", "start": 222, "end": 223, "id": 39}, {"text": "which", "start": 224, "end": 229, "id": 40}, {"text": "represents", "start": 230, "end": 240, "id": 41}, {"text": "fibrofatty", "start": 241, "end": 251, "id": 42}, {"text": "replacement", "start": 252, "end": 263, "id": 43}, {"text": ".", "start": 263, "end": 264, "id": 44}, {"text": "The", "start": 265, "end": 268, "id": 45}, {"text": "figure", "start": 269, "end": 275, "id": 46}, {"text": "on", "start": 276, "end": 278, "id": 47}, {"text": "the", "start": 279, "end": 282, "id": 48}, {"text": "right", "start": 283, "end": 288, "id": 49}, {"text": "shows", "start": 289, "end": 294, "id": 50}, {"text": "a", "start": 295, "end": 296, "id": 51}, {"text": "significantly", "start": 297, "end": 310, "id": 52}, {"text": "dilated", "start": 311, "end": 318, "id": 53}, {"text": "Rv", "start": 319, "end": 321, "id": 54}, {"text": ".", "start": 321, "end": 322, "id": 55}]}
{"pdf_hash": "5ab2eaa224c8346a5a9a861ceb48b9d4ac890548", "fig_key": "Figure7", "fig_uri": "6-Figure7-1.png", "text": "Fig. 7. TUNEL labeling of the sling. Coronal cryostat sections at 10 \u00b5m were labeled using TUNEL and an FITC secondary antibody. TUNEL-positive cells were present within the sling at E17 and E18 (arrows in A and B respectively) but no TUNEL-positive cells were present at P0 (C) or P3 (D), despite the continuing generation of the sling cells at these ages (see Fig. 3). Even at P5 (E) and P10 (F) when the sling structure disappears there is no TUNEL labeling. 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{"pdf_hash": "bf13bc0ee8bf634aaf1abb977f182ebaddcd0107", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Figure 4. A: An injection of Alexa Fluor 488 dextran in NL at about the middle level along the medial-lateral axis. The tracer distributed throughout the dorsal (rostral) to the ventral (caudal) part of NL at this level. The asterisk marks the approximate injection center. The injection site involved the axons of NM. Retrograde labeling of cell bodies in NM is shown. B: A bright field counterpart of panel A shows the localization of NL and NM. The NM border is indicated by arrowheads. 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{"pdf_hash": "d211ce760ae8e18fb68a5881fba897562492b48a", "fig_key": "Figure4", "fig_uri": "8-Figure4-1.png", "text": "Figure 4. Ictal and interictal cerebellar metabolism in patient 19 with ATP1A2 mutation. Compared with interictal PET (low panels), ictal images (upper panels) show significant hypometabolism in bilateral cerebellar hemispheres.", "width": 1264, "height": 644, "subcaptions": {"a": [24, 25, 26, 27, 28, 29], "b": [17, 18, 19, 20, 21, 22]}, "subfigures": [{"id": "1d48641d-f14e-44a0-a2d8-c69fa919fd94", "label": "a", "points": [[16.3, 4.7], [16.3, 296.2], [1262.4, 296.2], [1262.4, 4.7]], "color": "yellow"}, {"id": "6c820c89-8f76-490c-9ade-59c13baa319c", "label": "b", "points": [[26.3, 304.2], [26.3, 623.7], [1254.4, 623.7], [1254.4, 304.2]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "4", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Ictal", "start": 10, "end": 15, "id": 3}, {"text": "and", "start": 16, "end": 19, "id": 4}, {"text": "interictal", "start": 20, "end": 30, "id": 5}, {"text": "cerebellar", "start": 31, "end": 41, "id": 6}, {"text": "metabolism", "start": 42, "end": 52, "id": 7}, {"text": "in", "start": 53, "end": 55, "id": 8}, {"text": "patient", "start": 56, "end": 63, "id": 9}, {"text": "19", "start": 64, "end": 66, "id": 10}, {"text": "with", "start": 67, "end": 71, "id": 11}, {"text": "ATP1A2", "start": 72, "end": 78, "id": 12}, {"text": "mutation", "start": 79, "end": 87, "id": 13}, {"text": ".", "start": 87, "end": 88, "id": 14}, {"text": "Compared", "start": 89, "end": 97, "id": 15}, {"text": "with", "start": 98, "end": 102, "id": 16}, {"text": "interictal", "start": 103, "end": 113, "id": 17}, {"text": "PET", "start": 114, "end": 117, "id": 18}, {"text": "(", "start": 118, "end": 119, "id": 19}, {"text": "low", "start": 119, "end": 122, "id": 20}, {"text": "panels", "start": 123, "end": 129, "id": 21}, {"text": ")", "start": 129, "end": 130, "id": 22}, {"text": ",", "start": 130, "end": 131, "id": 23}, {"text": "ictal", "start": 132, "end": 137, "id": 24}, {"text": "images", "start": 138, "end": 144, "id": 25}, {"text": "(", "start": 145, "end": 146, "id": 26}, {"text": "upper", "start": 146, "end": 151, "id": 27}, {"text": "panels", "start": 152, "end": 158, "id": 28}, {"text": ")", "start": 158, "end": 159, "id": 29}, {"text": "show", "start": 160, "end": 164, "id": 30}, {"text": "significant", "start": 165, "end": 176, "id": 31}, {"text": "hypometabolism", "start": 177, "end": 191, "id": 32}, {"text": "in", "start": 192, "end": 194, "id": 33}, {"text": "bilateral", "start": 195, "end": 204, "id": 34}, {"text": "cerebellar", "start": 205, "end": 215, "id": 35}, {"text": "hemispheres", "start": 216, "end": 227, "id": 36}, {"text": ".", "start": 227, "end": 228, "id": 37}]}
{"pdf_hash": "de3573b3dfbf3513da00ac32c86120d787824878", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4.-0steochondritis dissecans with free condylar fragment in 36-year-old man with temporomandibular joint pain for 4 months before imaging and intermittent pain, crepitus, and locking at time of imaging. A, Sagittal closed-mouth image, 600/20, through mid condyle reveals sharply defined posterior condylar defect (black arrow) and normal meniscus (curved arrow). B, Image through medial pole of condyle (c) reveals viable condylar fragment (arrow) with mildly diminished signal. 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{"pdf_hash": "f967b14da095f20cccd82275a22bb5eacf4bf052", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3 (A-E): 11 year old male child presented with Stage II of Idiopathic Chondrolysis of Hip, who presented with chronic right hip pain. (A) Fat suppressed coronal T2 weighted image shows a wedge shaped hyperintensity in the right femoral head. Acetabular oedema seen around the triradiate cartilage involving ilium and ischium. Joint effusion and synovial thickening are also seen. (B) Fat suppressed axial T2 weighted image shows a wedge shaped hyperintensity in the right femoral head. Acetabular oedema seen around the triradiate cartilage involving ilium and ischium. Joint effusion and synovial thickening are also seen. (C) Coronal T1weighted image shows wedge shaped hypointensity in the right femoral head. (D and E) Radiographs shows pelvic tilt, diffuse right hip joint space narrowing, periarticular osteopaenia without femoral head deformity and advanced degenerative changes D", "width": 674, "height": 452, "subcaptions": {"a": [31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71], "b": [72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112], "c": [128, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "d": [129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155], "e": [129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155]}, "subfigures": [{"id": 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{"pdf_hash": "25cc4bb02717e48c7949ca87e95a34e5656ac01e", "fig_key": "Figure5", "fig_uri": "5-Figure5-1.png", "text": "Figure 5. a\u2013d. Examples of axial reformats demonstrating low-quality contrast-enhanced renal CTA studies necessary to reliably exclude renal artery thrombosis and stenosis. Panels (a) and (b) show early arterial timing of low nonhomogeneous contrast opacification below the 211 HU threshold in the renal arteries, while renal veins and inferior vena cava demonstrate opacification below 50 HU. 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{"pdf_hash": "c2c5e0e3b5d0dea2115fd4120bb0b237c03dde97", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Fig. 2 CT pure axial images showing examples of extracardiac diseases. a Axial image at the supra-diaphragmatic level showing a large hiatal hernia (arrow) extending into the thoracic cavity through the esophageal hiatus of the diaphragm (arrowheads). b Axial image with lung window, at the heart level, showing pulmonary consolidation (asterisk) with air bronchogram in the posterior-basal segment of the right lung. c Axial image with lung window, at the pulmonary artery bifurcation level, showing a significant anterior mainly para-mediastinal pneumothorax (asterisk) of the left lung", "width": 578, "height": 1520, "subcaptions": {"a": [13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "b": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 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{"pdf_hash": "0244fcd3d27ed4e6562c4afd709ffcc07f26eec6", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Figure 2. A, Indirect immunohistochemistry with confocal microscopy\u2013enhanced imaging illustrates the positive staining (arrows) localized along the inner nuclear and nerve fiber layers. Very faint staining was also noted along the outer nuclear layers. This reaction was obtained using serum from patient 1 as the primary antibody and goat antihuman Cy3 red color as the secondary antibody on a healthy, unfixed, frozen human retina. B, There was no reaction using serum from a healthy control as the primary antibody and goat antihuman Cy3 red color as the secondary antibody on a healthy unfixed, frozen human retina (blue, 4 ,6-diamidino-2-phenylindole dihydrochloride staining for nuclei; green, autofluorescent staining for retinal pigment epithelium lipofuscin; original magnification 150).", "width": 866, "height": 582, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74], "b": [75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108]}, "subfigures": [{"id": "62b7f8fa-e468-430f-b7ed-fd8eb7648151", "label": "a", "points": [[2.1, 1.1], [2.1, 547], [407, 547], [407, 1.1]], "color": 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{"pdf_hash": "b4eec2bf0b112818c0e5e89d2bcf33a992daa025", "fig_key": "Figure3", "fig_uri": "3-Figure3-1.png", "text": "Figure 3. Ultrastructural analysis of the Chromatoid body formation in R. philippinarum (TEM). (A) Cytoplasmic area around the Chromatoid body (Cb) in an early spermatid (1 mm bar); nu \u2013 nucleus; g \u2013 Golgi apparatus. (B) A detail from A showing the region among nucleus, mitochondria (m) and the Cb (250 nm bar). (C) A detail of B: nuclear material outflows from a nuclear pore (np) and a polyribosome formed by ribosomes of two different sizes is visible, the smallest are indicated by an arrow (250 nm bar). (D) The Cb is located close to the nuclear membrane and surrounded by empty mitochondria, some of which showing extruded cristae (c) (500 nm bar). arrow \u2013 polyribosome. doi:10.1371/journal.pone.0028194.g003", "width": 664, "height": 686, "subcaptions": {"a": [17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47], "b": [48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73], "c": [74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117], "d": [128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127]}, "subfigures": [{"id": "d209ed44-a406-4398-a8ff-c92e5bca769f", "label": "a", "points": [[34.8, 8], [34.8, 444.4], [395.6, 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{"pdf_hash": "3f877a3fad9efba7fbc2b43a83476e2c97cf88df", "fig_key": "Figure2", "fig_uri": "2-Figure2-1.png", "text": "Fig. 2 A: Chest X-ray demonstrated the rise of the density (arrows) in right side thorax due to the chest wall collapse. B : Postoperative chest X-ray demonstrated that improvement of this density rising in right side thorax.", "width": 944, "height": 456, "subcaptions": {"a": [3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27], "b": [29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47]}, "subfigures": [{"id": "77be1328-64ae-4d68-bd35-581f3dae9ca0", "label": "a", "points": [[6.2, 2], [6.2, 424], [425.3, 424], [425.3, 2]], "color": "yellow"}, {"id": "968f4f82-06db-4d77-922a-a808faaad872", "label": "b", "points": [[434.2, 2], [434.2, 425.5], [860.7, 425.5], [860.7, 2]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": "A", "start": 7, "end": 8, "id": 3}, {"text": ":", "start": 8, "end": 9, "id": 4}, {"text": "Chest", "start": 10, "end": 15, "id": 5}, {"text": "X", "start": 16, "end": 17, "id": 6}, {"text": "-", "start": 17, "end": 18, "id": 7}, {"text": "ray", "start": 18, "end": 21, "id": 8}, {"text": "demonstrated", "start": 22, "end": 34, "id": 9}, {"text": "the", "start": 35, "end": 38, "id": 10}, {"text": "rise", "start": 39, "end": 43, "id": 11}, {"text": "of", "start": 44, "end": 46, "id": 12}, {"text": "the", "start": 47, "end": 50, "id": 13}, {"text": "density", "start": 51, "end": 58, "id": 14}, {"text": "(", "start": 59, "end": 60, "id": 15}, {"text": "arrows", "start": 60, "end": 66, "id": 16}, {"text": ")", "start": 66, "end": 67, "id": 17}, {"text": "in", "start": 68, "end": 70, "id": 18}, {"text": "right", "start": 71, "end": 76, "id": 19}, {"text": "side", "start": 77, "end": 81, "id": 20}, {"text": "thorax", "start": 82, "end": 88, "id": 21}, {"text": "due", "start": 89, "end": 92, "id": 22}, {"text": "to", "start": 93, "end": 95, "id": 23}, {"text": "the", "start": 96, "end": 99, "id": 24}, {"text": "chest", "start": 100, "end": 105, "id": 25}, {"text": "wall", "start": 106, "end": 110, "id": 26}, {"text": "collapse", "start": 111, "end": 119, "id": 27}, {"text": ".", "start": 119, "end": 120, "id": 28}, {"text": "B", "start": 121, "end": 122, "id": 29}, {"text": ":", "start": 123, "end": 124, "id": 30}, {"text": "Postoperative", "start": 125, "end": 138, "id": 31}, {"text": "chest", "start": 139, "end": 144, "id": 32}, {"text": "X", "start": 145, "end": 146, "id": 33}, {"text": "-", "start": 146, "end": 147, "id": 34}, {"text": "ray", "start": 147, "end": 150, "id": 35}, {"text": "demonstrated", "start": 151, "end": 163, "id": 36}, {"text": "that", "start": 164, "end": 168, "id": 37}, {"text": "improvement", "start": 169, "end": 180, "id": 38}, {"text": "of", "start": 181, "end": 183, "id": 39}, {"text": "this", "start": 184, "end": 188, "id": 40}, {"text": "density", "start": 189, "end": 196, "id": 41}, {"text": "rising", "start": 197, "end": 203, "id": 42}, {"text": "in", "start": 204, "end": 206, "id": 43}, {"text": "right", "start": 207, "end": 212, "id": 44}, {"text": "side", "start": 213, "end": 217, "id": 45}, {"text": "thorax", "start": 218, "end": 224, "id": 46}, {"text": ".", "start": 224, "end": 225, "id": 47}]}
{"pdf_hash": "67f3b10de8834eeed1379f988c67fa433171d4b5", "fig_key": "Figure4", "fig_uri": "5-Figure4-1.png", "text": "Fig. 4. Loss of the notochord and formation of the vertebral column were defective in Hsp47 cKO embryos. Sagittal sections of the sacral vertebral column of E14.5-18.5 and neonatal (P0) Hsp47 flox/flox control (A,C,E,G) and Hsp47 cKO (Hsp47 flox/flox ; Col2a1-Cre) (B,D,F,H) mice were stained with Hematoxylin and Eosin. In control mice, the notochord gradually expanded at the intervertebral disc areas to form a nucleus pulposus (np) and vanished within the vertebral bodies (vb; A,C,E,G). In Hsp47 cKO mice the notochord was still present at E14.5 (B), and disorganized vertebral discs and vertebral bodies were observed at later stages (F,H). n, notochord; np, nucleus pulposus; vb, vertebral body. The arrowhead indicates the acellular notochordal tube. 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{"pdf_hash": "671b142c0f384ef8bb0bc6c8569474c55828cde0", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Figure 2. A CT scan of the chest demonstrate a thick-walled cavity and a mass with small nodular shadows in the right lower lobe (A). A wedge shaped subpleural consolidation is demonstrated in the right middle lobe as well as mosaic perfusion patterns in the bilateral lung fields (B). 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{"pdf_hash": "6791b93d194a9c215df2bfdeec078c9923954a01", "fig_key": "Figure6", "fig_uri": "4-Figure6-1.png", "text": "Figure 6. Infant female with sirenomelia. Postpartum photo (left) and radiograph (right) demonstrate fused and abnormally positioned legs with flipper/mermaid deformity.", "width": 1402, "height": 678, "subcaptions": {"a": [8, 9, 10, 11, 12], "b": [14, 15, 16, 17]}, "subfigures": [{"id": "c06a6125-4307-4d0e-bc6a-226d293a31f3", "label": "a", "points": [[4.5, 3.1], [4.5, 632.1], [633.5, 632.1], [633.5, 3.1]], "color": "yellow"}, {"id": "e8d1fccd-d27c-4348-bd26-01616fd53542", "label": "b", "points": [[664.5, -1.3], [664.5, 634.4], [1393.2, 634.4], [1393.2, -1.3]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "6", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Infant", "start": 10, "end": 16, "id": 3}, {"text": "female", "start": 17, "end": 23, "id": 4}, {"text": "with", "start": 24, "end": 28, "id": 5}, {"text": "sirenomelia", "start": 29, "end": 40, "id": 6}, {"text": ".", "start": 40, "end": 41, "id": 7}, {"text": "Postpartum", "start": 42, "end": 52, "id": 8}, {"text": "photo", "start": 53, "end": 58, "id": 9}, {"text": "(", "start": 59, "end": 60, "id": 10}, {"text": "left", "start": 60, "end": 64, "id": 11}, {"text": ")", "start": 64, "end": 65, "id": 12}, {"text": "and", "start": 66, "end": 69, "id": 13}, {"text": "radiograph", "start": 70, "end": 80, "id": 14}, {"text": "(", "start": 81, "end": 82, "id": 15}, {"text": "right", "start": 82, "end": 87, "id": 16}, {"text": ")", "start": 87, "end": 88, "id": 17}, {"text": "demonstrate", "start": 89, "end": 100, "id": 18}, {"text": "fused", "start": 101, "end": 106, "id": 19}, {"text": "and", "start": 107, "end": 110, "id": 20}, {"text": "abnormally", "start": 111, "end": 121, "id": 21}, {"text": "positioned", "start": 122, "end": 132, "id": 22}, {"text": "legs", "start": 133, "end": 137, "id": 23}, {"text": "with", "start": 138, "end": 142, "id": 24}, {"text": "flipper", "start": 143, "end": 150, "id": 25}, {"text": "/", "start": 150, "end": 151, "id": 26}, {"text": "mermaid", "start": 151, "end": 158, "id": 27}, {"text": "deformity", "start": 159, "end": 168, "id": 28}, {"text": ".", "start": 168, "end": 169, "id": 29}]}
{"pdf_hash": "e7ef512ad301aeea2e5b1ec630d41f0fd9a5568b", "fig_key": "Figure4", "fig_uri": "4-Figure4-1.png", "text": "Fig. 4. (A) Bent or globoid elastic fibers and rare fibroblasts are visible in imaging degenerated with eosinophilic thick collagen (H&E, \u00c2200). (B) Extending and globoid elastic fibers observed using Verhoeffevan Gieson's histochemical dye.", "width": 936, "height": 386, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29], "b": [30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "fb9a1dd9-a4b2-4ca9-a650-972db2a5d0f8", "label": "a", "points": [[30.7, 30.8], [30.7, 351.7], [464, 351.7], [464, 30.8]], "color": "yellow"}, {"id": "46e10443-dbc3-49ac-be88-278b1a9a7e78", "label": "b", "points": [[486.2, 29.3], [486.2, 348.7], [917.9, 348.7], [917.9, 29.3]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "4", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "(", "start": 8, "end": 9, "id": 4}, {"text": "A", "start": 9, "end": 10, "id": 5}, {"text": ")", "start": 10, "end": 11, "id": 6}, {"text": "Bent", "start": 12, "end": 16, "id": 7}, {"text": "or", "start": 17, "end": 19, "id": 8}, {"text": "globoid", "start": 20, "end": 27, "id": 9}, {"text": "elastic", "start": 28, "end": 35, "id": 10}, {"text": "fibers", "start": 36, "end": 42, "id": 11}, {"text": "and", "start": 43, "end": 46, "id": 12}, {"text": "rare", "start": 47, "end": 51, "id": 13}, {"text": "fibroblasts", "start": 52, "end": 63, "id": 14}, {"text": "are", "start": 64, "end": 67, "id": 15}, {"text": "visible", "start": 68, "end": 75, "id": 16}, {"text": "in", "start": 76, "end": 78, "id": 17}, {"text": "imaging", "start": 79, "end": 86, "id": 18}, {"text": "degenerated", "start": 87, "end": 98, "id": 19}, {"text": "with", "start": 99, "end": 103, "id": 20}, {"text": "eosinophilic", "start": 104, "end": 116, "id": 21}, {"text": "thick", "start": 117, "end": 122, "id": 22}, {"text": "collagen", "start": 123, "end": 131, "id": 23}, {"text": "(", "start": 132, "end": 133, "id": 24}, {"text": "H&E", "start": 133, "end": 136, "id": 25}, {"text": ",", "start": 136, "end": 137, "id": 26}, {"text": "\u00c2200", "start": 138, "end": 142, "id": 27}, {"text": ")", "start": 142, "end": 143, "id": 28}, {"text": ".", "start": 143, "end": 144, "id": 29}, {"text": "(", "start": 145, "end": 146, "id": 30}, {"text": "B", "start": 146, "end": 147, "id": 31}, {"text": ")", "start": 147, "end": 148, "id": 32}, {"text": "Extending", "start": 149, "end": 158, "id": 33}, {"text": "and", "start": 159, "end": 162, "id": 34}, {"text": "globoid", "start": 163, "end": 170, "id": 35}, {"text": "elastic", "start": 171, "end": 178, "id": 36}, {"text": "fibers", "start": 179, "end": 185, "id": 37}, {"text": "observed", "start": 186, "end": 194, "id": 38}, {"text": "using", "start": 195, "end": 200, "id": 39}, {"text": "Verhoeffevan", "start": 201, "end": 213, "id": 40}, {"text": "Gieson", "start": 214, "end": 220, "id": 41}, {"text": "'s", "start": 220, "end": 222, "id": 42}, {"text": "histochemical", "start": 223, "end": 236, "id": 43}, {"text": "dye", "start": 237, "end": 240, "id": 44}, {"text": ".", "start": 240, "end": 241, "id": 45}]}
{"pdf_hash": "4262493bb5199c7946f1650bf1fbeac023d59438", "fig_key": "Figure3", "fig_uri": "5-Figure3-1.png", "text": "Figure 3. Bilateral endometriomas, solid endometriosis of the posterior uterus, and left-sided peritoneal inclusion cyst in a 43-year-old woman. (a, b) Axial T1-weighted in-phase (a) and fat-suppressed opposed-phase (b) gradientecho MR images show bilateral hyperintense adnexal lesions (arrows) that retain high signal intensity with fat suppression. A peritoneal inclusion cyst ( * ) is also shown posterior to the uterus (U). Susceptibility artifacts anterior to the rectus muscles (arrowheads in a) indicate that the patient has undergone a previous surgical procedure. (c) Axial T2-weighted MR image shows shading within the bilateral endometriomas (straight arrows). The normal endometrial complex and junctional zone are shown in the anterior uterus (arrowheads). 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{"pdf_hash": "b3ef38f28e6be1ceb8cf6d0dcd8c60513939d7ba", "fig_key": "Figure3", "fig_uri": "6-Figure3-1.png", "text": "Figure 3: (a) Postmortem CT and (b-d) and arterial phase postmortem CT angiography images in a 59-year-old woman who died of internal exsanguination shortly after Whipple surgery. (a) A large left-sided hemothorax with mediastinal shift to the right. During the surgery, supraceliac clamping of the abdominal aorta was performed to stop intraperitoneal bleeding. The clamp was later loosened but left in place (arrow in b). The fatal hemothorax was caused by hemorrhage from the left 11th intercostal artery, which was torn near its origin from the aorta just above the diaphragm during placement of the clamp. The contrast media extravasation from the artery's origin, reaching cranially into the thorax (arrows in b, c, and d), is displayed on arterial phase postmortem CT angiographic images (c and d). This finding may have been difficult to detect at autopsy because of the small size and location of the vessel. In this case it could not be displayed at autopsy because of large amounts of intraperitoneal and intrathoracic clotted blood, and multiple previous abdominal operations with extensive scar tissue formation and adhesions.", "width": 910, "height": 994, "subcaptions": {"a": [3, 4, 5, 6, 7, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52], "b": [128, 129, 130, 131, 132, 133, 134, 135, 136, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 154, 157, 158, 137, 138, 153, 139, 155, 140, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 143, 144, 156, 142, 145, 151, 141, 146, 147, 148, 149, 152, 150, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127], "c": [128, 129, 130, 131, 132, 133, 134, 135, 136, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 154, 157, 158, 137, 138, 153, 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{"pdf_hash": "ddf8441e68ece5171c88fde83625bcdafa9141cf", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. (A) Transesophageal echocardiogram (TEE) short-axis view of the aortic valve shows round echo-density mass (*), between the left and noncoronary cusps, in proximity to the left main ostium. (B) TEE long-axis view of the aortic valve as well as the ascending aorta demonstrates papillary fibroelastoma (PFE) location. (C) PFE noted on 3-dimensional TEE long-axis view of the aortic valve, aortic root, and ascending aorta. (D) T2-weighted cardiac magnetic resonance imaging confirms the density noted in the aortic root, attached to the sinotubular junction. 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{"pdf_hash": "61ee9c4089a77d9d67d5ed52b966611ac935bffb", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Figure 1 Immunohistochemical staining with D07 monoclonal antibody. A Intense nuclear staining. B greater than 75% TP53 nuclear reactivity (diffuse pattern)", "width": 982, "height": 1334, "subcaptions": {"a": [9, 10, 11, 12, 13], "b": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25]}, "subfigures": [{"id": "503d44e9-8e7d-43fe-a927-2a07fa088bfa", "label": "a", "points": [[3.9, 19.3], [3.9, 650.6], [973.5, 650.6], [973.5, 19.3]], "color": "yellow"}, {"id": "04dd138a-00dd-4bbe-b450-fc233eb37a01", "label": "b", "points": [[3.9, 698.7], [3.9, 1328.5], [967.3, 1328.5], [967.3, 698.7]], "color": "cyan"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": "Immunohistochemical", "start": 9, "end": 28, "id": 2}, {"text": "staining", "start": 29, "end": 37, "id": 3}, {"text": "with", "start": 38, "end": 42, "id": 4}, {"text": "D07", "start": 43, "end": 46, "id": 5}, {"text": "monoclonal", "start": 47, "end": 57, "id": 6}, {"text": "antibody", "start": 58, "end": 66, "id": 7}, {"text": ".", "start": 66, "end": 67, "id": 8}, {"text": "A", "start": 68, "end": 69, "id": 9}, {"text": "Intense", "start": 70, "end": 77, "id": 10}, {"text": "nuclear", "start": 78, "end": 85, "id": 11}, {"text": "staining", "start": 86, "end": 94, "id": 12}, {"text": ".", "start": 94, "end": 95, "id": 13}, {"text": "B", "start": 96, "end": 97, "id": 14}, {"text": "greater", "start": 98, "end": 105, "id": 15}, {"text": "than", "start": 106, "end": 110, "id": 16}, {"text": "75", "start": 111, "end": 113, "id": 17}, {"text": "%", "start": 113, "end": 114, "id": 18}, {"text": "TP53", "start": 115, "end": 119, "id": 19}, {"text": "nuclear", "start": 120, "end": 127, "id": 20}, {"text": "reactivity", "start": 128, "end": 138, "id": 21}, {"text": "(", "start": 139, "end": 140, "id": 22}, {"text": "diffuse", "start": 140, "end": 147, "id": 23}, {"text": "pattern", "start": 148, "end": 155, "id": 24}, {"text": ")", "start": 155, "end": 156, "id": 25}]}
{"pdf_hash": "26b2405a75592a3044157bbb12a43ed81e9dd155", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2 Coronary microvascular dysfunction in the absence of atherosclerosis in a 58-year-old man with atypical angina pectoris, history of smoking, family history of coronary artery disease, and ischaemia on exercise ECG. Myocardial blood flow (MBF) during adenosine stress was moderately reduced in all vessel areas (A, global MBF 1.9 mL/g/min). MBF at rest was homogenously distributed (B) and CFR was reduced being 2.2. Coronary CT angiography images show the absence of atherosclerosis in the left anterior descending (C) and circumflex (D) arteries and the right coronary artery (E). 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{"pdf_hash": "a7e0a3013e766d38ebe782af91f5dafd2a9a7b04", "fig_key": "Figure2", "fig_uri": "3-Figure2-1.png", "text": "Fig. 2. a High magnification of the hyposignal in the hippocampus on a T2*-weighted GRE MRI sequence. b Iron deposits (arrows) in the hippocampus on the corresponding histological section of the hippocampus, stained with hematoxylin-eosin.", "width": 938, "height": 452, "subcaptions": {"a": [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21], "b": [22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45]}, "subfigures": [{"id": "a4955afb-1dcb-4886-aa1c-ff1ea6a9c722", "label": "a", "points": [[0.2, 9.4], [0.2, 448], [456.7, 448], [456.7, 9.4]], "color": "yellow"}, {"id": "25161e2b-589e-478d-be6d-13ba5be9765b", "label": "b", "points": [[467, 9.4], [467, 451], [936.8, 451], [936.8, 9.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "2", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "a", "start": 8, "end": 9, "id": 4}, {"text": "High", "start": 10, "end": 14, "id": 5}, {"text": "magnification", "start": 15, "end": 28, "id": 6}, {"text": "of", "start": 29, "end": 31, "id": 7}, {"text": "the", "start": 32, "end": 35, "id": 8}, {"text": "hyposignal", "start": 36, "end": 46, "id": 9}, {"text": "in", "start": 47, "end": 49, "id": 10}, {"text": "the", "start": 50, "end": 53, "id": 11}, {"text": "hippocampus", "start": 54, "end": 65, "id": 12}, {"text": "on", "start": 66, "end": 68, "id": 13}, {"text": "a", "start": 69, "end": 70, "id": 14}, {"text": "T2", "start": 71, "end": 73, "id": 15}, {"text": "*", "start": 73, "end": 74, "id": 16}, {"text": "-weighted", "start": 74, "end": 83, "id": 17}, {"text": "GRE", "start": 84, "end": 87, "id": 18}, {"text": "MRI", "start": 88, "end": 91, "id": 19}, {"text": "sequence", "start": 92, "end": 100, "id": 20}, {"text": ".", "start": 100, "end": 101, "id": 21}, {"text": "b", "start": 102, "end": 103, "id": 22}, {"text": "Iron", "start": 104, "end": 108, "id": 23}, {"text": "deposits", "start": 109, "end": 117, "id": 24}, {"text": "(", "start": 118, "end": 119, "id": 25}, {"text": "arrows", "start": 119, "end": 125, "id": 26}, {"text": ")", "start": 125, "end": 126, "id": 27}, {"text": "in", "start": 127, "end": 129, "id": 28}, {"text": "the", "start": 130, "end": 133, "id": 29}, {"text": "hippocampus", "start": 134, "end": 145, "id": 30}, {"text": "on", "start": 146, "end": 148, "id": 31}, {"text": "the", "start": 149, "end": 152, "id": 32}, {"text": "corresponding", "start": 153, "end": 166, "id": 33}, {"text": "histological", "start": 167, "end": 179, "id": 34}, {"text": "section", "start": 180, "end": 187, "id": 35}, {"text": "of", "start": 188, "end": 190, "id": 36}, {"text": "the", "start": 191, "end": 194, "id": 37}, {"text": "hippocampus", "start": 195, "end": 206, "id": 38}, {"text": ",", "start": 206, "end": 207, "id": 39}, {"text": "stained", "start": 208, "end": 215, "id": 40}, {"text": "with", "start": 216, "end": 220, "id": 41}, {"text": "hematoxylin", "start": 221, "end": 232, "id": 42}, {"text": "-", "start": 232, "end": 233, "id": 43}, {"text": "eosin", "start": 233, "end": 238, "id": 44}, {"text": ".", "start": 238, "end": 239, "id": 45}]}
{"pdf_hash": "942a523a74c19a9a92c3ec5389fea57ad6a81e8e", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Fig. 1. A 58-year-old female patient with sporadic CJD. 1A: Reduced diffusion is noted in the parasagittal cortices bilaterally as well as the basal ganglia, with additional involvement of the thalami, specifically pulvinar nuclei (arrowheads). 1B: On FLAIR, hyperintensity is noted only in the bilateral parasagittal cerebral cortices.", "width": 902, "height": 488, "subcaptions": {"a": [14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45], "b": [46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61]}, "subfigures": [{"id": "08d1e56e-6f04-4e50-a220-4406ef820b76", "label": "a", "points": [[1.4, 7.1], [1.4, 487.4], [421.8, 487.4], [421.8, 7.1]], "color": "yellow"}, {"id": "dc75d483-9ad0-48c3-80f8-8d1ee0ddc22b", "label": "b", "points": [[447.5, 487.4], [447.5, 4.3], [862.1, 4.3], [862.1, 487.4]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "1", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "A", "start": 8, "end": 9, "id": 4}, {"text": "58-year", "start": 10, "end": 17, "id": 5}, {"text": "-", "start": 17, "end": 18, "id": 6}, {"text": "old", "start": 18, "end": 21, "id": 7}, {"text": "female", "start": 22, "end": 28, "id": 8}, {"text": "patient", "start": 29, "end": 36, "id": 9}, {"text": "with", "start": 37, "end": 41, "id": 10}, {"text": "sporadic", "start": 42, "end": 50, "id": 11}, {"text": "CJD", "start": 51, "end": 54, "id": 12}, {"text": ".", "start": 54, "end": 55, "id": 13}, {"text": "1A", "start": 56, "end": 58, "id": 14}, {"text": ":", "start": 58, "end": 59, "id": 15}, {"text": "Reduced", "start": 60, "end": 67, "id": 16}, {"text": "diffusion", "start": 68, "end": 77, "id": 17}, {"text": "is", "start": 78, "end": 80, "id": 18}, {"text": "noted", "start": 81, "end": 86, "id": 19}, {"text": "in", "start": 87, "end": 89, "id": 20}, {"text": "the", "start": 90, "end": 93, "id": 21}, {"text": "parasagittal", "start": 94, "end": 106, "id": 22}, {"text": "cortices", "start": 107, "end": 115, "id": 23}, {"text": "bilaterally", "start": 116, "end": 127, "id": 24}, {"text": "as", "start": 128, "end": 130, "id": 25}, {"text": "well", "start": 131, "end": 135, "id": 26}, {"text": "as", "start": 136, "end": 138, "id": 27}, {"text": "the", "start": 139, "end": 142, "id": 28}, {"text": "basal", "start": 143, "end": 148, "id": 29}, {"text": "ganglia", "start": 149, "end": 156, "id": 30}, {"text": ",", "start": 156, "end": 157, "id": 31}, {"text": "with", "start": 158, "end": 162, "id": 32}, {"text": "additional", "start": 163, "end": 173, "id": 33}, {"text": "involvement", "start": 174, "end": 185, "id": 34}, {"text": "of", "start": 186, "end": 188, "id": 35}, {"text": "the", "start": 189, "end": 192, "id": 36}, {"text": "thalami", "start": 193, "end": 200, "id": 37}, {"text": ",", "start": 200, "end": 201, "id": 38}, {"text": "specifically", "start": 202, "end": 214, "id": 39}, {"text": "pulvinar", "start": 215, "end": 223, "id": 40}, {"text": "nuclei", "start": 224, "end": 230, "id": 41}, {"text": "(", "start": 231, "end": 232, "id": 42}, {"text": "arrowheads", "start": 232, "end": 242, "id": 43}, {"text": ")", "start": 242, "end": 243, "id": 44}, {"text": ".", "start": 243, "end": 244, "id": 45}, {"text": "1B", "start": 245, "end": 247, "id": 46}, {"text": ":", "start": 247, "end": 248, "id": 47}, {"text": "On", "start": 249, "end": 251, "id": 48}, {"text": "FLAIR", "start": 252, "end": 257, "id": 49}, {"text": ",", "start": 257, "end": 258, "id": 50}, {"text": "hyperintensity", "start": 259, "end": 273, "id": 51}, {"text": "is", "start": 274, "end": 276, "id": 52}, {"text": "noted", "start": 277, "end": 282, "id": 53}, {"text": "only", "start": 283, "end": 287, "id": 54}, {"text": "in", "start": 288, "end": 290, "id": 55}, {"text": "the", "start": 291, "end": 294, "id": 56}, {"text": "bilateral", "start": 295, "end": 304, "id": 57}, {"text": "parasagittal", "start": 305, "end": 317, "id": 58}, {"text": "cerebral", "start": 318, "end": 326, "id": 59}, {"text": "cortices", "start": 327, "end": 335, "id": 60}, {"text": ".", "start": 335, "end": 336, "id": 61}]}
{"pdf_hash": "0694685357724ff0dc34974b578ed44ef47487b8", "fig_key": "Figure2", "fig_uri": "4-Figure2-1.png", "text": "Figure 2 The disease phenotype: (a,b) Dysmorphic features seen in two of the affected individuals IV-4 at (a) and V-1 (b) at ages 5 and 9 months and 6 years, respectively. (c) Brain magnetic resonance imaging (MRI) of an affected individual V-1. Sagital T2 image demonstrates partial agenesis of corpus calosum and inferior vermis hypoplasia with moderately enlarged fourth ventricle cyst. 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{"pdf_hash": "bcc60a004217aa8d0b32c186a3e842c09fd770ef", "fig_key": "Figure3", "fig_uri": "2-Figure3-1.png", "text": "Fig. 3. Coronary multi-detector CT findings. Anomalous coronary arteriovenous fistulas from proximal left main artery to pulmonary artery (A), proximal left anterior descending artery to pulmonary artery (B), proximal right coronary artery to pulmonary artery (C).", "width": 1418, "height": 458, "subcaptions": {"a": [16, 17, 18, 19, 20, 21, 22, 23, 24, 25], "b": [32, 33, 34, 35, 36, 37, 27, 28, 29, 30, 31], "c": [39, 40, 41, 42, 43, 44, 45, 46, 47, 48]}, "subfigures": [{"id": "d904e1e1-e36a-4c75-a48d-ec688ec91870", "label": "a", "points": [[3.4, 0], [3.4, 427.9], [467.1, 427.9], [467.1, 0]], "color": "yellow"}, {"id": "0dcf7f87-161f-4ae6-98b4-359c4148058e", "label": "b", "points": [[478.3, 4.5], [478.3, 425.7], [942, 425.7], [942, 4.5]], "color": "cyan"}, {"id": "e0e33adb-2892-4933-8af1-efe3190c35b0", "label": "c", "points": [[953.2, 2.2], [953.2, 423.4], [1412.5, 423.4], [1412.5, 2.2]], "color": "magenta"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "3", "start": 5, "end": 6, "id": 2}, {"text": ".", "start": 6, "end": 7, "id": 3}, {"text": "Coronary", "start": 8, "end": 16, "id": 4}, {"text": "multi", "start": 17, "end": 22, "id": 5}, {"text": "-", "start": 22, "end": 23, "id": 6}, {"text": "detector", "start": 23, "end": 31, "id": 7}, {"text": "CT", "start": 32, "end": 34, "id": 8}, {"text": "findings", "start": 35, "end": 43, "id": 9}, {"text": ".", "start": 43, "end": 44, "id": 10}, {"text": "Anomalous", "start": 45, "end": 54, "id": 11}, {"text": "coronary", "start": 55, "end": 63, "id": 12}, {"text": "arteriovenous", "start": 64, "end": 77, "id": 13}, {"text": "fistulas", "start": 78, "end": 86, "id": 14}, {"text": "from", "start": 87, "end": 91, "id": 15}, {"text": "proximal", "start": 92, "end": 100, "id": 16}, {"text": "left", "start": 101, "end": 105, "id": 17}, {"text": "main", "start": 106, "end": 110, "id": 18}, {"text": "artery", "start": 111, "end": 117, "id": 19}, {"text": "to", "start": 118, "end": 120, "id": 20}, {"text": "pulmonary", "start": 121, "end": 130, "id": 21}, {"text": "artery", "start": 131, "end": 137, "id": 22}, {"text": "(", "start": 138, "end": 139, "id": 23}, {"text": "A", "start": 139, "end": 140, "id": 24}, {"text": ")", "start": 140, "end": 141, "id": 25}, {"text": ",", "start": 141, "end": 142, "id": 26}, {"text": "proximal", "start": 143, "end": 151, "id": 27}, {"text": "left", "start": 152, "end": 156, "id": 28}, {"text": "anterior", "start": 157, "end": 165, "id": 29}, {"text": "descending", "start": 166, "end": 176, "id": 30}, {"text": "artery", "start": 177, "end": 183, "id": 31}, {"text": "to", "start": 184, "end": 186, "id": 32}, {"text": "pulmonary", "start": 187, "end": 196, "id": 33}, {"text": "artery", "start": 197, "end": 203, "id": 34}, {"text": "(", "start": 204, "end": 205, "id": 35}, {"text": "B", "start": 205, "end": 206, "id": 36}, {"text": ")", "start": 206, "end": 207, "id": 37}, {"text": ",", "start": 207, "end": 208, "id": 38}, {"text": "proximal", "start": 209, "end": 217, "id": 39}, {"text": "right", "start": 218, "end": 223, "id": 40}, {"text": "coronary", "start": 224, "end": 232, "id": 41}, {"text": "artery", "start": 233, "end": 239, "id": 42}, {"text": "to", "start": 240, "end": 242, "id": 43}, {"text": "pulmonary", "start": 243, "end": 252, "id": 44}, {"text": "artery", "start": 253, "end": 259, "id": 45}, {"text": "(", "start": 260, "end": 261, "id": 46}, {"text": "C", "start": 261, "end": 262, "id": 47}, {"text": ")", "start": 262, "end": 263, "id": 48}, {"text": ".", "start": 263, "end": 264, "id": 49}]}
{"pdf_hash": "8683f96a045eeb393e43b47917f84c8c8d90d3fd", "fig_key": "Figure3", "fig_uri": "7-Figure3-1.png", "text": "Figure 3. MEMRI was more sensitive for detecting early-stage MB than conventional T2w MRI. Representative examples are shown for wild-type (A, B, E, and F) and Ptch1-CKO mice (C, D, G, and H) scanned with both non-contrast T2w RARE (left panels; A, C, E, and G) and post-contrast T1w MEMRI sequences (right panels; B, D, F, and H). These images show improved tissue contrast in MEMRI compared to RARE images and show higher sensitivity for visualization of tumor tissue (*) using MEMRI (D) compared to RARE (C), especially for detection of early pretumoral lesions with MEMRI (H, arrowheads), which could not be detected with RARE (G). 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{"pdf_hash": "20c465d5747a045206e25d0d2ed2b2303159c0c4", "fig_key": "Figure6", "fig_uri": "8-Figure6-1.png", "text": "Fig. 6 Lateral compartment of male participants with a full thickness cartilage damage of the lateral femur and tibia and b) without cartilage lesions depicted using sagittal 3D VIBE MRI", "width": 1004, "height": 514, "subcaptions": {"a": [8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19], "b": [21, 22, 23, 24, 25]}, "subfigures": [{"id": "6b626ee4-d7a5-4a91-8994-be58b8a7dcde", "label": "a", "points": [[33.6, 22.7], [33.6, 484.3], [499.9, 484.3], [499.9, 22.7]], "color": "yellow"}, {"id": "39a80983-1b4d-45d7-ae00-12809bdad50b", "label": "b", "points": [[511, 19.6], [511, 484.3], [977.3, 484.3], [977.3, 19.6]], "color": "cyan"}], "tokens": [{"text": "Fig", "start": 0, "end": 3, "id": 0}, {"text": ".", "start": 3, "end": 4, "id": 1}, {"text": "6", "start": 5, "end": 6, "id": 2}, {"text": "Lateral", "start": 7, "end": 14, "id": 3}, {"text": "compartment", "start": 15, "end": 26, "id": 4}, {"text": "of", "start": 27, "end": 29, "id": 5}, {"text": "male", "start": 30, "end": 34, "id": 6}, {"text": "participants", "start": 35, "end": 47, "id": 7}, {"text": "with", "start": 48, "end": 52, "id": 8}, {"text": "a", "start": 53, "end": 54, "id": 9}, {"text": "full", "start": 55, "end": 59, "id": 10}, {"text": "thickness", "start": 60, "end": 69, "id": 11}, {"text": "cartilage", "start": 70, "end": 79, "id": 12}, {"text": "damage", "start": 80, "end": 86, "id": 13}, {"text": "of", "start": 87, "end": 89, "id": 14}, {"text": "the", "start": 90, "end": 93, "id": 15}, {"text": "lateral", "start": 94, "end": 101, "id": 16}, {"text": "femur", "start": 102, "end": 107, "id": 17}, {"text": "and", "start": 108, "end": 111, "id": 18}, {"text": "tibia", "start": 112, "end": 117, "id": 19}, {"text": "and", "start": 118, "end": 121, "id": 20}, {"text": "b", "start": 122, "end": 123, "id": 21}, {"text": ")", "start": 123, "end": 124, "id": 22}, {"text": "without", "start": 125, "end": 132, "id": 23}, {"text": "cartilage", "start": 133, "end": 142, "id": 24}, {"text": "lesions", "start": 143, "end": 150, "id": 25}, {"text": "depicted", "start": 151, "end": 159, "id": 26}, {"text": "using", "start": 160, "end": 165, "id": 27}, {"text": "sagittal", "start": 166, "end": 174, "id": 28}, {"text": "3D", "start": 175, "end": 177, "id": 29}, {"text": "VIBE", "start": 178, "end": 182, "id": 30}, {"text": "MRI", "start": 183, "end": 186, "id": 31}]}
{"pdf_hash": "b73e3e90342668dd5cb21953be47a737c0fcaf9d", "fig_key": "Figure1", "fig_uri": "3-Figure1-1.png", "text": "Fig. 1. (A) Preoperative radiograph of 77 years old female shows stable femoral neck fracture (Garden type 1). (B) Radiograph taken 29 months after internal fixation with cannulated screws shows well united fracture site but decreased horizontal shortening more than 6.5 mm compared to opposite femur. 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{"pdf_hash": "0becf5aea87542f096c9a55682904f7b77ec8811", "fig_key": "Figure1", "fig_uri": "2-Figure1-1.png", "text": "Figure 1. Endoscopic images of Case 1. Multiple white spots are seen in the gastric fornix (a) and body (b). Magnifying endoscopy observation (c) and blue laser imaging (d) show deposition of slightly elevated, round, white substance and microvasculature on its surface, which are consistent with reported features of white globe appearance.", "width": 600, "height": 464, "subcaptions": {"a": [9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20], "b": [9, 10, 11, 12, 13, 14, 15, 16, 22, 23, 24, 25], "c": [27, 28, 29, 30, 31, 32, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65], "d": [34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65]}, "subfigures": [{"id": "83a3a10f-c76b-46e8-8623-dd6c0c657917", "label": "a", "points": [[6.3, 7.8], [6.3, 231.8], [299.3, 231.8], [299.3, 7.8]], "color": "yellow"}, {"id": "e34c8835-a33d-4e25-a649-a9f48f75bcb8", "label": "b", "points": [[307.3, 5.8], [307.3, 230.8], [599.3, 230.8], [599.3, 5.8]], "color": "cyan"}, {"id": "06a82049-cc49-4969-a5b7-119b90d99ddb", "label": "c", "points": [[6.3, 238.8], [6.3, 463.8], [297.3, 463.8], [297.3, 238.8]], "color": "magenta"}, {"id": "67a52a95-5eef-41e5-acd4-ce9d870f7389", "label": "d", "points": [[308.3, 236.8], [308.3, 460.8], [596.3, 460.8], [596.3, 236.8]], "color": "springgreen"}], "tokens": [{"text": "Figure", "start": 0, "end": 6, "id": 0}, {"text": "1", "start": 7, "end": 8, "id": 1}, {"text": ".", "start": 8, "end": 9, "id": 2}, {"text": "Endoscopic", "start": 10, "end": 20, "id": 3}, {"text": "images", "start": 21, "end": 27, "id": 4}, {"text": "of", "start": 28, "end": 30, "id": 5}, {"text": "Case", "start": 31, "end": 35, "id": 6}, {"text": "1", "start": 36, "end": 37, "id": 7}, {"text": ".", "start": 37, "end": 38, "id": 8}, {"text": "Multiple", "start": 39, "end": 47, "id": 9}, {"text": "white", "start": 48, "end": 53, "id": 10}, {"text": "spots", "start": 54, "end": 59, "id": 11}, {"text": "are", "start": 60, "end": 63, "id": 12}, {"text": "seen", "start": 64, "end": 68, "id": 13}, {"text": "in", "start": 69, "end": 71, "id": 14}, {"text": "the", "start": 72, "end": 75, "id": 15}, {"text": "gastric", "start": 76, "end": 83, "id": 16}, {"text": "fornix", "start": 84, "end": 90, "id": 17}, {"text": "(", "start": 91, "end": 92, "id": 18}, {"text": "a", "start": 92, "end": 93, "id": 19}, {"text": ")", "start": 93, "end": 94, "id": 20}, {"text": "and", "start": 95, "end": 98, "id": 21}, {"text": "body", "start": 99, "end": 103, "id": 22}, {"text": "(", "start": 104, "end": 105, "id": 23}, {"text": "b", "start": 105, "end": 106, "id": 24}, {"text": ")", "start": 106, "end": 107, "id": 25}, {"text": ".", "start": 107, "end": 108, "id": 26}, {"text": "Magnifying", "start": 109, "end": 119, "id": 27}, {"text": "endoscopy", "start": 120, "end": 129, "id": 28}, {"text": "observation", "start": 130, "end": 141, "id": 29}, {"text": "(", "start": 142, "end": 143, "id": 30}, {"text": "c", "start": 143, "end": 144, "id": 31}, {"text": ")", "start": 144, "end": 145, "id": 32}, {"text": "and", "start": 146, "end": 149, "id": 33}, {"text": "blue", "start": 150, "end": 154, "id": 34}, {"text": "laser", "start": 155, "end": 160, "id": 35}, {"text": "imaging", "start": 161, "end": 168, "id": 36}, {"text": "(", "start": 169, "end": 170, "id": 37}, {"text": "d", "start": 170, "end": 171, "id": 38}, {"text": ")", "start": 171, "end": 172, "id": 39}, {"text": "show", "start": 173, "end": 177, "id": 40}, {"text": "deposition", "start": 178, "end": 188, "id": 41}, {"text": "of", "start": 189, "end": 191, "id": 42}, {"text": "slightly", "start": 192, "end": 200, "id": 43}, {"text": "elevated", "start": 201, "end": 209, "id": 44}, {"text": ",", "start": 209, "end": 210, "id": 45}, {"text": "round", "start": 211, "end": 216, "id": 46}, {"text": ",", "start": 216, "end": 217, "id": 47}, {"text": "white", "start": 218, "end": 223, "id": 48}, {"text": "substance", "start": 224, "end": 233, "id": 49}, {"text": "and", "start": 234, "end": 237, "id": 50}, {"text": "microvasculature", "start": 238, "end": 254, "id": 51}, {"text": "on", "start": 255, "end": 257, "id": 52}, {"text": "its", "start": 258, "end": 261, "id": 53}, {"text": "surface", "start": 262, "end": 269, "id": 54}, {"text": ",", "start": 269, "end": 270, "id": 55}, {"text": "which", "start": 271, "end": 276, "id": 56}, {"text": "are", "start": 277, "end": 280, "id": 57}, {"text": "consistent", "start": 281, "end": 291, "id": 58}, {"text": "with", "start": 292, "end": 296, "id": 59}, {"text": "reported", "start": 297, "end": 305, "id": 60}, {"text": "features", "start": 306, "end": 314, "id": 61}, {"text": "of", "start": 315, "end": 317, "id": 62}, {"text": "white", "start": 318, "end": 323, "id": 63}, {"text": "globe", "start": 324, "end": 329, "id": 64}, {"text": "appearance", "start": 330, "end": 340, "id": 65}, {"text": ".", "start": 340, "end": 341, "id": 66}]}